LOCUS       DBERDS010000001       118130 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.001, whole genome shotgun sequence.
ACCESSION   DBERDS010000001 DBERDS010000000
VERSION     DBERDS010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 118130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.001"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(53..379)
                     /locus_tag="ACL73E_000001"
     CDS             complement(53..379)
                     /locus_tag="ACL73E_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800065.1"
                     /translation="MILWSFDFANDHAHTFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(706..2586)
                     /locus_tag="ACL73E_000002"
     CDS             complement(706..2586)
                     /locus_tag="ACL73E_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGS0800066.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2580..3449)
                     /locus_tag="ACL73E_000003"
     CDS             complement(2580..3449)
                     /locus_tag="ACL73E_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS0800067.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3533..6178)
                     /locus_tag="ACL73E_000004"
     CDS             complement(3533..6178)
                     /locus_tag="ACL73E_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGS0800068.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPELL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKDHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RLYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6269..7549)
                     /locus_tag="ACL73E_000005"
     CDS             complement(6269..7549)
                     /locus_tag="ACL73E_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGS0800069.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VVATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7720..9804
                     /locus_tag="ACL73E_000006"
     CDS             7720..9804
                     /locus_tag="ACL73E_000006"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGS0800070.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNPLMLFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKLGILFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTSFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLTQYQELGYLSTDHNESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(9844..11523)
                     /locus_tag="ACL73E_000007"
     CDS             complement(9844..11523)
                     /locus_tag="ACL73E_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGS0800071.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFKKWFETTRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDAALPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12278..13507
                     /gene="arcA"
                     /locus_tag="ACL73E_000008"
     CDS             12278..13507
                     /gene="arcA"
                     /locus_tag="ACL73E_000008"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGS0800072.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHDIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13565..14581
                     /gene="argF"
                     /locus_tag="ACL73E_000009"
     CDS             13565..14581
                     /gene="argF"
                     /locus_tag="ACL73E_000009"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGS0800073.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14746..15693
                     /gene="arcC"
                     /locus_tag="ACL73E_000010"
     CDS             14746..15693
                     /gene="arcC"
                     /locus_tag="ACL73E_000010"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGS0800074.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15902..17413
                     /locus_tag="ACL73E_000011"
     CDS             15902..17413
                     /locus_tag="ACL73E_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGS0800075.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17435..18766
                     /locus_tag="ACL73E_000012"
     CDS             17435..18766
                     /locus_tag="ACL73E_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGS0800076.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGTFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            18862..18969
                     /locus_tag="ACL73E_000013"
                     /pseudo
     CDS             18862..18969
                     /locus_tag="ACL73E_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(19173..19463)
                     /locus_tag="ACL73E_000014"
     CDS             complement(19173..19463)
                     /locus_tag="ACL73E_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS0800077.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19451..19702)
                     /locus_tag="ACL73E_000015"
     CDS             complement(19451..19702)
                     /locus_tag="ACL73E_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGS0800078.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20101..20985)
                     /locus_tag="ACL73E_000016"
     CDS             complement(20101..20985)
                     /locus_tag="ACL73E_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS0800079.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21130..22281)
                     /locus_tag="ACL73E_000017"
     CDS             complement(21130..22281)
                     /locus_tag="ACL73E_000017"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGS0800080.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22427..24193)
                     /locus_tag="ACL73E_000018"
     CDS             complement(22427..24193)
                     /locus_tag="ACL73E_000018"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGS0800081.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24206..24934)
                     /locus_tag="ACL73E_000019"
     CDS             complement(24206..24934)
                     /locus_tag="ACL73E_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HGS0800082.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIWCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            complement(24949..27966)
                     /locus_tag="ACL73E_000020"
     CDS             complement(24949..27966)
                     /locus_tag="ACL73E_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 98 domain-containing
                     protein"
                     /protein_id="HGS0800083.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLITKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLTKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     NSYDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            complement(27977..30193)
                     /locus_tag="ACL73E_000021"
     CDS             complement(27977..30193)
                     /locus_tag="ACL73E_000021"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGS0800084.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCVETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSRFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            complement(30215..32085)
                     /locus_tag="ACL73E_000022"
                     /pseudo
     CDS             complement(30215..32085)
                     /locus_tag="ACL73E_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
     gene            complement(32091..33410)
                     /locus_tag="ACL73E_000023"
     CDS             complement(32091..33410)
                     /locus_tag="ACL73E_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGS0800085.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDRYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            complement(33407..34246)
                     /locus_tag="ACL73E_000024"
     CDS             complement(33407..34246)
                     /locus_tag="ACL73E_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0800086.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPIDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            complement(34249..35178)
                     /locus_tag="ACL73E_000025"
     CDS             complement(34249..35178)
                     /locus_tag="ACL73E_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0800087.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            35211..35852
                     /locus_tag="ACL73E_000026"
                     /pseudo
     CDS             35211..35852
                     /locus_tag="ACL73E_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
     gene            complement(36981..38486)
                     /gene="adcA"
                     /locus_tag="ACL73E_000027"
     CDS             complement(36981..38486)
                     /gene="adcA"
                     /locus_tag="ACL73E_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGS0800088.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(38496..39302)
                     /locus_tag="ACL73E_000028"
     CDS             complement(38496..39302)
                     /locus_tag="ACL73E_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGS0800089.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(39295..39999)
                     /locus_tag="ACL73E_000029"
     CDS             complement(39295..39999)
                     /locus_tag="ACL73E_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS0800090.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNVGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(39999..40439)
                     /gene="adcR"
                     /locus_tag="ACL73E_000030"
     CDS             complement(39999..40439)
                     /gene="adcR"
                     /locus_tag="ACL73E_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGS0800091.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(40594..41862)
                     /gene="dltD"
                     /locus_tag="ACL73E_000031"
     CDS             complement(40594..41862)
                     /gene="dltD"
                     /locus_tag="ACL73E_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGS0800092.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(41855..42094)
                     /gene="dltC"
                     /locus_tag="ACL73E_000032"
     CDS             complement(41855..42094)
                     /gene="dltC"
                     /locus_tag="ACL73E_000032"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGS0800093.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(42108..43352)
                     /gene="dltB"
                     /locus_tag="ACL73E_000033"
     CDS             complement(42108..43352)
                     /gene="dltB"
                     /locus_tag="ACL73E_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGS0800094.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVIT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(43349..44899)
                     /gene="dltA"
                     /locus_tag="ACL73E_000034"
     CDS             complement(43349..44899)
                     /gene="dltA"
                     /locus_tag="ACL73E_000034"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGS0800095.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(44920..45051)
                     /locus_tag="ACL73E_000035"
     CDS             complement(44920..45051)
                     /locus_tag="ACL73E_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGS0800096.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(45282..45986)
                     /locus_tag="ACL73E_000036"
     CDS             complement(45282..45986)
                     /locus_tag="ACL73E_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS0800097.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(46056..47882)
                     /gene="glpO"
                     /locus_tag="ACL73E_000037"
     CDS             complement(46056..47882)
                     /gene="glpO"
                     /locus_tag="ACL73E_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGS0800098.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(47924..49432)
                     /gene="glpK"
                     /locus_tag="ACL73E_000038"
     CDS             complement(47924..49432)
                     /gene="glpK"
                     /locus_tag="ACL73E_000038"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGS0800099.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(49591..51018)
                     /locus_tag="ACL73E_000039"
     CDS             complement(49591..51018)
                     /locus_tag="ACL73E_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0800100.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            51183..52055
                     /gene="hslO"
                     /locus_tag="ACL73E_000040"
     CDS             51183..52055
                     /gene="hslO"
                     /locus_tag="ACL73E_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGS0800101.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            52042..53022
                     /gene="dusB"
                     /locus_tag="ACL73E_000041"
     CDS             52042..53022
                     /gene="dusB"
                     /locus_tag="ACL73E_000041"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGS0800102.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(53252..55339)
                     /gene="pspC"
                     /locus_tag="ACL73E_000042"
     CDS             complement(53252..55339)
                     /gene="pspC"
                     /locus_tag="ACL73E_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HGS0800103.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLFLGGVVHAEGVGGRN
                     TSTVTSSGQDTSKKYADEVKSHYQSILEKVRKSLEKDRHTQNVGLITKLSEIKKKYLY
                     ELEVNVLLEEKSKAELPSKAKAELDAAFEQFKKEPELTKKVAEAQKKVEEAKKKAEDQ
                     KEEDFRNYPTNTYKTIELEIAESDVKVKEAELELLKEEAKEHRDEGTIKQVEEKVKSE
                     KAEATRLEEIKTERKKAEEEAKRRADAKEQGKPKGRAKRGVPGEQATPDKKENDAKSS
                     DSSVGEETLPNPSLKPEKKVAEAQKKVEEAKKKAKDQKEEDHRNYPTITYKTLELEIA
                     ESDVEVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAEEAK
                     RKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSW
                     YYLNANGAMATGWLQNNGSWYYLNANGDMATGWLQNNGSWYYLNANGSMVTGWLQNNG
                     SWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTV
                     DSYRVNANGEWVN"
     gene            complement(55418..55945)
                     /locus_tag="ACL73E_000043"
     CDS             complement(55418..55945)
                     /locus_tag="ACL73E_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGS0800104.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(56028..57368)
                     /gene="hk06"
                     /locus_tag="ACL73E_000044"
     CDS             complement(56028..57368)
                     /gene="hk06"
                     /locus_tag="ACL73E_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGS0800105.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(57365..58018)
                     /gene="rr06"
                     /locus_tag="ACL73E_000045"
     CDS             complement(57365..58018)
                     /gene="rr06"
                     /locus_tag="ACL73E_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGS0800106.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(58279..60711)
                     /locus_tag="ACL73E_000046"
     CDS             complement(58279..60711)
                     /locus_tag="ACL73E_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGS0800107.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(60713..61171)
                     /locus_tag="ACL73E_000047"
     CDS             complement(60713..61171)
                     /locus_tag="ACL73E_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGS0800108.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(61290..62018)
                     /locus_tag="ACL73E_000048"
     CDS             complement(61290..62018)
                     /locus_tag="ACL73E_000048"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800109.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(62018..63025)
                     /locus_tag="ACL73E_000049"
     CDS             complement(62018..63025)
                     /locus_tag="ACL73E_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0800110.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(63064..63822)
                     /locus_tag="ACL73E_000050"
     CDS             complement(63064..63822)
                     /locus_tag="ACL73E_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800111.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(63785..64075)
                     /locus_tag="ACL73E_000051"
     CDS             complement(63785..64075)
                     /locus_tag="ACL73E_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGS0800112.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQGADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(64146..64248)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(64331..65677)
                     /gene="cbpD"
                     /locus_tag="ACL73E_000052"
     CDS             complement(64331..65677)
                     /gene="cbpD"
                     /locus_tag="ACL73E_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGS0800113.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGYKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(65766..66032)
                     /locus_tag="ACL73E_000053"
     CDS             complement(65766..66032)
                     /locus_tag="ACL73E_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGS0800114.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(66034..67386)
                     /gene="dnaB"
                     /locus_tag="ACL73E_000054"
     CDS             complement(66034..67386)
                     /gene="dnaB"
                     /locus_tag="ACL73E_000054"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGS0800115.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(67430..67882)
                     /gene="rplI"
                     /locus_tag="ACL73E_000055"
     CDS             complement(67430..67882)
                     /gene="rplI"
                     /locus_tag="ACL73E_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGS0800116.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(67879..69852)
                     /locus_tag="ACL73E_000056"
     CDS             complement(67879..69852)
                     /locus_tag="ACL73E_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGS0800117.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSKAGEKLTEIVLNEIKEKEKEE"
     gene            complement(69988..70536)
                     /gene="raiA"
                     /locus_tag="ACL73E_000057"
     CDS             complement(69988..70536)
                     /gene="raiA"
                     /locus_tag="ACL73E_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGS0800118.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(70616..71278)
                     /locus_tag="ACL73E_000058"
     CDS             complement(70616..71278)
                     /locus_tag="ACL73E_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGS0800119.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(71275..72573)
                     /locus_tag="ACL73E_000059"
     CDS             complement(71275..72573)
                     /locus_tag="ACL73E_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0800120.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            72629..73264
                     /locus_tag="ACL73E_000060"
     CDS             72629..73264
                     /locus_tag="ACL73E_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGS0800121.1"
                     /translation="MEFRTIKEDDQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            73549..74469
                     /gene="cysK"
                     /locus_tag="ACL73E_000061"
     CDS             73549..74469
                     /gene="cysK"
                     /locus_tag="ACL73E_000061"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGS0800122.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(74708..75073)
                     /locus_tag="ACL73E_000062"
                     /pseudo
     CDS             complement(74708..75073)
                     /locus_tag="ACL73E_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_068988785.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            75055..75363
                     /locus_tag="ACL73E_000063"
                     /pseudo
     CDS             75055..75363
                     /locus_tag="ACL73E_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(75554..75841)
                     /gene="tnpB"
                     /locus_tag="ACL73E_000064"
     CDS             complement(75554..75841)
                     /gene="tnpB"
                     /locus_tag="ACL73E_000064"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0800123.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(76087..77127)
                     /gene="tsf"
                     /locus_tag="ACL73E_000065"
     CDS             complement(76087..77127)
                     /gene="tsf"
                     /locus_tag="ACL73E_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGS0800124.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(77206..77985)
                     /gene="rpsB"
                     /locus_tag="ACL73E_000066"
     CDS             complement(77206..77985)
                     /gene="rpsB"
                     /locus_tag="ACL73E_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGS0800125.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            complement(78209..79387)
                     /gene="pcsB"
                     /locus_tag="ACL73E_000067"
     CDS             complement(78209..79387)
                     /gene="pcsB"
                     /locus_tag="ACL73E_000067"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGS0800126.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            complement(79481..79975)
                     /gene="mreD"
                     /locus_tag="ACL73E_000068"
     CDS             complement(79481..79975)
                     /gene="mreD"
                     /locus_tag="ACL73E_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGS0800127.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            complement(79975..80793)
                     /gene="mreC"
                     /locus_tag="ACL73E_000069"
     CDS             complement(79975..80793)
                     /gene="mreC"
                     /locus_tag="ACL73E_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGS0800128.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            complement(80852..81646)
                     /locus_tag="ACL73E_000070"
     CDS             complement(80852..81646)
                     /locus_tag="ACL73E_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0800129.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKSMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            complement(81639..82478)
                     /locus_tag="ACL73E_000071"
     CDS             complement(81639..82478)
                     /locus_tag="ACL73E_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGS0800130.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            complement(82463..83290)
                     /locus_tag="ACL73E_000072"
     CDS             complement(82463..83290)
                     /locus_tag="ACL73E_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGS0800131.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALDLVGMLDFKKREPARLSGGQKQRVAIAGVVVLRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSHNGYNLPENYLTESELEDKLWELL"
     gene            complement(83287..83832)
                     /gene="pgsA"
                     /locus_tag="ACL73E_000073"
     CDS             complement(83287..83832)
                     /gene="pgsA"
                     /locus_tag="ACL73E_000073"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGS0800132.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            complement(83843..84664)
                     /gene="rodZ"
                     /locus_tag="ACL73E_000074"
     CDS             complement(83843..84664)
                     /gene="rodZ"
                     /locus_tag="ACL73E_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGS0800133.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            complement(84706..85989)
                     /locus_tag="ACL73E_000075"
     CDS             complement(84706..85989)
                     /locus_tag="ACL73E_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGS0800134.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLIVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            complement(85986..87236)
                     /locus_tag="ACL73E_000076"
                     /pseudo
     CDS             complement(85986..87236)
                     /locus_tag="ACL73E_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
     gene            87395..87763
                     /gene="yaaA"
                     /locus_tag="ACL73E_000077"
     CDS             87395..87763
                     /gene="yaaA"
                     /locus_tag="ACL73E_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGS0800135.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            87766..88863
                     /gene="recF"
                     /locus_tag="ACL73E_000078"
     CDS             87766..88863
                     /gene="recF"
                     /locus_tag="ACL73E_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGS0800136.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(88914..90392)
                     /gene="guaB"
                     /locus_tag="ACL73E_000079"
     CDS             complement(88914..90392)
                     /gene="guaB"
                     /locus_tag="ACL73E_000079"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGS0800137.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(90544..91569)
                     /gene="trpS"
                     /locus_tag="ACL73E_000080"
     CDS             complement(90544..91569)
                     /gene="trpS"
                     /locus_tag="ACL73E_000080"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGS0800138.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            91775..93397
                     /locus_tag="ACL73E_000081"
     CDS             91775..93397
                     /locus_tag="ACL73E_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0800139.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            93459..96011
                     /locus_tag="ACL73E_000082"
     CDS             93459..96011
                     /locus_tag="ACL73E_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGS0800140.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFNLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(96041..97694)
                     /locus_tag="ACL73E_000083"
                     /pseudo
     CDS             complement(96041..97694)
                     /locus_tag="ACL73E_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            97822..98364
                     /locus_tag="ACL73E_000084"
     CDS             97822..98364
                     /locus_tag="ACL73E_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS0800141.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(98405..98478)
                     /locus_tag="ACL73E_000085"
     tRNA            complement(98405..98478)
                     /locus_tag="ACL73E_000085"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(98442..98444),aa:Asn,seq:gtt)
     gene            complement(98484..98555)
                     /locus_tag="ACL73E_000086"
     tRNA            complement(98484..98555)
                     /locus_tag="ACL73E_000086"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(98520..98522),aa:Glu,seq:ttc)
     gene            complement(98607..99359)
                     /gene="comE"
                     /locus_tag="ACL73E_000087"
     CDS             complement(98607..99359)
                     /gene="comE"
                     /locus_tag="ACL73E_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGS0800142.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(99356..100681)
                     /gene="comD"
                     /locus_tag="ACL73E_000088"
     CDS             complement(99356..100681)
                     /gene="comD"
                     /locus_tag="ACL73E_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGS0800143.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(100702..100827)
                     /gene="comC"
                     /locus_tag="ACL73E_000089"
     CDS             complement(100702..100827)
                     /gene="comC"
                     /locus_tag="ACL73E_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGS0800144.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(100992..101065)
                     /locus_tag="ACL73E_000090"
     tRNA            complement(100992..101065)
                     /locus_tag="ACL73E_000090"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(101029..101031),aa:Arg,seq:tct)
     gene            complement(101109..101588)
                     /gene="rlmH"
                     /locus_tag="ACL73E_000091"
     CDS             complement(101109..101588)
                     /gene="rlmH"
                     /locus_tag="ACL73E_000091"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGS0800145.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            101771..102952
                     /locus_tag="ACL73E_000092"
     CDS             101771..102952
                     /locus_tag="ACL73E_000092"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGS0800146.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            103010..103768
                     /locus_tag="ACL73E_000093"
     CDS             103010..103768
                     /locus_tag="ACL73E_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGS0800147.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEALAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            103981..105342
                     /gene="dnaA"
                     /locus_tag="ACL73E_000094"
     CDS             103981..105342
                     /gene="dnaA"
                     /locus_tag="ACL73E_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGS0800148.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            105501..106637
                     /gene="dnaN"
                     /locus_tag="ACL73E_000095"
     CDS             105501..106637
                     /gene="dnaN"
                     /locus_tag="ACL73E_000095"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGS0800149.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNITITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            106702..106896
                     /locus_tag="ACL73E_000096"
     CDS             106702..106896
                     /locus_tag="ACL73E_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGS0800150.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            106980..108095
                     /gene="ychF"
                     /locus_tag="ACL73E_000097"
     CDS             106980..108095
                     /gene="ychF"
                     /locus_tag="ACL73E_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGS0800151.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRASYHLLGLGTYFTAGEKEVRAWTFKRGMKATQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            108166..108735
                     /gene="pth"
                     /locus_tag="ACL73E_000098"
     CDS             108166..108735
                     /gene="pth"
                     /locus_tag="ACL73E_000098"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGS0800152.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            108736..112245
                     /gene="mfd"
                     /locus_tag="ACL73E_000099"
     CDS             108736..112245
                     /gene="mfd"
                     /locus_tag="ACL73E_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGS0800153.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKVPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASHPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSCLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIVENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            112303..112569
                     /locus_tag="ACL73E_000100"
     CDS             112303..112569
                     /locus_tag="ACL73E_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGS0800154.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            112562..112930
                     /locus_tag="ACL73E_000101"
     CDS             112562..112930
                     /locus_tag="ACL73E_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGS0800155.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            112935..113057
                     /locus_tag="ACL73E_000102"
     CDS             112935..113057
                     /locus_tag="ACL73E_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGS0800156.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            113050..114318
                     /locus_tag="ACL73E_000103"
     CDS             113050..114318
                     /locus_tag="ACL73E_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGS0800157.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            114315..115592
                     /gene="tilS"
                     /locus_tag="ACL73E_000104"
     CDS             114315..115592
                     /gene="tilS"
                     /locus_tag="ACL73E_000104"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGS0800158.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFKKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRNAILGISNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            115596..116138
                     /gene="hpt"
                     /locus_tag="ACL73E_000105"
     CDS             115596..116138
                     /gene="hpt"
                     /locus_tag="ACL73E_000105"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGS0800159.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            116154..118112
                     /gene="ftsH"
                     /locus_tag="ACL73E_000106"
     CDS             116154..118112
                     /gene="ftsH"
                     /locus_tag="ACL73E_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGS0800160.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT        36249 a        24634 c        20889 g        36358 t
ORIGIN      
        1 aaatactaag cctacacaca gactgattcc aattgttttt tagatttcaa ttttaccatt
       61 cttcatagtc aaaaccatca taatctggat attgttctgg cgacgttcca accgaacgta
      121 cgagataagc ttcttcgtcc tctgtctcga tttctctcag cacttggcat tcaaaacgcc
      181 attcatcacc gaagtcgaaa ataaacttaa atttttgttt gacacttagg ctatccagat
      241 agacattttc tgtgtaacgt tcttcaacat cgtcactaac aaagctaaga aagtaagaat
      301 ctgcatgact ccactcaaca ttatccatga aaaatgtgtg agcatgatca tttgcaaaat
      361 caaaactcca taaaatcaca tctgctagtt ccgctaacgt ttttgttttt ggaatctata
      421 tatgtcggta gcaacctttt ttaaatttga cggaaatgat ccaagcttct acagatgctg
      481 gcttttcagc ttctatttct tgttttacta attttaactg tagcatttga aaccagataa
      541 ttcttctgtt tcacgcgaaa caccctgcgc caagcaaggt gttcttgttt ttatactcaa
      601 tgaaaatcaa agagcaaact aggaagctag ctgcaggctg ctcaaaacac tgttttgagg
      661 ttgtagatgg aagctgacgt ggtttgaaga gattttcgaa gagtattaag tcgtataaat
      721 cgtcgacgct gtcgcaatgg tatgccactg gttggctgtt gtagctgcga aatccttgtc
      781 tgcgtagaag tcagtaaatg gtaggatttc aacttccagc tcgtcgatgc ggtcaagctg
      841 gccagccaga taaacctcga tacggctttc tgctcgtttg atgcgttgca agagtccgcc
      901 catacggatg tcaactgtat ccaaaccaaa gaccttgttt tctttcagcc attggtggct
      961 aaagagggca tggaagtctt caatttggct tctaagttct ggtaattctt gtctggcgat
     1021 ttgttgtaaa ctttctttat catccgcttg gtaggcctga cgaatgcgtc gtcccacatc
     1081 tactttgcta cttaaaatag cattcaactg ggcctgagtt tcaaagagat aagcatagtt
     1141 tccagctttt tctttaatgt tagcaagcgt ctcagcagcc tgagcgaagt gtggcttgtc
     1201 ctgttcaggt gtcatgtgtc ggtcaagtat cggacagaga acatcctgat aaaagacata
     1261 tcggttggga ttgatgccac tgagattacc tggtaggtct ggtaaaaggt tggcaaggtc
     1321 aatctgcata aaatcttcaa ccgttagacc agtattggtc ttgaaatgcg cagacaaact
     1381 atctaggtca ttgcgatagc tgagttctgc ccagatttgc aagcttggta ggatagagaa
     1441 ctgggcagtt tcaccaccat tgtctcccca acccgttacg atgacttctt taatctgatt
     1501 ggcacggcag gctttattag cctcgatagc cactagacgg ctaaaatggt tgtgaggtgt
     1561 aaagccaatc cacttccaag ctccccctgc aaatgcaagg tcatggctaa tcttgtgatg
     1621 attgcggaaa ttacggttgt atttttcctc gctatcctga taataatccc agtaaaccag
     1681 agtcacacgg tctttgagac ggtctaggta gacacgagtt tcctctggaa tttccacatc
     1741 acggtcgtac tggccatccg ctgacatgag tttgaagaac atatcactcc acatctggca
     1801 gtggaaacca tatttgtcag caatatccag cacgcgctcc aagtgttggc acatgaggag
     1861 actacgatcc acaacaccgt tcaaaatcag gtagcgtccc aaaccaacca agtgggcttc
     1921 gtccatcccg atattgacct tgcgagtctt cagtttagac aacgtggcaa acatgccatc
     1981 aatcaggtca taaacctttt cttcgccaat gagaagaatg tcctctacat cacggagctc
     2041 ctgcacttcc ttgacacccc atttgacaaa ggccgacaag tgggccaagg tctggatgca
     2101 tggtacaaag gtcatgtcaa actgttgagc ataggcttcg atttcctgca actcctctgc
     2161 tgaataagct ccacggaaat agccaaagta aggctgccct tcaatctggt aagtgtcttc
     2221 catgtaaagt tcaaaggttg agtagcccat gagagccaag acctcaatca tctgcttggc
     2281 agaagccaca ttcagcaccg catttcgaga acagtcaacc atgtaagcca aatcttcgta
     2341 agctgcttgt tcctcaatct ctactttatc agcttctgct agaactgtta ccaacaagga
     2401 taaggcacga taaagttggt gaggtttgcg gtaggtcaat tgatagtgac cttcctcacc
     2461 ctcgatagag atagaggctt ggtcagactg agtgacagcc acttccacat ctggtagaga
     2521 aatgtgacct tttaaaacct caatagcttg cgtttgtttg ggactaagtc ctgtaaatct
     2581 taccattgct tttcctcctg tagccagttg acaagggcac cgtagagatt ggcatctgcg
     2641 tgataggtgc aggtctggat aactggtgcg accgtgtatt cttcgtaggc atcgacaaag
     2701 tcttcaacag ccttcttaac accttggata aaatctggat tttgactgat agagccaccc
     2761 agactgatga catctggatc gatcagatac tggatattga gcaagccttg cgtcagattg
     2821 cggttcatgc gctcaatggc ttcttgacaa agagcattac cagctgcggc ctcttggtaa
     2881 atcttgcgac cgtcccaatc agtatgacca gatttttcaa tcacgtatcg taccatattc
     2941 ccagttgatg ctagttgcga ccagttatta agtttttcag caggggcaag ggttgtcatg
     3001 tagccaaatt ctccacccag accgtggcga cctcgatgaa gtctaccatt gataatcatg
     3061 gctccgccaa tccctgtccc aatcacgaca caggctgcat tttcaagctc tggatgagct
     3121 agtagttcac tgagtccaac gcagttggca tcattttcta aatggacagg tagctgataa
     3181 gagctaagcg cctcatacca agaaaagcca tggatgtagg gcaccgcact gaagccatca
     3241 atcacacctg tctcttgatt gaccgcacct ggaacgctca tagcaatccc actgtaatcc
     3301 tgttctgaca agcgttgatc tagccacgct agtaaatcct ccaagttttc aggcgttgaa
     3361 atacttgtct tatccagtat tttcccatca ggagtcagac tggcaaactt aatcccagtc
     3421 cctccgatat caatcgttgc aatggtcatt gtttttacca taaaaagggg cgaatcagca
     3481 gttagttctt actttttcgc ccatcctttc ttttgatgtt tactttttga aattaaattt
     3541 cttctttttt gatgaattct gtacgaatct cttgtggagc caatagtcct gaatgaactg
     3601 gatatagtcg ctcaagtaag tcaagaatgg tttgttgatg ttctgatatg cgcacatttt
     3661 cttgactcat attatagtaa cggaggacat agccttcttc attttccgcc actttaaagg
     3721 ctgttggaca aacttgcggt atgctgagaa cagaatggct caagaggcta ccagtcgcaa
     3781 ccacgcttcc ttcctgtcta gcaagctgaa ggctggtaaa cggtgtctgc aaggctttgg
     3841 cacgacgata ggctgagaag cgttcttggg cttggtggca ttcaagtgca aactcgactt
     3901 caaactcccg caagcattgt gcttctggcg ttgggaagta gccccagtca cctagctcac
     3961 ctgatgcacg caaaatggtc acggcaatgg tgttatcccc aaggatttcg tattcattca
     4021 atcccttgtt ggatacagtc accccttttt catcgtcata cagactgaca aaagcttgtt
     4081 ggtgttgagg attttcaggg ttttcccatg aagcagctgg tttgtttggt cgtgtcacca
     4141 cctcatagat actttcagaa tcattgcttg gacgcgtgtt atgagtcttg accaagagac
     4201 ggatacggtg atccttggca gtgttagtaa agcgagtctt gaagcggatt tgtggattgt
     4261 caacgaagac agtcaactca gtttccagag gaatgtttgt caattcttct gaccgtccag
     4321 cctcacgctt cataaactcg atgatacctt gttgctcttc ttctagcttt tcatccgcac
     4381 tgacaggcac ggtcaattca tgtttgagca agattttagc atagcgatct gtgttttcca
     4441 agacctcgtg gtccttaagc tctgcaaaga ttggctctgt tccttttggt tggaaataga
     4501 tatactcatt tccgatgtcc ccacggtctt caaagcggat aaagtcttca taggcttcgt
     4561 gagttgtctt atcatagact gtgatgttgt catccacact caccgttacg aatggtgtat
     4621 caatcactcc gttttggtaa ataccctcac ggtgttcttg ttctccttcc agcaattgga
     4681 aggttgtcca agaaagcggt gctaggtgaa ctggaatggt cacgcgcact tgtcgagcaa
     4741 tacgagcttg gcggaacttg tcttttggta aatcgtattc aaaattagct ccgaggtctt
     4801 cgattgtagc ctctacagga cgaccatcca agtcctccac acggtaactt ggcaagataa
     4861 gagcagccat ctttttgtag ccttctgttg ggtgcaattc cttgaaatca caagtcgcca
     4921 catcaatcac tgtgctgaca gtatcgacct tatcatgcaa gcctgtgtta atgacagtaa
     4981 agagatagtc actttgagcc ttatccgtag caattttacc cttccactcg ttgagcaaat
     5041 tacttttaac aaagtttcct acttggttga ccttggcaaa acgcgtttcc atctcgcggt
     5101 gaacttcgtc cacgctacag ccacagatac tatcatgtgg cgcattctgc aaaagtgttt
     5161 tccaagcata ggtcaactgg tccttgtggt tgtgtccacc agtgataata gtcaagggtt
     5221 ctaccacttg ctctaggagg ttgctatttt cttggaaggc ttgttttagg taaatgcggg
     5281 atgaagaagt gttggcaagt gtgtaccagc catctgtttc ctgactggtc aactcacctg
     5341 taacagttga taagagttca ggaagcgcac cttctacagc ttgaacatat tcatcaaaag
     5401 aactatgaac aaagattaca tccgggaaga gttcatttgc cacacgaatg gcttcgctca
     5461 gatttttctg tacaggctgg tggtcacagc cgttcatcat caaccattgg ttggtcgaag
     5521 cgtaggcacg cacatctgac aatttttgtt tccagaaggt caaggcctca tctttgtcaa
     5581 ctgggatttc attcccatta ctgtaccagt tagcaaagag aatacctaaa acacgactac
     5641 catccacacc ctgccagtac atttctgaaa actgggatgt aaactgctca tcttcaagga
     5701 cttggttgtc aaatccaatc ggcttcacac cacgaccaaa ggccgccacg tgaatgcctg
     5761 atttttgaag aatttgaggc gcttgtccca tatttccaaa ggtatctgga aagtagccaa
     5821 tctgggttga tttaccccat ttggcagctt cttgttgacc aatcaaggta ttgcggacat
     5881 tggcttcact ggagatcaag tagtcatcct gcaagatgta aaagggacca attttaagtt
     5941 tgccctcgtc aatgtagcgt tggaccttgt cgcgattttc agggcgaatt tgtaagtagt
     6001 cgtcaaggac aatagtttgt ccatccaagt ggaaactctt gaactcaggg tcattttcaa
     6061 agagatcaaa gagattgtca aacaattcca ccaactgcat acgatggctt tcaaaaggca
     6121 agtaccactc acggtcccag tgactatgtg agataatatg tacaacaaca ttttccatga
     6181 agtaaaacct cattctaaat ttaaatttta acgttttaaa tgtaaacttg tgattctgat
     6241 aagaatcggt tgagctaaag cgagcccctt agcgaatatc caagtaatcc aagaccaact
     6301 cacagaacat catgttagcc caggagaacc attcacgaga gtagagggtc ggatcatcta
     6361 cgtggaagct ttcgtgcatg acacctgtac caccatcgca ggcaaccagc tgatccagca
     6421 agaatttttt ctctgcctta tctcttgttg tcaatccttg gatagaaagg gcgattggcc
     6481 agatatagcg atagaaggta tgagaacttc cgagaccgct agcgtattct ccttggtaga
     6541 agtatggatt ttcagagctc aaaatggtac ggcgagtagc ttgatacact tcatcatcga
     6601 ccgaacagta gcccagatag ggcgcagcta gtagacttgg tacatttgga tcatccatga
     6661 tgctggcatt tcctaggcca tccacttcaa aagcgtaaat cttttcgccc ttgctgttgg
     6721 tggtgtaagc gtagttttcg attccttctt ggatttcatc ctgaagacgc ttggcatcag
     6781 caataacact ctggctatca gctaggttta atgctgcgaa gatttcttgc acataaccca
     6841 agactactac agcaaacata tttgacggaa tcaagtaact atactggcaa cagtcatcac
     6901 tcggacgaaa agctgaccaa gtcatacctg tcactgcaaa gtcaggtcca aagccatcat
     6961 ttaccaaggt gtcttcctta cggtccgtat ctcggacaaa acgataagga gagttcttgt
     7021 ggtcttgttc aactgtccat agatggagaa tttccttagt cgctacgaca aaaatctcat
     7081 caaactgact agtctcgcca gtctctttcc agaggagata agccaactgc aaaggatagc
     7141 aaagtgaatc cacctcatac ttgcgctccc agatccagcc gttaaggtct gtgtgatcag
     7201 tctcgtggtg ccctttccag ttctcctcaa tgttgaagga gttagcatag ggatccttga
     7261 gtaccaaggt catctgacgt ttgaccaaac ctgcaatggt ctgacgcagg agggcatctc
     7321 ttttagctac atgaaggtag ggtctgagtt gggctgtcga atctcgaagc cacatggcag
     7381 gaatatcccc agtcaagaca aaagttgaac catcttctaa gatttcaacc gtattgtcca
     7441 aggtatcggt gtagcaacgc tcgaaaacat ccacccactc tggatggtcc ttagcccgct
     7501 ctgctacttc atctagccat tctctaacaa tttctttcga ataaatcatc gtgcaattcc
     7561 ctctttcaaa caagtttcat tttcagtata tagcttttga gacagaaaat acatacacaa
     7621 atgatagtca tttttctaca aaatagttat ctttaaaact ccttttctaa aggccctctt
     7681 tttctgatat aatgtagaaa aacagctaaa ggaaagacta tgaaaccact acttgaaacc
     7741 atcgataccc gctttggtac tgctagcaag catgccttct ctcggggaaa taccctgcca
     7801 tacacaggcg tgccttttgg gatgaattat tttgtgcccc agaccagtga ccaggacgga
     7861 gcttggtttt ttgatccgca tctgcctatc tttcagggga ttcgattaac tcaccagccc
     7921 agtccttgga ttggggacta ctcttggctc cttctgacac ctgtcaccag tcaactgggt
     7981 ggagacagcc tctttcaccg ccagtcttct tatgatatag ataaagcttg cttccagcct
     8041 cactatttga agctcttttc cctgcgctat caaattgaaa cccagctcac accgacttgc
     8101 tatggtgctt ctattcgttt gaatcaaaag caaggcaaag ccctctccct ctatcttcac
     8161 gcagcagatg aactgaccgt agagcaagta gataagcgga ctctggctct cagacaagaa
     8221 ggcaaaacag agaccaataa aaatccactg atgctcttca ctgccctgca aatgaacacg
     8281 gatattcttg ctatcagcca agaagctgga gactggcgaa ttgacttagc aagtagtcaa
     8341 accgagatgc aactagccac ttctttcatc tctccttctc aagcactact taatctacct
     8401 caagaagatt ttgatagctg taaatcaagt gcccaagcgg attgggaaaa tctcctccat
     8461 cgttttgaca ttatagagat aggagaggct gaccgaacct tctttgacca ctgtctctac
     8521 agactcttcc tcttcccaca gactttttat gaggttgatg agtcagggca agccatccac
     8581 atggatctgg ctactggtac tgtcaagctt ggtatcctct ttagcaacaa tggtttctgg
     8641 gataccttcc gcaccacctt ccccctcttt gcccttatca taccggagca ctatcaacgc
     8701 tttttagaag gtttcctcaa tagctaccgc gatactagtt tccttccaaa atggctggct
     8761 ccagatgaac ggggtatgat gccaggtaca cttttagacg gtattatcgc agatagcgcc
     8821 tgcaaggaca tggcccccga cctagaagga gaactcttcc aagccatgct cgaaacagcc
     8881 agcaaagccg accctctcgg catcaatggc cgccacggac taacccaata ccaagaacta
     8941 ggctacctct ctaccgacca caacgaaagt gttagccata ctctagacta tgcctatagt
     9001 gatttttgta tcgccagctg tgccaaaaaa ctagagaaca tagaaatcgc tgaaacctac
     9061 aaggctgctt cacaaaatta ccgccagcta tttgacgctg agacaggtta catgcgagca
     9121 cgagacaatc aaggaaactt tcaccctgac ttctctcctt atagttgggg gcgagactac
     9181 gctgaatgct ctgccattca agctacttta ggcgttctcc acgacatccc tggcttaatc
     9241 caacttatgg gtggaaaaga aacctttagc aactatcttt tgaaagcctg tcaagatgct
     9301 cccctctttg aaacaacagg ctatggttac gaaattcacg aaatgagcga gatggctact
     9361 gctccttttg gacaaatagc catttccaac cagcctagtt tccacattcc ttatctcttc
     9421 cgctacagcg attaccctga ctacactgcc cttcttatca agacgctccg tcagaaagct
     9481 tttcacccaa gttgggaagc ctatcctgga gatgaagaca atggtagtct ctctgcttgg
     9541 tacatctggt cagctctcgg attttatcca acctgtccag gaaaaccaag ctatgacctc
     9601 ggaatccctc tctttgacca tctacgagtc tacctcgcta aagaagataa atggctggat
     9661 atccatacta aacaaaacca caaccatttt aactttgtca aagaatgccg actggacaaa
     9721 acactcgtat caactattca acaccaagac ctcttaaaag ctgaacaact aactttcacc
     9781 ctcagctggt taccaagtca ctaataacca aaagaacctt tgcatcgcgc aaaggttctt
     9841 cttttatgaa acttgaactt gaagttgatc cacaagctga ccatccaccg ttaggttcag
     9901 atagaaatcc aaggttttat ctcctgcgaa atacaaggtt ggtagcgtca gacttttttc
     9961 agtctcacca gcttgaaacg caagaacttg aatctcatcc tgataggcga caccatggac
    10021 acctgtcccc ggttgaatcg aaatcttagc ctctaaagag gagctacttt cactacgttc
    10081 aatcctaaaa tgaagagtct ctccctttgc cacagctagg cttttttctg caaatgctag
    10141 ttcctgaaca acttcttttt ttgataaccc aggagtttta taaagggaaa tcttggtcag
    10201 tagaggcata gattgtgctt cggtaatcat cacgcgcacc ttctgtgcct ctactagcgg
    10261 acctcgcaag aggcgcttat gaccaactgt gaagcccctg ccaaattcct gccagacacc
    10321 atccacctct acttgcacat ggaaagcagc gattcgttgc cctagcttca aatcttctct
    10381 taactcaatt acatcaaaag ttttaggaga acctaagtcg agttctaact ggatgggcaa
    10441 ggctgcatcg tttgcccaag agctggtctc aaggccgtct gtcaaatggc gacaagcaaa
    10501 gtctgcggaa agagctggac cagatacctc agctcccaga gccaaatctt ctttatagag
    10561 ctcattgcga taggtcgcaa attcataaag tcgttcaata tcctttgcat caaagagccc
    10621 agcttgattc ggcggaatat taagcaagag tggagttcct cgccctactg agtgaaagta
    10681 gatttcgacc aactcctcga gagacttagg atcctgatcc tcatggtaga accagcctgg
    10741 acggatggaa acatctgcct ctccgattga aaaaatcgtg cccgagggat ccccgtgctg
    10801 aagatagttc agctctgctt ctgttcctag tttatcagga ttcacctttt gccacagtgg
    10861 atcacctgca taccctcgtt cattgccaat ccagcggata ctggtgcctt ctgttgaaaa
    10921 aatcaagcaa tcgccctgca ggtcacgagt ggtttcaaac cattttttaa attcataatt
    10981 aaccttttgc gcaccctctc ctctggcacc atccatccaa acctcagcga acttaccagc
    11041 attcccatag ttaggatttg ataagatttc cttcaactga gccagataat aggcattgta
    11101 gtccgcttct cggtccacat gatagagggg actatgggca tcccacggtg acaggtagac
    11161 ccccatatcc atatcaaact ctgtggcagc ttgggatact tcaaggagca agtcgccctt
    11221 tcctctcctc caaggactga ccttaaccga ataatctgtg tgagctgtcg gataaaggac
    11281 aaagccatcg tggtgcttga ccaccaaaat caactttttg aagcccgttt ccttgagcac
    11341 acgaacccac tcacgcgcat ccaactgact cgggttaaag cgctcaggat cctcctgtcc
    11401 agtcccccat tcttggtcat aaaaggtatt aggaccgaag tggataaaag ctgctagttc
    11461 atctcccaga taagctagct gagtctgact tggtaacggt ccatgcggtt tgattttctt
    11521 catcgttata tatctccttc tttagcaact tctcttgttc acaaggttat ccacaggttg
    11581 tggataataa accatgatct aacagccagc tctttccaac tccaactggt aggctcagga
    11641 tttttctcct caatattccc tcttcaaaca gctctgtcat atggttctgc taacacctct
    11701 cagaatgcta ctctccataa ttattctcag gcttctttca ggtcattgtg tgaagaccat
    11761 tcactctcca gacttttcca cagattgtga ataagtgatt attctaagct atcacctcgt
    11821 cgactataac aaaaaataaa aagagggtca ataagataat tatctcttcc taaatactaa
    11881 gaaaagattc tataatttgt acaattgaac aagaaatgct tctccaaaat ctatcttcaa
    11941 aagaatgttg catcttttta tcctttcaca caaacatttc tctttataca gatccaagtg
    12001 ataaccagat gataattgga cactttttgg tcatttgtat attttttgaa aaatttttta
    12061 aaaaaatttt atatcctttt tatagaagtt tatgcatttg tatctatgta ttctatccta
    12121 tgttatgtat aataacataa aattgtgcta aacatcataa tttatattat tttccgagaa
    12181 attatagcca ttgacattac ctaggaattg cgttataaca tacatgtaag cggtacccaa
    12241 aatggtgcca agtcaaaatt tttaaggagg aaaatacatg tcttctcatc caattcaggt
    12301 cttctcagaa attgggaaac tgaaaaaagt tatgttgcac cgtccaggca aggagttaga
    12361 aaacttgttg ccggactatc ttgaaaggct tctttttgat gatattcctt tcttggaaga
    12421 tgctcaaaaa gaacatgatg catttgccca agctcttcgc gatgaaggaa ttgaggttct
    12481 ctacctagaa caactcgctg ctgaatcatt gacctctcca gaaatccgcg atcaatttat
    12541 cgaggaatac ttagacgaag ccaacatccg tgatcgtcaa accaaggttg ctattcgtga
    12601 attgcttcac gacatcaagg acaaccaaga attggttgaa aaaacaatgg ctgggattca
    12661 aaaagttgaa ttgccagaaa ttcctgacga agctaaagat ctaactgact tagttgaatc
    12721 agattatcca tttgcaattg acccgatgcc aaacctctat ttcactcgcg acccatttgc
    12781 aacaattgga aacgccgtat cgcttaacca catgtttgca gacactcgta accgtgaaac
    12841 actctacggt aagtatatct tcaaatacca cccaatctat ggcggaaaag tggatttggt
    12901 ctacaaccgt gaagaagata cgcgtatcga aggtggagac gagctagttc tttctaaaga
    12961 cgtccttgca gtaggtatct ctcaacgtac agacgcagct tctatcgaaa aacttttggt
    13021 caacatcttc aagaaaaatg ttggcttcaa gaaagttttg gcctttgaat ttgctaacaa
    13081 ccgtaaattc atgcacttgg atactgtctt cactatggta gactatgaca agttcactat
    13141 tcacccagaa atcgaaggcg accttcacgt ttactcagtt acttacgaaa acgaaaaact
    13201 taaaatcgtt gaagagaaag gtgacttagc tgaacttctt gctcaaaacc ttggtgtaga
    13261 aaaagttcat ttgattcgtt gcggtggtgg caatatcgta gcagctgcgc gtgaacaatg
    13321 gaacgacggt tctaacactt tgaccatcgc acctggtgtg gtagttgttt atgaccgcaa
    13381 taccgtgacc aataagattt tggaagaata cgggcttcgc ttgattaaga ttcgcggaag
    13441 tgaattggtt cggggccgtg gtggacctcg ttgtatgtct atgccatttg aacgtgaaga
    13501 agtgtaatcg ctgttcggca ttcgtcaata gaaaatgtaa aaaatagaaa gaggaaataa
    13561 taaaatgaca aattcagtat tccaaggacg cagcttctta gcagaaaaag actttacccg
    13621 tgcagagtta gaatacctta ttggtctttc agctcacttg aaagatttga aaaaacgcaa
    13681 tattcaacac cactaccttg ctggcaagaa tatcgctctc ctatttgaaa aaacatctac
    13741 tcgtactcgt gcagccttta caactgcggc tatcgacctt ggtgctcacc cagaatacct
    13801 cggagcaaat gatattcagt tgggtaaaaa agaatctact gaagatactg ctaaagtatt
    13861 gggacgtatg tttgacggga ttgaattccg cggattcagc caacgtatgg ttgaagaatt
    13921 ggcagaattc tcaggcgttc cagtatggaa cggtctaact gacgaatggc acccaactca
    13981 aatgctcgct gactacttga ctgttcaaga aaacttcggt cgcttggaag gcttgacatt
    14041 ggtatactgt ggtgatggac gtaacaacgt tgccaacagc ttgctcgtaa caggtgctat
    14101 ccttggtgtc aatgttcaca tcttctcacc aaaagaactc ttcccagaaa aagaaatcgt
    14161 tgaattggca gaaggatttg ctaaagaaag tggcgcacat gttctcatca ctgaagatgc
    14221 tgatgaagca gttaaagatg cagatgttct ttacacagac gtttgggtat caatgggtga
    14281 agaagacaaa ttcgcagaac gtgtagctct tcttaaacct taccaagtca atatggactt
    14341 agttaaaaaa gcaggcaatg aaaacttgat cttcctacac tgcttgccag cattccacga
    14401 tactcacact gtttatggta aagacgttgc tgaaaaattt ggtgtagaag aaatggaagt
    14461 aacagacgaa gtcttccgca gcaagtacgc tcgccacttc gatcaagcag aaaaccgtat
    14521 gcacactatc aaagctgtta tggctgctac acttggtaac ctttatattc ctaaagtata
    14581 attttagata ataaaccgtc taccaacagc tatgagggct gcgactaata gctttagtcc
    14641 ggtcctcttt tatgtaatgg taatctatta tttcttataa aatatgtgaa aaatcattaa
    14701 attgaaatct aaacgcattc tattgagtgt gataaaggag aatttatggc aaatcgtaaa
    14761 attgtagtag ctttgggagg aaatgcgatt ctttcttctg acccatcagc aaaggctcaa
    14821 caagaagctt tagttgaaac agctaagcat cttgtaaaat tgattaaaaa tggagatgat
    14881 ctgattatca ctcacggtaa tggacctcaa gttgggaatc tcttgctcca acatttggca
    14941 tcagactctg aaaagaaccc tgccttccca ctcgactcac ttgtcgctat gacagaaggt
    15001 agcatcggtt tctggttgaa aaatgctttg caaaatgctc tcttggatga aggcatcgaa
    15061 aaaaatgttg cctctgttgt aacgcaagtt gtcgtagata aaaatgatcc agcttttgtt
    15121 aacttgagta aaccaatcgg tcctttctat tcagaagaag aagcaaaagc agaagccgaa
    15181 aaaagcggag cgactttcaa ggaagatgct ggccgtggct ggcgtaaggt cgttgcctca
    15241 ccaaaacctg ttgacatcaa agaaattgaa accatccgta ctcttttaaa taatggtcaa
    15301 gtcgtcgtag ctgcaggtgg tggcggtatt cccgtcgtca aagaaaacaa tggacatttg
    15361 actggtgtcg aagcggttat tgataaagac ttcgcttccc aacgtttggc agaattggtt
    15421 gatgcagacc tcttcatcat tttgacaggt gtagattatg tatttgttaa ctacaacaag
    15481 ccaaaccagg aaaaattgga acatgtgaat gttgcccagc tggaagaata tatcaaacaa
    15541 gatcagtttg caccaggtag catgcttcca aaagtagaag cagctatcgc ttttgtcaat
    15601 ggtcgtccag aaggaaaagc agttattact tcccttgaaa atctaggcgc cttgattgaa
    15661 tctgaaagcg gaacaattat tgaaaaagga taagttgttt tactaataag atgtattcta
    15721 tttctagtat ctttatatca aattagaaat tattcttgaa aacatgtaca atatttcaaa
    15781 agatactagt tttagacttt aatatggtaa aacaaatata aatagaaagc gttttcttga
    15841 atgtttattt aagaaagtag ttggtttttt acactttgtt agacatcagg aggaaaaaca
    15901 aatgagtgaa aaagctaaaa aagggtttaa gatgccttca tcttacaccg tattattgat
    15961 aatcattgct attatggcag tgctaacttg gtttatccct gcgggggcct ttatagaagg
    16021 tatttacgag gctcagcctc aaaatccaca agggatttgg gatgtcctca tggcaccgat
    16081 tcgggctatg ctaggtactc atccagagga aggttcgctc attaaagaaa cgagcgcagc
    16141 gattgatgta gccttcttca tccttatggt tggtggtttc cttggcattg tcaacaaaac
    16201 tggtgctctt gacgtaggga ttgcctctat cgtgaagaag tataagggcc gcgaaaaaat
    16261 gttaattttg gtactgatgc ctttgtttgc cctcggtggt acaacttatg gtatggggga
    16321 agaaacaatg gccttctatc cactccttgt gccagttatg atggccgttg gttttgatag
    16381 cctgactggt gttgcaatta ttttgctcgg ttctcaaatc ggctgtttgg catctactct
    16441 gaatccattt gcgacaggta ttgcttcagc gactgcggga gttggtacag gggacggtat
    16501 cgtacttcgt ctgatcttct gggttacctt gactgctctt agtacttggt ttgtttaccg
    16561 ttatgcggat aagattcaaa aagatccgac taagtcactg gtttatagta ctcgcaaaga
    16621 agatttgaaa cactttaacg tagaagaatc ttcatctgta gaatctacac ttagcagcaa
    16681 acaaaaatca gttctcttct tatttgtgtt gacattcatc ttgatggtat tgagcttcat
    16741 tccatggaca gaccttggcg ttaccatttt tgatgacttt aatgcttggt tgactggtct
    16801 tccagttatt ggtaatattg tcggttcatc tacttctgca ctaggtactt ggtacttccc
    16861 agaaggcgca atgctctttg cctttatggg tatcctgatt ggtgttattt atggtcttaa
    16921 agaagataag attatctctt ccttcatgaa tggtgctgct gacttgctca gtgttgcctt
    16981 gattgtagcg attgctcgtg gtattcaagt tatcatgaac gacggtatga ttaccgatac
    17041 aatcctcaac tggggtaaag aaggcttgag cggtctatct tcacaagtct ttatcgttgt
    17101 aacttatatc ttctatctac ctatgtcatt cttgatccca tcttcatctg gtcttgccag
    17161 cgcaactatg ggtatcatgg ctccacttgg agaatttgta aatgtccgtc ctagcttgat
    17221 tatcactgct taccaatctg cttcaggtgt cttgaacttg attgcaccaa catctggtat
    17281 tgtgatggga gctcttgcac ttggacgtat caacattggt acttggtgga aattcatggg
    17341 caaactcgta gtcgctatta ttgtagtgac catcgccctt cttctccttg gaaccttcct
    17401 tccattccta taaaatagtg agtgaggtga ttccatgaaa atagatataa caaatcaagt
    17461 taaagatgaa tttcttatat cattaaaaac cttgatttcc tatccttcag tactcaatga
    17521 aggagaaaat ggaacacctt ttggacaagc aatccaagat gtcctagaaa aaactttaga
    17581 gatttgtcga gacataggtt tcactaccta tcttgaccct aaaggttatt acggatatgc
    17641 agaaatcggt cagggagcag agcttctggc cattctctgt catttggatg ttgttccatc
    17701 aggtgatgaa gcagattggc agacaccgcc atttgaagca actatcaaag acggctgggt
    17761 attcggacgt ggtgtccaag atgataaagg cccttcgctc gcagctctct atgcagtaaa
    17821 aagcttgctg gaccaaggta ttcagttcaa aaagcgcgta cgctttatct ttggtaccga
    17881 tgaggaaacc ctctggcgct gcatggcacg ctacaatacc atcgaagaac aggccagcat
    17941 gggctttgca cctgactcat cttttcctct gacctatgct gaaaaagggc ttctacaggt
    18001 caaacttcat ggccctggat cggatcaact agagcttgaa gtaggaggca cctttaacgt
    18061 tgtaccagac aaggccaact accaaggtcc cctctatgaa caggtttgta acgatctcaa
    18121 agaagctggt tatgattacc aatccactga acaaaccgta acggttctcg gagtgccaaa
    18181 gcatgctaag gatgctagtc aaggtatcaa tgctgtcatc cgactagcta ccattcttgc
    18241 tcctctccaa gaacaccctg ctctcagctt tcttgcaaca caagcaggtc aagacggcac
    18301 aggaagacaa atctttggtg atatagcaga tgaaccttct ggtcacctat cctttaatgt
    18361 cgcaggtctc atgatcaatc atgaacgttc tgaaatccgt attgacattc ggactcctgt
    18421 cttagctgat aaggaagaac tagtagagtt gcttacaaga tgtgcacaaa actaccaact
    18481 ccgctacgaa gagtttgact atctagcgcc tctatacgtc gcaaaagaca gtaaactcgt
    18541 tagcacactg atgcaaatct accaagaaaa gactggcgat aacagtcctg ctatttcatc
    18601 cggtggtgcc acttttgctc gcaccatgcc aaattgtgta gccttcggcg ccttattccc
    18661 aggagcgaag cagacagaac atcaggcaaa tgaatgtgcc gttctagaag atttgtaccg
    18721 tgctatggat atttatgccg aagccgtcta tcgacttgca acttaatcag gcaactgttt
    18781 ctaccaaaaa aaaatcgacc gattaatgaa ctgcacccca aaagttagac ggaataaatc
    18841 taacttttgg ggtgttttat tatgaaattg agttatgaag ataaagttca gatctatgaa
    18901 ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt ggatgtttct
    18961 ggtctaaagt catctgaatc tttgagatga gctttataaa tcgctttttt cagtttttgc
    19021 actggtgttt cgataaactc aaacttttta gccgtggtat tgcctgattt tatagtatat
    19081 tgaaactaga atagtacacc tctacttcta aaacattttt agaaatcgat ttgactgtcc
    19141 tgatcgattt gtcctgttct tatttcattt tactatattt gagccacttc gtctttaacg
    19201 gctttattca taagctcttg taatttttct ttactatcaa ttacttctga ttttccgttg
    19261 taatttattg taataggttt taacttacct aatttctcga cacgctcatt aatttgatct
    19321 tttttgaagg ctgcatatgt ttttcctaag attttttcga aaatatattt atcagatagc
    19381 ggtttgcctt cttcttcagc ttggtttttg tattgatttg aaacataagg aacaaatcct
    19441 tcatagtaac ctaatgctcc cataagttca aaagcttgtt ttctaattca aaccattgca
    19501 actcagattt cagcttttca gataaatcct gctcatccaa ataatgactt gaaattagtg
    19561 ctgaactcgt ttctgtatcc tgtacaggct gatcacccat accagcaaaa aataaactcg
    19621 ttcctagcaa gaccgaacaa gctcctattg catatttcct caaagaaaaa cgctgctttc
    19681 tctcaaattg aaattctttc atcccatctc ccatcattca ttattactgt atattttgta
    19741 tatcagaaat agtttgtatt cacaaatctt tctagttatt cccttatcat tcctaattaa
    19801 gggagataac atacaataat ttttagttaa atgtatatcg atgttttttg tttttcttaa
    19861 taaacgcaat acaaaaagag cctgttgcca agctctttgt actcaatgaa aatcaaagag
    19921 caaactagga aactagccac aggttgctca aaacaccgtt ttgaggtagt agataagact
    19981 gacgaagtca gctcaaaaca ctgttttgag gttgcagata gaactgacga agtcagtaac
    20041 atctatacgg caaggcgacg ctgacgtggt ttgaagagat tttcgaagag tattagtcta
    20101 ttatttcttc tcagcgcgaa gggctgacaa gatttgtgtt cggatatcat ccacaccatt
    20161 tggagtattt ggtaaaaaga tagtttgatt tcctttagag gcaaaggtat tcaaggtatc
    20221 caaatactgg ttggtcaaga ggatagacat gatttgttct tctgtcatgc caacattggc
    20281 ttccttgagt tcggtgatag actctgccaa tccatccaca atcgccttac gttgttgggc
    20341 aatccccaca ccatgaaggc ggtctttttc tgcttctgct tcagctgcag tgacaatttt
    20401 aatcttgtca gcttccgcca attcttgtgc tgcgacccgc ttacgttgcg ccgcattgat
    20461 ttcattcatg gattgcttaa cttctgcatc tggttcgacc ttggtaatca aggttttcac
    20521 gataatgtag ccgtaagtgg tcatttcttc tgctacttgg tgttgaacct caagggcaat
    20581 ctcatctttt ttctcaaaca attcatccaa ggttaatttt ggaacagaag agcgaagagc
    20641 atcttcgata taagatttaa tctgagattc tggacgtatg agtttatagt aagcatctgt
    20701 cacgctctgc tcgttgacac ggtactgagt cgctacattc atcataacga acacattgtc
    20761 cttggtctta gtctcaacca caatatcact ttgcaacaag cgcaactgaa tccgtgctgc
    20821 aatcgagtca atcccaaaag gcaagcgaat atgaataccg ctattagcaa ccttttggta
    20881 tttcccaaag cgttcaataa tcgccaccga ctgctgacga accacataaa ctgtactcag
    20941 tgtgactatc accaatagga gcacacaaac aatcagaaaa atcatgaaaa atattgccat
    21001 aatggaacct ccacaagtat ttttctagta ttatagcaca tttaaagaag gctgtgccgt
    21061 ttttactgcg atttttcctg aaatgtcaat aattagaggt gaattgtcct attgtcgtcc
    21121 aatctcttgc taaaataact ctttataaaa ggcaatcgtt tcttctaagg ttggcataaa
    21181 tggatttcct ggtgcgcagg catcaatcaa ggcattctta gaaaggtatt caaagtcgaa
    21241 atctttttct tcaataccaa gttcagtcag tttcttagga atacctactg tctcagaaag
    21301 cttctcaatc tcaacaatcg cataatcggc acattcttga tctgatttac cttctacatg
    21361 aagtcccaag gctttggcaa cattgcggaa agcttctggt acacgtttag cattttcacg
    21421 ttctataact ggtagcaaca tggcacagca aacaccatgt ggcaaattat atactgcacc
    21481 gagttggtga gccattgagt gaacataacc aagaccagca ttattaaagc tcataccacc
    21541 aaggaagatg gcattgacca taccttcacg cgcttcaata tcatgtccat tttctacagc
    21601 acgaggaaga tattccttga taagctcaat agcaccaata gacagtttct tggttacatc
    21661 ataagcacca ggtgttacca aagcttcaac agcgtgagtc agagcatcca taccagtagc
    21721 agcagtcagg cctttaggtt tggaaagcat gagttccggg tcattaacag agataagagc
    21781 aaggctattc ttgtcaacca ttaccatctt aaccttgcgt tcttcatcag taatcacata
    21841 gttaatggta atttctgctg atgtacctgc cgttgtattg atagccacaa ctggcaagcc
    21901 ttttttagca gacttatgaa gcccttcata atcctgtggt tttccaccat ttgtagccat
    21961 gatagaaata caactagctg catcctgtgg agaaccccca ccaagactga tgataaaatc
    22021 acagccatgt tcttgcaaag cagctacccc atctgtgaca ttcttacaag tagggtttgg
    22081 ctctacatcg ctaaagatga catattcgat tccttctgta tccagtggtt ttaaagtctt
    22141 aggtaaaata tcactgcctt cgatgtactt atctgtaacc aaaagtgcct ttttatagcc
    22201 aagttccttg atataaggac ccacttcatt tacaacacct tttccaataa ggttgactgc
    22261 cggaacataa aatgtagcca tataattttc ctcctgcgcc tccgcgctat ctatttaaca
    22321 tcattatatt actttttgta ttcgttttta attatttgtg aattgtttaa caaatctttt
    22381 taaaaggata ggagggacgt aagttcacct cctatataaa caagttttat ttatgtagtg
    22441 gtcccaacaa ctgacatgca cgatagtctg ctgattctag atcttctgtt ccaaataagg
    22501 accaattttt aggtctaaag atatcttcct caggtacatt atgcatattg acaggaattc
    22561 tcaacataga agccaaggta atcaagtctg ctccaatgtg tccatatgtt atggctccgt
    22621 gattagctcc ccaattattc atgacgtcat agacagactt gaaagcacct tttcctgtca
    22681 aacgtggagc aaaccaagta gttggccatc ctggatctgt acgattatct aaagtatggt
    22741 gaacatcttc aggaagttca agtgtataac cttctgcaat ttgtagcact ggaccaaccc
    22801 cttttagaag attgagacgt accattgtta ctggcatatc ccccttcgtc aagaaacgag
    22861 ttgagaatcc tcctccacgg aagtattcgc ggtttgctgg tgggaagtct gtattttcaa
    22921 gcatagcctg cacttcactt tcatccaact cccagaatgg tttcataaca ggtttgccat
    22981 ctcgagtagc ttgccctgta ccatccaatg tacaagaacc agagttgatt agatgtaaga
    23041 agccagctgc agcacgaccc tctaaagtat gtcccgttac acgtttaaca gcctctggac
    23101 tccaataagt gcgcacatca gcaaagattt gtggagtatt tgttaataga taattaaaga
    23161 gcatagacac accatttagt gaatcattct ctgtcgcaaa tacaaatggt tttcgaatac
    23221 cattccagtc aaactgagta ttgaggaaag tttccataaa gtccccattt gggaaatggt
    23281 ctgtccactg gcgttgacct tggaaaccag ctactaaagc atggtgacca actgcttctt
    23341 cctcaaaacc aagttcagca agtcttgggt taccaaccat taagtcacgt ccaatcatga
    23401 acatcttaat aacaaattcc cattgttttt ctttctcttc tttagaaaga atcaaatcct
    23461 cacgatttcg gtcaactcct tctttgatat gttcttttac ccaaaccata gcacgttcaa
    23521 actcttctgg gtcgtaaata ccacggtcca tacggcgcgt gaactccgtc atatctaccg
    23581 attcatttcg cattcctaag tattcttgga agaaatctgg atttacaata gaaccgccaa
    23641 tccccatcga aacactaccc attgataggt aagcagtgtc tctcatcaag ccagttgcaa
    23701 gagctgcacg cgcataacgt aaaagttttt ctttgacatc ttctggaata gctgtatcat
    23761 tagcttcctg aacatctcta ccataaatcc caaaggctgg aatccctttt tgagcatgtg
    23821 aagctagtac agctgcaaga tagacagctc ctggacgttc tgtcccatta aatccccaaa
    23881 tagcatgagg aatatctgga gacatatcca tagtttcact accataacac cagcatggtg
    23941 taactgtaat tgttgcgcaa acatttgatt ttttaaacaa ctcatgggaa gctgcagcct
    24001 ctggaacacg accaatagta gatggagaaa tcacgcattc cacaggttcc ccatctggat
    24061 atttcaatgt gcttgaaatc aaatctgcca cacttttagc catgttcatt gtttgcactt
    24121 caagtgattc gcgtacacct tgacgacgac catcaatagt cggacgaata ccaatacgtg
    24181 gatgttgaat catactattt tcctcttatt tttctgtttc tttcatacta ccatcgccat
    24241 tatatttacg gtagcctggg tgacgacctg taaccttata attttctcgc attgagaata
    24301 gacgttctaa agtcggacga gcaatttctt gctcctcaat gccctttgta gaaagtaaca
    24361 ttcttccgtg gaaggttgtc tttgcgacta attctaaagt ttccatacgg tagtatgctg
    24421 taattacatc gcttccgaca gtcagagctc catgattttc taatagcatg acatcatgat
    24481 cgggcagata aggtgtaatt gcttctggca cttccattgt agacggaact ccaaatggcg
    24541 ttataggaat tgcccctacc acaatcgcgc tctcaattag tgaataagta tctaaaggaa
    24601 tgtgtgcaag agcaaatcct gttgcaatcg gtggatgcgc gtgaacaact gaacggacat
    24661 cctcacgttc ttcgtagcac caaatgtgca ttttaatttc actagaagga cagtaatcac
    24721 cttctgcttc taaaatctct cctttaagat ttaacttcac cagcttttct ggtgtaataa
    24781 aacttttgct gataccagta ggtgttgcaa gaatggtatc ctcatctaat cgaacagata
    24841 cattcccatc gttagcagca acccaaccaa gttgccacat cttatgacaa acatcacaaa
    24901 tctgttcacg aattaatttt tcatcttgag acataaactc actcctttct aaaaatgaag
    24961 ttcgaattca agatttccgt tactgttaat ggtaatagta accatatgat ttttctgatc
    25021 aaaattgaga gatggctgat cataggaatt atttgttcct gataatgaat gaatagtagg
    25081 aagtttatct atacctctta atactatctt tgtaaccctt ttctctccaa actgagtatc
    25141 tttgatataa tgttcttcaa tccacttaat cgcacctttc ttggtcaatt gtggtagttt
    25201 ctttgcctga tttgcatctt gagcattaga ccatagtgaa tctttatttg ttctaaaatt
    25261 atttaaattc actttcaatc cattacttat tctctcaaaa ataccatagg tatgaggttc
    25321 aaattcaaca tccatttcta aagaattaaa ttttaatttc ccagtctgtt taacattctc
    25381 atttaccttg taattataga caaaccatct attatctaat ttctgagcaa agatatctcc
    25441 ttcataattc ataggataca gcttatttaa gtattctttt ctagcctgag tagagctaaa
    25501 ttctggagaa gtgatttcct taatctgaat acggctacca gaaacagact ctttcaattt
    25561 atctgttttt aaaacacctg gaatagctgg aataacatta taacgaccag tcatgtataa
    25621 tggagtttgt tctctatcag tatttacgtt tacaaagaac ttaccatttc ctttatttga
    25681 atagtctcca tgtatgaata cttttgtatc ctcaagtacc ttttctttgg atggtgctgg
    25741 atgcgctatt acatatctaa aaaattcttt tattacttcg ctaaagagta agctttcttt
    25801 attatttaca ccataggtat aagctgggtg ttcaaaatta taaactacac ctccattaag
    25861 gtaaacccct aaagcttctt ctcctagcat agactctggt tcagtcaacc attgtctatc
    25921 tccttgactt tttccgatat taccacttgc aaacagtttc catttacctg tctcatacca
    25981 cttccaagta tccatcaaac caccccattg ataagtatga tttgaaagcc aaagtccctt
    26041 catataactt tctgtagttg aatcatttcc ctcagcagca ggtgtatttt tgaacatgaa
    26101 aataaggttc ttccagtact tatcaacaga tttctgaaat gctatcttac cgttttttcc
    26161 aaatgctttt tctattgcag aaccattatt ttgttcagcc catataaaat atcctccatt
    26221 tttagctgat acttttaagt aatctgccgc cttattttca atatcatttg cccaaatcca
    26281 ataattctct gtactgaaaa taccatgcaa atttggatat ttttgataca ttttatcaat
    26341 ccagctggta cttaaccaat gtgccgaagt ataataaggc atattaccag cagtgtaaac
    26401 cgtcagaata actggaattg gttcattttt tccagtctta ggatttacat atttcgctgc
    26461 ttcttctaac atatgttcat aaaaatctct agcagctcca tctcttttag taagatcatc
    26521 tggatgtaac tgtataacag tatatggttt taagtcatct ggtatattct cccacttacc
    26581 tgttaatgta tctcctcccc aaaaagtata tttcccttgg ttaaactctt ctccgttagc
    26641 atataaaggc atcataagta acggatgttc attattaatt tcacgacgtt tatcaacttc
    26701 tgaccaatca ttaggattct taaatttacc atttgccata aacaaggctc cacctaaaac
    26761 caattcgtca gcccatgtat gtttccctga atatgattta agttctattg tctgtgtatc
    26821 tttgggaatt tcaacatcaa ccagaaatgc cgatgtatca tacttaattc cttttggata
    26881 ttttgaatct gatgagtaaa tgactttacc atccgcaaca acttcaaatt tttgaatatc
    26941 tgcgtaatct gaatttaaat gattggcgct cctatcaatt ccgacatagg aaataaatct
    27001 tgtaacatta gcacccgaaa catcatattt tatactagac gggttgcttg ctacagttcc
    27061 caatccctta ttaaattcga cttccttacc gtcaattagt aattttattt tattattaga
    27121 cccgttatta ccaggtgtaa acggtttatc tttctgaact gtttttgatt tatcgtcatc
    27181 accatgagta gcatcaaccc attctaaatc agaaagatat actcctccat taattccttt
    27241 attaagaaga tctggagtta tagtttgagt actaacagtt ttaataagtt tagcatcagc
    27301 aaatacaacc tcatcacccc atgtatgttc tcctgcgaat gattttaagg atattttttt
    27361 agcgttttgt ggaattgtca cactaataaa ttgtgcctgg gtattatatc tgaatccttc
    27421 tggattagtt acactactag aatagacaac ctttccatca atttctattt ctattctatc
    27481 cactactgca tggtctgatc tagaactatt agcactttga tcaattccta tataagtttc
    27541 aaatttttca aacccttgac cgctgatatc atagctgatt actgatggag aatctgcgac
    27601 tgttcctatt cctttatcaa aatatttaac tttatcatca gaagtgagca atgaaatctt
    27661 agtatgctct cctttatttc ctgttgtaaa tggagcatct ttttgtactg tttttgtttt
    27721 atctatatca ccatgagttg cagaagacca atccatatct gaaagatatg tcatctcttt
    27781 atcaatttct ttatctttag taataagttt ttctaagtta ttccctgtta ctctagcagt
    27841 ttcagtacta gctctgttat tagaattact ttgaactaca tctgcataaa ccaaattact
    27901 tcctaaaaaa cttgttaaaa cagccgtagc tattaaaatc tgttttgcta tttttttact
    27961 ttccattttt atttcctcaa tatttacata caacttcttc aataacaaat aattttgtaa
    28021 gatattctgg aacacaaagt gctaaattac ttaaactgac ttttattcca gcattcatta
    28081 attcatctcc ataaaagaac tcatcaaatc tagagacgga atagcattta tctttatcta
    28141 aaccactaaa ataaactctt gtataacctg gattcaactt actattcaat tgagcataca
    28201 ataaaatcga ttggcattta tcttttgaaa caacttgcca actagcagaa tcacaactaa
    28261 aaggactgtt tatcctatag aaatccccat attgaaacaa tgaacgatat tttttataaa
    28321 actgaatttg ttctctcact tgttcttttt cttctaccga caatctcgta acatctaatt
    28381 cataaccgaa agaactaaaa taagctacat ttgtcctagt gtccaaactc gtttgtcttc
    28441 cactttgttc atttggagaa atagaaacat gggctgtcat cattgatgga gaatatccat
    28501 aagaagttcc atgctgaatt ttcaatcttt ctatcgggtc cgtatcatca ctcgtccacg
    28561 cttgcggtgc ataatacata agtcctaaat caaaacgtcc accacctgaa gaacaagatt
    28621 caaatagaac tgaagggaac ttagttatta aacgatctaa taactgataa agacctaaga
    28681 tatatcgatg accaaattcc atctgctgtt cagaatcaag ttcaatacta taaatatctg
    28741 ttatatgacg attcatatcc catttgatat aatccagatt tgttttgatt atgattttag
    28801 aaatagaatc aaaaaggtaa tcaacaactt cctgtctcgt caaatccaac acatattgat
    28861 ttcttcctac tgacttctct ctgtctaaca aatggatagt ccaatcggca tgattcttgt
    28921 acaaatcact atcaatagaa atcatttcag gctcaaacca caaaccaaat tgtaaaccta
    28981 ttttgtgaat ttcatctgca agaaatccaa taccttcagg aaggcgactt ctatctgtta
    29041 cccaatcacc cagagaactt ttgtcatctt tcctatgacc aaaccaacca tcatccagta
    29101 caaataattc tatccctaaa tctttagcag cctttgctaa atctaaaatt ttttctgtac
    29161 tcaagtcaaa ataaaatgtt tcccaactat tgagtattat aggacgacta gcttgagaaa
    29221 aattaggatt aactaaatga tgtcgataaa aatctgatag ttgttggctc atctgattca
    29281 tcccttgatc agaatagatc acaattgctt ctggtgtcac aaaactttcg gcaggattta
    29341 ataaaaaacg aaattctact ggatttattc ctaccgttac tctagcggtg tcaaaatggt
    29401 caacttcaat catattttga aaatttccag aatagataaa gttaaaacca taaacctcac
    29461 cactatgctc tgtagtttcc ctccttgata gcataaagaa aggattttgc tgaggacttg
    29521 atgagtatct caagctatct attgcttgaa tacctggtct aagcgaagtt ctatataact
    29581 gacgttccct cagccatgct ccagaaaatt gaataaagtc atattgacta tcaggtagat
    29641 ctagctgtaa gctcattgct ttcaaaagag tcaacttatt attgctatta tttaaaaatt
    29701 ccgtatttct aactaagaca ttgtattccg gaaaaattgt gtaatttagt ctaacagtta
    29761 aatctaatat ggaatctgtt aaaataatcg ttaatgtttc cacacactga ccaatatcat
    29821 caaatgttga aggtagagag ttaagacgat ttttcccttt ttcaagttca aaaccttgat
    29881 attttagtgt cgttatccta ctaccattca ttccttgaac ttgaaaggct ggatgccgaa
    29941 aatctccttt cccatatgaa gaatattcat tttgtatcat agactgttga atatcctcaa
    30001 attcttcaga aaaagatact tcaaatcctc ttttttcata agccatcaat tggttataat
    30061 tttccttgac atgaatcctt ttcccaaaat gtagatgttg aagttcccca ttttctaaaa
    30121 ttctaaaaat ataactacta tctttcattg ccaaatgaaa aacggtctcg tccttattaa
    30181 tataaatcgt catctctacc tcacaatttt ttctttactt cttcagtatc acgatagagt
    30241 acggtgccaa ttctatctca tcttcttgaa tagtaaaatc tccaattact ctggtaaaat
    30301 tctctatcga aagattctct atttttattt tttgtttaat ctgagcagga tttctcagag
    30361 agagaatttc agtagaagtc ttctgattgt gacacttata accataaatt tcaaattttt
    30421 caggacttcc tcctattttt ttactatatt ttagtgtttg ataattctcc tctatccatt
    30481 tgacggcacg agcattggct ttccagcgtt cttcatcaaa catatcaaaa gaatagtgaa
    30541 actcccaaaa agcattccct cttgttgaaa taaataatag ataagcttca aaatctggta
    30601 ttgatgcaaa catttgatga tccatgtacc aggtatttgc actgacagca tagattggtt
    30661 catgattata aatcgaccac ataggtaact gtatctcacg tttttccaaa aattcttgat
    30721 actgaatatc tcggtaagta atcatacgat tgatatcatt acctgcattc tctgtaaagc
    30781 ctacatcttg agatatttga atccataaac tattgaccca ctgtaaaaac catggactag
    30841 gatttacata agaagtcaag tttaaccaac aatcttttcc tcctctctcc tttcttagat
    30901 ctatcaacag ttgaattaag aactcataaa ccgctgtcat ggtatacata ccgtgcggtc
    30961 cactcttatc aggtttgtca ggttgaagta accaaccatc aattttccaa tagctgatat
    31021 cgaattcttt ttgatattcc aacatctttt tcttcatttg attgagatag ttaaaatcag
    31081 ccacgtttac atcatttgaa atcaaatttt tagatccaat atttaactct ggatgtgctt
    31141 ctaaccaatc actcataatg atttctgtcc cattgtaacc acctcgggga ccaatccaca
    31201 atcctaggct tgaaccaaat ccatttacaa gatatttaat atttctcaaa ccatttggga
    31261 atttatgatt gaattcccaa actgattgat agtttgtcca accatcatca acaacataag
    31321 catctaaatg aactccatga ttttcaaatc catctcgaat ctcagaaaaa ctttttaaaa
    31381 taccttcctc tgtaatatcg gtcatatggt cataccagga attatactgt ttacggaaat
    31441 aactaggttg agctattcct tcaacatatt caaaaaatgc ctcttgaatc tcttcttttt
    31501 tataagaaca tgctccccca ataatacaag accacaaact cttttcttga tttacaacag
    31561 ttcccaagta atatcttgat acatagtgtc taccatctac cttgttttca gacattggaa
    31621 attccattcc taagaataaa gaattcgcat aaacaggttg tcccaattct acataataac
    31681 cggaaaaatt cgccatttcc ttaatacaat cttgtctttt cggatagaaa atattgtctt
    31741 ctgtttcaaa ctcaaaactc tctacctcta cagatttaat aacctcagta gatgattcta
    31801 aaactaattg cttcgaaaga acatcatccc tcgattcaaa gattaaacgt aaacgaatgg
    31861 aaggacaaac aaaagaaacc tgaattcgcg tatctccctc ttccctaacg attgctgaaa
    31921 aatgatttga agaaagtctt ataccattct ccaatgtaat ggtaaattct tctttcgaaa
    31981 catttttatc attactcctg cccgtttgtt tacgatatca gtagtataaa atcgaccatc
    32041 tccccaaaag aaattacgtc ttacattttt attttcaatt ttcatataaa ctactctctc
    32101 aactcaattt tgattacgct atcaatcaag tctggtaatg gataggtaaa atgtggaact
    32161 tctccaaact gtgcaaaaca aattcctttg taggcattgg tcgtccagct ttctgaaatt
    32221 ttcacctcac ttccatcatg aagaaagctc attcttttta cgttttcttt actaatacca
    32281 agaagagcta aaggacctat aggttgttca aatacatgag cataaaccgt atttccatta
    32341 cgagtatagt atccccaatc tggttttggt aaattttcat ctccactaca tccataaatt
    32401 gcctcaccat ttcgagacat ccatcgatga aaattatcta atattttctt acttgaatca
    32461 ttaattcttc ccaaagcatc tgggcctaca ttaagaatca tatttccgtt tttactaaca
    32521 cattccacta actttcttat caaagtttga ctagacttat atagataatc tgtaggatta
    32581 taagcccaat tgttattcat agttagacaa agttcccaag gaacaggttc acctttaaag
    32641 tttcgaatac cttcgtgagg aacaatttgc tctggactaa caaaatctcc agcgtaagag
    32701 gtaatttcat ctgtaacgat acttccgaat ccttcacctg atgtttctaa tctattatct
    32761 acgataacgt ttggctgata atgacgaacc atgtctatta attttgaagc tccccatttt
    32821 tcacccacca tgtcttcata agaataatca aaccataata tgtcaatctg accataacca
    32881 gttacaattt ctttaacttg attgtgcaaa tactccaaat aacggtcaaa gttaattttc
    32941 tcatctcgat aggcttcatt tcctctcatt ggatgattta gatcagcata tttagggaaa
    33001 tcaggatggt gccagtcaat caaactaaaa tataagccta cttttaaacc ttcagctcga
    33061 acagcatcta caaattcttt aactaaatct ctacctgcag gtgtatttgt tgctttataa
    33121 tctgtaaatt ttgaatcaaa caaacaaaac ccatcatgat gtttagccgt taaaaccata
    33181 tacttcatcc ctgcagcttt tgcttgttta gcccattctc tagggttata ttccttagga
    33241 tcaaaagctc gaaaatatgg ttcataatct tcaatagata atttctgatg actacgaatc
    33301 cattcccctt ttcctggaat agaatataac ccccaatgaa tgaacatccc aaatcttgct
    33361 tctctaaacc actgagttct actattgata gtttcaagtg tatgtttcat ccttttactg
    33421 ctcctcctcc taaagcttca atgaagtatt tacttgtaaa tgcgaataga atgattggtg
    33481 gtaatacgat tacaacaata gctgaaaata gaccattata attagtatta aaacttgtag
    33541 taaattgacc tagtaatgct ggtactgtta attcattttt atcaatcacc aacatagatg
    33601 cccaataata ttcattccag ttattaataa aggcaagtac tgctgctgtt aaaattcctg
    33661 gtctagcaat tggcaacatc actttccaaa aagtttgagc atatgtcgca ccatcaatct
    33721 ctgctgcctc ctccaattct tttggaataa tttcaaaata gttctttata ataaagaaac
    33781 tcatagcaat tccactacaa gagtagacca gaattagagc aactggggta ttataaatcc
    33841 ccaactcatt tactaatcta taaactggaa aagtcatagc tgttgctgga ataaatagag
    33901 tagaatacag catagaagtc accaacttct tccctctaaa ttccatccta gcaataacat
    33961 atgaagacat ggagatcata acaatgctaa taataactga tatagacact actttaaagc
    34021 tattccaaaa gtaagtaaaa acatgaagtt ttgtaaaaac atttatataa ccttcaagag
    34081 taaagtcaat cggtaaacta atacctggat ttttcatagg atctgctttt aatgatgata
    34141 aaaaaatcca cgcaataggg aaaatagaaa ttaaaatggt aaggagcata taaccatata
    34201 taagaacttt gcctttttta ctaataccat ttatatgtgt attcataatc atttcccacc
    34261 tttcagtctt tttctttctc tgaataaaat attaatacaa acgataatca acattccacc
    34321 taagatttgt ataactccaa ttgtatttgc acgagcatat tgagttcgtg agctagccac
    34381 tgctaattct cgaataacaa aactgatact ttttgttcct gcagcaccat ttgtcaaaaa
    34441 gaatacttcg ttatagagca aaaatcctga agttgctgcc ataattgaaa cagttttaat
    34501 tgtcccctta atcatcggaa tcgtaatata ccactctttc ctccaaccag taatattgtc
    34561 taaaatagca gcttcttgaa cttcttctgg aatagcaaaa atttgcccaa gaatcataat
    34621 ggttgatgct cctgcaaaga agatataagc gccagtcata gctactatat ttaatcctgg
    34681 agtcaacagt actgaatctt taaacgatgg attaaataga tgaataattt ggttaacaac
    34741 accatagttt ggattataga tttgaagaaa aatcaagccc atagcagcac tagaaatgat
    34801 acttggtaca atataaagat tcctagatat cttccagcct tttaatttct tagataatgt
    34861 aattgcaaca gatacagcta aaggaacttg aataataaca ccaattacag cccaacgaac
    34921 agaattaatt agagcttctg taaaaaatgg gtattcttta aaaacatacc tataattttc
    34981 aaataattta tcaaatccaa gaaactcagg ggtgtttaaa tttgtataat cccatttagc
    35041 aaatgaagtt aaaaagattg ttactacaga ataaaaataa aatagaaaga aacaaatcaa
    35101 cgttggcaaa agaaataaaa agataaatcg tcttttttga ttcttcctat tttgtaggct
    35161 cataattttt tgtgccataa acaaactcct tttttcaact atataagtaa aatcaaggtc
    35221 ttatcaaaag aaagcacgga tacgtgaccc tgtcctctat gaacacaatt gaactttctc
    35281 atcaaatacg ggaaggagaa agtactaggc aaaaaagact aatcgctagt ctcgctaaag
    35341 actttattcg gtctggtatg tgtatctatc tggattccag tactactgtc tacgaactct
    35401 gtccctatct ttctgaactt gataatttga ttatttttac aaatggttta catactgcac
    35461 aaaccctatc tgaaactgtt aaagatagct ccaaaatctt tatcacatct ggcgaggtca
    35521 aacatcaatc ctgttccgtg gtcaactatg ataaggaaaa ttctttatta gatcatttta
    35581 atatcgattt agcattttgt tcagcaagag gtattgatga ccaatatgtt tatgaagctt
    35641 ctctcagcca agctatttca aaaaagaata ttattgacaa agcccatgaa accatcttac
    35701 tgattgatag ttctaaattt tacaagactg gattttttaa aattaatccc ctctccaaat
    35761 acacaacctt tatttctgac accgtgccag accaaaaatt attagacgca gtcgaattat
    35821 ttgatggaga atgggtttct gatattcaat gaaaatcaaa taggaagcta gtctcagctt
    35881 gctcacagta cagatttgaa aactgatcaa gtcaagtccc ccatggacac ggcaagacga
    35941 agctgacatg atgtgaagag attttcgaag agtattcgtt ctgtctgctg actgatttac
    36001 aaatattcac cacatgacat tattttctta gcaattctaa aaacagaggc tggacaaaaa
    36061 ctcaatttca ggagaaaatg gagtaaacct tcccacaata aaacgcatag tatcaagttt
    36121 ttgcacacct gatattatgc gtttttctga ttttaaagac tttgtcgcct agaccctata
    36181 tttcaagaat taagtgacct tgatgatcta aatatattgt ggtatactat ttttgtcatc
    36241 ggttaccgat tacgttccta tgggtttgtg agaggaggtg aaactaatga gccttatcat
    36301 agagctcgct cttactatta tagcggatgt tatagctgga attatcttgt atttcgtctg
    36361 cagatggcta gatagtaagg agtagaccga ctgactagcc tataaacacc cgttaaatcg
    36421 ctaagatacg tcaaaaaagc ccttaactac ggccatagtt aggggctttg gtgttctaat
    36481 gaaccttatc aattaactac attttagcat ataatctaca atagttcaag cattaagtga
    36541 ggttgatgat ctaaatttag tgtgatataa tacttttgtc atcggttacc gattacgttc
    36601 ctatgggttc gtgagaggag gtgaaactaa tgagccttat accagagctt gctcttacta
    36661 ttatagcaga tgttatagct ggaattatct tgtatttcgt ctgcaaatgg ctagatggta
    36721 agaagtagac cgaatgacta gcctataaac acccgttaaa tcgctaagat acgtcaaaaa
    36781 agcccttaac tatggcacta gttaggggct ttggtgttct aacgaacctt atacactaac
    36841 tacattctag catataagcc cagatatttc aagagtttta tttatttttt caggttccct
    36901 tagttctgaa aggtctataa tgaagttagc catctagtat caaaaaaccg actagctctt
    36961 atgaactagt cgatttctca tcaatgcgcc aacatttctt gggcgatttc ttggccagat
    37021 aggttatctg ggtagtaggt tggccagttg tccatttctt caaagagggc ttcttggctt
    37081 gtgcctccaa agaagatatg gaaatgttct gccttaactg gggcaacatt gtggtcacta
    37141 aactgaacat acttgaattg tccagcgtca gcatctgtgg cttcaaagag gaaacgcacg
    37201 ccacgattgc ctttcttgta agtcaaaatt ttcttaccga catacttgta agtgtatttc
    37261 ttgctttgtc caccttgaac aaattccata gtattatcag taatgttaat cttagtcaca
    37321 tctgtctgat agccttttgt atagtaagcc ttgtactcag cctgggtcat cttaccagtt
    37381 aacttagcct tgtagtcaaa gacttggtca aacgtgccgt cttcaaggaa aggataaact
    37441 gattgccagt tacctgcata gtcactcaag gtacggtcct tgacagctgc atcctcgaag
    37501 taaccatttt ggactgtctt ggtatcctct gccttttcag gttcgattgc tgggccttct
    37561 tggtctgttg tttgtttcaa agccttgagg tttttctcca tcacggaaat gtagttttct
    37621 ccagccttgg tgtcctcttc tgtcagactt tctaaaggat tgaggacatc agttttgaca
    37681 cctgcttctt ttgaaagtgt gttagcaagg gcttgtgagg cattttcttc aaaatagata
    37741 taggcgattt tatttttctt gacatactct gtcaattctg ccaagcgagc agctgatggc
    37801 tctgcatctg gagaaagtcc tgagattgcg acttgtttga gtccatagtc caaggcaaga
    37861 tagttaaagg ctgcgtgttg agtcacaaag ctcttttgtt ttgcttgaga caagccttct
    37921 gcgtaagcct tatccaaggc ttgcaatttt tcgatatagg cagctgcatt cttctcaaag
    37981 gtctcttttt tatcaggata atctgctgac aagctgtcgc ggatgtgctc tactagttta
    38041 atggcacgaa ctggtgataa ccaaacatgg gggtcaaact catggtgatg accttcttct
    38101 ccatggtcat gatctccctc ttcttcctcg ccacctggca agagcaacat atcgcctgtc
    38161 gccttgatgg ttttcacttt tttcttatcc aaggtatcta gcaatttagg tacccatgtt
    38221 tccatgtttt cattttcata aacaaaggta tctgcatctt ggattttggc aactgccttg
    38281 gcagatggtt cgtattcatg aggttctgtc ccagcaccga ttaggagttc tacattagcc
    38341 gtatctcctg cgacttgctt ggtaaattca tagacagggt aaaaggttgt cacgatattg
    38401 agtttaccat ctgcctgttt ttgattggaa caagccacta aaaacaaggc acatagactg
    38461 gctagtaata agctaatttt tttcacgttc gtctcctatt tgataaaacg tcttactaaa
    38521 ctgattagta taaagacagt tacaaaaata atggtaatac ttgcacttgc aggtgtttct
    38581 gcatagtagg aaatgtaaag tcctgctacc attcccaaaa agccaatcgc actggcaagc
    38641 agcataaccg atttaaagtt tttccccaga cgcagggcaa tactagctgg caagaccata
    38701 atggtcgata ccagaagagc tcctgctgca ggaatcataa gggcaatagc cacccctgtc
    38761 accatgttaa aaagaatgga catggtacga actggcaagc catccacaaa ggccgtatct
    38821 tcgtcaaaag ttaagatata cataggacga agaaagagaa aggtcaaaat caaaacaacc
    38881 gccgcaatga caaagaggga aatgacctgt tcttcactga tagtcacgat cgaaccaaag
    38941 agatattggt ccaaactcat tgaactcgag cttttaccct tgctcatgac aatcagagaa
    39001 acagccagac ctgttgacat gaggatagct gtcccgattt ccataaagct cttgtaaacc
    39061 gtacggagat actccagaaa gaccgccgca atcaagacaa tggcaatagt agaaacagtt
    39121 ggagaaatcc ccaaaaccag accaaaggct acacctgaaa gtgagacgtg gctaagggta
    39181 tcactcatca aactctgacg acgcaagatg aggaaggttc ccaataccgg tgagaaaaga
    39241 ctcatagcaa taaccgccaa aaaggcgcgc tgtataaagt cgtaagataa taaactaagc
    39301 atggcccacc tcctggccat tctcatgaac gttgaaacaa cgccatggcg agtcttggtt
    39361 acggactaga tgaatattgc gatccgcata atccttaact tcttcagggt catgggtaat
    39421 catcaaaaca gccttgccat gatgatgggc gctgtggtgc atgagttcgt aaaattcatt
    39481 tttacttcct gcatccatcc ccgttgttgg ctcgtctagg ataaacacat cagggtcaga
    39541 agcaaacata cgcgcaatca ccgctcgctg cttttgtccc ccagatagag accccaagcg
    39601 tttgtctcga tgttcccaca tgccaactga gtccagactg gccttgatat gctcctcatc
    39661 atgagcattc aaacgacgga accagccttt tctcggatag cgacccgact tgacaaattc
    39721 atagaccgta cttggaaaac caacattaaa actggcaatt tgttgaggaa gataggctat
    39781 tctcaatttc ttaccttgcg tatttgtctt tgaaatagcc acctttccaa tgcgtggttg
    39841 cagaattcca agactagcct tgatgagcgt cgtcttagcc gctccatttt ccccagtcaa
    39901 ggtaacaaat tccccactat caacactata attgatatgt tcaagaacag gctccttatc
    39961 ataatagaag gacaaatcct ctaccgtaat atatctcatt atttgatttc tcctactaaa
    40021 gcagtcaaaa accgctgaat cactttttgt tcatttggag taaactgagt cgccacttgt
    40081 tcataggtta aaagtgtatg ctcatggtga tggtggtgct cctcagcgat tggacgagcc
    40141 aagtcagtca actgataaaa aatcacacgc gcatctttag aatctttaga tgtttccaac
    40201 atcccttcct tgaccaaaga cttaatggcc ttggtaactg ccgcctgact gacattgaga
    40261 cgacgggcca attctgaatt tgttaaagat tcctctgaca agagcataag gatatgctcc
    40321 tgagtattgg tcagggccac ctcgctagtg caatgaccta ttaggatttc atgctgattt
    40381 tccgcctgca aaatcacctc attcaaaaaa gcattgatat cctttgctag ctgtctcata
    40441 tctgactcct ttccttttag acttctcttt tttaagagaa aaatactatt ctttgacatt
    40501 ttgtttacca gttaattata tcacaagcaa aaaaagagtc aagaaaaaac gtgaaaacta
    40561 gtttcattct tgaactcttc tatattatat tatctattga aattctttga catctccatc
    40621 ataagtcgcc caatctttgc tgaaaaagcg ctcattcaga tggtaagtcg gagctggtgt
    40681 gggattggat aggaaaggat caactgcctt gtcaaaagcc aaccaaccca accagccaag
    40741 gtgaatggtg tccttcataa agaaaggctc cccgccgtcc ttagaaaaat ctgctatatt
    40801 ggtaaaacct tgactttcta actggtagcg aatcttctgc accgtttgtt gatacatatc
    40861 ctctcgtaga ccagcatagt ccatccattt tttattaaca ggtggaatga taaaaatcgg
    40921 gtttacctta gatttagaaa actgtgttaa aaccaactgc aagtcattat actctggcga
    40981 cttgagatag gtaaagcttt tctgagaatc ctttaatttc ttcaaatcct tcttgatctg
    41041 ctcattatag aaataatttt ccattcccat ctcattattg gaagtatttt tttcagcatc
    41101 tgctttgaca acatcttcta ttgcttgata agaaaactgg tctggcaaga tttttaaata
    41161 cttagctaca tgcttatcgt agttaacata gcctctaacc gaaaactgac caaaaaagga
    41221 ggcttggcgt tcattaaaac gagccaataa ttcaatcatt tcattgtctg ctgtcgacaa
    41281 ttcttcttta cttgccaact tctgaaccag gtccttcata gctacgtttg ggaactgttg
    41341 cagtaagcga gtcgctgcat attgactagc ctgatcccca gattgatgtt tcagaaaact
    41401 agtcaactgg tctccattaa aatactgctg gaaggctgct ggatcatagc catttttact
    41461 gaaccactga ggtgagataa catacacaac ttgtttattc tccagctgtg gtaacatctg
    41521 ttgcattcca aaatattggt taagcgatgc agctcccccc tgtcctaaaa gataaggacg
    41581 gtaggaacga ttgtatttct cagctaatac cgcaggatga gcaccgtcaa aacgaagcca
    41641 ttcactagag ccaaagaagg gaacaaaacg cacatttgga tcagatagtg ctctgacttt
    41701 ttgacttcgc tccttaaaac tatcgatagt agtagccact gctgaacgct tttcagctcc
    41761 tagattatga tgcatctcag taggataaaa gaaaatgagc agaaaaacca acaaaccagc
    41821 gatcaagacc ggtccgaaga tcatccataa gcgtttaagc attttgtagc tccacaatac
    41881 cagctatgat tttattagct gtattccagt cgtcacgacc aaactctgtt acagggacac
    41941 gaatgtcaaa acggttctca atctccacaa tcaactcaac cgttcccata ctatccaaga
    42001 cacctgcatc aaaaagatct tcatccatca tgtcagaaac atcttccata aacaactcat
    42061 caataatttc aataacttct gatttgatat ccatatttta tttcctttta ttttttaaac
    42121 catagattat tcaagaatcc agaaaagatt aagaatgaca acatgacaac atggaaagtg
    42181 ataaccatgc caagcaactg aatccagcga ttctcaggta gggcagcctt ccctgctttt
    42241 ttccgttcct tattgagcgt ttttttcttg cgaacccagg catcattgat gaccaagcct
    42301 agtccatgaa agagtccata ggcgatatag taccaggtca caccatgcca aaatcccata
    42361 atcagcatat ttacaatgta ggccatgctt gaggttacat tacgattttt aaagactttc
    42421 tttctggtta acaccatcac cattcgcata aagacaaagt cacggaacca gaaggacaga
    42481 ctcatatgcc agcgattcca aaactccttt aaatcccttg ataaaaaggg cttgttaaag
    42541 ttgatagggc tacggattcc catcaagttt gagatggcca aagcaaacat agaataacct
    42601 gcaaagtcaa agaagagctc cagaccaaaa gtatacataa ctgccaaggc atagagatta
    42661 aagaagccac ctgactgcaa ggctaaattc ttcagaggag gtagtaaggt ctctcctaaa
    42721 acatgagcta ggataaactt atacaaaaag ccccgcatga tatagcggac agattcatcc
    42781 agcatatcca tcaactcatc tcgctcagga atggcctgat aattttcatt aaatcgctta
    42841 aaacgatcga ttggaccact cgagaaagtt ggcatgaaga gaaggaaacg gaggaattcc
    42901 cagagggtaa aatccttaat cactccatct ctcagctcga tgataatccc aaccgaacga
    42961 aatgtcaggt aagaaattcc caagaaccca agcaaagact gcgttccatt gatagctggt
    43021 tgcaccttga caaagataat cggaagtagg gacagaaaac taactaagta gaagacccac
    43081 ttgccatcct tgctttttcg ataatgcttg tagaaaagca ggagcaatat ttcccagcaa
    43141 aggtaaatac ccaaggcagc tagttgattg gtctttccac ccaccaacat ggtgacaata
    43201 aagaagagac ttaccaacac ttcataccag gcaaagcgtt tcttgaaaaa gagacctata
    43261 aagatgggca aggttgcagc aatcacataa acaaaatact gaggattgcc atatggctct
    43321 aaatgaggaa gctgttgaaa aaactccatc atctcttatt cacctcgtta atcaatcctt
    43381 tgatgtcaat ctttccattt ggagttagtg gcaaactgtc tcggtaaagg aatttagatg
    43441 gcatcatgta ggacatcatg atgtctgtca ggtcttcctt gatggccttg gtaatatcga
    43501 tatctcgctc aaactgctca cgaacaccgt cttttaagat gacataagcc aatagatttt
    43561 gtaccttgtg gtccttgtta tagcgcggta ctgcgacagc agattcgata aagcgagact
    43621 tgttgaggtt ttgagagaca tcttctaact caatgcggta accgttaaac ttaatctgga
    43681 agtccatgcg tccgccgtag agaagcaagc cctcatctgt catggttccc acatcgcctg
    43741 tgtgataggc tggcagacct tcaaactcaa agaaggcttc tgctgttttt tcaggattgt
    43801 tcatataacc ttttgaaaca gctggcccag aaacaatgat ttctccctgt tcgccatttg
    43861 gcagtttatt tccttcctcg tcaatgataa aggttggaga atcagccttg gtatagccga
    43921 ttggtaggcg tttgagagtc gctaacatct cgtctgtaac agcaactgct gacagagcta
    43981 ctgtcgcttc tgttgggccg taagcattga tgatacgggc atttgggaaa cgctcgcgca
    44041 gtttttgagc tgttttgacc gtcaattctt caccatcaaa gtagaaatgc gtgattccag
    44101 gcattttctc actgttgaag tattcagaca acatggccat atctgcaaag gatggtgttg
    44161 atgtccagat agcgattggc aatgaaaaga tagccgcaaa gagttgctta aagtcctgag
    44221 tgatgactga aggaagagtg aaaagcgtac caccaagtgc caaggtcggt gcccaataca
    44281 tgacagacaa gtcaaaagaa taaggtggct gtgccagcat ttgcggacga ctcggtgtcg
    44341 caaattcctt atccgtaatc atccagtttg taaagctgag gagattatca tgtgaaatct
    44401 gcactccctt aggcttacca gtcgtaccag aagtaaagat aatgtagtaa ttatcatctc
    44461 ccttgactgg atgcgtgatt tcatagttgt tcccttgggc aaaggcttct tgaacctgag
    44521 ctagatttat cattggtgta gaaacctgct ccaagggaaa ggctgaaatg gcaataatca
    44581 agcttggctc tgctacttct aaaatagctg aaactcgctc caaggccgaa tggctatcaa
    44641 ttggaatgta ggcatgacct gacttagtca gcgctacaaa ggttgccaac atttcatatt
    44701 cttggccacc aaaaacaacc acaggagact tctcaggcaa gcctagttgg tcaatgactg
    44761 cagctaaact atccgaatca gcctttaaat cgccataagt gtgttcctgc cccaaaacat
    44821 tatagacagg atagctaggc tgtgtctgag caaaatgctc aatggtttca atcatatctg
    44881 ctattggttt atttgacaca atagggattc tccttcaagt taaaattcat tatagataaa
    44941 gcttccttga ccctgaccaa gatagctaaa gaagtaaagc agccctagaa agataagaaa
    45001 atacaaggct gtccgaccaa gaaagaggta caattctttt ctctgtttca tcaagaaaaa
    45061 ccattcattt ctgtaatttt tcgctaaaat aagagtgatt cttactagct tatttttcta
    45121 ccattgtacc actttatata gtatcttttc aattgtttac cgtatgtttc caatagattt
    45181 cagcttattt taaggattat gcggtttttc tatatctatt tcaaaagaaa aaagcctgag
    45241 attttcatct caagctctag caataatagt tattttctaa actaaaaaag tgagaataca
    45301 agcacggcca aggctgctcc gataacaggg cctacaacag gaatccaagc gtaagaccag
    45361 tctccgtctc ccttgtttgg aattggcaag atgctgtgca tgatacgagg tccaaggtca
    45421 cgagctgggt tcaaggcata acctgttgtc ccacctagtg atagaccgat accgacaatc
    45481 aaagttccca ctgcaaaggt tccgatacct gcctgaaagt cgtaaagacc caaagcaaag
    45541 attgtcaaca ccaaaacaaa agttccaagg atttcgctaa tcaagtttga tacagtatcc
    45601 ttgatggctg gtccagtact gaaggttgcc aggatattgc ctgcattttc ttctgcctca
    45661 tagtgaggtt tgaattgcaa ccaaaccaaa atctgaccca gcatggcccc tgcgaactgg
    45721 gctaagatat aaggcaaaac ggaagcccaa ggcaaaccac cttttaaggc cacaccgatg
    45781 gtcacagctg ggtttaaata agctggactg agcttgccag atacaaagac tgcaaccgca
    45841 actgcaatcc cccaacccat agtaatcaca atccaacctg agctattgct cttggtttta
    45901 ggaagaacca cacctgcaac aacaccattt cctagaagaa tcaggattaa agtccctaga
    45961 aattctccaa ataattcatt catcatcttt ctgtctccat taaaaagaag ggacgggcga
    46021 caaggaatgc tgccctccac ctcttttatt ttttcttaat tttttaattc tgctaaatcg
    46081 ttgttagcga gagctgcttc gacatcagca cggtaagttg ctttttcttc ttctgtccag
    46141 tcatagaatc gtcccatttc atccaaaatt ggctcaacga tactatccaa gctatcacgc
    46201 ataaagagca tgtgattggt acgacgaaga aggaagtcaa ctgggctaag agtcaactca
    46261 ttgcgcattg catagtgaag ggacaaggtg tctgccaagc taagacctgg cgcttgttcc
    46321 aagctgtgag caagtgcaaa gaccttcggt gcatttgaac cgtaaagatt tgctaggtaa
    46381 tgagcttcct tgctatccaa accacgtgaa actccaagtt gcgcaaaggc ttcgatttct
    46441 gaatccacat ttgctgggtt caattctcca cctgaaacag ggtaagtttt agaattgatc
    46501 aatttaaagc tacggtcaaa ttctgctttg aggatgtcaa ccacgcgctc catagctcct
    46561 tcagccatct tacggtagtc tgtgatttta ccaccagcaa gagtcaagag accattgtca
    46621 tcacggtcca agctagaccc acgagaaact gcagatggat ccaaatgttt ctcagatgtg
    46681 ctactttcaa gcttgctgac agcagactca acatcttcac gtgttttttc tttggagaga
    46741 taagattcaa cagtcgcaat caagttgtca aagctttcat cactgatggt accgttattt
    46801 ccaccattat agtcagaggc actgttccct gcaatcaatg gacgaagacc tgcccagctg
    46861 ctttcgatat catcaatggt gatgttggat tctgggaagc ggttgttgac aatgccaagt
    46921 agataatcta catcttcttg agttactttt ggatgctcca aatcacctgt gtagtctgta
    46981 tcagttgtac caaagtaagt cttgttttca cgtgggagaa caaagaccat acgaccgtca
    47041 cccaaacctg tgtcgaagta aactggctgt gaaaccttga ttttacttga atccactacc
    47101 aagtgaactc ccttagttgg gcgcatttgt gagaattgcg ttcccttatt agacaaatta
    47161 cgtactttat cactccaagg acctgttgta ttaataacca gacgggcctt gatttcaaat
    47221 acttggtctg tcaagagatc acgagctaca acacctgtaa tcttgccact ttcgtcaaag
    47281 aggaagcctt ctgccttcac gtggttggca atgagggcac cgtcttggtt ggcacgtttg
    47341 atgttttcaa tcacgagacg cgcatcgttg ttacggaagt caagatacac tccacctcct
    47401 accaagcctt ccttcttcaa gtttggctgg cgttccaaga cttctttctt gctcaaaacc
    47461 ttgttcgcag ttggtgtgtt gctcacacct gctaaaaggt cgtacaagtc catggctact
    47521 ttaagacgga agaggctaaa ggttgctcca tcttcatcgt aaactggtaa gagcattgga
    47581 tctggttttg gaatgtgtgg agcgatttgt tgaaccactg cacgttcaga aaccgtatct
    47641 gagaccactt ctacgtcgaa ttgtttgagg tagcgaagac ctccgtgaac caattttgtt
    47701 gaacgactag atgttccttc tgcaaagtct tgcatttcaa tcaaaccagt ctcaagaccg
    47761 ctagctgccg cctgcaaggc tacaccagct cctgtgattc ctccaccgat aatcaagagg
    47821 tccagggtgc gttcctgcat ttttttaatt gacaattcac gtgttttctt tgaaaattcc
    47881 atatttacac actttctaaa taaatcgctt tattctgcca gtattagtcg tctacttccg
    47941 caaagacttg agttgctttc acagccttct tccagccctt gtagagttgt tccttgcgag
    48001 attcattcat agatggctca aagagttctc ctgtctcgtt caagagtttc aactcgtcca
    48061 agtctttcca gtaccctact gataaacctg ctaggaaggc cgctcctaga gctgttgttt
    48121 ccaagttttt agcacgtgca atatcaatgc ctaaaatatc cgcctggaac tgcatgagga
    48181 agttgttcat ggctgcacca ccatccacct tcaatacttg aatggcagtc tgagtatcca
    48241 cttgcatggt gtcgatgatg tcacgcactt gataagcaat agattgcaaa gtcgccttga
    48301 taaagtcttc tttgcttgtt ccacgagtca aaccaaagac ggaaccacga gcattttggt
    48361 tccagtatgg agcgcctaga cctgtaaagg ctggaacgac ataaacttca tcgttgttgt
    48421 gagaatcacg agcgtatttt tcagattctg gtgaattttc aaccatgcga agaccgtcac
    48481 gaagccactg aatagcactt cctgcgatga agatagaacc ttccaaggca taataaacct
    48541 taccgttgat tccgtaacca atggttgtca agaggttgtt ttcagacaac tgcatctctt
    48601 ccccagtatt catgatgatg aaagagcctg ttccataagt attcttaacc atacctggct
    48661 caaaagccaa ctgtccaaag agggctgctt gttggtcccc agccatacct gagattggca
    48721 cctctccacc gtagaaatgg aatggagctg tcttgccgta gatttcggag ttagaacgaa
    48781 cttctggaag tatagccttc ggaatgttaa ggatttccaa aatctcatca tcccatttga
    48841 gttctttaat gttataaagc atggtacgag ctgcatttga gtagtcagtc acgtgagccg
    48901 caccgtcagt caatttccaa accaaccaag tatcgatagt accaaagagc aattcccctt
    48961 tttctgctcg ctcttgagcg ccttctacat gatccaaaat ccaacgaacc ttggtagcag
    49021 agaagtaagc atcaataatc aaaccagtct tttcatggaa tttttccaca taaccttggc
    49081 tttttagttg ctcagccaaa ggtgctgtct ggcgtgactg ccaaacgata gcattgtaga
    49141 taggaagtcc tgttttctta tcccagacaa ccgttgtttc acgttggttg gtaatcccga
    49201 ttgcctcgat ttgatttggc ttgacgccac tttcgatgaa agcacccgca ataactgact
    49261 gaacagagtt ccaaatttca ttggcattgt gctcaaccca acctgcctga gggaaaatct
    49321 gggtaaactc tttttgactc gagctaacct tttccccttt tttgttgaaa atgatggcac
    49381 gagaacttgt agttccctgg tcaatggcca tgatgtattt ttcttgtgac atgtactgtc
    49441 ctcctgataa agatcttgag gtgtttcctc tttacactta ctagtataca aaataaagcg
    49501 ctttcttgtt tatcaacttt ttttaatttt taaaaaaatg tgaggagatt gtgtgaattt
    49561 cacaaaaaag acctggatta accaagcctt ttaagtgaat aataactgac gaatccctgc
    49621 caaatcttcc atatccaagt cattttttaa ataatagact ggggtctgtt ccttcttatg
    49681 aatcgggtta ttggtaacca gcaaatcata atgccgacta gggtcataag cttcaatggt
    49741 aataaaacga ttgtattcca aataccgttt caaaatggct gccatccttg aaaagacaag
    49801 aaaaccagat gtcaaatcca gaccaatccg catatgctgg ccaccgtttt cagccatata
    49861 ttcgattaac tggagccatt cccagagaat cttcttatct aaatctgtcc cctgttgaaa
    49921 agcaggtaga gcatgaaaaa tctcctctgc tgtctcttta aaatcatgtt ccatcagtaa
    49981 atatggatga cgattctcta actggtactt gtagcgatcc tgtaaaatat agcccttata
    50041 gagatagact tgagcacaaa gctgactgag ttcataggtg acatggtcct ctgtataatc
    50101 ccccaatagt tcctccttct tcatttcttg aatcaattgc gtcagtaaat ctgccaactg
    50161 ccctccaaaa ccaagaatat attccatagt atgaagagga agaatgcgat gagataggag
    50221 aaaagagaag aatatcatca tctcaccatc ctcaactcct agtggaatat gttgcccagc
    50281 aaaaaaggac ggaacctttc tcagcaaacg aagatagaag atattgtcaa aataccctcg
    50341 cattttctct tctatgactt gaaactgaca agcattgacc cgaagacgtt gttgactgat
    50401 gtgagcccag agaaccaagt ccaatttctg ccccacagac aaacttgcac cgcagatttc
    50461 ctctaaattg gcaatctcct gttttctctc tggtttctgc atgtgacctt cccattcctg
    50521 actcgaccag acctttcgga aaagacagaa atagaaatag cgaatctgat gctctggacc
    50581 tcgccaacgt ccattttgga tggataaatc aaattctgac aaaatctgat ttaaaccagc
    50641 caagtgacga ccaagcgtag cctcgctaat caccaattct tgagccagct gatgggctaa
    50701 aaactgttgg tggtagagaa gataaaccaa aatctggtat ttaacagcac tctccaaaaa
    50761 caagctccga atatctctcc ccttggtagc tgcaccgata gacagacgca gattttcatc
    50821 ttctgagtga atagccagct ctaagccact atccaaagcc ttgtcattga gcagggtgac
    50881 atatttggtt agggttgctt ttgaaaatcc tgtttcttcc attacagcct tgacggtcgt
    50941 ctgagactct tgtaatagaa aggaaaggat tgaaaattga ccacactcgg ctttctccat
    51001 caaatctcct aaatacattt gttacccctt tcattttcta ccttaagcat agcataaatc
    51061 ttacaaatgc taaaataatc tgtttctctt tttattttca tgctgatttc ctggtccatt
    51121 atcctgaaaa tcagtaaaca cacggctccc cctttgggca tttttatgct aaaatagtag
    51181 ctatggataa aattattaaa actatatcag aaagcggagc ctttcgtgct tttgtccttg
    51241 atagcactga aaccgtccgc actgctcaag aaaaacatca aacccaagct agctcaactg
    51301 tagcgcttgg tcgaactctt atcgccagcc agattctcgc agccaatgaa aaaggaaata
    51361 ccaaacttac agttaaggtg ttgggatcta gctctctagg tgctattatc accgtcgctg
    51421 ataccaaggg gaacgtcaaa ggctacgttc aaaatcctgg tgttgacatc aaaaagactg
    51481 cgactggtga agtcctagtc ggaccttttg ttggaaatgg tcaattcctc gttatcacag
    51541 actacggtac tggaaatcct tacaactcta taactcccct catctctgga gaaatcggtg
    51601 aagaccttgc cttttacctt actgaaagcc aacaaacgcc ttcagcggtc ggcctcaatg
    51661 tccttttgga cgaggaagac aaggtcaaga ttgcaggtgg tttcctagtt caagtcttgc
    51721 caggagccaa gaaagaagag attgctcgct ttgaaaaacg catccaagaa atgccagcta
    51781 tctctactct tctcgaaagc gacgaccata tcgaagccct cctcaaggct atctacgggg
    51841 acgaagccta caagcgtctt tctgaagaag aaatccgttt ccaatgtgac tgtagccatg
    51901 aacgctttat gaacgctctt gccagccttc caagctcaga cttacaggaa atgaaagagg
    51961 aagaccacgg ggtagaaatc acttgtcaat tctgccaaac tacttacaac tttgatgaaa
    52021 aggacctgga ggaactcatt cgtgacaaat cttaatacac cttttatgat tggcaatgtt
    52081 gagattccca atcgtaccgt tttagcgcct atggctggcg tgaccaactc agcctttcgt
    52141 accatcgcaa aagagctcgg agctggactc gttgtaatgg aaatggtctc tgacaaggga
    52201 atccaataca acaacgaaaa aaccctgcac atgcttcata tcgatgaggg cgaaaaccct
    52261 gtctctatcc aactttttgg tagcgatgaa gacagcctag cacgcgcagc agaattcatc
    52321 caagaaaaca ccaagaccga tatcgtcgat atcaacatgg gctgccctgt caacaaaatc
    52381 gtgaagaacg aagctggtgc tatgtggctc aaggatcctg acaagatcta ctctatcatc
    52441 aacaaggtcc agtctgtcct tgatatccca cttactgtca aaatgcgtac cggctgggcg
    52501 gacccatctc ttgcagtaga aaatgctctc gctgctgaag ctgcaggtgt ttctgccctc
    52561 gccatgcatg gccgtacccg tgaacaaatg tatactggcc acgcagacct tgagaccctt
    52621 tacaaggttg cccaagctct aaccaagatt ccattcatcg ccaacggtga tatccgtact
    52681 gtccaagaag ccaagcaacg catcgaagaa gttggtgctg acgcagtcat gattggccga
    52741 gctgccatgg gaaatcctta cctcttcaac caaatcaacc attactttga aacaggagaa
    52801 atcctacctg atttgacctt tgaagacaag atgaagatcg cctacgaaca cttgaaacga
    52861 ttgattgacc tcaaaggaga aaacgtcgca gttcgtgaat tccgcggcct cgctcctcac
    52921 tatctccgtg gaacatctgg cgctgccaaa ctccgtggag ccatttcgca agctagcacc
    52981 ctggcagaga ttgaagccct cttgcaattg gagaaggctt aatagtttaa aacccgtaac
    53041 tctcttaaag agcctcttga atgccgccat tctttcctca tcaaaaaaac tccgtagtct
    53101 ctagcgctat aaatccagct agagattaca gagttatttt ttaatctaaa cttcctacaa
    53161 gggtatatta tctactgaaa ggatatggta tttgtaggga atactttaaa gagttcttac
    53221 aggaagtcag tattaactag ttatattagg tttagtttac ccattcacca ttggcattga
    53281 ctctatagct atctacagtt gtgttgactg caagggcacc tgagccattg acatagtacc
    53341 atttatctga tactttgaac cattggcttg ctttcatagc acctgatgct tcaagatagt
    53401 accaggtatc tccatctttc acccaatctg ttgccattga accgttagcg tttaggtagt
    53461 accatgaacc attgttttgg agccatcctg tcaccattga accattagcg tttaggtagt
    53521 accatgagcc attgttttgg agccatcctg tcgccatatc accattagcg tttagatagt
    53581 accatgaacc attgttttgg agccatcctg tcgccatagc gccattagcg ttgaggtagt
    53641 accatgaacc attgttttgg agccatcctg tcgccattga accattagcg tttaggtagt
    53701 accatgagcc attgttttgg agccatcctg tcgccattga accattagcg tttagatagt
    53761 accatgaacc attgttttgg agccatcctg tcgccatagc gccattgctg ttgaggtagt
    53821 accatgagcc attgttttgg agccatcctg tcgccattga accatcagta ttgtagaagt
    53881 accacatacc gttttcttgt ttccagcctg tttttggagt agatggttgt gctggttttt
    53941 cagtttttgg cggttgctgt tgagtcaagc gattatattc ttcttctgat ctacgagcat
    54001 agtcttcttc agcttgttga tcagctggtt tttctgcttt tggttgttca gctggattct
    54061 ctggttttgg agctggagct ggtttttctg gttgaggagc cggcgctggt tgtggttgtt
    54121 cagctggttt ttctttaact ttatcttctt ctgctgcttt tcgtttagct tcttctgctt
    54181 ttttacgatc tgtcttgatt ttttctaacc ttgtagcctc agctttttta ctctcaactt
    54241 ccgcttttgc ttgcttaact ttttcctcgt ttcgagatcc cttagcttcc tcttttacta
    54301 gttcaagctc cgctttttta acttccacat cggactcagc aatttcaagt tcaagcgttt
    54361 tgtaagtaat ggttgggtag ttacggtgat cttcttcttt ttgatccttg gcttttttct
    54421 tagcttcttc aaccttcttc tgagcttctg ctaccttttt ttctggtttc agggatgggt
    54481 ttggaagagt ttcttcacct acgctagaat ctgaagactt cgcatcattt tcttttttat
    54541 caggtgttgc ttgctctcca ggaactcctc gttttgcccg cccctttggt ttaccttgct
    54601 ctttagcatc tgctcttcgt ttagcttctt cttctgcttt tttacgttct gtcttgattt
    54661 cttctaacct tgtagcctca gctttttcac tcttaacttt ctcttctact tgcttaattg
    54721 tgccctcgtc tcgatgttcc ttagcttcct ctttcaatag ttcaagctcc gcttctttaa
    54781 ctttcacatc ggactcagca atttcaagtt cgattgtttt gtaagtattg gttgggtagt
    54841 tacggaaatc ttcttctttt tgatcctcgg cttttttctt agcttcttca accttcttct
    54901 gagcttctgc tactttttta gtaagttctg gttctttttt aaactgctca aaagctgcgt
    54961 ctaactctgc tttagctttt gacggcaact cagctttcga cttctcttct aataaaacat
    55021 taacttctaa ttcatacaaa tacttctttt taatttcgct caactttgtg attaagccga
    55081 cattttgggt atgtcgatct ttttccaaac tttttctgac cttctccaat atactttgat
    55141 aatgcgactt gacttcatca gcatacttct tcgatgtatc ttgcccacta gatgtaaccg
    55201 tggaggtatt cctaccacca accccttctg catggactac tcctcctaag aacaagctgg
    55261 caactgctac actagctact ccaatactaa atttacgaat tgaataatgt acttttcttt
    55321 cgctttttga tgcaaacatg tttatttcct tctatatttt ttctttaacc ttactatatc
    55381 acttcaatat gaactgtata taaatcgaat tttgtattta tctctttatg cttccatttg
    55441 ggattataac ttcatgtaat agcttttcct cttcagctat tcgtcgatac aaaataactg
    55501 cataaactgg aaaaactaaa acaaaagtca tataggcatg actcaacaag gtcaagccaa
    55561 tcaactcagg taaaatattt aaaaagtaat tagggtgttt tactgtccta aacaagatat
    55621 gatctacata tttgtgatta ttgacaagca taagcttcac tgtccaaata tctcccaaca
    55681 agtgaatcac caacatcaac atcagcatag aaaaaataag caagactaaa ccaaccatgc
    55741 ccatgccatc aaaaattgtc ttgtgcacca ttgcctcaac caagcaagag agataaaaaa
    55801 caatatgagc catagttaat cgttttgtat tctcaactcc aaattctttc ccgccattgc
    55861 taaggattcg tttctcattc tctatcgaac gctttaaaaa aatcaatcga ataaggaatg
    55921 ttactaaaat aatcgctaat accatattag tatcctttct tttatctaca caaagaataa
    55981 cacacttatg ttaaccctat atgaacttta ataaaaaact aatctgtcta caagctaatc
    56041 ttaaattcca taccgtgttc ataagggaga aaactataat ccatttgata gctttctaaa
    56101 atattattca caatgtaaag acccaaaccg gaactttcat ccttatctgt cacgatttga
    56161 gaatgataga atatatcaaa taaatgttct agttcttggt cacttagagg cgcacatgta
    56221 tttttgatag agagatagcc atcttgctcg gatatgatta cgcgcccatt tttatctgaa
    56281 tatttaattg cattactaat caggtttgtc aaaaccttat ccaatgccct aagactcatg
    56341 acgaccctgg tagcatctgt caattgattt tcaattgtaa cacctattga atgagctaat
    56401 tcttgataac gtgataaaat atctactaaa actggcttaa cagtcaaggt ctcacgacac
    56461 tctgtccact cttggaattt agaagactcc agtacttctt ccaataagtg gctcatctgg
    56521 tcaatcttat ttatactctt tgcaatatat tttggatgat ctttgtaatc tccaatatta
    56581 tgctgcatat tctctaggat aattctaaga ctggctaaag gggttttcaa ctcatgtgat
    56641 gctccgcgga caaaggaaac cttttgattt tgcaatttta caatttgctc attacgactt
    56701 tccaactcat gaataacctt caacaagtgc tcatacatac cattaatctg ttttccaact
    56761 tcaccaactt caccaacttc atctttccta ctttcatcaa aacgaatatt gtcatccaaa
    56821 tcttgcattt tactagtcac ttctgaaatg taaaaaagag gattgagcaa gcgtttagta
    56881 taaaaataag aaaaaacaaa ggaaaaagca attgtaacca aaaatgtata tgggagatac
    56941 aaaagcaaaa tattctttgc ttctttgtag acatccaccc cgtgaacaaa ttgcactgtt
    57001 acctgtttac catctgctgt actaacagac atatctaaca tcacgatata atttgatagc
    57061 tttccatctt taatatccaa gtcatgcaca agagggagtc gcttatctac aatatctctt
    57121 ttaaggtgag cagatatggt caaggacttt gaataagact ggagtaagct tggaatttca
    57181 tcagatgtct tagtctttaa atactccgta aacactcttg cgctctcatt aaacttttcc
    57241 ccctccagtt gaatataata aaaaggaaag gtcaaataaa tagctatatg aatgactaga
    57301 ccaacaccac ctagaattgc aaaacttctt aaaaaagact tggttaataa tttaggattt
    57361 tttatcataa gctaatctta tacccaacat ttttcacagt cacgatacaa tctaaagcta
    57421 attttttgcg aagagtacga atatagacat caacgaccct atcacaaggt aaatcagcta
    57481 catcttttga aatttcttcc aatatctgct ctctacttaa aacttgattt ttatgctgaa
    57541 tcaaacactt tagtaccagt aattcctttg gtttgagatc aatttcttca tttttataat
    57601 gtgctttgta agaggtaaaa tccactgtta catcctgata tcgccaaata tcctctatga
    57661 cgtagtaacg tctgataagc gccttaatac gcttgacaag cagtaccaaa gaaaaaggtt
    57721 ttgtcacatg atcatcagca tagagatcaa atacctgtga ctgagtagtt tcatctccca
    57781 gagcactcaa gacgatgaca ggaatatcgt gcttttgatt gatttctttt aacacttcaa
    57841 aaccactctt cctaggcatc attaaatcca gtaccatgag atggataggg agatcttgaa
    57901 atttttccaa gacctcttgt ccatccttag ccataatgac atgataaccc tcttctgtca
    57961 gaaatgctgc aattccttct ctaatcattt cctcgtcatc tgcaactaaa atgttcatct
    58021 ctctcccttt ctactaccag tctatcatct atgataatgg aatggatttc atttatccgc
    58081 tactttttgt caacaacaac gtcaatacaa gaaaatcatt catcttgcag cttatactct
    58141 tcgaaaatct cttcaaacca cgtcagctct atctacaacc tcaaagcaac ctgcggctag
    58201 ctgcctagtt tgctctttga ttttcattga gtttcactcc actgtgactt atggtcagat
    58261 gctgatactt ttattctttt atgcaatatc aaattttaac tggcctgctt tgacaccaat
    58321 cttaagtgtg ctgcctgcca ctaaatctcc cttaagaaga agttctgcca acttgtcctc
    58381 cacttctgtt tgcagggttc tgcgaagtgg gcgagctccc atctctgggt catatccttg
    58441 atttgctaac aatttcagag ctgaagcttg taatttcaag tcaatgcctt tttcagccaa
    58501 acttgccact aaaggcttga ccataatctt caccacttcc tgcatatggt cactagatag
    58561 gctatggaag accaccttct catcaatacg gttgatgaat tccggtctat aagctttttt
    58621 cagttcttca aacatgcgtt tttccatatt ttcctggtca aaacgaatat ccttagcccc
    58681 aaaaccaaca gtcttatcat cacgaagggc agtcgcacct aggttcgatg tcataatgat
    58741 aatggtattt gaaaaatcga ccttgcgtcc cttgctatct gtcaagacac cgtcatccag
    58801 aacctgcaag agaacattaa agatatctgg gtgagccttc tctacctcat caaagaggag
    58861 aacggaatag ggtttattgc gaaccttctc tgtcaactcc ccaccttctt cgtaacccac
    58921 atagcctgga ggagctccat ttagacggct ggctgcgaat ttctccatat actcactcat
    58981 atcaaagcgg ataagggctg attcgtcatc aaagagaact tctgccaaag ccttggccaa
    59041 ctcggtctta ccgacacctg tgggtcctag gaacataaag gaaccgatcg gacgcttgtg
    59101 actgcgaatt cctgactgat tacggcgaat ggcacgacta atacttgaaa cagcttgatc
    59161 ttgaccgatg acacgtttat ggagttctgc ttcaagattt aaatacttct tagcatccgt
    59221 ttgagtcagt ttttgaactg ggattcctga caagcgactc aaggtggtca aaatatcaga
    59281 ctctgtcacc aagtctttgt agacaggtac ttcctcttct tttgcgatta gctgggctgc
    59341 ctgtttccac ttgccatcca tcagggcctt gtcagctgga ctcaaatctg aatcgtctgc
    59401 ttttacatgc tttgccttat tttgcactgt tgctgctgct tcgtccaaga ggtcgatagc
    59461 agagtctggc aagtgacgac tggttaaata acgatgagcc atcttaaccg ctgtttcaac
    59521 cgcttcatct gtgatttgta cacggtgatg tttctcataa gtcgccttca aaccttgtaa
    59581 aatagtcata ctatctgcca cacttggttc ttcaatcgtc actttagcga aacgacgaga
    59641 aagagccgca tctttttcga tatgtttttg atattcttcc tgagtggtgg caccaaccgt
    59701 tctcaaagtt ccacgcgcca aggctggttt caagatattg gccgcatcca gagtcgaatc
    59761 aatcccgcta ccagaaccca tgatggtgtg gagttcatcg ataaagagga tgacttggcc
    59821 atcttcttca atatccttga tgatattatt catgcgttct tcaaagtcac cacggaagcg
    59881 tgtccctgca acgacattca tcaaatcaag ttctaacacg cgcatcttag ccatttccgc
    59941 aggcacgtca ccactagcaa tacgctgggc aagaccaagg gccagagctg ttttcccgac
    60001 accagcatcc ccaaccaaga cagggttgtt cttagtctta cggctcaaaa tttgaatcat
    60061 acgtgagatt tccttgtccc gaccgatgac tggttctaac ttgccagaac gcgcttgctc
    60121 tgtcaaatca tgcgtatagt cctcgagacc accactagga gtctgcggca tgcccatcat
    60181 attggccata gaattttgct tgtcagctac tgtacgatgg cgttggcgta aagccttgag
    60241 atcttcacga gtccagcctg cccgttcttc taaatttcga cgaagagcag caatcttgac
    60301 ctgatctttc ttgtcttcat aagaaaaacc agccctctcc aagatacgag tcgccaaggc
    60361 attgccatca tgcaaaatcg catagaggac gtgctctgtc cctagcacct tagcatggac
    60421 cactgacgct acatactctg cttcgtcaaa aagaacctgc aaacgacggg agaacggcaa
    60481 ttccgtaaag gtttcatcct ggctatagtc cgtttcagtc agttccaaag ccacctcttc
    60541 taaacggtcc atctcatacg gataatcatt taaagttgcc cctgctacac tataactgtg
    60601 attagacatg gcaatcaaca agtgccacga ctctagataa cgagctccaa aatgtccagc
    60661 aaccatgtag gcactttcga tacattcatt caatgctttt gaatagttca tcttacttcc
    60721 cttttctatc tacctcttgt atgacctgac gtagcatgtt tgctcgaaca actggagctt
    60781 cttctcctaa aacgcgatcc aaagctactg attctagcaa attcatctcc tgcttggtca
    60841 tcaattcctg ctcaaccaaa agctggagaa tatcctcata aatttcttga ctgactcgct
    60901 caccaatcga gtaaagcagc tcccggagca tttcatgatg actagaaaac tcaatccgtc
    60961 ctatacgaat gtagcctccg ccaccacgct tactttcaac caagtagcct ctactttccg
    61021 taaagcgtgt cttgatcacg tagttaatct gactaggaac aacctgaaag gtatctgcca
    61081 actgactccg ttgcaactcc acgataccag attgatctaa aatcgccttg atgtaggcct
    61141 caatatgatc cgatgtattt ttaaatctca taacaaaccc acctctctct ttaaaccttg
    61201 accttgtttg actattatac cgaaattttc tcatttttaa aagaaaaagg gcgctggtaa
    61261 aggataatct tcaccaactc cctatttttc tacttatcta agcctaattc tgccaagatt
    61321 tgacgtttgt aggcaatctt ttggacttcc ttgtcctcat cttcagacca atctagttta
    61381 atttctgaaa caatctgccc agggcgattt ttcaagatat agatgcggtc gctgagattg
    61441 agggcctcct caatactatg cgtgatgatc agggttgtta gctgcaactg cttgtgaatc
    61501 tcaagatacc aagcgtggag ttccatcttt gtcatctcat ccaaggcgct aaaggcctca
    61561 tctaagagaa agagcttgtg cccaaaaagg taggtccgga gtaaggctac acgctggcgc
    61621 atcccaccgc taagttcatg aggatacttg tctcttacag ctgtcagctg gaaggtcgca
    61681 agaattttat ccgctcggga aatagcttct gccttatcca ccttttgaat caagaggggc
    61741 agaatgatat ttccaagcac cgtcttgtgc tccaagagca gatccttttg caacatataa
    61801 ctcacgcgcc ccttgggatt ttcttcacca tcaaggacaa ttctccctga ctgaacttct
    61861 aaaatcccag cgattagatt aaagagggtg gtctttccaa caccacttgg gcctaggatg
    61921 gaaaccactt cgcctgaagt cacctgtagg ttgatatcct ctaaaatcct ctcctgacca
    61981 taggcataac tgacgtgctc tagtctaatt tctgtcatta tttcacaaat tcgttggtga
    62041 agcctttgtc tgtcaagtct tctttaagga taccattttc tttatcccat ttgtagaaag
    62101 cattccagcg agctgcgtca aattgacccc atttttcctt gtcgcttgcg tattcttttg
    62161 acaagtattt ttgagattcg atgacaaagt cacgtttttc cttgagttca ggtgcattct
    62221 tgatgagaat atctgcagct tcttctggat gttccatggc atattggtag ccttttttga
    62281 tggcttggat gactttgcga gcttcttctt tgttatcttt cagatagtcg ttgtttgcga
    62341 tgataactgg tgaatagtag tcaaactcct tgacatagtc tttcaagtac atgaagttag
    62401 catctacacc ttgagattta gcaaggatac catcccaacc gtagtaaatc caagcagtat
    62461 caaagacccc attggcaatc ggtgtgattg agtttgagtc gttatttggt actttttcaa
    62521 ccttctcaaa gtctccacct tgagattcta ccaaggtttt caacatagca agttcagttg
    62581 ggtcattcca tgtcccatat ttcttaccaa ccaagtcttt tggactgctt acattatcag
    62641 atttacgaga gatgattcct gatgtattgt gttcaacaat agctgcaacg gcagtgattc
    62701 ctgctccttt ttccaatttc ttagccatgt agtcttggaa atacactgca aatggtgcct
    62761 ttccgttgat aaccaagtca gaagaacttt cttctggtgg caatttcaaa tcaacatcca
    62821 ctccagcttc tttgaaataa cctttttcct tggcaacata aagccctgtg tggttggtat
    62881 ttggtgtcca gtctaggata aagtcaacct tcttaagttc tgcctctttg ttgtctttag
    62941 aagcagttcc ttgaccacag gccacaagca caacagctac aagagctgtt acaagcgtta
    63001 aaaacacttt ccatgttttc ttcattttga tttcctcttt tctttttcag aaacattcta
    63061 attctacgaa cgtttccatt taataacata tttttcacta atatcgacca acttcatacc
    63121 caaaaggctg ataatcgata ccagaataat aatagcgaac atggtatcat actgaaacaa
    63181 tttcttggac tgaatcatat aaacaccaag cccctcaaag cctcccaacc actcagatac
    63241 cactgttgtg ataaaagcgt aggagacact gaccctcaga ccagcataaa agtagggcag
    63301 gctgactgga attttaaaat gccacaggat ttgccaaggc ttggcccgca tcagactaaa
    63361 caaggtcagc atatccttgt cgcaatgcct aaaaccgtcc aaaatgctga cgatgatggg
    63421 aaaggttgtc gttaagataa tcaagacaat cttgggcaaa atcccataac ctagccacaa
    63481 gaccaggata ggagctatgg caatggtcgg aatggtctga atgaccacca tcatagggta
    63541 aatcaggtca ttgagccaag tcaaactatc catgagtaca gccataagac aggcaatcaa
    63601 aactcccaaa atcagcccca gtaaagccac tctcaaggtc gcccagctat ggtgccagag
    63661 aaattctctg tcacgaacaa agggctggag aatttcaaga ggtgtcggca ggataaactt
    63721 ggggagaagt ttaagaaaac ctgctaactg ccagattgac aagactccga gaaagcccaa
    63781 tagactaatg tgtcgtctca gtatacttct caagtttctc atcaatactt aaaatctctc
    63841 ctacatttat tttgacattg gcaaagacat tgtctgcccc ctgccctgcc acttccagcg
    63901 cttcttttag aatgcgcata agctcatcaa actccccttc caagaccgtt tcaaatggtg
    63961 tcactaccat cgtcacttct tgagtttgca gataagcaat gacctgatca ataacagcta
    64021 tccgatcaat cccctgtgct aggggtaaaa cttgcaaggc aatgcttgct ttcataagaa
    64081 cctcctcttc tcgttttcct ttttaaaaaa agaaaaacct ttaccataca tggaaaaggt
    64141 gcaaaattag actaagtatc gttccctccg ctggcattac ccagatcagg tgcggtcgaa
    64201 gtttaacact tcctctcaga ctgtacacag actcccatat attatatgta tatatgatag
    64261 cgcaaaataa gaaaaatgtc aaggaaactg cttacagaaa agagcaggaa atttctccta
    64321 ctccaatttt ctatactcgt tctccatcac tgtttactct gtagccatcc accgtcgtat
    64381 taacagctaa ggcgcctgaa gagtaagaat aataccactt accagagacc tggtaccagc
    64441 ctgttttcat tgcccctgaa ctacccagat aataccacga gccattctcc tttaaccatc
    64501 ctgtctgcat ttcaccagat aatttcaaat aataccagct agaaccatct ttcagccatc
    64561 ctgttgattt ataaccattt gatttgaaat gataccaact accatttatt ttcttccaac
    64621 cgacagttga actattattg gatccatagc tagagatatt tcctgattga ttctgataat
    64681 tttgtgaaga agtcactccc tctagctgta tatagcgacg acttccgtta taagccgtat
    64741 aactcaacca cttgtagccg tctttttcaa gtatctgatc ataatgaacc ttctccccag
    64801 gataatagta atcaatcaca gttgcactaa ctaggggttc agttttgata gcagacttgg
    64861 tcttaaaata atgagttcca cctgttgaag aaagaacaga atgacctaga ggatttttat
    64921 tcacagcctc caattgaaca taacgatagc ttccattata ggcagtataa ctcaaccact
    64981 tgtagccgtc tttttcgaga atttgatcat aatgaacctt ctctccagga taatagtaat
    65041 caatcacagt tgcactaact aggggttcag ttttaatagc agacttggtc ttaaaataat
    65101 gagttccgcc tgttgaagtt gaggattgac tattcccaac actgccacca tccaaatctt
    65161 taaaatgaat aaatcctgtc atcgtgtttg cttttataat tcgtttatta taggattctg
    65221 tataaccata gttatattcc tcaatctcaa tctgatctcc cattacattt gacacccagg
    65281 caacatgacc ataagttcct gcagtagacc aagtaatgga accaatcgtc ggtgtattat
    65341 ctacacgata accttcccga cgagcacgat gtccccattc attcgcattt ccataagctg
    65401 ccggcatttc aaaaccattg acattactca aacgaaaggc tacaaaagaa gtacactgac
    65461 gagaatacat gcgccactga tcaatttcct ggctcccatt tttataataa gcaggataat
    65521 catccccacg cgcaatcgat ccatttcctc tggaataggc atagacacta tcaccagctg
    65581 ctagcatcaa tcctactact aaaaaaggaa caagcttttt aactgacatc ttcaagtaat
    65641 aacttgttcc tcttgctata aacggtaaaa ttttcattct tcctccttga aaaataatat
    65701 aaagcgatga ttgccttcac ctaaattatt cggagaaaaa agaaaaagtg agaaaatttc
    65761 tcactttagt caagataatg aatcaaattc ttttctgtaa gaatatctga gtaagtaaag
    65821 gattcaacgt aaacattaac ttgtttatct ccttccacat ccccaaactc cacaataaat
    65881 agggatggat aaacttcaat tagcttaccc aatctatttt tttggcgctt acgaccattc
    65941 tccaaagtca tttctacgac ttgtccctca tgtgccttga tttcttcttt gatttttttc
    66001 atcttggcta catctgtaaa tgcatctgac atcttatgcc tccctctttg agatacttga
    66061 aaatttattg tattcttttt ggaaaatcaa ttccactgtt ccacgagctc cactacggtt
    66121 tttctcgata ataacttcca ccttattatt tgggatacct tcctcttctt caccaccacg
    66181 ttcatagtag tcatcgcgat agagaaaagc tacgatatca gcgtcctgct caatagaccc
    66241 agattcacga atatcagaca agaccggtct cttgtcctga cgttgttcta caccacgaga
    66301 aagctgactc agagcgatta ctggaacctt caattccttg gctagtattt tcaactgacg
    66361 agaaatttca gaaacttctt gttgacgatt ttctcgacca gttcccgtga taagttgcaa
    66421 atagtctatc aaaatcaaac caagatttcc agtttcttga gccaatttac gagaacgaga
    66481 acgaatctct gtaatccgaa tacctggcgt atcatcgata tagatactgg cgttagctag
    66541 attaccctga gcaatagtat atttttgcca ctcctcatct gtcaattgcc ctgtacggat
    66601 agaatgtgac tccactaagc cttctgcagc taacatacga tctaccaagc tttccgcacc
    66661 catttcgagt gaaaaaatag caaccgtttt gtccaactta gtcccaatgt tctgagcgat
    66721 attcaaggca aatgctgtct taccaactgc tggacgagct gctaagataa tcaactcctc
    66781 ctcatgaagt cctgttgtca tatgatccaa atcacgataa cctgtcgcaa tacctgtaat
    66841 atcggtcgtt tgttgcgagc gagcttccag atttccaaag ttgagattca acacatctcg
    66901 aatgttctta aacccgcttc gatttgcatt ttcactgaca tcaatcagcc ctttttctgc
    66961 ctgagcaata atttcatcag ctggttgtga cgcttcgtaa gcttggttga cagactctgt
    67021 caacttggca attaaacgac gtagcattgc tttttctgca acaatcttag cataatactc
    67081 cgcattagca gaagttggca cagaattgac aatctcaacc aagtaagaca agccaccaat
    67141 attctgtaaa tcaccttgat tatcaaggat agtacgaacc gttgttgcat ctatggcatc
    67201 accacgatcg gataaatcga ccatggcttg gaaaatcaaa cgatgggcat acttaaaaaa
    67261 gtcccgagac tcaatgtatt ctcgcacaaa aacaagttta ctctcatcaa taaagatagc
    67321 ccctaaaacg gattgctcag ctaagatatc ttgaggttgt actcgtaact cttctacttc
    67381 tgccatcaga cttcccttcc ttttacaatc ttgtcaagaa ggtgtaaact tatccttctt
    67441 tcacacgaag attgattaca cttgtgatat cttgatagat tttcactggc acatcaatca
    67501 aaccaaccgc tcgaatcgga gcttgtactt gaatatgacg tttatcaatc ttaattccaa
    67561 attgcttttg caattcttct gcaatcttct tattggtaat agaaccaaag gtacgaccat
    67621 ctggaccaac tttttcaaca aattctacaa cagtttcttc tgcttcaagt tgtgctttaa
    67681 ttgcttttcc ttctgcaatc atctcagcgt gagctttttc ttccgatttt tgtttaccac
    67741 gaagttcacc tacagcttga gcagtcgctt ctttggctag attctttttg ataagaaagt
    67801 tttgcgcata ccctgttggt acttccttaa tttcgccttt tttacctttt cctttaacat
    67861 ctgctaaaaa gattactttc attcttcttt ctccttttcc tttatttcat ttaatacaat
    67921 ttctgtcagt ttttcacctg cttttgacaa ggttacatct ttaatttgag ctgctgccaa
    67981 attaaagtgg cctccaccgc ctaactcttc cataatccgt tgtacattca gtttactacg
    68041 acttcgagct gagatagaga taaatccttg tgtattcttc gcaagaacaa aactcgcttc
    68101 aatacctgac atggctaaca tggcatctgc tgccttacta ataacaactg tatcatagca
    68161 tttcgtgtcc ttagcctctg ctattagtac atctgaacct aatttacgcc cctgtaaaat
    68221 aagttcattg acctcacgat attcttcaaa atctgtcgca gcgatttcct ggatagcaat
    68281 actatcactt ccgcgcgttc tgagatagct agcaacatca aatgtccgac tagttactcg
    68341 cgaggtgaaa tttttagtat ccaacatcat accagccatc aaaacacttg cttgcatacg
    68401 actcaaacga tttttcttag aattctggaa ctgaatcaat tccgttacca actcactggc
    68461 actacttgca ccactttcga tataagtaat gaccgcatta tctggaaaat cctgatccct
    68521 tctatggtgg tcaataacaa tggtttgggt aaataaatca taaaattctt ttgataatgt
    68581 taaggctgtc tttgaatggt ctacaagaat caacaaagaa cgattggtca ccatccccat
    68641 tgcatcctta acagacaaca acttcgtaac tccttctttt tctatgaatg aaacagctcg
    68701 ttcaatatct ggagacattt gttcttcatc ataaagagca tagctatttt caatcacatt
    68761 gctggcgaac aactgcatac ctacagcaga gcccaaagca tccatgtcta aatttttgtg
    68821 accgactaca aaaacctgat ctacactccg aatcttatct gaaatagctg tcatcatagc
    68881 gcgcgtacga gtccgtgtac gcttgattga agcagcagac ccaccaccaa aataaactgg
    68941 atttttcgtt tcgtcgtttt ccttaacaac cacctggtcg ccaccacgta cttcagccaa
    69001 gttcaaattg agcaaagcaa ctttccctat ctcatcatga tttccatcgc cataagaaaa
    69061 tcccatactt aaggtcaagg gcaactgtct ctgtttcgac tcttctctga aagcatcaat
    69121 aacagaaaat ttatcattca tcaagccctc aagcaccgtg tagtcagtaa atagataaaa
    69181 tcgatccata cttacccgac gagaaaacat catgtatttt tctgaaaact ctgatataaa
    69241 attagctaca aaactattga tttgactaat atctgactca gaagttgcat cctccaaatc
    69301 atcataatta tccacagaga caatcccaat cactggtcga cttgttacca attcatctgt
    69361 tatggcttgt tccctggata catctacaaa atacaaaaca ccggaagaag catccatatg
    69421 aacagcataa cgcttctcac caagcttggc ataagtagac ggatttccta ctgaagcctt
    69481 aataatcgtt tgaacagctt ctaaatcaaa atcaccatct tccttggtca aaatcaattc
    69541 agcataggga ttaaaccact caacctctcc agaagataaa ttcaatttca taacacctac
    69601 aggcatctgt tccaatagag atgtcaaact ttcttccgct tggtggttta catactgtat
    69661 ctgttctaca tcactccttg tataatgcac tctcagtttc ttaaataaaa aaacatagcc
    69721 tcctacaaaa agaaacaaaa ttaaaaccgt caacagatta ttattaacaa aaataatgaa
    69781 agtggataag actccaaacg caatcaatcc tactagaata ggaaaaattg gacttacata
    69841 aaattttttc attcaaaacc tcttggcacc cattatacca taatacccct caaaaagcga
    69901 ctttttaaaa gtgtaatcag taattctatc aattataaga aaaaggtagt ttacaattca
    69961 gtaaacctac ctttacacat attgaaatta agattcttta acctctaaca aaccaatttc
    70021 gccatcctca cgacgataaa tcacattggt tgtctgatct tcaacatcca catagataaa
    70081 gaaatcatgc cccaataaat ccatttgtag aattgcttct tccaaatcca ttggttttaa
    70141 atcaatttgt tttgaacgaa caactttaga ctggacaaca tttgaatctt ccaccaaagc
    70201 atctgtaaat aattgaccag ttgctacctt atttttattt ttacgctcga tttttgtttt
    70261 atttttacga atctgacgtt caattttatc agttacaagg tcaattgaac catacatatc
    70321 ttgagataca tcttctgcgc ggagagtaat agatccaagc ggaatcgtta cttccacttt
    70381 agccgttttt tcacgataaa cttttaagtt aattcgggca tccaactctt gttctggttg
    70441 gaagtacttt tcgatctttt cgagtttaga aactacataa tcacgaattg cttctgttac
    70501 ttctaggttt tcaccacgga tactatattt aatcatatga gtaccttctt tctaaacatt
    70561 tttgttttta tgattttatt ataacgcttt cattctattt ttgcaaattt tttcctcatc
    70621 ttacaaggga aaatgttttt acatccttag caccagcttc ttccaacagt ttcttaacac
    70681 gatttatagt tgctcctgta gtatagatat catctataag taggattttt ttaggaatag
    70741 tgactccact tttaataaag aaaggaagtt ctgtccccaa gcgctctgaa cgatttttag
    70801 aagaactggc tctctcttct cttttctcta ataaatccag atactcaaaa cctgctgcct
    70861 ctaccaagcc ctcaacctga ttaaatcctc tattagcata tctatcagga cttaggggaa
    70921 ttacaacaaa ttgatactct ttgtactttt tcaactcctc acttaaaaat gaagcgaaaa
    70981 cttttcttaa caggaagtct ccatcaaact tataccgact gaaaaaatcc ttcatagctt
    71041 gattgtaagt aaaaatcgct ctatgactga ctccaactcc ttctttacac caaagttgac
    71101 aatcttgaca ctttgttgac aactctgttt tcatacaatt tggacagttc tcttccccaa
    71161 ttctttcaaa agtagaatca cagtctgaac aaagacaaga gtcatcattc ctcagaagta
    71221 agagactact aaaagttaaa acagtcttca tagtctgccc acataacaag cacttcatag
    71281 accagcctcc ttattcatca tctgaatttc cttaatcgcc ttcttgattg aagcatttaa
    71341 cccatcatgg aagaaaagca aatctcctgt cggtctatcc atgcttcgtc caactcgtcc
    71401 accaatctga atcaaactag acttggtaaa caaacgatga ttggcctcta ctacgaaaac
    71461 atccacacaa gggaaggtaa ctccacgctc caagattgtc gtactgataa gtattgtcag
    71521 ttctccatct cgaaaagctt gtacttgctc taatcgatcc tctgttacag aagatacaaa
    71581 gccaattttc tcatttggaa attgctcctg taagatttct tctaactgct cccctttctt
    71641 aatttctgaa gcaaaaatga gtaacggata agctgtcttt ctctgcttct caatatagga
    71701 ctttaacttt ggtgacaaac gattcttgtc taagtagcga ttaaaatccg ataaccaaat
    71761 tggttttgga ataatcaacg gatttccatg aaaccgtctc ggtaaattca gtctttttag
    71821 ttctcctaaa cggacctttt tatctaactc attggtcgaa gtcgctgtta aaaagattct
    71881 caatccattc tcctttacac tattcttgac agcgtggtaa agcattggat tatcaacata
    71941 aggaaaagca tctacttcat ccactatcag caaatcaaaa gcttgataaa acttcaataa
    72001 ctgatgggtt gttgcaacaa ctagtggtgt tcgaaaataa ggttccgatt ctccatgtag
    72061 caaagctatc ccgcaagaaa aatcctgttg caggcgcttg tacagctcca aacaaacatc
    72121 tatgcgagga ctagccaaac acactgcacc acccgcattg atcactttag ccactacttg
    72181 ataaatcatt tctgtctttc cagctcctgt taccgcatga actaaggttg gcttttgctt
    72241 gtctactgct tgaagcagtc cctctgacac cttctcttga aaaggagtta attggccgcg
    72301 ccatttgaga acatcttgct tcggaaaatc ctcctgcgga aaatagtata aagtttgatc
    72361 acttctgact cgcttcatca gcaagcactc tcgacaatag taagcaccga tgggcaaata
    72421 ccattcttct agaatagtac tattacaacg ttgacagaaa agtttcccct tctcctttct
    72481 cattgctgga agtttctccg ccaactgacg ttcttcttct gttaattcat tctcagtaaa
    72541 taaacgaccg agataatcta aatttacttt catacttctt tattcgtaaa aactagcact
    72601 ttagatgatt ttttagtaca attaaatcat ggaatttaga acaattaaag aggacgacca
    72661 agtccaagaa gaaatcaaaa aatctcgctt tatctgccat gccaagcgtg tttatagcga
    72721 agaagaggct cgtgacttca ttactgccat caaaaaagaa cactacaaag cgacacataa
    72781 ctgctctgcc tttattattg gagaacgtag tgaaattaaa cgtacaagtg atgatggtga
    72841 gcctagtggt actgctggtg ttcccatgct tggggtacta gaaaatcaca atctcaccaa
    72901 tgtctgtgtg gtcgtgacac gctactttgg tggtattaaa ctaggcgctg gaggactaat
    72961 tcgtgcttac gccggcagtg tcgccttagc tgtcaaagaa attggtatta ttgaaataaa
    73021 agaacaggct ggcattgcta ttcaaatgtc ttatgctcag taccaagagt acagtaactt
    73081 ccttaaagaa catgatctca tggagctgga tacaaacttt acagatcaag tcgatacgat
    73141 gatttatgtt gataaagaag aaaaagaaac tattaaagct gcacttgtgg agttttttaa
    73201 tggaaaagtc actttaactg accaaggttt acgagaggtt gaagttcctg taaacttagt
    73261 gtaaacaatg aataatacag cgtttcgttg acattctcac aactacttta gcgagcaaaa
    73321 taaaaagatg cgtaccaaaa tatactagaa aatgaagcaa ttcaaacgaa acctgatatc
    73381 gttttccttc acacctattt actagaatta gctgaacgca atcacttgaa aattaatgac
    73441 tttgatctat gatatataga aatcctatcg cttcgatagg atttctatat tttacaaatg
    73501 gtatggatag cgttatacta aagatatctt atacaaagag gtattcatat gtctatttat
    73561 aacaacatta ctgaattaat cggtcaaaca ccgattgtta aacttaacaa catcgtgcca
    73621 gaaggtgctg cagacgtcta tataaagctt gaagcattta atcctggttc atctgtaaaa
    73681 gaccgtattg cccttagcat gattgaaaaa gctgaacaag atggtattct gaaacctggt
    73741 tctactattg ttgaagcaac aagtggaaac actggtattg gactttcatg ggtaggtgct
    73801 gctaaagggt ataaagtcgt catcgttatg cctgaaacta tgagtgtaga acgacgtaaa
    73861 attatccaag cttatggtgc tgaactcgtc ctaactcctg gtagcgaggg aatgaaaggt
    73921 gctattgcta aggctcaaga aatcgctgct gaacgtgatg gtttccttcc tcttcaattt
    73981 gacaatccag ctaatccaga agtacacgaa agaacaacag gagctgagat actagctgct
    74041 ttcggtaaag atggattaga tgcctttgtt gctggagtag gtaccggtgg aacgatttct
    74101 ggtgtttctc atgcactcaa atcagaaaat tctaacattc aagtttttgc agtagaagca
    74161 gatgaatctg ctattctatc tggtgaaaaa cctggtcctc acaaaattca aggtatctca
    74221 gctggattta ttcctgatac acttgatact aaagcctatg atggtatcgt tcgtgtaaca
    74281 tcagatgacg ctcttgcact cggacgtgaa attggtggaa aagaaggctt ccttgtaggg
    74341 atttcctcag ctgcagctat ctacggagcc atcgaggttg ccaaaaaatt aggtacaggt
    74401 aaaaaagtcc ttgccctagc accagataac ggtgaacgtt atctctctac agcactttat
    74461 gaattgtaac cgtccaataa cgaagtatat tgaaaaatct ccagactaga gaactcacgg
    74521 atagttccta atctggagat ttcttatttg cacttttctt gtacaacttt agtccatggt
    74581 aaataagcct ctaaaacctc tttgtttacg agagtttcca cgtttggaag acattctaga
    74641 agataggata gatatttctc actatttata atggattgaa ataagatatg aacaaatcga
    74701 ttaggacatg atggtaaagc gtaatccctt gtttctcagc tttcccagac aaaaaagtcc
    74761 aatagtaagt cagctgacta tcactctcta gcaccctata agaagtttca tccgcatgaa
    74821 gtaaggactg cgtcaatagt ctctctcgca agaggttata aaggggctcc aaatagtatt
    74881 gactcgcctt gatatgccaa ttagcaattt ccttacgtgt gattggtaaa cccatcttag
    74941 cccaatcttc ttcttggcga taattgggta ccttcagatt aaacttctga tggatggtgt
    75001 gagcgataat agaagctgag ccaaggctat gcgccaaagg ggctttagga ataggagctt
    75061 tcacaagctt atccagatga ttatctttta ctcgttatgg acaatgctat atggcataaa
    75121 tcaagtacct taaagattcc gactaatatt ggttttacct ttattcctcc atacacacca
    75181 gagatgaacc ccattgaaca agtgtggaaa gagattcgta aacgtggatt taagaataaa
    75241 gcctttcaaa ctttggaaga tgtcatgaat caactccaag atgttataca aggactggag
    75301 aaggaggtga taaagtccat cgttaatcgg agatggacta gaatgctttt tgaaaacaga
    75361 tgagtataaa aagaaagtcc tcatttcaat agaaatcacg actttctgat ggatttatag
    75421 taaaatgaaa taagaacagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt
    75481 tttaaaagca gaggtgtact attctagttt caatctacta tatttttgga gtgatagaaa
    75541 agcccttcat aagctagtct acttgttcag gtgcgagagc tttgacatcc ttttctgtac
    75601 ttagccaagt cagttttccg ttctcaaagc gtttatatag tagccaaaat ccttgaccat
    75661 cccagtaaag ggctttaaag cggtctttac gtccaccaca aaagagaaag acttgaccgg
    75721 agaaagaatc caattcaaag tgggttttaa ctacataggc taatgagtct attccctgcc
    75781 tcatatctgt cttgccacaa acaaggtgaa cttgacctaa atcacttagt tgaattatca
    75841 tagtacaata cctttcctcc gataattatt ttttatctag tatactggaa gttggggaat
    75901 taggatagat accttgttat gacgcgctta ctatgaattt taagtatagt ctcctaaatg
    75961 cacttaaccc ttattatagg gctttttgtt ttaattattc taatcgagtg agactgggga
    76021 aaaaacaatt tcaggaaaaa tctaagccct atacaaaaaa ggaagcaatt tgcttccttt
    76081 ctattattag ttattcaagg ctgctgccat tgtagctgca acttcagctt cgaagtcgtt
    76141 tgcagctttc tcgatacctt caccaacttc aaagcgagca aactcaacta ccgaagcgtt
    76201 aactgattca aggtatgctt caactgtctt gctgtcatcc atgatgtaaa cttgtgcaag
    76261 aagtgtgtaa gcttggtcaa ctttagtgtt atcaagcatg aagcgatcca ttttacctgg
    76321 aataattttg tcccagattt tttctggttt gccttctgca gccaattcag ctttgatgtc
    76381 agcttcagct tgagcaataa catcatcagt taattgagct tttgatccat acttcaagtg
    76441 tggaagagct ggtttattaa ccattgcacg gctttcgttg tcttggtcga taacgtgatt
    76501 caattgtgcc aactcatctt taacgaattg ctcatccaat tctttgtaag aaagaactgt
    76561 tggtttcatc gctgcgatgt gcattgacaa ttgtttagca agtgcttcgt ctccaccttc
    76621 aacaactgaa ataacaccga tacgtccacc gttatgttgg tatgctccaa agtgttgtgc
    76681 gtctgttttt tcaatcaatg caaagcgacg gaatgagatt ttctctccga tagttgctgt
    76741 tgcagatacg tatgcagctt caagagtttc acctgaaggc attatcaaag caagagcttc
    76801 ttcattgtta gcaggttttc cttcagcaat gactttagct gtagtattta ccaattcaac
    76861 gaattgagcg ttttttgcaa cgaagtcagt ttcagcgttt acttcaataa ctgctgcaac
    76921 attaccgtta acataaacac cagtcaaacc ttctgcagca acacggtcag ctttcttagc
    76981 tgccttagcc ataccttttt cacgaagcaa ttcaatcgct ttttcgatgt caccgtctgt
    77041 ttctacaagc gcttttttag cgtccataac accggcacca gatttttcac gcaactcttt
    77101 tacaagttta gctgtaattt ctgccatttt aattctccta tattttttga aaataggaga
    77161 gccgggctaa gccccgccct cctaggtaat tactatttgt ataaattaag cgttgtcacc
    77221 ttctacaact tcaacgattt cttcaattga atctgcttga gtttctgaag ctgcaaattc
    77281 tgcttcaact gctactgcat cctcaccttg acgtccttcg ataatagcgt cagccaattt
    77341 agctgtgatc aatttaacag cacggatagc gtcatcgtta gctgggatga ttacatcgat
    77401 atcatctgga tcagtattgg tgtcaaccat cgctacaact gggattccca attttttagc
    77461 ttctttaaca gcgatttgct ctttatgtgg gtcaactacg tacatcacat ctgggatacg
    77521 aggcatatct tcgataccac ccaagaattt ttcaagacgc gcacgttgtt tgttaagaag
    77581 tgcaacttct ttcttaggaa gaacttcgaa agttccatct tcttccatac gtttaatttc
    77641 tttcaaacga gcgatacgtt tttggattgt tccccagttt gtaagagttc cacccaacca
    77701 acggtggttg atgaagtatt gacctgaacg tactgcttct tcagcaactg catcagctgc
    77761 ttgtttctta gtaccaacga acaatacaac tgcatcgtta gctgctgcat cacgcatgaa
    77821 gtcgtatgct tggtcagcgt attttacagt ttgttgcaag tcgataacgt ggattccgtt
    77881 acgttcagta aagatgtact tagccatctt aggattccag cgacgagttt ggtgaccaaa
    77941 gtgtacacca gcctcaagaa gttgtttcat tgaaattact gccatgagta tttctccttt
    78001 ttgttttttt cctcttcttg acttcaactc gcaaaacgac ccaagggcaa ctgcttcaca
    78061 attcatcaag aatgagtatt atcgttcaca cgacaatttt cattctacca tacttttcca
    78121 atattttcaa gctattttga tataattttt aatagggatt gtcacggtaa aacctgaaaa
    78181 gagggctcta ttcgagtccc tctgtaaatt aatctgcata aatatatgta acaaaacctt
    78241 cagaagttgt tgttggattg aaccatccac ggtgatttcc aattgtacga ttacctgcat
    78301 aatttgattc tgatacttgg atacgtgttg ttgattcaac agctgtaaca accgctacgt
    78361 gaccatatcc accatcattc caacatgcaa ttgctccaac ttgaggtgtt gaacctgtac
    78421 ggaaacctgc tgctgctgca cttgtagccc actgtgctcc attaccccag tagtctccag
    78481 cccaaggtgc caatgttttt actccccatg tacattctcc aattggataa cttgaagcgt
    78541 ttgtactgta tgttggacga acttttgcac ggacaggtgc tgctgcagat tcagatactg
    78601 cttgcacttg agctgttaag ttagtgtttg ctgaagcaag tactgattgt tgttggctag
    78661 ctcgtttttc tttataagct gcttctgcta ccgcagctgc acgagcctct gcctcagctg
    78721 ctgctttttg ctctaataga cttgcttttt ccccttcagc tgtcgctttc tcagcagcaa
    78781 gacttaattc agcagctttt agttctgcct gtttcgtagt caatgcttga gcatcatcag
    78841 ccaatttttg ttgattagca attacagtat tgatagcatc attatttgct acttgttttt
    78901 cagaaatagc ttttttatct gccttttgtt gttctaacat tttgttgttt gcagatacga
    78961 tttcactcat tgcagcaaca cgtgaaatag cttctgtaat tgattttgag tttacaatgg
    79021 tattgatata gctagttacg gctccatttg tttgagcact acgagcttgt ttttccaacg
    79081 attggttacg agaaacaatg tttttagaaa gttctgtaat ctcaccctcg agtttcttag
    79141 attctgcttg taatctatca ttttcagctt gcaagttaga ctgctcagct tgaatagctg
    79201 atacttgctc ctgaatttgg tcaacttgtt tttgggcttc ttgttgttgt gctgttaagt
    79261 tactaatttt attatcttga gcagcaattt tgtcatcagt cgtttctgca tgcgcagttg
    79321 ttaaaacagc tacttgagaa accattactg tacttaataa aagtgacgct aagatttttt
    79381 tcttcatatt acgtagatac tccttctttt aaagacaata ctagtatacc aaaaaaaggc
    79441 ctaataaata ttacgccttt gttacattta tatgtcgttc ttatagataa tatttttcaa
    79501 aaataaattg aaaaacagta atccataaaa aatttaaaat catcgtcggt accaagctat
    79561 agactataaa aatcgacatg ctatctactg tcaaccctac cataaaagcc aaaagataac
    79621 tacccatttc aaacaggaat gtcagcacaa tcatagctag cattcttgtc caacgattca
    79681 acaaaataac actattcaat ttatgaagga aggctcccaa taagataaat aagagagttg
    79741 taatccctat tagatggaaa aagtaaacat cataaaccaa gcctataaca aaacaataga
    79801 ctaggtagag atactctgat acttctatcg tctcaaataa gagaaataga aaaagaaaat
    79861 gactagccaa atgtacatgg gggaaaaatg agcccagaag ctggctaata tgggcgtcaa
    79921 ttagaacaaa gaaaggaagc aataaaaata ctccaactcg cttcaactgt ctcattatga
    79981 attccccact aattctatca catctacatt atgagtatct gcactcaatt taacagttac
    80041 ttctcgtgtc aaatagtctg tactatgcgt tgtggcaacc acttcaccaa caggaatatc
    80101 agcaacgtta aagtttccta atccaccagt agtcacctta tctcccgcac taatatcgct
    80161 attactattt aattggctaa ttttaagaac gtcattttcc ttgtcatagc caataataat
    80221 tccataaatt gtagtagagc catgttgaat tttaacagaa atcttatcag cattttccgt
    80281 atttgtcaga aggttgacta tagtagagtt ctcctctact tttgaaacac tcccaatcaa
    80341 gccaccattt gcaatagcta acatgttctc agaagcacct tttgatctac ctgcatctaa
    80401 ggtcaactcc tgcttccaag ataccggaga acgcataata acatctgctg ctaaagtctt
    80461 tgtggcttgc aatttagact tcatatcaag caattggcgc agttgttcat tttctgtctt
    80521 taaactttcc acctcatttg atttaacttc taattggtaa agctgtttct tcaaactttc
    80581 attttcatta tatgttcgtg tcaaatgagc caaatctgat ttgacagaat caaaccactg
    80641 aaaaggtttt tgtacaactc tatcaaccaa tgagattcca tctcctaatt ttgtcacaat
    80701 tgtacttgaa taagttgtcg ctaagagagc tgacacaagc agaacagtga caaaaacaat
    80761 aatgacatat tttgattttt taaaacggtt catatcccta cctttatatc aaaaactgtt
    80821 acagtaactt tttatcaatt cctgaaagct actaagattt taagaaaaat aaacaacaac
    80881 caagtacgag aataacaaga atggtcagcg tatcctttag agtccatttc aattgtcggt
    80941 attgacttct gccttttcca ccctgatagc cacgcgcttc catagcgata gccaaggaat
    81001 ctgcacgttt taaacttgtc gcaaaaagag gaatcaaaat gggaatcatc gactttactt
    81061 tttgaacgat gcttccttct ccaaaatcca ctccacgagc tttctgtgca ttcataatcc
    81121 gcgtcgtatc atccatcaag gttgggacaa aacgcaaact catagacagc atcaatccaa
    81181 tttcatgaac tggaactttc acacgcttta aaggtgctaa taaagcttcg acagctgatg
    81241 ccaaacttaa aggcatggtt gttaaggtta acaaagttga aaagaaaata atcaatacaa
    81301 agcgacaaaa aataatccca gcttgttgca aagcataatc cgtgattctc acaaacgaaa
    81361 actcaaataa aacattccca ttagaaatga aaaatagttg aaaaatagtt gtgaaggcaa
    81421 tcaagaaaaa catagacttc aagccctgaa taaaaaatga aagagatact cctgacaagg
    81481 caataaatat ccctgtcgct ataaaaagaa tcagattcgt caaggggtta ttagcccaaa
    81541 acacaatcaa aatcagtagc atcatagcaa gcaatttgct acgtggatcc aatcggtgaa
    81601 caatcgaatc ccctgggata taacgcccta aaatcatact atccatttag cgactccttg
    81661 aactcctcta tcttaatcgg taatcgttta aatgacacgc ctctatcagc caatcgttta
    81721 caaaaggccg taattttagg tactcccaac tgaacttctt ccataaaaac aacgtcttga
    81781 aagacatcac ttggtttgcc cccctttact aaacgtccct tttccattac atagacttga
    81841 ttcgcatatt cagcaacatc atccatcaaa tgcgttacca agacgatggt catccctgac
    81901 tggtggagtt ttttgaacag ggtcatcaac tcctttctcc ctagaggatc tagaccagct
    81961 gttggctcat ctaagactaa tatagctggc tccatggcaa gtatgcctgc aatggcaaca
    82021 cgtctcattt gtccccctga cagctcaaac ggactacgat caaaaagtga ttcatcaatt
    82081 ccaaccagag ccagtttctc acgcgcagtc ttcacagcat cttcttcaga aactccaaaa
    82141 ttttgcggtc caaaagcaac gtccttcaaa accgtttctt caaaaatctg attttcagca
    82201 aactgaaata ccaagccaac ctgttttcta atttgacgaa tatctttatt tttagaagtc
    82261 gaggtgatta aggtatcaaa aaccctcaca ctcccttgac ttggcaccaa taaaccattt
    82321 aagagttgta aaatagttga tttaccacta cctgtgtgcc caattaaagc tgtataagag
    82381 ccatcttcaa tcgtcaaaga aacatccgac aaagctgctg aagctaaggg agtaccttct
    82441 tgatatgtaa aattcacatt ttctagagca attcccatag cttatcctct agctcacttt
    82501 ctgtcaaata attttcaggt aaattatagc cattatggct caaagatttt tttaattgat
    82561 tagcaaaagg atcgtctaat ccaatttgat ctaaatcatt tcgagagaaa agctcccttg
    82621 gactactagt tgattcaatt tccccttttt tcatgaccaa tacgcgatca ctcatggcga
    82681 cttcttccaa atcatgggta atagaaatga ccgtcatatc atagtctttt cgaattcctt
    82741 ttactgtccc aataagttct ctacgcccct caggatccaa catactcgtt gcttcatcta
    82801 agattaaaat agctggtctt aggactacaa cacctgcaat ggccacacgt tgcttttggc
    82861 cacctgatag acgcgctggc tctctctttt taaagtccaa catgccaact aaatccagag
    82921 cttcttctac tctctttttc atttcttgac gagaaagtcc ctgattttcc aaaccaaaag
    82981 caacatcatc ttcaacagtc gctccaacaa attgattgtc tggattttga aaaaccatac
    83041 cgatttgacg acgtatattc caaacatttt cctcagtcaa acgttggcca tcaattacaa
    83101 tctctccgga ttctgcttcc agtaagccat caattaatcg aaccgtcgtt gatttaccac
    83161 taccattatg ccctacaatc gaaagccatt ctccacgttt cacgtgaaac gtaatatcct
    83221 tcacatcgta gtagttctga ttttctttat agcgaaaaga aagatttttt acatcaatta
    83281 ttgatttcat ttcgaaccaa atgtcccttt aaatacatag gcactaccct tgaaatagtc
    83341 atagccagag tagatagtga aaaataaggc tacataaagt agaacttgac caagcaaagt
    83401 ccaatgtaat agcaagaaaa taatggcaaa catctgacta aaagttttaa tttttccagg
    83461 cattgctgct gctaaaattg ttccaccagt ttcaaccaat aaaagcctta aacctgtcac
    83521 agctaactca cgacagataa tcactgcaac aatccaagcc ggagccatac ctaactcaat
    83581 caacataata aaagccgaca taactagtaa cttatccgcc ataggatctg caaatttacc
    83641 aaaattactg accacattcc atttacgagc taaatatcca tctaaatagt cggtaatact
    83701 ggcaacagca aagataatag ctgcaactat atgactctct atcgaatttc ctatcgttaa
    83761 aataaagata aaaataggta taaagagaat tcgacctatt gttaagagat tgggaatttg
    83821 ttcttttttc attcgttttt ccttaatttt tagtaaaggt tacagtgatt tgtccagtct
    83881 gagctgttaa tttcgataaa tcaacagtct gattatctac tgtcaaatca acacctttta
    83941 caacacctaa cgtaattgtt acaggacttt tagttgcaac tgttgcttct gcacttttct
    84001 tctttggcga taaggttaca ccgccctcaa gttcgctttc tgaaacactg acccaacttg
    84061 taacatctga aactgccaat tgcaatttaa ctgtttcctt acttgtctta taagcgattt
    84121 ctacatgatt tccttcgcct gatacactta tagctgattc tatactagaa gaactactac
    84181 ttgaggagtg gggaacagag ctagttgaac ttgttgattg aaccacactg taattagaaa
    84241 gagaaggctc ctctggttga gtttgaatat agttccaaac ataataagtc acaaaaatta
    84301 aaatcgataa agcaaaaagg ataaaataaa ataaaggtaa aaatgatgtt tttttcttct
    84361 ttttcttact tgaacgtcta cgacctgtca actcatcttc atcaacatct acttcctcat
    84421 aagtaatcat actcccagaa tcataagcat ccaaaacaat ttggtcatct aactcaacag
    84481 cccatgcata ttttttcaag aaagaacgcg tgtaaaaagg acttggaagt tgatcgaaat
    84541 cgtctgcttc cattgcttcc aacatatcta actggatttc tgtctttttc tgcaattcat
    84601 ctaaactcaa tccctgattg attctagcta atcgtaaaac ctctccaatt gttttttttc
    84661 tcatacttgt catcccttct ttctagtgtc tattataata ggttactacg atgggaatat
    84721 tgtaaaatca actatgtcac catcatctat taaatgatgt ccagcatcaa ggacatcctc
    84781 taaagtaatt tcctgtaaaa ttttcggcaa atcaaaaatt gtctcaccat tttcaaaagc
    84841 atcatattgc gttgcaataa attcaagaga gttcatgcta ctgaaaaatt cgccaaacat
    84901 ctctcttttg ataatatcta aatgttcctc tgtaatatct aaatcctttg taaaattacg
    84961 aatagccttc ctaaattgat gagacaaagc aactggctct ttcgtatcca ttgtcaacat
    85021 gacaaaatga aagcgacttg ttacttcaac ttccagagat aaggatgcat caattttacc
    85081 tgattcataa catttttgaa aacgatccga agtccaacca aacatcattg caaacaataa
    85141 ctttaataaa atatgatgtc gatagcaatc cgcttcagaa acttctcgct tacctctaac
    85201 tccaatcgct agtttgggag aagatacttc cattctcata ctatctgttg gctttacagg
    85261 ctgtaaaaac aacttttctc ttgctacttc ctgaaaatct gaatctttca gttctttgct
    85321 ttcaaaatag tcctgtactc gctccacatc aaaattacca actaaaaaca gagacatgtt
    85381 tacaggtttg taaaactttg taaaattttc ttgcaaatta gttagattga tttgggaaat
    85441 ggactcctca cttccaacta tatcagttgc taaaggtgta ccaggataca aattcgctaa
    85501 agttgaaaag aataaacacg aatctggatc atcttggtac atttctcgtt cttgctgaat
    85561 aatatcctgc tctgtcagaa tggaagcttc agtaaagtgt gctgatgtta ccaattcatc
    85621 aagtaaatct aaattttcta aaaaataatc cgttgctgaa aaaagatagt ttgtttttgt
    85681 aaagcttgta aaggcattac tatctgcacc tagactcgta aaagccgaca tcaaatcact
    85741 agaatcttct ctctcaaata atttatgttc aagaaaatga gcaattcctc caggatattg
    85801 ttttacatct ccgtcaactt ctgtgacaaa cgtatctacc gaaccaaact gtacagtgac
    85861 actcccgtaa acctctttaa attccttttt aggcaaaaga gcaactatca atccattggc
    85921 caaacgagtt cgataaacct tttcttttac agctggatag tatttttctt caaaaacaac
    85981 ctttgtcatt ctattccttc cataaagtaa atcgtttgta gtttcacatt attagctact
    86041 ctacaaatag catctttgtc aatctgttca agctttacaa tccaactttt aaagtctgct
    86101 gaagattttc caaataaggc attttgataa gcacgttcaa tcaatgaaga ttgattatct
    86161 taagaaagta acaacgacca acgaatcatt tccttggtct gatttaactc aaactctgta
    86221 aaataacctt tttttaaatc aagcagttga ttattcatca ttttacgagc ctggttacga
    86281 ttttctcgat tgataccagc atacatcctc aagaatccac taaataaatc aagctcactt
    86341 gaaatggtat aagctaatcc agcattttca cggacatttg taaagagctt agaatgagca
    86401 aatccaccaa gtaaaccatt cattacaatc atgggtaaat gttgctcatc accatattta
    86461 gaacggtaat gataacctaa ttccaaaatg gattgtccca catttttccg aaccatacct
    86521 tcctgaagga tattagaata aggttgacaa tactgaacct tcacatctcc ttttcgacct
    86581 ttaaagccaa atgattctaa tacattttga atttcaacct cattaaaatc acctaggaaa
    86641 aagaaatcta ttcgatcatt ggctaaaaat tcttggaaac aagaataaga actttgtgga
    86701 gtttcagcta aaatacgatt tcgtaaatca ctatattcca attgaagacg ttcatcatga
    86761 aaaaacaatt tatccaattc tttatgtgca aaataaaaag aatcatccat atcagctgct
    86821 aaacttgcta gcaattgttt tttctcaatt tcaaataagg ccggatcaaa cccattatca
    86881 actactacgg gtgaaaaaag agtttctttt acaagttcca aaatctgaga ggttagcacg
    86941 tttttcctac ttaaaaactc atcacgaaca taggtaaatg tcaattctat aatgtggctt
    87001 tgccctcttc tgaaacaatt ggttgacata tctgtaccgt atagactggc caagtgtctc
    87061 ctcaaatctt gagaagtggg gtacatctga ttagcagtct ctagcatact tgcactcaac
    87121 atgtgacctg caatcgtatc aagggataat ggagcggtaa aacgcacggt aattttgttt
    87181 gttttaaact tttttgattg gataaaatgt gttgaaattc catgcactaa ctccatgatt
    87241 tacctcctta tatacagact tctattatat cacgaaaacc tgaaattttc ttattccctg
    87301 taacactttt gaaataaaaa tcgcttacat ttctctctgt ctctctcact atttttagga
    87361 aaatatggta taataccaaa gattgaggtg aattatggaa tacaaattat ttgaagaatt
    87421 tattaccctc caagcactac tcaaagaact tggaattaca catagcggag gagctattaa
    87481 atcatttctc tctgaacatt ctgtttactt taatagggaa ttagagagtc gtcgtggaaa
    87541 aaaacttcgt attggcgata aagttgacat ccctgacatg aacattgaca tcttgttgac
    87601 acaacctact tctgaagaac aagatgaata ccaagctgat aaagttgaaa aagaacggat
    87661 cgctaaactt gtcaaaaaga tgaataaggg agttaaaaaa gacaaatcga aacctgcttc
    87721 atcacctaaa agccaacaag ctccacgatt ccctggtaga taatcatgtg gctacaacat
    87781 ctatctctca agacttttcg taattacaaa gaaacgaaaa tagactttaa tcctaaattg
    87841 aatgtctttt tgggacgtaa tgcacaagga aaaacaaaca tgttagaggc tatctatttt
    87901 ttagccttaa cgcgtagtca tcgaactcga acagataaaa atctcattca ttttgatgag
    87961 gaacaacttc atctttcagg tctcgttcag aaaaaaactg gatccattcc cctagaaatc
    88021 gaactaacac aaaaaggccg tgtaacaaaa gttaatcact taaaacaggc acgcctttca
    88081 gattatgtag gacacatgaa tgttgtctta tttgctcctg aagatttaca actaattaaa
    88141 ggagcacctt cgattcgacg aaaattcatt gatatggaac ttgggcaaat taagccaatc
    88201 tacttatctg acttaaccaa ttataaccac atcctaaagc aaagaaacac ttacctaaaa
    88261 tcagatcaaa aaatagatga aacattcctt tctgtgttag atgatcagct agttgattat
    88321 ggatgtcgtg taatgaatca ccgcttagat ttcataaaaa aactagaatc atttgggcgt
    88381 aagaaacatt ttgaactctc taatcagatc gaagagttgt caatatccta tcaatcttct
    88441 gtcaatataa ctgacaaaca aaacttatcc gaatctttca aaattgcttt agaaaaaagt
    88501 aaatccagag atttatttaa aaagaatact ggtgtcggtc ctcatcgaga tgacatttct
    88561 ttttatataa atgggatgga tgctagtttc ggaagccaag gtcaacatcg tagtctcgtc
    88621 ctctcgataa aattagcaga aatcgaatta atggaaagca ttaccacaga atctccgata
    88681 ttactgcttg acgatgtgat gagtgaactt gacaacacta gacagttaaa attattagaa
    88741 acgatttctc aatcaatcca aacctttatc acaacaacaa gcttagacca tcttcaaaat
    88801 ctgccagaaa atctaagtat cttcactatt caggatggta aagctgctgt aaatggaaat
    88861 tgacaacatt ataaaagaac tcctgttttc actggagttc ttttcattgt tttttacata
    88921 gaataatttg gtgcctcatt agtaatttgc acatcatgag gatggctttc tttcaaacca
    88981 gcaccagaca tttcaataaa ttgagcatta tcgtgtagtt ctttaaggtt agctgcacca
    89041 cagtaaccca taccagagcg aataccacca atcatttgga aaacaatatc agctgccgct
    89101 cctttataag caacacgacc ttcaattcct tctggaacaa gcttgtttgc ttcattgaca
    89161 gaaccttgga aataacggtc gcttgaacct ttcttcatag cagcaattga tcccatacca
    89221 cggtaagtct tgaatttacg tccttggaag atttcagttt cgcctggagc ttcatcagtt
    89281 ccagcaaaca tagatccaag cataacagca tttccacctg cagcaagtgc ttttacaata
    89341 tctccagaat acttgatccc accgtcagca ataatcgttt taccatattc gcgcgcaaca
    89401 gctgcagcat cgtagatagc tgttacttgc ggaacaccaa caccagcaat cacacgagta
    89461 gtacagatag aacctggtcc aataccaacc ttaacaacgt ctacacccgc ttcataaagg
    89521 gcacgtgcac cttcagcagt agcaatattt ccagcaatca aagtccgatc tgggaaatga
    89581 gcacgaatct cggcaatttt acgcaagaca cctgcagaat gaccatgtgc agtatcaata
    89641 acaatcgcat ccgctcctgc ctcaaaaaga gcctctgcac gttcaaatgt atctgaagta
    89701 acacctactg cacctgcaac tagaagacga ccaaactcat ctttagccgc atttggaaac
    89761 tcaataactt tttcaatatc tttgatagtg atcaaaccag aaagactgcc ttcttcatcg
    89821 accaacggaa gtttttcaat acgatgctct tgaagaatac tctcagccgt tgcaagatcc
    89881 gtacccacag gagcagtaac aagattttca ctagtcatat ggtttgaaat tggttgatta
    89941 taatctgaaa taaaacgaag atctcggttt gtcaaaatac caaccaattt acgattttca
    90001 agtgtttcaa caactggaac accactgatg cggtaacgac ccataagctc atctgcttca
    90061 gcaattgtat gttcaggcgt caagaagaac ggatcaataa taactccatt ttcagaacgt
    90121 tttaccttac gaacctcgtc tgcttgttga gcaattgaca tgtttttatg gataactccg
    90181 agaccacctg cacgagcaat agcaatggcc atttgactct ctgtaactgt gtccatggca
    90241 gcggtaataa ttgggatatt taaagtcaaa ttatctgcca atttagttgt taaatctgca
    90301 tcgttaggca acacatgact ttcagctgga ataagcaata catcatcaaa ggtaaaacct
    90361 tttttcaaaa atttagtgtc ccaattagac attcgaagtt tcctcttttc tttctttttg
    90421 agcttgactc tttttatatt gtatctatca taccattcta tacaaatttg tcaaatgtta
    90481 caggggtaaa taaaaaacta tcttttcttc gagatagaaa tgatagtttc ttgtaaaata
    90541 aacttagtta aagtaatgaa gtcccattgc cccttttacc tcagataggg tttgacccgc
    90601 aacttcacgc gctctttcac tacctttttg aatcatatta taaacttctc ccatatcctt
    90661 agcaaattca atacggcgct cacgaatagg acccagttca cgttctaata tttcaagtag
    90721 ataacgcttg gtcttcacat caccaagacc acctcgttga taacgttctt tcatatcagc
    90781 aatttcttga gcatcttctg gacgaccaaa aacatctaga taatggaaaa ccatatttcc
    90841 ctcaatctta cctggatcct caacgcggat atgatctgga tctgtataca tactcattac
    90901 ttttttacgc aaagtatccg catcatcagc taaataaata ccattattta gtgatttaga
    90961 cattttagca tttccatcta aaccaggcaa acgccctgct ctctcatttt ctggataaat
    91021 accttccggc tctaccaaga catcacagtt atatgcattg ttaaaagaac gaacaatttc
    91081 acgagtttgc tcaatcattg gtttctgatc tgtcccaaca ggaacataat tagccttgaa
    91141 agctgtgata tcagctgctt gagcgattgg atagaccaag aatcctgtcg gaatgctttc
    91201 tccaaatcct ttctgagaaa tctctgtctt gactgttgga tttcgctcca aacgtgctaa
    91261 cgaaactaga ttcatataat acatagacaa ctcagccaac tctggaatct ggctttgaat
    91321 aaaaatagtt gacttatttg gatccaatcc aactgcaaga taatccaaag ccacatttcc
    91381 gatagactct acaatggttt gaggatcttt ggcatgatct gtcaaggctt gttggtcagc
    91441 caagaacaca aacatatcat acttatcctc ttcctgtaat aatactcgat ttttgagact
    91501 tccaacataa tgtccaatat gcaattttcc tgttggacgg tctcctgtta aaataatggg
    91561 tttagtcatt ttgttctcct tcgatatagt cctttcaatt atagcatttt tttaatgaaa
    91621 taaccgtaat ttatcaaaat aaatcagcct tgctttttac agatttgtgt aaaggatact
    91681 gtaaatataa tttacacaaa attgacaaat aaaaatttga atatttctgt attttctagt
    91741 agaataaata tattacacat ataggagaaa aatattgctt acagtatctg atgtttcact
    91801 acgttttagt gatcgcaaac tttttgatga tgtcaatatc aaatttacag aaggaaatac
    91861 ttacggatta atcggtgcta atggtgccgg aaaatcaacc tttttaaaaa ttttagctgg
    91921 agatatcgaa cctactactg gtcacatctc tcttggtcca gatgaacgtc tctctgttct
    91981 tcgtcaaaat cactttgact acgaagatga acgtgccatt gatgtcgtta tcatgggaaa
    92041 tgaaaaactt tatagcatca tgaaagagaa agatgctatc tacatgaagg aagatttctc
    92101 agacgaggac ggggttcgtg ctgccgaact cgaaggagag tttgccgaac ttggaggttg
    92161 ggaagcagag agtgaagcct ctcaactact tcaaaaccta aacattccag aagaattaca
    92221 ctaccaaaac atgagcgaat tggccaacgg tgaaaaagta aaggttctcc tcgccaaagc
    92281 actttttggt aaaccagatg ttcttctctt ggacgagcct actaacggtt tggatatcca
    92341 atcgattact tggttagaag acttcttaat tgactttgat aacacagtta tcgtagtatc
    92401 ccacgaccgt cacttcttaa acaaagtttg tactcacatg gccgaccttg actttggaaa
    92461 aatcaaactc tatgtcggaa actacgactt ctggaaggaa tcttctgagc ttgctgctaa
    92521 attgctagca gaccgtaatg ctaaagcaga agaaaaaatt aaacaattgc aagaattcgt
    92581 tgctcgtttc tctgccaatg cttctaagtc aaggcaggca acatcacgta agaaaatgct
    92641 tgataagatt gagctagaag agattgtgcc atctagtcgt aaatatccat ttatcaactt
    92701 taaagcggaa cgtgagattg gtaatgatct cttgacagta gaaaatctaa ctgtaaagat
    92761 tgatggtgaa actatcttgg ataatattag tttcatcttg cgtccagatg ataagacagc
    92821 acttattgga caaaatgata ttcaaacgac tgcattaatt cgtgcaatca tgggagatat
    92881 tgactatgaa ggaactgtca agtggggagt tacaactagt caatcttacc taccaaaaga
    92941 taactcagct gattttgcag gaggagaatc aattcttgac tggttgcgtc aattcgcaag
    93001 taaagaagaa gatgacaata ctttcctacg tggcttcctc ggccgtatgc tcttctctgg
    93061 agatgaagtt aacaaacctg taaatgtctt gtcaggggga gaaaaagttc gtgtcatgct
    93121 ttcaaaactc atgctcttaa aatcaaatgt ccttgtactt gatgatccaa caaatcactt
    93181 ggacttggaa tctatctcaa gcttgaatga tggattgaaa aactttaaag aatcaatcat
    93241 ctttgctagc catgaccacg aatttattca aactttggct aaccatatca ttgtcttatc
    93301 taaaaatggc gtcattgacc gtatcgatga aacctacgat gaattcctag aaaatgcaga
    93361 agtacaagca aaagttaaag aactttggaa agactaaata aaacttcaaa actcagttgg
    93421 gttaaccaac tgagttttct atcattctac gaggtaacat gaaatcattt ttaaaaacat
    93481 atcgaaccta ttttatttct ttcatcattc ctgtagtgat tatgtctgga gtatatctat
    93541 ctcaaggtat ctactggaat agcgacaact ctcctctatt aggagatggc tttcatcaat
    93601 acgttatttt tgatgtagcc ttacgaaata tcctacatgg aaatagtagt ctgttttaca
    93661 cctttacaag tggtctaggg ctaaacttct atgccctatc tagttattac ttgggtagtt
    93721 ttctcgcgcc tctagtttac ttttttgatc taacgaatat gccagatgct gtctatctga
    93781 ccactctctt aaaatttgga ttgattggtc tgtcaacctt ttttaatttg aataaattgt
    93841 ttcaatctat ccctcagact ttaaaactag ccttatctac ttcctatgct ctgatgagtt
    93901 tcactgtcag tcaattagag ataaaaacct ggctagatgt ttttatcttg attcctttaa
    93961 ttataactgg tttacatcta ctgataactg aaaagaaact cctattgtac tttacaagtc
    94021 tgtcaatctt atttattcaa aattattatt ttggatatat gacagtattg tttcttattt
    94081 tctggtatct ctgtcaaatt tcgtgggact ttaagactcg aaaatcatct gttcttgatt
    94141 tcatagttat ctccttttta gctggtatgg ctagtttgat tatgactctt cccactctat
    94201 ttgatttaca gacacatggg gaaaaattga ctgaagttac aaagtttcaa actgaaagta
    94261 gctggtatct tgatctcttt gctaagcaat tcattggttc ctttgacaca acaaagtatg
    94321 gggccatccc aatgattttt gttggactat ttccctttat tttgaccatt ttatttttta
    94381 cgctgaaatc tattaagttt cacgtgaaac tcatatatgt aatattcttt gcatttctaa
    94441 ttgcaagctt ttacatagaa gctcttgact tattttggca aggcatgcat actccaaaca
    94501 tgtttttaca tcgctatgct tggattttct ctaccttgtt aatttacaca gcagcagaag
    94561 tcttaaagcg tctgaaagaa cttaaagtct ggaatttttt agtttcgctt tttcttgtag
    94621 tagcaggatt tttagctacc atctatctaa aatcgcatta ttctttttta acagatttga
    94681 atattctgct tactcttgaa tttttggttg tctattctct tttactcctt gcagttatca
    94741 aaaagtttat atctgtgaat ctatttgcca ttctaatctc tttatttata ctggttgaaa
    94801 tgagtttaaa tgcttcatct caaatggacg gaattgctaa ggaatgggga tttgcttctc
    94861 gaagtgctta tagtcgagat atcccagcta tggaatcttt ctcaacatat attggaaatc
    94921 aatttactcg tactgaaaaa ctacaaactc agacaggaaa tgacagtatg aaattcaact
    94981 acaatggaat ctctcaattt tcatctgttc gaaatcgttc atcaagctct actttagata
    95041 aacttggttt taaatcctct gggactaatc tcaatctccg atatgcaaat aatagtattt
    95101 tggctgatag tttatttggt atccagtaca atatctcaga cagtcctatt gataagtatg
    95161 gctttaaaga tatctatcaa aaagataatc ttaccctata tgaaaatcaa tactctcttc
    95221 cgattgcagt tgctagtcaa tctgtttaca atgatgtcaa gttcaatgaa cataccttgg
    95281 ataatcaggc ctcattttta aatcaacttg ctaacgtcaa ttttgattat ttttctccaa
    95341 taccttatga aaaaacagaa aaaatagaaa atactaatga tttgattagt gtcacaagtt
    95401 cttcaaatga agatgcagca atccagtatc aaattgaagt tccagaaaac agccaagttt
    95461 atctctcttt cataaacctt cacttttcta acgataaaca aaagaaggtt gacatacttg
    95521 taaatggtga aaaaaagact tttacaactg ataatgtctt ctccttcttt aatctaggat
    95581 atactaaaga gaaaaaaact ttcaatatca atgttagttt ccctggaaat tcacaagtat
    95641 catttgaatc tcctaccttc tatcgtttag ataccaaaac tttcaccgag gcaattcaaa
    95701 aaattaaaga acaacctgtc acagtatcaa cttctaaaaa caaggttttt gctacatatg
    95761 atgtccaaca agatacatct attttcttca ccattcctta tgacaaaggt tggtctgcct
    95821 accaagatgg taagaaaata gaaattaaac aagctcaaac tggatttatg aaagttgaca
    95881 ttcccaaggg gaaaggaact attacacttt ccttcattcc caatggtttt attactggag
    95941 caatctgttc ctttacttct ctcttactat ttggaatcta taatcacaga cgaaagtcat
    96001 ctaaggcata aaaaatcgac cagttaatcg gtcgattttt ttaatcttct tccattttct
    96061 tatgttgata ggctagcata cctaaaccag taaatagagc tagtatgaca gctaggaaaa
    96121 tgacttgttg atagagattg tttgtcgtaa tcccgaaact gaatagctca ttggtaacca
    96181 gggattaata gatctaaaga aatcatttgt caaagcaagt ggataagtac ctgcacttga
    96241 tgctaactgt agtaaaagca aaataagtga gaaaaaagct cctatacggc tattccacgt
    96301 tgctaaagtg gtcaccatag acatgaatac taaacttgtt aggatgatga gaataaatat
    96361 tctcatctca tgattagcag ttaaaccaat aagctgaact cctccatata ccaaaattcc
    96421 tgccaaaaca gctataatac catttatttc agctcaagat ttcaaccaag cccaacggct
    96481 ctctggatga cgtcctgaag gcaatttcgc aaatatcata tttgttgata ttgctgcaaa
    96541 aaaaagagca actgatatca tataaggagc tattgcgatt ccatttacag gaacttgatc
    96601 attgtctgtt tttgaaagat tgagtggatt tgacaaaatc tctgcatttt tagattctgt
    96661 tgatactgat ttgagttgat cactagcatt acctagtcct tgtcctaaag aagcaagtcc
    96721 tgtctgtaaa tcttccaatc cagaagttaa ctttgttcca ccttctgcta gtttcccaga
    96781 tccatctgcc aatttattag ctctattctc taatggagaa gcacctgaaa gtaactgact
    96841 ggatttgtct gctaattgcc cagatcctga ttgtaattaa ccaactcctg ctgtcaatct
    96901 agaagatttt tgtgtcaagg tgtttgagcc tgaaactagt ttatccaaac tacctgtcaa
    96961 ggtggcattt ttttcactta gttgacttgc gccctgagaa actttatcaa cacctgtagt
    97021 atatgcgttt acacctgatg caatcaactg actggcagga actaatttgc tagtaacagc
    97081 tccttgtatc tctgttaatc cacttgacaa tcctatcaaa gaagtagaag taataggtaa
    97141 tacttgatta gcttgatttt ttaaagtcga aagattagaa gattgatttt gtaagttttc
    97201 taaacttccc tgtaaacctt gtactaaagc tacaattgac tgagccgatt gaatactatc
    97261 agttgaattt tgagatacag aatcacttat cccagtttgt tgctcacttg tcaatgattg
    97321 ataagctgct gtcgattgaa tattggataa tgtagttgtt tttttagata aatcacttgg
    97381 taaagtcact accatatagt aatcgccatc ttccaatccc ttctttcctt cctcttcatc
    97441 tacaaaatga aaatccaagg ttttattttc ttttaaattg gacaccatgt cttttcctat
    97501 tgccatagta ttaccattat aggaagcctc tttatcatta tttacaactg ccacaggtaa
    97561 gtcagacaat tgcccatatg gatcccacat tgatgacaaa aatatgatat tgtacagagc
    97621 tggaataaga gaaatcccga tcatgacaat aataaaggtt gtttttttta aattgctttc
    97681 cattctttaa acatagtttc tcctttttta aacatattgt ctaaaatttt gatataatag
    97741 attatacatt aaaaaatcta aattacaaga taaaaaatct atttttagac atatagtcta
    97801 atttgtttac aaggaggaaa tatgcaagaa agtaacaaac gcttaaaaac aaagcgaact
    97861 attgaaaatg ctatggtaca attactgatg gaacagccat ttgataaaat ttctactgtc
    97921 aaattagtag aaaaagccgg aattagtcgt tccagcttct atactcacta taaggataag
    97981 tatgatatga ttgagcacta tcaaagcaag ctattccata catttgaata tatttttcaa
    98041 aaacatgctc atcacaaaag agacgctatt ttagaagttt ttgaatatct agagtcagaa
    98101 ccacttctgg ctgcccttct ttctgaaaat gggactaaag aaatccaaaa tttcttacga
    98161 aataaacttc atatcatgct tagtacagat ttacaaaagc gatttatgca actgaatcta
    98221 aataccactg aattagaata tagtagcatc tatctaactc atgcactttt tggtgtctgc
    98281 caaacttgga ttgcacatgg aaaaaaagaa agttctcaag aaataacaga cttccttatg
    98341 aaaatgcttg gtgatacaaa ttgatacaaa aagaggaaca cagctgtgtt cccttttatc
    98401 tatactccgc cagtaggact cgaacctacg acatcatgat taacagtcat gcgctactac
    98461 caactgagct atggcggata aaatagtccg tacgggattc gaacccgtgt taccgccgtg
    98521 aaaaggcggt gtcttaaccc cttgaccaac ggaccttcta tctgtagcag atataaccat
    98581 tatatcaatt tcttgctaat tgtcaatcac ttttgagatt ttttctctaa aatatctttt
    98641 aattttctaa tttttaatct tgaaatagga caacgatggt cttcatagaa aacaatttct
    98701 aagttttttc gatcaatttc tctgatattg cctatattta ccaaaaatga cttgtgagga
    98761 gaataaaatc gctgagtatg tttgtccttt tcctgaatat ctgtcatggt accataaaac
    98821 tcttttgcaa aattcttacc aataatgcgc aatttatgag atacccctgt tgtttcaata
    98881 tacaaaatat catggtaagg aatttttaaa tcatttccct tgtaattgta gtcgaaataa
    98941 tctacaacat cttcattttc aagtaacata ctcttcgtgt agaagatatt ttgctcaatt
    99001 ctcttcttaa acatctcatc attgatatcc ttatcaacaa aatctagggc tgatacctgg
    99061 tatttatagg ttagagtcgc aaactctgat cgactagtga taaagacgat aatagcgtaa
    99121 ggattgtaat gacgaatgag ctgagccact tcaaatccct ttttctcaat tccatgaata
    99181 tcgatatcta ggaaataaag ctgatttact tcatcatttt caatgtattc ttcaaattca
    99241 cggacttttc ccgttgtctt gtatgatatt ggaatattcg attctttcga aatttcatcc
    99301 aatattctct ctagtctcac ttgatgttca ataacatctt ctaaaattaa aactttcatt
    99361 caaattccct cttaaatcta atgatttgtc taaatgtact gccttccatc tctgtttcta
    99421 aaataatatt gttgtactta tctagtagtt ctttcacatt atttaatccg actccgcgat
    99481 ttcttccctt agtggagaat cctaaggcaa atagatctcc tgaaggagtc atcgtcattt
    99541 tacatgaatt ctgaatcaca ataactgttt cagtttccat cttaataact gctacttcca
    99601 tctgcttttt atagctatca gccgatcctt cgacagcatt attcaataaa acgctcatga
    99661 tacgaaccaa atccaatagt tcaattggaa gcttggtaat cgtatctttt acttccagtg
    99721 taaactctac accattattt cgagcataga caattgactg agcaaccaaa cttcgtaaag
    99781 ctgagtcttc tatgttgttc aaatcaaagt aagtgtactt atctgaacgc aatttatgat
    99841 ttgctttgac taaaacttca ttgtaaattc tgtcaatttc ctgtaaatta ccactgtcaa
    99901 ttgccatctg catgctgaca agcattccag cataatcatg tcgaaaacca cggatttcat
    99961 tatacagacc aacaatttca tctgtgtaat tctgtaaatg tttctgttca aatttcttct
   100021 gcttcaaagc aatctctttc tccatttgaa ctttatgaga attcattgca aagaaggtca
   100081 aaaggagaga gataaagaca atagatgaca aaatacttcc aaaactattc aaatgtttaa
   100141 tcgtacttac catatctgaa acgaaagata caatatgtag caatagtaaa gcaaaaaata
   100201 cttttttcaa gaaaggataa aggtagtcct cgtcaaaata ggctagttcc aaatggaaat
   100261 agtaaatgat ttttaatgta acaaaatagg ttaacaccgt cacaacgaaa aagaatggga
   100321 aatgatattg taaaacaaaa ttatctcctg ttatagagga gaaagttacg gacagaaagt
   100381 tatgagtgct ctcatataaa agagatagta gtaaacttag gaatagtcct ctatccctct
   100441 catactgttt catccatcga aaataggaat ataatcccaa aggaaataaa aatctttcaa
   100501 tccctaaccc atctaaatat agaatatata agggaaaatc aaatactatt tctgttagta
   100561 atgtataagc accaaaaacg aataattctt ttctatttat ttgaccttta caaataaaat
   100621 ggtaactgtg actaataatt aaaaaatgaa caataaccgt cccaaatcca aataaatcca
   100681 ttactctttc cccttatttc attacttttt tctttgtaaa ataaaatcac ggaagaattt
   100741 tgacaacctc atctccccac ctttaatctt ttgtaagtct ttttccttca aagctacaaa
   100801 ctgttccaat ttaactgtgt ttttcataat aaaatctcct aaaatgtttt ttcttgtaag
   100861 ctaacttaca aaaaccatta tacaaaatgg aatttcgttt tagataaaat tctctcaact
   100921 gtcatttttt tctcccaaag tgtacttttt taagaaaaaa gccgggaaaa ttcccagctt
   100981 tgctattata ttgatcccag caggattcga acctgcgacc gttcgcttag aaggcgaatg
   101041 ctctatccag ctgagctatg agacctaata caattattct accaaaaatt caattaaaag
   101101 tcaattttct atttatggta ggggaatccc tgctgaatcg taaaagcgcg atagatttgt
   101161 tcaacaagaa ctagtctcat taactgatgg ggtaaggtta ggcgaccaaa actgacagaa
   101221 agattggctc tattttttac agatgatgac aatcctaaac ttcccccaat aataaaagta
   101281 agagtagaaa atccttttat agaagtttct tctaactgct tactaaattc ttctgagaag
   101341 aaagttttcc cttcaatggc taacacaata acgaaatcac ggtcagcaat ttttgataaa
   101401 attctctgac cttctatttc taaaatcttt tgattttctg attcactggc cttatctggt
   101461 gttttttcat ctgataactc aatcatttca aacttagcaa atctagaaat tcgttttgaa
   101521 tactctgcga taccatcttt taaatacttt tctttcagtt tcccaactgt tacaacttta
   101581 attttcatga ctctattcta acatattctc tattttttca catcttattc acaaaataaa
   101641 aaatagattt caattaagaa aatcacagtt tcaaaagagt tatccacagt ttgtgtaaaa
   101701 cttttgtgtt taagttataa ttaagctagt cagtttatac tttcagtaat tcaaacatat
   101761 ggaggcaaat atgaaacatc taaaaacatt ttacaaaaaa tggtttcaat tattagtcgt
   101821 tatcgtcatt agctttttta gtggagcctt gggtagtttt tcaataactc aactaactca
   101881 aaaaagtagt gtaaacaact ctaacaacaa tagtactatt acacaaactg cctataagaa
   101941 cgaaaattca acaacacagg ctgttaacaa agtaaaagat gctgttgttt ctgttattac
   102001 ttattcggca aacagacaaa atagcgtatt tggcaatgat gatactgaca cagattctca
   102061 gcgaatctct agtgaaggat ctggagttat ttataaaaag aatgataaag aagcttacat
   102121 cgtcaccaac aatcacgtta taaatggcgc cagcaaagta gatattagat tgtcagatgg
   102181 gactaaagta cctggagaaa ttgtcggagc tgacactttc tctgatattg ctgtcgtcaa
   102241 aatctcttca gaaaaagtga caacagtagc tgagtttggt gattctagta agttaactgt
   102301 aggagaaact gctattgcca tcggtagccc gttaggttct gaatatgcaa atactgtcac
   102361 tcaaggtatc gtatccagtc tcaatagaaa tgtatcctta agatcggaag atggacaagc
   102421 tatttctaca aaagccatcc aaactgatac tgctattaac ccaggtaact ctggcggccc
   102481 actgatcaat attcaagggc aggttatcgg aattacctca agtaaaattg ctacaaatgg
   102541 aggaacatct gtagaaggtc ttggtttcgc aattcctgca aatgatgcta tcaatattat
   102601 tgaacagtta gaaaaaaacg gaaaagtgac gcgtccagct ttgggaatcc agatggttaa
   102661 tttatctaat gtgagtacaa gcgacatcag aagactcaat attccaagta atgttacatc
   102721 tggtgtagtt gttcgttcgg tacaaagtaa tatgcctgcc aatggtcacc ttgaaaaata
   102781 cgatgtaatt acaaaagtag atgacaaaga gattgcttca tcaacagact tacaaagtgc
   102841 tctttacaac cattctatcg gagacaccat taagataacc tactatcgta acgggaaaga
   102901 agaaactacc tctatcaaac ttaacaagag ttcaggtgat ttagaatctt gattgacatc
   102961 tatgtaaaga aagctttaca taagagaaaa gatgtgttag tgtagaatca tggaaaaatt
   103021 tgaaatgatt tctatcacag atatacaaaa aaatccctat caaccccgaa aagaatttga
   103081 tagagaaaaa ctagatgaac tagcacagtc tatcaaagaa aatggggtca ttcaaccgat
   103141 tattgttcgt caatctcctg ttattggtta tgaaatcctt gcaggagaga gacgctatcg
   103201 ggcttcactt ttagctggtc tacggtctat cccagctgtt gttaaacaga tttcagacca
   103261 agagatgatg gtccagtcca ttattgaaaa tttacagaga gaaaatttaa acccaataga
   103321 agaagcactc gcctatgaat ctctcgtaga gaaaggattc acccatgctg aaattgcaga
   103381 taagatgggc aagtctcgtc catatatcag caactccatt cgtttacttt ccttgccaga
   103441 acagattctt tcagaagtag aaaatggcaa actatcacaa gcccatgcgc gttccctagt
   103501 tgggttaaat aaggaacaac aagactattt ctttcaacgg attatagaag aagatatttc
   103561 tgtaaggaaa ttagaagctc ttctgacaga gaaaaaacaa aagaaacagc aaaaaactaa
   103621 tcatttcata caaaatgaag aaaaacagtt aagaaaacta ctcggattag atgtagaaat
   103681 taaactatct aaaaaagaca gtggaaaaat cattatttct ttttcaaatc aagaagaata
   103741 tagtagaatt atcaacagcc tgaaataagg ctgttctttt atttttttat ctcacaaggt
   103801 tatccactat gtttttcgat aaaaagctta ataaatcaat aatttcttct tttatcccca
   103861 acctgtggat aaagtttggt aacattgtgg attatttttc acagcttgtg gaaaattctt
   103921 gctatctatg gtaaaatatc tctagtatta aacttttaaa tagtaaagga ggagaaagga
   103981 ttgaaagaaa aacaattttg gaatcgtata ttagaatttg cacaagaaag actgactcga
   104041 tccatgtatg atttctatgc tattcaagct gaactcatca aggtagagga aaatgttgcc
   104101 actatatttc tacctcgctc tgaaatggaa atggtctggg aaaaacaact aaaagatatt
   104161 attgtagtag ctggttttga aatttatgac gctgaaataa ctccccacta tattttcacc
   104221 aaacctcaag atacgactag ctcacaagtt gaagaagcta caaatttaac tctttataac
   104281 tatagtccaa agttagtatc tattccttat tcagatacgg gattaaaaga aaagtatacc
   104341 tttgataact ttattcaagg ggatggaaat gtttgggctg tatcagccgc tttagctgtc
   104401 tctgaagatt tggctctgac ctataaccct ctttttatct atggaggacc aggccttggt
   104461 aagactcact tattaaacgc tattggaaat gaaattctaa aaaatattcc taatgcgcgt
   104521 gttaaatata tccctgccga aagctttatt aatgactttc ttgatcacct aagacttggg
   104581 gaaatggaaa agtttaaaaa gacctatcgt agtcttgatc ttttgttaat cgatgatatt
   104641 cagtcactca gcggaaaaaa agttgcaact caggaagaat ttttcaatac ctttaacgcc
   104701 cttcatgaca agcaaaaaca gattgtccta acgagtgatc gtagtccaaa acatctagaa
   104761 gggctcgagg agaggcttgt cacgcgtttt agttggggat tgacacaaac tatcacaccc
   104821 cctgactttg aaacacgtat tgccatttta caaagtaaaa cggaacattt aggctacaat
   104881 ttccaaagtg atactctaga atacctagct gggcaatttg attcaaatgt tcgagatctt
   104941 gagggagcca tcaacgacat cactttaatt gccagagtaa aaaaaatcaa ggatatcact
   105001 attgatattg ctgcagaagc cattagagcc cgcaaacaag atgttagcca aatgctcgtc
   105061 atcccaattg ataaaatcca aactgaagtt ggtaactttt atggtgttag tatcaaagaa
   105121 atgaagggaa gtagacgcct tcaaaatatt gttttggccc gtcaagtagc catgtattta
   105181 tctagagaac taacagataa tagtcttcca aaaattggga aggaatttgg gggaaaagat
   105241 cataccacag tcattcatgc ccatgccaaa ataaaatctt tgattgatca agacgataat
   105301 ttacgtttag aaattgaatc aatcaaaaag aaaatcaaat aatttgtgga taacttttag
   105361 ttttttatct tttttatcca cattttttaa acaagctaaa aaacttgata tgacttgttt
   105421 aaaggctgtt ttccacagat ttcacagact ctattattac tattatcttt ctaatactaa
   105481 aaataaataa aggagaatcc atgattcatt tttcaattaa taaaaattta tttctacaag
   105541 cattaaatac tactaagaga gctattagtt ctaaaaatgc cattcctatt ttatcaacag
   105601 taaaaattga cgtgaccaat gaaggtatta ctttaattgg ttcaaatggt caaatttcaa
   105661 ttgaaaattt tatttctcaa aaaaatgaag atgctggttt gttaattact tctttaggtt
   105721 cgatccttct tgaagcttct ttctttatca atgtagtatc tagtttacct gatgtaactc
   105781 ttgattttaa agaaattgaa caaaatcaaa ttgttttaac cagtggcaaa tcagaaatta
   105841 ccctaaaagg aaaagatagc gaacaatatc cacgaatcca agaaatttca gcaagcactc
   105901 ctttaatact tgaaacaaaa ttactcaaga aaattattaa tgaaacagcc tttgctgcaa
   105961 gtacacaaga gagtcgtccg attttaacag gtgtccactt cgtattgagt caacacaaag
   106021 agttaaaaac agttgcaaca gactctcatc gcctaagcca gaaaaaattg actcttgaaa
   106081 aaaatagtga tgattttgat gtcgtaattc ctagccgttc tctacgcgaa ttttcagcgg
   106141 tatttacaga tgatatcgaa actgtagaga ttttctttgc caataaccaa atcctcttta
   106201 gaagcgaaaa tattagcttc tatactcgtc tcctagaagg aaactatcct gatacagatc
   106261 gcttgattcc aacagacttt aacattacta ttacttttaa tgtggtaaac ttacgccagt
   106321 caatggagcg tgcccgtctt ttatcaagtg cgactcaaaa tggtactgtg aaacttgaaa
   106381 ttaaggatgg ggttgttagc gcccatgttc actctccaga agttggtaaa gtaaacgaag
   106441 aaatcgatac tgatcaggtt actggtgaag atttgaccat tagtttcaac ccaacttact
   106501 tgattgattc tcttaaagct ttaaatagcg aaaaggtgac cattagcttt atctcagctg
   106561 ttcgtccatt tactcttgtg ccagcagata ctgacgaaga cttcatgcag ctaattacac
   106621 cagttcgtac aaattaagtg aaagaggttg agcctggctc gcctctttta tgatataatc
   106681 gaaaaagaaa aggagagtag tatgtatcaa gttggaaatt ttgttgagat gaaaaaatca
   106741 cacgcttgta caatcaagtc aactggtaaa aaggctaatc gttgggaaat tacacgtgta
   106801 ggagcagata tcaaaataaa atgcagtaat tgtgagcatg ttgtcatgat ggggcgatat
   106861 gattttgagc gaaaaatgaa taaaattatt gactgagaac ccttagttag agggttagca
   106921 ctttatccct ttttgtgtta taatattagg gattgaaatg aaaacggaga atgagaaata
   106981 tggctttgac agcaggtatc gttggtttgc caaacgttgg taaatcaaca ctatttaatg
   107041 caattacaaa agcaggagca gaggcagcaa actacccatt tgcgactatt gatccaaatg
   107101 ttggaatggt ggaagttcca gatgaacgcc tacaaaaact aactgaaatg ataactccta
   107161 aaaagacagt tcccacaaca tttgaattta cggatattgc agggattgta aaaggagctt
   107221 caaaaggaga agggctaggg aataaattct tggccaatat tcgtgaagta gatgcgattg
   107281 ttcacgtagt tcgtgctttt gatgatgaaa atgtgatgcg cgagcaagga cgtgaagacg
   107341 cctttgtaga tccacttgca gatattgata caattaatct ggaattaatt cttgctgact
   107401 tagaatcagt gaacaaacga tatgcgcgtg tagaaaagat ggcacgtacg caaaaagata
   107461 aagaatcagt agcagaattc aatgttcttc aaaagattaa accagtccta gaagacggga
   107521 aatcagctcg taccattgaa tttacagatg aggaacaaaa ggttgtcaaa ggtcttttcc
   107581 ttttgacgac taaaccagtt ctttatgtag ctaatgtgga cgaggatgtg gtttcagaac
   107641 ctgactctat cgactatgtc aaacaaattc gtgaatttgc agcgacagaa aatgctgaag
   107701 tagtcgttat ttctgcgcgt gctgaggaag aaatttctga attggatgat gaagataaaa
   107761 aagagtttct tgaagccatt ggtttgacag aatcaggtgt agataagttg acgcgtgcat
   107821 cttaccactt gcttggattg ggaacttact tcacagctgg tgaaaaagaa gttcgcgctt
   107881 ggactttcaa acgtggtatg aaggctactc aagcagctgg tattatccac tcagactttg
   107941 aaaaaggctt tattcgtgca gtaaccatgt catatgaaga tctagtgaaa tacggatctg
   108001 aaaaggccgt aaaagaagct ggacgcttgc gtgaagaagg aaaagaatat atcgttcaag
   108061 atggcgatat catggaattc cgctttaatg tctaaaaatt aataaatggt gtcaattagg
   108121 ttggaaaaaa attccaaccc ttttggcttt tgaaaggaaa aataaatgac caaattactt
   108181 gtaggcttgg gaaatccagg ggataaatat tttgaaacaa aacacaatgt tggttttatg
   108241 ttgattgatc aactagcgaa gaaacagaat gtcactttta cacacgataa gatatttcaa
   108301 gctgacctag catccttttt cctaaatgga gaaaaaattt atctggttaa accaacgacc
   108361 tttatgaatg aaagtggaaa agcagttcat gctttattaa cttactatgg tttggatatt
   108421 gacgatttac ttatcattta cgatgatctt gacatggaag ttgggaaaat tcgtttaaga
   108481 gcaaaaggct cagcaggtgg tcataatggt atcaagtcta ttattcaaca tataggaact
   108541 caggtcttta accgtgttaa gattggaatt ggaagaccta aaaatggtat gtcagttgtt
   108601 catcatgttt tgagtaagtt tgacagggat gattatatcg gtattttaca gtctgttgac
   108661 aaagttgacg attctgtaaa ctactattta caagagaaaa attttgagaa aacaatgcag
   108721 aggtataacg gataaatggt gaccttatta gatttattct cagaaaatga tcagattaaa
   108781 aaatggcatc aaaatttaac agataagaaa agacaactaa tacttggttt atcaacatct
   108841 actaaggcgc ttgcaattgc aagcagttta gaaaaagaag ataggattgt gttattgacg
   108901 tcaacttatg gagaagcaga aggacttgtt agtgatctta tatctatctt gggtgaggaa
   108961 ctcgtctatc catttttggt agatgatgct cctatggtgg agtttttgat gtcttcacag
   109021 gaaaaaatta tttcacgggt tgaagccttg cgttttttga ctgattcatc taagaaaggg
   109081 attttagttt gtaatatcgc agcaagtcga ttgattttac cgtctcccaa tgcattcaaa
   109141 gatagtattg taaaaatctc agttggtgaa gaatatgatc aacacgcgtt tatccatcag
   109201 ttaaaggaaa atggctatcg aaaagttact caagtacaaa ctcagggcga atttagtctt
   109261 cgaggagata ttttagatat ttttgaaata tcccagttag aaccttgtcg aattgagttt
   109321 tttggtgatg aaattgatgg tatcaggtca tttgaagtag aaacacaatt atcgaaagaa
   109381 aataagacag aactcactat ctttccagct agtgatatgc ttttgagaga aaaggattat
   109441 caacgaggac agtcagcttt agaaaaacaa atttcaaaaa ctttatcacc tattttgaaa
   109501 tcatacctag aagaaattct ttcaagtttt catcaaaagc aaagtcatgc agattctcgg
   109561 aagtttttat ctttgtgcta tgataagaca tggactgtct ttgattatat tgaaaaagat
   109621 actccaatat tctttgatga ttatcaaaaa ttgatgaatc agtatgaagt atttgaaaga
   109681 gaattagcgc agtactttac agaagaatta cagaatagta aagcattttc tgatatgcag
   109741 tatttttctg atattgaaca aatctataaa aaacaaagtc cagtgacctt tttctctaat
   109801 cttcaaaagg gtttaggaaa tctcaaattt gacaaaattt atcaattcaa tcaatatcct
   109861 atgcaggaat ttttcaatca gttttctttt ctaaaagaag aaattgaacg atataaaaaa
   109921 atggattaca ccattattct gcagtctagc aattcaatgg gaagtaaaac attggaggat
   109981 atgttagagg aatatcagat taaattggat tctagagata agacaagtat ctgtaaagaa
   110041 tctgtaaact taatagaggg taatctcaga catggttttc attttgtaga tgaaaagatt
   110101 ttattgataa ctgaacatga gatttttcaa aagaaattaa agcgtcgttt tcgaagacaa
   110161 catgtttcaa atgcagagag attaaaagat tacaatgaac ttgaaaaagg ggactatgtt
   110221 gtccatcata tccatgggat tggtcaatat ctaggaattg aaaccattga aatcaaggga
   110281 attcatcgcg attatgtcag tgtccaatac caaaatggtg atcaaatttc tattcccgtg
   110341 gaacagattc atctactgtc caaatatatt tcaagtgatg gtaaagttcc aaaactcaat
   110401 aaattaaatg atggtcattt taaaaaggcc aagcaaaagg ttaagaacca ggtagaggat
   110461 atagctgatg atttaatcaa actctactct gaacgtagtc agttgaaggg ttttgctttc
   110521 tcagctgatg atgatgatca agatgccttt gatgatgctt tcccttatgt tgaaacggat
   110581 gatcaacttc gtagtattga ggaaatcaag agggatatgc aggcttctca cccaatggat
   110641 cgacttttag ttggggatgt tggttttgga aagactgaag ttgctatgcg tgcagccttt
   110701 aaagcagtca atgatcacaa acaggttgtc attctagttc cgacgacggt tttagcgcaa
   110761 cagcactata cgaattttaa ggaacgattc caaaattttg cagttaatgt tgatgtgttg
   110821 agtcgcttta gaagtaaaaa agagcagact gcaacacttg aaaaattgaa aaacggtcaa
   110881 gtcgatattt tgattggaac acatcgtgtt ttgtcaaaag atgttgtgtt tgctgatttg
   110941 ggcttgatga ttattgatga ggaacagcga tttggtgtca agcataagga aactttgaaa
   111001 gaactgaaga aacaagtgga tgtcctaacc ttgaccgcta cgccaatccc tcgtaccctc
   111061 catatgtcta tgctgggaat cagagatttg tctgttattg aaactccgcc gactaatcgc
   111121 tatcctgttc agacctatgt tttggaaaag aatgatagtg tcattcgtga tgctgtcttg
   111181 cgtgaaatgg agcgtggagg tcaagtttac tatctttaca acaaagttga cacaattgtt
   111241 cagaaggttt cagaattaca ggagttgatt ccggaggctt cgattggata tgttcatggt
   111301 cgaatgagtg aagtccagtt ggaaaatact ctattagact ttattgaggg acaatacgat
   111361 atcttggtga cgactactat tattgagaca ggggtggaca ttccaaatgc taatacttta
   111421 tttattgaaa atgcggacca tatgggcttg tcaaccttat atcagttaag aggaagagtc
   111481 ggtcgtagta atcgtattgc ttatgcttat ctcatgtatc gtccagaaaa atcaatcagt
   111541 gaagtctctg aaaagagatt agaagcgatt aaaggattta cagaattggg ctctggcttt
   111601 aagattgcaa tgcgagatct ttcgattcgt ggagcaggaa atcttttagg aaaatcccag
   111661 tctggtttca ttgattctgt tggttttgaa ttgtattcgc agttattaga ggaagctatt
   111721 gctaaacgaa acggtaatgc taacgctaac acaagaacca aagggaatgc tgagttgatt
   111781 ttgcaaattg atgcctatct tcctgatact tatatttctg atcaacgaca taagattgaa
   111841 atttacaaga aaattcgtca aattgacaac cgtgtcaatt atgaagagtt acaagaggag
   111901 ttgatagacc gttttggaga atacccagat gtagtagcct atctgttaga gattggtttg
   111961 gtcaaatcat gcttggacaa ggtctttgtt caacgtgtgg aaagaaaaga taataaaatt
   112021 acaattcaat ttgaaaaagt cactcaacga ctgtttttag ctcaagatta ttttaaagct
   112081 ttatccgtaa cgaacttaaa agcaggcatc gttgagaata agggattaat ggagcttgta
   112141 tttgatgtcc aaaataagaa agattatgaa attttagaag gtttgctgat ttttggagaa
   112201 agtttattag agataaaaga gtctaaggaa gaaaattcca tttgatattt ttcttctata
   112261 aaatagataa aaatggtaca ataataaatt gaggtaataa ggatgagatt agataaatat
   112321 ttaaaagtat cgcgaattat caagcgtcgt acagtcgcaa aggaagtagc agataaaggt
   112381 agaatcaagg ttaatggaat cttggccaaa agttcaacgg acttgaaagt taatgaccaa
   112441 gttgaaattc gctttggcaa taagttgctg cttgtaaaag tactagagat gaaagatagt
   112501 acaaaaaaag aagatgcagc aggcatgtat gaaattatca gtgaaacacg ggtagaagaa
   112561 aatgtctaaa aatattgtac aattgaataa ttcttttatt caaaatgaat accaacgtcg
   112621 tcgctacctg atgaaagaac gacaaaaacg gaatcgtttt atgggggggg tattgatttt
   112681 gattatgcta ttatttatct tgccaacttt taatttagcg cagagttatc agcaattact
   112741 ccaaagacgt cagcaattag cagacttgca aactcagtat caaactttga gtgatgaaaa
   112801 ggataaggaa acagcatttg ctaccaagtt gaaagatgaa gattatgctg ctaaatatac
   112861 acgagcgaag tactattatt ctaagtcgag ggaaaaagtt tatacgattc ctgacttgct
   112921 tcaaaggtga taaaatggaa aatttattag acgtaataga gcaatttttg agtttgtcag
   112981 atgaaaagct ggaagaattg gctgataaaa atcaattatt gcgtttacaa gaagaaaagg
   113041 aaaggaagaa tgcgtaaatt cttaattatt ttgttgctac caagtttttt gaccatttca
   113101 aaagtcgtta gcacagaaaa agaagtcgtc tatacttcga aagaaattta ttacctttca
   113161 caatctgact ttggtattta ttttagagaa aaattaagtt ctcccatggt ttatggagag
   113221 gttcctgttt atgcgaatga agatttagta gtggaatctg ggaaattgac tcccaaaata
   113281 agttttcaaa taaccgagtg gcgcttaaat aaacaaggaa ttccagtatt taagctatca
   113341 aatcatcaat ttatagctgc ggacaaacga tttttatatg atcaatcaga ggtaactcca
   113401 acaataaaaa aagtatggtt agaatctgac tttaaactgt acaatagtcc ttatgattta
   113461 aaagaagtga aatcatcctt atcagcttat tcgcaagtat caatcgacaa gaccatgttt
   113521 gtagaaggaa gagaatttct acatattgat caggctggat gggtagctaa agaatcaact
   113581 tctgaagaag ataatcggat gagtaaagtt caagaaatgt tatctgaaaa atatcagaaa
   113641 gattctttct ctatttatgt taagcaactg actactggaa aagaagctgg tatcaatcaa
   113701 gatgaaaaga tgtatgcagc cagcgttttg aaactctcct atctctatta tacgcaagaa
   113761 aaaataaatg agggtcttta tcagttagat acgactgtaa aatacgtatc tgcagtcaat
   113821 gattttccag gttcttataa accagaggga agtggtagtc ttcctaaaaa agaagataat
   113881 aaagaatatt ctttaaagga tttaattacg aaagtatcaa aagaatctga taatgtagct
   113941 cataatctat tgggatatta catttcaaac caatctgatg ccacattcaa atccaagatg
   114001 tctgccatta tgggagatga ttgggatcca aaagaaaaat tgatttcttc taagatggcc
   114061 gggaagttta tggaagctat ttataatcaa aatggatttg tgctagagtc tttgactaaa
   114121 acagattttg atagtcagcg aattgccaaa ggtgtttctg ttaaagtagc tcataaaatt
   114181 ggagatgcgg atgaatttaa gcatgatacg ggtgttgtct atgcagattc tccatttatt
   114241 ctttctattt tcactaagaa ttctgattat gatacgattt ctaagatagc caaggatgtt
   114301 tatgaggttc taaaatgagg gaaccagatt ttttaaatca ttttctcaag aagggatatt
   114361 tcaaaaagca tgctaaggcg gttctagctc tttctggtgg attagattcc atgtttctat
   114421 ttaaggtatt gtctacttat caaaaagagt tagagattga attgattcta gctcatgtga
   114481 atcataagca gagaattgaa tcagattggg aagaaaagga attaaggaag ttggctgctg
   114541 aagcagagct tcctatttat atcagcaatt tttcaggaga attttcagaa gcgcgtgcac
   114601 gaaattttcg ttatgatttt tttcaagagg tcatgaaaaa gacaggtgcg acagctttag
   114661 tcactgccca ccatgctgat gatcaggtgg aaacgatttt gatgcgcttg attcgaggaa
   114721 ctcgcttgcg ctatctatca ggaattaagg agaagcaagt agtcggagag atagaaatca
   114781 ttcgtccctt cttgcatttt aagaaaaaag actttccatc aatttttcac tttgaagata
   114841 catcaaatca ggagaatcat tattttcgaa atcgtattcg aaattcttac ttaccagaat
   114901 tggaaaaaga aaatcctcga tttaggaatg caatcttagg cattagcaat gaaattttag
   114961 attatgattt ggcaatagct gaattatcta acaatattaa tgtggaagat ttacagcagt
   115021 tattttctta ttctgagtct acacaaagag ttttacttca aacttatctg aatcgttttc
   115081 cagatttgaa tcttacaaaa gctcagtttg ctgaagttca gcagatttta aaatctaaaa
   115141 gccagtatcg tcatccgatt aaaaatggct atgaattgat aaaagagtac caacagtttc
   115201 agatttgtaa aatcagtccg caggctgatg aagaggaaga tgaacttgtg ttacactatc
   115261 aaaatcaggt agcttatcaa ggatatttat tttcctttgg acttccatta gaaggtgaat
   115321 caattcaaca aatacctgtt tcacgtgaaa catccataca cattcgtcat cgaaaaacag
   115381 gagatgtttt gattcaaaat gggcatagaa aaaaactcag acgtttattt attgatttga
   115441 aaatccctat ggaaaagaga aactctgctc ttattattga gcaatttggt gaaattgtct
   115501 caattttggg aattgcgacc aataatttga gtaaaaaaac gaaaaatgat ataatgaaca
   115561 ctgtacttta tatagaaaaa atagataggt aaaaaatgtt agaaaacgat attaaaaaag
   115621 tcctcgtttc acacgatgaa attacagaag cagctaaaaa actaggtgct caattaacta
   115681 aagactatgc aggaaaaaat ccaatcttag ttgggatttt aaaaggatct attcctttta
   115741 tggctgaatt ggtcaaacat attgatacac atattgaaat ggacttcatg atggtttcta
   115801 gctaccatgg tggaacagca agtagtggtg ttatcaatat taaacaagat gtgactcaag
   115861 atatcaaagg aagacatgtt ctatttgtag aagatatcat tgatacaggt caaactttga
   115921 agaatttgcg agatatgttt aaagaaagag aagcagcttc tgttaaaatt gcaaccttgt
   115981 tggataaacc agaaggacgt gttgtagaaa ttgaggcaga ctatacctgc tttactatcc
   116041 caaatgagtt tgtagtaggt tatggtttag actacaaaga aaattatcgt aatcttcctt
   116101 atattggagt attgaaagag gaagtgtatt caaattagaa agaataatct ttaatgaaaa
   116161 aacaaaataa tggtttaatt aaaaatcctt ttctatggtt attatttatc tttttccttg
   116221 tgacaggatt ccagtatttc tattctggga ataactcagg aggaagtcag caaatcaact
   116281 atactgagtt ggtacaagaa attaccgatg gtaatgtaaa agaattaact taccaaccaa
   116341 atggtagtgt tatcgaagtt tctggtgtct ataaaaatcc taaaacaagt aaagaaggaa
   116401 caggtattca gtttttcacg ccatctgtta ctaaggtaga gaaatttacc agcactattc
   116461 ttcctgcaga tactaccgta tcagaattgc aaaaacttgc tactgaccat aaagcagaag
   116521 taactgttaa gcatgaaagt tcaagtggta tatggattaa tctactcgta tccattgtgc
   116581 catttggaat tctattcttc ttcctattct ctatgatggg aaatatggga ggaggcaatg
   116641 gccgtaatcc aatgagtttt ggacgtagta aggctaaagc agcaaataaa gaagatatta
   116701 aagtaagatt ttcagatgtt gctggagctg aggaagaaaa acaagaacta gttgaagttg
   116761 ttgagttctt aaaagatcca aaacgattca caaaacttgg agcccgtatt ccagcaggtg
   116821 ttcttttgga gggacctccg gggacaggta agactttgct tgctaaggca gtcgctggag
   116881 aagcaggtgt tccattcttt agtatctcag gttctgactt tgtagaaatg tttgtcggag
   116941 ttggagctag tcgtgttcgc tctctttttg aggatgccaa aaaagcagca ccagctatca
   117001 tctttatcga tgaaattgat gctgttggac gtcaacgtgg agtcggtctc ggcggaggta
   117061 atgacgaacg tgaacaaacc ttgaaccaac ttttgattga gatggatggt tttgagggaa
   117121 atgaagggat tatcgtcatc gctgcgacaa accgttcaga tgtacttgat cctgcccttt
   117181 tgcgtccagg acgttttgat agaaaagtat tggttggccg tcctgatgtt aaaggtcgtg
   117241 aagcaatctt gaaagttcac gctaagaaca agcctttagc agaagatgtt gatttgaaat
   117301 tagtggctca acaaactcca ggctttgttg gtgctgattt agagaatgtc ttgaatgaag
   117361 cagctttagt tgctgctcgt cgcaataaat cgataattga tgcttcagat attgatgaag
   117421 cagaagatag agttattgct ggaccttcta agaaagataa gacagtttca caaaaagaac
   117481 gagaattggt tgcttaccat gaggcaggac ataccattgt tggtctagtc ttgtcgaatg
   117541 ctcgcgttgt ccataaggtt acaattgtac cacgcggccg tgcaggcgga tacatgattg
   117601 cacttcctaa agaggatcaa atgcttctat ctaaagaaga tatgaaagag caattggctg
   117661 gcttaatggg tggacgtgta gctgaagaaa ttatctttaa tgtccaaact acaggagctt
   117721 caaacgactt tgaacaagcg acacaaatgg cacgtgcaat ggttacagag tacggtatga
   117781 gtgaaaaact tggcccagta caatatgaag gaaaccatgc tatgcttggt gcacagagtc
   117841 ctcaaaaatc aatttcagaa caaacagctt atgaaattga tgaagaggtt cgttcattat
   117901 taaatgaggc acgaaataaa gctgctgaaa ttattcagtc aaatcgtgaa actcacaagt
   117961 taattgcaga agcattattg aaatacgaaa cattggatag tacacaaatt aaagctcttt
   118021 acgaaacagg aaagatgcct gaagcagtag aagaggaatc tcatgcacta tcctatgatg
   118081 aagtaaagtc aaaaatgaat gacgaaaaat aaccctgaga gaggctggag
//
LOCUS       DBERDS010000002        83602 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.002, whole genome shotgun sequence.
ACCESSION   DBERDS010000002 DBERDS010000000
VERSION     DBERDS010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 83602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.002"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..933
                     /locus_tag="ACL73E_000107"
                     /pseudo
     CDS             1..933
                     /locus_tag="ACL73E_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            1328..2191
                     /locus_tag="ACL73E_000108"
     CDS             1328..2191
                     /locus_tag="ACL73E_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS0800161.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVTCAGLTTSQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRFGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            2477..2710
                     /locus_tag="ACL73E_000109"
     CDS             2477..2710
                     /locus_tag="ACL73E_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800162.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            2732..3409
                     /locus_tag="ACL73E_000110"
     CDS             2732..3409
                     /locus_tag="ACL73E_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0800163.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWFYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            3421..4086
                     /locus_tag="ACL73E_000111"
     CDS             3421..4086
                     /locus_tag="ACL73E_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0800164.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTVLEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            4158..5384
                     /locus_tag="ACL73E_000112"
     CDS             4158..5384
                     /locus_tag="ACL73E_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0800165.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            5646..6302
                     /locus_tag="ACL73E_000113"
     CDS             5646..6302
                     /locus_tag="ACL73E_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGS0800166.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            6292..6615
                     /locus_tag="ACL73E_000114"
     CDS             6292..6615
                     /locus_tag="ACL73E_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGS0800167.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            6719..7549
                     /locus_tag="ACL73E_000115"
     CDS             6719..7549
                     /locus_tag="ACL73E_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0800168.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            7703..8557
                     /locus_tag="ACL73E_000116"
     CDS             7703..8557
                     /locus_tag="ACL73E_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS0800169.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            8657..10030
                     /locus_tag="ACL73E_000117"
     CDS             8657..10030
                     /locus_tag="ACL73E_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGS0800170.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVSMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            10023..11084
                     /locus_tag="ACL73E_000118"
     CDS             10023..11084
                     /locus_tag="ACL73E_000118"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGS0800171.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            11086..11778
                     /locus_tag="ACL73E_000119"
     CDS             11086..11778
                     /locus_tag="ACL73E_000119"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGS0800172.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(11808..12377)
                     /locus_tag="ACL73E_000120"
     CDS             complement(11808..12377)
                     /locus_tag="ACL73E_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS0800173.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPTPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            12512..13126
                     /locus_tag="ACL73E_000121"
     CDS             12512..13126
                     /locus_tag="ACL73E_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS0800174.1"
                     /translation="MGRFLDFVFNRFFLGMIATALFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            13104..14774
                     /locus_tag="ACL73E_000122"
     CDS             13104..14774
                     /locus_tag="ACL73E_000122"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0800175.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14786..16072
                     /locus_tag="ACL73E_000123"
     CDS             14786..16072
                     /locus_tag="ACL73E_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0800176.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            16124..16657
                     /locus_tag="ACL73E_000124"
     CDS             16124..16657
                     /locus_tag="ACL73E_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800177.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            16735..17205
                     /gene="nrdI"
                     /locus_tag="ACL73E_000125"
     CDS             16735..17205
                     /gene="nrdI"
                     /locus_tag="ACL73E_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGS0800178.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKRIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(17498..18760)
                     /locus_tag="ACL73E_000126"
     CDS             complement(17498..18760)
                     /locus_tag="ACL73E_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGS0800179.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIEKAG"
     gene            complement(19070..19528)
                     /locus_tag="ACL73E_000127"
     CDS             complement(19070..19528)
                     /locus_tag="ACL73E_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGS0800180.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(19525..19965)
                     /locus_tag="ACL73E_000128"
     CDS             complement(19525..19965)
                     /locus_tag="ACL73E_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0800181.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            20321..22270
                     /gene="mutL"
                     /locus_tag="ACL73E_000129"
     CDS             20321..22270
                     /gene="mutL"
                     /locus_tag="ACL73E_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGS0800182.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(22595..23062)
                     /gene="ribE"
                     /locus_tag="ACL73E_000130"
     CDS             complement(22595..23062)
                     /gene="ribE"
                     /locus_tag="ACL73E_000130"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGS0800183.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(23063..24268)
                     /locus_tag="ACL73E_000131"
     CDS             complement(23063..24268)
                     /locus_tag="ACL73E_000131"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGS0800184.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRIDDLIQFSKKHNIPLITIKELQEYRKAYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKIIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(24288..24923)
                     /gene="ribE"
                     /locus_tag="ACL73E_000132"
     CDS             complement(24288..24923)
                     /gene="ribE"
                     /locus_tag="ACL73E_000132"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGS0800185.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(24908..26008)
                     /gene="ribD"
                     /locus_tag="ACL73E_000133"
     CDS             complement(24908..26008)
                     /gene="ribD"
                     /locus_tag="ACL73E_000133"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGS0800186.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGSHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMTMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(26142..26256)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            26413..27006
                     /gene="ruvA"
                     /locus_tag="ACL73E_000134"
     CDS             26413..27006
                     /gene="ruvA"
                     /locus_tag="ACL73E_000134"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGS0800187.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKIAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            27016..27579
                     /locus_tag="ACL73E_000135"
     CDS             27016..27579
                     /locus_tag="ACL73E_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGS0800188.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            27576..28253
                     /locus_tag="ACL73E_000136"
     CDS             27576..28253
                     /locus_tag="ACL73E_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0800189.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(28390..29421)
                     /locus_tag="ACL73E_000137"
     CDS             complement(28390..29421)
                     /locus_tag="ACL73E_000137"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGS0800190.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(29676..30359)
                     /locus_tag="ACL73E_000138"
     CDS             complement(29676..30359)
                     /locus_tag="ACL73E_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGS0800191.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(30371..31315)
                     /locus_tag="ACL73E_000139"
     CDS             complement(30371..31315)
                     /locus_tag="ACL73E_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS0800192.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            31447..34278
                     /gene="uvrA"
                     /locus_tag="ACL73E_000140"
     CDS             31447..34278
                     /gene="uvrA"
                     /locus_tag="ACL73E_000140"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGS0800193.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            34271..35332
                     /locus_tag="ACL73E_000141"
     CDS             34271..35332
                     /locus_tag="ACL73E_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS0800194.1"
                     /translation="MNKRVQAFLVKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            35464..35862
                     /gene="spx"
                     /locus_tag="ACL73E_000142"
     CDS             35464..35862
                     /gene="spx"
                     /locus_tag="ACL73E_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGS0800195.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            35928..36497
                     /locus_tag="ACL73E_000143"
     CDS             35928..36497
                     /locus_tag="ACL73E_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGS0800196.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            36584..36850
                     /locus_tag="ACL73E_000144"
     CDS             36584..36850
                     /locus_tag="ACL73E_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGS0800197.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            36854..37273
                     /gene="ruvX"
                     /locus_tag="ACL73E_000145"
     CDS             36854..37273
                     /gene="ruvX"
                     /locus_tag="ACL73E_000145"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGS0800198.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            37289..37594
                     /locus_tag="ACL73E_000146"
     CDS             37289..37594
                     /locus_tag="ACL73E_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGS0800199.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            38054..39304
                     /locus_tag="ACL73E_000147"
     CDS             38054..39304
                     /locus_tag="ACL73E_000147"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS0800200.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            39388..39846
                     /locus_tag="ACL73E_000148"
     CDS             39388..39846
                     /locus_tag="ACL73E_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGS0800201.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQQVQQPAQQ
                     NTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESD
                     GDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            39992..41524
                     /gene="cls"
                     /locus_tag="ACL73E_000149"
     CDS             39992..41524
                     /gene="cls"
                     /locus_tag="ACL73E_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGS0800202.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            41782..43320
                     /locus_tag="ACL73E_000150"
     CDS             41782..43320
                     /locus_tag="ACL73E_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGS0800203.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMDVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            43440..45647
                     /gene="nrdD"
                     /locus_tag="ACL73E_000151"
     CDS             43440..45647
                     /gene="nrdD"
                     /locus_tag="ACL73E_000151"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGS0800204.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKGENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            45659..45799
                     /locus_tag="ACL73E_000152"
     CDS             45659..45799
                     /locus_tag="ACL73E_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800205.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            45843..46349
                     /locus_tag="ACL73E_000153"
     CDS             45843..46349
                     /locus_tag="ACL73E_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0800206.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGLWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVKR
                     YWIEVANE"
     gene            46342..46932
                     /gene="nrdG"
                     /locus_tag="ACL73E_000154"
     CDS             46342..46932
                     /gene="nrdG"
                     /locus_tag="ACL73E_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGS0800207.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            46929..47546
                     /locus_tag="ACL73E_000155"
     CDS             46929..47546
                     /locus_tag="ACL73E_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS0800208.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            47813..48121
                     /gene="rpsJ"
                     /locus_tag="ACL73E_000156"
     CDS             47813..48121
                     /gene="rpsJ"
                     /locus_tag="ACL73E_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGS0800209.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            48337..48963
                     /gene="rplC"
                     /locus_tag="ACL73E_000157"
     CDS             48337..48963
                     /gene="rplC"
                     /locus_tag="ACL73E_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGS0800210.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            48988..49611
                     /gene="rplD"
                     /locus_tag="ACL73E_000158"
     CDS             48988..49611
                     /gene="rplD"
                     /locus_tag="ACL73E_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGS0800211.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            49611..49907
                     /locus_tag="ACL73E_000159"
     CDS             49611..49907
                     /locus_tag="ACL73E_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGS0800212.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            49925..50758
                     /gene="rplB"
                     /locus_tag="ACL73E_000160"
     CDS             49925..50758
                     /gene="rplB"
                     /locus_tag="ACL73E_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGS0800213.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            50862..51143
                     /gene="rpsS"
                     /locus_tag="ACL73E_000161"
     CDS             50862..51143
                     /gene="rpsS"
                     /locus_tag="ACL73E_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGS0800214.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            51155..51499
                     /gene="rplV"
                     /locus_tag="ACL73E_000162"
     CDS             51155..51499
                     /gene="rplV"
                     /locus_tag="ACL73E_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGS0800215.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            51512..52165
                     /gene="rpsC"
                     /locus_tag="ACL73E_000163"
     CDS             51512..52165
                     /gene="rpsC"
                     /locus_tag="ACL73E_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGS0800216.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            52169..52582
                     /gene="rplP"
                     /locus_tag="ACL73E_000164"
     CDS             52169..52582
                     /gene="rplP"
                     /locus_tag="ACL73E_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGS0800217.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            52592..52798
                     /gene="rpmC"
                     /locus_tag="ACL73E_000165"
     CDS             52592..52798
                     /gene="rpmC"
                     /locus_tag="ACL73E_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGS0800218.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            52823..53083
                     /gene="rpsQ"
                     /locus_tag="ACL73E_000166"
     CDS             52823..53083
                     /gene="rpsQ"
                     /locus_tag="ACL73E_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGS0800219.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            53109..53477
                     /gene="rplN"
                     /locus_tag="ACL73E_000167"
     CDS             53109..53477
                     /gene="rplN"
                     /locus_tag="ACL73E_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGS0800220.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            53555..53860
                     /gene="rplX"
                     /locus_tag="ACL73E_000168"
     CDS             53555..53860
                     /gene="rplX"
                     /locus_tag="ACL73E_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGS0800221.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            53884..54426
                     /gene="rplE"
                     /locus_tag="ACL73E_000169"
     CDS             53884..54426
                     /gene="rplE"
                     /locus_tag="ACL73E_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGS0800222.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            54444..54713
                     /gene="rpsN"
                     /locus_tag="ACL73E_000170"
     CDS             54444..54713
                     /gene="rpsN"
                     /locus_tag="ACL73E_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGS0800223.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            54998..55396
                     /gene="rpsH"
                     /locus_tag="ACL73E_000171"
     CDS             54998..55396
                     /gene="rpsH"
                     /locus_tag="ACL73E_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGS0800224.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            55588..56124
                     /gene="rplF"
                     /locus_tag="ACL73E_000172"
     CDS             55588..56124
                     /gene="rplF"
                     /locus_tag="ACL73E_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGS0800225.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            56208..56564
                     /gene="rplR"
                     /locus_tag="ACL73E_000173"
     CDS             56208..56564
                     /gene="rplR"
                     /locus_tag="ACL73E_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGS0800226.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            56582..57076
                     /gene="rpsE"
                     /locus_tag="ACL73E_000174"
     CDS             56582..57076
                     /gene="rpsE"
                     /locus_tag="ACL73E_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGS0800227.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            57090..57272
                     /gene="rpmD"
                     /locus_tag="ACL73E_000175"
     CDS             57090..57272
                     /gene="rpmD"
                     /locus_tag="ACL73E_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGS0800228.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            57417..57857
                     /gene="rplO"
                     /locus_tag="ACL73E_000176"
     CDS             57417..57857
                     /gene="rplO"
                     /locus_tag="ACL73E_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGS0800229.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            57870..59180
                     /gene="secY"
                     /locus_tag="ACL73E_000177"
     CDS             57870..59180
                     /gene="secY"
                     /locus_tag="ACL73E_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGS0800230.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            59331..59969
                     /locus_tag="ACL73E_000178"
     CDS             59331..59969
                     /locus_tag="ACL73E_000178"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGS0800231.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            60086..60304
                     /gene="infA"
                     /locus_tag="ACL73E_000179"
     CDS             60086..60304
                     /gene="infA"
                     /locus_tag="ACL73E_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGS0800232.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            60329..60445
                     /gene="rpmJ"
                     /locus_tag="ACL73E_000180"
     CDS             60329..60445
                     /gene="rpmJ"
                     /locus_tag="ACL73E_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGS0800233.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            60463..60828
                     /gene="rpsM"
                     /locus_tag="ACL73E_000181"
     CDS             60463..60828
                     /gene="rpsM"
                     /locus_tag="ACL73E_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGS0800234.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            60846..61229
                     /gene="rpsK"
                     /locus_tag="ACL73E_000182"
     CDS             60846..61229
                     /gene="rpsK"
                     /locus_tag="ACL73E_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGS0800235.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            61272..62207
                     /locus_tag="ACL73E_000183"
     CDS             61272..62207
                     /locus_tag="ACL73E_000183"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGS0800236.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            62219..62605
                     /gene="rplQ"
                     /locus_tag="ACL73E_000184"
     CDS             62219..62605
                     /gene="rplQ"
                     /locus_tag="ACL73E_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGS0800237.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            62870..63136
                     /locus_tag="ACL73E_000185"
     CDS             62870..63136
                     /locus_tag="ACL73E_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGS0800238.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            63146..64483
                     /locus_tag="ACL73E_000186"
     CDS             63146..64483
                     /locus_tag="ACL73E_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGS0800239.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            64727..65419
                     /locus_tag="ACL73E_000187"
     CDS             64727..65419
                     /locus_tag="ACL73E_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0800240.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(65522..67167)
                     /locus_tag="ACL73E_000188"
                     /pseudo
     CDS             complement(65522..67167)
                     /locus_tag="ACL73E_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(67157..68248)
                     /locus_tag="ACL73E_000189"
                     /pseudo
     CDS             complement(67157..68248)
                     /locus_tag="ACL73E_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(68261..69382)
                     /locus_tag="ACL73E_000190"
                     /pseudo
     CDS             complement(68261..69382)
                     /locus_tag="ACL73E_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(69969..70745)
                     /locus_tag="ACL73E_000191"
     CDS             complement(69969..70745)
                     /locus_tag="ACL73E_000191"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGS0800241.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            70867..71613
                     /locus_tag="ACL73E_000192"
     CDS             70867..71613
                     /locus_tag="ACL73E_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0800242.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            71626..72606
                     /locus_tag="ACL73E_000193"
     CDS             71626..72606
                     /locus_tag="ACL73E_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGS0800243.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            72801..73121
                     /locus_tag="ACL73E_000194"
     CDS             72801..73121
                     /locus_tag="ACL73E_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0800244.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            73167..73475
                     /locus_tag="ACL73E_000195"
     CDS             73167..73475
                     /locus_tag="ACL73E_000195"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0800245.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            73492..74790
                     /locus_tag="ACL73E_000196"
     CDS             73492..74790
                     /locus_tag="ACL73E_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0800246.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            74941..77379
                     /locus_tag="ACL73E_000197"
     CDS             74941..77379
                     /locus_tag="ACL73E_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGS0800247.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            77398..78066
                     /locus_tag="ACL73E_000198"
     CDS             77398..78066
                     /locus_tag="ACL73E_000198"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGS0800248.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            78084..79172
                     /locus_tag="ACL73E_000199"
     CDS             78084..79172
                     /locus_tag="ACL73E_000199"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGS0800249.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            79627..82128
                     /gene="leuS"
                     /locus_tag="ACL73E_000200"
     CDS             79627..82128
                     /gene="leuS"
                     /locus_tag="ACL73E_000200"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGS0800250.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDELNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            82428..83121
                     /locus_tag="ACL73E_000201"
                     /pseudo
     CDS             82428..83121
                     /locus_tag="ACL73E_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            83133..83549
                     /locus_tag="ACL73E_000202"
                     /pseudo
     CDS             83133..83549
                     /locus_tag="ACL73E_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT        25327 a        15116 c        18177 g        24982 t
ORIGIN      
        1 cttccgacag attatgatga gaaaattggt agttttaata catatgaaat cgaacaaacg
       61 gtatcgaaga ttctgagggt aaaacctaat ggaaagatta tttgaaagtc aacagttccg
      121 atcggctttt caaacaaatt aaaaaggctg tttgatacaa aaaatatcat ttttgtccct
      181 gaatttttga gagaaggttg ttctatatat gataatttat atccaagtcg catagttgtt
      241 ggagatgaga cagttgaagg aagaaaaatt gcagagttgt tcctttcgat tagtactcat
      301 agtactgcca atattaaaaa tgttatgtta gtttctccta ctgaagcaga agcaattcag
      361 cttttttcta acacattctt agctctccgt gttgcttttt ttaatgaact agattttttt
      421 gctgagagga gaagtttaaa tgctgaagtt gtaataaaag gtgtttgttt agatccaaga
      481 attggaaatt tttataataa tccttctttt ggatttggag gatattgtct tcccaaagat
      541 actaaacaat taaaaaaaga atttatagaa ataaatgccc cagtgataga agcgattgat
      601 atttcaaaca caaatagaaa acagttcata gttaaacaaa tattggaacg aaagccaaag
      661 atagtaggaa tatataaatt ggggatgaaa tataattcag ataattacaa agagtcagct
      721 attttaagta taattaatga actattgatt gtcggtataa aaattttagt atatgaacca
      781 aatttaaacg ttagtataga taacgtaatt tttgaaaaga attttgaact atttacaaaa
      841 caaagtgatc taattgttgc aaatagatgg gataggggcc ttgaagctta taaagataaa
      901 gtttacacaa gggggatctg gataagagat taactattga tattaaaaag gcaataattt
      961 ataaaatttg tacaaaaaaa tgttaaattt tcacattttc atagtatact gtttaataga
     1021 aagtaggttc tttgtaaccg ctccattata aaatcctttc actcttccgg tatactatta
     1081 ggaaaaacat aactggagga tattttgagc tcacacctca tcgttccagt ggctgttccc
     1141 caagctcgtg tactgtccaa aaaagttaga cattctattt agaacgagga ttgagttctg
     1201 tattgtacaa ggctcggtcc ttttagagtc agcttaaggc tggctttttc aatcaccaaa
     1261 gtgtcagaat gttttgacaa aactataaaa acaatgatat actatataaa aaataggagg
     1321 tggtgagatg atcgagagaa tggaattggg agaattttac aaagaactgc gcctggctag
     1381 aaagctcaag cagtcagatg tgacttgtgc tggtctaaca acctctcagt tgtccaagtt
     1441 tgaactaggg cagtctatgt tgtctgcaga taagctcata ttagccatcc aagggatcaa
     1501 tatgaatttt gatgagtttg ggcacaagct caacaactat caagaatctc cacatatgcg
     1561 atttggtaga aaggttgtgg atcgctttgc tcatcaagat atagctggct tagagcaact
     1621 gttggaggaa gtcgagcaag aacagatggc agagacttat cgtcgtttga atgctattgt
     1681 aatcaaagat gccatccact cactagataa aagctaccca ctagcagagg aggatagcga
     1741 gtttttgacc acctatctct atgctatcga gtcttggacc tggtttgaac tctatctctt
     1801 ttgcaatact atgcccttct tgagcaatca agatctgatc tttttatcaa cctccttact
     1861 cgaaaaatcc aaagaattta aagagttagt acacaatcga ttgtatatga agcaaggact
     1921 cttaaatatc atctcagagc tcatggagcg caaacttttt tcttatatcc caatctttga
     1981 agccgagctg gagagtatgc tccgtccata cgatgttttt gagaaattat tgtggcagtt
     2041 tttaaagaag atgagcattt tccttcaaac taagggaagc aatcaaaaag agattgaaca
     2101 ctttatccaa tctctgcaag tattagaaaa tccacaatta atagcccttt ttgaattgcg
     2161 tttgcagcaa tacaaaaagc ttatcgatta gttagaaatg gcaaaataat aataatctca
     2221 gcaacgattt tcaataatgt taaaatttgt ttcttcatat ttctccactc ctcattagta
     2281 gtaactttat tataccagag aagtaatcaa attcaccaaa atcgcaaatc tgaaatttct
     2341 ataagaaaaa atatcaaata tgcgattttc taaaataagc caattttcgt gttatactgt
     2401 acttgtaaag cacttgaagc aaatcctagg tcgcagaagt ggtttacaaa tgaagataat
     2461 tgaaggagtg taaaagatgt taaatttaca atttgcagaa acaatggaat tgacagaagc
     2521 tgagttgcaa gatgttagag gaggcaacct cgtaaattct atgggaggtg gtggaagaag
     2581 tggtatatct ggttggggcg tcccaggaat ttaccctggt tggggcaatc aagggatgag
     2641 tcctaatcgt ggagcttttg attggactat agatttagca gatggattgt ttggccgccg
     2701 tagaagatag gctcttatag gagataatag gatgaagaaa atgaaagaag tgaaatttca
     2761 cctagcaact ggcttgttga ttttgactta ttacctcatt tttaatgtca catcagactt
     2821 agattttatg gttgctttgt ctgataatat gtactatgtg ttccaagttt tattggtact
     2881 tattctggga actatagcta caattgcttt tgtcaaaagt gaacattgga aagagtgtgg
     2941 tcgtttccag tttcgttggt tttacctggg tgttttcctt ctttcttttt tcttattgtt
     3001 cgtgtgggca aatctaacaa cctatatctt tcctcgtacc cagaatggaa gtacagtcgt
     3061 agaagtagcc accaatttaa caggaattag ctattttgtt acgcgaatac tttatactag
     3121 tattatcgca cctgtatcag aagaggttgt ttgtcgtggt cttttgatga caagtttatc
     3181 taaagttaag agatactatc ttgatgttct tgtttccgct gccatatttg gcgctatgca
     3241 tgttttgcag tatggttgga taacgacaga tttcataaag tattttggaa tgggcttgat
     3301 attttgtatg atgtttcgct acacccgatc catctattgg gctatagctc tgcatgcttc
     3361 atggaatagt ttcttactca ttgttacttt attggtattt ggatattaga aaggtgatat
     3421 atgaaaaaga taatctcaca ccgctacttt attatagttt ttctactagt tattgctgac
     3481 cagaagttca gtgttctagt tttacgcagc gaccttgtta ctgggctatc tgactttgcc
     3541 tattatctgt cggatatgat gttgaatttt cttgtggttt tatttgctct tattgctatg
     3601 atttggtcgg ggaaatggca gaaaatcaat agtagaaagt ttaaaggatc ctatcttttc
     3661 tattccttcc tagctctgct tgcttttgtt gtttggaatt tcgttacctt ttttcttttc
     3721 ccacctactc gaaatgaaat ttcttatcaa catgctgctc cgacttttac aggggctaca
     3781 gcatttttga tgtatttttt ctatcctgtg attgcaggtc ccatttttga agagataatc
     3841 catcggggat tggtgatgac agttctggaa aaaggaaaga aatgggggct agatgtactt
     3901 ggttccgctg ttttatttgg ggtctcgcac attagtaatc acggttgggt cttgacagac
     3961 tttgtcttct atatgggtgg aggtcttata tttgcagtct tatttagaat gacaaagtca
     4021 atttattggc ctattggact gcatatagtc tacaatggca ttggtcagct tttgatgtta
     4081 ctgtaatttt ggttgttagt agtatcgcgg tctatccttg gggaaagctt cccatttgaa
     4141 cttaagaagg agttgtgatg aaagtatttc ttcaaaatag agattttagg caattaacta
     4201 tcaaccagtg gatttcaacg cttggggata cgatttttta tctggccttc ctgaattatg
     4261 tggcagatgc atcttttgcc cctttggcga ttttactcat cacgatttca gaaaccctgc
     4321 cccaagttct acaaatcttt ctgggagttt tggcggattt tcaacatcat cgtgtcttga
     4381 aatacacagt cattagtttt gcaaaatttt tgctttactc tatagtgtct ttatcacttt
     4441 cagggcagtc cttttccttg ttattagtag catttatttg tctgattaac cttttgtctg
     4501 acacgttgag ttatttttca ggcgccatgc tcactccgat tttcattaga attattgggc
     4561 aagaccatct ggcagaagct attggattta aacagtcaac tgttagttta gtgaaaacaa
     4621 tcagtaatat tctaggagga gtcttattag gtattctatc catccagttt atttccttgc
     4681 tgaacgctct taccttttta atcgcatttt taggtatcct cttcataaaa actgacctct
     4741 tgaaagtaga aaaaacgatt aactatcaag aaggactctc tgtaaaatcc ttttgccagc
     4801 atttgctcca atcatcgaaa ttgatatgga atatgaataa ggtgctcttg gttttgttta
     4861 ttatctctac tagtcaagca gtgataaatg ttacagttcc tgtctctact ctatttttga
     4921 ggaatcaacc ctttttgaat ttacaaacag gtcaatctct tgccttgcta tccacttttg
     4981 aactgtcagc cctgattgtc ggaagccttg taagtggcta tctgcaacat accatttcca
     5041 taaaaacagc tctctatgcc tcacttgtca tccagttgct tcttctagta ggatttgcca
     5101 cagttcgttt tgactggatt ctcatcttta gtaccttgga tgcctttttc gcaggtgttc
     5161 tctctcctag attgcaagaa ctcgtcttta aacaaatacc tgaggagtca atgggagcag
     5221 ttcaatcttc tatcagtgcc attacggttg ttttacctag cttatttaca atatctttgg
     5281 taaccattgc tactagcttt ggaactctgg cagttagctt tgttttattg ctatttcttc
     5341 tagttgcctt tgttatgctt ctgaatattc gtgaaagtat ttagtggaga atttctataa
     5401 tatatgtttg agactggatt gccagtcttt ttatgatggt caaaatcaac agactttttt
     5461 ctcttttctg aatgtgttat agtagactga atctaaaata gtacgaaaca attgctaaaa
     5521 catttataga aattaatttt actttcccaa tcgatttgtt catatcttat ttcaatccat
     5581 tatattaaga caatatgagg agaaagatga aagaaaaagg attttaggag ggggtgcagg
     5641 cagtcatgcc aacggctctt ggttatgtca gtatcggcct ggcctgtgga attatcggtg
     5701 cgccctatgt gacacctgtt gagatgggct tgatgagtct ctttgtttat gctgggagtg
     5761 cccagtttgc catgttggca ctgattgtgg ttcaagctcc tgtggcagct attgctatga
     5821 cggtttttct aatcaacttg cgtctctttt tgttgagttt acacgcatcg acttatttcc
     5881 gtcataccag tctttggtac aatatcggta tgtctagtat cttgacagat gagacctatg
     5941 gcgttttgat gggtgaattg gcccatacag acaaggtaaa tcctatgtgg atgcacggaa
     6001 acaatcttaa cagctatgtg gcttggtttg tggggacagt agtcggaacg gctctgggtg
     6061 gcctgctacc aaatccagaa atctttggct tggattttgc cctggttggg atgtttattg
     6121 gtatttttgc ttcgcaattt cagattatgc aaagacggat tcctgtccgc aatctgctca
     6181 ttatcctagc agttgttgcg gtgtccttct ttttgctctt gacagtggtg tctcagtcac
     6241 tagctgttct gtttgcgacg ctacttggtt gtagcatggg ggtggtttta gatggtcagt
     6301 aagtatcttt tattagcagt tattttctct ggcttggtga cttggattct ccgtatgatt
     6361 cccttcatct tagtcaagta taagggcttg cctgcaatcg ttgagcgttt tttgaagttc
     6421 ttgcccgttt ccattatctt tgccttgatt ctttcaagcg tagtgacagg taaggttggg
     6481 agccttcctc aaattaaatg gctagacttc ttagccgtct ttccaacagc ttgggtagcc
     6541 tttcgctacc gcaatctagt cggtacggtt ctctttggag tagtcttgat tgccgtcttg
     6601 cgtttggtct tttaaataag tcataaagaa aacttatcac agagatagat atcatataat
     6661 ggcgtaatta ctttttttct gataagatta taaggtattc tattttggag gaaatgacat
     6721 gaaaaaaatc gttaaatact catctcttgc agcccttgct cttgttgctg caggtgtgct
     6781 tgcggcttgc tcaggtggtg ctaagaaaga aggacaagca gctagcaaga aagaaatcat
     6841 cgttgcaacc aatggatcac caaagccatt tatctatgaa gaaaatggcg aattgactgg
     6901 ttatgagatt gaagtcgttc gcgctatctt taaagattct gacaaatatg atgtcaagtt
     6961 tgaaaagaca gaatggtcag gtgtctttgc tggtcttgac gctgaccgtt acaatatggc
     7021 tgtcaacaat cttagctaca ctaaagaacg tgcggagaaa tacctctatg ccgcaccaat
     7081 tgcccaaaat cctaatgtcc ttgtcgtgaa gaaagatgac tctagtatca agtctctcga
     7141 tgatatcggt ggaaaatcga cggaagtcgt tcaagccact acatcagcta agcagttaga
     7201 agcatacaat gctgaacaca cggacaaccc aactatcctt aactatacta aggcagactt
     7261 ccaacaaatc atggtacgtt tgagcgatgg acaatttgac tacaagattt ttgataaaat
     7321 cggtgttgaa acagtgatca agaaccaagg tttggacaac ttgaaagtta tcgaacttcc
     7381 aagcgaccaa caaccgtacg tttacccact tcttgctcag ggtcaagatg agttgaaatc
     7441 atttgtagac aaacgcatta aagaactcta caaagacgga acgcttgaaa aattgtctaa
     7501 acaattcttc ggagatactt atctaccagc agaggctgat attaaataat ttcttgaaat
     7561 catccattct gagtaagatg ggtgatttct cagtttttag ggatatagtt ttaaactata
     7621 tatctgatta tctaataaca atttgtgaaa tcaaacaaat tgtgagatac tagtacggta
     7681 ttatttttaa ggagaaagaa tcatgaaaat caaaaaatgg cttggcctag cagcccttgc
     7741 tacagtcgca ggtttggctc ttgcagcttg cggaaactca gaaaagaaag cagacaatgc
     7801 aacaactatc aaaatcgcaa ctgttaaccg tagcggttct gaagaaaaac gttgggacaa
     7861 aatccaagaa ttggttaaaa aagacggaat taccttggaa tttacagagt tcacagacta
     7921 ttcacaacca aacaaagcaa ctgctgatgg cgaagtagat ttgaacgctt tccaacacta
     7981 taacttcttg aacaactgga acaaagaaaa cggaaaagac cttgtagcga ttggagatac
     8041 ttacatctct ccaatccgcc tttactcagg tttgaatgga agtgccaaca agtacactaa
     8101 agtagaagac atcccagcaa acggagaaat cgctgtaccg aatgacgcta caaacgaaag
     8161 ccgtgcgctt tacttgcttc aatcagctgg cttgattaaa ttggatgttt ctggaactgc
     8221 tcttgcaaca gttgccaaca tcaaagaaaa tccaaagaac ttgaaaatca ctgaattgga
     8281 cgctagccaa acagctcgtt cattgtcatc agttgacgct gccgttgtaa acaatacctt
     8341 cgttacagaa gcaaaattgg actacaagaa agcacttttc aaagaacaag ctgatgaaaa
     8401 ctcaaaacaa tggtacaaca tcattgttgc gaaaaaagat tgggaaacat cacctaaggc
     8461 tgatgctatc aagaaagtaa tcgcagctta ccacacagat gacgtgaaaa aagttatcga
     8521 agaatcatca gacggtttgg atcaaccagt ttggtaataa gaaacaggga ggtgggagag
     8581 agaattccac ctcttgcttt tgtatagagc acggagtgta aagaagacta ttcgttcata
     8641 gaaaggtaga gagaatatgg tttttcctag cgaacaagaa cagattgaaa aatttgaaaa
     8701 ggatcatgta gcccagcatt attttgaggt tttacgtacc ttgatttcta agaaatcagt
     8761 ctttgcccag caggttggac tcaaggaagt cgcaaattat ctgggtgaga ttttcaagcg
     8821 tgttggagct gaagtggaga ttgatgagag ctatacagcg ccctttgtca tggcacattt
     8881 caagagttcg cgtccagatg ccaagacctt gattttctat aaccactatg acactgtgcc
     8941 agcggatggg gatcaggtct ggacagagga tccttttacg ctttcggtcc gcaatggctt
     9001 catgtatggg cgtggggttg atgacgacaa gggtcatatc acagctcgct tgagtgcttt
     9061 gagaaaatat atgcagcacc atgatgattt acctgtcaat atcagcttta tcatggaggg
     9121 agcggaggaa tcggcttcaa cagacctaga taagtatttg gaaaagcatg cagacaaact
     9181 ccgtggggcg gatttgttgg tctgggaaca agggaccaaa aatgccttgg aacagctgga
     9241 aatttctggt ggcaataagg ggattgtgac ctttgatgcc aaggtaaaaa gcgctgatgt
     9301 ggatatccac tcgagttatg gtggtgttgt ggaatcagct ccttggtatc tcctccaagc
     9361 cttacagtct cttcgtgctg cggatggccg tatcttggtt gaaggcttgt acgaagaagt
     9421 acaagagccc aatgaacgag aaatggcctt gctagaaact tatggtcaac gaaacccaga
     9481 ggaagttagt cggatttatg gattggagtt gcctctctta caggaggagc ggatggcctt
     9541 tctaaaacgt ttctttttcg agccagcgct taatatcgaa ggaatccagt ctggttatca
     9601 aggtcagggt gttaagacta ttttacctgc agaagccagt gccaagctag aggttcgtct
     9661 ggttccgggt ctagaaccgc atgatgttct ggaaaaaatt cggaaacaac tagacaaaaa
     9721 tggctttgat aaggtagaat tatactatac cttgggagag atgagctatc gaagcgatat
     9781 gagcgcacca gccattctca atgtgatcga gttggccaag aaattctatc cacagggcgt
     9841 ttcagtcttg ccgacgacag cggggacagg acctatgcat acggtctttg atgccctaga
     9901 ggtatcaatg gttgcattcg gtctaggaaa tgccaatagc cgagaccacg gtggagatga
     9961 aaatgtgcga atcgctgatt attacaccca tatcgaatta gtagaggagc tgattagaag
    10021 ctatgagtag agatattatc aagttagatc agatcgatgt gacttttcac caaaagaaga
    10081 gaaccattac agcggttaag gatgtgacca ttcacatcca agaaggggat atctacggaa
    10141 tcgttggata ttctggagca ggaaaatcaa cccttgtacg ggtgattaac ctcttgcaaa
    10201 aaccatctgc agggaaaatt accattgacg acgatgtgat ttttgatggt aaggtcacct
    10261 tgacggcaga gcagttgcgt cgtaaacgtc aagatatcgg gatgattttc cagcatttta
    10321 acctgatgag ccaaaagaca gcagaggaga atgtagcctt tgcccttaaa cactctggac
    10381 tcagcaagga agaaaagaag gctaaagtag ctaagttgtt ggacttggtt ggtttggcag
    10441 atcgtgctga aaactaccct tcacaactat ctggagggca aaaacagcgt gtggcaattg
    10501 cgcgtgcctt ggccaatgat ccaaaaatct tgatttcaga cgagtcaact tctgcccttg
    10561 accctaagac aaccaagcag attttggcct tgttgcaaga tttgaaccaa aaattaggct
    10621 tgactgttgt cttgattacg catgaaatgc agattgtcaa agacattgcc aaccgtgtgg
    10681 cggttatgca ggatgggcat ttgattgaag agggtagtgt gcttgaaatc ttctcaaacc
    10741 ctaaacaacc tttgactcaa gactttatct caacagctac aggtattgac gaagccatgg
    10801 tcaaaatcga gaagcaagaa atcgtggaac acttgtctga aaacagtctc ttggtgcaac
    10861 tcaagtacgc tggagcttca acagacgagc cacttttgaa tgaattgtac aagcattacc
    10921 aagtaatggc taatattctc tatgggaata tcgaaattct cgatggtact cctgttggag
    10981 aattggtggt ggtcttgtca ggtgaaaaag cagcgttggc aggtgcccaa gaagctattc
    11041 gccaagcagg tgtacaacta aaagtattga agggaggaca gtaagatgga atcattgatt
    11101 caaacctatt taccaaatgt ctataaaatg ggttgggctg gtcaggcagg ctggggaacg
    11161 gctatctact taactcttta tatgacagtt ctttccttca ttatcggagg cttcttgggg
    11221 ctagtggcag gtctctttct cgtcttgaca gcgccaggtg gtgtcttgga gaataaagtc
    11281 gtattctgga ttttagacaa aattacctca atttttcgtg cggttccctt tatcatcctc
    11341 ttggcaatct tgtcaccact ttctcacttg attgttaaaa caagtatcgg gccaaatgca
    11401 gcccttgtcc cactttcttt tgcagttttt gccttctttg cccgtcaggt gcaggttgtc
    11461 ttggctgaat tggatggcgg tgtcattgag gcggctcaag cgagcggagc gactttctgg
    11521 gacatcgtgg gtgtttacct atcagaaggt cttccagatt tgatccgtgt gacgactgtg
    11581 accttgattt cccttgttgg ggaaacagct atggccggtg cggttggagc tggtggtatc
    11641 ggtaacgtag ccatcgctta tggatttaac cgctacaatc acgatgtgac catcttggca
    11701 accatcgtta tcattttgat tatctttgca atccaattct taggagattt cttgactaag
    11761 aaattgagcc ataaataaaa aagagccgtg tggctctttt taactgatca gattttctgg
    11821 gcaaattttt tactcaaggc ttgtccaatc aaggcaccca ctagggctcc gatgacaata
    11881 cttgcgataa atagaaggac agttccaggg gttggagtga ccatgatacg gtcgatatat
    11941 tcttgggatt ttcctcttgc cagaagagta gccatatagg ctttgggcgc aatccacata
    12001 agcaagattg gtcctgttgt actaaaggcg aaaataatga aagaaaggaa gttctttgtt
    12061 ttgtccttgt attttcctaa atgagctact ccatctgcta ggaggccaca gataattcca
    12121 ggaaggaagg aaccagcacc gtgtttagtt cccaagaaaa agagggcaat gacaaggccg
    12181 atagtggtaa tggctccaaa gcgcggaact tttgcgacta ggatcatata gacgctaccg
    12241 ccgacaaggg cagtaaaggc aggcgcataa aacatgtttc cagtttggtc aaagagattg
    12301 cccaaaagga caccaatccc catgcagagg aagtaaagaa ctgcaaaaag cagtgtagtt
    12361 aagatagatt tcttcatgaa ttgtctcctg ataatttttt cacaattctc attttatcat
    12421 ggtttggtgg gattgtaaat ggatactaga agtttttgaa aacgcttgaa atatgatata
    12481 atggtttcat agttattttt aggggaatat catgggtaga tttttagact ttgtctttaa
    12541 tcgtttcttt ttagggatga ttgcgacagc cttattttgg ctattaactt tagcaggagg
    12601 gattatcctt ggtctagcgc cggctagtgc caccttgatg agcttatatg cagaacatgg
    12661 ttatagcttt cgggaataca gtttgaagga ggcttggtct ctttacaagc aaaattttgt
    12721 ctcaagcaac ctgattttct atagcttttt aggtgtgggt ctagttttga cctatggttt
    12781 gtatctcttg gtgcaattgc ctcatcagac cattgttcat ttgattgcga cccttttgaa
    12841 tgtcctagta gttgccctga tctttttggc ttatacagta tctttaaaat tacaagttta
    12901 ttttgccttg tcctatcgaa atagtctcaa attatccttg attggcatct ttatgagtct
    12961 agcagctgtg gctaaggttc tccttgggac tgtgctactt gtagcaattg gttattatat
    13021 gcctgccctg ctattttttg taggaattgg gatgtggcat ttctttatca gtgatatgtt
    13081 ggaacctgtc tatgaaatca tccatgaaaa attggcgaca aaatagaatg aagcagtttt
    13141 ggctacatac gcttctaaga acctatagtt cagtgatgat cattatcatt gcgagttttg
    13201 caatcttact ctcttacgct gactgggatt cacgtgaaaa ggaagcccag agagtagccc
    13261 agcgtgtaac tgctagaaca gtgagtgaaa ttgaatatta ccatagagag tcaacccaga
    13321 tagctcaggc tttagttgaa aatcaagctc gtatcgaggg aatctataaa tactttagcc
    13381 ttagcatgcc agactatttt tactggcaat tagagcggaa agcttcgcct tatatatcag
    13441 tctctctgta tgaaaatgtt gatgacctct atgttcgaaa tgattttgta actggggtgg
    13501 ccattgcttt tcaagattac aaggaagtct atgtttctac taaagacaaa cgtagtggag
    13561 aaaaaatcag ggctgaggat ttcaaaccag caggaaatag ttttgccatt ccggtgtcag
    13621 atccagtgtc agatcaagat ttaggagtga tttacatctc cttggatcct gctgttttat
    13681 accatgccat tgataatact agaggtcata ctccgatggc agtaacagtg acctcacctt
    13741 ttgatacgga gatttttcat attggtgaga cagttgataa ggagagtgaa aattggctag
    13801 ttggcttaac ttctcatgga tatcaggttc aggtggcagt tcctaaaaac tttgttttac
    13861 aaggaacagt gactagctct gctttgattg tgggtttgag ccttctcttt attgtcattc
    13921 tttatctgac tttgaggcag acttttgcta attaccaaaa gcaggtagtg gatttagtag
    13981 aatccattca agtcattgct caaggcgaag aggggcgtcg gattgacatt tccgagaaag
    14041 atcaggaatt gctcctaatc gcggagacga ccaatgatat gttggatcga ttggaaaaga
    14101 atatccatga tatttaccag ttagaactca gtcaaaaaga tgccaatatg cgggccttgc
    14161 aggcgcaaat caaccctcac ttcatgtata atacgctgga gttcttgcgc atgtacgcag
    14221 tcatgcagag tcaagatgag ttggcagata tcatttatga attcagtagt ctcttgcgta
    14281 acaatatttc cgacgaaaga gagaccctcc tcaaacagga attagaattt tgccgtaaat
    14341 acagctatct ctgcatggtt cgctatccca agtccattgc ctatggtttc aagatagatc
    14401 cagagttaga gaatatgaag attcccaagt ttaccttgca accgctggta gaaaattatt
    14461 tcgcgcatgg tgttgaccac aggcggacag ataatgtgat tagcatcaag gctcttaaac
    14521 aggatggttt tgtggaaatt ttggtggtcg ataatggtag aggaatgtcg gctgaaaagt
    14581 tggcaaatat ccgagaaaaa ttaagtcaga gatattttga acaccaagcc agctacagtg
    14641 atcaaaggca gtctatcggg attgtcaatg tacacgagcg ttttgtgctc tattttggag
    14701 accgctatgc cattacgata gagtctgcag agcaagccgg tgttcagtat cgtattacaa
    14761 ttcaagatga gtagaaaggg agaaaatgta taaagtatta ttagtagatg atgagtacat
    14821 ggtgacagaa ggtctgaagc gtttgattcc ctttgataag tgggatatgg aggtcgtcgc
    14881 aacagccagt catgccgatg aagctctaga atatgttcag gaaaatcctg tcgatgtcat
    14941 catttccgat gtcaatatgc cagacaaaac agggcttgat atgattcggg agatgaaaga
    15001 gatcttacca gatgctgctt atatcctgct ctcaggttac caggagtttg attatgtaaa
    15061 aagagcaatg aaccttagtg tggtggacta tttggtcaag cctgttgata aggtagagct
    15121 gggaaatctg ctggagaaga ttgcaggtca gctcggcgag agagggaaga aaagtcagac
    15181 tcttagtcaa gaattagacg aggctggatt tgttagttat ttaggggata aggagaattg
    15241 gtggataggt ctatccaagg aaaaacaagg ttccttcacc attccctact atgtcttggg
    15301 tcaagactgg cagattttca tttctgacca acccctagat ggtttagtcg ttacaccttt
    15361 tgaagctcct tatcaagaac actttgaacg ctggaagctg aatgctgaga aaaccctctt
    15421 ttacggctct gtaaatctgc agcagtctga gagtctcttt gcctattacg aaccgattta
    15481 tagggttatc attcagggaa atctcaatca aatcgtagaa gagttaaatc tcttggagaa
    15541 ggtagttctt gaaaatacgc cgcgtgttcc gattactaaa cagcttttta ttcagtttgt
    15601 catggatgtt ttccatttat ttgaacatct caaagctgat gacctgacag acatcgtcaa
    15661 aaccattcat gctattcaat ccttcgatga attggttcct tatatcaagg aaactctgag
    15721 cagctttttc ggtcaatacc gtatgaatga aaatgtggtc agtgtgctgg aagtcattgg
    15781 tcgtgattac caaaaagagc tttccctcaa ggatatcagt aaggctctct ttatcaatcc
    15841 tgtctatcta gggcagttga ttaagcgtga aaccgattcg acttttgcag agttactaaa
    15901 caaacaacgt attaaggctg cccaacaact tttgctttca actagtgaca gcatcgaaga
    15961 tatttgttat gctgttggtt acagtaacct tggatatttc tataaagttt tccgaaaatt
    16021 gtgcggaaaa tcgccaaaag cctaccgaaa acaggtagaa actatactat aaaatttgta
    16081 ttcctttaca aaaggtgcta taatattatc aggaggttct atcatgaaaa agaaaccaat
    16141 ttatctatgg gtcttgctaa tcttgtctgc ccttatttca gttccgtctc tgtttggaat
    16201 tgtgagtccc ttgcctagta aagaagccct tcgtgctgct cagaaacaag ttgcaggggt
    16261 caatgctcag caattagaag accagcttaa ttatacctat agagtagcag aagcatctca
    16321 ttctattttt aatgttgctt tgattgtgct atctactatt ttagtggtcg tagcgattgt
    16381 cttccttgtt cgtaaaaatt tgcaatatgc aaactatact tacgttggct atgttttgtt
    16441 agctattatt ggttcgattt atggctatgt tggtttacaa gacgctgtgc agttggttca
    16501 agatgagagc atgcgtttga cagtgagtat tggttcaaaa gctgttagca ttttctatat
    16561 cgtcatcaat gttctcttcc tagcccttgt cttctataag atgtggcgac aacagaaagc
    16621 cttggcagag gaagaggaaa cagaagagct tgcctaagta ttgacaaaaa agaactatca
    16681 agatacaatc ttggtagttg ttttttgatt atagataaaa tcatggaggt acatatgaag
    16741 acaatttctt tagtttatat tagtttgagt ggcaacactg aaagttttgt gacgcgcttg
    16801 aaagactatc tcttgtccca gtacaaaagg attgaggttc aaaagattca tatcaaggat
    16861 ttggtcaagg aaggcaaaaa tttctatgaa atggaccatc cctatgtcgc ttttttgccg
    16921 acctatctcg aaggtgggaa tggcgtggat aacggagatg ttgagatttt gacgacaccg
    16981 gtgggagatt ttattgccta tggtaacaat gctagtaagt gttttggtgt ggttgggtca
    17041 ggaaatcgta actttaataa ccaatactgc ctaacagcca agcaatacag tcaacgcttt
    17101 ggcttccctg tattggctga ctttgaaatg cgaggcatgc tggaagatat caaacatgtc
    17161 gcagctatta tcgcagattt gtatgagttg gaaaaggaga attaatactc aatgaaaatc
    17221 aaagagcaaa ctaggaagct agtcgcaggt tgctcaaagc acagctttga ggttgcagat
    17281 agagctgacg tggtttgaag agattctcga atagtataaa gttcttataa gaggtggttg
    17341 aagttgttca actgtttttt gagtataaac agtctttaag aacgtaaaaa agcataagtt
    17401 caggtcttca aaaccttgtt cttatgcttt ttatcataga aatatttgct gaattttctc
    17461 ttgaaatgaa accttatctt catctcgcgc ttgtccctta ccctgctttt tcgattgcga
    17521 gtgcgtagat aaagaagatg gcgaagccaa agaggaaaat caatcccgca atggcaaggt
    17581 gtttgagcca agaaggaaga tttttgtttt cacgcgttac caaggcgtaa ttcaaaagag
    17641 caaagaaagg tgttgtcagg aaagatccaa tcatggcaaa gcggagcatg gttgaaacct
    17701 gaccagcgaa gaacttgata atgacgatac cgatgatagc agtgatggtc atccagatgt
    17761 tcaaagattt acgattgtcc tctttttgac tgattagcag tcggagagat tcctgattaa
    17821 cgcgagaata gccatcgata acagttataa ctgttccaaa gatacagagg aaggcaataa
    17881 aggtaatcaa gtaacgggac cattcgccaa gaacagaggc atacatgccc acgaattgag
    17941 agatgtattt ggctgaagca gcttcaaccg cctgccctgt aggatactga atcagtgctc
    18001 ccagtgccac aaagaagacg gctaggatag ctgttccaat ataaccagtg ttaaagtcaa
    18061 acagagcgtc ttctgtgtta aagttgacgg tctttctctt ttcagctgac caaagtgaat
    18121 tgatggctga aatttcaata ggagccggca tccatcctag gagggagacg atgaagggca
    18181 gagctgccat ttgccaaggt gtcttctcga caaaatcaga actgtattct ggatgcttga
    18241 ccgctgctat gataactgcc agaacagtcg caatggttaa ggcagacata atccatttga
    18301 ccatgccgtc taaaagtttg tagcctccaa agagtagcat agcccaaatg attgcaacga
    18361 gaatgaggga ccactgagta atgctaagtc caatcattgg gaaggcactg gcgatgatag
    18421 ctgagcacag aatggcaaca ccagccgtgt tgaccatagc cgaaaagaca ttgaggataa
    18481 agaaaatcca gagatagagt tttccttttt cggcataacc ttcaaccaaa gtctttccag
    18541 tatcagctgt gtattcagca ccaaaacgga aaaatggata tttaaagaca ttggctaaga
    18601 tgaccaagag aagtagagac caaccgtaag aaccgccagc ttgagttgag gatacaatgt
    18661 gggaacctcc aacagcggca gttgccatta ggattccagg tcccattgct tttagcttgc
    18721 ttgcccaggt tgattgattt aaggaaatag cttgcgacat gataaatact cctttttgaa
    18781 ttttcagaat aatctgtata tgtaatctat attctacaaa aaattttgga aaaatgcaag
    18841 aatattttga aaaaagatag aaaatttaca aagaaaatct gaaataactg ttatgatata
    18901 gcatattgaa actagaatag tacacctttg cttctaaaac attgttagaa atcgatttga
    18961 ctgtcctgat cgatttatcc tgttcttatt tcatttcact atagtaaggt gcagcaggat
    19021 aaagaaaaac cgagaagttt ctttctcgga tttgcttatt atgaggttcc tattttctat
    19081 gctccaagag ttgattgatg tgatctactt ttttagcctc tcttttatag agaatagccc
    19141 agatgatgag atagacaatc gcaaactcga taatgagctg gaggtagaaa atccagtgga
    19201 aagggaacca accagcaaga gttgctagtg ggacaaagcc agccagcata aggaagaaat
    19261 gagtcagagt ggcacgaagc atgctccagt cacggctgaa taagcggttg ccaaagttga
    19321 agagcatacc gatggctgcc cagataagtg tgcagtagag caagaccagg gcaccgtgaa
    19381 cctgatgctg atccatcact tggccgatga gagagtaggg atttagtggt gcgtaggtat
    19441 ttggtgcata aatgagtgaa aagaggatgg agaggatgag gccgataaga acaccggcag
    19501 ctgcatcgtg aaatacttgt tttttcatag ttctaatttc tccttgatgg tttttagata
    19561 acggcgtgaa gagtaggtga agctttcgtt ttttaagaaa atttctacca gaccgtttgg
    19621 cgtgagcttg aggtgagaga tggaatcgat attgatgatt tctgattggg aaatttggat
    19681 aaaattgctt ggcaagagtt taagaacctg atagagtcgc aaatcaatgc tgtaggtctg
    19741 actcgcggtt tctgctagaa ccttccgatt ctctatatag aagcgctgaa tcttgccaat
    19801 ctcaactaga tagacctgat catcgatttt ccctttgatt ttttctcttt ggtccagatt
    19861 ttctgcgaac tcgatgactt tctggacttt atctgtcggc tgaggtgctt ggacaatcag
    19921 cttttcctcc tcgtaagtct cactaatctg tagttctact ttcataaatt tctctccttg
    19981 tttttcatac aaaattaatc tcacttcttg tacaccttta ttaatactct tcaaaaatct
    20041 cttcaaacca cgtcagcgtc gtcttgccat aggatagttg ttgactttgt cagttttatc
    20101 tacaacctca aaacagtgtt ttgaactgtc tgcgcctagc tttctagttt gctctttgat
    20161 ttttattgag tataccacta ttttactccc tctggcaagg gactttgtct atgtggaggg
    20221 attgggctcc tatgtggtgg agcttttctg ttctttctga aatatggtat aatagcacta
    20281 attaatttct aggaaaatag atacagaaag gggctgaaag atgtctcata ttattgaatt
    20341 gccagagatg ctggcaaacc aaatcgcggc tggagaggtc attgaacgtc ctgccagtgt
    20401 ggtcaaagag ttggtagaaa atgccattga cgcgggctct agtcagatta tcattgagat
    20461 tgaggaagct ggtctcaaga aggttcaaat cacggataac ggtcatggaa ttgcccacga
    20521 tgaggtggag ttggccctgc gtcgccatgc gaccagtaag ataaaaaatc aagcagatct
    20581 ctttcggatt cggacgcttg gttttcgtgg tgaagccttg ccttctattg cgtctgttag
    20641 tgtcttgact ctgttaacgg cggtggatgg tgctagtcat ggaaccaagt tagtcgcgcg
    20701 cgggggtgaa gttgaggaag tcatcccagc gactagtcct gtgggaacca aggtttgtgt
    20761 ggaggatctc tttttcaaca cgcctgcccg tctcaagtat atgaagagcc agcaagcgga
    20821 gttgtctcat atcattgata ttgtcaaccg tctgggcttg gcccatcctg agatttcttt
    20881 tagcttgatt agtgatggca aggaaatgac gcggacagca gggactggtc aattgcgcca
    20941 agcaatcgca gggatttacg gtttggtcag tgccaagaag atgattgaaa ttgagaactc
    21001 tgacctagat ttcgaaattt caggttttgt gtccttgcct gagttgactc gggctaaccg
    21061 caattatatc agcctcttca tcaatggtcg ttatatcaag aacttcctgc tcaatcgtgc
    21121 tattttggat ggtttcggaa gcaagcttat ggttggacgt tttccactgg ctgtcattca
    21181 catccatatc gacccttatc tagcggatgt caatgtgcat ccaactaagc aagaggtgcg
    21241 gatttccaag gaaaaagaac tgatgaccct ggtttcagaa gctattgcaa atagtctcaa
    21301 ggaacaaacc ttgattccag atgccttgga aaatcttgcc aaatcgaccg tgcgcaatcg
    21361 tgagaaggtg gatcaaacta ttctcccact caaagaaaat acgctctact atgagaaaac
    21421 tgagccgtca agacctagtc aaactgaagt agctgattat caggtagaat tgactgatga
    21481 agggcaggat ttgaccctgt ttgccaagga aaccttggac cgattgacca agccagcaaa
    21541 actgcatttt gcagagagaa agcctgctaa ctacgaccag ctagaccatc cagagttaga
    21601 tcttgctagc atcgataagg cttatgacaa actggagcga gaagaagcat ccagcttccc
    21661 agagttggag tttttcggac aaatgcacgg gacttatctc tttgcccaag ggcgagatgg
    21721 actttacatc atagatcagc acgctgctca ggaacgggtc aagtacgagg agtaccgtga
    21781 aagcattggc aatgttgacc agagccagca gcaactccta gtgccctata tctttgaatt
    21841 tcctgcggat gatgccctgc gtctcaagga aagaatgcct ctcttagagg aagtgggcgt
    21901 ctttctagca gagtacggag aaaatcaatt tattctacgt gaacatccta tttggatggc
    21961 agaagaagag attgaatcag gcatctatga gatgtgcgac atgctccttt tgaccaagga
    22021 agtttctatc aagaaatacc gagcagagct ggctatcatg atgtcttgca agcgatctat
    22081 caaggccaat catcgtattg atgatcattc agctagacaa ctcctctatc agctttctca
    22141 atgtgacaat ccctataact gtcctcacgg acgtcctgtt ttggtgcatt ttaccaagtc
    22201 ggatatggaa aagatgttcc gacgtattca ggaaaatcac accagtctcc gtgagttggg
    22261 gaaatattaa aagtataaaa aagtctggga aaaattttca aaatcagaaa aacgcataaa
    22321 atcaggtgtt caaaaacctt gattttatgc gttttatcat agaaatattt acttcatttt
    22381 ttcctaattc ttttcgaaac tctttttaaa cgacgtcagt tttatcagta atctcaaaac
    22441 agtgttttga gctaattttg ccagttttgt ctgtaacatc gaagttgtgt tttaccactc
    22501 tgcgactggt ttcctagttt gctctatgat tttcacagag tattaaattg cgattttgcc
    22561 aagtttcttt attcgtctaa aagtagagtc tgttctatgc gtctaatgta cgaattaggt
    22621 tgaccatttc aatagctcct tgtgcacact cagaaccctt atttcctgct ttagtaccag
    22681 ctcgttctat ggcttgttca attgtatctg tcgttagcac accaaacata acaggaattt
    22741 cgctatttaa actgatttgg gcgattccct tagatacctc gctacataca taatcataat
    22801 gacttgtatt ccctctaatg acagctccca agcagataat tgcatcatat tttttacttt
    22861 ttgccatttt tgatgcaatc agtggtattt caaaagctcc tggaacccag gctacctcta
    22921 tatctttctc gtttacattc tctcttttga gattatctag tgctccagat aataattttg
    22981 aagttataaa ttcattaaat ctcgctacaa caatacctat tttaatattg tttgctacta
    23041 aattaccttc ataagtgttc atttattttt cctccatatt taaaatgtga cccattcgat
    23101 ttttctttgt ttctaaataa aaactatcgt aaggattggc ttctatttcg attgatattc
    23161 tactggaaat ggtaattcca tatttttcta actgttcaac cttgtcagga ttatttgtca
    23221 gtaaatgaag tgactgaagt cccagatctt taagcatttg tgctccaata tgatattctc
    23281 ttaaatcacc ttcaaagcct aatgcaagat tggcatcaag cgtatccatg ccttgatctt
    23341 gtaaatgata ggcttttaat ttattgataa gtccaattcc tcgtccctcc tgtcgcaagt
    23401 aaagtaagac acccgaacca ttctcaacaa ttattttcat agctttatcg aattgctgtc
    23461 cacaatcgca acgtaaagag cctaaaacat ctcctgttaa acattcggag tggacccgac
    23521 ataatacatt ggcttcatcc tctatgtttc ccataataag agcaagatga tgttccccat
    23581 ttagtttatc tatatagcta attgctttga aattaccgta tctagtaggc atattgacag
    23641 ttgaaactcg ttctaccagc tgatcatatg cttttctata ttcttgtaat tctttgatgg
    23701 taattagtgg aatgttgtgt ttcttcgaga actgaattaa atcatctatt ctcatcattt
    23761 tgccatcatg attcattatt tcacaacata ggccacactc ttttagtcca gctaatttta
    23821 ataaatcaac agttgcttct gtgtgtccat ttctttctag aacaccacct ttttttgcaa
    23881 ttaaaggaaa catgtgtcct ggcctgcgaa aatcagaggg tgttatatct tcagctacac
    23941 acatacgtgc ggtcagtcct ctctcctcgg cagaaatacc tgtggtcgtt tctttataat
    24001 caattgaaac tgtaaaagca gtcttatgat tatctgtatt gttttcaacc ataggtgaaa
    24061 gcattaattg attagctaaa ctttcgctca taggcataca aattaatcct ttggcataag
    24121 tagccataaa attaacattt tctgttgtag ctgcttgtgc agaacaaatt aagtctcctt
    24181 cattttctct atccttgtcg tctataacaa gaacaagtcg tcccttctgc aatgcttcta
    24241 atgcttcttg tatttttcga tattccattg actgattatc ctttctgcta aaatccattt
    24301 tgatataata gttccttcga tatttctgat tttggagagt tatccatcag tttttgcaca
    24361 tatttaccta agatatcatt ttcaagattt actgtactcc cgacttgttt actcttaaga
    24421 atggtttgtt tcaaggtatg agggataaca gatactgaaa agtttacttt ggagacttta
    24481 gcgacagtca gactaatgcc gtcaattgta atagatcctt tttcaactat taaatctaaa
    24541 atttcttttt gtgtgttgat ttgataccat acagcattat catctttttt tattgacgag
    24601 atttttcctg taccatcaat gtgtcctgta acgacgtgac ccccaagtcg accgttgaca
    24661 gataaggctc tttctagatt cacctcactt ccatgtttta atagagtaag agctgttcga
    24721 ctccatgttt cattcattac atcaactgta aaggattgat gattgaaatg agtaactgta
    24781 agacagatac catttactgc tatactatcg cctaaatgga tatccgttaa tatttttgag
    24841 gctttaattg atagtttaca attacgagag tctttctgta ttctttcaac ttttccgatt
    24901 tcttcaatta ttcctgtgaa catggataaa tcacttcact ttctatgaga tagtcatttc
    24961 ctatttgaga aaaagcataa ggtttcaatc taatagcgtc atttggcaaa gaaatgcctt
    25021 cacctccgac aggaaacttg gcactgcctc caaaaatttt tggtgcaata tatattttca
    25081 gctcatcaac aatttgttgt tccaaagcac tccaattcat tagactgccc ccttctagaa
    25141 ctaggctatc aatctgcatg tttcctagat gttgcattaa actcgataag tctatatgat
    25201 tgcctttttt ctttatggaa agtatttcac agccatgatt ttgatatagc ttcattttat
    25261 ttttgtcttc agaggaagtg gcaatgtaag ttttaatatc atttgctgtt tttacgattt
    25321 tagaggtaag aggagttcgt aaatgtgtat cgcatatgat acggatagga tttttccctt
    25381 cctccaatct acatgtcagc aaaggatcgt cttgaataac agtattgact cccaccataa
    25441 ttgcactaac atggtgtcgt aactgatgca catgctttct tgcctcttct tcagtaatcc
    25501 atttggattg atttgtttta gtggctattt ttccatccat tgtcattgca tatttcataa
    25561 aaacataggg tacatgctgg gtaatatact ttctaaaact ttttattaag ttaagacact
    25621 cattttctaa aattccaaca gtaacttgaa gattattttc ctcaagtatc tttactcctt
    25681 ttccagatac aataggatta cagtctaggc ttccaatgac tactcttgta ataccactat
    25741 cgattatagc atctatacaa ggaggtgttt tcccgaagtg acaacagggt tcaagtgtta
    25801 cataaagcgt cgctccgaca ggggattctc tacagttttt aagagcattt ctctcagcat
    25861 gtgagccacc aaaaaactca tgataacctt gtccgatgat gtgattatct tttacaataa
    25921 ctgcgccgac cataggattg ggattgacgt aaccagcccc tttttgtgcc agttttattg
    25981 ctaatttcat atattttgaa tcgctcatct cactacctcc aaaaaaatat accttgaata
    26041 ggagactact caaggcatac aaaagaaaac ttatgcgatt aacaaaaatg ctctgaaatg
    26101 acaagtaatc atttcagagc acgcaaaaag cacaaatata cttttatctt ctttcatcca
    26161 gactatactg tcggctttgg aatttcacca aatcatgcct ttcggctcgt gggctatacc
    26221 accggtaggg aattgcaccc tgccctgaag atagttattc aattacagat gattatagta
    26281 cttaattttg aatatgtcaa cagataaata ccgattgttt ttgatatact gtatttgtga
    26341 taatcgattc tcgctcctcg gataaagaaa atatgatata ctagataaac gaaataagag
    26401 agaaggaaca ctatgtacgc atatttaaaa ggaatcatta ccaaaattac tgccaaatac
    26461 attgttcttg aaaccaatgg tattggttat atcctgcatg tggccaatcc ttatgcctat
    26521 tcaggtcagg ttaatcagga ggctcagatt tatgtgcatc aggttgtgcg tgaggacgcc
    26581 catttgcttt atggatttcg ctcagaggat gagaaaaagc tctttcttag tctgatttcg
    26641 gtctctggga ttggtcctgt atcagctctt gctattatcg ctgctgatga caatgctggc
    26701 ttggttcaag ccattgaaac caagaacatc acctacttga ccaagttccc taaaattggc
    26761 aagaaaacag cccagcagat ggtgctggac ttggaaggca aggtagtagt tgcaggagat
    26821 gaccttcctg ccaagatcgc agtgcaagca agtgctgaaa accaagaatt ggaagaagct
    26881 atggaagcca tgttggctct gggctacaag gcaacagagc tcaagaaaat caagaaattc
    26941 tttgaaggaa cgacagatac agctgagaac tatatcaagt cggcccttaa aatgttggtc
    27001 aaataggagc agagaatgac aaaacgttgt tcgtgggtca agatgaccaa cccactctac
    27061 atcgcctatc atgatgagga gtggggccag cccctccatg atgaccaagc gttgtttgag
    27121 ttgttgtgta tggaaaccta tcaggcaggc ctgtcttggg aaacggtact caacaaacgc
    27181 caagctttcc gagaagcctt tcatagctat caaattcact cagtcgcaga gatgactgac
    27241 actgaattgg aagccatgct ggagaatcca gctatcattc gaaatagagc caagattttt
    27301 gctacacgcg ctaacgccca agcctttcta cagttacagg cagagtacgg ctcttttgat
    27361 gcctatcttt ggtcttttgt tgaggggaaa actgtcgtta acgatgttcc tgattatcgc
    27421 caagccccag ctaaaacacc cttatctgag aaattagcca aagatctcaa aaaacgagac
    27481 ttcaagttca caggcccagt cgccgtattg tcttttctac aggctgcagg gctagttgat
    27541 gaccacgaga atgattgtga gtggaaaggt cttaaatgat gtctaacaaa aataagggaa
    27601 ttctgatttt tgcgattctc tatacagtcc tctttgtgtt tgatggcgtt aaattgctgg
    27661 cttctttaat gccatctgcc attgcaaatt atcttgttta tgtagtttta gctttatatg
    27721 gctccttctt gttcaaggat agattgatcc aacaatggaa ggagattaga aagactaaaa
    27781 gaaaattctt ctttggagtc ttaacaggat ggctctttct cattctgatg actgttgtct
    27841 ttgaatttgt atcagagatg ttgaagcagt ttgtgggact agatggacaa ggtctaaatc
    27901 agtctaatat tcaaagtacc tttcaagaac aaccactact gatagctgtt tttgcttgtg
    27961 tcattggacc tctggtagaa gaattatttt tccgtcaggt cttattgcat tacttgcagg
    28021 aacggttgtc aggtttacta agcattattc tggtaggact tgtttttgct ctgactcata
    28081 tgcacagttt ggctctatca gagtggattg gtgcagttgg ttacttaggt ggaggccttg
    28141 ccttttctat tatttatgtg aaagaaaaag agaatatcta ctatccccta cttgttcaca
    28201 tgttaagcaa cagcctctcc ttaatcattt tagctatcag tatagtaaaa tgaaatgaga
    28261 acaggacaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt ctagtttcaa
    28321 tatactgtaa tatgtgatga aaatgccagt aatgataccg agaaaaaagc tgagaaactt
    28381 ttcccagctt tatttgttat agtcaaagag aatgacttgt tcctgtgcat ctacatgagc
    28441 atggacccca aagggtacaa ttgctcttgg agttgcgtgg ccgacattca gattatagac
    28501 aatcgggata ttgctgtcaa tgatatccaa tagtgcctct ttatagtcgt catggaaagt
    28561 ttcatccata ggttttccga ccaagagtcc attgatgacc gcgaatatgc cagtgtcctt
    28621 taaagttagc aacatctttt tgaagtcttc tggcttaggc ttttcttcgc ttgtttcgag
    28681 caagaggatt ttcccttccc agtctgacaa gtcagggaaa agtttgtatt tttggcagag
    28741 ttccgtgcta tctgcgtatc gagagttgtc aaagatatcg tagagggatt cgaggcaacc
    28801 accgaggatt ttcccctcga actgagcact tccttgcaac aagtcaaaac ctgtatttgt
    28861 atgactgaca cgaggtgttc ccagggccgt gggactaaaa tcagttcgtt cctcatacca
    28921 aacgtcacta gggcggattt ctgaaattct tcccgtctca atcaattctt taaagtagtg
    28981 aaggctatag gctagcattt ctttgtctaa ttcacaaatg tctgctaaaa aggattgacc
    29041 ataaaaagtc ttgattccta atttatgcaa catgaggtgg ttcatggttg tatccgagaa
    29101 gccaagaaaa attttttgtt tgataacctt ttggagttgg tcattttcaa aaagataagg
    29161 tagcaagcga taggtatcgt ctccaccgat ggcacatagg atcatgtcga tgctatcatc
    29221 agaaaaggca tgaatcaaat cctctgcacg agcttcagga tggtccttga taaagtctaa
    29281 tccttttaac gaatggggca aaaagatggg attgagtccc agatccttga gacgttggat
    29341 acccaagtcc acttcgtgtt tgacaaaatc ctctccgata atgccactag ataaactaac
    29401 aataccaata gtagaaacca tatctcatcc tcctagaaat agattgagcc tattttatca
    29461 caaaatataa gagaaagcta tgtgggattt cagaagaata cttttaatac tcttcgaaaa
    29521 tctcttcaaa ccacgtcagt tttatctgca acttcaaagc tgtgctttga gcaacctgca
    29581 gctagcttcc tagtttgctc tttgattttc attgagtaca actcaaaaaa gtaagtgaaa
    29641 aagcaaccgc acctgcagtt gcttttatcg ttttcttatt cttgatagcg tgttggtcct
    29701 gcacttgcac tacggatatt caagcgtttc ttgagataga agcgaagggc taggagggct
    29761 gctccaataa tagctagtgg caatggatcc agtactgggt taaggctagc tggtaggaag
    29821 cttgttgcaa agaagacaag caaccaaagg aacatagaag ctaggataac tagtacagat
    29881 ttccagaaag gtggacgttg actgcgatcc atatctggtc catagtattg gtaaacaaag
    29941 tagtacatca agtagaaggc aaatccacca accagtccaa ctaatagaag agtaatcaat
    30001 ccatagccga aagcttgatc tgccgcaaag aaggttgtga gggcgctgac aagggcaaag
    30061 aggctagtga tgaaaagagc tgagtccata atcatcagtt ttggatcatc attttctttt
    30121 ggatgctctt tttcgtactg ctctttgaca gtgaagctat gagcccaatg agttggtgcg
    30181 ccgtataggg aacgggcagt tgtaccttta gattgctcct caaggatttg gggaatgact
    30241 tcctcaaaaa tagtctggat ttcagcgtct gttttcccat ctttgatgaa ttgttgggta
    30301 gcaatgtgga caaactcttg gtttttctta gttaattttt gtagatcaat ttgagacata
    30361 ggaactcctc ttagaaccat tttttatgga tgagatagag agtgagcgag acactcatag
    30421 caaaggcgat aaagacgatt aaccagaagg catttggctc tccgtttagg ggaatttcat
    30481 tatccttaaa gttcatcccg taggcagaaa agaccatggt tgggatggac atgacgatgg
    30541 tcacaagggc caaggttttc atgatgttgt tctggttgtt agaaatgata gaggcaaagg
    30601 tctctgtcat agaatgcaag acgtttccat aaatatctgc catctcgatg gcctgttggg
    30661 tttcaatcag ggtgtcttca agcaggtctt cgtcctcaag gtatttcttg atattgctgg
    30721 ttgaactggt caatttctta atcacgcgct catttgtttt gagggaggcc ttgaaataga
    30781 cgatagtttt ttccaattcc atgagctcaa tcaattcttc attacgagtt gattgatgca
    30841 gttgactttc gatttgttca ctcttgcggt cgattgaacg aagggctgtt aggtaaagct
    30901 ctgcattgcg ataaagaatt tgaaagataa aacgtgaacg catgaaggta tagaaattac
    30961 gcaatcgacg gttgataaag acatcaagga caggtagtgg ttccaaacac gtagtgataa
    31021 tggtttcctc agtgatgata ataccaagcg ggatggttac gtagtaggtg cggttatttc
    31081 tttcctccgt gaccggcacg tctacgataa tcagggtata ctcgtcttca atggtaatac
    31141 gagacatttc ttccgcatcg agcggtgctc gaaggtcggc aatatcaata tcgaaggtgt
    31201 tggcgatttc gagtgattca ttttgagtcg gattgacgag attgatccaa gtacccggtt
    31261 caagcgtatc gatctcttta aattcagttg ttgtagagag aaaaacttgt ttcatatccc
    31321 ttatcctttc tcatttttca gattttttca cactgtacta ttatactaca aaatcggcct
    31381 tttgggtaat agaatctcac tttttttggt ataatggtaa gcaataatgg actaggaaga
    31441 acaaagatgc aagataaaat tgtcattcat ggggcgcgtg cccataattt aaaaaatatt
    31501 gatgtggaga ttccgcgaga caagttggtt gtcgtgactg gcttgtcagg ttcagggaag
    31561 tccagtctgg cttttgatac tctctatgcg gagggacaac gtcgctatgt agagagtttg
    31621 tccgcctacg ctcgtcagtt cttgggaaat atggaaaaac cagatgtaga tgccattgat
    31681 ggtctcagcc cagctatttc catcgaccag aaaacgacta gtaaaaatcc tcgctcgacg
    31741 gtgggaacga cgactgaaat caatgactat ctgcgtctcc tctacgcacg tgtggggacg
    31801 ccttactgta tcaacggaca tggagctatc aatgcttctt ctgtggagca aatcgttgat
    31861 aaggttttgg agttacctga acgccagcgc ttgcagatct tggctcctgt catccgcaag
    31921 aaaaaaggcc aacataagag tgttatcgag aaggttcaga aagacgggta tgttcgtgtt
    31981 cgtgtggatg gggaagtcta tgatgtgacc gaagtgccag agttgtctaa gagcaagcaa
    32041 cacaatatcg atgtcgtggt tgaccgtatt gttatcaagg agggcattcg tagtcgtctc
    32101 tttgattcca ttgaggctgc ccttcgtatt gcagaaggtt atgtcattat cgacaccatg
    32161 gacgattcgg agttgctctt ctctgagcat tatgcctgtc cagtttgtgg ttttactgtc
    32221 ccagagttag agcctcgtct cttctctttc aatgctcctt ttggctcttg tagtgagtgt
    32281 gacggcttgg gcatcaagct ggaggtggat actgatttgg tagtgccaga tgccagcaaa
    32341 accttacgtg agggagcgct agcaccttgg aatcctatct catccaacta ctatccaaac
    32401 atgttagagc aggccatgaa agtctttgga gtggctatgg ataagccttt tgaggacctg
    32461 tcagaagaag ataagaactt gattctctat gggtcagatg gtaaggaatt ccatttccac
    32521 tatgagaatg aatttggtgg cgtgcgcgat atcgacattc cgtttgaggg agttatcaat
    32581 aatatcaaac gtcgttacca tgaaaccaat agcgattaca ctcgcactca gatgcgtctc
    32641 tacatgaatg agctgacctg cggaacctgt caaggctatc gtctcaatga ccaggccttg
    32701 tctgtccgtg tgggcggcca gcaagggcca catattggag aaatctcaga cctgtctatc
    32761 gctgaccact tggacttggt gagccagtta actttgtctg aaaatgaagc catcattgct
    32821 cgtcccattc tcaaggaaat caaggatcgt ttgaccttcc ttaataatgt gggtcttaac
    32881 tatctaaccc tgtcacgttc agcaggaacc ctttcaggtg gggaaagtca gcgcattcgt
    32941 ttggcaaccc agattggttc caacctatca ggcgtcctct atatcctaga cgagccgtca
    33001 atcggtcttc accagaggga caatgaccgc ctgattgcca gtctgaaaaa gatgcgtgac
    33061 ttgggcaata ctcttatcgt ggtggaacac gacgaagata ccatgcgtga agctgattat
    33121 ctgattgacg ttggtcctgg tgccggtgtt tttggtggtg agattgttgc agcaggtaca
    33181 cctaagcaag tggctcgcaa cagcaagtct atcacaggtc agtacttgtc aggcaaacgt
    33241 gtcatcccag taccagaaga gcgccgtgtc ggaaatggtc gttttattga agtgatagga
    33301 gcgcgtgaga acaacttgca aaatgtcacg gctcgctttc cactaggaaa atttatcgca
    33361 gtgacaggtg tgtcgggttc agggaaatcg actctaatca acagcattct caaaaaagcc
    33421 attgctcaga agctcaaccg taattcagac aaacctggta agtttaagac tattacaggg
    33481 attgagcatg tcgaccgttt gattgatatt gaccagagcc ctatcggacg gacgccgagg
    33541 tctaacccag ctacctatac aggagttttt gacgatatac gtgacctttt tgctcagaca
    33601 aatgaagcca agattcgagg ctacaagaag gggcgcttca gtttcaacgt caagggaggt
    33661 cgctgtgaag cttgctcagg tgacgggatt atcaagattg agatgcactt cttgccagat
    33721 gtttatgtgg cttgtgaagt ttgccacgga acccgctata acagtgaaac cctagaagtt
    33781 cactacaagg aaaagaatat ttcgcaggtc ttggatatga cggtcaacga tgcggtagaa
    33841 tttttccaac acattccgaa aattcaacgc aaactccaga ccatcaagga tgtagggcta
    33901 ggctatgtga ccttgggaca gccagctacc accctttctg ggggagaagc ccaacgtatg
    33961 aagttagcta gcgaactcca caaacgctcg acaggaaaat ctttctacat tctggatgag
    34021 ccgacgacag ggcttcatac agaggacatt gctcgcctgc tcaaggtttt agctcgcttt
    34081 gtagacgatg gcaatacagt cctcgtcatc gagcacaatc tggatgttat caagacggca
    34141 gaccatatca ttgacttggg acctgagggc ggtgtcggtg gtggaaccat catcgtaaca
    34201 ggaactccag aagaagtagc tgccaacgaa gccagctata caggacacta tttgaaagga
    34261 aagttacatc atgaataaac gcgtacaagc atttctagtt aaaatgcaag aaaaagaact
    34321 agatggtgtc atcatcaaca atcttaaaaa cgtctattat ttgactggtt tttggggctc
    34381 aaacggaaca gtctttatca gccgtgaccg tcaggtctta gtgacagact ctcgctatat
    34441 catcgcagct aagcaagaaa ccagtggttt tgagattgtg gctgatcgtg atgaattggc
    34501 tgtcattgca ggaattgtta aggacatggg cttgactcgt atcggttttg aagatgagat
    34561 ttcagtgtct tattaccacc gtatgcaggc agcttttgca ggtttggact tgtttccgca
    34621 aactcagttt gtggaaggtc ttcgtatgat taaggatgag gcagagattg cagcgattcg
    34681 caaggcttgt tctatctcag accaagcttt ccgcgatgcg cttgacttta tcaaaccagg
    34741 aaaaactgaa attgagattg ccaacttcct tgacttccgc atgcgtgagt tgggagcatc
    34801 tggcttatct tttgatacga tcctagctag cggtatcaat tcttctaaac cccatgccca
    34861 tccaatgcac aaaccagtgg agttgggaga agccattacc atggacttcg gctgtctcta
    34921 tgaccactat gtcagtgata tgacccggac tatctatcta gggcatgtta gcgatgagca
    34981 ggcagagatt tacaatacgg ttctaaaagc taaccaagcc ttgattgacc aagctaaggc
    35041 aggcttaggt ttccgtgact ttgacaaaat ccctcgtgat attatcattg aggcaggtta
    35101 tggcgactac tttactcacg gcattggcca cggtattggt ctggatatcc atgaggaacc
    35161 ctactttagc cagacttcta cagaaactat taagacaggt atggccttga ccgatgaacc
    35221 aggtatctat atcgaaggca aatatggcgt tcgtatcgag gatgatatcc tgattacaga
    35281 gacaggttgt gaattattga ccctagctcc aaaagagttg atagtcattt agttgtttgt
    35341 caagaaaaaa gtacgaaaat gacgaaaaaa gtcaaaaaaa attaaaaata ggtcgcaagt
    35401 cggatgtttt ttatggtata atagactaaa ctgatagtaa catgtagcga aaggggtagg
    35461 tacatgatta aaatttatac agtctcaagt tgtactagct gtaaaaaagc aaaaacctgg
    35521 ctcaatgccc accagttaag ttataaagaa caaaaccttg gtaaagaagg aattacgaga
    35581 gaagaattac tggatattct aaccaaaaca gataacggaa tagccagcat cgtttcgtct
    35641 aaaaatcgct atgccaaagc ccttggagtg gatattgaag atttgagtgt caatgaagtt
    35701 ctcaatctga ttatggaaac accgagaatt ttaaagagcc caatccttgt agatgaaaaa
    35761 cgcctgcaag ttggctacaa ggaagacgat attcgtgcct tcctaccacg ctctgtccgt
    35821 aatgtagaaa atgcagaagc acgtttacgt gcagctctat aaacatcaag gctgggagca
    35881 attcccagtc ttattctatt ttaatttcaa aaagaaagaa gaaagaaatg aaaaaaatag
    35941 ttcttgttag tctagctttc ctttttgtcc tggttggttg cggacagaaa aaagaaactg
    36001 gaccagctac aaaaacagaa aaggatacgc ttcagtcggc attgccagtt attgaaaatg
    36061 ccgagaagaa tacagttgta accaagactt tggtcttgcc caagtcagat gatggtagcc
    36121 agcaaactca aaccattaca tacaaggaca agactttttt gagcttaacg attcaacaaa
    36181 aacgtccagt ttctgatgag ttgaagactt atattgacca acatggagtg gaagaaactc
    36241 aaaaagctct tcttgaagcg gaggagaagg ataagtctat cattgaagct cgtaaattgg
    36301 taggtttcaa acttgaaaca aaactattga gcgcaacgga acttcaaaca acgactagtt
    36361 ttgattttca agttctggat gtcaagaagg cttcccagtt ggaacatctg aagaatattg
    36421 gtttggaaaa tcttttgaaa aatgaaccaa gcaaatatat ttcagacaga ttggcaaatg
    36481 gtgcgacaga acagtagaaa atccaaataa atagactgcc tgaattgtag aaggtaagga
    36541 attatgctat aatggtacta ttctaaggaa agagggtgtt agaatgggat ttactgaaga
    36601 aacagtacgt tttaaattgg acgattccaa taaaaaagaa attagcgaaa ctttgacaga
    36661 tgtttatgct tcgttgaacg ataagggtta caacccaatt aaccaaatcg taggttacgt
    36721 attgagtgga gaccctgcct acgttcctcg ttataataat gcacgaaatc aaatccgtaa
    36781 gtatgagcgt gatgaaatcg ttgaggaatt ggttcgctac tacctcaaag gacaaggagt
    36841 cgatctataa cctatgagaa ttatgggatt ggacgtcggt tcaaaaacgg taggggtggc
    36901 gattagcgat ccgcttggtt ttacagctca agggcttgaa atcatccaga taaatgaaga
    36961 acaaggccaa tttggttttg accgcgttaa ggaattggtt gatacttaca aggtggaacg
    37021 atttgtagtg ggcttgccta aaaacatgaa caatacaagt ggaccgcgcg tagaagctag
    37081 tcaagcctac ggagcaaagc tagaagagtt ttttggttta ccagtagact atcaggatga
    37141 acgcttgaca acagtggctg ctgagcgcat gttgattgaa caagcagata tcagtcgcaa
    37201 taagcgcaag aaagtcattg ataagttagc agctcagctg attttacaaa attatttaga
    37261 tagaaaattt taatataaag gagaggctat gtcacacgat cataaccacg accacgaaga
    37321 acgtgaacta atcacactag tagatgagca aggaaatgaa accttgtttg aaatcctttt
    37381 gacaattgat ggaaaagaag aatttggtaa aaactatgtt cttctagtac cagttaacgc
    37441 agaagaagac gaagacggac aagttgaaat ccaagcttac tcattcatcg aaaacgaaga
    37501 tggaacagaa ggcgaattgc aaccaatccc agaagactca gaagacgaat ggaacatgat
    37561 tgaagaagtc ttcaacagct ttatggagga gtgatacagt ctgggagact gtatcagccc
    37621 aactcccaga aatggggaag agttggaaca tccagtggat gtttttagcc cagttccttt
    37681 aaataagaga gaactggtaa gtccggggga cgtttttagc ctgacgctaa aaataaaaac
    37741 agtcagtaag ttcgggggat gttttagccc agctccttga aataagatag agctggtaag
    37801 tctgagaaac tgtatcagcc caactcccag aaatggggaa gagttggaac gtccagtgaa
    37861 catttttacc ccaactctta gaaattgaga agagttggaa catctagtgg atgtttttag
    37921 cccatattca cattcatagt agctagttat tagctaacca ggtaagaggt cgggacgaaa
    37981 atcctggcct tgtttttatt agtaaccata ctttaatgcg ataattgatt ggacttttgt
    38041 caaggagatg tgtatgtttg aagtagaaga atggctccat agtcggattg gtttgaattt
    38101 tcgatcaggt ttgggccgaa tgcagcaagc ggtggatttg ttaggaaatc ctgagcagtc
    38161 ttaccctatt atccacgtaa cagggactaa tgggaaagga tctaccattg cttttatgag
    38221 ggaattattt atggggcatg gcaaaaaagt tgcgaccttt acctcccctc atatcgtctc
    38281 tatcaatgac cgaatctgca ttaatgggca acctatagca gacgcagact ttatccgttt
    38341 gactgatcag gtcaaggaga tggagaaaac gcttctgcaa actcctgccc agttgtcctt
    38401 ttttgaattg ctgaccttag ttgcttttct ttattttagg gagcaagagg tggatttggt
    38461 tttattagaa gtgggaattg gtggcttact tgacacgacc aatgtggtaa ctggagagct
    38521 tgctgtcatc acctccattg ggcttgacca tcaagaaacc ttgggtgata gtctagaagc
    38581 aattgcagag cagaaagctg gtattttcaa ggctggtaaa aaggcagtga ttgcgaaatt
    38641 gcctccagaa gctagacttg tctgtcagaa aaaagctgaa tctttagctg ttgaccttta
    38701 tcaggcaggt caagattttt cagtgctgaa tggtgatttt tcaagctctt tactaaatct
    38761 ttcacagctg aacataggct tagaaggagc ctatcagcag gagaatgcgg ccttggcgtt
    38821 gcaaactttt cttcttttta tgggagaaag aaaggaagct attgatgaac aggctgtaag
    38881 aaaggccttg gaacagaccc attgggctgg tcgcttggag cgtattcgcc cacagattta
    38941 cttggatggt gctcataacc tccctgcctt gactcgcttg gttgagttta tcaaagaaaa
    39001 agagcaggaa ggctatcgac ctcaaatcct ctttggatcc ttgaaacgta aggattatca
    39061 agggatgttg ggttatctga ctgaaaattt acctcaagtg gaactcaaaa tgaccggctt
    39121 tgactatcaa gggtctttgg acgagacaga tgtaacaggt taccatgtaa ttccctctta
    39181 ccgagaattt atcagcagtt tcgaagaaag ggcagacgct caagacttgc tgttcgttac
    39241 agggtctctc tattttatct cagaagtacg gggctacctg ctggaccgtg agcagataaa
    39301 ttgaccccct tgtttgaact tgttatacta ggggaattgc tggttagaga aaatttctct
    39361 aaattggtag cagaaaggaa attcatcatg aaattaaaaa gattcacact ttctcttgct
    39421 tctctagcaa gttttagtct cttagtagct tgttcacaaa gagctcaaca ggttcaacag
    39481 cctgttgctc agcagcaggt ccaacagcct gctcaacaga ataccaatac tgcaaatgca
    39541 ggaggtaacc aaaatcaagc ggctccagta caaaaccaac ctgttgctca accgaccgat
    39601 attgatggga cttatactgg tcaggatgac ggagaccgta tcactttagt ggtaactgga
    39661 acgactggta catggactga gctcgaatct gacggggatc agaaagtcaa acaggttaca
    39721 tttgattcag caaatcaacg catgattatt ggcgatgatg tcaaaattta cactgtaaac
    39781 ggtaatcaaa tcgtcgtaga tgatatggat agagacccat cggaccaaat cgttttaact
    39841 aaataagact atgcaagtag aaagggctgg atttttcagc ctttttactt ttacctagaa
    39901 aataatcata aatacttgcc ttctaccgaa tacctgcgtt atactagtat caattacttg
    39961 tttttagcat tcaaactatc aaggagggga tatgaaatat aggaaatttc aattattgat
    40021 gtccaagtat ggctttagtc tttcgattat gctacttgaa ctttgtcttg tttttggtct
    40081 ctttctttat ttaggacgca tggctcccat tttatggatt actgtcctca ttctactgag
    40141 tatcatcaca atcatttcga tagtcaaccg taatacgact cctgagaata aggtaacctg
    40201 gttgttagta gcctttgtgc cagtatttgg tcccttgctc tatctgatgt ttggtgaaag
    40261 gcgattgtcc aaaaaagaaa tcaaacaact gaagaagcta ggctctatgc atttccaaga
    40321 agcaaatagc cagctactaa aagagaaatt aaaagaaagt gacaaggcag cttatggagt
    40381 catcaagtcc ttattgagta tggataccaa tgctgacatc tatgatcaaa ctgcctctac
    40441 attttttcct aacggagaag ctatgtggaa aaagatggta gaagatctta aaaaggctga
    40501 gaaatttatt ttcttggaat attacattat agaagaaggt ttgatgtgga atcgcatact
    40561 agatatacta gagcaaaagg tagctcaggg tgtagaggtt aagatgctct atgatgatat
    40621 cggctgtatg gctactttaa caggagatta tgcacatcga cttcgtcagc tgggcatcga
    40681 ggcccataaa ttcaataaag ttattcctcg tttgacagtg gcttataata acagagatca
    40741 tagaaaaata ttgattgttg atggtcagat agcctatact ggtggggtca atctggcaga
    40801 tgagtacatt aaccacgtcg agagatttgg ttattggaag gatagtggaa ttcgcttaga
    40861 cggactagca gtaaaagctc tgacacgctt atttttgacc acttggtaca ttaatcgagg
    40921 agaaattagt gattttgatc aatatcattt agaaaatcat tctatcccga gtgacggttt
    40981 aaccattcca tacggaagtg gacccaagcc aatttttcga gcgcaggtag ggaaaaaagt
    41041 ttatcagagt ttaatcaatc aagcaacaga atcggtctat attacgacac cttatttgat
    41101 tatagattat gatttaacag agacaatcaa aaatgcagct atgagagggg tcgatgttcg
    41161 aattatcacc ccttacatac cagataagaa gttcattcag ttagtcacga gaggagctta
    41221 tcccgacctt ctttctgctg gtgttcggat ttatgagtat agtccaggtt ttattcatag
    41281 taagcagatg ttggtagacg aagattttgc ggtggtgggg acaatcaatc tcgactaccg
    41341 gagcttggta caccattatg aaaatgcagt cttactctat aaaactcctt ctataaggga
    41401 aatcgcccga gattttcgaa atatatttgc agattctcag gaagtctatc ctcattctat
    41461 caaaacgagc tggtatcaaa agcttgtaaa agaaatcgcc cagctattcg cccctatctt
    41521 ataagaaatc tagaacttag gatacaaacc agacctattt ttcttgtctt ttacgaatag
    41581 aaagaaagag gaggggaatt catgctaact aaggaagaag tgaatgatat gattgagttc
    41641 aaacagacac atttacaccg ctttcgggaa attgaaacct ttgtgaaact atgcaaaaaa
    41701 tcactcaaac agccatcgca agctgacaat cctaggactt tttgatatac taagacagat
    41761 aaattgaaca ggagaaacga tatgagtgtg tatggtagag tagaagaagt tcataaggag
    41821 aatcgtgaac ctctagaata ccaaatcgaa caagaatcgc atcatcgtga atcaagtcgt
    41881 cttcctttgg tgaaaatttt actatggagt acgcttgtaa cggggataac tctaggagta
    41941 ccgctattac tcgacttaat gagtgcacaa gaagtgcagg atttttatgc aggttgggcg
    42001 cttcatcaga cagggaagat ttacagcgac tattatggaa gtcaaggttt gctttattat
    42061 ttgctgactt acgtgagtca gggcggattt ttctttgcca tctttgagtg gttagccttg
    42121 gtagcaggag gatttttcct ttttagatca gcggacacct tgacagagca aggagaccaa
    42181 gctggacatc tggtgactat tttttacatg ctagttacag gtcttgcttt tggtggaggc
    42241 tatgcgactc ttttagcgct tcctttctta ttcgcagcct ttagtttagt tgcggcttac
    42301 ctaagcaatc caagccatga taagggattt gtacggattg ggctagcttt ggcaggcgga
    42361 tttttctttg ctcccttatc atcgctcctg tttattgctg tagtgagttt aggcttgttg
    42421 gtctttaacc ttgggcatag acgctttgcg catgggtttt atcagtttct tgcagtggct
    42481 ttaggttttt cacttgtctt ttatccaact gcctactata gtgctgcaac aggaagtttt
    42541 ggggatgcga ttagtggtat tcgttatcct attgacagta ttcgctttga ttttacttct
    42601 aaaattttag agaatatgtt tttttatggc ttgttgtccc ttggtttggg atttgtggtt
    42661 tgtatctttt taggtctctt tcaatccaaa ccctttaaac tatacgtcat ttcggttcct
    42721 gcaagtcttg tggtaatttt aggtttgatt ttacttttct tttcacaaga gcctctgcac
    42781 gcttcttatt tgatggacgt cttccctgtt ttcctacttt tattggtaac caatattaag
    42841 agtcaacaga gggggcgtag tgctagaaga agccgaagag aaacgccagt tagcctatgg
    42901 agtcgtttct tcaaaggaaa tctatatctg ctagtttttg ggtttgtcta tcttttgtct
    42961 gttccttttt tgatgaagtt tgtcctttat ccagtacctt atcaagaacg taatcgtctt
    43021 gctgatttgg taaaagagga gacaaatacg gaagatgcta tctatgcatg ggatgatact
    43081 gcgactcttt atcgtaagag tgagcgcttg tcgccatcgg cgattttgtc cccgttgcac
    43141 tatacagcaa ctgaggaaaa tcgtaataag ttacttaatg acttgaaaga aaaacaacct
    43201 aaggtgattg tggtaaatga caaggtggta gtctggtctg aagtggaaac actcttaaaa
    43261 gaaaattacc aacaagtaaa gactgattac tcagagttta aagtctataa aattaaataa
    43321 ccaaatcaat atcttgtgta tttttaaaaa ttttaggatt tttaacacaa gatattgatt
    43381 tttcttttta gagtggtata atacttttta gaaagaacat tttagaaaag agcatgcgta
    43441 tgattgcact agaagaaaaa attacaattt tgccaactct cttcgtcgag aaacgagatg
    43501 ggagacgtgt tgtatttgat gtggacaaga ttgacaaggc tctccacaag gcggctgaca
    43561 aggttatgga tgtgacaccc ctggttgaaa aacgcctcaa tgatctgact gagcgaatta
    43621 ttacagaaat tcatagtcgc tttccacagg gaattaagat ttacgaaatt caaaatatcg
    43681 tagaacatga actccttgaa gccaaagaat atgcactggc tgaggagtat attacttatc
    43741 ggacacagag ggattttgag cgctcaaaag cgacggatat caactttagt attcataaac
    43801 ttctcaacaa agaccagaca gttgtcaatg aaaatgctaa taaagacagt gatgtcttta
    43861 acactcagcg tgatttgaca gcagggattg ttgggaaatc aatcggactg caaatgcttc
    43921 ctaagcacgt agccaatgcc caccaaaagg gggatatcca ctatcacgat ttggactaca
    43981 gtccctatac ccctatgacc aactgctgtt tgattgattt taagggtatg ttggaaaatg
    44041 gttttaagat tggaaatgca gaggtagaga gtcccaagtc tatccagact gcgacagcac
    44101 agatttctca aatcattgcc aacgttgctt ctagccagta cggtggctgt tcagctgacc
    44161 gtatcgatga aattttggcg ccttatgcag agaagaacta tcaaaaacat ctcaaagatg
    44221 cagaagagtg ggtattgcct gaaaaacggg aagattacgc ttggaagaaa acgcaaaagg
    44281 acatctacga tgccatgcaa tctcttgagt atgaaatcaa tactctcttc acttcaaatg
    44341 gacaaacacc ttttacttcg ctaggttttg gtctgggaac cagtcgtttt gaacgagaaa
    44401 ttcaaaaagc tattttaaac attcgcatca agggtcttgg ttcagaacac cgtacggcta
    44461 tctttcctaa acttattttc actctgaaaa gaggacttaa tttagaggaa ggaactccca
    44521 actacgacat caagcagttg gctcttgagt gtgcaaccaa acggatgtat ccagatgttt
    44581 tatcttacga taagattgtt gacttgacag gatccttcaa ggtgcctatg ggttgccgtt
    44641 ctttcctcca aggatggaag ggtgaaaatg gtgtagaagt caattcaggt cgcatgaatc
    44701 tgggtgttgt gacggttaat ctgcctcgta tcgctcttga gtctgaaggt gatatgaata
    44761 agttctggga aatcttcaac gagcgaatga atatcgcaga agatgctctt gtttaccgtg
    44821 tcgaacgcac taaagaggcg acaccagcaa atgctcctat tctttatcag tatggtgctt
    44881 ttggccatcg tctaggtaaa gaagaaagtg ttgaccagct ctttaagaat cgtcgtgcga
    44941 ccgtttcgct gggctatatc ggcttgtatg aagtagcgac agttttcttt ggtaacagct
    45001 gggaaagtaa tccagatgct aaggaattca cgctagacat cattcacgat atgaaacgcc
    45061 gtgtagaaga gtggtcagac caatatggct accatttctc tatctactca acaccatccg
    45121 aaagtctgac agaccgtttc tgccgactag atatagacaa gtttggctct attcctgata
    45181 tcacagacaa ggaatactac accaactctt tccactacga tgttcgtaaa aatccaacac
    45241 cgtttgaaaa attggacttt gagaaagtct atccagaagc aggtgcgtca ggtggtttca
    45301 tccattattg tgagtatcca gtccttcagc aaaatccaaa ggccttggaa gctgtctggg
    45361 attatgctta tgaccgtgta ggctatctag gcaccaatac tccgattgac cgttgctaca
    45421 agtgtgactt tgaaggggat tttgaaccaa ctgagagagg gtttgcttgt ccaaactgtg
    45481 gcaatagcga ccctaaaaca gtagatgtgg tgaagcgaac ttgtggctac ctaggtaatc
    45541 ctcaagcaag accgatggtc aacgggcgtc acaaggaaat cgctgcgcgt gtcaaacata
    45601 tgaatggttc aacgattaaa atagctgggc atcaagtaac aaattagaaa gaaatgaaat
    45661 gggaaaatat caactagacg ataaggggcg cgcacaagtg acccgttatc acgagaaaca
    45721 ctctaaaggt ggagctggta agaaagaacg cttgcttagc ttcagagaac aatttttaaa
    45781 caagaacaag aaaaaataaa agtgagagcc agctctcgct tttctcatag tgggaggtaa
    45841 ggatggaatt acgcagacca agattagcgg ataagaaagc tgttttagat atgatgacag
    45901 agtttgaaaa atttcagtcg cctcacgacg gcggtttatg ggatacagag aactttgtgt
    45961 atgaagactg gttagaaagc aatcaggaac aggaaatggg gattaatctg cctgaaggat
    46021 gggttcctgc aattcagtta gtggcttttt ctgagaaagg tcaagcagtt ggatttctta
    46081 atctccggtt gcgcctcagt aactttctac tagaagaagg tggccacatt ggctactcca
    46141 ttcgtccatc tgaaagaggc aagggttatg caaaagagac tctccgtcag ggcttgcaag
    46201 ttgctaagga aaagaacatc aagaaagctc tggtgacctg tagcgtgaat aatcctgcta
    46261 gcagagcagt cattctagca aatggtggaa tatttgagga tgctcgcaat ggagtcaagc
    46321 gttattggat agaggtagcg aatgaataat ccaaaaccac aagaatggaa aagcgaggaa
    46381 cttagtcaag gtcgtatcat tgactacaag gcctttaact ttgtggacgg cgaaggcgtg
    46441 cgtaactctc tctatgtatc aggctgtatg tttcactgcg agggatgtta taatgtagcg
    46501 acctggtcct tcaatgcagg cattccctat acagctgagt tggaagaaca gattatggca
    46561 gatcttgccc agccttatgt tcaggggtta accttactag gaggggagcc ttttcttaat
    46621 actgggattc tcttgccact tgttaagcgg attcggaagg aattgccaga caaggacatc
    46681 tggtcctgga cgggctacac ttgggaagaa atgatgttgg aaactccaga taaactggaa
    46741 ctcttgtcac tgattgacat tcttgtcgat ggaagatatg atcgaactaa gagaaatctt
    46801 atgctccagt ttcgaggttc gtccaaccaa cgaattatcg atgtgcaaaa atcgctcaaa
    46861 agtgggcaag tagtgatttg ggacaagctc aatgacggaa aagaaagcta tgaacaggtg
    46921 aagagagaat gaagaaaaaa gacttagtag accaactagt ctcagagatc gagacgggga
    46981 aagtcaggac actgggaata tacggtcatg gagcttcagg taaatcaacc tttgcacagg
    47041 aattgtacca agctttagat tctactacag taaatttgct agagacagat ccttatatca
    47101 cctcaggacg ccatctggta gtacccaagg acgcgccgaa tcaaaaggtg acagccagtc
    47161 tgccagtggc gcatgaactg gagagtttgc agagagatat ccttgccttg caggcgagta
    47221 tggatgtctt gacaattgaa gaaccttgga aggctagtga ggttttgtct ggagccaaac
    47281 caattttgat tgtcgaaggg atgtctgttg gctttctacc caaggaactc tttgaaaaaa
    47341 ccatctgttt ctacacggat gaggagaccg aattaaagcg acgccttgct agagatacga
    47401 ctgtgagaaa tcgcgatgca tcctttatat tggctagcca tcagatgaga cgggagcagt
    47461 atctgcgata ctataaagaa actgagtcta aggcggatat cttagtggac caatcagaag
    47521 ataaatttga tgtcaagagg acttaactta tgtatagaag aaatatagaa gaaaatccct
    47581 aattttagaa agaaaaagta ggaaaacagt ttcatcccaa aaaaacgaaa aaacagcaac
    47641 aaatcccttg caatcgcagg ggctttgtgt tattctatta tggtgctgta aattacagcc
    47701 ttagttttga tgcaagaggt tgcgacacgc tcggttgcat tgccacgcaa caccgcgtcg
    47761 gttttcttgt ggagctagcc tattatctta aatagacgaa aaggagaaaa agatggcaaa
    47821 caaaaaaatc cgtatccgtt tgaaagctta cgaacaccgt acgcttgaca cagcggctgc
    47881 aaaaatcgta gaatcagcta ctcgtacagg tgcacaagtt gcgggtccaa tcccacttcc
    47941 aactgaacgt agcctctaca caatcattcg tgcgactcac aaatacaaag attctcgcga
    48001 acaatttgaa atgcgtacac acaaacgttt gatcgatatc gttaacccaa ctcaaaaaac
    48061 agttgatgcc ttgatgaaat tggatcttcc aagtggtgta aacgtagaaa tcaaacttta
    48121 atctaaaata taaaagagca gaggctggtg tttcaatcta attgaacacg ggctaaactc
    48181 ggtgtgaaaa agataaactt cctagtgtct gctagacact gcgtcagttt cctattttga
    48241 cgttgagttt gacgtccttt gtatcttaga cttgagcata aaaaacgctc gttaaaaact
    48301 ttttgaataa aaatatagaa aaggaactat tttctcatga caaaaggaat cttagggaaa
    48361 aaagtgggaa tgactcaaat cttcactgaa gctggcgaat tgatccctgt aacagttatt
    48421 gaagcaactc caaacgttgt tcttcaagtt aaaactgttg aaacagacgg atacaacgct
    48481 atccaagttg gtttcgatga caaacgcgaa gtattgagca acaaacctgc taaaggacat
    48541 gtagcgaaag ctaacacggc tcctaagcgc ttcattcgtg aattcaaaaa cgttgaaggc
    48601 ttggaagttg gcgctgaaat cacagttgaa acattcgcag ctggagatgt tgttgacgta
    48661 acgggtactt ctaaaggtaa aggtttccaa ggtgttatca aacgccacgg acaatcacgt
    48721 ggaccaatgg ctcacggttc tcgttaccac cgtcgtccag gttctatggg gcctgttgca
    48781 cctaaccgcg tattcaaagg taaaaacctt gcaggacgta tgggtggcga ccgcgtaaca
    48841 attcaaaacc ttgaagttgt acaagttgtt ccagaaaaga acgttatcct tatcaaaggt
    48901 aacgtaccag gtgctaagaa atctcttatc actatcaaat cagcagttaa agctggtaaa
    48961 taataaagaa aggggaaatc agtcacaatg gcaaacgtaa cattatttga ccaaactggt
    49021 aaagaagctg gccaagttgt tcttagcgat gcagtatttg gtatcgaacc aaatgaatca
    49081 gttgtgtttg atgtaatcat cagccaacgc gcaagccttc gtcaaggaac acacgctgtt
    49141 aaaaaccgct ctgcagtatc aggtggtgga cgcaaaccat ggcgtcaaaa aggaactgga
    49201 cgtgctcgtc aaggttctat ccgctcacca caatggcgtg gtggtggtgt tgtcttcgga
    49261 ccaactccac gttcatacgg ctacaaactt ccacaaaaag ttcgtcgcct agctcttaaa
    49321 tcagtttact ctgaaaaagt tgctgaaaac aaattcgtag ctgtagacgc tctttcattt
    49381 acagctccaa aaactgctga atttgcaaaa gttcttgcag cattgagcat cgattctaaa
    49441 gttcttgtta tccttgaaga aggaaatgaa ttcgcagctc tttcagctcg taaccttcca
    49501 aacgtgaaag ttgcaactgc tacaactgca agtgttcttg acatcgcaaa tagcgacaaa
    49561 cttcttgtca cacaagcagc tatctctaaa atcgaggagg ttcttgcata atgaatttgt
    49621 atgatgttat caaaaaacct gtcatcactg aaagctcaat ggctcaactt gaagcaggaa
    49681 aatatgtatt tgaagttgac actcgtgcac acaaactttt gatcaagcaa gctgttgaag
    49741 ctgctttcga aggtgttaaa gttgccaatg ttaacacaat caacgtaaaa ccaaaagcta
    49801 aacgtgttgg acgttacact ggttttacta acaaaactaa aaaagctatc atcacactta
    49861 cagctgattc aaaagcaatc gagttgtttg ctgctgaagc tgaataatct aaggaggaaa
    49921 tatcgtggga attcgtgttt ataaaccaac aacaaacggt cgccgtaata tgacttcttt
    49981 ggatttcgct gaaatcacaa caagcactcc tgaaaaatca ttgcttgttg cattgaagag
    50041 caaggctggt cgtaacaaca acggtcgtat cacagttcgt caccaaggtg gtggacacaa
    50101 acgtttctac cgtttggttg acttcaaacg taataaagac aacgttgaag cagttgttaa
    50161 aacaatcgag tacgatccaa accgttctgc aaacatcgct cttgtacact acactgacgg
    50221 tgtgaaagca tacatcatcg ctccaaaagg tcttgaagta ggtcaacgta tcgtttcagg
    50281 tccagaagca gatatcaaag tcggaaacgc tcttccactt gctaacatcc cagttggtac
    50341 tttgattcac aacatcgagt tgaaaccagg tcgtggtggt gaattggtac gtgctgctgg
    50401 tgcatctgct caagtattgg gttctgaagg taaatatgtt cttgttcgtc ttcaatcagg
    50461 tgaagttcgt atgattcttg gaacttgccg tgctacagtt ggtgttgtcg gaaacgaaca
    50521 acatggactt gtaaaccttg gtaaagcagg acgtagccgt tggaaaggta tccgcccaac
    50581 agttcgtggt tctgtaatga accctaacga tcacccacac ggtggtggtg aaggtaaagc
    50641 accagttggt cgtaaagcac catctactcc atggggcaaa cctgctcttg gtcttaaaac
    50701 tcgtaacaag aaagcgaaat ctgacaaact tatcgttcgt cgtcgcaacg agaaataata
    50761 ttaaactagt cgcttaagca actagtaaat ccgccagctc ggtagcgctc cataggagtg
    50821 caagccgctg tggtacaaca tttaaaggag aaaatataaa aatgggacgc agtcttaaaa
    50881 aaggaccttt cgtcgatgag catttgatga aaaaagttga agctcaagct aacgacgaaa
    50941 agaaaaaagt tattaaaact tggtcacgtc gttcaacgat cttcccaagt ttcattggtt
    51001 acactattgc agtttatgac ggacgtaaac acgtacctgt ttacatccaa gaagacatgg
    51061 taggccacaa acttggtgaa tttgcaccaa ctcgtactta caaaggtcac gctgcagacg
    51121 acaagaaaac acgtagaaaa taaggagaac ataaatggca gaaattactt cagctaaagc
    51181 aatggctcgt acagtacgtg tttcacctcg taaatcacgt cttgttcttg ataacatccg
    51241 tggtaaaagc gtagccgatg caatcgcaat cttgacattc actccaaaca aagctgctga
    51301 aatcatcttg aaagttttga actcagctgt agctaacgct gaaaacaact ttggtttgga
    51361 taaagctaac ttggtagtat ctgaagcatt cgcaaacgaa ggaccaacta tgaaacgttt
    51421 ccgtccacgt gcgaaaggtt cagcttcacc aatcaacaaa cgtacagctc acatcactgt
    51481 agctgttgca gaaaaataag gaggtaaaat cgtgggtcaa aaagtacatc caattggtat
    51541 gcgtgtcggc atcatccgtg attgggatgc caaatggtat gctgaaaaag aatacgcgga
    51601 ttaccttcat gaagatcttg caatccgtaa attcgttcaa aaagaacttg ctgacgcagc
    51661 agtttcaact attgaaatcg aacgcgcagt aaacaaagtt aacgtttcac ttcacactgc
    51721 taaaccaggt atggttatcg gtaaaggtgg tgctaacgtt gatgcactcc gtgcaaaact
    51781 taacaaattg actggaaaac aagtacacat caacatcatc gaaatcaaac aacctgattt
    51841 ggatgctcac cttgtaggtg aaggaattgc tcgtcaattg gagcaacgtg ttgctttccg
    51901 tcgtgcacaa aaacaagcaa tccaacgtgc aatgcgtgct ggagctaaag gaatcaaaac
    51961 tcaagtatca ggtcgtttga acggtgcaga tatcgcccgt gctgaaggat actctgaagg
    52021 aactgttccg cttcacacac ttcgtgcaga tatcgattac gcttgggaag aagcagatac
    52081 tacatacggt aaacttggtg ttaaagtatg gatctaccgt ggtgaagttc ttccagctcg
    52141 taaaaacact aaaggaggta aataaccaat gttagtacct aaacgtgtta aacaccgtcg
    52201 tgagttccgt ggaaaaatgc gcggtgaagc aaaaggtgga aaagaagtag cattcggtga
    52261 atacggtctt caagctacaa ctagccactg gatcactaac cgccaaatcg aagctgctcg
    52321 tatcgccatg actcgttaca tgaaacgtgg tggtaaagtt tggattaaaa tcttcccaca
    52381 caaatcatac actgctaaag ctatcggtgt gcgtatggga tctggtaaag gggcacctga
    52441 aggttgggta gcaccagtta aacgtggtaa agtgatgttc gaaatcgctg gtgtatctga
    52501 agagattgca cgtgaagcgc ttcgacttgc tagccacaaa ttgccagtta aatgtaaatt
    52561 cgtaaaacgt gaagcagaat aaggagaagg catgaaactt aatgaagtaa aagaatttgt
    52621 taaagaactt cgtggtcttt ctcaagaaga actcgcgaag cgcgaaaacg aattgaaaaa
    52681 agaattgttt gaacttcgtt tccaagctgc tactggtcaa ttggaacaaa cagctcgctt
    52741 gaaagaagtt aaaaaacaaa tcgctcgtat caaaacagtt caatctgaag cgaaataata
    52801 gactagggaa ggagaaattt caatggaacg caataatcgt aaagttcttg ttggacgtgt
    52861 tgtatctgac aaaatggaca agacaatcac agttgtagtt gaaacaaaac gtaaccaccc
    52921 agtctatggt aaacgtatta actactctaa aaaatacaaa gctcatgatg aaaacaatgt
    52981 tgccaaagaa ggcgatatcg tacgtatcat ggaaactcgc ccgctttcag ctacaaaacg
    53041 tttccgtctt gtagaagttg ttgaagaagc ggtcatcatc taatcaaacc tgaaaggaga
    53101 aaactgaaat gattcaaaca gaaactcgtt tgaaagtcgc agacaacagc ggtgctcgcg
    53161 aaatcttgac tatcaaagtt cttggtggtt caggacgtaa atttgcaaac atcggtgatg
    53221 ttatcgtggc atctgtaaaa caagctactc ctggtggtgc ggttaaaaaa ggtgacgttg
    53281 ttaaagcagt tatcgttcgt actaaatcag gtgctcgtcg tgctgatggt tcatacatca
    53341 aatttgacga aaacgcagca gttatcatcc gtgaagacaa aactcctcgc ggaacacgta
    53401 tctttggccc agttgcacgt gaattgcgtg aaggtggttt catgaagatc gtgtcacttg
    53461 ctccagaagt actttaattt ttaggaacaa actagtcccc tagcttcaag ctagggtgcc
    53521 cttatgggcg taagaaaaat caaggagaaa cctaatgttt gtaaaaaaag gcgacaaagt
    53581 tcgcgtaatc gctggtaaag ataagggaac agaagctgtt gtccttactg cccttccaaa
    53641 agtaaacaaa gttatcgttg aaggtgttaa cattgttaag aaacaccaac gtccaactaa
    53701 cgagcttcct caaggtggta tcatcgagaa agaagcagct atccacgtat caaatgttca
    53761 agttttggac aaaaatggtg tagctggtcg tgttggttac aaatttgtag acggtaaaaa
    53821 agttcgctac aacaaaaaat caggcgaagt gcttgattaa tcacgaagga aaggagaagt
    53881 ataatggcaa atcgtttaaa agaaaaatat cttaatgaag tagttcctgc tttgacagaa
    53941 caattcaact actcatcagt gatggctgtg cctaaagtag ataagattgt tttgaacatg
    54001 ggtgttggtg aagctgtatc aaacgctaaa agccttgaaa aagctgctga agaattggca
    54061 cttatctcag gtcaaaaacc acttatcact aaagctaaaa aatcaatcgc cggcttccgt
    54121 cttcgtgaag gtgttgcgat cggtgcaaaa gttacccttc gtggtgaacg tatgtacgaa
    54181 ttcttggata aattggtatc agtttcactt ccacgtgtac gtgacttcca cggtgtccca
    54241 acaaaatcat ttgatggacg cgggaactac acacttggtg tgaaagaaca attaatcttc
    54301 ccagaaatca acttcgatga cgttgacaaa actcgtggtc ttgacatcgt tatcgtaaca
    54361 actgctaaca ctgacgaaga gtcacgtgca ttgcttacag gccttggaat gccttttgca
    54421 aaataatata ggaggtaaat ctaatggcta aaaaatcaat ggtagctaga gaggctaaac
    54481 gccaaaaaat tgttgaccgt tatgctgaaa aacgtgctgc attaaaggcg gcaggggact
    54541 acgaaggttt atctaaatta cctcgcaacg cctcaccgac tcgtttacat aatcgttgta
    54601 gggttacggg gcgcccacat tcagtttacc gcaaatttgg tctgagtcgt atcgcttttc
    54661 gcgaacttgc gcataaaggt caaattcctg gtgtaacaaa agcatcttgg taatttaaga
    54721 tatcaagagc gtcaaaactc caagtaaaaa taggaaactt gacgaagaaa ctaaagtttc
    54781 taggaaagtt tatctttttc acacagagtt tagcccgtgt tcaattgggc ttgccaattt
    54841 gaacacgagc tacagctttg gcaaaaaaga ccaatttgct ttggagcatt gcttctgcat
    54901 taaattgtct atttttgctc gtgctgttac gctctttgta tcatgtatta actagcaagt
    54961 gcaacttgca aactactagt aagaggagaa aaacaaaatg gttatgactg acccaatcgc
    55021 agacttccta actcgtattc gtaatgctaa ccaagctaaa cacgaagtac ttgaagtacc
    55081 tgcatcaaac atcaaaaaag ggattgctga aatccttaaa cgcgaaggtt ttgtaaaaaa
    55141 cgttgaaatc attgaagatg acaaacaagg cgtcatccgt gtatttctta aatacggacc
    55201 aaatggtgag aaagttatca ctaacttgaa acgtgtttct aaaccaggac ttcgtgtcta
    55261 caaaaaacgt gaagaccttc caaaagttct taacggactt ggaattgcca tcctttcaac
    55321 ttctgaaggt ttgcttactg ataaagaagc acgccaaaag aatgttggtg gtgaggttat
    55381 cgcttacgtt tggtaaaatc aagatacaaa gctcgtaaag aacaaagcaa aattaggaag
    55441 ttggagaagt ttgtttacaa acaagccaac ttatctattt tgcacagttc ttagagcgtg
    55501 ttcagttcag ctcttgaact aaataagtat ctgaaccccg tgaaaactgg ccgttctggc
    55561 ctgacaatct aacaggagaa aataaacatg tcacgtattg gtaataaagt tatcgtgttg
    55621 cctgctggtg ttgaactcgc taacaatgac aacgttgtaa ctgtaaaagg acctaaagga
    55681 gaacttactc gtgagttctc aaaagatatt gaaatccgtg tggaaggtac tgaaataact
    55741 cttcaccgtc caaacgattc aaaagaaatg aaaactatcc acggaactac tcgtgccctt
    55801 ttgaacaaca tggttgttgg tgtatcagaa ggattcaaga aagaacttga aatgcgtggg
    55861 gttggttacc gtgcacagct tcaaggatct aaacttgttt tggctgttgg taaatctcat
    55921 ccagacgaag ttgaagctcc agaaggaatt acttttgaac ttccaaaccc aacaacaatc
    55981 gttgttagcg gaatttcaaa agaagtagtt ggtcaaacag ctgcttacgt acgtagcctt
    56041 cgttcaccag aaccatataa aggtaaaggt atccgttacg ttggtgaatt cgttcgccgt
    56101 aaagaaggta aaacaggtaa ataatgttga gtggttgatc atcaaccacc aacctatttt
    56161 ccaactttgt gcatagcaca cgatttaaaa ctaaagaggt gaaaactgtg atttcaaaac
    56221 cagataaaaa caaactccgc caaaaacgcc accgtcgcgt tcgcggaaaa ctctctggaa
    56281 ctgctgatcg cccacgtttg aacgtattcc gttctaatac aggcatctac gctcaagtga
    56341 ttgatgacgt agcgggtgta acgctcgcaa gtgcttcaac tcttgataaa gaagtttcaa
    56401 aaggaactaa aactgaacaa gccgttgctg tcggtaaact cgttgcagaa cgtgcaaacg
    56461 ctaaaggtat ttcagaagtg gtgttcgacc gcggtggata tctatatcac ggacgtgtga
    56521 aagctttggc tgatgcagct cgtgaaaacg gattgaaatt ctaataggag gacactagaa
    56581 aatggcattt aaagacaatg cagttgaatt agaagaacgc gtagttgctg tcaaccgtgt
    56641 tacaaaagtt gttaaaggtg gacgtcgtct tcgtttcgca gctcttgttg ttgttggtga
    56701 ccacaatggt cgcgtaggat ttggtactgg taaagctcaa gaagttccag aagcaatccg
    56761 taaagcagta gatgatgcta agaaaaactt gatcgaagtt cctatggttg gaacaacaat
    56821 cccacacgaa gttctttcag aattcggtgg agctaaagta ttgttgaaac ctgctgtaga
    56881 aggttctgga gttgccgctg gtggtgcagt tcgtgccgtt gtggaattgg caggtgtggc
    56941 agatattaca tctaaatcac ttggttctaa cactccaatc aacattgttc gtgcaactgt
    57001 tgaaggtttg aaacaattga aacgcgctga agaaattgct gcccttcgtg gtatttcagt
    57061 ttctgatttg gcataagaaa ggggataaaa tggctcaaat taaaattact ttgactaagt
    57121 ctccaatcgg acgcattcca tcacaacgta aaactgttgt agcacttgga cttggcaaat
    57181 tgaacagctc tgttattaaa gaagataacg ctgctatccg tggtatgatc acagcagtat
    57241 ctcacttagt aacagttgaa gaagtaaact aatgaagttt taggggatgt gcactgtacc
    57301 atcccctaaa actagatata gtcatctatg atgacatcgt ataggcgagt tgatggggga
    57361 gacaaccttt tctcccttat cggcgctagc attttacaaa agaggagaaa ataaaaatga
    57421 aacttcatga attgaaacct gcagaaggtt ctcgtaaagt acgtaaccgc gttggtcgtg
    57481 gtacttcatc aggtaacggt aaaacatctg gtcgtggtca aaaaggtcaa aaagctcgta
    57541 gcggtggcgg agttcgcctt ggttttgaag gtggacaaac tccattgttc cgtcgtcttc
    57601 caaaacgtgg attcactaac atcaacgcta aagaatacgc aattgtgaac cttgaccaat
    57661 tgaacgtctt tgaagatggt gctgaagtaa ctccagttgt tcttatcgaa gcaggaattg
    57721 ttaaagctga aaagtcaggt attaaaattc ttggtaacgg tgagttgact aagaaattga
    57781 ctgtgaaagc agctaaattc tctaaatcag ctgaagaagc tatcactgct aaaggtggtt
    57841 cagtagaagt catctaagag aggtgaccta tgttttttaa attattaaga gaagctctta
    57901 aagtcaagca ggttcgatca aaaattttat ttacaatttt tatcgttttg gtctttcgta
    57961 tcggaactag cattacagtt cctggtgtga atgccaatag cttgaatgct ttaagtggat
    58021 tatccttctt aaacatgttg agcttggtgt cggggaatgc cctaaaaaac ttttcgattt
    58081 ttgccctagg agttagtccc tatatcaccg cttctattgt tgtccaactc ttgcaaatgg
    58141 atattttacc caagtttgta gagtggggta aacaagggga agtaggtcga agaaaattga
    58201 atcaagctac tcgttatatt gctctagttc tcgcttttgt gcaatctatc gggattacag
    58261 ctggttttaa taccttggct ggagctcaat tgattaaaac tgctttaact ccacaagttt
    58321 ttctgacgat tggtatcatc ttaacagctg gtagtatgat tgtcacttgg ttgggtgagc
    58381 aaattacaga taagggatac ggaaacggtg tttccatgat tatctttgcc gggattgttt
    58441 cctcaattcc agagatgatt cagggcatct atgtggacta ctttgtgaac gtcccaagta
    58501 gccgtatcac ttcatctatc attttcgtaa tcattttgat tattactgta ttgttgatta
    58561 tttactttac aacttatgtt caacaagcag aatacaaaat tccaatccaa tatactaagg
    58621 ttgcacaagg tgctccatct agctcttacc ttccgttaaa ggtaaatcct gctggagtta
    58681 tccctgttat ctttgccagt tcgattactg cagcgcctgc ggctattctt cagtttttga
    58741 gtgccacagg tcatgattgg gcttgggtaa gggtagcaca agagatgttg gcaactactt
    58801 ctccaactgg tattgccatg tatgctttgt tgattattct ctttacattc ttctatacgt
    58861 ttgtacagat taatcctgaa aaagcagcag agagcctaca aaagagtggt gcctatatcc
    58921 atggagttcg tcctggtaaa ggtacagaag aatatatgtc taaacttctt cgtcgtcttg
    58981 caactgttgg ttccctcttc cttggtgtga tttccatttt accgattgca gctaaagatg
    59041 tatttggtct ttctgatgtt gttgcctttg gtggaacaag tctcttgatc attatctcta
    59101 caggtatcga aggaatcaag caattggaag gttacctatt gaaacgtaag tatgttggtt
    59161 tcatggacag aacagaataa aagtatttac tgaatcagta aatgctgagg gagtggaggt
    59221 ttaaactctg acatttgtaa gagttggatc tcccctcttc tattttgttt ttaaataggg
    59281 gtgaaaagac tttttgcttc tatttaaaaa taaaataagg agatcaaatc atgaatcttt
    59341 tgattatggg cttacctggt gcaggtaagg gaactcaagc agcaaaaatc gtagaacaat
    59401 tccatgttgc acatatctca acaggtgata tgttccgcgc tgcaatggca aatcaaactg
    59461 aaatgggtgt tcttgctaag tcatatattg acaagggtga attggttcct gacgaagtta
    59521 caaatggaat cgtaaaagaa cgtctttcac aagatgatat taaagaaaca ggattcttat
    59581 tggatggtta cccacgtaca attgaacaag ctcatgcctt ggacaaaaca ttggctgaac
    59641 ttggcattga actagaaggt gttatcaata ttgaagtgaa ccctgacagc ctcttggaac
    59701 gtttgagtgg ccgtatcatc caccgcgtaa ctggagaaac tttccacaag gtctttaacc
    59761 caccagttga ctataaagaa gaagattatt accaacgtga agatgataag cctgagacag
    59821 taaaacgtcg tttggatgtt aatattgctc aaggagaacc aatcattgct cactaccgtg
    59881 ccaaaggttt ggttcatgac atcgaaggta atcaagatat caatgatgtc ttctcagata
    59941 ttgaaaaagt attgacaaat ttgaaataaa gcgtttttca tacttgcaaa aattcgctac
    60001 aaatgttata ctgaaatagt ctgacttata attgttgtct ctgtgtctag aggcatcgaa
    60061 tcgaaattta tggaggtgct tttgcgtggc aaaagacgat gtgattgaag ttgaaggcaa
    60121 agtagttgat acaatgccga atgcaatgtt tacggttgaa cttgaaaatg gacatcagat
    60181 tttagcaaca gtttctggta aaattcgtaa aaactatatt cgtattttag cgggagatcg
    60241 tgttactgtc gaaatgagtc catatgactt gacacgtgga cgtatcactt accgctttaa
    60301 ataatcgaaa aacttggagg gataagaaat gaaagtaaga ccatcggtca aaccaatttg
    60361 cgaatactgt aaagttattc gtcgtaatgg tcgtgttatg gtaatttgcc cagcaaatcc
    60421 aaaacacaaa caacgtcaag gataagatag aaaggagaaa acatggctcg tattgctgga
    60481 gttgatattc caaatgacaa acgcgtagta atctcattga cttatgttta tggtatcgga
    60541 cttgcaacat ctaagaaaat tttggctgct gctggaatct cagaagatgt tcgtgtacgt
    60601 gatcttacat cagatcaaga agatgctatc cgtcgtgaag tggatgcaat caaagttgaa
    60661 ggtgaccttc gtcgtgaagt aaacttgaac atcaaacgtt tgatggaaat cggttcatac
    60721 cgtggtatcc gtcaccgtcg tggacttcct gtccgtggac aaaatactaa aaacaacgct
    60781 cgcactcgta aaggtaaagc tgttgcgatt gctggtaaga aaaaataata taggaggtaa
    60841 aagtcttggc taaaccaaca cgtaaacgtc gtgtgaaaaa gaatatcgaa tctggtattg
    60901 ctcatattca cgctacattt aataacacta ttgttatgat tactgatgtg catggtaatg
    60961 caattgcttg gtcatcagct ggtgctcttg gtttcaaagg ttctcgtaaa tctacaccat
    61021 tcgctgctca aatggcttct gaagctgctg ctaaatctgc acaagaacac ggtcttaaat
    61081 cagttgaagt tactgtaaaa ggtccaggtt ctggtcgtga gtcagctatt cgtgcgcttg
    61141 ctgccgctgg tcttgaagta acagcaattc gtgatgtgac tccagtgcca cacaatggtg
    61201 ctcgtcctcc aaaacgtcgc cgtgtataat catcgcatta cactgctttt cgtttaagag
    61261 ggagtaacta aatgatcgag tttgaaaaac caaatataac aaaaattgat gaaaataaag
    61321 attatggcaa gtttgtaatc gaaccacttg aacgtggcta cggtacaact cttggtaact
    61381 ctcttcgtcg tgtacttcta gcttctctac caggagcagc tgtgacatct atcaacattg
    61441 atggtgtgtt acatgagttt gacacagttc caggtgttcg tgaagacgtg atgcaaatca
    61501 ttctgaacat taaaggaatt gcagtgaaat cgtacgttga agacgaaaaa atcatcgaac
    61561 tggatgttga aggtcctgct gaagtaacag ctggtgacat tttgacagat agcgatattg
    61621 aaattgtaaa tccagatcat tatctcttta caattggtga aggttcttct ctaaaagcga
    61681 ctatgactgt taacagtggt cgtggatatg tacctgctga tgaaaataaa aaggataatg
    61741 caccagttgg aacacttgct gtagattcta tttatacacc agttacaaaa gtcaactatc
    61801 aagtggaacc tgctcgtgta ggtagcaatg atggtttcga caaattaacc cttgaaatct
    61861 tgacaaatgg aacaattatt ccagaagatg ctttagggct ttcagcacgt attttgacag
    61921 aacatcttga tttgtttaca aatcttactg agattgctaa gtcaactgaa gtgatgaaag
    61981 aagctgatac tgaatctgac gaccgtattt tagatcgtac gattgaggaa ctggacttgt
    62041 ctgtgcgttc atacaactgt ttaaaacgtg ccggtatcaa tactgtgcat gatttgacag
    62101 aaaaatctga agcagagatg atgaaagtac gaaatcttgg acgcaagagt ttggaagaag
    62161 tgaaactcaa actcattgat ttgggtcttg gattaaaaga taaataaagg aggaatacat
    62221 ggcttaccgt aaactaggac gcactagctc acaacgtaaa gcaatgcttc gcgatttgac
    62281 aactgacctt ttgatcaacg aatcaatcgt gacaactgaa gctcgtgcta aagaaatccg
    62341 taaaactgtt gaaaaaatga ttactctagg taaacgtggt gatttgcatg cacgtcgtca
    62401 agcagctgct ttcgtacgta atgaaatcgc atctgaaaac tatgatgaag caactgataa
    62461 gtacacttct actacagcac ttcaaaaatt gttctcagaa atcgcacctc gttatgctga
    62521 acgtaacggt ggatacactc gtatccttaa aactgaacca cgtcgtggtg atgcagcgcc
    62581 aatggcgatc atcgaattag tataaaatca tcaattttgt tgagtgttat gatgatggag
    62641 tcttgtgctc ttagtctagc tctggtctac cgctaggatt tcggtcctag cgggaacact
    62701 catcataagt tgggatagta gacgcttgtt tacgaaattg tttttttctt aagaacaact
    62761 tcgtaagcag gcgtttttga gtattttcgt tagaattatg ctatactatt tgaaaagaat
    62821 cctgtttaat gttaaggttt cttattttaa gaagaattgg agtttactta tgaaagccat
    62881 tataactgtt gttggtaaag ataaatctgg aattgttgca ggtgtttctg gtaaaattgc
    62941 agaattagga ttgaatattg acgatatctc tcaaactgtc ttggatgaat attttacgat
    63001 gatggctgtt gtatctagtg atgaaaagca agattttacc tatcttcgta atgaatttga
    63061 agcttttggg caaactttga atgtaaaaat caatattcag agtgcagcga ttttcgaagc
    63121 tatgtataat atctaggagg tcatcatgga tattagacaa gttactgaaa ccatcgccat
    63181 gattgaggag caaaacttcg atattagaac cattaccatg gggatttctc ttttggactg
    63241 tatcgatcca gatatcaatc gtgctgcgga gaaaatctat caaaaaatta cgacaaaggc
    63301 ggctaattta gtagctgttg gtgatgaaat tgcggctgag ttgggaattc ctatcgttaa
    63361 taagcgtgta tcggtgacac ctatttctct gattggggca gcgacagatg cgacggacta
    63421 cgtggttctg gcaaaagcgc ttgataaggc tgcgaaagag attggtgtgg actttattgg
    63481 tggtttttct gccttagtac aaaaaggtta tcaaaaggga gatgagattc tcatcaattc
    63541 cattcctcgc gctttgactg agacggataa ggtctgctcg tcagtcaata tcggctcaac
    63601 caagtctggt attaatatga cggctgtggc agatatggga cgaattatca aggaaacggc
    63661 aaatctttca gatatgggag cggctaagtt ggttgtattc gctaatgctg ttgaggacaa
    63721 tccatttatg gcgggtgcct ttcatggtgt tggggaagca gatgttatca tcaatgtcgg
    63781 agtttctggt cctggtgtgg tgaaacgtgc tttggaaaaa gttcgtggac agagctttga
    63841 tgtagtagcc gaaacagtta agaaaactgc ctttaaaatc actcgtatcg gtcaattggt
    63901 tggtcaaatg gccagtgaga gactgggtgt ggagtttggt attgtggact tgagtttggc
    63961 accaacccct gcgattggag actctgtggc acgtgtcctt gaggaaatgg ggctagaaac
    64021 agttggcacg catggaacga cggttgcctt ggccctcttg aacgaccaag ttaaaaaggg
    64081 tggagtgatg gcctgcaacc aagtcggtgg tttatctggc gcctttatcc ctgtttctga
    64141 ggatgaagga atgattgctg cagtgcaaaa tggctctctt aatttagaaa aactagaagc
    64201 tatgacggct atctgttctg ttggattgga tatgattgcc atcccagaag atacgcctgc
    64261 tgaaaccatt gcggctatga ttgcggatga agcagcaatc ggtgttatca acatgaaaac
    64321 aacagctgtt cgtatcattc ccaaaggaag agaaggcgat atgattgagt ttggtggtct
    64381 attaggaact gcacctgtta tgaaggttaa tggggcttcg tctgtcgact tcatctctcg
    64441 cggtggacaa atcccagcac caattcatag ttttaaaaat taagaaaata ggagaaattt
    64501 taagttctat ttaagattag atgtgtatac tataatcatt aaataaagac ctcctaatat
    64561 tatttgaaac agataacact gaattagttt gaatttgatt ttcatctaat atctttattt
    64621 aatgaactcc taaacttttt cataataatc tccttcaaaa gtcgcctgta tgggtggctt
    64681 ttattttatc attcatgata taatagaagc aaacggagga cggaaaatgg taaaagtacg
    64741 attgtatttg gtacgtcatg gcaagaccat gtttaacacg attggtcgcg cgcaaggttg
    64801 gagcgatact cccttaactg ctgaaggtga acgagggatt caagagttag gaatcggttt
    64861 gcgagaatct gatctacagt ttgagcgcgc ttattcgagt gattctggtc gtaccattca
    64921 gaccatggga attatccttg aagaacttgg cttgcagggg aaaatccctt atcgcatgga
    64981 caagcgtatc agagaatggt gtttcggtag ttttgatgga gcctatgatg gcgatctttt
    65041 catgggcatt attcctcgta tctttaatgt ggaccacgtt caccaattgt cttatgctga
    65101 actggctgag ggcttggtag aggtcgatac agctggttgg gctgaaggct gggaaaaact
    65161 cagtggccga atcaaggaag gctttgaaat gattgcaaaa gaaatggaag atcaaggtgg
    65221 aggtaacgcc cttgttgtca gccatggaat gactattgga accattgttt atctgattaa
    65281 tggcatgcat ccgcatggtc tagataatgg tagcgtgacg attcttgaat atgaggacgg
    65341 tcagtttagg gttgaagttg tcggtgaccg tagttaccga gagctaggat gtgagaagat
    65401 ggaagaaggc tctatttaat cagtctagac ttgcttgcca tgagctaggg atttgataag
    65461 aatatcaaga taagaaaaaa cagccgaggg cactcctttc ggctgttttt gatgtggaaa
    65521 actaaagtgt aatgctattg cttttagaga ttttcataaa caagagcaag gaacctactg
    65581 ttagaacagt caggatagtt gacaaggctg cggctacacc gtaatttcct ctgagaacct
    65641 ctgtataaat agctacagtc attgttcttg ttttgacatt gtagaggagg atagaagtag
    65701 agagttttga aatcattgtg acccaagata agatggctcc agaaatgata ccagatagca
    65761 tcattggagt tgtaatctta gcaaaggtat tgagacgact acttcctaag ctttcagcag
    65821 cttcttcaat acttggtgct atttgttgta agctagcaac agatgagcga atagtataag
    65881 gtaatcttct gacagataga gacataatca agatgaaagc agtccctgta atcataagaa
    65941 atccacttcc aaatagacca gtattgaagg aagaaatgaa ggcaatccct agaacggttc
    66001 ctggtacaat ataaggtacc atactgaggc tgtcaattaa gtttgtaaac aaattccgtt
    66061 ttctaacggc taggtaggag ataaatgtcg caaatagaac aactagaact aaggcaatca
    66121 aagggatacg aatggtattg aaaatagcag atcccatacg attgaaagct accttgtaac
    66181 tgtttggaga ataaccttta acagatacca tacctgatgt ttttaggaaa gaggtataaa
    66241 ttaagtagat ttgaggtaaa acagagataa agataattcc gtagactgtt gcataaatgg
    66301 cagctatttt tccttttgta gtttttttag gctcaattgg atggagcaga ttcatgctga
    66361 aactgtagcg gtttgcaatg tgtttttgga taaggaaaat tgccaaggca atgataatcg
    66421 ccataattgc aaaagcagaa tttcctccaa cctcgctaat aaattgggta taaatcagga
    66481 cagggaaagt ccgatatcct tcgtcaatca acataggcgt tccaaagtct gagaatgctc
    66541 tcataaatac aagcaaggag ctgctagtaa ggttggaact aggagaggta aaacaaccgt
    66601 tacgatacgc ttaaatccga aggaccccat gctttcagct gcttcaagta gagaattgtc
    66661 aatactgttc attgttccag caacatatag aaataccagt gggaatagtt gcagtgtaaa
    66721 gacaagtaca attcctttga atccataaat atcgatagct ggaagatgaa gggcatttgt
    66781 caaaaattta gtgatgacct catttcgtcc cagcaagaga attcaggagt aggctcctac
    66841 gaaaggagct gacatggaag caatgataat caatatttgt agaaatttct tccccttgaa
    66901 gtcatacata gagaagagat aagctaatag ggttcctaca actaaggaag tgatagtagc
    66961 ggtaatggaa accttgaaac tgttgactag tgtctcagag tagtaggctt tactaaagaa
    67021 agtgacaaaa ttagctagtg agaattgtcc ttcatgtata agtgcttgct tgagcacggt
    67081 aacgatagga taaacgagaa agacaagata ggtaagaaag atgaagaaag aggaagctgt
    67141 ccaaatattt agttttttac attccatggt tgactccttt tatcaggttt tgggaaccat
    67201 ctgcagaaaa gatgtttaat ttttgcgtat tgattcgtag acgaatacga ttgccttttt
    67261 gtagttcttc ttcaaaagtt gattcttcac taacttaaat ttttgaggca aaacctgtct
    67321 caatgaaata ctccgtattt agtccaagat agacgctatc gctaatagtt ccttcgatat
    67381 ctccagattc atctttgata aactcttcgg gacgaatgct tacatgaata gcttgctcct
    67441 caacctgatc aagagctggc attcgaaggg catagccatc tgaaaagacg atataagcgc
    67501 cgtcgctccg tttttcaaga ttggcaggga taatatttgt gcgtccgata aaggttgcca
    67561 caaactcatt agctggttta tgatagagtt attttggtcg gccgatttgt tggatcaccc
    67621 catctttcat aacagcaatt tggtctgaaa tagccatggc ttcttcttgg tcgtgggtta
    67681 cataaacagt tgtaattccc acttcgtgtt ggatttctcg gatggcttga cgcatatcca
    67741 agcgaagttt ggcctccaga ttactaagtg gctcgtccat gaggagaaca cttggattaa
    67801 ccgctaaggc gcatgccaag gtgacacgtt gttgttgtcc accactgagt ttatcgggct
    67861 ttcgatccgc atattgagca atttgcatga gttcaagata cttgttggtc tgttgaatca
    67921 attcttcttt tggaaccttc ttttgcataa gaccaaaagc aacgttgtct cggacagtca
    67981 aatgtgggaa aatagcgtag ttttggaaaa ccatcccgat attgcgtttg ctgggttcca
    68041 tattattgat ttttgtatca tcgaagtaaa attctccacc ttcgatactg ttgaaacctg
    68101 caatcatacg aagaagggtc gttttcccac atcctgaagc tccaagaagg gtaaagagac
    68161 ttccttttgg aattgtaatg ttcaaattct caataacagg gacatcgtgg tagatttttt
    68221 tggcgttaat aatttcgatc tcactcatag tgaacctctt ttactgttta gattggatat
    68281 ctgtaaagac ttcgttgtat ttcttaacga tatctgattt attcttgatg acataatcat
    68341 aatcttcagt gagtgttttg attttgtcaa ttggtttcat gttttcgctt gttttagcat
    68401 ttttacgaac aggacggtta gtagtggttg taccaagtgt atcttgtact tcttgagaga
    68461 taataaaatc gataaatttc ttggcatttt ccatattttt agatttttta acgatagcag
    68521 cactagcagg taggaagacg gttccttctt ttggatagac taccttaatg ttagctccgt
    68581 catttaagag tttaactgct ggatcttcat aagagagact aacagtcatt tctccatcag
    68641 cgactgcttt atagacacca gatgaactta aaccgatttt atagtatatt gaaactagaa
    68701 tagtacacat ctacttctaa aacattgtta gaaatcgatt tgactgtcct gattaatttg
    68761 tcctgttctt atttcatttt actataccat caataagtgt gaaaagatct tttacataag
    68821 accaagcctt atcatctttg taaccacctt gagcttgtag catatttgtt aattgagcaa
    68881 aggcgctaga agagtttgct gggtcagcag ttgcgatttt tccttttagt tcaggtttga
    68941 gaaggtcgct atatccttcg atgttcatgc ctttagttaa atcagggtgg acgattaaaa
    69001 cactaccatc tagtgtataa ggagtagaga agccagttgt gttttgatat tctttgataa
    69061 cattatcatt ttcttttgaa atatagtttt caaagagttc tccgtgggta gcatattgtg
    69121 tataagaacc accaaagata atatcagcta caggaacttc tttttctgac tctagttttt
    69181 tgaaaagttc tccagtacca gcttgaatca gttctatttt gataccatat ttttcttcaa
    69241 aggcaggaat agttgctcca attaagcctt ctgagtttgg tgaataaacg actagcgaac
    69301 caccgtctcc tttatcagat gaactgtcat cggcagattc attagaagaa caagcagcat
    69361 aatacatcca tttctttttc atgatggata cctccgttgt gttatttaag tttattttaa
    69421 aacaatgtaa gcgtttttaa aacctacaat tctattctat agtgtattga atctataaca
    69481 gtacacattg actgctaaaa tatttctata aattaatttg actttcctga tagagatgtt
    69541 cacatcttat ttcaattcac tatattagag taaaattctc tacaaaaaaa agaatagcct
    69601 attttactat ttttccgagt gatttcaatt cctttgggga aatatggaga tactttttaa
    69661 atcctgacaa atggttgttt ctttttctaa atcggtgata ctgtatcgga gaatgcgcgt
    69721 gaggtcacaa aggctgcgat agagcttcta tggagaattt ctttttggag agatttttta
    69781 aaggaatgag acatccgcta cctccttgga aggttttttt gtgataagta tagcagttta
    69841 aaaattctag agcaaggtaa aatagaaaag gtttggctaa aattttttag ctaaaccttt
    69901 tgaaaagtta agtatgtatt atagatgctt gttatctgca aatagctaga gcatttcaag
    69961 gaaataaact agaaataaca attaatatgg tggttcagaa ataccttttg ataatcaata
    70021 agatcttcag gatgaagtgc gttgattcca tccatttcat atttccgatt taataaacga
    70081 tatttgtttt caccaaattg atgaaaaggg agtagttgaa cttggtcgat atttaatgag
    70141 ttaaatagag tagcgaattt ttctgcatcc tctaaactat tgttaaaatt aggaataact
    70201 gggattctta aaacgatagt tttattttgt gaaaaagcat aatgaatgtt tttaataatc
    70261 atttgattaa aaaccccagt cactttttta tgttttatag aattataatg ttttaggtct
    70321 gtgtagataa aatccacata ttgaattaaa tcaataaatt tttcatgatc aacaaaggca
    70381 gtagtttcaa tggcagtgtg tatgtgatgt tctttagctg attttaagat agctttagca
    70441 aattcaaact gagcaaatat ttcacctcct gataaagtta aacctccacc ggattcttcg
    70501 taaaattctt tgtcttttaa tacctctgta ataatttctt ctacagtctt ttcttcaccg
    70561 actaaggtga atttctctcg ttgagcatct ttcatttttt caggtttcat tctttgagat
    70621 tcaggattag aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac agttgtacga
    70681 atacccgggc cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc tttagatatt
    70741 tccataagag ttcctcctct tcataagtct atcctatcac aaaaacgaaa gaaaaacaat
    70801 tacgaacgaa aggttaattt gttgtttttt gctttttatt ttggtagaat aaaacggagg
    70861 tgtaaaatga aaagattgga acaaattatt aaattagtat cagaatatga aaagatcgac
    70921 gttaatacat tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa agatttagat
    70981 aaattagagt caaaaggttt attacacaga gagcatggat atgctgtatt aaatagtgga
    71041 gatgacttaa atgtacgttt gtcaattaat tatgaaatta agagaaaaat tgttcaggaa
    71101 gcagtaaaat tggtgtcaga taatgaaacg ataatgatag aatctggatc gacctgtgct
    71161 ttacttgctg aggaaatttg caagcaaaaa agaaatgtta cgattgtaac aaattcattt
    71221 tttatagcaa attttgtgag agcttatgat tcatgtcgta ttattgttct tggtggagag
    71281 tttcagaagg attcacaggt tactgtggga cctttattaa aagaaatgat acagactttt
    71341 catgtgcatc aagcttttgt tgggacagat ggatacgata aagagatggg ctttacagga
    71401 aaagatttaa tgcgcagtga ggtagttcaa tatatttcag cagcgtcgga taaagtcatt
    71461 gtcctaactg actcaagtaa atttgataaa aggggtacag taagaagatt tgctttaagt
    71521 caagtctatg aagtaataac agacgaaaaa ctttctaaac aaaatatagc tacattagaa
    71581 aatgctggga taatggttaa ggtagtttcg taagaggtta agtgtatgaa tcaagatagg
    71641 aataaactgc tctctaaaat tgcttatctg tattatattg aaaacttaaa tcagtcacaa
    71701 atagcagcaa aattaggaat ttatagaacc tctattagta gaatgttaac agaagcaagg
    71761 aatgcaggaa ttgttaaaat tgaaatagag aattttgata ccaatatgtt taagttggaa
    71821 aattatgtaa aagaaaaata tggtctggaa agtttagaaa ttattccaaa tgaatttgat
    71881 gataatccaa caattttatc tgaaagaatt tctcaagttg cagcaggtgt ccttaggaat
    71941 ctaattgatg ataatatgaa aattggcttt tcttggggga aaagtttaag taatttagta
    72001 gatttaattc acagtaaaag tgtccgaaat gttcacttct atcctctagc aggtggtcct
    72061 agtcacatac acgctaaata ccatgtgaat acactgattt atgaaatgtc tagaaaattt
    72121 catggagagt gtacatttat gaatgcaacg attgtgcaag aaaataaatt gttagcagat
    72181 ggtattttgc aatcaagata ttttgaaaat ttgaaaaata gttggaaaga tttagatata
    72241 gctgtagtcg gaattggtga ttttagcaat aaaggaaagc atcaatggtt agacatgctt
    72301 acagaggatg actttaaaga attgaccaaa gttaaaactg taggagaaat ttgttgtcga
    72361 ttttttgatt caaaaggtaa agaagtctat gaaaacttac aggaaagaac gatagcaatc
    72421 tctttggaag atttaaaaaa tattcctcaa agtttagctg ttgcttacgg tgatacgaaa
    72481 gtatcttcga ttctttctgt cttgcgtgct aatttagtaa atcatttgat tacagacaaa
    72541 aatacaattt taaaagtttt ggaagaagat ggggatttga cttttagaga gattctaggt
    72601 gagtgaaaat gatagactga ttcagtttat cgtttttctt tttagttgat tgcacatttg
    72661 tgcttatata aacaaaaata gtttatctgt tgtttttgga ttgacaactt tattatgtag
    72721 ttgtattcta tagttacaaa agaaaatttt aaaatttcaa atgaaaaaag ctttttacat
    72781 agtgaaatga ggaggaattt atggaaatta ttgttccaga tcaaattatc atgggtttaa
    72841 ttttatatgc tggtgatgcg aaacaacata tttataaagc gttagattac ataaaaaatg
    72901 gtacatgtga acggtgtgaa gaagaaatcc agttagctga tgccgcctta ttagaagccc
    72961 ataatctaca aacaaaattc ttggcacaag aagcgtctgg tacaaagaca gaaattacag
    73021 ctctctttgt tcattcacaa gatcatctca tgactagtat gacggagatt aatttaatca
    73081 aagaaattat tagtttgaga aaagaacttc ataaaaaata atactagagt attatcattg
    73141 ttattaacat agaggaggaa aacataatgg tgaagattgg tttgttttgt gcagcaggtt
    73201 tttctactgg tatgcttgta aataatatga aaattgcagc gcaatctagt ggagttgagg
    73261 cagaaataga ggcgttttct cagtctaaat tagcggatta tgcgccaaat atagatgttg
    73321 cactattggg tccacaagtt gcttatacat tagataaatc aaaagaaatt tgtgataagt
    73381 gtgatgttcc gatagctgtt attccgatga tggactatgg tatgttagat gggaaaaaag
    73441 tattagattt ggccctatct ttgattagtg ggtaagaaaa ggagatttat tatgtcaaag
    73501 atggatgttc agaaaatcat tgcaccgatg atgaagtttg tgaatatgcg tggcattata
    73561 gctctaaaag atgggatgtt agcaattttg ccattgacag tagttggtag tttgttcttg
    73621 attatgggac aattgccgtt cgaaggatta aataagagca ttgctagtgt ttttggagct
    73681 aattggacag agccgtttat gcaagtatat tcaggaactt ttgctattat gggtctaatt
    73741 tcttgttttt caattgccta ttcttatgct aagaatagcg gagtagaggc tttaccagct
    73801 ggagttctat ctgtatctgc attctttatt ttgctaagat catcttatat ccctaaacaa
    73861 ggtgaggcga ttggggacgc tattagtaaa gtttggtttg gaggccaagg aattatcggt
    73921 gctatcatta taggtttggt agtaggaagt atttatacct tctttataaa gagaaagatt
    73981 gttattaaga tgccagaaca agttccacaa gctattgcca aacagtttga agcaatgatt
    74041 ccagcatttg taattttctt atcttctatg attgtatata ttttagcgaa gtcattgact
    74101 aatggcggaa cattcataga aatgatttat tctgctattc aagttccgtt gcaaggttta
    74161 actggatctt tgtatggtgc tattggaatt gcattcttta tatcattttt gtggtggttt
    74221 ggtgttcatg ggcaatcggt agtaaatgga gtagtgacag ctcttctttt atctaatctt
    74281 gatgctaata aagctatgtt agcctctgct aatctatcat tagaaaatgg agcacatatt
    74341 gttactcaac agtttttaga ttcattttta attctatcag gttcagggat tacgtttggt
    74401 cttgtagttg ccatgctttt tgcagcaaaa tcaaaacaat accaagcctt aggaaaagtt
    74461 gcagcttttc cagcaatatt taacgtaaat gagccagttg tatttggatt tccgattgtc
    74521 atgaatccag ttatgtttgt acctttcatt cttgttcctg tacttgcagc tgtgatagta
    74581 tatggagcta ttgcaacagg tttcatgcag ccattctcag gggtaacatt gccttggagt
    74641 acaccagcta ttctatcagg atttttggtg ggtggatggc aaggtgttgt gactcagtta
    74701 ttagtattgg tgatatctac agtggtttac tttccattct ttaagataca agatcgttta
    74761 gcttaccaaa atgaaatcaa acaatcttag aggtatttgt gtgttactgt taaactcaca
    74821 catttgtgct aaaaattaga gagttaaaat ttttctagtt aaaagcttga aaatttctat
    74881 aaaaatcggt attatatttt cgaaagaaat aaaaatattt tcgaaagaaa ggtgcttacg
    74941 atggtaaata cagaagtagc aagaacaaca atcaagacag aatattttgg cagccttact
    75001 gaaaggatga acaaatatcg agaagatgtt ttaaataaaa aaccttatat tgatgctgag
    75061 agagcagttc tagcaacacg cgcctatgaa cgatacaagg aacaacctaa tgtcctaaaa
    75121 cgtgcatata tgctgaaaga aattttggaa aatatgtcta tctatattga agaagaatct
    75181 atgattgcgg gaaatcaagc ttcttccaat aaagatgctc ctatttttcc ggaatatacg
    75241 ctagaatttg ttctcaatga gttggatctt tttgaaaagc gtgatggaga tgttttctat
    75301 attacagaag aaacaaaaga acaacttaga agtattgctc cgttttggga aaataataat
    75361 ttacgtgcta gagctggtgc cttattacct gaagaagtgt ctgtttatat ggaaacagga
    75421 ttcttcggta tggaaggtaa gatgaattct ggagatgctc acttagcagt taactatcag
    75481 aaacttttgc aatttggttt aagaggtttt gaagagcggg ctcgtaaagc aaaagtagct
    75541 ctagatttaa cagatccagc aagtattgat aaatatcatt tttacgactc tatatttatc
    75601 gtaatcgatg ctattaaagt atatgcaaag cgctttgttg ctcttgctaa aagtttagcc
    75661 gaaaatgcaa atcctaaacg taagaaagaa ttacttgaga ttgcagatat ttgctctaga
    75721 gtcccatatg aaccggcaac tacttttgca gaagctattc aatcagtttg gtttattcaa
    75781 tgtattttac aaattgaatc taatggccac tctctttcat atggccgttt tgatcaatat
    75841 atgtatccat atatgaaggc tgatttagaa agtggtaaag aaacagaaga tagcattgtt
    75901 gaacgtctga caaatctttg gattaagaca attacaatta ataaggttcg cagtcaatca
    75961 catacatttt cttcagcagg aagtccttta tatcaaaatg ttacaattgg tggacagact
    76021 cgagataaga aggatgctgt taacccatta tcttatttgg tcttaaaatc agttgcacaa
    76081 acccatctac cgcaacctaa tctaactgta cgttaccatg caggtttaga tgctcgtttc
    76141 atgaatgagt gtattgaagt gatgaaactt ggttttggta tgcctgcatt taataatgat
    76201 gagattatta ttccttcttt tattgcaaaa ggagtattgg aagatgatgc ttatgattac
    76261 agtgccattg gatgtgttga aacggcagtt ccagggaaat ggggctatcg ttgcacaggt
    76321 atgagttata tgaacttccc taaggttcta cttatcacga tgaatgatgg aattgatccg
    76381 gcttcgggta aacggtttgc accaagcttt ggtcatttta aggatatgaa gaacttttct
    76441 gaattagaaa atgcttggga taaaacacta agatatttga cacgaatgag tgttattgtt
    76501 gaaaattcta ttgatttatc attggaacga gaagttcctg atattctatg ttcagcattg
    76561 actgatgatt gtattggtcg tggaaaacac cttaaagaag gtggagcagt atatgattat
    76621 atatcaggat tgcaagttgg aattgcaaat ttgtcggatt cattagctgc aattaaaaaa
    76681 ttggtgtttg aggaagaacg tataagccca agtcagcttt ggcatgcact ggaaacagat
    76741 tatgccggag aagaaggtaa ggtcattcaa gaaatgttga ttcatgatgc acctaagtat
    76801 ggtaatgatg atgattatgc tgacaaattg gttactgctg cttatgacat ttatgttgat
    76861 gaaattgcta aatatcctaa tacacgttat ggaagagggc ctattggagg aattcgttat
    76921 tcaggaacat cttctatatc agccaacgta gggcagggac gtggaacatt agcaactcca
    76981 gatggacgca acgcgggtac accgttagca gagggttgtt caccatcaca taatatggat
    77041 caacacggcc ctacatctgt tttaaaatct gtttcaaaat taccaacaga tgaaatcgta
    77101 ggtggggttc tcttaaatca gaaagtaaat cctcaaacgt tagccaaaga agaagataaa
    77161 ttaaaactaa ttgctttgtt acgaacattc tttaatcgtt tacatgggta ccatattcaa
    77221 tacaatgttg tttccagaga gacgttgatt gacgctcaga aacatcctga aaaacacaga
    77281 gacttaattg ttcgtgttgc aggatactct gcattcttca atgttctttc taaggcaacc
    77341 caagatgaca ttataggacg tactgagcat actttgtaaa ataaagaggt tctttttatg
    77401 gaatttatgc ttgacacatt aaatttagat gagattaaaa agtggtctga aattttgccg
    77461 ctagctgggg taacttcaaa tcccactatt gcaaaaagag agggttctat taattttttt
    77521 gaacgaatca aagatgtaag agaattgatt ggctccacac cctctattca tgttcaggtg
    77581 atttctcaag attttgaagg catcttaaag gatgctcatg aaattcgaag acaagcagga
    77641 gatgatatat ttatcaaagt acctgttact ccagctggat tacgtgcaat aaaggtgcta
    77701 aaaaaagagg gctaccatat cactgcaaca gctatttata cagttattca gggattatta
    77761 gctatcgaag taggagcgga ttacctagct ccatattata atagaatgga aaatctgaac
    77821 attgattcaa attctgtcat tcgtcaatta gctcttgcta ttgatagaca gaactctcct
    77881 agtaagattt tagctgcatc ctttaaaaat gtagcacaag taaataatgc tttagctgca
    77941 ggtgcgcatg ctgttacagc aggagcagat gtttttgaat cagctttcgc catgccatct
    78001 atccaaaagg cggttgatga tttttctgac gattggtttg ttactcaaaa tagtcgttcc
    78061 atttagatag agaggaaata catatgagaa tttttgctag tccttctaga tatattcagg
    78121 gggaaaatgc cttgtttgaa aatgccaaat caattttgga tttgggaaat tacccgattc
    78181 tattatgcga tcagttggtt tatgatattg ttggaaaacg atttgaagat tatctacata
    78241 ggtatggttt ccatattgtt ctggcgctat ttaatggtga agcttctgac aatgaaatca
    78301 atcgagttgt tgccttggct gagaaagaaa attgtgatag tattatcggt cttggtgggg
    78361 gaaagacgat tgatagcgca aaagctattg cagatttgat tgaaaagcct gttattattg
    78421 ctccaacaat tgcatcgacc gacgcacctg tatctgcttt atctgttatt tatacagatg
    78481 aaggtgcatt tgatcattat ctattttatt ctaaaaatcc agatttagtt ttggttgata
    78541 caaaagttat ttcacaagcc cctaagcgtt tattagcgtc tggtattgca gatggtttag
    78601 caacttgggt tgaggcgcgt gcggttatgc aggcaaatgg aaaaactatg ttgggacaac
    78661 agcaaacatt ggctggagtt gcaattgcga agaaatgtga agaaacgctg tttgcagatg
    78721 gtttacaggc tatggcagct tgtgaagcta aagtggtgac accagcatta gaaaacattg
    78781 ttgaagctaa tactttattg agtggtttag gttttgaaag tggaggatta gctgcggcgc
    78841 atgcaattca taatggtttt actgcattga caggtgacat tcatcattta acacatggtg
    78901 aaaaagtagc ttatggaact ttagtacaac tattattgga aaatagacct aaagaagaac
    78961 ttgataagta tattgagttt tacaaaaaaa ttggtatgcc aacaactcta aaagaaatgc
    79021 atttggatca agttggatat gatgatttaa taaaagttgg taaacaagca actatggagg
    79081 gtgagacaat tcatcagatg ccgtttaaga tttcgccttc agatgttgct caagctatta
    79141 tcgctgtaga tgcctatgta aattcaaaat aaacaataag gactactgtt ttccaaatgg
    79201 tagtctttta ttgatcctcg tattgaattc tatagcagat tgaaataaga tgagaacaaa
    79261 tcgattggga aagtaaaatt aatttctata agtgttttag caattgtttc gtactatttc
    79321 agattcagtc cactatacgt tcttcataaa tcaaaaagcg acataggttg tcggctattt
    79381 attgtgaata cattaattag cattccagtt ttatcttcgg tctaaagtaa gtattttgtg
    79441 ctatacgaga taagcgtctt gacttactcc ttgatttact gcataacaat gggataaaaa
    79501 gtgggagata gagcaattca tagtcatcaa aattaatgag atacagtata cagttttttc
    79561 tttaaacaca tttcaaattc cctcaaaaat ggtataatag taacatcaca aaattggaga
    79621 gagaccatga gtttttataa tcataaagaa attgagccta agtggcaggg ctactgggca
    79681 gaacatcata catttaagac aggaacagat gcatcaaaac ctaagtttta tgcgcttgat
    79741 atgttccctt atccgtctgg agctggtctg catgtaggac acccagaagg ttatactgca
    79801 accgatatcc tcagtcgtta caaacgtgcg caaggctaca atgtccttca cccaatgggt
    79861 tgggatgctt ttggtttacc tgcagagcaa tacgctatgg atactggtaa tgacccagca
    79921 gaatttacag cggaaaacat tgccaacttc aaacgtcaaa tcaatgcgct tggattttct
    79981 tatgactggg atcgtgaagt caacacaaca gatccaaact actacaagtg gactcaatgg
    80041 attttcacca agctttacga aaaaggcttg gcctatgaag ctgaagtgcc agtaaactgg
    80101 gttgaggaat tgggaactgc cattgccaat gaagaagtgc ttcctgacgg aacttctgag
    80161 cgtggaggct atccagttgt ccgcaaacca atgcgccaat ggatgctcaa aatcacggct
    80221 tacgcagagc gcttgctcaa tgacttagat gaactagatt ggtcagagtc tatcaaggat
    80281 atgcaacgca actggattgg taaatcaact ggtgccaatg taactttcaa agtaaaagga
    80341 acagacaagg aatttacagt ctttactact cgtccggaca cacttttcgg tgcgactttc
    80401 actgtcttgg ctcctgaaca tgaattagta gacgctatca caagttcaga gcaagcagaa
    80461 gctgtagcag actataaaca ccaagccagc cttaagtctg acttggctcg tacagacctt
    80521 gctaaggaaa aaactggtgt ttggacaggt gcctatgcca tcaaccctgt caatggtaag
    80581 gaaatgccaa tctggattgc ggactatgtt cttgctagtt atggaacagg tgcggttatg
    80641 gctgtgcctg cccacgacca acgtgactgg gaatttgcca aacaatttga ccttccaatc
    80701 gtcgaagtac ttgaaggtgg agatgtcaaa gaagctgcct acacagagga tggcctgcat
    80761 gtcaattcag acttcctaga tgaactcaac aaagaagacg ctattgccaa gattgtggct
    80821 tggttggaag aaaaaggctg tggtcaggag aaggttacct accgtctccg cgactggctc
    80881 tttagccgtc aacgttactg gggtgagcca attccaatca ttcattggga agatggaact
    80941 tcaacagctg ttcctgaaac tgaattgccg cttgtcttgc ctgtaaccaa ggatatccgt
    81001 ccttcaggta ctggtgaaag tccactagct aacttgacag attggcttga agtgactcgt
    81061 gaagatggtg tcaaaggtcg tcgtgaaacc aacactatgc cacaatgggc tggttcaagc
    81121 tggtactacc tccgctatat tgatccacac aatactgaga aattggctga tgaggacctc
    81181 ctcaaacaat ggttgccagt agatatctac gtgggtggtg cggaacatgc tgtacttcac
    81241 ttgctttacg ctcgtttctg gcacaaattc ctctatgacc tcggtgttgt tccgactaag
    81301 gaaccattcc aaaaactctt taaccaaggg atgattttgg gaacaagcta ccgtgaccac
    81361 cgtggtgctc ttgtggcaac cgacaaggtt gaaaaacgtg atggttcctt ctttcatgta
    81421 gaaacagggg aagagttgga gcaagcgcca gccaagatgt ctaaatcgct caagaacgtt
    81481 gttaacccag acgatgtggt ggaacaatac ggtgccgata cccttcgtgt ttatgaaatg
    81541 tttatgggac cactcgatgc ttcgattgct tggtcagaag aaggtttgga aggaagccgt
    81601 aagttccttg accgagttta ccgtttgatt acaagtaaag aaatccttgc ggaaaacaat
    81661 ggtgctcttg acaaggttta caacgaaaca gtcaaagctg ttactgagca aattgagtct
    81721 ctcaaattca acacagctat tgcccaactt atggtctttg tcaatgctgc taacaaggaa
    81781 gataagcttt atgttgacta tgccaaaggc tttattcaat tgattgcacc atttgcacct
    81841 cacttggcag aagaactctg gcaaacagtc gcagaaacag gtgagtcaat ctcttatgta
    81901 gcttggccaa cttgggacga aagcaaattg gttgaagatg aaattgaaat tgtcgtccaa
    81961 atcaaaggaa aagtccgtgc caaactcatg gttgctaaag atatatcacg tgaagaatta
    82021 caagaaatcg ctttagctga tgaaaaagtc aaagcagaaa ttgacggtaa ggaaatcgtg
    82081 aaagtaattg cggtaccgaa taaactcgtt aatatcgtcg ttaaataacg agtttattag
    82141 ctctatctgc caccttcaat agtccactgg actattgaag ccaactaaat tagttaacat
    82201 tgttgtgaaa taagatagga atccttcaga gtagaatctg gaggattttt tgaaccttct
    82261 tatgaaagta tgatatatag tagactgaat ctaaaatagt acgaaacaat tgctaaaaca
    82321 tttatagaaa ttaattttac tttcccaatc gatttgttct catcttattt caatacgcta
    82381 tactatgggc aactataaag tttgaaaagc gaaacaagga gaaagttata ccagtaaacg
    82441 aatatggtca gatgattggt gagtcaatgg aaggttatac accaggtgaa ctgacttcta
    82501 ttgatctctt agaagggcgt tatgctagga tagaggctct ttcagtggaa aagcatgcgg
    82561 aggatttgct agctgtttat ggtcctgata ctcctcagga gatgtggacc tacctctttc
    82621 aggagccagt agcagacatg gaggaactgg tcagcctttt aaatcagatg ttggctcgta
    82681 aggaccgttt ttactatgca atcatagaca aggcaactgg taaggctttg ggaacttttt
    82741 ctctcatgcg tattggccag taacggagta atagaagtgg gagctgttac tttttctcca
    82801 aaactcaggg ggacacggat agggacagaa gcccagtatc tactggctcg ctatgtcttt
    82861 gaagagctta actatcgtcg ttatgagtgg aaatgcgatg ctcttaacct gccatccaga
    82921 cgtactgcgg agcgtttggg ctttatttat gaaggaacct tccgtcaggc agtggtttat
    82981 aaggggcgta cgagagatac ggattggttg tctatgattg ataaggactg gcccaaagtc
    83041 aaagatcgtt tggaaacatg gttgcgtcct gaaaattttg ataaaaatgg acagcagtac
    83101 aagagcttga gagagtttta agaggtgttg acatgatcac tattagaaag caagaaatcg
    83161 tcaagttcga ggatgttttg catctctatc aggctgtcgg ttggacaaat tatataaatc
    83221 aacatcagat gctggagtag accttgtatc attcattaat aatttatctg gcacttgatg
    83281 gtgatgctgt tgtgggcttg attcgtttgg ttggagatgg tttttcatca gtttttgtac
    83341 aggatttgat tgttttgtct agctatcagc gccaagggat tggtagctcc ttgatgaaac
    83401 aggctttagg aaattttaaa gaggcctatc aagtccagct ggcgacagaa cagacagaaa
    83461 aaaacgtgga atttaatcgt tctatgggct ttgaaatttt atccacctat aattggatag
    83521 ggatgacttg gatgaatcgt aaaaaataac aaaacttgtt ttttcttaag caaaatttaa
    83581 ggatggtcta gtattatata at
//
LOCUS       DBERDS010000003        80502 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.003, whole genome shotgun sequence.
ACCESSION   DBERDS010000003 DBERDS010000000
VERSION     DBERDS010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 80502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80502
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.003"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(381..1361)
                     /locus_tag="ACL73E_000203"
     CDS             complement(381..1361)
                     /locus_tag="ACL73E_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGS0800251.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1677..3692)
                     /gene="recG"
                     /locus_tag="ACL73E_000204"
     CDS             complement(1677..3692)
                     /gene="recG"
                     /locus_tag="ACL73E_000204"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGS0800252.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERETDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMIETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEVWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3711..4814)
                     /gene="alr"
                     /locus_tag="ACL73E_000205"
     CDS             complement(3711..4814)
                     /gene="alr"
                     /locus_tag="ACL73E_000205"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGS0800253.1"
                     /translation="MKASPHRPTKVLIHLGAIRQNIQQMGTHIPQGTLKWAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4804..5166)
                     /gene="acpS"
                     /locus_tag="ACL73E_000206"
     CDS             complement(4804..5166)
                     /gene="acpS"
                     /locus_tag="ACL73E_000206"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGS0800254.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(5211..6242)
                     /locus_tag="ACL73E_000207"
     CDS             complement(5211..6242)
                     /locus_tag="ACL73E_000207"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS0800255.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6244..7275)
                     /locus_tag="ACL73E_000208"
     CDS             complement(6244..7275)
                     /locus_tag="ACL73E_000208"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGS0800256.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7356..9869)
                     /gene="secA"
                     /locus_tag="ACL73E_000209"
     CDS             complement(7356..9869)
                     /gene="secA"
                     /locus_tag="ACL73E_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGS0800257.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKKRYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10063..10302)
                     /locus_tag="ACL73E_000210"
     CDS             complement(10063..10302)
                     /locus_tag="ACL73E_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800258.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLVFGILSILMALLSKKVSLFVFGLICCLSL"
     gene            complement(10330..10962)
                     /locus_tag="ACL73E_000211"
     CDS             complement(10330..10962)
                     /locus_tag="ACL73E_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0800259.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10966..11607)
                     /locus_tag="ACL73E_000212"
     CDS             complement(10966..11607)
                     /locus_tag="ACL73E_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800260.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11600..12391)
                     /locus_tag="ACL73E_000213"
     CDS             complement(11600..12391)
                     /locus_tag="ACL73E_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800261.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12576..12911)
                     /locus_tag="ACL73E_000214"
     CDS             complement(12576..12911)
                     /locus_tag="ACL73E_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800262.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     SLFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVRH"
     gene            complement(13051..13386)
                     /locus_tag="ACL73E_000215"
     CDS             complement(13051..13386)
                     /locus_tag="ACL73E_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800263.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13477..14787)
                     /gene="der"
                     /locus_tag="ACL73E_000216"
     CDS             complement(13477..14787)
                     /gene="der"
                     /locus_tag="ACL73E_000216"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGS0800264.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14801..15514)
                     /locus_tag="ACL73E_000217"
     CDS             complement(14801..15514)
                     /locus_tag="ACL73E_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGS0800265.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15511..16407)
                     /gene="dnaI"
                     /locus_tag="ACL73E_000218"
     CDS             complement(15511..16407)
                     /gene="dnaI"
                     /locus_tag="ACL73E_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGS0800266.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16408..17577)
                     /locus_tag="ACL73E_000219"
     CDS             complement(16408..17577)
                     /locus_tag="ACL73E_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS0800267.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRDR
                     GQKAKTQKQNQTAPEKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17578..18051)
                     /gene="nrdR"
                     /locus_tag="ACL73E_000220"
     CDS             complement(17578..18051)
                     /gene="nrdR"
                     /locus_tag="ACL73E_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGS0800268.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18191..18556
                     /locus_tag="ACL73E_000221"
     CDS             18191..18556
                     /locus_tag="ACL73E_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0800269.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18561..19256
                     /locus_tag="ACL73E_000222"
     CDS             18561..19256
                     /locus_tag="ACL73E_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800270.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19273..20040
                     /locus_tag="ACL73E_000223"
     CDS             19273..20040
                     /locus_tag="ACL73E_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800271.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20393..21592)
                     /locus_tag="ACL73E_000224"
     CDS             complement(20393..21592)
                     /locus_tag="ACL73E_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800272.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVEVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21589..22482)
                     /locus_tag="ACL73E_000225"
     CDS             complement(21589..22482)
                     /locus_tag="ACL73E_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800273.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22605..22796
                     /locus_tag="ACL73E_000226"
     CDS             22605..22796
                     /locus_tag="ACL73E_000226"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800274.1"
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            23189..23377
                     /locus_tag="ACL73E_000227"
                     /pseudo
     CDS             23189..23377
                     /locus_tag="ACL73E_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23792..24409
                     /locus_tag="ACL73E_000228"
     CDS             23792..24409
                     /locus_tag="ACL73E_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGS0800275.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24452..25339)
                     /gene="scrK"
                     /locus_tag="ACL73E_000229"
     CDS             complement(24452..25339)
                     /gene="scrK"
                     /locus_tag="ACL73E_000229"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGS0800276.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25488..27425)
                     /locus_tag="ACL73E_000230"
     CDS             complement(25488..27425)
                     /locus_tag="ACL73E_000230"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGS0800277.1"
                     /translation="MDYSKVAAEVIEAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLIGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGNAVIEVKI"
     gene            27801..29255
                     /locus_tag="ACL73E_000231"
     CDS             27801..29255
                     /locus_tag="ACL73E_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS0800278.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQNLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29236..30201
                     /locus_tag="ACL73E_000232"
     CDS             29236..30201
                     /locus_tag="ACL73E_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0800279.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30236..31510)
                     /locus_tag="ACL73E_000233"
     CDS             complement(30236..31510)
                     /locus_tag="ACL73E_000233"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGS0800280.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31510..32682)
                     /locus_tag="ACL73E_000234"
     CDS             complement(31510..32682)
                     /locus_tag="ACL73E_000234"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGS0800281.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLNKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32813..33061)
                     /locus_tag="ACL73E_000235"
     CDS             complement(32813..33061)
                     /locus_tag="ACL73E_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800282.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33129..33754)
                     /locus_tag="ACL73E_000236"
                     /pseudo
     CDS             complement(33129..33754)
                     /locus_tag="ACL73E_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(33816..34265)
                     /locus_tag="ACL73E_000237"
     CDS             complement(33816..34265)
                     /locus_tag="ACL73E_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS0800283.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(34267..35025)
                     /locus_tag="ACL73E_000238"
     CDS             complement(34267..35025)
                     /locus_tag="ACL73E_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGS0800284.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(35141..37120)
                     /gene="stkP"
                     /locus_tag="ACL73E_000239"
     CDS             complement(35141..37120)
                     /gene="stkP"
                     /locus_tag="ACL73E_000239"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGS0800285.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(37117..37857)
                     /locus_tag="ACL73E_000240"
     CDS             complement(37117..37857)
                     /locus_tag="ACL73E_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGS0800286.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(37872..39185)
                     /gene="rsmB"
                     /locus_tag="ACL73E_000241"
     CDS             complement(37872..39185)
                     /gene="rsmB"
                     /locus_tag="ACL73E_000241"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGS0800287.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFTNGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(39178..40113)
                     /gene="fmt"
                     /locus_tag="ACL73E_000242"
     CDS             complement(39178..40113)
                     /gene="fmt"
                     /locus_tag="ACL73E_000242"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGS0800288.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKSEEEKLNWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(40126..42522)
                     /locus_tag="ACL73E_000243"
     CDS             complement(40126..42522)
                     /locus_tag="ACL73E_000243"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGS0800289.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFDSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQMVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(42588..42902)
                     /gene="rpoZ"
                     /locus_tag="ACL73E_000244"
     CDS             complement(42588..42902)
                     /gene="rpoZ"
                     /locus_tag="ACL73E_000244"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGS0800290.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(42927..43553)
                     /gene="gmk"
                     /locus_tag="ACL73E_000245"
     CDS             complement(42927..43553)
                     /gene="gmk"
                     /locus_tag="ACL73E_000245"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGS0800291.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(43683..45296)
                     /locus_tag="ACL73E_000246"
     CDS             complement(43683..45296)
                     /locus_tag="ACL73E_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGS0800292.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(45487..45741)
                     /locus_tag="ACL73E_000247"
     CDS             complement(45487..45741)
                     /locus_tag="ACL73E_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGS0800293.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(45745..45999)
                     /locus_tag="ACL73E_000248"
     CDS             complement(45745..45999)
                     /locus_tag="ACL73E_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGS0800294.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSIQVHVIEE"
     gene            complement(46237..47334)
                     /locus_tag="ACL73E_000249"
     CDS             complement(46237..47334)
                     /locus_tag="ACL73E_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS0800295.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHTIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
     gene            complement(47344..48084)
                     /locus_tag="ACL73E_000250"
     CDS             complement(47344..48084)
                     /locus_tag="ACL73E_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0800296.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(48193..48546)
                     /gene="rsfS"
                     /locus_tag="ACL73E_000251"
     CDS             complement(48193..48546)
                     /gene="rsfS"
                     /locus_tag="ACL73E_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGS0800297.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(48559..49059)
                     /locus_tag="ACL73E_000252"
     CDS             complement(48559..49059)
                     /locus_tag="ACL73E_000252"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS0800298.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(49060..49653)
                     /gene="yqeK"
                     /locus_tag="ACL73E_000253"
     CDS             complement(49060..49653)
                     /gene="yqeK"
                     /locus_tag="ACL73E_000253"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGS0800299.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(49653..50282)
                     /locus_tag="ACL73E_000254"
     CDS             complement(49653..50282)
                     /locus_tag="ACL73E_000254"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGS0800300.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(50334..50645)
                     /gene="yhbY"
                     /locus_tag="ACL73E_000255"
     CDS             complement(50334..50645)
                     /gene="yhbY"
                     /locus_tag="ACL73E_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGS0800301.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(50860..51966)
                     /gene="yqeH"
                     /locus_tag="ACL73E_000256"
     CDS             complement(50860..51966)
                     /gene="yqeH"
                     /locus_tag="ACL73E_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGS0800302.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAYEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(51969..52496)
                     /locus_tag="ACL73E_000257"
     CDS             complement(51969..52496)
                     /locus_tag="ACL73E_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGS0800303.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            complement(52511..53419)
                     /locus_tag="ACL73E_000258"
     CDS             complement(52511..53419)
                     /locus_tag="ACL73E_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGS0800304.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(53476..54036)
                     /locus_tag="ACL73E_000259"
     CDS             complement(53476..54036)
                     /locus_tag="ACL73E_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGS0800305.1"
                     /translation="MQKFIQAYIEKLDVTSIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            54175..55393
                     /gene="sstT"
                     /locus_tag="ACL73E_000260"
                     /pseudo
     CDS             54175..55393
                     /gene="sstT"
                     /locus_tag="ACL73E_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            55461..56414
                     /locus_tag="ACL73E_000261"
     CDS             55461..56414
                     /locus_tag="ACL73E_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS0800306.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            56558..56938
                     /locus_tag="ACL73E_000262"
     CDS             56558..56938
                     /locus_tag="ACL73E_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS0800307.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            57038..57259
                     /locus_tag="ACL73E_000263"
     CDS             57038..57259
                     /locus_tag="ACL73E_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS0800308.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            57276..57590
                     /gene="trxA"
                     /locus_tag="ACL73E_000264"
     CDS             57276..57590
                     /gene="trxA"
                     /locus_tag="ACL73E_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS0800309.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            57896..58429
                     /gene="queF"
                     /locus_tag="ACL73E_000265"
     CDS             57896..58429
                     /gene="queF"
                     /locus_tag="ACL73E_000265"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGS0800310.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKPLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(58639..59307)
                     /locus_tag="ACL73E_000266"
     CDS             complement(58639..59307)
                     /locus_tag="ACL73E_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGS0800311.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(59418..60209)
                     /locus_tag="ACL73E_000267"
     CDS             complement(59418..60209)
                     /locus_tag="ACL73E_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGS0800312.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWIHSFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            complement(60634..61398)
                     /locus_tag="ACL73E_000268"
     CDS             complement(60634..61398)
                     /locus_tag="ACL73E_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800313.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAILMTPIN
                     TSDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(61391..62161)
                     /locus_tag="ACL73E_000269"
     CDS             complement(61391..62161)
                     /locus_tag="ACL73E_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800314.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            62410..63087
                     /locus_tag="ACL73E_000270"
     CDS             62410..63087
                     /locus_tag="ACL73E_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGS0800315.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            complement(63147..64943)
                     /gene="pepF"
                     /locus_tag="ACL73E_000271"
     CDS             complement(63147..64943)
                     /gene="pepF"
                     /locus_tag="ACL73E_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS0800316.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFENFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(64954..65697)
                     /locus_tag="ACL73E_000272"
     CDS             complement(64954..65697)
                     /locus_tag="ACL73E_000272"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGS0800317.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(65699..66649)
                     /gene="prmA"
                     /locus_tag="ACL73E_000273"
     CDS             complement(65699..66649)
                     /gene="prmA"
                     /locus_tag="ACL73E_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGS0800318.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            complement(66785..67213)
                     /locus_tag="ACL73E_000274"
     CDS             complement(66785..67213)
                     /locus_tag="ACL73E_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0800319.1"
                     /translation="MELEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(67194..68282)
                     /locus_tag="ACL73E_000275"
     CDS             complement(67194..68282)
                     /locus_tag="ACL73E_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGS0800320.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKEMLEGTEDGTRNF"
     gene            complement(68301..68771)
                     /locus_tag="ACL73E_000276"
     CDS             complement(68301..68771)
                     /locus_tag="ACL73E_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGS0800321.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKIGLEKGEFYPYPKY"
     gene            complement(69062..69514)
                     /locus_tag="ACL73E_000277"
     CDS             complement(69062..69514)
                     /locus_tag="ACL73E_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGS0800322.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(69551..69730)
                     /locus_tag="ACL73E_000278"
     CDS             complement(69551..69730)
                     /locus_tag="ACL73E_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGS0800323.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            complement(69867..70046)
                     /locus_tag="ACL73E_000279"
     CDS             complement(69867..70046)
                     /locus_tag="ACL73E_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800324.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(70211..70432)
                     /locus_tag="ACL73E_000280"
     CDS             complement(70211..70432)
                     /locus_tag="ACL73E_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800325.1"
                     /translation="MEMMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEI
                     LDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            70724..71995
                     /locus_tag="ACL73E_000281"
     CDS             70724..71995
                     /locus_tag="ACL73E_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGS0800326.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            72260..72332
                     /locus_tag="ACL73E_000282"
     tRNA            72260..72332
                     /locus_tag="ACL73E_000282"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72293..72295,aa:Lys,seq:ctt)
     gene            complement(72540..73859)
                     /locus_tag="ACL73E_000283"
     CDS             complement(72540..73859)
                     /locus_tag="ACL73E_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGS0800327.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(73869..75485)
                     /locus_tag="ACL73E_000284"
     CDS             complement(73869..75485)
                     /locus_tag="ACL73E_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0800328.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKATDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTIPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSNYLAIKQKYYDQYQANKN"
     gene            complement(75514..76404)
                     /locus_tag="ACL73E_000285"
     CDS             complement(75514..76404)
                     /locus_tag="ACL73E_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0800329.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            complement(76415..77332)
                     /locus_tag="ACL73E_000286"
     CDS             complement(76415..77332)
                     /locus_tag="ACL73E_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800330.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYDYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            complement(77482..78483)
                     /locus_tag="ACL73E_000287"
     CDS             complement(77482..78483)
                     /locus_tag="ACL73E_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0800331.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            complement(78844..80325)
                     /gene="mgaSpn"
                     /locus_tag="ACL73E_000288"
                     /gene_synonym="mgrA"
     CDS             complement(78844..80325)
                     /gene="mgaSpn"
                     /locus_tag="ACL73E_000288"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGS0800332.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
BASE COUNT        23415 a        18073 c        14989 g        24025 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttgaaga gatttttgaa aagtattaac
       61 acctacagac aagcctgacg atagcaagaa ctaccctact cgataggtat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 ataatagatt gaaactagaa tagtacacat ttgtttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gaccgatttg tcctgttctt atttcatttt actatatttc catgataaaa
      301 cgcatagtat aaagttttct taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atgcgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattagtg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aggtgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga aggataaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaagagcat ttcgctctct cttctgttta tactagtttt ttgcttcctt cttttggaaa
     1561 gtggtttggt aatttacttt aatcgttact gtcatatgag agtcctcgtt tctttttgat
     1621 gactttagta taagagccaa acctaaaaac tagcttaagt tttccttaga gaaagcttaa
     1681 tccagatgtt ctttcttttc cagatgaagg gcaatcatgc gccactctgg atcttcttgc
     1741 caaacttcta tagaactaat gtagctagca acctttcttg cttcttctaa aatcggaaaa
     1801 tcttcgataa tatcagccac ttggaactct ggaagtcctg actgtctggt tccaaaaatc
     1861 tcaccagaac cacgcatttt caaatcttcc tccgcaagga caaatccatt ggtcgtttct
     1921 atcatgatgc gcatgcggtc tttcccagaa tccgtcttgg gattggcaac gagaacagcg
     1981 taggactgct tgtccccccg accgacacga cctctaagct ggtgaagttg actgagaccg
     2041 aagcgatcgg catccatgat aatcatgaca gtcgcattgg gaacgttgac cccaacctca
     2101 ataaccgtcg tcgaaaccag aatatccgtc tctctctcct tgaaatcctg catgatctgg
     2161 tctttttcgt cactcttcat cctaccatgt agaagagcca cctctgcctt gcctgcaaaa
     2221 tgagtcgtca actcctctga taaggcaatg gcatttttca aatctagagc ttctgattct
     2281 tcaatcaaag gagagatgac atagacttgg gaaccttttt gaatttcccc ctctaaccaa
     2341 gtcaagacct gaggtagttg ctcatgtttg atccagcgcg tcacaatagg cttccgacct
     2401 gctggcatct ggtcgataat ggaaacatcc atatctccaa aggctgtgat ggcaagcgtc
     2461 cgtggaatgg gagtcgccgt catcatgagg acatctggat tgtcaccttt ttcccgtaaa
     2521 atacgccttt gccctacacc aaaacggtgc tgctcatcga taataatcaa accaagacga
     2581 gcatactcca ccccatcttg tatcagagcg tgagttccta taatcaaatc agcctcaccc
     2641 ttggcaatgg tctccaagac ctctctcttt tctgcagctt tcaaggaacc tgtcaagaga
     2701 gccagtttca aattgggaaa aaggttctgt aaactctcaa agtgttgctc tgcgaggatt
     2761 tctgttggta ccattagggc agcctgataa cctgctgtca ctgccgcaaa catggccaag
     2821 ccagcgacta ccgtttttcc actccccaca tccccttgta ggagacgatt catgtggtgg
     2881 tcggacttca tatcagttaa aatttcctgc aaactctttt cctgagcttg ggtcagggca
     2941 aaaggaagac ttactttaac tgctgtcact ttttcctgag accaattcag aaccagacca
     3001 cttccctgaa ctctattttc agacttgagc atctgcagct gcatttggaa ataaaagagt
     3061 tcctcaaact ttatacggcg aagagcctgc ttgtattctg ccaaatcctt tggaaaatgc
     3121 atagctcgga ctgcctgaca acgggacatg agtttgtatt tgtctagtaa agactggggc
     3181 agattttctt ctatcaagag gtccagtccc tgatcaaaag ccgtcttgat gaccttaacc
     3241 agactggcct gactgattcc ctgagccaga cgataaacag gctggaggtc atcttctacc
     3301 tgagccagaa ccttcatccc attcagacta gccttagcgc ggtcccattt tccaaagaca
     3361 gcaagggttg ctcccaactc tattttatca gccagatagg gctggttaaa gaaattcacc
     3421 gcaaaaacga cctctccctg cttgagacta aaacgcaggc gattgcgctt gaaaccataa
     3481 tactggacac tagcaggagt cactacctga ccagaaagaa ctgccttctc accgtcttcc
     3541 agctccagca cctgcttggt tttgaagtct tcataacgga aaggaaagta gagcaagaga
     3601 tcttgcaagt tttcaattcc tagtttggcg tatttttctg ctgactttgg tcccacacca
     3661 ggcaagacat gcaagggttg atgtagattc atgctccact cctttctttt ctaataatat
     3721 tctctcggaa tacggtcgct gaggaggcaa accacctcat agttaatggt tacgcggtag
     3781 gtcgctacct gagttgcagt gatttcctta tccccattgg agccaatcaa ggttaccttg
     3841 gttcctagcg gataaagctt aggcaatcga atagtgattt ggtccatcga aaccctgccg
     3901 acaattgggc aagcttggcc atctaccaag acagagaaat tttgcatgtc tcttgtccat
     3961 ccatctgcat acccgattgg cacggtcgcg atgacttgct cgctatccgc ttgataagtt
     4021 gctccatagc ccatgcaagc tcctgctgga actgtcttga catgaaccag agcagactcc
     4081 aaggtcaagg ccggtatcaa atcataaggc aaatccaaga ccgctccact tggattgagg
     4141 ccatacatgg catctcccat acgaaccgca ttgaaaatag tctctacatg ccaaagagtc
     4201 gttgcagaat tgctagcatg aaccagctct ggaacttcct tcatactagc taaaatagtt
     4261 ttaaaccgtt ctaactgggc attaaaatag tcatctgatt cctcatcagc agtagcaaag
     4321 tgggtaaaga ttccttcaac acgaacaccg tgttgttgta gcaaatcttg agcctgctca
     4381 acctcactgg cctctctaaa accaatccgt cccatccctg aatcaatctt gaggtggact
     4441 gtcaatccag ttaggtccac ttccttatct aagagtgctt gaatccactc cagtccagcc
     4501 actgtcaagg tgaagtcata ttctttagct agagcaacag cttcgatttc agaaactcct
     4561 aaaatgagga ttggcttgct gagtccagct tgtctgagtt caatggcttc atcgatattg
     4621 gaaacgcaaa agccatcaac atcatcttga attgccttgg caacggcaac agctccatga
     4681 ccataagcat tggccttgac cacagcccac ttgagcgttc cttgagggat atgagtcccc
     4741 atttgctgaa tattttgtcg aatagctccc agatgaatca gaaccttggt tggtctatgt
     4801 ggactagctt tcatgatttt cctccaaaat gacactggct gtcacaaact gatcggtgtg
     4861 gctgatagac agccaaatct ttcctgaaaa tggtgcctga ctaaaataag gcgccccacg
     4921 ttcattgttc aatacttcca aatcctgaaa accgagcttg ctaatgcccg ttcccatagc
     4981 cttggaaaag gcctccttag ccgaccagcg accagctaaa tattctattt gcctgcgtcc
     5041 tttgagactg gtgaagcgct ccatttcctg agcagtcagt acacgcttag caaatccttc
     5101 atgtcgtgta actgcgcttt ctatcgaagc caattcttcg atgtcaattc cgtgtccaac
     5161 tatcattttc atcaaaagga gttgagattc cccaactcca tccttttcac ttattttgtc
     5221 aaggtaacat aaatctcttc taccaaggcc tctgtatttt cccaacctag gcaagggtca
     5281 gtaatagagc aaccaaagat ctctggttgg ttttgacgac catctgctag gtaagattca
     5341 atcataaatc ctcgaaccgt ctttttaatt ttctcattcc aatcacgatt ctgcaaggtc
     5401 tggcgaacaa ttcgaatctg ctccatatat tgcttgcctg agttatcatg gttggtgtca
     5461 atgaggataa aaggattttc aagtcccatg gtttcatagc gttcaatggc ttggagtagg
     5521 ttttcatagt agtaattcgg catataattg ccatactcgt tgactgctcc acggaggata
     5581 acatgggcca aaggattacc tgatgtctca acttcctgcc catgataaag gaaggtttgc
     5641 ttgttttgag cagcatagat ggcgttaaac ataacaccca aatttcctga ggttggattt
     5701 ttcatcccta ctggtgcatc aatcccagaa gccacaaagc ggtgctcttg gtcttccaca
     5761 gaacgagctc caacggcatg gtagctgacc aagtcatcca ccaagatcag atttgacgga
     5821 taaagcatct catctgccgt tgttaaacca gtctctgtaa tcacgcggta gtgcaactgg
     5881 cgcacagcct gcaagccgtt aatcaggctt ggagccttag aagtatctgg ctggtgaacc
     5941 aatcctttat agccgtctcc attggtacga ggcttagcag tatacacgcg catgaccatg
     6001 aaaatcttat ccgctacctt cttttgcaag gcggataaac ggcgagcata ttccaagacc
     6061 gcctcttcat tatcagaaga gcaaggacca atcaccaaga gaatacggtc atcttcccct
     6121 gaaataatat ctgccaattc cctgtcacgg ctttccttga gtctcaaggc ttccgcagac
     6181 aattgggttt cagccttgat gacttccata tcgatttctt gacctttttc aataaatgcc
     6241 atcttattct cctaacgttt tgtaaatttc tctgacaaga gcttctgtgt tatcccaacc
     6301 caggcaaggg tctgtgatag acttaccaaa tacttctggc tcattttgtc gaccatcttc
     6361 cagataagac tcaatcataa aaccacgaac gaactgctta attttttcat tccaagcacg
     6421 gttaatcaag gtctggcgga caattcggat ctgttcaata tactgcttac cagaattgtc
     6481 atgattggta tcaatgatga taaaaggatt ttccaagccc attttctcat actgggcaat
     6541 ggtatcaatt aaattgtcat aatagtagtt gggaatattt tttccatact cattaagagc
     6601 accacgaaga atagcgtgtg aaagcgggtt cccagttgtt tctacttctt ttcctaagaa
     6661 aaggaaactt tgtttgtttt gagcagcata aattccatta aacatgacat tgagatttcc
     6721 agaggttgga tttttaaaac cagtagaaaa tcctgcccca cttgccacaa agcggtgttg
     6781 ctggtcttca actgaacggg caccaactgc catgtaagaa atcaaatcat ctacaagcgg
     6841 aaggttttca ggataaagca tttcatcagc agttgtcatc cctgtttctg tgatgacacg
     6901 atagtgaaga tggcgaacgg ctttgattcc attgataaga ctaggcgctt ctgtcgcgtt
     6961 aggctggtga atcaagccct tatagccatc tccgttggta cggggtttgg cagtataaac
     7021 acgcataacc ataaagatac gatctgccac ttcttcttgt aggactgcca aacgcttagc
     7081 gtattcaagg acagcttctt cgttgtcaga tgagcatggc ccgattacca agagaattcg
     7141 ctgatcttct ccacgtataa tggcttctag ctcttgatct cgctgtgatt tcctctccaa
     7201 agcctgacct tctaattttg acaaggcacg aacttcttct atatttattt tagagctttt
     7261 tgctgtaaat accataactc atctccttat aaagcaaacg gatacccagt aaaaatttac
     7321 ttttcacaag atatccgcct ctaaactatc tcattttatt gtcttttacc gtgacagttt
     7381 ttaaatttct taccagaacc acatgggcaa agttcattgc gtccaatctg gctcaaatcc
     7441 aaatcttctg gcatacttgc ttggtgagca gcgatattgc gagtcgctgt tgtactgata
     7501 tgacgttctg cctgtggtct ttcttgttca tgaatttgtg ctttcatcat caagcgtgtc
     7561 acatcaaact caatcgaacc aatcatatca ttaaacatac ggaaaccttc tgcctgatac
     7621 tcaacaacag ggttgttctg agcatagcca cgaagtccaa ccgcgttacg caattgatca
     7681 agggcatcga tatgatctgt ccacttgtta tccaccactc gtagaatcaa aactttttgg
     7741 aattctttaa ctgcttcttc atcgcgtagt tttgaaacct gactatcgta aaccttcaag
     7801 gcacgttgga aaagctcttc cttgatggcc ttatcagaca agcctgacaa gtcttccatc
     7861 gtaatagaat cttcaggaag caagttgtac ttagcaaagt tcaaaattgc ctctagtttt
     7921 tcatcttgtt tagcacgcgc atgaccgtca acgacacgtt caatcgtgcg tttgatcata
     7981 gactgaattt caggtgccaa gtcacgatct gcagtgatga catcgtaacg ttgagcatag
     8041 ataatctcac gttgttcacg catgacatca tcgtattgaa ggacttgttt acgggtatcg
     8101 tagttatttc cttcgacacg tttctgagct gcttcaacct gacgcgtcaa catgcgagac
     8161 tcaatcgcct cttcagacat gttgagacgt tcaaagattc ccttcaagcg ttcagaacca
     8221 aaacgtttca tcaaatcatc ttcaagagat aggtagaatt gtgactcacc tggatctcct
     8281 tgacgacctg aacgtccacg aagctggtta tcgatacgac gactttcatg acgttctgta
     8341 ccaataacac aaagtcctcc aagttcacga acaccttcac caagcttgat gtcggtacca
     8401 cgacccgcca tgttggttgc gatggtaacg gcaccacgtt gaccagcatt catgatgatt
     8461 tgggcttctc tatagtggtt tttggcattc aagacttcgt gaggaacacc agctgcgacc
     8521 aatttcttag aaatgtagtc actagtttca accgctactg taccaaccaa gacaggttga
     8581 cccttttggt aacgagcctt aacgtcttcg acaaccgctt taaacttaga ttcgatactt
     8641 gcataaagaa ggtctgagtg gtcaatacgt tgaacaggac ggtttgttgg gattggaata
     8701 acacgaatgt tgtagatttc acggaattct tcttcctcag tcttacctgt acccgtcata
     8761 ccagacaatt tcttgtacat acggaagagg ttttggtacg tgattgaggc agatgtcttg
     8821 gtttcatcct ggattggcac accttctttg gcttcaatag cttggtgcaa tccatcagaa
     8881 taacgacgac cttccatggt acgacctgta aattggtcga caatcaagat ttcttgctct
     8941 tcgctcacca catagtcaat atcgagaagc atgatgtagt tggcacgaag ggcgttatcg
     9001 ataaagtggg tcaaagccac gttttcgatg tcatagaggt tttcaagttt gaagtagctt
     9061 tcagccctgt caatccctga atcagacaaa ccaatagtct tagactgcac atcgatgatg
     9121 tagtcatctt tgttcaaaga ttttacatag tggtctgcca tgtgatacaa ctgactggtt
     9181 tcaaccgcat tggcacctga tacaatcaaa ggtgtacgag cctcgtcaat caagatagag
     9241 tcaacctcat cgaccaaggc atagttaagc ggacgttgta ccatgttttc agcgcgaacg
     9301 accatgttgt cacgaaggta gtcaaatccg atttctgagt tagttgagta agtaatatca
     9361 cactcatagg cttctttttt ctccattgga gatttggtag ccaagttaat ccctactgac
     9421 aaaccaagcc aagagtacaa ttcacccatc tcagtcgcgt cacgttctga caggtattca
     9481 ttaaccgtaa ctacgtgaac ccctttacct gaaagggcat tgaggtatac cggcatggtc
     9541 gcagtcaagg ttttcccttc ccctgtacgc atctctggca cgtcaccatg gtgaagaaca
     9601 atccccccca tgacctgaac cttataaggg aagagaccta ggacacgttt ggcaccttca
     9661 cggacaaccg caaatgcttc gtaaagcaat gaatccagtg attctccatt ttgataacgt
     9721 ttcttaaatt caactgtttt tgcttttagt tggtcgtcag tcaaagcagc catttggtct
     9781 tcgtatttga aaaccttgtc agccatcttt tccagacgac ggatttctcc tttatcattt
     9841 tcgataattg tttttaaaat attagccatg tttttcctta ctttaaattc cgaatatttt
     9901 agaatgttcc tttaatttta gcacaattac tgattatttt caaggaagaa tccccatttt
     9961 gaaaaggaaa aagaggttag ttttcaagct aacctctccg acttttatga ctgtttaatt
    10021 gccaaaaatt ggcaaaatgg caaatgtgat aaataagtta attcaaagag aaagacagca
    10081 aatcagtcca aaaacaaaga gactgacttt cttggacagc aaggccatca aaatggacag
    10141 aattccaaaa actagcaaga ttttctgtat gatgaagatg tcaatcctta cccccagaat
    10201 cgctctatcc caagggataa agaagaaaga cagccagatc agcagaacta aaccaatata
    10261 aaccttggaa tagcgtgtaa taaatgattt tagatgtgcc acaagccatc tcctaggatt
    10321 gtatatcctt tacatttgta tatgtccatt ttcgacaact aatacatctg tacaaaggtc
    10381 tgaaatatct tccgatatgt gcgacgtcag gataaccaga ccattttctt ttttcaggta
    10441 agataaaatg acctgtttgg ttaacctcac actcttctca tccaaagcat tcataggttc
    10501 atcgagaaag agtatagaag gagaggaaat aaaggcttga atcaaggcca ttttttgctt
    10561 tgttcccaag gataaatgcc ggtattcaac gtcttcaaat tcctgtaaat catagtattg
    10621 aatccaatag gcaattcttt tttccgtaac tttagatgaa aaatacctta acagttccaa
    10681 attttctctc agggataaat gagataaaaa ctcgactttt tcaattaaaa ttcctgcatc
    10741 ctgaatataa tgatttttta tcccgtaaac tttaccatct tgaagaactt ttcctttgtc
    10801 aagcttaata taaccagcaa gtacctttaa aagaaccgtc ttgccagatc cattatcacc
    10861 tttaagtcca taaatttttc ctgattgaaa caccaaattc aactgattta aaataggtct
    10921 tttcccataa attttctgtc catttataat ttcaagtttc atcgtttatc ctttcttaaa
    10981 tttctcttcc aagcgactaa caatcaacat aactaataag cttaagagta gtaaatacac
    11041 tgttacaata tgatccatca tccattcttg tcccacaaat gctaaaaaat agagaaaaaa
    11101 ggaaaaacca gcgcccgcac taatcagtgc tatcagataa gacagtagta agtacaacat
    11161 cattaactga gcaagtaaaa agaaaagtgc gactgttttg aaatgaattc ctagcggaag
    11221 taaaccaagg aaccagacaa gtaaatcttg agtaaaaaat ttagaaatga caaccaatcg
    11281 tttccttgta taatcgaaaa aggagcttga ttgatagcga atcaagtgat ggtaatggtc
    11341 tgccaaatca ctttcaagta aaatgacaga gagccatcct accatgaaaa gcgaaaggtt
    11401 taacaagagt ttggggattt ctaaattcgc ttcagaatag tcattatagg aaaagattga
    11461 aatcaattct ctcttgaaaa agataacagc atcctgcttt tgaaccgctg ttgacaatag
    11521 atagtttatc aaaatcatca tcagaactat acgaagtagt aaaacgatct ttctctttag
    11581 ccaaatattg ttaaaattct taaacattat cttcatattt ttcaagcacc atataaggga
    11641 caatataaag gatataagga gtaaagagtt tcatcaaact tacatcccca tagctagctt
    11701 gcatcaaact cgtcatagga accatatagt aaggcaaggc actatagagc agcatagaac
    11761 caagccaaag aaacatcaaa taggtgattg ccgaacgagt cacattcccc acataatcaa
    11821 ctatttgtaa aaaatagatt gcattgatga aaataccgat tagtaggaca caagtaaaga
    11881 acaaatagct ttttatctct ccatctagga gtctttgtaa accacttcca tcagaaaata
    11941 gagaattcca tccaagagga gaaaaagtcc caaagaaata ggttataatt gcaattatca
    12001 gcacagtcac taaatatatc aaacaaggga tacttgcaac ttgcaaagtc aactttcttt
    12061 ttaacccttg ataactcact tctcttccaa tactcaatcg taaaacttta tttttcagct
    12121 caatatattg aaaacctagc aaaacaatga tgattggaat aataaatgat tgatagaaac
    12181 ctagattgaa ctggagaata cgaaaatcta atgctgattt taataagtca tttttaattg
    12241 cttgtccatc gaatttagct agatcgggcg catgaatatc aaaaaagaaa taagtcatca
    12301 aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag caagacataa acaaatttat
    12361 gccttgccaa agttaagaga ggaatcttca taagccacct cctacaaata gaaagtaata
    12421 taatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaagttg ctcaaagcac
    12481 tgctttgagg ttgtagataa gactgacgaa gtcagttaca tatataatcc aaggcgacgt
    12541 tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat gccttacgcc tttagacttc
    12601 cctagttccc gtctcaagtc aagcattttt ttgaaacaga tatagtctaa ccagtcacta
    12661 gcaaaagcga taagtagtaa taatagccaa ataccccata acttgatatc tgtcaaattt
    12721 ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc aagcaaggct aaaaagagaa
    12781 tagagggtga tgtaaatcca gtaaaaatag taaaaaattg ggaaaaattt actttctcta
    12841 ttatccttgt caatccagct gaaaaagtaa aaacagggta ataagattat cattttaaac
    12901 aagtgttcca tcacaagcct ccttttttaa attgttttct ttagtttcgt tctattaaat
    12961 attattatca atataaacct tggaatagcg tgtaataaat gattttagag gtaccataag
    13021 ccacctccta caaatagaaa ccgatataaa tcaatgcctt ccacccttag acttccctag
    13081 ttcctgtctc aagcgaaaca tttctttgaa acaggaataa gttaaccaat tcataccaat
    13141 agctagcaga ataaaaagaa accaaatgcc ccataacttg atatctgtca catttctcaa
    13201 gacggtattg aaaaacagaa ctgaaacaac tgtccaagca aggctaaaaa gagaatagaa
    13261 ggggatgtaa aaccagtaaa aataataaaa aattggaaaa aacttactat ttctgttggc
    13321 cttttcaatc cagttatcaa aataaaagta cggtgctaaa agtaagaatt taaacaaatg
    13381 ttccatcacc gacatcaccc tccttctttt gatagcgttt tctattattt tattatatca
    13441 aaaaaatccg gaactgtcat tccagattct acttttttat ttgcgttttc ttgcgatgag
    13501 atgaatcggt gttccctcaa aaacaaaggc cttgcggatt tgattttcca agaaacgcag
    13561 gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg acaaaggttg gtggtttggt
    13621 tgccacttgg gtcgcataga aaatcttgag acgttttcct ttgtctgtcg gtgttgggtt
    13681 gatggcaatg gcatccatga tgacatcgtt caagacagct gatggaatac gtgtattttg
    13741 actttcgctg atttgcttaa tcatctcagg aagtttgtgg agacgttgct tggttaaagc
    13801 tgatacaaag ataatcggtg cgtaaggcag gtattggaac tgctcacgga tatcttcttc
    13861 ccagtttttc atagtgtggt tatctttttc aagcgtatcc cacttgttga ccacgataat
    13921 catcccttta ccagcttcat gggcaaatcc tgcgatacgc ttgtcgtact cacgaatgcc
    13981 ttcttccgca ttgatgacca tcaagaccac atctgaacgg tcaatagcac gcatggcacg
    14041 cataacagag tatttctcag tattttcata aaccttacca gacttacgca taccagccgt
    14101 atcaatcatg gtaaactctt gaccatctgt atctgtaaag tgggtatcaa tggcatcacg
    14161 agttgttcca gcaacaggac tagcaataac acggtcttcg cccaagatag cattgatcaa
    14221 gcttgatttt ccaacgtttg gacgaccaat caggctaaac ttaatgacat ctggattttc
    14281 ttcttcatat tcatttggaa ggttttccac aatcgcatct agtacatccc ctgtaccgat
    14341 accatggaca gatgagatag gcagtggttc acccaaaccg agggcataga aatcatagat
    14401 atcatttcgc atctcagggt tgtccacctt gttaactgcg aggataactg gtttgtgggt
    14461 cttataaagc ttacgggcta cgtattcgtc tgcatcggta attccttcct taccggacac
    14521 gacaaagacg ataacatctg cttcttccat ggcaatttct gcctggtgct tgatttgttc
    14581 catgaaagga gcatcgacat catcaattcc tcctgtatca atcatgctaa aagaacgatt
    14641 gagccactca cccgttgcat aaatacggtc acgtgtcact ccttcgacat cttctacaat
    14701 ggagattcgc tcaccagcga tccgattaaa tagggttgat ttcccaacat tgggacgtcc
    14761 tacaatggca atagttggta gggccataat ttctcacttt ctacaataat ttcttctgtt
    14821 caagattttt tctagttgag cttggttcag cttgaccaaa ctgttctgct aggcgctgac
    14881 tccagcttgt ggtcgcacgc gccccagcat agtcagcctg aacacggtca taagcttgga
    14941 ttgcctcagt tgactgttct tggtattctt cctcaaagac aacattctct agtggcagtc
    15001 tcggtttcat atcatgatgt tgatttggca cacccagtgc catcccaaag acagaatagg
    15061 tgtagtcagg caggttaaag agctctgcca cttcttcaga cttgtatcga accaaaccga
    15121 taatcacacc accatagccc aagctttcag ctgccaacaa ggcgttttgt ccagcaagag
    15181 ctgcatcgac cgaactaatc aagagacctt ccacaccttg gggttggaag gtgtcggtat
    15241 gaagtcgggc tcccttttct gctcggttca aatctccgac aaagagaagg aaaacagcag
    15301 actggcgaat ggcttcttga ggtaccaatt catacaaggc atctttcttc tcttgacttc
    15361 gtaccacaat cacagagtag gattggaaat tcttccaaga tgatgccatc tgggctgctg
    15421 tcaaaatctc atttaagtct acttggggaa tttcttgctc tttaaacctg cgcactgaag
    15481 tatgagcctt catcaattta atggtttctg tcatcgacgg tttactcctt ctaaacgagt
    15541 ctcctcagcc aaataacgga tgcgttccat gacccgtctg gcttcccagg tttcgtcatt
    15601 tccatgtttc actttcgcaa aatgcttctc caaatcttca aagttgaagt tggatgtgaa
    15661 aaaggtcggt aaattttcct gcatccgata ttggagaatg acctgcagga tttcgtcacg
    15721 cacccaaacg gttgattgct cggcgccaat atcatctaaa atcaggacct cagacagctt
    15781 aatctcatcc accaaggtct taacattgcc atcactgata gcatttttga catcaatgac
    15841 aaagctagga tagtggagga gagttgatga aacaccacgt ttttctgata aatcatgagc
    15901 taaggccgcc accatgaaac ttttacccac accaaagtct ccatataagt aaagaccttt
    15961 tcgaatagct ggatattgct ccacgaaggc tagtagcttt tcaaaaactg gtaagcgccc
    16021 caaatcatcc aagtcaactt gagccaaact agctttcttg agactggctg gtagattgat
    16081 taacttgaga cggttcttaa tagccgcttc tttttcagcc gcgattagct caggagtttc
    16141 ttcatatgaa acatctgcat agccatgatt cttaaccaaa atcggcttgt agcctttggc
    16201 aatataatcc gtatccccac ggagaaactt gtcacgctcg gtgatgtact gattaaactt
    16261 ggagatactg cgatttaatt cctctggagt taaggattct tgctggataa aggccgcaac
    16321 atcagggtcc ttcatgattt tctggaccaa atcttgataa taaaaacggc tgggttgacg
    16381 tttgagtacg tctccgacac tttccatcta atctcctcct ttttctaatc gagctaatag
    16441 ttcttgcttc ttacgttcta gttccagacg agtttcctcg ctggtttcat tcttatattc
    16501 aggattactc catttaggaa cattggtttt ttctggggca gtctgattct gtttttgtgt
    16561 ttttgctttc tgccctcgat cacgaattcg taaaacggcc tcttctgccg aatgaatctt
    16621 ttgataggca tagtcattgg ctaccttcat ggcatatttc tcattgatat ttgccgaatc
    16681 caccttatta aaggtcaata agagaataat attgatgact tcgtccagta agcccaagcc
    16741 agccatctgt tgcaagagtt ctctttctgt ttgggtaatg gttcccttgc gtgtttgctt
    16801 gatttctgct aagaactgca gggcagtttt acttttagct tctttgataa tggtcgcttc
    16861 cttaagacta aagtcagagg aaactggttt ttgagcaatt ttttcacgca tgcgtttggt
    16921 tgaaataacc tgggaaacag ctgttgactt ggccaattga taggtttcaa accaagtcca
    16981 tttcttctcc tcggcaatag caaagaggtt taagacatcg gactgctcat ccgcaaaacg
    17041 aagtccatct cgagccatca gctggcgaaa atgttccaag tcaaaatcat tggccacttt
    17101 cttcttgaga ccaaggtctt cttgactgcc tagttctgcc aattctggaa agacttgatt
    17161 gagtgagaca ggtatttctt caccatcagc actttcaact ttcaaatcct ccacagctac
    17221 atcgccaatc tttttctcta agagtctgcg ataaacagga tgccccaaga agtcttgact
    17281 agatagagga gcatggaggg ctagctgata aacatcaccc ttttgataga gggtcaagag
    17341 attaaaagca gataagattt tcaatgattt tatcagtcta tccatcccaa agttgagatg
    17401 gttgagaatg cttgaaaaaa gatattcctt tctaccatta tcccaaaaac tgattgtata
    17461 aagataaagg ctcagtgcct cctgaccgat aatcgggagg tagcactgta ccagagatga
    17521 ggtatcttgc gacacccgat tattctttag ataagaaaaa cggtcaattg gcttcattta
    17581 tctttccttt ttctttttag aggactgggt gatttgttgg agcaagctct ctaactcact
    17641 gacatcctta aaactacgat agacactagc aaaacgtaca taggtaatct cgtccaattc
    17701 agccaactcc tccatgacga gtgaaccaat gtcctcactt tgaatttcat tttcatttcg
    17761 accacggagt ttctgttcga tacgattgac taccatgttg atttcatcac ttgacacagg
    17821 acgtttctgg gctgagcgga taatcccatt aaagatttta tctctggaga attgttcccg
    17881 tgtgccatct tttttaacaa ccactaaggt tctttcttct actcgttcgt aggttgtaaa
    17941 acggtgttgg cattcgtcgc actcacgtct tctacgaatg gtgttccctt cttctgcttg
    18001 gcgactatcg ataacacttg acttggtagc cccacatttt ggacaacgca tcctttccct
    18061 ccttatcgtt ttcttttcat tataccattt tttaagcgat tcccaaaaca attcttcttt
    18121 ttgcttgaca agttttttgt tttgttgtat tatttaatta agacaacaag gtaaaagaaa
    18181 ggagactaag atgtcctgga catttgacaa caaaaaaccc atctatttac agattatgga
    18241 gaaaatcaag cttcagattg tttcccatac actggaaccc aatcaacaac ttccaaccgt
    18301 gagggagcta gctagcgagg ctggtgtcaa tcccaatacc atccaaagag ccttatcaga
    18361 ccttgaacga gaaggatttg tctacagcaa gcgaacaact ggacgatttg tgactaagga
    18421 taaggagcta atcgcccagt cacgcaaaca attatcagaa gaagaattgg aacacttcgt
    18481 ttcctccatg acccattttg gctatgaaaa agaagaacta ccaggcgtag tcagtgatta
    18541 tattaaagga gtttaagcct atgtcattac tagcatttga aaatgtatcc aaatcatatg
    18601 gagcaacacc agcccttgaa aatgtttctc ttgacattcc agctggaaaa attgtcggcc
    18661 ttcttgggcc aaacggctca ggaaaaacaa ccctgattaa actaattaat ggcctcttac
    18721 aaccagatca aggacgtgtc ctcatcaacg acatggaccc aagcccagca accaaggccg
    18781 ttgtagctta tttgcctgat acgacctatc tcaatgagca aatgaaggtc aaagaagccc
    18841 taacctactt caagaccttc tataaagatt tcaatcttga acgcgctcat catctacttg
    18901 cagacctggg cattgatgaa aatagtcgtc tcaagaaact atcaaaagga aacaaagaaa
    18961 aggttcaact gattttggtt atgagccgtg atgctcgtct ctatgttttg gatgaaccca
    19021 ttggtggggt ggatccagca gcccgtgctt atatcctcaa taccattatc aacaactact
    19081 caccaacttc taccgttttg atttctaccc acttgatttc tgatatcgag ccaatcttgg
    19141 atgaaattgt cttcctaaaa gacggaaaag tcgtccgtca aggaaatgta gatgatattc
    19201 gctacgagtc aggtgaatcc attgaccaac tcttccgtca ggaatttaag gcctaagcaa
    19261 aggagattat ttatgttttg gaatttagtt cactacgaat ttaaaaatgt taacaagtgg
    19321 tatttagccc tctacgcagc cgtgctagtc ctttctgccc tcatcggaat acagacacaa
    19381 ggctttaaaa atctacctta ccaagaaagt caggctacta tgctactttt tctagctaca
    19441 gtctttggtg gcttgatgct tacacttgcg atttcaacca ttttcttgat tattaaacgc
    19501 ttcaaaggta gtgtctacga ccgacaaggc tatctgactt tgaccttgcc agtttctgaa
    19561 caccatatca tcacagccaa actaatcggt gcctttatct ggtcattgat tagcaccgct
    19621 gtattggctc taagtgctgt tattattctg gctttaacag ctccagaatg gattcctctt
    19681 tcttatgtga ttacatttgt agaaacacat ctccctcaga tctttcttac aggtatatcc
    19741 ttcctactaa ataccatttc aggaatcctc tgcatctacc tggctatttc cattggacag
    19801 cttttcaatg aataccgtac agcactcgct gttgcagcct acattggtat ccaaatcgtc
    19861 attggattta ttgaactttt cttcaatctt agttctaatt tctatgtcaa ttcactggta
    19921 ggactcaatg accatttcta tatgggagca ggtatagcca ttgttaaaga actcatattc
    19981 atagctatct tttatctcgg aacctactac atcttgagaa ataaggttaa tttgctttaa
    20041 ataattttta cctagatatg taacatactc atagaacaaa agagaccagg caaaaagtct
    20101 ttaaaattag aaaacgcata gtatcaagtg ttaaaaatcc ttgatattat gcgttttttg
    20161 tgagttgact tatttccttt cactatatcg caaaatgaaa taagaacgga acgatgggat
    20221 tttggaattc aaatcaattt gtaagaatgt tttagaagta atattatcct attccagatt
    20281 cagttcacta tacaattgag ttttcaagca acttgtttac ataatgtgta cataattagg
    20341 ttcgtgattc cacccttttc acctttaaaa acctcgcttt cgcaaggctc ttctatttat
    20401 aagataaggc acgtttaaag gttttccaaa tccctaaatc atccgtttga agaacgagac
    20461 tagcatacat gcgtccgata aatcctgttg ctaccaccgc aaaaatcact gtaatagcaa
    20521 gtgaaatcca tgcttccgct ccccccgcat agccattaat cgttcgaaac ggcataaaga
    20581 aggtcgaaat aaagggaata taagaaccaa tcttcaagag gagattgtca ccagctgcac
    20641 ctagagctgt cactccaaaa aaaccaccca taatcaaaat catcaaaggc gacaaggctt
    20701 tccctgagtc ctcaggacga gaaaccatag atcctaggaa ggctgccaag actacataca
    20761 tgaaaagact gatcaaaata aagagcaggg tattcagtga gatagcatct cccaagtgat
    20821 ccaaaatacc agactgagcc aagaatggca aatctttaaa gagcaaaacg gcagccagac
    20881 cacctacaac atagatccca atatgcgtta aaatcactag aaacagagcc atcatccgcg
    20941 catagaaata gtgacttgcc cttatgctag aaaaaacgac ttccataatt ttggtgcctt
    21001 tttcactggc aacttcctga gctgttacac ccgcataggt aatcagaatc atataaagaa
    21061 agaatcctaa ggcacctgct gcaattgttt gaataaactt tttattttcc ttggcttcat
    21121 caatcttttc tgtgaattga attgtctgcg ctaagcgttt ttcctgctct tgagacaagg
    21181 aagcagttga acgattaagc tgattttgca gttcattgag tgtacctgta acctcaaatt
    21241 taattccatt ttcaagcgat gtttcgccat gataaactgc ctttagaaca ctatcttctt
    21301 gatcaatggt caaataacct tttaattttt cttctttaat tgcttctttg gcacttgctt
    21361 cgtctttata gtcgaagtta acaccattta cattcttcag tccttctgct acagatggca
    21421 ctgttgtcac tacttccact ttattatttt tagccataga agaaccttgg agatgcccaa
    21481 ttcctacaga gattcctaaa aagaggaacg gcgaaatcac cataaagaag aaactccatg
    21541 actcgacatg tcgaagatag gtttccttga ttacaaccca catatttctc atacttccac
    21601 tcctgattct agtttaaaga tttcatcgat agttggcgct tgttggtcaa atgttgcgat
    21661 atattgacct tgagtcaaga ttgggaagag ttcccttcca gcgctctcat cctccaaaat
    21721 caatttccaa ctgccttgtt tggtcaagct cacctgtttg acatgaggaa gattttccaa
    21781 ttcttccttg cttcgttcac ttgaaacaaa gagacgcgtt ttcccgtatt gattgcggac
    21841 atcctgaact ggtccgtgca agaccacacg gccatctcgg atcatcagaa tatcgtcaca
    21901 aagttcctca acattggtca tgacatggtc agaaaagata atggttgctc cgcgctcttt
    21961 ttcctgaaaa atgacttgtt tgagcaattc tgtattaact gggtccaatc cactaaaagg
    22021 ctcatccaag ataatcaggt ctggttcatg aatcagagta ataatgagct gaatcttctg
    22081 ctgatttcct tttgacagac tcttgatttt atctgtcagc tttcctttca cttccaacct
    22141 cttcatccat tgagggagtt tttctttgac ttctttggca tccatgcctt ttagagtcgc
    22201 caagtagcga acttgttcaa gaactgtcaa tttaggcatg agactgcgtt cttcaggcag
    22261 ataaccaatc cgagcatagg tctcctgacg aatatcctga ccatctagac cgatttctcc
    22321 ctgatattct aggaatttca aaatactatg gaaaatcgtt gtttttccag caccattttt
    22381 tccgactagt cccaaaatac gacctggtcg cgcttgaaag tcaataccaa acaaaacttg
    22441 cttggagcca aaacttttct ctagacttct tacttctagc atctttcacc tccgaaattt
    22501 cttgcactca ttatactcct ttttgatagc ctttacaatg ttttttgtcc atttttagaa
    22561 gactattgct gtgtaaaata tggcctggag cacttttata ctcaatgaaa agcaaagagc
    22621 aaactagaaa gctagccgta ggctgctcaa agtacagctt tgaggttgca gataaaactg
    22681 acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaact
    22741 atatctacgg caaggcgaag ctgacgtggt ttgaagagat tttcgaagag tattagtgat
    22801 aaatccatta tacagtagca aacttaattt ataccttccg ctcctcaact gtctattttt
    22861 aatcctgaat tgttatttga gtaactcctt tttcctcata aagttttctt cctctaaaac
    22921 ttctggaaaa aagcgaatag tttcagataa catttttata aggaacaagt tcatctgtca
    22981 tttcaagaag gagtaatcct ttatctacta atggacggaa cggaattcaa ccgcttgtcc
    23041 gatatgtttt ctaaggatta tatagtaaaa tgaaataaga acaggacaaa ttgatcagga
    23101 cagtcaaatt gatttctaac aatgttttag aagtagatgt atactattct agtttcaatc
    23161 tgctatatct attatgcaca ccactatagg atctaataaa aatcacaaca agttcattca
    23221 tagatggtta cctcagggaa ctaagaaaac gactacaaag gaagtcgcat tcatcgaaaa
    23281 gtggattaac aactatccta aaaaatgctt gaactacaag tcccccagag aagacttctg
    23341 gatgactaac ttgaacttga aatttagcaa taattaattc accatctaac tatatttagt
    23401 aattatttca gaactgatta atattaaaat taactaacaa ttcaaaggat tcatactagc
    23461 cataaattac gtccatcaga gagagactct tactactttt agattttagt ctttctagct
    23521 tcagaataca tctaaacttt agggaaaatg actattcgaa agcgcgaatg cctcaaaatt
    23581 atctcagata agctattcga aacttagaat gcttttaaat ttatggaatt gcgattattc
    23641 gaaacctaga atgcatataa cctttagttg acagacctat tctaagtctc gaagggctat
    23701 ttactttcta ttccttatca aaaaagactc attccccctt tctcctccaa aatatggtat
    23761 agtagaaata tactatctat gaggagttta catgtcacag gataaacaaa tgaaagctgt
    23821 ttctcccctt ctgcagcgag ttatcaatat ctcatcgatt gtcggtgggg ttgggagttt
    23881 gattttctgt atttgggctt atcaggctgg gattttacaa tccaaggaaa ccctctctgc
    23941 ctttatccag caggcaggca tctggggtcc acctctcttt atctttttac agattttaca
    24001 gactgtcgtc cctatcattc caggggcctt gacctcggtg gctggggtct ttatctacgg
    24061 gcacatcatc gggactatct acaactatat cggcatcgtg attggctgtg ccattatctt
    24121 ttatctagtg cgcctatacg gagctgcctt tgtccagtct gtcgtcagca agcgcaccta
    24181 cgacaagtac atcggctggc tagataaggg caatcgtttt gaccgcttct ttatttttat
    24241 gatgatttgg cccattagcc cagctgactt tctctgtatg ctggctgccc tgaccaagat
    24301 gagtttcaag cgctacatga ccatcatcat tctgaccaaa ccctttaccc tcgtggttta
    24361 tacctacggt ctgacctata ttattgactt tttctggcaa atgctttgac acgtaaaaaa
    24421 tccgtttggt ttcccaagcg gattttgtgc tttattttga aacttctttt gcaagaacaa
    24481 agttcccaag tgtggcagaa ccatttcctg cgactgctgg cgtcacgata tagtcacgca
    24541 catctggtac tggtaggtaa ccattaagaa gagatgtaaa tttctcacgg acacggtcca
    24601 gcatatgttg ttgagccatg acccctccac caaagacaat cacgtctggg cggaaagtca
    24661 ctgtcgcatt aaccgcagct tgagcgatat agtaggcttg aacatcccaa acagggttgt
    24721 tgagttcaat agtttcccca cgtacacctg tacgagcttc caaacttgga ccagctgcat
    24781 aaccttctag acatccctta tggaaaggac aaacaccctt aaactctttt tcaatatcca
    24841 ttgggtgtct agcaacataa taatgaccca tttcagggtg acccacacca ccgataaact
    24901 caccacgttg gatgacgcct gcaccgatac ctgtaccgat tgtgtagtaa accaagtttt
    24961 cgatacgacc accagcattg ttacgggcaa ccatttcacc gtaagcagag ctgtttacgt
    25021 ctgttgtgaa gtacattggc acgtttaggg cgcgacgaag ggcaccaagc aagtccacat
    25081 ttgcccagtt tggttttgga gtcgtcgtga taaagccata agtttttgag tttttgtcaa
    25141 tatcaatcgg cccaaatgaa ccaactgcaa gaccagcaag gttatcgaat tttgagaaga
    25201 actcaatggt tttatcgatt gtttcgattg gagttgttgt tggaaattgt gttttttcta
    25261 caacgttaaa gttttcatca ccgacagcac agacaaactt tgtaccgccc gcttccaagc
    25321 ttccatataa ttttgtcatg ataaacctct tgtttttatt ttctttatta tagcatactt
    25381 cgaaagtcta aatgtctcta ttttttagat tttcctctgt aaatcttact atctaataaa
    25441 aacgaacaaa catgtcattt gttcgttttc acattagaga ggattgatta gattttcact
    25501 tcgatcacag cattcccctt cgcaactgaa cctgttgcga ctggagctac tgaagcgtag
    25561 tcagctgtat ttgtaacgat aaccattgtt gtatcatcaa gtccagctgc agcgattttg
    25621 tttgagtcaa atgttccaag aacatcgcca gctttcacct tattaccttg agcaactttt
    25681 gcttcaaaac cgtcaccgtt catagataca gtgtcaatac caacgtgaat caaaacttca
    25741 gcaccatttc ttgttttcaa accaaaagcg tgccctgttg gaaaggcaat tgaaacttca
    25801 gcatcagctg gtgcatagac cacgccttgg cttggtttca cagcgatacc ttgtcccata
    25861 gctccacttg agaagactgg gtcattgaca tcagcaagag cgacaacatc accaacgata
    25921 ggagttacaa gtgtttcatt ttgaagagta tcagtctctt ccactactgg tgcttctact
    25981 gtaggttctg taactgtttc tgcggttgct gtggcagctt catcagcaaa gacactagct
    26041 gcttttgttt tcccgtagaa ataagtgaaa gcaaaggcgg caacaaagga cataatttcc
    26101 gcaattatat acatagggat tgaaccagcc ttaatagaaa ggaatccaat aaatccagcc
    26161 gctcccaatg aaactgcaat aacgtgagtt aaacctgcta caaaggcacc aattgctgaa
    26221 ccagcaaggg cgcagaagaa tgggaatttg tatttcaagt ttaccccaaa gagagcaggt
    26281 tctgtaatac caaggaaggc agaaacagca gccgaactgg acaatccttt tgttttagca
    26341 ttttttgtca agaagtagac tgcaagagta gccgcacctt gtgctacgtt tgccattgaa
    26401 gcaacaacaa agatgtagtc tccaaatcca gtaccgttat tattgtatgc agacaacaat
    26461 tgtgtttcga ttgctgggaa tgattggtga agacccgtca taacgattaa tgagtaagtt
    26521 ccaccaaata gccccatacc aaaggcacct gttgtgttgt acaaccatac aatcgcattt
    26581 gtaatcgcat cagacacaac caacataaca ggaccgataa ctgtaaaggt aaggaatcct
    26641 gtaatcatca ctgataaaag cggtgtaaaa gtgaagtcaa ctgcagatgg caatttcttg
    26701 tggaagaatt tttctaaatt agctaacaac cagactgcaa caaggactgg aataacctga
    26761 taagcatagt ttgtttgtgt aacatggaaa cctaagatgt cccagaaggc ttctttacca
    26821 cccaaatctg gagtggtcat aatcataccg attgccgcac caaggaattg gtttgctcca
    26881 aagcgcttgg ctgctgaaat accaatcaaa acagggagga acataaatgg agcagcagac
    26941 atcaattgaa tcatagctga gaagcctttg atagcaggat acatatcttc aattgattga
    27001 ggtccaaaca aatctggtga tgtcaagaag ttccgtaaag ccatcaagag accacctgca
    27061 actaaggcag ggataatagg aacaaaaatg tctgacaaaa gtttaatcaa gtccatcaat
    27121 ggattgaact ttttgtcttt attagcaatc tctttcaaat catctgtcga aacttctttc
    27181 aaaccagttt tcttaataat ttccgcatat acgaagttaa catcaccagg accaatgata
    27241 atttgatatt gtccgttagt gctaaaagtc cccttgacat ccgcattatt atccagagct
    27301 gcttgattca cttttgcttc gtctttcaat accaagcgaa gacgtgtcgc acagtgagct
    27361 gcagctacaa gattatcctt accgacagcc tcaatgacct cggcagcaac tttactataa
    27421 tccatagcaa aaatctcctt atataacatt ttgttcttgt ttgaaagcga ttttattcgc
    27481 ccttacgact attattttat catgttttaa aaatatgtca agcgttttgc agaaaaaata
    27541 ttatatctac ttagtgggca agctttagat tgattgtttt tgactgtttc atcaggaatt
    27601 tcttgaaaaa taagtttgaa accttggtta aaaagtcttt tatttcatta tctttcacat
    27661 tttcgtaaaa atttgattga tttcctgtat ttattttatg ataatcgttt gacagttttt
    27721 tctctttttt aacataaagg gcttgcattt tttatcgaaa acagttacta ttaaaagtga
    27781 taagattttt ggaggaatga atggaatgga caactgagcg tcgttacaga ctttatcaag
    27841 attggacgca agaagaaatt caacatataa aggaaaatat ggcacaatct ccatggcata
    27901 ctcattacca tgttgagcca aaaacaggac ttctcaacga cccaaatggc ttttcttact
    27961 ttgatggcaa gtggatcctc ttttaccaga attttccttt tggtgcagcc cacggtttaa
    28021 aatcttgggc acagctagaa agtgatgatt tgattcactt tagagaaact ggagtcaaag
    28081 ttttgccgga tactccatta gatagccacg gtgcctactc tggttctgcc atgcaatttg
    28141 gcgataactt attcctattt tatacaggaa atgttcgcga tgaaaactgg atccgtcacc
    28201 cataccaaat cggtgctttg atggacaagg agggtaagat tacaaagatt gacaagatct
    28261 tgattgacca gccagcagac tctactgacc acttccgcga tccacaaatt tttaacttta
    28321 aaggtcaata ctatgctgtc gtcggtggac agaacttgga gaaaaaaggc ttcgtccgtc
    28381 tctacaaggc tgtcaataac gactacacaa actggcaagc agttggcgac cttgactttg
    28441 ctaacgaccg tactgcctac atgatggaat gtcctaatct ggtctttgta gaggaacagc
    28501 ctgtccttct ctactgtcca caaggattgg ataagaaagt tctagactac gataatatct
    28561 ttccaaatat gtataagatt ggggcttcct ttgaccctaa aaatgccaaa atggtagatg
    28621 tgtctcaact tcaaaacatg gattacggtt tcgaagccta tgcaactcaa gccttcaacg
    28681 ctcctgatgg gcgtgctcta gcagttagct ggcttggttt gccagatgtt tcttacccat
    28741 ctgactgttt tgatcaccaa ggaaccttct ctttggtcaa ggaactcact atcaaagacg
    28801 acaagctcta ccagtatcca gtcgctgcta ttaaggacct tcgtgcttct gaagaagcct
    28861 tctcaaaccg ttcccaaacc aagaacactt acgaacttga actcaacttg gaagctaata
    28921 gccagagcga gattgtctta cttgctgata aagaaggtaa gggactttca atcaactttg
    28981 accttgtaaa cggtcaagtg acagtggatc gtagccaggc tggagaacag tatgcccaag
    29041 aatttgggac aactcgttct tgccctatcg agaatcaggc tactactgct acaatcttca
    29101 tcgataactc tgtctttgaa attttcatca ataaaggaga aaaagtattt tctggtcgtg
    29161 tcttcccaca tgcggaccaa aatggtatcc tgatcaaatc tggaaaccca actggaactt
    29221 actatgaatt agattatggt cgcaaaacta actgatgtcg ccaaacttgc aggcgtcagt
    29281 cctactaccg tttctcgggt tatcaataaa aaagggtatc tatctgagaa aaccatccaa
    29341 aaagtcaatg aagccatgag agaattgggc tataaaccca acaacctggc tcgtagtctg
    29401 caaggaaaat cagctaagtt aatcggcttg attttcccca atatttccaa tgttttctat
    29461 gcagaattga ttgataaatt ggaacaccaa ctcttcaaaa atggttacaa gaccatcatc
    29521 tgcaacagtg aacatgattc tgagaaggaa cgcgaataca tcgaaatgtt ggaagccaat
    29581 caggtagacg gcatcatttc tggtagtcac aacctaggaa tcgaagacta caatcgtgtg
    29641 acagcgccga ttatttcctt tgaccgaaac ctatcgccag acatccctgt tgtctcctct
    29701 gacaactatg ctggtggggt tcttgctgcc caaaccttgg tcaagacagg tgcccagtct
    29761 atcatcatga ttacagggaa tgacaattcc aattcgccaa ccggactgcg ccacgctggt
    29821 tttgcatccg tactcccaaa agctcctatt atcaatgttt ccagtgactt ttctcccgtc
    29881 agaaaagaaa tggaaatcaa gaatatcttg acccgggaaa aaccagatgc catttttgct
    29941 tcggatgatt tgacagctat tctggtcatt aaaatcgctc aagaattggg catttctgtc
    30001 ccaaaagagc tcaaggtcat cggctatgat gggacctact ttatcgaaaa ttactaccct
    30061 caattggcta ctatcaagca acctttggaa gagattgctt gtctcactat tgatcttctc
    30121 ttgcaaaaga ttgaaggcaa ggaagtcgcc acaactggtt acttcttacc agttacgcta
    30181 ttaccaggaa aaagtattta aacacaagaa aactcagacc gattcgtctg agtttttatg
    30241 atcttaaatt ttcgagatag cgctgggctg tctctaggtt aaaggtttta tctgagatga
    30301 ggcgctctac taggggagca acttcagatt cactagcccc agctaggaga gctagggatt
    30361 tggcctgtag tttcatgtgg ccttgctgga tgcccgtact taccaaggct ttgagggctg
    30421 caaaattttg agcaagaccg atggacacga taatctgggc taattctctg gcagaaggat
    30481 ttcctagtag atcatgactg agagctacac gtgggttgag gccgatagag ccacccttag
    30541 tcgctacagg catgggcagg gtcatctcac cgaccaattc ttctctttca aggtccagcg
    30601 tccagcagct aagaccttga tagcgtccat ctcgactggc aaaggcatgg gccccagctt
    30661 cgatggcacg ccagtcatta ccagtggcaa tcaaaatcgc atcaatacca ttaaaaattc
    30721 ctttattatg agtagcagct cggtaaggat cagcctgcgc aaactgacta gccaacgcaa
    30781 ttttctccgc aatctctcgt ccttgatcct tttggcggct caagtagcga aaggcgatgc
    30841 gacagcttgc agtcaccaga gaatcagtcg cgtagttgga caggattccc atgagactct
    30901 gtccctgact gagttcttct aagactggtt tcaaggcttc cagcatggtg ttgagcatat
    30961 tggcacccat ggcttcctgg gtatcgacat gaatataaac aacgagaaag tctggttcgc
    31021 cttttatctg ctcgacatgc agatcacgcg ccccacctcc acgtttaacg atagaaggat
    31081 aggcttgatt ggcaagctcc aagagctccg ctttcttgct ggcaatcttc tcttgcgcta
    31141 gtttaggatt agcaacttga taaagggcta cctgcccaat catctgtcgc tgatggactt
    31201 gtgcagtaaa accacctgca cgcttgatga ttttgctggc atagctggcc gccgcaacca
    31261 cagagggttc ttctgtcacg tagggaacgg tgtattcctg accgttgaca agtacctctg
    31321 gaaccagtga ataaggcaga gaaaaagttc ccactacatt ctcactcagc tggtctgcca
    31381 cagtcacgct catctgttca tccttctcca gactagcttg tctctcagga ctaaggagcg
    31441 cctgagcttt taacagctcg aggcgctctt ggtatgattt tttagaaaat ccattccaac
    31501 ttatcttcat tatttttcaa ccttgctata acggcgttgg tggtcgagaa tttcaaccaa
    31561 ggcaaaatct tgattttcat agccagcaaa ctgggcagag tttgtttcat ccaagtttac
    31621 ttcctcaaaa aagacctttt catagtctgc aacggatagg gcagttcgtt ggttgagctt
    31681 gttcaaacgg tctttattca aataagcttc atatccttca accaattcac cactgaagaa
    31741 ctcagccaca gctccacttc cgtaactata aagggcgatt ttatccccag ctttcaagct
    31801 atctgtattt tccaagagag acaaaagtcc aaggaaaagt gaacctgtgt agatattccc
    31861 caccttttga ctgtagagaa tagactggtc aaaatgcttt tgtaagaggt cttttttctc
    31921 ttgaggcagg ctcttatcca tgattttttt caagcctttt agcgctaatt taggataagg
    31981 caagtggaaa caaacagccg caaaatcatc caaagtaagc tggtagcgtt tttgatattc
    32041 aagccaagtc gttttcaaac tatccaagta ttgttgggta gaatagacac catttacata
    32101 aggagttgtc gagtaatttg gtcgccagaa atccatgatg tcacgggtct gagctacatt
    32161 gtcattatta aaggccatca tgcgtggatt ttgtgtaatc aacatagcta cacttccagc
    32221 accttgagtt ggttctcccg gagtttcaat accatatttg gcaatatcac tggcaatgac
    32281 caataccttg gactccggag aattttccac atgcaatttg gcataatgga gggcagctgt
    32341 cgccccatag caggcttctt taatctcgaa actacgagca aagggctgga tgcccagcaa
    32401 gccatgcaca aagacggccg cagccttact ctggtcaatt cctgactcgg tagccacaat
    32461 gaccatgtca acttcttgtc tttcttgctc agttaaaata gagtcactag cactggccgc
    32521 caaggtcacg atgtcctcag ttaggggcgc aatactcaat tccttgagta agagtccttt
    32581 acttaatttt tcagggtcaa ttcccctcgc ttctgctaag tcttgtaatt tcaagacata
    32641 ttgactggtc gcaaaaccaa tcttatcaat accgattgtc atatttacct ctgttttatc
    32701 attcatgtaa aaaatcgttc tatactattt tatcacaaat ggcagtaaaa gagagaaaaa
    32761 agacttgatt caccaaatca agcctcttat tggtcatcat tttaaagaat gattagttgc
    32821 tagagagttc accgatataa gtagctttat aagctccatt cacagttatc agctcctgga
    32881 ggatcaaatt tcctgagtaa atccttccca tctcatctac aaatttttga taaaactgac
    32941 tggtcggaat ttctctgaca tccttatcaa atgtcttgtc aagtgtttta ctaaccttct
    33001 cagcaatcaa ttgatgctct tgccatccac tttgaaactc tgagcccgaa ctagaaacca
    33061 tgactgggat aaacaacaag gtcagtagat ttacagacaa taaggaaagt agtagacttc
    33121 ctgcaaaact agaatcctag ttcatgattg ataatgccag caatcaaatt cattcgtaat
    33181 ccgaagcgtt tacgatgatt tcgataggtt gttgaaaaca ttttaaacgt ttttactttg
    33241 gcaaagatgt tctcaacctt gcttctctcc ttagatagcg catggttata ggctttatct
    33301 tcaactgtta gcggcttgag tttgctggat ttacgtggag tttgtgcttg aggatatatc
    33361 ttcatgagcc cttgataacc actgtcagcc aagattttac cagcttgtcc gatatttctg
    33421 cgactcattt tgaacaactt catatcatga caatagttca cagcgatatc caaagaaaca
    33481 attctccctt gacttgtgac aatcgcttga gccttcatag cgtggcattt tttttaccag
    33541 aatcattcgc taattgtttt ttttagggcg attgattttt acttccgtcg catcaatcat
    33601 taccgtgtct tcagaactga gaggagttct tgaaatcgta acaccacctt tgaacaagag
    33661 ttacttcaac ccattggctc cgacggagta agttgctttc gtggatacca aaatcagccg
    33721 caatttcttc ataagtgcgg tattctcgca catatagaaa gcgttgttaa tttatttatc
    33781 tcatttttca gaaaattctt ttatttctgt aaagtctacg atactcgatg tgtttttata
    33841 taatgataca gtctgagaat cactgttccg ctagccattc caatagagat taccaaagcc
    33901 aacatgacaa ccaaggtcgc acttgccagt gctttattat agtcccctgt cacaaaaaag
    33961 gcagttgttc ggtaggagag ataacctgga accagcggtg ccaaaatggc caagataaag
    34021 accacagcag gtgtcttata aagaatactt aaaatctggc tgacacaaga accaataatg
    34081 gctgcaatga aggtagctac aatgacattg gtcggttcct tgagcaagag atagattagc
    34141 cagacagtca tgcccaaaat ccctccaggt aagagcatag accgttgcac attgagtacg
    34201 attaaaaaag tgataatggc aagaaaactt gctactgctt gtaataaaaa ggttgttagt
    34261 gtcatattag ttcatcaata ccaaggcgac agaagttcct gcccctaaag cgagggtaat
    34321 gagcagggat tcaaacatct tactcatacc agagtttatg tggttggtca taatatcacg
    34381 gaccgcattg gtcaaggcaa tacctggtac aaacggcatg accgcaccag ctataatcaa
    34441 atctgccgtt gaaggaaaac ctgtgtagcg agcccaaaac tgggcaatta tcccaaagac
    34501 aaaggctcca gcaaaggctg tcacaaaggg aattcggata aatttttcca catagaggga
    34561 aaaggcaaaa ccaaataagg tcgccactcc tgccccaagt gcgtcgtaga tatttccgct
    34621 aaacataact gaaaagaaag gagcactaaa ggtcgcagcc agagttacct gcaacttagt
    34681 atagggaagg ggttgagctt gcaaggccgt caattgctta aaggctgttt ctaagtcaat
    34741 ctgcccccca actagctgac gagaaatctg gttcacatcg cagacttttt cgatgttata
    34801 agaagaggag gtcacgcgct tcatgcgcga aatattggta ttttcaatag agaaaaagat
    34861 agcggcaggc atggcaagga cattgcaatc cacaatcccc tgcgaatgcg cgattcgaat
    34921 catggtatct tctacacgat ggatttctga gccactttta aggagaatag tccccgctag
    34981 cataatcaca tcaatgacgg catttaattc ttttgattct tccatgcttt cctcctttta
    35041 tcaactccct ctattctatc acaaatctgg actcaaaaaa aaatctttgc catgaaatca
    35101 tgacaaagat tgattactca ttttgattat ccatctgctt ttaaggagta gctgaagttg
    35161 ttttaggttt gtagattgaa atcttgactc tagtcttatt taggtctacc ttttcacctg
    35221 ctctaggact ttgttcaaca accatgcctt ctacactacc tgcaggcgct gtcgtcactt
    35281 ctacaacttc tatattagct tccttaatcc caacaatttg aatcaaattg ttcttagtaa
    35341 actccaagct ggaaccaatg taactcggca tggcaacact tgtaactttt ttagctactg
    35401 tcaagacaat ttgagtaggt ttactcacat cataagtcgt tccggcacct ggactttgtt
    35461 tcataatcgt tcctggttcg ctttcgctgg actcttcttc ctctatctta atcaaattct
    35521 caggaacctt cttctgcttg agttctgaga ttacttctgt agagttccgt ccaatatagt
    35581 tccctaattg aatcgtcgta gcttttttag ctactgtcaa aacaatttga gttgccttac
    35641 tcaagtcata ggtcgtacct tctggtagac tttgcttcag gaccgttcca gcctcactct
    35701 cattcgactc ttcttcctca attttaatca aattatctgg aacttttttc tcttttaatt
    35761 ccgcgataac atcagaagat ttccggccga cataattact aatttggaag gattgtttgc
    35821 ctgatgagac aaccagattg attttcgttc cttcttttcg accagttcca gcgccaggat
    35881 ctgtacggat aatccgccct tcttccacct tttcactagc ctctgtcttc tcctcaccaa
    35941 tctcaaaatt ggcttttttg agcgttgcct tggcctctgc aactgtctga cctgccacat
    36001 ctggaatggc aatggttgca ggagttctgg atagtatcca aataagagaa gctgccacca
    36061 atacaaggct ggccaacaaa atcaggtaac gcatcttaaa tctatgtttt ttcggtgctt
    36121 gtggttggta agtttcctct gtcacagcct ggcttgggtt tttgattgat ttgtgttctg
    36181 tctgcgcttg aaccttagga atagatgtca aggtactctg agaaaccttc ggcaaggtct
    36241 tggtatctgc cttgctcgtt tcatcaaaga ttaacttact ttcatttcta cgattgtagg
    36301 acaagctact agacaagtcc acatacatct ctgaaaccga gcggtagcga ttggtcaact
    36361 ttttagcagt tgccttgata ataacatttt ctaaagcctg aggtacagat ggattttctg
    36421 caataacgga cggcaggggt ttctggaaat gctggagggc aatggtcacc gcgctatccc
    36481 cgtcataagg gatatggcct gtcaacatct catagaaaat aatccccatg gcatagatat
    36541 cactctgcac agtcgccttc gaaccacgcg cctgctctgg tgacaagtaa tgaactgagc
    36601 ccaacatcga gttagtctgg gtcagacttg tctctgcaaa ggctacagca atcccaaagt
    36661 ctgtgacctt ggccgtccca tctggtgtca aaaggatatt ttgaggtttc aagtccctgt
    36721 gaacaattcc tcgagtatgg gccaagcgca tagccaagag aatttgtccc atgatacgga
    36781 ctgcttcttc attagaaaga ggataatgtt ccttgatata gcgtttgagg tctagtccag
    36841 caacatactc cattgcaaga tactgttgac cgtcttcctc accaatatct gttatccgaa
    36901 cgatatgagg atggtctaga tctgccatag ctctcgcttc acgctgaaaa cgagctacag
    36961 ctatcgggtc cgtctggtag ttggtcctca gaaccttcac tgccacttct tccccatcta
    37021 agattaagtc tttggctagg tagacatccg ccatgcctcc tcgaccaatc tgtttgacaa
    37081 tccgatagcg tccggcaaaa atcttgccga tttggatcat tcttcatcct cctcgttcat
    37141 agaaacaagg gcaaccgtaa tgttgtctaa acctcctgca ttgttagcaa aacgaacaag
    37201 tgtctccgtt ttatctgcta aaggaatatc actggttaca atatcacgaa tctcactgcc
    37261 tgaaatcatg ttggtcaagc cgtcactatt gagcaagaga tagtcacctg actcaaggat
    37321 aactgtccca aaatcaggct gaatttcatc tttttgccca atagactggg tgataatatt
    37381 tttttgcgga tgagcttctg cctcttctgg tgtcaattga ccagccttga gcaattcatt
    37441 aaccaaggaa tgatcgctcg tcaactgatg gtattcttct ccacgaatca agccgatacg
    37501 cgaatcacca atatgagcat agatagcctg attatcaata atagcaagga cttccaaagt
    37561 agttcccata cctctgtaag cttcatcctg accaagctgg tgaatctttt gattttcaat
    37621 ttctaggtaa tgggcgaacc attcacgcac ttcattgact gtatcgatct gggtatcaac
    37681 ccaagctaca cccaggtctg tgaccgccat ttcactagcg atattccctg cacgatgacc
    37741 tcccatccca tcagctaaaa taatcatggt acgtccagct ctattgacat agtggttgac
    37801 atagtcttgg ttatttgttc gtttctgacc aacatctgtt aataatgaaa tttccatgtg
    37861 tcagttcctt cctaatccga tatcttgcga aattgactga tgaagaatcc atcacttcca
    37921 tacaattcag gtgtaatgag gatacagccg tctttcatga tatccttaca ttcatgttct
    37981 agttttacct gctcgaactc gggatgactc tctaaaaagg ccttaacgac ttgaaaattc
    38041 tcctctgaga cgatagtgca ggtgctataa gttattatac cacctttgcc tagtatttga
    38101 caaacactac ctaatatttc taactgaatt tcctgcaagg acgcgaaatc tgccgtttct
    38161 ttattgtatt tgatatctgg ttttcggcgc aaaagaccga ttcctgaaca aggagcatcc
    38221 accaaaatct tatcaaagga atcctggtca aaaaactcat gcacctttct ggcatctaat
    38281 ttttgagttt gaacccgatc tgcaactccc agacgttggg cattttcttg gattaaatcc
    38341 aacttgtggt cgtacaagtc cagagcagta acctgacctg tcgtaagata agaggctata
    38401 tgggctgttt tcccacctgg agccgcacag gcatcaagca ctcgctcatc accttgtaaa
    38461 tcaagcgtcg gagcaaccag ctgactggac tcgtcttgga tggtaatggc tccattcgta
    38521 aacaaattat gccctgcaaa atgcccttgc tccttaacca gaccagtggt tgctaaaagg
    38581 gaattattcg cctccaacaa ggcttggatt tcctcttttc gacttaggtc tgttacacga
    38641 atactggctt tgtttcgcac taacaggctt tcaaagatgg cttttgctct ctcctctccg
    38701 tattcttcct tgagtttggc aactagccaa actgggagag aataggcaat ggagtcacgc
    38761 ttgttttttc gcttgatgct agcaatatct ggccagcctt cacgcaagat acggcgaagg
    38821 acagcgttga ccaatttttc actgcctttt ttacggagtt tggccaattc cactgcttca
    38881 ttgaccacag catgatctgg aatcttgtcc aaatagcgga gttggtaggc actcatgaga
    38941 agaaggacat agagccagct gtctaactgg tctctgtctt cgataaagtg ggataggtac
    39001 cattccagag tcagtttacg ggctaccgtt ccatagacca gctcggtcac taagcccttg
    39061 tctgctgcag agagctgact ccccttgagg tgtttattta aggcaatatt tgaatatgct
    39121 tgattcacaa aaacatcctc tagcactgct agagctaaac ttctagccgt ttctacttta
    39181 gtcaccaaat cgttctccta cagtcaatgt acgtccaact ccgttgagga aggaagcaat
    39241 gtccatctta ggcttaccag ctggctgcac ttgtttgagg gatagagccc cttcagccgt
    39301 tgcgacaatc aattctttct tgccgataga gagaatctca cctggatttc cctgaccttc
    39361 tactggtagg gcttcataaa tcttaaagcg gtcaccctta aggaaagtat gggcaacagg
    39421 ccaggggttc attccacgaa tttggttaaa gagttgacga ttggttttgt tccagttcag
    39481 tttttcttcc tctgacttta tatttggaga gaaggtaacc tgactcgtat cctgcggttc
    39541 aggtttgata tcaccagcaa tataggcagg cagagtgtcc aaaagcaaat cacgaccaac
    39601 tagcgccaat ttttcaaaca aggtgccaac attgtcctca tctgtgatcg gaatgctgcg
    39661 acgagaaatc atatctcctg catccatttc cttaaccatt tccatgatgg tcacaccagc
    39721 ttcctcatcc ccttgaatca aggcataatg gataggcgca ccaccacggt gtctaggaag
    39781 gagggaggca tgaacgttga cagcaaagtc catgctatca aggagtttgc ttgggagaaa
    39841 ctgcccaaaa gcagcagtca caattccatc tgctcctagc ttcataagat cttccatctc
    39901 tggacttcca gataattttt caggttgata gatagataat cctgcttcct tggcagcctg
    39961 cttgactggg gtttcttgga taactttttt acgaccaaca gcacggtctg gctgggtcac
    40021 aacggctaga atttcgtaac ggtcatctgt caaaagtcct tttaagactg ttgctgaaaa
    40081 gtcgggggtc cccataaaga ttagttttgt catatcttct ccttcttata aaaattgctg
    40141 cggctcatgg tcaatgctga gacggagctc actattttcc cgttcttgag tcaaggccag
    40201 gacctggttg agggtcggcc ccagctcatc ttctaaacgg tatttaatta aaatctggta
    40261 atgatagagg ttgtgggtac gggcaatcgg ttttggcgtt ggccccagaa tgggactggt
    40321 ctctgacaag cctgaccgca aaatgttcat gacttcatag gcacgtttga aaacctcttc
    40381 ttctttcttg tgagaaaggg taataccaat cgtgaaatag taaggtggat agccgagttg
    40441 tcgtctgatt cccatttcat aggcataaaa gccttcgtaa tcttgatcct tggcaaatcg
    40501 aatagcatag tgctgcggat tgtaggactg tatcaagact tgacctgctt tttcagcccg
    40561 acctgctcga cctgccacct gagtcaagag ctggaaggtt ctctcagaag aacggaaatc
    40621 aggcagattc aaggccgtat ccgcatttag aactccgact agggtaacat tgggaaaatc
    40681 caaacccttt gcaatcatct gagtaccaag taaaatatcc gcttcccctc gcccaaactg
    40741 gtcaagcaag gcttggtgac tgcctttctt tcgagtcgta tccacatcca tcctcaaaat
    40801 gcgagcttgg ggaaagagtt ctgctagctc atcataagcc ttctgagttc ccgtcccata
    40861 gtaacgaata ctgtggctct tacagttagg acagacctga ggaatatcct tcgagaaacc
    40921 acaataatgg cagttcatag tcttggtatc catatgcaag gtcagagaaa tatcgcagtt
    40981 gggacaagta tccaccgtcc cacactcccg acacatgaca aagctagaat aaccacggcg
    41041 attgagcatg agaaccatct gctctttttt aaccagacgg tcttggatag cctctagcaa
    41101 aggaggcgta aagtttgacg tctcattttg tccgatatag tctcgaaagt caatcacttg
    41161 aacctcaggg attgtagcca aaggattggc acgttgggtt agacgtaagt gttgatagac
    41221 gcctttgcca gcacgtgccc ggctctctaa gctcggcgtt gcagatccaa gtaccagagt
    41281 tgcttgatta tactgagccc gtaaaatagc tacctctctg gcatggtaac ggggattgct
    41341 gtcctgctta taagccgctt catgctcttc atcaataatc atgacaccca gatttttcag
    41401 aggagcaaag atagcagatc tggcaccaac aacaacttgg gcatcgccac gctccacctt
    41461 gcgccattca tcatactttt caccattgga taatcctgag tgaagaatgg ctaccttgtc
    41521 cccaaaacgt gctataaaac gctcggtcat ctgaggagtc aaggaaatct caggtaccag
    41581 caaaatagct gtcttgccct tatccagggc accttggata atctgcaagt aaacctcggt
    41641 cttcccactt cctgtaatcc cttgaagtag aaagggaggt tgagaactgc caatagaact
    41701 cacaaccgca tcacgcgcct gtctttgttc tggatttaac tccaaaggtc tacttgcttc
    41761 aattccttca aaataagcag ccgagcgtcg aacttccttt tggactatag taacagcacc
    41821 ttgatccaca aagaagttaa cttgctctcg cgagtaggac tctaacaagc tagccaagga
    41881 agcgctctct ggatgagaca gcagataatc tctcagttcc aactttttct tggcacgtgt
    41941 agaaatctca acaccttcta attgagcatg gtcaacctca taccaagact gggtcttgac
    42001 cttcttttga tcgactgcct gatattccag accaagcagg ccttttctag tcaaacgcat
    42061 catttcagct tgcttaccta aatccagaga agaaaaggct agcgaatctt ctgaatcaaa
    42121 caggcgtact cgttcttcct gactcaagcc ttccagagga tagagaatct tgtcatagct
    42181 agaattcaga aatcccggaa gcatggcctt gaggatagag attttgtagg agaagacaga
    42241 tttgcgtaac tcctcagcca gccagagttg ttctggcgtg agaacaggag aaaaatccag
    42301 cacctctgca atatctttta aatcttgctc catctcttct ccatctgatt gggactccaa
    42361 accaagaaca atcccttgaa tcaggcgatt acccttacca aaaggcacat gaacccgcat
    42421 cccaacttcc agcattccct caaattcctc cggaatcctg taactatagg gctggtccgt
    42481 ctgcatcaag ggcacatcta cgataatctt agctagggcc atcttctcac ctcctccttg
    42541 tcagtacatt cttgcaatag aaaaaataag attgagtccc cccaacctta aattttttca
    42601 ccatcttctt tttctttagc aatttgctct ttgattttct tttcttcttc ttctttgcgg
    42661 cgtttttctt cttcgatacg gcgacgcact gcttcacgtt ttccttctgg atctgggtga
    42721 attgtaacgt ttcctgattc gatttcttct aaagcgcgaa gagttgattt ttcagacttg
    42781 aaaccttgag ttgctggggc acctgcttcc aattcgtggg cacgttttgc ttccaagatt
    42841 acgagtgaat attttgaagg aaccttgtcg agcaaggtat caatagaggg ttttaacatc
    42901 atttgcttgt acctattttc taaattttat cgggtagttg gagattttgg taacatctcc
    42961 tgatagtgac caatgacacg atccacacag aagtgttctg cttcaatcac acatttgaca
    43021 cgttcagcag ctaggggcac ctgatcgttg acaatcgcat aatcatactc acgcatgagg
    43081 gcaatttctt ccttggcctt ttcgattcgt tgggcaatca cttctgcact atctgttcca
    43141 cgacctacca agcgatcttg caattcatcc aaatctggtg gtgtcaggaa gataaagaca
    43201 gcatctggaa cctttttctt gacctgaaga gcaccctgaa cttcaatttc aaggaaaaca
    43261 tcgattccct tgtccaaggt ttcattgaca taggtcagag gagttccata gtagttgccg
    43321 acatattctg cgtattccaa catctgtcct tgacgaatca gctcttcaaa ttcttcacga
    43381 gtacggaaga aatagtcaac accgtccact tctccaggac gttgtgcgcg tgtcgtcatc
    43441 gatacagaat attgaaattg gttttcagaa ctctcaaaaa tctctcttct aaccgttcct
    43501 tttccaaccc ctgaaggacc agaaaaaacg attagtaagc ctcggtctgc cattgtgtct
    43561 ccttttagtc aatctgtgaa ataacatttc tctagaataa tggcaaaaag ccagattatc
    43621 ctttacagtc tttctatcta gtgtaacaaa aaagcagtaa tttttcaact gctctttctt
    43681 atttatttag cataatctac tgcacgaagc tcgcgaatca cggttacctt gatatttcct
    43741 ggataatcga gattgttttc aattttctta cgaactttgt gagccaagat tgtgactttg
    43801 tcgtccttga tttttcctgg attgaccatg atacgaattt cacgtcctgc ttgaagggca
    43861 aagctagttt gcactccttc aaagccgtta gcaatttctt ccaaatcatg gagacgcttg
    43921 atgtagcttt caagagactc actacgagca cctggacggg ctgcgctcaa ggcatctgct
    43981 gcagcgacga taactgctat cacgctctca gcttcaacat ctccgtggtg actagcaatc
    44041 gtattcacca caactggggg ttccttgtac ttacgggcca attccatacc gatttcaacg
    44101 tggctacctt caacctcatg gtcaatggct ttcccgatat cgtgaaggaa tccagcacga
    44161 cgggcaagag ccgcattttc accaagttcg ctcgccatga taccagccaa cttagcaacc
    44221 tcaatcgaat ggcgcaaaac attttgtcca tatgaagtac ggaactgcaa acgtcccata
    44281 atcttcatca agtctggatg aaggtttggc gcaccaattt cataggcagc agcctcaccg
    44341 tattcacgaa tcttattgtc aatctcttga cggtttttct caaccaactc ttcgatacga
    44401 gctggatgta tacgaccatc tttgagcaac atttccatag tcatacgggc aatctcacga
    44461 cgaatcggat caaatcctga caaggtcacc acttctggtg tatcgtcgat aatcacatcg
    44521 acccctgtca aactttcaaa ggtacgaatg ttacgacctt cacgaccaat aatgcgtccc
    44581 ttcatagtat cgtctggcag atgaactgtt gagtttgttg actccgctac atattcacca
    44641 gcgatacgtt gcatagcttg aaccaagatg tccttggcca ttttgtcaga acgttccttg
    44701 acctcttgct cagcttcgcg aatgcgactg gcaatctccc tggtcaagtt ttcctctgtc
    44761 tgagccaaga taatatctcg tgcttctgcc tgagacagag caccaatacg ctctagttct
    44821 gcttcttttt gtctttcgac ttcctctaat tgctcttcac gcgcatcaag gtttttcgct
    44881 ctatcagaaa tactttgttc tttttgttca agtgtttgtt ctttactcgt caaattgtcg
    44941 tccttacggt caaggctagt agctctctct gtcaaacgac tttcgatttg tttgagttct
    45001 tgacgttctg atttgaattc agcgtccact tcttcacggt attttctggc ttcttctttg
    45061 gcctccaata gtgcttcttt tttaagagac ttgctttcac gtttggcttc attaacaagt
    45121 aaatccgctt cacgctcagc ttgtccacgt aaattagttg cttcttgttc agcatttaaa
    45181 agcatcaact ctgcagcttc ctgagatgat ttcatcttag ctgagatgct gacatatcca
    45241 atgactaaac caatgatgac ggcaaaaaca gcaatcgcaa gcgacatgat ttccatgttt
    45301 ttacctcatt ttattgttat tccgaatgac atacattctt ttacattcta ccataaaaaa
    45361 gtgattttca caaacctaaa atagaatatg ttttggggaa tttggaacac atttgccaaa
    45421 ataaacttgt tttttagaaa tagtagttta gtagagactt gagaaaaagc ctacctttca
    45481 atagacttag taatgatctt taaaggacaa gaaagccacg ctatctccat ccatcatata
    45541 aatcaagcga ttttctgcat caatacgccg tgaccaggct ccttggtaat catatttgag
    45601 tggctctggt tttcctattc ctgtaaatgg atcgcgttga atatccttga ttaatttatt
    45661 gattcttttt agtgtttttt tatcttggtt ttgccagtag caataatctg cccacgcatc
    45721 ttctgtaaac ttgagtagca ttcatcactc ctcaatcaca tggacctgaa tgcttccagc
    45781 acggacttga gccattcctc gcaaaacctt gtctgataac tccttatttt gagcgattct
    45841 cagggtttcc tgaatactgt cccattcgct ctttgaaaga actacaatgt cctcatctgg
    45901 atttttattg accaccgtca aaggctcaaa ttcatcattt accttcttca tgtagtcctt
    45961 taaatgattt cggaatgttg agtaaaggac tgcttccata accatacctc gttttagctc
    46021 ttttccacta ttatacacga aaagaaagaa attgtcagga acttgtacaa gattttcttt
    46081 tctatctatt tatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgt
    46141 acttgagtac ggcaaggcga cgttgacgcg atttgaattt gattttcgaa gagtattatt
    46201 cgtaaaaaat ctcaaaaagc ctacctttcg gtagacttag cttgtttcta ttctaatcgg
    46261 cactcttcca aaattttgct ctgctatact tggctttcct agttggtaaa tctggtctgc
    46321 tttttgggtc atagcatccc aaggttcttt gccaattcgg ctgactagat tgacctgtcc
    46381 tttcagagac ttgagatgtt gcctgccttt ttcagtaaat ccaaggacat gaatggcttc
    46441 tggcaagaca ttttctctag cctgcaccaa aatataggtc aataggcgtc tgacacgcgc
    46501 cttggtgtaa cgtttggtcg caaccgcctc gaccaactct tctacagact gggctgtttt
    46561 aatagcttct ttaatgcgca cagccatttc ttgattgacc tgatagatgg tggttaggtc
    46621 gggatttgac aagatttgat agcggagcaa gggaaaatag tcttcccaga tcaccttact
    46681 ggcctgctca aatagggcaa cagaaggcat aaagcgttct aagaaatctt ggtccttctg
    46741 atgttgacgg agggctgtcg ccgaggcaaa gtccacatct ttattcacag aatggtaacc
    46801 tgccccctga cgctgaatcg tatgcagctt gatatttcgt cctgcaaccg cctttgcata
    46861 ggccagagca agaacatgat tgggggtatt acctgaaaaa tcaagaccag caaattcctt
    46921 ccacatagat tgggttttct ggggatagga aagggaatca ggcagatttt ccacaaattt
    46981 ctccatctca gcacctttct ctgtgtataa gtcagcgatt ttctgataat ctcgaacttc
    47041 ctctgtccca aaaactagac tatcaatgcc caagcgatcc aagatatcca cagctccttg
    47101 accaaagaaa tcagctgcct gaacactgac taaaaagggc aattccacta ccaagtctgc
    47161 gccattttcc agcgccatct gggcccttgt ccacttatcc acaatagcag gctctccacg
    47221 ctgcatgaaa ttccctgaca tggcaacaat tttcagtccc tctgcctgat ccagcaggta
    47281 tttatggcca ttatgaaaag gattgaactc tgcgataata cctgtgatgg tcatgatgtt
    47341 ctcctacttc tgcgccacaa aaaaccaacg ggtgctagtt tctgttggtt ccttatcctc
    47401 aaagtctgca tagagtttga aggacttgaa tccagcctgt tccagcaaga tatcataggt
    47461 caagatctca taagtcctct cctcatgtac ttcatcgtgg cgactaaagg aaccgtcagc
    47521 ctccttgata aagaaagtca gctcatgcac gatggagtga ggagcttcgt cctcatatgt
    47581 atcccaaagc atggcaaaat cttccgcatt ttcatggtag gaatagccag ggaatacttc
    47641 atctgtctgg taggtcgagt gcacgtcaaa gatgaaaact ccctcttcat tcagcgcatt
    47701 gtacacgtcc ttaaagacgt cccctacttc cacctcatcc tgcatatagc agatagagtc
    47761 cgaataacac gtgacaaaat cgtatttccc tgccttggac aaattcagca tattaccttc
    47821 tataaaagca atcttttgct tggctgaagt tgctctcttc tccgcaatct tcaacatatc
    47881 cgcactcaag tcaagtccag tcacatcaaa accagcctga gagaagcgca ctgattgaat
    47941 tcctgtccca caagccaatt ccaagagttt ctttctctcc ttggtcttag gcaaatgacg
    48001 cagagaaaaa ttcgtccatt tgtcgtataa actatcgtcc atgaccgcat catagaccgc
    48061 cgcaaaggtt tcataagtcg ccataatcat gatactaaga gctccatggt aaacaccact
    48121 agccctttac ctttctatca atttttctaa aataagcaaa gaaacccagt tgactacaac
    48181 tgagttcatc ttctaagcaa gagcttctga aatatctact gaattcgcct catgccatag
    48241 cttctctaga ttataatggg cacgcatttc ttctgaaaag atatgcacga caacagcacc
    48301 gaggtccagt aagacccagc ctccagctgc atcgccttcg acatggctac ctttaaagcc
    48361 tgcttgagct actttttcac ggatattagc tgcgatagcg tccaactgac ggctattcat
    48421 tgagctagtg atgacaaagt agtccgtcac actagtcaaa tcttgtacat caagtgcgag
    48481 gatatcctcc gcacgtttct catcagccgc tttcacgact agttctagta attctttttc
    48541 gttcatttaa tcctcttttt agaaaatatg tttgtaatct agaacatctg caaagcgctc
    48601 ctcccaaatg tcctcataaa attcattaat cgtttctgct ggaatgtcat ccccatcaaa
    48661 ggttgtgaca gcaccttctg gaacaataag ctgatagcca tattcaaagg caaccttgac
    48721 agaggtatcc acacaatatt ctgtctgcat accacataaa actaattttt caatcccctg
    48781 cttatccaag tattctttta agccagtttc tttgaaaata ctgttatact tcttctgaaa
    48841 gaccttttca gcaggttttc gatttaaaag cgcagataac tgccaatctt ctgatgtttg
    48901 agcttcagag ttctcaatat gttgaacata gataatttca atattcttgc ttctagcctg
    48961 gttttgtaaa taagaaattt tttccaatag actttttgtc tggaacccag tttctactaa
    49021 aacattctga acatcaatga ttataaaagc cgtcttcatt tagtcctctt tcaaatagtg
    49081 cacaaaggcg ttataggttt caagggtttg gggatagatg gggaatccct gatgagctag
    49141 atactccacg gtacgagctg tttcgtaggc caccgcctta ttgagcgata gacttgcaat
    49201 ctcacgcgcc acatccactc caggaaatgc ccgattgtgc tcgatatagt ctgcgacgta
    49261 gatgacctta tctaggtctg tcatttgacc agctccgact gtatgaattt caatggctcg
    49321 cagaatttca gaatcatgca aatccaaatc ttcctgaatt ttgtaaattc cgaccatacc
    49381 atgccagaca ttattacccc agtttttgag gtcgaaatct agctgataac ggtcaatcaa
    49441 gtctagaaat tcctgatctg acaacttttt agcatagtca tgaagaagac ctgctagact
    49501 tgctttctca acatctacac caaagcgctg agctaattcc atagcggcac gctccacacc
    49561 tagacaatgg gttagacgtt tctcaggtag aagctctgcc attttttcca acaaggcctc
    49621 acgggagcag ttgatatagt cttgatagga catcagtaga gcccctcctt ctcgatgtag
    49681 tctagcactg gctgaggtag gagaaagttg ggtttccgac cttgggcaat gaagtcccgc
    49741 accatgctgg acgagatatc catgagcggt acgtccaccc agataactgg ataggaagtc
    49801 cctgccttgt agcgtggacg ctgaaccccc acaaactgaa ccatgtcaac cagttcatca
    49861 attcggtacc acttaggcag atagtcaacc atgtcggcac cgatgataaa gtaataatcc
    49921 gtatctggat tcttctctgt caaaatcttc atggtgtcgt aggtgtagga aatacccttg
    49981 cgctccaact caatggtttc aatgactagg ccgtcaattc cctcaattgc caactcaagc
    50041 atcttgagac gatggtgttc agggatggtt tcctttttat caacgtgagg aggttggtat
    50101 tcaggcatga gaagaacttg atccagtccc aactgttgcc gtacttgatc cgcaacaatg
    50161 agatgggcat tgtgaacagg gttaaaattc ccccctaaaa tcccaacttg tttgcgtttt
    50221 ttctccttga tttctggctc caactctacc ttggtaaagg gagtcaatag ttcgattgtc
    50281 ataggctagt cccctttatt tctctataaa aacagttatt tggagtttcg gtcttagatt
    50341 tctttgactt tcttagaaat cttgcgattt tctttcttgc tagattgttt aaacaaaatc
    50401 aagatgcgtc ctattttttg gactgtatcc acaccgattt cttcttccaa aatttcagct
    50461 acttcgtgga tgttttcatc tgtgttttgt aagagagtaa ccttgattaa ttcacgcgca
    50521 tcaagagctt gacggacgct ggttttgatt tggtcgttga gtccattttt cccgatttgg
    50581 atgataggtt tgagggtgtg tgcctggctg ttgaggaagg cacgttgttt tgatgttaat
    50641 gacataattt ctttaaaaga gtttcttttt atacttttct gaagtggtga cggacgtcag
    50701 caaagtcctt cggactttca tgactaaaat ttgagcctaa ggtctcaaat tttccgcagt
    50761 tggtacaatc acttgtacca acttacacca cagcgaaaag tattctctat ggggctcgcc
    50821 ttgctcgccc aaattcagac aaccctttcc tttctgtgct taaataattg cttttcgtgt
    50881 gacgacggcg acgccttctg gtgcccagac ggcgactttt gctatgcctg ttacacgaat
    50941 ccagcctagg cctgaaatga ctaggtctgt cttatcttta atggtaaaga catgctggac
    51001 tagccttggg aaatcttctt tttccttgct atttggtggt gtcagaagag ttcccaggtg
    51061 cttatcgtag aaagcactag ctccttcaag cttgctacga tggagtttga gttcattatc
    51121 aaagaaagca gtaaatcctt gcttttctcc tgctataaag tcaaagcgtc ccaaaccacc
    51181 taaaaatagg gtttgctcag gattaagctg ataggtctta ggcttgattt cctttttagg
    51241 actgacatac ttgaggtttt tggccgtcaa gtagtgagcc atctggtggc ggtggataat
    51301 tcccggcgta tcgtaaatat aagatccgtc gtcaagcgga atctctattt tgtccaaggt
    51361 tgtccctggg aagcgtgaag tagtgatgac attctgatca cccgtgattt cttggataat
    51421 agcattgatt agagttgatt ttccaacgtt ggtcacaccg accacataga catcgcggcc
    51481 cttacggtag tgttcaatct tgtcaatgac ttccttaatg gcatgtttat tttgtgctga
    51541 agttaggacc acatcgactg gacgaagacc ttcttcatag gcacgtttca tgagccactg
    51601 gctaatctta ccagacttaa ctgacttagg aaggatatct tttttatttc ctaccaagag
    51661 gacatcattg cccgagacga aacgtggtaa acctgggatg acagatccat taaaatcaaa
    51721 gatatcaata acattgacca ctaaagcatc actgtctccc acctcgtgca agagcttgag
    51781 gaaatcatcg ttcgtcaact ggacatctgt gatttcattg tagtggcgga gacggaaaca
    51841 gcgttggcaa tagacttcgc cagtctccaa acctttttca agtgccgact ggggggtaaa
    51901 accaagacca gctttatctg tcgtctgaat ggttgctcca caaccaatac agagaatttc
    51961 ttccatagtt aaattccttt tttatatgta atcggtccgt acttttcagt gatttttctc
    52021 ataacacgac gctcacgagt tcggttaatc tgcgttttga ttgagtcatg ttggaccaag
    52081 ggtttgacta aaattgaccg aatccctgca cggtgggctg ctcgtatatc tgtcatgagc
    52141 tggtcgccaa ccatgaccac ttcctttttg tcatagtgga attccttcat agcacggtca
    52201 ataccaaatg tgaagggctt caaggcccag taaacgtaat caatcccaaa tttctcaact
    52261 gctcgttgaa cgcgtttttt ggtgttattt gacactacga taatgccaat acccgcgtcc
    52321 cgaaggtcat gtagccattg cttcatctct ggcgttccat cagggttgtt ccaagcaatg
    52381 agggtattat ccaaatcgac caaaacagcc ttgattccct gcgcctgcag gcttgggact
    52441 gtcagatcat agactgcttc cacagcaaaa tctggtatat aattttcaat cgccattctg
    52501 gctccttttc ttaacttttt ttcgcaattt tccttagtaa caaggataaa acaatccaca
    52561 aacctgcact agccaaactg atatagagcc aagcatgggg ctcatctgtt aaaggtaagg
    52621 gaacattcat tccgaaaaag cctgtcacga ctgccaaaac agctagcaag actgaaatga
    52681 tagtcaaggt tgtcaaattg tcattcagat tattgtttag aatattgttg taagaggctg
    52741 aaagctgctg taaaatctga gagattaggt ctgtcatgga taccagctga tgagcctcaa
    52801 tcatggcatc atcaaactgt tctctctcaa tctcatcaaa actacgatac aaggcatgac
    52861 cttgaatatg ctctaacaaa atccgatttt gtttggcagc tgccgtcaga taaaccatac
    52921 cagtctccaa atcagacagg gcaaagaggt ttttcttggt agttcgctgg cgcaagaggt
    52981 cattgacctc atccctactc ttgtccatct gctcaatgac aggatagtag gcattgctga
    53041 tgatttccag actggcaaag agaaacttat aaatcgaaag cgtgtcatgg ttctccagat
    53101 aacgagtcat ctgttcaatg acataggcgt tcttggtatt actaatggta atcaggcgac
    53161 gatgctcgac gataaaggtc atgggaaaag tctcatagta ggccttgtcc ttttttacgt
    53221 ctaggacatt atagataaag gtaaccgtcc cactttcacg gtggtagtcc atgtgggcgc
    53281 gctcgtttct atccagtgcg tattcaatgg tttccttgtc caaaccgtaa atttcagaaa
    53341 ggtcttctag tttattcaac tttcctaggt ctaggtctat ccaggtacaa ccattgccca
    53401 actgcttttc taaaaccatc ttttctcctt attaaactcc ctctattgta ccacaaatta
    53461 cttaaaataa caggtctagt ctgtgcgtga gaaattgcta acaactgtga tatttcggtt
    53521 agggacaaag tgaagggctt gctcctcgct acgaagctgt gtcgtacgaa ttcccacact
    53581 gacaacctta cccgatacag taatcggtcc atttgtcaga acgacctcat ctcccacatc
    53641 cagttgacgt tcaaagagga taaaaaagcc attaatgaca tcagacagaa agccttgggc
    53701 tcccatacca atcgctaccc cagcaatacc agctccagcc agcaaactag aaactggcaa
    53761 acctaaaatc gacaaaatgc agtagagtaa aaagaaatat agcgtataat taaacacatt
    53821 ttctagtaaa cgtgagatgg ttttttggcg tccgacatca tgacgagaca tttttagaga
    53881 aggtttgaca attctctgca ccatggtatg aagcattttt ttagcaatat aaaatacaat
    53941 caaaagcagt aaaagagaaa tgaccttggt tagaatattc tcgataatgc ttgtcacatc
    54001 tagcttttca atataagcct gaataaattt ttgcatataa aactccttta tttcattata
    54061 ccatattttc atcagtctca ttctccataa atattcaaaa aatagacaga aaattcttga
    54121 ttttgtctat catttatact ataatcataa tcactacaca aaaaggagat tattatgaaa
    54181 agaatcattc atgcttggaa taaggcaagc cttgtcaagc gtatcttgat tggtatgctt
    54241 tgtggggaat cctagaactg acccttccta atctctcagg gattgggcta ctcggggatt
    54301 tattcgttgg aggtctaaaa gctgttgctc ctatcctagt ctttgccctc gttgccaatg
    54361 ccctttccca acatcaaaag ggacaagata gcaatatgaa aactgttgtt ttcttgtata
    54421 tcctatgata gagactttcg acgctgctct tgtagctgta ctagcaagtt tcatcgtccc
    54481 tattgaaatt accctaaata gtgctaatac tgaaattgca ccaccagatg ggattgggca
    54541 ggtcctcagc aacctcttgc tcaaactggt tgacagccca gtcaacgccc tgcttactgc
    54601 taactatatt ggaatcttat cttgggcagt catttttgga atcgctatga gagaagccag
    54661 taaaaccagt aaaaatagta aagaattgct aaaaactatc gctgacgtga cttctaaaat
    54721 tgtcgaatgg atcatcaatc tggctccatt tggaatcctt ggtcttgttt ttaaaaccat
    54781 ttctgacaag ggagtcggaa gccttgccaa ctacggtatt ttattggttc cattagtaac
    54841 gactatgctt tttgttgccc ctgtggtcaa ccctttgatt gccttcttct ttatgagacg
    54901 caatccttac tctctagttt ggaactgcct ccgtgtcagc ggtgtgacag cctttttcac
    54961 tcgtagttct gcgactaaca ttcctgtcaa catgaaactc tgccatgacc ttggactcaa
    55021 cccagatacc tattctgttt ctatcccact cggttctact atcaatatgg ctggagtagc
    55081 gattaccatt aacgttttga cccttgttac agttaacact cttggaattc ctgttgactt
    55141 tgccacagcc tttgtcctca gtgtggtagc agctatctca gcctgtggtg cttcaggtat
    55201 tgccggaggt tccctccttc ttatcccagt tgcttgtagc cttttcggta tttctaacga
    55261 tattgccata caagttgttg gggttggttt tgtgattggt gtcatccaag actcatgtga
    55321 aacagccctt aactcttcta cagatgtcct ctttaccgcc gttgccgaat acgcagcaac
    55381 ccgtaaaaaa taactcatca aggcaagcct gctcatgtct tgtcttttac gcttttattc
    55441 taacttatta ggaaattctt atgtctatta gccaacgtac gaccaagctc atcttagcta
    55501 cctgtcttgc ctgcctgctt gcttattttc tcaatctttc gtcagcagtt tcggctggaa
    55561 ttatcgctct cttgagccta tctgatacgc gtagaagtac tttaaaactg gctcgcaatc
    55621 gtcttttttc tatgcttcta gctctggcta tcggtgttct agcttttcac ttgagcggat
    55681 ttcatatctg gagtctcggc ctctatctgg ccttctacgt tcctttagcc tacaagatgg
    55741 gctgggaaat tggcatcaca ccaagcactg ttttggttag ccatctcttg gttcaagagt
    55801 caacctctcc agaccttcta gtcaatgaat tccttctctt tgctattggt acaggatttg
    55861 ccttgcttgt taatctctat atgccttcac gagaagagaa aatccagcac taccacacgc
    55921 tggtggaaga aaagttaaaa gatatcctcc agcgcttcaa atactattta tccagaggag
    55981 acggacgcaa ccgagcacag ctggtagcag aattagacac gcttttgaaa gaagccctca
    56041 gactggtcta tttggatcac tctgaccacc tctttcacca gaccgactac catatccact
    56101 actttgagat gagacagcga caaagtcgta tcctgagaaa catggcccaa cagattaaca
    56161 cttgtcacct tgccgccagt gaaagcctga tcttagcgca actcttttca aaaattgcag
    56221 gtcaactgag ccagaccaat cctgcttctg atttgctaga tgaaattgaa cgttatctgg
    56281 aagtcttccg gaaccgcagt ctgcccaaga caagagaaga gtttgaaacc cgcgccactc
    56341 ttcttcaact cctacgtgaa gccaaaacct tcatccaagt aaaagttgat ttttaccaaa
    56401 aatatggaca gtaaaaaaga aaaccactaa aaaacagagc ttgccagcat tcttgaaaag
    56461 tagtataatt attgcatgcg caatcatctt gtgacgcaga gactgcccgt taatggactt
    56521 tcttctatat tatgactcta aaaagaaagg agacactatg acctatttgg aaaaatggtt
    56581 tgacttcaat cggcgtcaga aagaaattga aagtctcttg gaagagacca ttgcccaaca
    56641 gagcgagcaa agtctgacct tgaaagagtt ctacctgctc tactatctgg acttggctga
    56701 agaaaaatct ctacgccaga ttgacctgcc agataaactt catctgagcc cgagcgcagt
    56761 ttctaggatg gtggctcgct tggaagctaa aaattgcggt ctactcagtc gcatgtgttg
    56821 ccatcaagat agacgctcta gttttatctg cctgacaaat gatgggcaaa agacactggc
    56881 ctcgctacaa aaaactgtcg aagaaagctt ggaagcaggt ttggatttct tgatttaaga
    56941 tgatttttaa aaaaagttgc gtgcgcaatc atttttcttg acattctctt ttataaggag
    57001 taaaataaag ttagcattaa acaaaggagt tttaaatatg attgaaatta cctatataga
    57061 tgccagcaag aacgaaagaa ctgtgacttt cgagtcttat gaagactttg aacgttcgca
    57121 acaagcttgc cttatcggcg tcgcagacta ctaccctgtc caaaaattaa cttacaaggg
    57181 tcataatttg gactaccatg ggacttatgg agatatcttc ttctatctca tgaaacaaga
    57241 tttaagccaa tataactaaa aaaaggagaa atacaatggc aaaagcaatt acagatgcaa
    57301 cattcgaaca agaaacaaaa gacggtttgg tcttagtaga cttctgggca acttggtgtg
    57361 gtccatgtcg tatgcaaggt ccaatcttgg acaaattgtc tgaagaactt tcagaagatg
    57421 tcttgaaaat cgttaaaatg gacgttgatg aaaatccaaa cacagctcgt gcttttggaa
    57481 tcatgtctat tccaactctt ctcttcaaaa aagacggcca agttgtcaaa caagttgcag
    57541 gtgttcacac agcagaacaa atcaaggcca tcattgctga attgagctaa tcaaacgaga
    57601 gaccaagtac tttctttggt ctcttttttc ttgccctttg ctatttttca aaaaatatgc
    57661 tagactatag tatattgaaa ctagaatagt acgcctctac ttctaaaaca ttgttagaaa
    57721 tcgatttgac tgtcctgatc gatttgtcct gttcttattt cattttacta tataagtaga
    57781 atattacgat gtttgggata tgccatcgct aaaaaaacct cgatttggta ttttttagct
    57841 ccctaatggg agctttttgc gtgctctgaa catttcccat tttggaagga gtactatgaa
    57901 acgtcaatca gccttggtcg tctttagtgg tggtcaagat tcaacaacct gccttttctg
    57961 ggccatgcaa cactatgaaa cagtcgaagc tgtcaccttt gcctacggcc aacgtcatca
    58021 cctcgaaatt caaattgcta gagaaatcgc taaggaacag ggcattcgtc accatatcct
    58081 cgatatgtct ctgctgggac aaatcactgc tcagccagac tttgcgacga ttcatatttc
    58141 ctacattcct gacaagctct gtgtcgagtc aaaacccctc aaactatatc tatttagcta
    58201 ccgaaaccac ggagatttcc acgaaaactg tatcaacacc atcgggaaag acttggtcaa
    58261 cttgctagac cctcgctatt tagaagtctg gggaaaattc actccgcgcg gtggcatttc
    58321 aatcgacccc tactataact acggtaagca aggaactaag tatgagggct tggcagaaca
    58381 acgcctcttc caacacgacc tttatccaga gaaaattgac aaccgctaaa ctcatactca
    58441 atgaaaatca aagagcaaac taggaagtta gccgcaggtt gctcaaagca gtgttttgag
    58501 gttgtagatg aaactgacga agtcagtaac catacctacg gcaaggtgaa gctgacgtgg
    58561 tttgaagaga ttttcgaaga gtatcatacg aaaaagccct gttcctcaag atgaggagca
    58621 aggctttttg agtttcaatt attcttctgt tccaaggaaa ttttttgcaa caagggctgc
    58681 aagaactcca ccagcgattg gtgcaaggat gaaaatccaa acttgttgaa gggctgcgcc
    58741 gcctaccaag acagctggtg ccaagctacg agctgggttt actgaaagtc cagtaatctt
    58801 caatccgaca agaatcatcg ccatcaatga caaaccgatt accaaaccag caatcgcgcc
    58861 attgcccttg ctttctgaag tcacagtcat gataaccaag acaaacaaga aagttgcgat
    58921 gacttcaaac aagaaaccac caaagacagt gacaccgttt gccaaggcat tttcaccaag
    58981 gctagcagtt gacatacctg aattacccaa gaggaagaag actgcgccag aagcgatgaa
    59041 agctccaaca acctgaccaa ggatgtagtt tacaagttct gaagatgaca aacgtttgtt
    59101 tacaaacata gcaatcgaaa cagccgggtt caagtgagca cctgaaacag ttccgattga
    59161 gtaggctgcc accacgattg ccaaaccaaa ggcaaaggcg attccaaggt gaccaaggcc
    59221 atcaaaacca tttccaaaaa caacagctcc tgtcccaacg aacacaagca tgaacgtacc
    59281 gattaactca gcaacaaatt ttttcatttt ctttctcctt ttttcaaaaa ctagatacta
    59341 gtctatcaaa agtaggaaag ggtttcaaga aaattgattg gaaatttttt gaaaatcata
    59401 gaactattag ctaatcccta gtattgaaaa gactggatag cttctttcag gtcatcttgt
    59461 aaactatttc tctggtcaag ttggacatag acttccacca gacaggatct aaagttggaa
    59521 aatttgtaaa aatcctccct ttcttctatc ggaaaatcaa cagtttttat ccaagaagct
    59581 acttgttctt gctccaactt cccttgtaaa ataggttcat agatcactct tgctaaacgc
    59641 caatcctcat catctgtaaa gcgaatcgac attcttttaa atagttggcc aagtatgtca
    59701 aatacttcat gaattctgtt tataggaaag tctggatgac agaccacctc tgtcagtaaa
    59761 tcggctccat gtgcaaaaga atgaatccaa ccatactgac ttgagaaacc tgttgtatcc
    59821 ttttcttttg aaagatagtg caagccttga tttgaaaaga cattacgaat ttctaattgt
    59881 aatccctgat aaaaaaccga ttgctggttg gcatctgcat acaagagatt tgcataaaca
    59941 agtgccctaa aagaacgttc aagtgttggc agacctacct tatcaatctc tttatctagt
    60001 cctacatcag atgaaacccc ttcagcaatg aaatgaaatt gctcctgtgt aaatagctct
    60061 tcctgaatcc ctctagcaaa gcttgtaaaa acaaggtcat cgcgaatttc tggagaagga
    60121 tctcccaaat gatcaagcaa ccactggatt tcctcctggt tataatttgg tttttcttct
    60181 gctatttttc ttagtaaatc ttgatacatg gtcaatacct ctacatttct agcaactgtt
    60241 caaaaaagca gtcttaaatg accttaccaa tttgtaaaat taagttaaaa agaaaaagac
    60301 atttatagtc agagaaacag catatttctg aaaagatata taaatgattt attccatatt
    60361 acaacaaata aacttgtaat gatagagcct tatcacaaaa atcacattcc tgtctcaaaa
    60421 attgcgaaaa actagttata ataaagtgaa ataaaaacta tacaaattga ttagggaatt
    60481 taaaacaatt tctaacaata ttttaaaaac tgaaccgtac tatttcaact tccataaatt
    60541 acaatattga taggcacagt tcccatacct gcccaaattc gaataacgtt tagtataaat
    60601 tagaatatga ctacaacatc acaaataatt agactatcta taatatctac gatgtaacat
    60661 atacatagga agcaccgtta tcaagagcgc caaggctatc aaccagataa gatgaagata
    60721 caaacctgtc acctcacctc cccatataat acgaatcatg cgagtagcat gatacaaggg
    60781 agaaaaccaa gtcaaatcac caagtattgg gggcaaggaa gtaatgggaa agaaggtatc
    60841 tgaaaacata taaagaggac ggattaccaa aacattgtag taattcagaa attccctaga
    60901 cggcgccaag taggtaaaga ttagtcccaa aacaccaaac aaataaccca ctataaataa
    60961 aatcagagga atcaataaca tcaagacatg aaaatgcgct gtgataagca tagaaatcag
    61021 ccaaaaaatc ccaccgaaaa tcactgcacg aatacctgcc cagatagcct gacccaccac
    61081 aatatcactc gtattgattg gcgtcatcaa tatagcatca taagtctttt caatcttata
    61141 ctggataaag gcattgaccg ttgtttctgc ggtggccgca gacatagcag tcgcagcaat
    61201 taaacctgta atgacaaaat cacggtagag cataccgtta acatgcgtca aataggcacc
    61261 aactccaaat cccattgcta aaagataaaa gagggggtcg ataaggttgg gaacaattga
    61321 aattttaaat aaatttctaa aactcatgta gttgcgtacc acaacgtgtc cgatggagtg
    61381 aaatgataac ttaaacatgc aagtcctcct tctctgtccc agtcaacccc aaaaaaagcg
    61441 tctcaaggtt gtcagcatca tacttgatga gcaagtcttc tacagttcct tcttctttga
    61501 tagtcccttg gtggagcatc agcaccctat ctgtcaaata ttcaatctca ttcatatagt
    61561 gggaagtaat aatgatggaa acacctaatt ccttcaactc caaaagttta tcccaaataa
    61621 tattgcggga ttgaatgtct aaaccaactg tcggttcatc taaaatgata atatcaggcc
    61681 gattgatgag agctcttgcc aagacaagac gtcgtcgcat cccacccgac agctgattca
    61741 ccatcttttg cgcatgtttg ctcagttgaa caaaatccaa gagagaatcg attctcttcc
    61801 taagttcgac agatgagata ccatagcata gaccgtgagc aaaaagatta tcataaacat
    61861 tcaaggtcat gtccagcata tcctcctgcc ctacaatacc cagacaagat ttactcttac
    61921 gacgattggt ttcaatattt tgccccaaga tatcaatctc tcctgaggaa attgaggtca
    61981 gtgagtaaat catctttaaa gtggatgttt tgccagcacc gttgattccc aagataccca
    62041 aacactctcc ttctcccaat tcaaagctaa ttcccttgac agcttcataa gaaccatatt
    62101 gcttttttag atttttaaca cttaacttct tcactctttc tttcccccac aaatagagca
    62161 tgttggatac tttgttaatt catctcactt ttgaaaaaat gttgagggac gttaatctta
    62221 agattaacgt ccctcaactg tggatactgc tgcaattact tttgtaattt tacctccatt
    62281 taaactcaga caataaaatt taaaatattc tctagtaaaa catttttaaa atctattttt
    62341 cttgtgcttt aattatagta taataaaaga tagaaaatca tcgatatatg aaatttggag
    62401 aaaattttta tggaaccaga tattttcatc atcacaaaac tcttatcaga cccttctcgg
    62461 atgcacattt tagatattct aatggatgga aaagctcaca cggttaacga aattgccagc
    62521 tttaccaaaa tcaagcaaca tactgtcagc tatcacctca aattacttac cgaagcgcag
    62581 gtaaccactc tacaaaccta tggacgtttt cattattatt ctttaaaaag tgctgccatt
    62641 gcagaaatgc tggaatttct cagcttctac tctcctcagc gtgatgtcaa aagttataaa
    62701 caacacattc acaaaaagga attaaaagtc gctcgcacct gctatgacca tattgctggt
    62761 gagcttggca tttccattac caattatctc ttgcaagaaa atctcctcag cgaatcagaa
    62821 aaagacttcc aactcactga agctgggaag tcttatttcc aaagaaaatt acacattgat
    62881 acggatgaat tgaaaaagaa aaaacggaaa ttttgcccta aatgtttgga ttggagcgaa
    62941 cgtaaaaatc atgtcggcgg agctctcggc aatgctcttt tagaattttt cagtgaaaaa
    63001 caattggtca tccctgcaca aacgccacgt tcacttacca ttacagagaa gggcaaagaa
    63061 ttcctcgaaa aggaatgggg gatttaaaca tggaatttta agcaaataac tgtccatacc
    63121 cattctataa caacctctct atccccttac tcccccaact cagcactgta ggcgataatc
    63181 tggtcaactg tgtcagacaa gaattggatg gtatcacgga gtggtttgtc tgttgaaata
    63241 tcagcaccga taatcatggc tgactcaagt ggtgtcttgc taccacctga tttaaggaga
    63301 ttgagccagt cttcagctcc agtttcagaa tgttttagat gaaggtaacc agcagtcgag
    63361 ataactagtc ctgctgagta agtgtaacta tacaagccca tatagtagtg agcttggcgc
    63421 atccaagtca aagctgcatc gtcgtcgatt tcaatggcat cgccccaaaa atctgtcaaa
    63481 acttccttca taatactgtt gagtttgctt gctccgaagg tttctccttc ttcaatcaat
    63541 gtatacacct tacgctggaa ggctgcttcc aagaggtggg tgataaagtt atggaagtag
    63601 gtgtctgtca agcgatgagc cagagcgaag cgtttttgac gtgggtcatt agattggttc
    63661 tctaagtaat cactgagtag caattcattg aaggttgacg gtgcttcaac atagtaggtc
    63721 gacatatggg cattgaagta actttgatga ttgtctgaaa agatgaattg accagaatgc
    63781 ccgatttcat gaatcaaggt atagacatcg ctcaaacggc ctgtccagct catgaggaca
    63841 taagggtgta cgcgatatgg gtccgccgca taaccaccgg aatccttgcc actgttagca
    63901 gcaaagtcca cccagcgctc ttcttggtaa cgagcaactt cctgacaata ttcttgcccc
    63961 aaaggttcta ccgacttcat gaccaaatca taggcatcgt caatagtcac ttcaggattc
    64021 agggcgctgt ccaagtccaa tttccagtct gcaaaggtca tcttttcaag accatttacc
    64081 ttggcaacat gcttgaggta tctctgagcg actggtgcaa agtccttcat gatgaggtca
    64141 atctggcgat caaacatgac acggtccact tcttgttcag ctagaagata atcaaagaca
    64201 gagtcatatc ccttcatatc agccaagagt ttttcagact tgacctgagc cagataggct
    64261 gctgcagccg tattttggtg cttacgaagt ccctctgaga aggaacggaa ggatttctca
    64321 cgaacctcag catcctcgtg attttggtag aaattctcat aggtgacaaa gctgtttttg
    64381 taggtcttgc catgggcttc aaagtcagcc atttcaaaat ccccagctcg catcttagta
    64441 taaatgtcct gcggactata gaaaacttca ccgagattgg tcaaggcctt ctccacatca
    64501 gcccctagat agtgggcttt tttgattttg gcctgacgaa tagctgccgt caagtgaggc
    64561 aattcaccca aacggtccaa gacttcctcg tctgctacca ccaaggcatc gtcaaagaag
    64621 gtcaaggcta cgctggcatc tgtttcaaat tccatcccag cttgggcaat attggcaaat
    64681 tcgtcattgc tatagtccgt cgtctgaggc ataaaagcat agttgccaat atggctcatc
    64741 tgaatgtaga tctgttccaa ttccgcaaag gccttctcga aattctcaaa agtgtgaaga
    64801 ttgcccttgt aatcacggct aaactggttg atgtcttcgc gagctttctc gattgcacgc
    64861 aagaaatcct cacggtcttg gtatagggct gttaagtccc agagttcctt ctctggaaat
    64921 tctgaacggt gtttttgttc cattttcttc ctcttatttc tctaattcta ctaaaacact
    64981 aagggctgat aaggcgtaaa gcggtgctgt ttctgctcgc aaaatacgag gacctaggcc
    65041 taccaaaacg gctcccttag cttcaaaact ttcgatttct gcaggtgaca gaccgccttc
    65101 tggaccaaag ataaagagca gtttggctcc tgtttcaaga ccagtgactg cttgcagaag
    65161 cgcagcggct tctccttctt tagctgattc ttcataggct actatgatag agtcaaactg
    65221 gtccagctga gctagaaaat ctgctttttt ctcgaaaagt ttaatacttg gtacaatatt
    65281 acgcttgctt tgctcggctg ctccaagggc aattttttct agtttttcaa cttttttacc
    65341 caatttcttg ccatcccact tggcaactga ccagtctgca ggaaaggccc agatttggct
    65401 agcacccagt tcggttactt tttgagcgat gaactccagc ttgtctccct tgggaaatcc
    65461 agatgcgatg gtcacttgga ctggtagttc cacattgtca tttaattctt ggaccaactc
    65521 aaactgacga ttttccatat ccagcacgcg cgccaagcgc ttgatgccat catcaaagac
    65581 taaggtaacc tcatcctctt ctttcaagcg cataacctga aacatatgct tactggtttc
    65641 cttgttctcg atagtgacag gagagatagc actgcctttt acaaaatact gctgcatgct
    65701 agcctccaat cacaccagag atatccttgg ttttcttaaa gacacaggca ttccattccc
    65761 cttgaaccat gtgagtttcg aggaaaaatc cagctgattc agccaactcg cgcaccatgt
    65821 cccacttatc cttgataatg ccactcatga tcaggtaacc ttcatcctta accaagcgat
    65881 aagcatcctc tgtcagatga atgaggatat ccgccaagat gtttgccacg atgacatctg
    65941 cttcaatctc cacgccttta agcaaatcgc ctgccgctac atggatattt tccattccag
    66001 ggttgagctc aatattttcc tgagccacac gaactgccac atcatccagg tcataggcga
    66061 aaatttcttt agcccccaga agcgagctgg caatagagag aacccctgaa ccagttccca
    66121 catctagcac cgtttcgcca ccacgaagaa cctgttccaa ggcaaaaagg ctcatcttgg
    66181 tagttgggtg ggttcccgta ccaaaagcca tgccaggatc cagcttgata attttttctc
    66241 ccgcagtcgc ctcatagtct gtccaagagg gaacgatggt caaatcatga gtgatgcgag
    66301 caggttcata gtatttcttc cagttgtctg cccagtcttc ctcagccaag gcagtcgtac
    66361 ctatttttaa ctctcccaaa tccataaaat ctgtcaattc tgctagacga gcctgcaaat
    66421 ccgcctcaac cactgtcaca tccaccgtgt cagggtagta ggctgtcact acgatttctt
    66481 cttgctgctc cacctctggg aaaatctctc caaagcggtc cacatttccc acatagtcca
    66541 tactgtcttc gattgcgact ccttgcgctc ccagctcaat caagagattg gaaaccaact
    66601 cctctccctc acgcttcact gtaactttta actcttgcca tgtttccatt attaatacca
    66661 agcccgtaaa acacaaaacc aaaataggaa attctctgaa gacgcttgtg tctaagagaa
    66721 gtttatcttt ttggcaccgt gtttagggcg ggttcagttt agaaatttaa ccgaaccatc
    66781 ctttctaatc acttactttt aaataatctt ttaatctctc ttgcaactga ggcacaactt
    66841 gactggaact aagaaattcc tcaacattca tcagctgata gccctgtcct tcatctccaa
    66901 atacgatact gtcaaactgg ttctgtgtca actgaccaac tagaaaaacg gactgtttgt
    66961 ctgcaaaaag catacttggg taaaccttac tccaaagcag acaatcttca gtcagatgaa
    67021 tgcccagttc ttcataaact tcacgcgcta cacactcaaa aggactttca tcaccttcac
    67081 gtccaccacc tggcagttcc cacatattgg cccagggaat acttgcctta tcatcgcgta
    67141 agatagtcaa aagcttatcc ccacaaaaca aagcaatctt gcaacctgtg aaatcagaaa
    67201 tttctagttc catcttcagt tccttctaac atttcctttt ccagctcggc taaccagttt
    67261 tcataatatc ttttctcatc cctcaacatt cgactactat ccattttctg tctagcaatc
    67321 ttgagagcct tacgagttcg atctacatct ttcttcacct ttaattgata ccaggcttgt
    67381 atcacttgaa gattggacag tttgagagac agaaacgatt tgacctgtcg aatactagca
    67441 tattgctccg cttgctcaaa atctccttcc aacaaggcga tatgaagcag ggatagttgg
    67501 gcaactgtct gcatcatcgg agtagttgtc ctctcaagta atgcttgaaa ctgctgttta
    67561 gctacttctt ccttcccttc caaaatggaa acttcacctt gcatacctaa tacaccatcc
    67621 gcaaaactcc ctcgtgcatc ctcaggaact gcttgaacaa agtctttcaa atcatattct
    67681 tgaggagcta gcaaggtctg ggcagaatgt ctcaatacca ggtaggcgta tttggtattt
    67741 tcagggtgtt gtagtaattc ccaaattttt gctccatcgg tgatgtcgac tggcaaaatg
    67801 ttatttagga agaaagataa attaagaaaa atccaagtcc ctgcaaaata ccagcttctt
    67861 gtcaaaaatc caaacaatat cgccaataat atcaagccga gatgaaccat caagcctcct
    67921 gaaagcatca ggatgattct ttgatcgctt tcatcctctt ttaaaccaat gtattgagca
    67981 ccaacatttt tcagaatggc tgttctacta agatgaaacc tgcctgactt tttggtcaaa
    68041 ataaaatgtc ctaatccaaa agccaccagc cgatagcctg tcaagtagcc acaaaaagca
    68101 tgacccagct catgaagaat aaagattaaa tacatgctta gaagagcgaa ggcataacca
    68161 aaagtaaagg ctaaaactgc ggaatacccc aactctgcaa atgcgattgt tccacaagca
    68221 aaagctagca taataaagac aacagctagc acataaacca aataagtccc aattttcttc
    68281 ataacacctc caaccaactc ctagtatttt ggataaggat aaaattctcc cttttccaag
    68341 ccaatttttc cttcttcaaa gacttcttgg ttccattcca tgacaaattc ctctgcttct
    68401 gggtcttcca aaaagtccat gaggacatct agcccaacct cagcagtatc tttaaggaaa
    68461 agcgcaaaat aagctaaaaa ttcacgggaa aatccttttt taggcaggta aggaataaca
    68521 gtcaaatagt cttcctcatt gactgttgac ttggcaggat tgtagaaaag gaccgcttcc
    68581 tcaaaaagaa tgtcatctga tgaaacctct ccgtcttcat ccaccatctc cacacctgca
    68641 gcattttgcg cttccaatag aaaactcact tctaccgcat ggttgcgttt gtcccagcta
    68701 atctcaaagt caaagggaaa gttcttgtcc aactcttcct ctaaaatatc taaaaatccg
    68761 tatgttgcca ttttgtcctc tttctatgcg actctttaat cgccccgatt gctcggaaat
    68821 atgctaaaat agatactacc atcttaccac aaaattattt tatgtcctaa ttataccata
    68881 ttacctcatt taaacccttg gtatcagtga ttttcttaaa agtctgattt cttcatttct
    68941 cataaaaatc aatataaaaa gccctcgaaa gggctaataa atctataaaa tcaataggcg
    69001 agtaactagc acaagtggac gtgctttttt attgactatt accacgatac cacgcttaat
    69061 cttaggcttg aactttctta tctgcaatag cgtctgtcaa agtctgagaa aagttaagcc
    69121 ccatttctcg tcccaactta tctgcccatt ttggtatggt caaagtcttt ttaatgggtt
    69181 cctgacttcc taggtattct gatacatcaa cagataccat agaaataaaa gatttatcaa
    69241 ggtcataggt tgacacgaaa tcttcatcat ctttaaaagg atcattatca attaaagaca
    69301 agctattgat atctgatggc tgaggtaact ctccatcact ctctatcaaa tctgcaacag
    69361 ttatccctag ccactccgac cccatagcca aagcctcaga aatcccctct ccttgtgtag
    69421 ctgagtattc aaaatctggg aaatggacaa aataagtcgc ttctgttccg tctgtgtcgt
    69481 cataataaaa taaagctgga tacgtaacta acatttcact acctccatat caaaaagcag
    69541 gggctgaatt ttacaaccca gcttgctttc ttatccctct ttcagtgtac ttattcagct
    69601 caccatgaag gattgtgata ggtctttccc cttgcttttc cattttaata tgggagcctt
    69661 taccgcctct agtctttatc caaccatggg ccgtaaggag tttaaccatc tctttttgtg
    69721 tcataggcat agcgctttta cctcctgaca acaccattat aacacgtgtt acacgtattg
    69781 taaaggagtg atacttatta ttctattata cataaaagcc cctagatgtg gttctaaggg
    69841 aagccaattt attcatacct atttttctaa tgagtagtaa aaactgcttc tttatcgagc
    69901 aattcatcat ctgtatagtc aattgtaaaa gtatctcgat ctaagacaga ttgaggcgga
    69961 gttgaatgaa tcataggaac actgcgtact ctatattttt tatctccaat ttttacaaac
    70021 tgatactctt cgaaaatcaa attcaaacca cgtcaacgtc gccttaccgt actcaagtac
    70081 agcctgcggc tagtttccta gtttgctctt tgattttcat tgagtatgat taactctcaa
    70141 gtcttcgaaa tcaggatttt caacagttat tacaaggagg cgatttacta cttcaaaaac
    70201 atcaattatt ctatttttca tattttttca acccattatt agaatgaact tcttggtaag
    70261 caaaatcaag tttagattta atgttttcgt acaaatctaa aatctctttt ggagtatctt
    70321 cccggaagaa aagttttctt ttccctgaaa taacttgatc actaagaatc caatgacgaa
    70381 tttgttttgt aaaaatcaaa atttcctgac ttggtagttc catcatttcc attgcttatc
    70441 acctctcttt tcattatagt tcatacaatg acattcagca atattatttc tcaagtcagc
    70501 acttccactt ctttaggctc aactatccta ttttgagctt taaggaaaat caaatctctc
    70561 atgctgatac ctctcctcat taaattaaat agtaaaaaag attctatctc actccctgat
    70621 tattacaaaa ccattgaaat atcacaacta ataggctaga atggacatag taagatatag
    70681 tagatgagtc attctactca aatccacgtt agaaaggact gctatgccag acaatctcgc
    70741 gcttcgcatg cgccctaaaa ccatcgacca ggtcatcggt caggagcatc tggtcggacc
    70801 tggaaaaatc atccgccgca tggtggaagc caaccgcctg tcctccatga ttctatatgg
    70861 ccctcctgga atcggcaaaa ccagtattgc ctctgccatc gctggaacga ccaagtatgc
    70921 ctttcgaact ttcaatgcga cagttgatag taaaaagcga ctgcaagaaa tctcggaaga
    70981 agctaaattt tctggtggtc tcgtcctatt actagacgaa attcatcgac tagataagac
    71041 caagcaagac ttcctcttgc ctctcttgga aagtggactg gtcatcatga ttggagcaac
    71101 gactgaaaat cctttcttct ctgtcactcc tgccattcgt agccgagttc aaattttcga
    71161 gttggaacct ctgtctaacc aagacgtcaa agaggccctg cagatagctc taagtaaccc
    71221 tgaacgtggt tttgattttc caatagaact agatgaggat gcgctggatt tcatcgcaac
    71281 ctctacaaac ggagaccttc gctctgcctt taactcactg gacttagctg ttctctctac
    71341 ccctgagaat gacgagggca ttcgccacat caccttagac atcatggaaa atagtcttca
    71401 gagaagctac atcactatgg acaaggatgg agacggtcac tatgatgttc tatctgccct
    71461 gcaaaagtct attcgtggct cagatgtgga tgccagtctc cactatactg cccgcttgat
    71521 tgaggctggg gatctgccta gtctcgctcg tcgcttgact gttatcgcct atgaagatat
    71581 cggcttagcc aatcctgagg cccagattca taccgtgact gctctggatg ctgcccagaa
    71641 gattgggttc ccagaagccc gcattctcat tgccaatgtc gtgattgatt tggccctttc
    71701 tccaaaatcc aactcagcct atgtagctat ggataaggca cttgctgacc tcaaaacatc
    71761 agggcacttg cctattccgc gacacctgcg tgatgggcac tacagtggaa gcaaggaact
    71821 ggggaatgcc caagactatc tctatccaca caactatcct ggaaattgga tcaagcaaga
    71881 ctatctgcca gaaaaaattc gtaatcatca ctatttccaa gcagaagata ctggtaaata
    71941 tgaacgggct ttggctcaaa gaaaggaagc tatcgatcgt ttgcgaaaaa tctgaaatcc
    72001 ttttcaaaaa attgcacttt cctcttgatt ttttttgaaa aagtggtatc atataagtat
    72061 agaaacgctg tggtgtacga cttcacactt aagtgttgac cgactatttt ttgtattatt
    72121 agggaaacaa aagtcttcta acagcatgta ggccgtctca cacggaaaca gcttcagtta
    72181 gagcgagttg cccacctgct taattgcgcg ggttcaatac aaaccgtgaa gtttcggcac
    72241 caatacagct tttttctttg cctccttagc tcagctggca gagcagcgga ctcttaatcc
    72301 gtgggtcaca ggttcgatcc ctgtaggggg catctacata caacaggaaa agccttggaa
    72361 ccaaggtttt tttgcttaaa taaaattttt ttcaaattct ttagaaaact agcttaaatc
    72421 ataatccaac accaatttta caaataccat aaactaagct tatataccca aaacacaaaa
    72481 agtcctcttt ccactatttt agaaagagaa ctttttcttt aggagaaata acttaatttt
    72541 taatcaattc gtgatagctc agctggcacc gttaagtaat aagttgcagt caagcttgct
    72601 tcaccttgat tgacaaaaat ctcgatggaa tttttatcta gaacaacttc caattcttta
    72661 gcttcaatat ctacataccg tcgactagtg tcctgttctt cttcacctag aattttttga
    72721 ataagatggc tacgatcaat gtaaacttgc tgcgcattac tgtcataacc aaattcaaga
    72781 taatctgtat catttcctaa gtggtaatga caatctttat ctatttggat ttgatattgg
    72841 ccttttttaa cagggaattg tcttagtttg ccatcttcca atcttagaat tctaggtaaa
    72901 gtcatagcac atgcccattt gtgttcttgg tcatgggttg gaagggtacg cccccatgtc
    72961 tgcatccaag caatcaggat acgacgattt tgatcgtcca acaatgtttg aggcgcatag
    73021 aagtcttggc catgatcaat ttcttgaact gattctggga taaaacgttt ttctctccaa
    73081 tctaccttac ccgtgaacaa aagcgatgag ttgatgttat gatatgagtc tccctcacgc
    73141 tgataacgca tgggtgacat aataaggcaa tctttcccat ctaactcgaa gtaatctggg
    73201 cattcccaca taaagccttg gtgttctccc ccttttaaaa agatggattc gaactgccat
    73261 tctactaggt tatcggaccc tagtagaacg atacagccca cattatcctt gtgtttggca
    73321 gctactacgg agtaatagcg tccatctttt tcaaagagtt ttggatcacg gaaatcagca
    73381 gcaatcaact catctggcaa gtctgatcca gttgcaactg gattttggga aatcttttca
    73441 aagtgaatcc cgtcatctga aaatgccata ttttgcactt ggcggacacc ggttttttct
    73501 tcgatatgcc cagtgtacat gagccagagg cgatcatcct tgacaatggc agagcctgag
    73561 aaacaaccat ttcggtcata atcttgatca ggagcaagtg ccactggcaa gtgctcccaa
    73621 gtcaccaagt ccttactttt agcatgtccc cagtgcatag gtccccaaac actatcatat
    73681 ggatagaatt gataaaagag atggtattct ccacgaaaat agacaaatcc atttggatca
    73741 ttgatccaac caatctcagc tgaaaaatgt tcttcaggct tatattgagt attaacgaga
    73801 tgtttatttt ctgctataaa acgattggct ttttctactg tgtatttctt atctcccata
    73861 atcaacctct agtttttgtt tgcttggtat tggtcgtagt atttttgttt aatagcgagg
    73921 taattagaaa gtccgtattt ttcaagttct ttcttgtaat catcccactc agtatcaata
    73981 ttgccattta caatccattc agcacgttta cggtagatat agtcattcat atctgcttcg
    74041 atatgggcaa ttttgtccaa atcttcctgt gtcataaaga ctcttggata gttattgtca
    74101 ttgctcatgt aaggaacata atattctttg ataagatcca aacgccattt ggcatcatca
    74161 ggtatggttg ttactttacc atagtatgaa tctaggatag ctagtggtcc tcctacttca
    74221 gtcttttgac gaagttctgc tggtgcagtt ccgtttagtg gtaagtgttt tagactattt
    74281 gacgcttgat ccaattcaaa gatgttttgt tgtttgtcat ctccgtaagt tccccagtta
    74341 ttttgcacag attggagtgg agcgtattgt gcatcaatcc atttagctgt caattctagg
    74401 tttttgttta cactggtaat aaccatcttg tcacgtgcaa atcccatacc gtttgtacga
    74461 gctacgtgtt tttgaccact tggtccagca agtactggta aaacatcata actttcgtta
    74521 cttccagtaa cattattctt atcccatgta aagtaaacac caaatttctg atcatgacct
    74581 ttagcaatgt aactattcca atcatgttcg aaagcttctt tatcaatcaa gcctttttct
    74641 tgcaattgac ggataaattt gacaccttct ttatagttat cgttatctgc tgtgaagtca
    74701 actttgccat catttcctac tactaaatga tcatcgttat cccctatacc aaatgcagca
    74761 aataggaatt taaaatcttc gtttccgtta ccactaataa atgaaaatgg aatttcatca
    74821 gcctctccat ttccatttgg atccccgttt ttgaaagctt ctaggacttt aatcaaatca
    74881 tcagtagctt ttggcatttc aagaccaagt ttcttaagcc aatctttgtt aatccaagcc
    74941 atatcgttga cgctgtgaat agactcttta ccatctccaa gctcttcaat ccatgggaat
    75001 gagtaaatgt gcccatcagg tgctgtcatc aaggccttgt actctggttt ctcatccaaa
    75061 attttcttaa gatttggcat gtatttatca atcaaatctt caactggaat aataacacct
    75121 tttttagccc agttcatcaa gtccacatct gaagctccgt cgttgtggat agcatctggt
    75181 aaatcaccac tagaaatatc caagttacgt ttttctgcaa agtcggattg gtagttggtc
    75241 cagtcaatat gaacgccagt ttccttctcc aaacgttgca aaattaactt ttcatttggg
    75301 tctttaggag ataacggtga actggctgtc ataaacttca atgttttctt ttcttgaagc
    75361 gggaatgtta caccttccaa cttataatct ggacttgaag ctgtattttt tgagccacag
    75421 gctgcaagta ctgctaaact agctgtcaac aaaactgctg attttgagaa tgttttgaat
    75481 ttcatgagaa aactcctttt attttttctt tttttatcct ttaagtgaac cagccataat
    75541 tcctttatca aagtattttt ggaagaatgg atacataaca atcaatggca agctggaaat
    75601 gacaatagtt gcgtatttaa tcaattcagc taaacgtttc atttcattca tagccgcttg
    75661 tgctccaatc atgtcttgac ctggttggct ctgaatgaga attttacgaa gtacaagttg
    75721 caatggttcc aagtttggat ccttgatata aatcattgca tcaaagtatg agttccactg
    75781 tcctacaaaa gcataaagga agagaacaaa cataattggt tttgcaagag gaagcatgat
    75841 tttgaagaaa atctgtaaat catttgcacc atcaatgaca gcagcttcaa ctaattcttc
    75901 aggcaatcct tggaaatagg ccctagcaag aataatattc caaacgttga cagcacctgg
    75961 aacaatgata gcccatggag tattgagcat tcccaattct tttacgagca agtaagttgg
    76021 gactaaacca ccaccaaaga acatagtcac aatcaagaag tagttaatcc aacggcgccc
    76081 taccaaatct tttttggaaa gaggataagc tgtaaacaca gatagcaaga ctgttaaagc
    76141 tgcaaatcca aaagagtata gtagagaatt gataaaacct cttagaatag attggtcact
    76201 gaatacacgc tggtaacctt ctacagtcca atcggctgga ttaaagctaa tccctctact
    76261 aaccagaacc ttaggatcca taaaggatgc tacgacgata taaagtaaag gaagcaaagt
    76321 catcaaaacg ataaagacaa taatgatttt atttaagagt aagatacgtc tatcaaattt
    76381 tgtatccata atcgaatttt tcatactttc ctccttaaat tccttcacca ttattcatgc
    76441 gtttaacgat ttggttaact gcaacaagca atactacgtt aatcactgca ttaaacaaac
    76501 caaccgctgt tgagtaagaa tagtctcctg atacaagacc aactttatag tcatatgtcg
    76561 agataatttc agaagttggc aaatttaacg atgtctgcat caagaatgct ttttcatatc
    76621 cgacattcat aattccacct gcagctaaaa caaattggat aaccataata ggcttaagag
    76681 ctggaatatc aatgtgccag attcgttgga agatattggc tccatccagt cgggctgctt
    76741 ctactaaggc tggatctaca tttaccaatg ttgccgtgta gagcgttgaa gcccagccca
    76801 ttccttgcca gataccacta aagatgtata aaggtctaaa gaagtctgga tttgtcaaga
    76861 agtcagcctt cattccaaac atagaaagaa aattgttgat tggtcctccc actgaaaaga
    76921 agaggaaaat cataccgaca ataacaacga ctgagataaa gtttggtgcg tataaaatga
    76981 gctgaattcg ttttttgact ttttcactca agagttgatt gagcataata gcaagaatga
    77041 ttggtggtaa aaagccaagc aataaaccat agatacttaa ttttaatgtg ttggctaaca
    77101 agataccaaa gttgggagag gatatgaatt ttgtaaactc agaaaaacca atccaatcac
    77161 tccctaaaat tccttttaaa ggattgtaat ctttaaatgc aattaaaacc ccatacatag
    77221 ggatgtattt aaagataaag gttaaaacta aaccagggac agtcatcaat aacaagagtt
    77281 tttgtttctt gattctttcc caaagagaaa cttgcttcgc tttgctattc atagcaacct
    77341 cctttttgaa acgtttcatt tttttctaga aaagatagcg cttggcgctg tctctttatt
    77401 tctttttttg aaacgtttca tttttgtttt aaaaataaat ctttttatct gaattcattc
    77461 tatcattgat agcgctttct gtcaagactt attttcattt tttgttgttt ttccttcaac
    77521 aaattttact ggtaggattg tctgcaaatt aacagtcttt ccatcaatta tatcaaacaa
    77581 aatacgaacc gcttcttttg ccatttcttc caatggttgt tcaatagttg aaagtagata
    77641 atctctatct ccagccattt taattccatc gtatccaata atttggacat catgaggaat
    77701 acgtttgcca tttttttcta gtatttcaat cacatccaaa gctgtaaaat cgttgattgt
    77761 aaaaattcca tctatagaag aattttcttc caagaaactc tctagctttc cataatagtc
    77821 agtaactgtc tcatccaaat caaaaatact aagaggtatt ttatgctctt ggacatactt
    77881 ttcaaatgaa attctacgac gtttggtttc attaatggtt gtattatgtc cgcccacaaa
    77941 ggctaaatgc tgacatcctt tactaattaa ttgtttagct gcttctcttc cacctgcatc
    78001 attatctgat gaaacacaag gaatggcaat atctgagtat gtgcggtcaa tactaacaaa
    78061 gggaattcct gacgtcaagt aatgttcaat tggactatag gtaatggcaa ccactccatc
    78121 aactttatta tgacgcaaca tctccagata gtcttgctct ctatttgtac cattgataga
    78181 acataagagt aatttgttat ttctcttata gacttcattt tccacatgca tagcaaattc
    78241 tgaaaagaag ggatgccaga tacttggtac aatgattgca atcgtttctg ttcgattttt
    78301 tttcattcct ctagcgtagt aatctggaat gtaattcaaa gttttaatcg cttgttccac
    78361 ttttttcaaa gttacttctt taatgccttt ttctttatta attacacgtg aaacagttcc
    78421 aacactaact cctgcttcta aagcaacatc tttcatggta attgattttc tttgttctac
    78481 catattatca cctcctttca atatatagta tcatgcaaat gctttttaag caactatttc
    78541 tcaatcattt ttggccagat catttatccc atcatgaata aaatcactcc aattagcttt
    78601 tgaaaatact tcaattttca tgtgtaaaca tctacataaa acaggaaaag ccttggtttt
    78661 atggcttttt tcgtatcttc tacaaaaaaa gcaagagttt tagagggcta taaatctaga
    78721 tgtacatttt gcttaaatga ttgaaggtct tttcttaaca aaaacacccc aaaaattaga
    78781 ttttttctgt ctaacttttg aggtacagtt caaacgcgaa atagcgtttt ttgttatttt
    78841 tggttactca tctaatcgaa taaacatcat ggcatttaac aaatatatga gtgagaccgt
    78901 gtttatatta tttgaataga tgagtctctt attttcaata ggaggaataa taaaattaga
    78961 aataatgata tcataaggtg aatcttctaa agattccttt gataattcta attcagtcca
    79021 aacttccagt tcaaaattat tgctacagta ataagaaagt gtctctgcaa cgaattttgc
    79081 atgatactga tcaaaattac tcataaccaa aacctttagt ttaggctgat tttgtagcaa
    79141 attaatcacc aaatgtttgg tatgagtgat gaaggtataa gatagatgat ttaccatcat
    79201 tgaactagaa caaacctcaa gagtctctaa atagtgagaa agctcttttt ttatatctga
    79261 aacaaatttt ggaaaaatat tttgaaagtt cctgattgta ttcccttttt gatcaaataa
    79321 aataaactca gtaaacaact cttgacgata cagatgtgcg gtattatgca gatgccaaat
    79381 cagattatcc ttattctcca tttcaatctg atacttgact gaaatctgat caataaaatc
    79441 actcaataga tggtaagatt tttcaacata actatccttt tttacgcatt tcataaagag
    79501 actttcatct atgaaaaaca ttttttgaaa gtaagacaca aataattggc aaacaacttc
    79561 ttcatctaaa gagatattgt attctgattc aaaactctga gcaacacctt ctattccttc
    79621 tgcctgcatt aaaaaatcca aactttggtc gttaaaagaa tctttatcta cttccataaa
    79681 atgaccaaac tttattctat ataggttcgt aactaggagc aactttagca ttctatgcgt
    79741 tgacaaattc attggaaagc ttgtttcctt ataaaccaat tctaacaatt gagatagtgg
    79801 ctctgatgaa aaattttcaa atggccattc taggaaataa tatttttctg aaaaatattg
    79861 tgcaaaaaag taacgaatgt ctctctcatt tccaatgatt tgaacagggg tcaaactgac
    79921 ttcaaattga aattgccttt taatcacttt attgatttgg ctaataatac gatagagcga
    79981 agatgaactg atataaaatt ctttacaaat actctcagct tgacaacctt cattaaagaa
    80041 gatgaattct aaaatcgaaa aatgagttga atgtttaaag aaatgatggt aaaccatttc
    80101 aatatcacta tcatcggtat taataatgcg tataccatta gtagaagaat gaaaaatcaa
    80161 gtcaggaaaa gcagatttaa catgggatag atcatctttg actgcacgtt ctgtacaatt
    80221 taataactct gctagttcag aacgatgaaa ccaacgttta tgttcaaata ataattctaa
    80281 taattctaat tgcctatgac tttttttaga taataaatct ctcatgaata tctttctctc
    80341 tttataaatt atcggattaa acctcttgca attataccac aaagaatagg tatagcatga
    80401 tataacgact tttcctaaaa tcttttattt cgtataataa cactacggag acaatatata
    80461 aacaattttc ttattttacc gtctattgag ggcgtgaata ca
//
LOCUS       DBERDS010000004        78650 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.004, whole genome shotgun sequence.
ACCESSION   DBERDS010000004 DBERDS010000000
VERSION     DBERDS010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 78650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.004"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..320)
                     /locus_tag="ACL73E_000289"
     CDS             complement(<1..320)
                     /locus_tag="ACL73E_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800333.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKN"
     gene            complement(416..1126)
                     /locus_tag="ACL73E_000290"
     CDS             complement(416..1126)
                     /locus_tag="ACL73E_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGS0800334.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(1129..2820)
                     /locus_tag="ACL73E_000291"
     CDS             complement(1129..2820)
                     /locus_tag="ACL73E_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800335.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(2832..3842)
                     /locus_tag="ACL73E_000292"
     CDS             complement(2832..3842)
                     /locus_tag="ACL73E_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800336.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(3945..5012)
                     /locus_tag="ACL73E_000293"
     CDS             complement(3945..5012)
                     /locus_tag="ACL73E_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0800337.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(5037..5696)
                     /locus_tag="ACL73E_000294"
     CDS             complement(5037..5696)
                     /locus_tag="ACL73E_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGS0800338.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(5906..6886)
                     /gene="galE"
                     /locus_tag="ACL73E_000295"
     CDS             complement(5906..6886)
                     /gene="galE"
                     /locus_tag="ACL73E_000295"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS0800339.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            complement(6899..8374)
                     /gene="galT"
                     /locus_tag="ACL73E_000296"
     CDS             complement(6899..8374)
                     /gene="galT"
                     /locus_tag="ACL73E_000296"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS0800340.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            complement(8387..9028)
                     /locus_tag="ACL73E_000297"
     CDS             complement(8387..9028)
                     /locus_tag="ACL73E_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGS0800341.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QIIQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            complement(9086..9469)
                     /locus_tag="ACL73E_000298"
     CDS             complement(9086..9469)
                     /locus_tag="ACL73E_000298"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800342.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDPIGTNSVLNKKIILQKIR
                     KLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELIK
                     MRFNSSAIDPIYGKKDDASIVVIDV"
     gene            complement(9641..9937)
                     /locus_tag="ACL73E_000299"
     CDS             complement(9641..9937)
                     /locus_tag="ACL73E_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800343.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(9921..12080)
                     /gene="pfbA"
                     /locus_tag="ACL73E_000300"
     CDS             complement(9921..12080)
                     /gene="pfbA"
                     /locus_tag="ACL73E_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGS0800344.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(13211..14437)
                     /locus_tag="ACL73E_000301"
     CDS             complement(13211..14437)
                     /locus_tag="ACL73E_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGS0800345.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(14480..15172)
                     /locus_tag="ACL73E_000302"
     CDS             complement(14480..15172)
                     /locus_tag="ACL73E_000302"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS0800346.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(15345..17096)
                     /locus_tag="ACL73E_000303"
     CDS             complement(15345..17096)
                     /locus_tag="ACL73E_000303"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800347.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(17086..18831)
                     /locus_tag="ACL73E_000304"
     CDS             complement(17086..18831)
                     /locus_tag="ACL73E_000304"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800348.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(18959..19489)
                     /locus_tag="ACL73E_000305"
     CDS             complement(18959..19489)
                     /locus_tag="ACL73E_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGS0800349.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(19486..19942)
                     /locus_tag="ACL73E_000306"
                     /pseudo
     CDS             complement(19486..19942)
                     /locus_tag="ACL73E_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            20076..20903
                     /locus_tag="ACL73E_000307"
     CDS             20076..20903
                     /locus_tag="ACL73E_000307"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGS0800350.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            20915..21166
                     /locus_tag="ACL73E_000308"
     CDS             20915..21166
                     /locus_tag="ACL73E_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0800351.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLSL
                     EECQLMLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLY"
     gene            21173..21301
                     /locus_tag="ACL73E_000309"
     CDS             21173..21301
                     /locus_tag="ACL73E_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HGS0800352.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPNGYFLRFSE"
     regulatory      21684..21779
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            22179..22760
                     /locus_tag="ACL73E_000310"
     CDS             22179..22760
                     /locus_tag="ACL73E_000310"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGS0800353.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTTQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            22760..24022
                     /locus_tag="ACL73E_000311"
     CDS             22760..24022
                     /locus_tag="ACL73E_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGS0800354.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(24109..24975)
                     /locus_tag="ACL73E_000312"
     CDS             complement(24109..24975)
                     /locus_tag="ACL73E_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HGS0800355.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(24962..25732)
                     /locus_tag="ACL73E_000313"
     CDS             complement(24962..25732)
                     /locus_tag="ACL73E_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGS0800356.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(25758..26612)
                     /locus_tag="ACL73E_000314"
     CDS             complement(25758..26612)
                     /locus_tag="ACL73E_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HGS0800357.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(26769..27173)
                     /locus_tag="ACL73E_000315"
     CDS             complement(26769..27173)
                     /locus_tag="ACL73E_000315"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGS0800358.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEDRQVRI"
     gene            complement(27243..28724)
                     /locus_tag="ACL73E_000316"
     CDS             complement(27243..28724)
                     /locus_tag="ACL73E_000316"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGS0800359.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(28743..29921)
                     /locus_tag="ACL73E_000317"
     CDS             complement(28743..29921)
                     /locus_tag="ACL73E_000317"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGS0800360.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            30086..31093
                     /gene="galR"
                     /locus_tag="ACL73E_000318"
     CDS             30086..31093
                     /gene="galR"
                     /locus_tag="ACL73E_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGS0800361.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(31139..32176)
                     /locus_tag="ACL73E_000319"
     CDS             complement(31139..32176)
                     /locus_tag="ACL73E_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGS0800362.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(32177..32530)
                     /gene="nmlR"
                     /locus_tag="ACL73E_000320"
     CDS             complement(32177..32530)
                     /gene="nmlR"
                     /locus_tag="ACL73E_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGS0800363.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(32774..33664)
                     /gene="czcD"
                     /locus_tag="ACL73E_000321"
     CDS             complement(32774..33664)
                     /gene="czcD"
                     /locus_tag="ACL73E_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGS0800364.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            33797..34333
                     /gene="sczA"
                     /locus_tag="ACL73E_000322"
     CDS             33797..34333
                     /gene="sczA"
                     /locus_tag="ACL73E_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGS0800365.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(34500..35306)
                     /gene="pnuC"
                     /locus_tag="ACL73E_000323"
     CDS             complement(34500..35306)
                     /gene="pnuC"
                     /locus_tag="ACL73E_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGS0800366.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(35651..37171)
                     /locus_tag="ACL73E_000324"
     CDS             complement(35651..37171)
                     /locus_tag="ACL73E_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGS0800367.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(37164..37892)
                     /locus_tag="ACL73E_000325"
     CDS             complement(37164..37892)
                     /locus_tag="ACL73E_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0800368.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(37907..38671)
                     /locus_tag="ACL73E_000326"
     CDS             complement(37907..38671)
                     /locus_tag="ACL73E_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGS0800369.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(38675..39118)
                     /locus_tag="ACL73E_000327"
     CDS             complement(38675..39118)
                     /locus_tag="ACL73E_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGS0800370.1"
                     /translation="MRDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(39800..40096)
                     /locus_tag="ACL73E_000328"
     CDS             complement(39800..40096)
                     /locus_tag="ACL73E_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS0800371.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLASFIKREESKYRGTATSALMYEELFKML"
     gene            complement(40118..41182)
                     /gene="pepA"
                     /locus_tag="ACL73E_000329"
     CDS             complement(40118..41182)
                     /gene="pepA"
                     /locus_tag="ACL73E_000329"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGS0800372.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            41582..42283
                     /locus_tag="ACL73E_000330"
     CDS             41582..42283
                     /locus_tag="ACL73E_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGS0800373.1"
                     /translation="MTKTILVTGETGYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKSYLEENQIDAALHCAGETVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            42299..42409
                     /locus_tag="ACL73E_000331"
     CDS             42299..42409
                     /locus_tag="ACL73E_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGS0800374.1"
                     /translation="MNYLFQEDSSSQIFNLETKKGYTIKEIFKTAEELLN"
     gene            42706..43665
                     /locus_tag="ACL73E_000332"
     CDS             42706..43665
                     /locus_tag="ACL73E_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800375.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            43655..44611
                     /locus_tag="ACL73E_000333"
     CDS             43655..44611
                     /locus_tag="ACL73E_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGS0800376.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            44608..45360
                     /locus_tag="ACL73E_000334"
     CDS             44608..45360
                     /locus_tag="ACL73E_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800377.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            45456..46421
                     /locus_tag="ACL73E_000335"
     CDS             45456..46421
                     /locus_tag="ACL73E_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0800378.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIIGMPTKTIPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSIKANIES
                     LASAFGETSIQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(46646..46888)
                     /gene="yidD"
                     /locus_tag="ACL73E_000336"
     CDS             complement(46646..46888)
                     /gene="yidD"
                     /locus_tag="ACL73E_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGS0800379.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(46888..47610)
                     /locus_tag="ACL73E_000337"
     CDS             complement(46888..47610)
                     /locus_tag="ACL73E_000337"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS0800380.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(47597..48166)
                     /gene="scpB"
                     /locus_tag="ACL73E_000338"
     CDS             complement(47597..48166)
                     /gene="scpB"
                     /locus_tag="ACL73E_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGS0800381.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(48185..48913)
                     /locus_tag="ACL73E_000339"
     CDS             complement(48185..48913)
                     /locus_tag="ACL73E_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGS0800382.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(48913..49647)
                     /gene="xerD"
                     /locus_tag="ACL73E_000340"
     CDS             complement(48913..49647)
                     /gene="xerD"
                     /locus_tag="ACL73E_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGS0800383.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(49644..50105)
                     /gene="cbpB"
                     /locus_tag="ACL73E_000341"
     CDS             complement(49644..50105)
                     /gene="cbpB"
                     /locus_tag="ACL73E_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGS0800384.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(50102..50623)
                     /locus_tag="ACL73E_000342"
     CDS             complement(50102..50623)
                     /locus_tag="ACL73E_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS0800385.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(50599..51570)
                     /locus_tag="ACL73E_000343"
     CDS             complement(50599..51570)
                     /locus_tag="ACL73E_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGS0800386.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(51567..52361)
                     /gene="racE"
                     /locus_tag="ACL73E_000344"
     CDS             complement(51567..52361)
                     /gene="racE"
                     /locus_tag="ACL73E_000344"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGS0800387.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(52568..52816)
                     /locus_tag="ACL73E_000345"
     CDS             complement(52568..52816)
                     /locus_tag="ACL73E_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGS0800388.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(53072..54697)
                     /gene="treC"
                     /locus_tag="ACL73E_000346"
     CDS             complement(53072..54697)
                     /gene="treC"
                     /locus_tag="ACL73E_000346"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGS0800389.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(54875..56842)
                     /gene="treP"
                     /locus_tag="ACL73E_000347"
     CDS             complement(54875..56842)
                     /gene="treP"
                     /locus_tag="ACL73E_000347"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGS0800390.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLRDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEATKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQVQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            57027..57737
                     /gene="treR"
                     /locus_tag="ACL73E_000348"
     CDS             57027..57737
                     /gene="treR"
                     /locus_tag="ACL73E_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGS0800391.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYIVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(57770..58573)
                     /locus_tag="ACL73E_000349"
     CDS             complement(57770..58573)
                     /locus_tag="ACL73E_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800392.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(58586..59463)
                     /locus_tag="ACL73E_000350"
                     /pseudo
     CDS             complement(58586..59463)
                     /locus_tag="ACL73E_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(59475..60412)
                     /locus_tag="ACL73E_000351"
                     /pseudo
     CDS             complement(59475..60412)
                     /locus_tag="ACL73E_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(60903..61829)
                     /locus_tag="ACL73E_000352"
     CDS             complement(60903..61829)
                     /locus_tag="ACL73E_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0800393.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(61840..62907)
                     /locus_tag="ACL73E_000353"
     CDS             complement(61840..62907)
                     /locus_tag="ACL73E_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800394.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYAPCHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(62916..63842)
                     /gene="oppC"
                     /locus_tag="ACL73E_000354"
     CDS             complement(62916..63842)
                     /gene="oppC"
                     /locus_tag="ACL73E_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGS0800395.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(63842..65338)
                     /locus_tag="ACL73E_000355"
     CDS             complement(63842..65338)
                     /locus_tag="ACL73E_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800396.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(65405..67384)
                     /locus_tag="ACL73E_000356"
     CDS             complement(65405..67384)
                     /locus_tag="ACL73E_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0800397.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(68070..69263)
                     /locus_tag="ACL73E_000357"
     CDS             complement(68070..69263)
                     /locus_tag="ACL73E_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGS0800398.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(69401..70843)
                     /gene="gtfA"
                     /locus_tag="ACL73E_000358"
     CDS             complement(69401..70843)
                     /gene="gtfA"
                     /locus_tag="ACL73E_000358"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGS0800399.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            complement(71154..71987)
                     /locus_tag="ACL73E_000359"
     CDS             complement(71154..71987)
                     /locus_tag="ACL73E_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0800400.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(72001..72867)
                     /locus_tag="ACL73E_000360"
     CDS             complement(72001..72867)
                     /locus_tag="ACL73E_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0800401.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIVMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(72881..74139)
                     /locus_tag="ACL73E_000361"
                     /pseudo
     CDS             complement(72881..74139)
                     /locus_tag="ACL73E_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(74174..76336)
                     /locus_tag="ACL73E_000362"
     CDS             complement(74174..76336)
                     /locus_tag="ACL73E_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGS0800402.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQIEKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYENQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            76444..77304
                     /locus_tag="ACL73E_000363"
     CDS             76444..77304
                     /locus_tag="ACL73E_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS0800403.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHMGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            77301..78236
                     /gene="birA"
                     /locus_tag="ACL73E_000364"
     CDS             77301..78236
                     /gene="birA"
                     /locus_tag="ACL73E_000364"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGS0800404.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(78362..78449)
                     /locus_tag="ACL73E_000365"
     tRNA            complement(78362..78449)
                     /locus_tag="ACL73E_000365"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(78413..78415),aa:Ser,seq:gct)
     gene            complement(78456..78529)
                     /locus_tag="ACL73E_000366"
     tRNA            complement(78456..78529)
                     /locus_tag="ACL73E_000366"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(78493..78495),aa:Ile,seq:gat)
     gene            complement(78565..78635)
                     /locus_tag="ACL73E_000367"
     tRNA            complement(78565..78635)
                     /locus_tag="ACL73E_000367"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(78601..78603),aa:Gly,seq:tcc)
BASE COUNT        23908 a        17236 c        13868 g        23638 t
ORIGIN      
        1 ttatttttaa gaatgtttcc aacttcacga caaataaatt catatgagaa aaaactgcca
       61 taaaattgta gattaacttt ttcagtaaaa tgtgtaggat ttataaaaac atataatagc
      121 ctgtcaatgt aacattttaa catagagtta attttttctt taaagataac atttgttatc
      181 aactcatcag gaggtaaatg aaaggcaaac accatttcac aaatatcata aaaagaaata
      241 aatttgtata cttgtatcaa acaattatta tcaaaatatt ctattttacc taaatcaaaa
      301 ttgattttat aatctttcat aaaaacctct gagcaaaaat ctactcaaaa attagatgat
      361 taaaacatct aaaaaacaaa aggacaaaaa catctgtccc tttgtttact aaatttcagc
      421 taatttcttc gacataaata acacctacaa tattagcaat ttcttccatc agtcgaagat
      481 gttcaaatct acctgataat tccagagtaa taaatgacgc tattttttta tctggaacat
      541 caaagtattc aattctgtca gaattaacat ctccaaacgc tgttcttgaa tcggtcattc
      601 tgataccatt ttctgcacaa taaaccaata cacgattata ggcttctgta gatttaacca
      661 ctatatacaa ttcaatcatt ttagaacgat tttgtagata tttttttagt ggttggaaca
      721 tggatatcac accccaaaca gaaatggcta ctaaaagagc tccctcataa aaacctactc
      781 caatagctaa tccaattcct gccgaagccc aaatgcctgc tgcagttgtc agacctgtaa
      841 ttttcttttt atctgtaata agaatcgttc cagcgcctag aaaacccaca cctgatataa
      901 cttgagctcc taatcgtgta ggatctcctg tcccaaattt ataagatacg tattcattcg
      961 tcatcataat caaacatgca gctagacaaa caatactata agttcggatg cctgcaggct
     1021 gggatttgct ccctctctct aaaccaatta tactaccaat gactactgat aaaacaatcc
     1081 tgacaactat ttcaatattt gataacccaa gactagtggc tgtcatgatt atttccttac
     1141 tttacgcccc ggtctttgtg tgaagtataa taccgttcca gaaataatca tcagaacaat
     1201 tgtataaaca aataccagag cttgtgcatt agatgttgct gtttcatcac ctgcagatcg
     1261 aatcgtaata cctaatggtt gagctagggg atggtaaagg aatacagata agtcgaagtc
     1321 agttaataaa gagttaaagt ttaaagcaat aacagagaga acaaccggta aaataaatgg
     1381 aatgataacc ttcatcatag tataaaaagg tgaagcaccc atacttcttg ctgcatcttc
     1441 catctcatca tcaacactaa ataaaatagc acgtaccatt ctataagaaa atgggatttt
     1501 tacaactata tatgcaataa gtagaattac caaactacct accaaaatct gattcaagac
     1561 aagaaattgt ggctgattaa aagtaaataa taaacttact gctaaaagcg tacttggtaa
     1621 taaccaagga agtagagcac catattcaaa taagaaatca aaacgagatt tatgttttct
     1681 gacaacacga gcaaatacaa ctgcgagaat tgttgctgtt gtcgcagcaa taatagaata
     1741 aataaagctg accaagaatg gagagaatgc cgcactatta ctaaagaata agcgataatt
     1801 ttctaaagta aagtttgata atgttaagtt acctgtttga attgcaactg gatctgtaaa
     1861 tgagtataat actataaaaa ttagtggaag catgaaaact gtgaacaatc catatgctac
     1921 aatgtgagca atgatattcc aaggcttaga cgcaattttt tgttttttaa gaggcgcttt
     1981 agtcttagag atagaaatat aatttccacc tttttctatc ttattcatga tagtaagcaa
     2041 aattgtagtt gcaataccta aaataattgc aagtaaggca gctaaatcac gagaattccc
     2101 catccctgca aatgtaataa tcattggatt tatagtttga aattctttac caccaacaat
     2161 catgggtgct gctactgcag ataaaccact aagaaaaacc ataatagtaa gtgcaaatag
     2221 agttggaatt aaggttggta acactacttt tcggaaaaca gtaaatggtt ttgctcccat
     2281 atttcgagca gcctcaatag tgtgatagtc aacgcttcga attgtatttg ttaaaaacaa
     2341 tgtatgatta gcagttcctg aaaatgtcat aatgaataag actgcaccat acccaataaa
     2401 ccagttaggg tctaaagaag ggataacatt ttgtaaaaat tttgtaatca atccatatgg
     2461 accatagaca aatttatatc cagtcgctaa aaccactcct ccataaatta aagaggtcat
     2521 ataacctaat tttaaaattt tagcaccttt aatatcaaag tactctgtaa atagaacaca
     2581 aagaatacct acgacattaa ctgtaataat gagtgaaaat gctaacttaa aactgttcat
     2641 aatactctga agtgccctct gagattttag aacacgatgt acagcatcaa gggaaaattc
     2701 tcctcctttt acaaatacat tcactactag atcaaagttt ggataaataa taaatgttac
     2761 taagaaccag attaacccta aacgaataag ccaatctttt aaatttaatt tatgacgcat
     2821 actgcacctc cttaaaattg cagaacgtct gatggtgtga taaataattc cacactttct
     2881 ccgacagatc taatagcagc ctgactatca atacttgtta cattaagaat ctgactttca
     2941 gaaactttta ttgtatagtg aattgtaact ccagaaaact caacatcaat aattgtccct
     3001 tttagaatga aatcttgttc agtttcacga ttgaatcgaa ctttctctaa tcgaatgtat
     3061 ccttttttat cttctaagaa aacgcttgta tttttcagta atacttcgtg gactgtttca
     3121 tcggtcaaaa cattaatatc tccaataaaa tcacatacaa attcagtttg agaattatga
     3181 taaatctcta ctggtgtacc gacctgttcg atgtatccat tgttaaagac tgcaattcta
     3241 tcagataaag tcaaggcttc ctcttgatca tgagtaacat ataaagtagt aatacctaac
     3301 tctttttgaa gtcttttcaa ctcttttctc aaatctacac gtaattttgc gtcaaggttt
     3361 gacaatggtt catctagaca aagaatttta ggttcaagaa ccagagcacg agccaatgct
     3421 accctttgtt gttgaccccc agataattct gatacattac gctgtaactg ttgatcagag
     3481 atcttaattt ttgctgccac tgctgatact ttagctttaa taacatctgg agctaccttc
     3541 ttaactttta aaccaaatgc aatattatca aaaacagtca tagttggaaa tagcgcataa
     3601 gattgaaata caataccaat tccacgcttt tcaggttcca aatgagtgac atctgttcca
     3661 ttaacttcaa tacttcctga tgatggatct aaaaaaccta ccaatgctct caaagtagtt
     3721 gatttaccac atcctgaagg cccaagaaat gtaaagaatt ccccttcatg tatatctaaa
     3781 ttcagattat caattgcaac aaaatcacca tatttaattt gaatattatc aaatttaatc
     3841 atctcactaa ctccctctat tactaaacca aaagcctctc tttatttctt ccttaaattt
     3901 agaaataata gagagacttg gacataaaaa ataactctta tttcttattt tacgtattct
     3961 aattcagctt tttctaccca ttcatccaaa tgctttccaa cagcttccca gtcaatattt
     4021 tgtggtttca cttgatcaac aaattttttc gtatcttcag gtaactcttt tagggcatct
     4081 ttatttgcag gaatagatcc aaatttttta ctatattcta cttgaatttc tgattgacca
     4141 aaccaatcaa taaattcttt agctaacgct tgttttttac tagtgcttaa aaccatagtt
     4201 tgttcagtta caaatggtac accaatctca ggagtcataa ctttgaattc aacattttgt
     4261 tctttttgtc cgattaacgc tccagaaccc cagatcatac cgtattgaat tgggctttct
     4321 ttatctaacg ctttaacaac tgagctttca cctttttgaa gagtataggc atttgcaaag
     4381 tattcttttg caacttccca tcctttttct gatacgccta aatctccttt ttcatcaagg
     4441 taacgaacta agatacttgc tagaattgcc cgtcctgtac caccttgaag accataaatt
     4501 gaatatttac ctttatactt actacctaat tcagtccaat ctttaggcat ttcttttaca
     4561 tcaggcgccc caattaaaac taatggttga acaatcacag gattataata attatcttta
     4621 tctgataaag attgatcaat tttatctaac catttaggct tgtactgtac tagtaatttt
     4681 tgatctctaa ttttatttga gtcaacagca ccaattccaa ataccatatc tgcaactgca
     4741 ttattcttct cagcaataac acggtctgct aattgagcgc cagcaatatc aaccattttt
     4801 atattaaaac cagcttcttt tgctttagca gttaaccaat caccacgacc atttgagact
     4861 gagttcgaat agattactaa ttcttgactt ttatcagctt tttcttcaga tgaagaagca
     4921 gtcgtagaat ttgaacctcc agagcaagca gcaagtgtag taagagcaac tcccgttgca
     4981 agtacagtag accaaacttt catttttttc atgataagtt ctcctttttt attattttat
     5041 ttaaattttt cgtgatatgg aacaaattgt ctcatatctt caaatacagt atagtcaata
     5101 cggtttacag taatagttgg aatcttctct aataaaattt cagttaattc tgctctgact
     5161 ttagtaaact cttcttcctc ctcttcggtt agaggaatcc gaagataccc aattgaaata
     5221 tggaattgat atctatcatg attagggaaa caaacacctg ctttttctga gacataagta
     5281 cgaatttctt ctaatctctt tgcagaagct tcatctgcag gttcaactag tatgttttgt
     5341 tttcccattt cagttatacg catatgaatt tcttcatcca acaatggaaa aatttcaagt
     5401 tgtttagcaa agtaatcatg tatttcctgt aaaggtgtat ctagaggaag attactgctc
     5461 caaaactccg tttcacgatt ttcatggcac aacaattcaa ttacagtcat gtgaatagaa
     5521 ttccttggag ttaaagtaaa cttatcgata aatggtaatt ctctataacg tgattgaata
     5581 atatcaacaa cttccatcaa atcttgttta gtataaagat ttgctacaac tgtattccca
     5641 gggaaatgat taaattcccc attctctttg aacttaattt ttgttaagtt tttcatataa
     5701 agaccttctt ttttatattt gacatcggtg tcactatgtt tacattatac aatgaaaccg
     5761 tttcctttgt caagcgctgt caaacatttt ttttaattta tctttcatta aatatgcatt
     5821 tcattaaaag gttaagtaat ttttccaaaa tacagcactc atatagacag tatcatcaat
     5881 tatagccatt gggatttttt gattgctaat tccatgtatc tctacacatg tcttcaatcg
     5941 attttgttgt cctccaattt aattccttat atgctttgtc tgcatttgca taacaagttg
     6001 caacgtctcc tgaacgtctt ggaactattt tataaggaat agggatctta ttaacacttt
     6061 caaatgtatt tacaagttgt aatacactag tgccttctcc cgagcctagg ttatagatat
     6121 aaacatctgt tttttcagat actttttcta aagcttttat atgtcctatt gctaaatcta
     6181 ctacatggat ataatcgcgc acaccagtac cgtcaagcgt atcataatca tttccgaaca
     6241 cacttagttc tgacagctta cctaccgcta cttgtgcaat atagggcatc aagttgttag
     6301 gaattcctga gggatcttcc ccaatcaaac cagactcatg agcaccaatt ggattgaaat
     6361 aacgaagcaa cgcaatactc cattctgaat ctgccacatg aacatctttt aaaatttgct
     6421 caagcatcac tttcgtatac ccataaggat ttgtcgcact tgtttgcata gtctcaatta
     6481 gaggtgactg attgttaatt ccatatacag tcgcacttga agaaaagaca atctttttaa
     6541 cattaaattc tgacatcact tcaacaagtg ccaatgtact cataatatta tttttgtagt
     6601 acatcacagg cttttgcacg gattctccga cagctttata acctgcaaaa tgaattgcag
     6661 catcaatcga ttcttgttca aatacctttc tcaatgctgg tttatcacaa acatctaatt
     6721 cgtaaaacac gggacgtatt cctgtaattg cttcaatacg gtctagcacc aagatgctag
     6781 agttcgaaag gttgtcgaca atgatgactt cctttcctaa atttagtaat tctactacgg
     6841 tatggctacc aatataacca gctccgcctg ttaccaatat tgccattttt gtttcctcct
     6901 aattaattcc aaccgactta acaaatctca taaacgcttc atgcccagac ggtgtattct
     6961 tataaactcc tgcatcttcc agaactctcg caaacacttg tcctgcttcg tgttgaacta
     7021 cgctattaac ctcttcttta ttaatgcgag gatatttttc tttcaattgg tcggcccatt
     7081 ctaaatgata atccgcaatt gcgttatcct ctcctaaaag atattttcca acttcttcta
     7141 actctggttt caaacgaggt ggtaatatcg caagtcccat cacttcgatt aacccgatat
     7201 tttccttttt aatatgttgt acatcttgat gaggatggaa aacaccatct gggtactgtt
     7261 cagtagtatg attatctctt agaacaatat ctaattcata tctcccgtcc actttacgag
     7321 caataggagt caccgtatgg tgtgggacat cttcagtcat agcaatgatg tctacttcta
     7381 aatctgaata ttctctccac ttatttagaa ttttagtagc taaatctaac aagcgatttt
     7441 tattttcact ttgtaaccta attactgaca ttggccattt tacaatacca gcattaacat
     7501 cctcaaagtc tttaaaacga aattcactct caaattttgc tttttccatt gggaaaatat
     7561 gtttccctcc ctggtagtgg ttatgactaa gaatggagcc tcctgagata ggaagatcag
     7621 aatttgaacc agcaaaatat cctggcaaaa tatcaacaat ctccaataat tgttcaaatg
     7681 ttttagaggt aatagccatt ggtacatgtt gactatttaa aaatatcgca tgctcattaa
     7741 agtataagta gggagaatat tggaatcccc atacttcgtc accaagtttc aatcgaataa
     7801 ttctatgatt cgaacgtgct ggataattta ttcgcccctg atatccttca ttttccatac
     7861 atagtaaaca tttgggataa ttagtggctt ttactaattt ttcagcagca attgtttttg
     7921 gatctttttc gggttttgac aaatttatcg taatctctag ctctccgtat ttagttgatg
     7981 ctcgaaactc aatattctta gcaatagcag aagttttaat ataatcacta tctttactta
     8041 acttataaaa ctcttcaact gcttcttgag gtgatatatc atatgaactc caaaaaatat
     8101 catttaatcg actaggtaaa ggaactatga aattcattaa ctctgctcct aaacattcct
     8161 tttcctcgat taaatcttta attttaccgt tttttaaggc gatttccact aagtaatctt
     8221 ttatttgttt caggtcattt tcatcggaaa tgcgatcagt tccctcctca cctattaacg
     8281 ctagtactct atttttcaca tatattttgt caatttcatt atacattccg tattcaatta
     8341 ctctatcaac aaaattatca ataattgttt tcatatattt ttctttctaa tttatgttcc
     8401 catattttct atacattatc catttataaa ttgattgcgt agtatgagca attttatcaa
     8461 ggtgatgaat aatatctaaa gcaccaatta cttcagaaac attcccatca tcttcaaata
     8521 tgtaattcat tattttcttt tcaatatttg tactaagctc ttctatctca ttctgttttt
     8581 gtataacaac catatctaaa catccagatt gttcctctct ataacaagat atagccctat
     8641 tcatatgcag tccgataact tcatgaagta tttttatttc tgaaataatt ttcttcaaaa
     8701 tttcattatt ttgaataatc tgtagatttt ttaaaatttc aacaattcta tccccaatac
     8761 gttcaatgtc agttgatatt tttattacac taataattct tcttaagtca tatgaaacgg
     8821 gatgttgtaa acaaattaac tcatatcctt ttttatcaac atttagaact gactcattta
     8881 tgattaaatc ttctttaatc aattctattc gttcttcatt tgataaatat tcaaataact
     8941 tctcatattt atcaagcaca gatacccaaa tggtctctaa attatttgat aattctataa
     9001 tttcattttc taaatataac cttaacattt aggtacctct tcttaacaaa gttcaatagt
     9061 aacaattaat attttaaaca atatatcaaa catcaataac tacaatactt gcatcatctt
     9121 tctttccata gattggatca atagcagaag aattaaatct catcttaatt aactcttcaa
     9181 aagttttatt ttgattattt tgatagaatt cataaaagcc atcgctcatt aaaacaattt
     9241 gttcactagt aacatctatt tgattaataa tagcatggtc taaaaatctc tcatccaacg
     9301 aacctatcca gtacccactc ggttgattag ataattttct gattttttgt aaaataattt
     9361 ttttatttaa aacactattt gtaccaattg gatcttttat ctcatttttc cctttttcaa
     9421 ataagttatc tactctatga tccgttattt ccatttcgtt tactaacatg acgcagtcac
     9481 ctagcatcat atactccaac tttttttctg aaagtttagc aaatataaaa gcaaatgttg
     9541 gtaagcgata atatagtata ttgaaactag aatagtacac ctctacttct aaaacattgt
     9601 tagaaatcga tttgactgtc ctgattgatt tgtcctatta ttatttcatt ttattatact
     9661 ctgttaattc atatgagttt aaaccgattt catctttaac ctcgagtaaa gcagtttcaa
     9721 atatttgttt aagagttttt gattctttac aattaaccga caaactttct gataaaatat
     9781 gtacaacttc tgagactgaa taacctatct cctctttaga attatataaa tctgtagctc
     9841 caccaataat ccaaaaatac tgattttgtg aacctacaat atcctcattt tctacggaac
     9901 ttccttgtat cgaacaaatt ttatttatct ttaccataat acttcaaccc ttttagtgtc
     9961 aaaagtaaac caattcctgt cactgttaag aatagttcca taatcttgtt cgaaccagtc
    10021 tttggtaatt tttgttttac atctactatt tctttagatt tattaatatg attttcagtt
    10081 tctctgccat ctccaactat tttatagttt acttcttctg tcttattatc ttgtttattg
    10141 tcgatcttgt cattcatttg tctattatct ttacttgagt taaactctcc gttcttctgg
    10201 ttactatcaa ttacattatt tgaattagat tgtttttcct ctttgttttt ttctttttcg
    10261 tttttatcac ttaaattatt tgttacaatt ttgtaaagcc cattctccgt tacaatattg
    10321 aaattaccat cgctatcacg tataacaggt tctttcccgt ttgcattaga tttgatgaat
    10381 gatatatact taccggataa attataaaat tggttattta aaacggttat tttacccttt
    10441 gaatcctcaa taacaattcc ttctttacca ccgaatatac tattctctga cactactaaa
    10501 ttatcactaa ctcgtaataa ttcaatattt ggttgttctg tttccttaga attattatta
    10561 attacatttt ttgttacagt aatatctgat acttttccta aatattctgc actatctttt
    10621 gcaactcgta tcgcttttgt tttaggatcg gcaatattaa atatattttc ggcgataacc
    10681 acctgtttat ttaaatctaa taggtcttta gtgtttttat agctataagc atttactaaa
    10741 gctgctccgc tttctcgata atgtacactc tctcctttaa ctttcttatc aaagcgattt
    10801 cctttgatta atacatcagt gaatcctgta aaacgtacac ctgcatacat catgttatca
    10861 aaatgattat ttaaaatttt aatattagag gggttctgtg tcgacaatgt ttgatagtgt
    10921 gtgccaattg ctgttactaa ttccccagat ttatcacttt tgccaaaata ggaattttga
    10981 atagtcacat tttcagattt tttcccatca tcattcaagg cataaggaaa accttttcta
    11041 gttaatggtt caatctgaat gctctcctta cttatgattt gcccatcctt catcgttttg
    11101 ggtaaggctt gcccaagaaa acgagaatta tcaactaata catttttcga acctgcaatt
    11161 tgaatagcat gcccttgata actatccttg aatgttacat tttttatagt tacgttattt
    11221 gaattcccaa tagcaaatgc acctgaagaa tttataagtg gtagattttt tgctttagtt
    11281 ccttcttcat tcaaagcacc gttcatatca atcgtaccac cagaataact aatatcttct
    11341 gttgggcccc attctacttg cgcaccatca tccgtaaata aacctgtcat aaaaacaatg
    11401 gaagggtgat tcttaatatt tataccattt agaattgtag ctttctcatt caattctaag
    11461 tgtgtatgac tttttaaaaa aacaatttct tttactaaat aagttccttc aggaaaatat
    11521 acatttcctc cacctagccc ttgagctgca gcatctattg catcttgaat tgcttgtcga
    11581 tcatcatgaa tcccatcacc taccgcacca taatctttta cacttaaagc agtatcttca
    11641 aattcttttt tgataattct gtcacttata acatcttcct tataactctt attttcatta
    11701 gtagatgtta ctgtagattc aactgttctg ttgtctaatt gtgaattgga acgaatagta
    11761 ccattagagc tgatactatt aacacttaac gaattatcta aaccattagt ggttgaatta
    11821 gaggcaatca tttcagcaga acgattctga ttaacagttg gtgaattatc taaatcatta
    11881 gtaattgcat tagaagactc ttttgtagcc atcggtgaag aactagtaac aacttcatcc
    11941 gataaaatac cttggcttcc caaaattgaa attgccaata gtaccgagca agtccccacc
    12001 tttaatttac gaatactgaa tacctcatta ggaacaaaat atttcatcag aacctccaat
    12061 ttttttacta tttttaacaa ttgattatta cttttcttaa aatagataga atgacaccgc
    12121 tgtcattatc tttatcatat attttccaaa ttgaattgtc aaggaataac acaagaaaat
    12181 attaaaattt atactcttcg gaaatttctt caaactaggt cagtgccgcc ttgccctaag
    12241 tctaggttac tgacttggtc agttctatag tagactgaaa ctataatagt acacctctac
    12301 ttctaaaaca ttgttagaaa tcgatttaac tgtcccgatc aatttgtcct attcttgttt
    12361 cattttacta tatctacaac ctcaaagcag ggttttgagc tatctatggc caacttccta
    12421 gtttgctctt tagccttcca ttcaaaagtg atgctatctt tcttagcttg aatataaaat
    12481 atcccattta ctatatttaa atttgttgat atgttgtaaa ttataaatga aagaacaaat
    12541 accttgtcat acaagcattc gccagggata tttacctgaa tatcgctcat atggcggatt
    12601 gaaactaaaa cactacaata tatttcttaa atagaccttc tataaaagct agatttaacc
    12661 tcgataaaaa tagatgcagt gcttctaaaa tactggaata gggcatatag gtaatcgtag
    12721 acaagtgttt tatagattgt ctcgcaggag atctaatgat gtatagcaag catcactaaa
    12781 catatgggat atttgcgtta ttataatatc aacatgctat aaattctatc atgcaaaaga
    12841 atgactagaa catgaaagac aggcacaaaa ctttgaacaa tattctgaaa acaaaaaaaa
    12901 gacgctagtt tccacaatct cactcatgga aactcacgtc tttcaaaaaa tagggtgaat
    12961 tgaaaactag aacaagacac tagattttct aaatgatgtc tagtaaggat tctaaatgct
    13021 ataccaaatt gctcacatct tatttcaaac cacgggactc ccacaagaaa ggaaaatcct
    13081 ataaaaattc tctctctgag gagaaagagg cctcaactac aggtgtaaac tattatcaat
    13141 tgaaaacaac agtttttaca ctcaattaga ctttttaggg acaggatcac tttcgcttga
    13201 ctgtagtttg tcattttttt gataaagtta gcactttttc agaaactgtt ttgaaagtct
    13261 caatgatata gtctacttct tcatcgctta atttagtatg aagagggagg gtaatttcat
    13321 tctcaaagaa ggcataggcc ttaggatagt tcgtcatatc aaatccaaga ttcttatagg
    13381 ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc aattcctgct ttagccaatt
    13441 cttggatgat gaggttgcgt tcttctaggc ttgctccttc tacacgggtg atgtagaggt
    13501 ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg atggatgcga gaacctgcaa
    13561 aaccactatc atagcggtcc acaatgtcct tacggcgttg caacaaactt ggatagcggt
    13621 ccaattgtac caaaccaagt gaagccatga tatcggtcat gttgcactta taggctggtg
    13681 taacgatatc gtattcccat gaccccagtt gcatcttggc aagagcatcc ttagtttgcc
    13741 cgtgaaggga aaggatttgg aattccttgt acatctcttc gtcatcaatc actggattgg
    13801 ctttccaagt cgcacttcca ccttctgccg ttgtaaagtt cttaacagca tggaatgaga
    13861 aggaagtaaa atcagcgata gaaccagaag gttgtccttt ataagtagat cccaaagcgt
    13921 gggcactatc agagacaatg acaatacggt taaaggcctt ttgccacttg cttgaagcgg
    13981 taaagaagtc acgttttttc tccacgactt ggaacaaacg gtcataatcg caaacaatcc
    14041 ctgcgagctc tactgggata atcaccttag ttttctcagt gatagcttgc tcaagcaggt
    14101 catagtccat ctcaaacgta tctgcttgga tatccaccat gacaggggtt gctcccacgt
    14161 gcgtaatgac actacatgaa gccgtatagg tcatggctgg aacgatgact tcatcaccag
    14221 gtcccacttc caaaacgcgt aaaatcaact ccagagcggc tgtcgcagag ttgagacaaa
    14281 cagtcttagg tgtctgtgtg taaagagaca agcggcgctc cagttctttt gttttaggac
    14341 ctgttgtgat ccaaccagaa cgcagggtat ccgctacttc agcaatttct gcttctgtga
    14401 tatcaggcgg tgaaaatgga atattgtaat ttggcattga tttgctcctt ttatctgtac
    14461 tcattttctt atgactactt tattttagta cctcaaacac ggtttgaaac atgattttga
    14521 tgtccccaaa gaaactaaac tctcggagat aggcgaggtt atagcgcatc ttttcaggaa
    14581 gaacatgctc cacataggcc tgatcaactg acagaccttt ctccgtcatt tgactgatga
    14641 tggtgtcctc atccttgtag ttgatgctgg ctggagaggt aattcctgct tgcaagagca
    14701 aggttgccat catttcaggg ctatactgct ctgtataacg tggcacttca ggtcgtgtac
    14761 cgacaaagga catctcacct ttaaggacat tgaccaactg aggcagttcg tccaaacgga
    14821 cacgtcggat gaaatttcca accttggtaa tacggctatc gttagcagaa gtcaccagac
    14881 ttcctttttt atccgcatcc gtcaccatgg tacggaactt ccaaatcttg aaccgacggt
    14941 tgtactgggt cacacgctct tgcttgtaaa tcactggccc cttgctatcc aacttgatcc
    15001 aaatgctcaa gatgagaaag atgggagaag ttagaaccag taagaccaag gccaaaaccc
    15061 agtccaagca acgcttgaaa atcagcgaac ccttcctttt agagacaagc tggtagtaag
    15121 actcaacctc gcttgatttc atttccacag gcaagtcttc ccatttcagc atgctgttct
    15181 cctttgtttt tattatacta tttgtcaaca tttttcatta taccacaaaa tggaaaaggc
    15241 ggtgaaagaa atctgtaatt tgaaggattt ccttctagta ctcaatgaaa atcaaagtac
    15301 agctttgaga ttgcagataa agctgacatg gtttaaagag attttcaaag agtataggcc
    15361 atggcccctg cctgcaaact atacatcttg tgataggttc ctcccagagt caagagttcc
    15421 tcatgggttc cactctcgat aatgcgtccc ttatccaaga catagatgca gttggcgtct
    15481 tgaatagtag aaaggcggtg agcgatagca atagttgttc ggccctgtct catcttcgcc
    15541 agagaagctt gaaccaaact ttctgtttca gagtcaatat tggctgtcgc ttcatccaaa
    15601 atcaggattt taggctggct ggcgactgtt ctagcaaagg caagaagctg gcgctgccca
    15661 gtagagaagc tcgaaccacg ctcggaaaca ggagagtcgt acccctgagg aagttcttga
    15721 ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa cctgctcatc actgatttct
    15781 tggtacatgg cgatattgga cttaatagtt ccatgataga ggaagggttc ctgtaaaacc
    15841 aaaccgatgt tttttctcag ctcttcttga ctgaaatccc tgatatccac atcatccaag
    15901 agaactctcc ctgactggaa ttcataaaag cgcatgagga cattgataat agacgatttc
    15961 cctgaacctg tatgacctac aaaggcaatg gtttcaccct tattaacaga gaaagaaatg
    16021 tcatccagaa tcggatgttt accgtcatac gagaaacaca catgttcaaa acggatattg
    16081 ccttctttga ctttggcttg cccattttct tgaaggggct cataggtcct ctcatcgatt
    16141 aaggcaaaga cacggcctgc agaaaccata gacgtttgca gtgttgaaaa gttttgcgtc
    16201 acctcaatca aagggtcaaa gaggcggttg atgtactgga taaaagcata catggtcccg
    16261 gccgttatcc cgatagaaag accacgatag ccaaaatagg tcatcaagac agcataacct
    16321 agaagtttca acaaactcat ggcaggtctc aaaaagaggg catccaaggc tacagaacgg
    16381 ttggcatagg ccaagtgctc ttggttgatt tcatcaaatt ctgcctgcag gcgcttctct
    16441 tgattaaaag cctgaataat cctgattccc tcgatattct ctgccagctt actattgata
    16501 tctgacaaga gacttctggt tttctcgatg attttcactg acttttttcg atagagattg
    16561 accaaaagga aaatcaaggg gagaaagagc aagactaatg ctgtcaaacg aaaatccagc
    16621 accaacatgg tataaagggt tgtcagaaag ataaaaactg ctgagataaa gctggataaa
    16681 atcccagaaa acatatcact aatcgtctcg gtatcgttgg tcaaacgaga aacgatagaa
    16741 cctgctggcg tcttgtcaaa gtaagacatg cccagtttct ccatattggc aaaggcatcc
    16801 cgacgaatat ccctaacaat actgtaagac acgcgcgcaa agagaagatt gccgacatac
    16861 tgaactacag tttgtaggat gtagagacca tagtagacca gcaaaacggt cacggctagt
    16921 tggttaagat tgctgagata ctggtcgata aagtgggaag ccacaagggg aatgacactt
    16981 ttaatgaccg tcgtcgctag gagaaaactg agtgccaaaa aggtaaggag tccataaggc
    17041 ttgagatagg acatcaagcg cttcaataca gtccattgtt cttgtttatt ctgcatcttc
    17101 ttctcccttc atttccagct gctgagactg gtaggtttgg gcataccagc catccaaagc
    17161 tagcaagtct tcgtgcctgc ctcgttcgat aatttgacca ttttgcagga ctaaaatcaa
    17221 atctgcatgg acaactgcac tcaggcgatg ggcagtgata atggttgtct tgtcctttcg
    17281 cgtctccttg aggttgtcga taatcgcata ctctgtcttg gcatctacgg cggataagga
    17341 atcatccaaa atcaagatat cagggtctaa aatcatagcc cgactcatag ccaaccgttg
    17401 cttttgacca ccagaaagac tgactccttt ttcaccaatc agcgtatcaa atccttgagg
    17461 catgtctaca atatcttggt aaactcgggc tagcttagta gcttcctcga ccgctgaaag
    17521 gggcaagtta ggattgccaa agcggatatt gtctaggatt gaagtcgcaa aaagaaactg
    17581 gtcctgagga acatagccca tgagactgcg aaggtctgtc agacgatagt cccgaatatc
    17641 gtgaccgttt agataaatgg cgcccttatc cacatcgtat tcacgcaaga ggagcttgat
    17701 taaggacgtt ttcccagagc ctgtctgccc aaccaagccc agtgtttgcc cttttgccaa
    17761 actaaagtga atatccgtca gtgtttcctc attttcaaaa gcaaagctgt caatggcata
    17821 ctccaaacgc ccattttcaa taccatccag aggaaactcc gggtcttgta caggagattc
    17881 ctgagacaaa agattttcaa tccgctggta agaaaccttc cctcgctgag tagtattaaa
    17941 gaggaagccg atggccataa gaggccagac cagcatatcc aaatagctga taaaggtgac
    18001 tagattccca actgtaatct gcccttcctg aaccaccaag gagccaacca aaagcgttaa
    18061 aacataggac gaaccaacaa acaagagaac catagggtca aagagactat catatttcat
    18121 ggtttgcagg ttcttttgga aggttaattc attgactgcc tgaaaagact tcaactcgtc
    18181 tgcctgataa ccgaaagact tggtcacttt gatacctgat acggactcct gtaccttgtt
    18241 attgagttca gaaaaagcag cttgggattc gccaaaggcc ttatgagtct ttctccctag
    18301 gcgactagtc gcataggcca tgaaaggtag ggggagaatg gcaacaagag tcatctgcca
    18361 tgagatgcta aagagcatgg tcaacaaagt caccagagcc gtgatagagg catccaccgc
    18421 agacatgaca ccgccacctg ctaaacgagt caaggcattg atatcattgg ttgcgtgtgc
    18481 catcagatca cccgtccgat aggtttgata aaaggctgac gacatttttg tgaaatgctt
    18541 aaacaagcga gaccgcatga tctgtcccaa gcaataagag gtcccaagga tatacatacg
    18601 ccacacatag cgcaaatagt acataccaaa ggctgcaagt agcaagtaaa ataggctaag
    18661 aaggaggtcc tgctgggtta attgccccga tgtgatggca tcaataaccc gccccataac
    18721 cataggagga atgagattga ggacggaaac caagaccagg gccacaattc cgactagata
    18781 acggcgtttt tctaacttga aaaaccacca aagtttttga ataatggaca taaaatccct
    18841 ttctgattgc aaatggaaac ctgaggccaa tactcaatga aaatcaaaga gcaaactagg
    18901 aaactagccg caggctgctc aaagcactgc tttgaggttg tagatagaac tgacgaagtc
    18961 agtaacctac atacggcaag gcgacgttga cgcggtttga agagattttc gaagagtaca
    19021 agaccccagg tttttctttt tcataagtta cgactgtaac agcacccttg tcatattcag
    19081 caataaagat attggctaca ttgtcatgcc cttgtttact gaggttatca agcaaccact
    19141 cttcgctacg accaatcgat tccaagacat ctacttgaat cacaccgtca gtcacaactg
    19201 gatacttagg attttcatct cccatttgca caacgataag ttgcccattt tgctcttgca
    19261 cagctcgttt gacttgcttc atctggaaaa tcccttggct acgaagtttg agggctacat
    19321 ccgatgcaga caaaccaact gaacgacagg cttctgggtc aatattccca tttttgataa
    19381 ggagagttgg cttaccatca atcaaacgtt tcacaaagtg aacattgttg ttgagccatt
    19441 tgagagtcaa gaccagtttg attaaaattt cgatataatt aagtgtcatt tgttcacatc
    19501 caccagttca attgcgtctg tcttatacaa ttcgactttc tctaacaggt acttgtctgg
    19561 ctcacttccg tttagggcac gataatagcg atctcccacc ttgataagtg cgccatctgt
    19621 gtttgtggaa gtattaacat agacttctga cttgtctact cccaaatctt tggaaacaac
    19681 ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa acttgattgt tttgataagt
    19741 cgtgatgctg accaaaagca gagctaaata aggccagagc tgaaatcatg accaactcac
    19801 gaaattcggt tcccttttta tcatggtatg ccttgaaagc aaaaaaaact gtcacagcta
    19861 atagaacaat cccaaagcca accatgatac cattttgctg accgatttgg ctgagtacat
    19921 agtcataaga gtagaatttc atatattttc actctctttc ataaaatcat tcttaattat
    19981 aaacgaaaga gagtaatttt tcaaaccata cgttggggaa atagatcttt ttttggtata
    20041 ataaaatcta taatctgaat gaaaaaggta actttatgaa acttatctca tggaatattg
    20101 attccctaaa cgctgcccta actagtgact cagctcgtgc caaattgtcc caagaagtcc
    20161 tacaaacctt ggtcgctgaa aatgctgata ttattgctat ccaagaaacc aagctttctg
    20221 ccaaaggacc tacaaagaaa cacgtggaaa ttttagaaga actcttccca ggctacgaaa
    20281 acacgtggcg ctcttcccaa gagcctgccc gtaaaggcta tgctggaacc atgttccttt
    20341 ataagaaaga acttacgcct acgatcagct tcccagaaat cggtgcccct tctaccatgg
    20401 acttggaagg ccgtatcatc actctagaat ttgatgcatt tttcgtaacc caagtttaca
    20461 ctccaaacgc tggtgacggt ctcaaacgct tggaagaacg ccaagtctgg gatgttaaat
    20521 atgctgagta tttggctgaa ctagacaaag aaaaaccagt ccttgcgacc ggtgactaca
    20581 acgtagccca caatgaaatc gaccttgcaa atcctgctag caaccgccgt tcacctggat
    20641 ttactgacga ggaacgtgct ggatttacca accttttggc aactggattt acagacacct
    20701 tccgccatgt tcatggcgat gttcctgaac gctacacttg gtgggcacaa cgcagcaaaa
    20761 cttctaaaat caacaataca ggctggagaa tcgactactg gctcacaagt aaccgtatcg
    20821 ctgacaaggt cactaaatct gatatgattg actcaggtgc tcgccaagac catacaccga
    20881 ttgtcttgga aattgacttg taaggatttt ctatatggac tacaatgcgg tcattcccga
    20941 gttgcttgta tcgaatatcg aacagtctcg gtccttctac tgtggtttac tgggttttag
    21001 gattgaatac caacgtccag aagaaaactt tctctttctt tctcttgaag agtgtcaact
    21061 aatgttagag gagggaacaa aggatcaact agctgaactg acctacccct ttggtcgtgg
    21121 agtcaatctc tcctttggca taaaggatgt ttcaaaactc tattaaagag tgatgaaggc
    21181 aaactatcct atttatcgtc ccttgaccaa aagaaagttt cgtgtcagtg atccctatat
    21241 ctatcctcat aaatttgcag ttttggatcc aaatggctat tttttaagat ttagcgagta
    21301 gaataataaa aattgggaaa agtctttaaa gttagaaaaa ggcatattgt caggtgttta
    21361 aaaacttgat agtatgcctt ttatgatgga aaaatcttct aatactcttc gaaaatctct
    21421 tcaagccaca tcaacgtcgc cttaccgtag gtatatgata ctgactctgt caattctatc
    21481 cacaacctca aaacagtgat ttgaggttgt ggatagcttc ctagtttgct ctttgatttt
    21541 catttagtat aaatgttagc ttacaatgca gtttttgttc actccttctt ctgtttgttc
    21601 gttttttaaa ccaaaatact aacaaaatag ttgatttata aagttattta gtgtaaaata
    21661 aaaacattgg ctcaaaccta tttaaaattg aatatcgttt tacttgttta tgtcgtgaat
    21721 tggcacgacg tttctacaag gtgccggaac acctaacaat aagtaagtca gcagtgagat
    21781 atggccgttt ttgccatgcc tatttggggg acttacttag agattaagta ggtctttttt
    21841 gaatattttt aatatttccc ttaattagtg cggacgggag gtgaaattat cctgtgaata
    21901 atttcaggaa tccagggaat ttcatcccta atttttgagc ccctagctct ttcatttcta
    21961 ggcttaggct aaaatagttc cccgaactat tttactctca aaaatcccgt catagacaat
    22021 aacaagatta ttgtctatga taccactaca acgggaaata tttgataaga ctcgcttcgc
    22081 tcgtaatagt tttatcaaat atatagtatt agcaaaaggg atcactatag aaacatttaa
    22141 acaacaagta aattaacttt tagactttag gaggtcttat gaaattatta gaagagcgca
    22201 tcctcaagga tgggcatatc ttgggtgata acatcctcaa ggtagattcc tttttaaccc
    22261 accaagttga ctttagcttg atgcgagaga ttggtaaggt ttttgcggaa aaatttgctg
    22321 ctgctggcat taccaaggtc gtaaccattg aagcgtcggg tattgcccca gccgttttta
    22381 cagctgaagc cttaaacgtt cccatgattt tcgccaaaaa agctaagaac atcaccatga
    22441 acgaaggcat cttaactact caagtctact cctttaccaa gcaggtgacc agcactgttt
    22501 ctatcgctgg aaaattcctc tcaccagagg acaaggtttt gattatcgac gatttccttg
    22561 ctaatggcca agctgctaaa ggcttgattc aaatcatcga acaggccggt gccacagtcc
    22621 aagctatcgg tatcgtgatt gagaaatcct tccaagatgg tcgtgatttg cttgaaaaag
    22681 caggctaccc tgtcctatca cttgctcgct tggatcgttt tgaaaatggt caggtcgtat
    22741 ttaaggaggc agatctctaa tgcaaactca agaaaaacac tcgcaagcag ccgttctggg
    22801 cttgcagcac ttactagcca tgtactcagg atctatcctg gttcccatca tgattgcgac
    22861 agcccttggc tattcagctg agcagttgac ctacctgatt tctacagata tcttcatgtg
    22921 tggggtggca accttcctcc aactccaact caacaaatac tttgggattg gactcccagt
    22981 cgttcttgga gttgcattcc agtcggtcgc tcccttgatt atgattgggc aaagccatgg
    23041 tagtggcgct atgtttggtg cccttatcgc atctgggatt tacgtggttc ttgtttcagg
    23101 catcttctca aaagtagcca atctcttccc atctatcgta acaggatctg ttattaccac
    23161 gattggttta accttgatcc ctgtcgctat tggaaatatg ggaaataacg ttccagagcc
    23221 aactggtcaa agtctcttgc ttgcagctat tactgttctg attatcctct tgatcaacat
    23281 ctttaccaaa ggatttatca agtctatctc tattttgatt ggtctggttg ttggaactgc
    23341 cattgctgct actatgggct tggtggactt ctctcctgtt gcggtagctc cacttgtcca
    23401 tgtcccaact ccactctact ttgggatgcc aacctttgaa atctcatcta ttgccatgat
    23461 gtgtatcatc gcaacggtgt ctatggttga gtcaactggt gtttatctag ccttgtctga
    23521 tatcacaaaa gatccaatcg acagcacgcg ccttcgcaac ggttaccgcg cagaaggttt
    23581 ggcggtactt ctcggaggaa tctttaacac cttcccttac accggatttt cacaaaacgt
    23641 tggtttggtt aaattgtcag gcatcaaaaa acgcctgcca atctactacg cagctggttt
    23701 cctggttctc cttggactgc ttcctaagtt tggtgccctt gcccaaatca ttccaagctc
    23761 cgtcctcggc ggtgccatgc tggtgatgtt tggttttgta tctattcaag ggatgcaaat
    23821 cctcgcccga gttgactttg ctaacaatga acacaacttc cttatcgcag ctgtttcaat
    23881 cgctgcaggt gtcggtctca acaacagtaa tctctttgtc agcatgccga cagccttcca
    23941 aatgttcttc tcaaacggaa tcgtcgtagc cagcctactc gccattgtcc tcaatgccgt
    24001 attaaatcat aaaaagaaat aagaaaaaga ggtgcgagcc tcttttttgt ttatcacaaa
    24061 ttgattataa atacaatcaa tcccaattcc catctaattg aattggacct atttcaaatt
    24121 ctttaaaata ttatgttcca aatcgttaat attatataag aatggtaaaa tatcaaatgt
    24181 ttctcgtaaa ttattcttag ccttatacca accttgtcca tcagtaatcc acataaactc
    24241 aacattagga atagctttag tttcttcagc aatcattttg taagatctag ccgtctcatt
    24301 taattttgaa ccacttcctg aataaaaatt aacctcaatc agataaagca cttgttcatt
    24361 ttttatgaca aaatcaaaac gtttcacagt attcccatca ttcgtaatag cagataaatc
    24421 gacagaaaaa atttcctcta tttcattttg ttcaatctct ttaaataaat tctctcctaa
    24481 aatataccct tcagcttcaa gatagctttg aacaatattt tccatcgcat ctccagtccg
    24541 atttttgcgc ccattagtat ccataccaac ctcaacacct gtaacgtagt caactaaatt
    24601 tgatactaaa tgattttgca ataaatcaaa tatacctgat ttttccaaaa acatagtata
    24661 ttcttcaata ctatagtttc gtttactaaa atcaaaatag aaatctttta tcggatcctt
    24721 aacaataatc gtatctctca aacgtttagc aataagtaga ggcacaactt tcaaaatttc
    24781 tggataattt tgatataagt ctaaaaaatc ctcttgtata tttttactac caataagact
    24841 attcataata tttagagcaa cttttatact agatacattt ttataaacct taggaaaatc
    24901 tgtataataa gtccagtcag ctactgtgtc ggtcatcgtt gacaaccact catcaaaatt
    24961 tctagtttgt ttcattttct gcctccaacc tcttccttgc aatttttaaa tattcttttt
    25021 cagcatcgat acctataaat cttctaccta accgcttcgc aacaacaccc gtagtgccac
    25081 taccaacaaa tgggtctaga atatagtcac cctctttagt agaggctaaa ataatacgtt
    25141 ctaacaaata ctctggtttt tgagttggat gtttcccagc ccatttttca actttctttg
    25201 ttaaagaacc ggtccagaca tctttcattt gttttccatc attcaattct ttcattaaat
    25261 cataattgta gtaatgacga gcttttttat cattttttct ggcccataaa atggtttcag
    25321 tagaatgggt aaaataacga caagataaat tgggggcagg gtttgttttc tgccaagtaa
    25381 tattattcag aattttaaaa ccttcttgtt ctaatgccat tccaactgag tatatgttgt
    25441 gcaaactacc tgaaatccat accgtcccat taggcttcag aacttctttt gctaggcgaa
    25501 tccatttacg attaaactca tgtttttctt cgaatgaaga aattttatcc caatctcctt
    25561 tatcaacaga aactacttgt cccccagaat tagatattcc accattactt aaaaaataag
    25621 gtggatcagc aaaaatcata tccatacttt ctggtttcat ttttgataag aacttgaacg
    25681 tatctgaatg aacaagaatc atcttatttt tattgtagta tggttttgtc ataagaacac
    25741 ctccatactt atattcgtta tttttcataa tttgtgacta taatttcaga aatttttcct
    25801 cgacttgaag attttgctcc attagttcgg gtagcttcaa cataatgtat attaaaatcc
    25861 ttatacaact cctctactaa agcactagaa gaatttgata acataacata agctcctgta
    25921 tcactcaatc tcttaaaggc atctcttaat cttacttgat ctgcaaaaga gaatccctca
    25981 tgagtataag acgtaaatgc actcgtctca gacaatggaa tatatggagg gtcaaaatac
    26041 acaaaatctc ctgttcgaac atctacaatt gccttttcaa aatctcccac tttaatttct
    26101 agttgattgt tatttatata aactgaaata gcagatatca attcctcatc aacaatttta
    26161 ggattcttat aacgtccata tggaacatta aattgattct tagaattcac acgatataga
    26221 ccattaaagt tcactctcaa catatataga atacgtgcag ctctttgtac ttcggacatc
    26281 atatctattc tttcatcacg atctgcagaa cgtaaatcta aataatattc ttttgaatta
    26341 tattcctgat gaactttcaa aatttcaatc aattcttgag gattgtcctt aatttgttga
    26401 tagcaattta ttagttcagc gttaaaatca ttaataactg catctttagg agccaaatca
    26461 aaaaataaag ctccacctcc aacaaaaggt tcgaaatacc tgttataggt tttaggtatt
    26521 aattctctaa taacaggcaa taattgtctt ttaccacctg tccatttcgt gaacggttgt
    26581 aaagtaactt tctttatttc ttttatcttc atgcttttaa ttataccata gaaattaaaa
    26641 cacaactctt gtattttcta ccacattact aaattttcta ttttagaatt aaatcatatc
    26701 aatatcaaaa aatgagtaag gcaaatctta taaattccaa aattcacctc actctattaa
    26761 attactcttt atatccttac ctgtctgtct tctgaccgct ggcctgtgac aaacatggta
    26821 aaggttgctt tgcagacatt tctgccttct tgattggtga tatccacatc cattacacag
    26881 gttgtacgac cttgatggac acattctcct ttaatggtca atacatcgtc gagttttcct
    26941 gccttaaggt agttgataga ggattggagt gtcaccccat caagtcccag cgagataacc
    27001 accaaaccac tgatttggtc acatagcgtg aatagatagc caccatgggc attgccatag
    27061 tagttgagcg acgagttcac tactttggtc gtcaccacaa cgtgaccatc tctcattttt
    27121 tcaatttcgt aattttcaaa ggcagatata gcgtcaaaat gaaagtcttt catcgtttcc
    27181 tcctgatatt tcaaacgaca ctatgatact actttttata ggactgtgca aggagaaagc
    27241 tcctagtcta gtaaaattcc gacctgttcc acaaagcgca taaaggctgt ctgaccttgt
    27301 tctgtctgct tgtagactcc tgcatcctca agtacacgca caaagatagc acccacagag
    27361 tccttgacga ttgcaagggc tttttcttta tccgttaggt ctggatgttg ggatttgagt
    27421 tggtctgccc actcctgatg ataatcggca actgtaacag cttctcctac aagatagcta
    27481 gcgacttgct ccacttcttc tttcagacgt ggtggcaaga ttgccaagcc catgacctca
    27541 atcaagccga tattttcctt cttgatatgt tggacatcct tgtggggatg atagatgcca
    27601 tcaggatgct ctgctgaagt ctgattgtct cgcaagacca agtccaactc aaactgtcca
    27661 tcacgcttac gcgctattgg tgtgatggtg tgatgcggtg tcccgtctgt ctctgctaaa
    27721 atctgcacac tagaatctga atactgacgc cattcctgga aaatcttatc agctaagtta
    27781 atcaaatcct ctttggaatc cgaagtcaag cgtaggacag acattggcca cttgataatt
    27841 ccagccttga cctgctcaaa accagcaaat cggaaggtct tttgcaaggg agccaattcc
    27901 ataggaaata cgtgacggcc tccctgataa tgatcatgag ttagaataga gccccccaca
    27961 atcggcaggt cggcattaga tccagcaaaa tatcctggaa actgctctac gatagccaac
    28021 agacgttcaa aactctgacg actaatggcc atgggacgat gctggccatc taaaaagata
    28081 caatgctcat taaagtaagc atagggcgaa tactggaacc cccattcctg accaaccatt
    28141 tcaaaacgga taatccggtg gttgctgcga gctgggtggt tgacccgacc atggtaaccc
    28201 tcattctcta aacaaagttg acactgagga taattactag cttgcaccaa cttggctacc
    28261 gcaatctctt tcggatcctt ttcaggctta gagagattga tggtaatttc aagttctcca
    28321 taatcagatg gaacacgata agcgatattt ttagcaatgg ccttgagttt gatgtagtca
    28381 tttttccgac tgagttgata aaaatcctct atcgcttgct caggagagta ggcataggct
    28441 tcccagaagt cacgattgac ctgactcgga caaggagtca ccaagtccat cagttcagta
    28501 ccaaggattt cacgcgcagt ctgactatcc tcaatcatct ctaatcgaac ggcttcctca
    28561 actagctggt ccttgaggtc aatcaattta tccagattgg tctcaacttc caaaacacct
    28621 tctcccactc gtgccaaaac acgattggtc aggtagattc gatccatttc ctcaaatgaa
    28681 ctttcagaaa tgacatgtgt tacaaattta tctactaagg tcactataga gcctcctttt
    28741 gactagtcaa ggacgcgagt cccacctgca acttcagcga tatagaagct tggagcgtat
    28801 ccaactactt cctcgtagtg tttgcctaca gcttccttaa aggcctcaac agtatctttt
    28861 tgaaccaagg caatggcaca gccaccaaaa ccagcccctg tcatacgagc accgagaact
    28921 ccttcttgtg cccaagctgt gtgaacaaga gtatccaatt ccaaaccagt tacttcataa
    28981 tcatgctcca gagaaacgtg tgacgcattc atcaaacgac caaatgtttc caaatcacct
    29041 gcttgaaggg ctgcttgagc tttaagggta cgttggtttt caagcacagc atggcgagca
    29101 cgtttcaaac gattttcatc tttaatcaaa tagctatatt ggtcaacggc ccactcgtcc
    29161 aattcaccca gggtctgaat atccaaggca acttgcaatt cttccactgc tttttcacac
    29221 tcagcacgac gttcattgta tttagagtcc gccaattcac ggcgtttgtt ggtgttcatg
    29281 ataacaacga cattgtcctt caaatcaagt ggcaccaaat catactctaa ggtgttggta
    29341 tcaaggtaaa tagcacgttg atcagccccc ataccaatag caaactggtc catgatacca
    29401 gagttgactc cgataaagtt attttctgtt tgttttccga ttttaaccaa atcgagacgc
    29461 tctaatttta aatcaaagag atgctctgcc actacccctg tcaagagctc caaggatgct
    29521 gaagaagaca aaccagcacc atttgggata ttcccataaa cataaaaatc aaaacctttg
    29581 tcaatcacgt gcccagcttc ttgcaagaaa tgaaggacac cttttggata attggtccag
    29641 ttgtgctctt tttcaaactt gaggtcagcg agaggcactt cgataatgcc cttgtcctca
    29701 aagttagctg agtagaaacg caagacttgg tcatcacgct tacgagctgc accgtaagtt
    29761 cccaaggaaa tagcagcagg aaaaacgtgc ccaccgttgt agtctgtgtg ttcaccaatc
    29821 aaattaatac ggcctggtga aaagaaggtt tggtctgctt cttgaccaaa aacagcaaga
    29881 aagtctttgc gaaggacttc agtagtaaga tgttgtgcca tatgaattct cctttgactg
    29941 tccgttaagc catcttaacg tgtaatcgtt ttctttctat tgtatccaag gaatttccca
    30001 aggtcaatcc tttttactaa aattttacta aaatatcagt aaaaagaaga aaaatatgat
    30061 atactaacct aatcaaggag gatttatggc taccttaaaa gacattgcac agctagcctc
    30121 tgtctcaatc gcgaccgtat cccgtgtcct caaccgcgac cagagcctat ctgttacaga
    30181 agaaaccaga caccgtattt taaccgttgc tgaagagcta ggctacacca aacatctcaa
    30241 gacaggcgag tcccacaagc ccaagcaaaa gattgccatt atccaatggg tcagcgaaca
    30301 aggggagcta gacgacctct actactacca gattcgccta ggaatagaaa aaagagccca
    30361 agagttggac tacgatatct tgcgctattt taatgaccat ccttttacct taagcgagga
    30421 agtgattggg attctctgca tcggaaaatt tagccgagct cagatttctg cctttgaaga
    30481 ataccaaaag cctcttgtat ttctagacag cgatacactt tccctgggac atacctgtat
    30541 tatcacggat ttttacactg ctatgaaaca ggttgtcgat tatttcctca gtcaagggat
    30601 ggaccgcatc gggattctaa cagggcttga ggaaacaaca gaccaagaag aaatcattca
    30661 ggacaagcgt ctagaaaact tcaaaaacta cagtcaagcg aggggaatct atcatgatga
    30721 actggtcttt caaggaagat ttactgccca gtctggctat gacttaatga aggaggccat
    30781 tcagagcttg ggagaccaac ttccgccagc atttttcgca gccagcgata gtttagctat
    30841 cggtgccctc cgtgccctcc aagaagctgg aatcagcctg ccagatcgcg tcagcctcat
    30901 ttcattcaac gacaccagtc tgaccaaaca ggtctatcct cccctctcta gtattacagt
    30961 ttatactgaa gaaatggggc gagcaggtat ggatattctt aacaaggaag tcctccacgg
    31021 tcgcaaaatt cctagcctga ccatgctggg aaccagactg acattaagag aaagtaccct
    31081 aaatcaagaa taggataaca taaaaaacga atagagttct aaaactccta ttcgtttttt
    31141 attcgattac aatcatagac ttaattgtct tacgttcatc catatctttg taggcttggt
    31201 cgatatcttc cagtttataa cttgaagtaa agacgcgacc tggattgata tcaccatcaa
    31261 ggacggcttt tagtaaaaat tgcttatcgt atgttgtagc agaagctgcc ccacctgcta
    31321 cagagatatt ttgcataaat gtcgaaccaa gagcacgatt attatagtgt gggactccta
    31381 caaagcccat acgccctcca ttatgaagaa cacctagcgc ctgttctata gcagcctccg
    31441 taccaacaca ttcaagtgct gcgtctgctc ctccaccgag gatttcacgc accttggtaa
    31501 ttccttcttg accacgttct gcaacaacag ctgtcgcacc tgactccata gccatctttt
    31561 gacggtcttc atgacggctc ataaggataa tttgtgatgc tccacgcatc ttagccgcga
    31621 tgacagcaca ttgaccaaca gccccatcac cgataacaac aaccttgtcc cctttttgaa
    31681 catttgcaac acgcgccgca tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg
    31741 actggagcat cccttctgta tagtcagaag gttgaccagg gattttaacc agcgcccagt
    31801 ttgcatagtg gaagcgaata tattctgcct gaaaatcacc ccccaaatta ttgccaatat
    31861 gattgtcgca agaaccgtca aatccagcaa gacaggcatc acactcacca catccatgtg
    31921 taaaagggac aatcacaaaa tcacctggtt tcaccgtcgt aatggcttcc acagcttctt
    31981 caacaatccc aatcgcttcg tgtccactat ttttgtgtcc agctttcgtt tctggattac
    32041 ggtacctcca taaatctgaa ccacaaacgc acgcacgaac cacacgaata atcacatcat
    32101 ccgcttctat tatttgcgga cgttcaatgc tagcaagtcc aacctgacct gcctttgtat
    32161 atactgctga tttcatttaa aattttcctt ccttataaag tttaattttg agatttaaac
    32221 gatttaaagc tgtctgtagc tgagacaagc gctcctctaa tttttgcttt tcctcttcta
    32281 aaataccaag cctctcctct ctcgtttcat ctcccttttg gtagagcgac atatagtcaa
    32341 ctaaactatc tacagagaca cccgccgaac gaaaacactt aataaattcc agcgcttcga
    32401 tatcctgatc ttgaaaatca cgaatcccag tagcagtacg agtaatcggt ggcacaagac
    32461 caacccgttc ataataccga atcgtatccg ctgaaattcc caacaaatca ctggcagatt
    32521 taatattcac acgctaacct cctctcattt cattcactga attcacgcta ttctaactca
    32581 cttatcttat tatataactt tgagttgact ccaagtcaag cattttgtat ctaatcgaaa
    32641 aatttttatc attaacaatc atatatctgg agtttataca atgctcttct cttaccaatt
    32701 tttgaaatat ttaaataata aagaaattac tctattccaa ataagatagt acccaagtat
    32761 ttttcacttt tttctaatgt tgatgctcat aactccgttc caagtcacac acctttcgct
    32821 tatgggtttg gtgagtttct aggtcagcat caatttcaat ggtaatattt tgaaaaccac
    32881 aatcttttag gaaaattcga atagactctt tacaagtttc catatgttcc atttctttta
    32941 gacaaacatg gacaatggca tttttttcca aagcatccat agtccagaga ttaagctgat
    33001 taaggctggc cacattgtcc aatcgctcca ggccactctt tacttgcttg atatcaagac
    33061 cttctggcac agcatccaag aaaatcttga gtgtagacca aaaacgtgga agggcttttg
    33121 aaagaataaa gaaagaaatg acaagggaca aaagaggatc taggatatac cagtccgtaa
    33181 atcgaagaac aatcgccatc aggataacag ctacccaccc tagcgtatct tccagaaaat
    33241 gcagactcag aatagactca ttctttgtct ttcccttacc aaccaccaga ctcgctaaca
    33301 gattgatagt aatcgcaata attcctaacc agagaatccc ctcatcattg actggttgcg
    33361 gatgcaaaat cttcgtgaca ttttccaaaa tgactagaac agagcccgtt acgagaatca
    33421 cagctgttac caaggctcct agcaggctaa accgcttata gcccaaggtg tactgattgt
    33481 cttcttcacg attggagatt gtttctagaa aagctgatat tccaattgca atcgcatctc
    33541 ccaagtcatg cacagagtca gcaagaacag cgctagaacc aaatactcca cctgcaataa
    33601 actcaacaat ggcataagtc aaatttaaga aaaaagccac ccaaacagca tattttgcct
    33661 tcatatttct cattcctttg ttataataga tttatgaaca ccttgttcat tatcattatc
    33721 cactaaaact caaagaaagg atagaagcaa aacgtcagct ttattcagtt ctgaacaatt
    33781 tgccttaagt gtccatatga ctaacattga ccgccgtatc agcaaaacca aaaaagccat
    33841 ctatcaagct tttatacaac ttttgaatgc taagggctac gaggccacta ctgttcagga
    33901 tatcattgat ctcgcagatg tgggacgatc caccttttac tgtcactatg agagtaagga
    33961 gcttcttctg gaccagctct gccgctacct cttccatcat ctttttgaaa gagagcaagc
    34021 catttcaacc gaggactacc tcgcccacct ctttctccat tttcataaaa accaagacca
    34081 tatcaccagt ctgctatttt ccaaaaatga ctacttcctc cgtcaactcc ataaagagct
    34141 agaacaccat gtctattccg tgctagctga taatttaaaa gaagcccacc ctaatctgcc
    34201 tacttcttac ctccaacact tggtcatgtc caactttatc gagacattga cctggtggct
    34261 caaaaaaggt caagatttca cagaccagga agttgtccaa ttttatctag accttctcat
    34321 tcctaaaaat tgaatataga gtaaagcttc agttgtctta tttctaggtt actgagtttt
    34381 ttatcttttc aacaacaaaa gaggacccgc cgatcctctt tttcatacta taaatccttg
    34441 attatcaact atatctgttt taatcgaaat ctcaaaacag cactttcaaa catcttttcc
    34501 tagttaagta aatcagtatt ctgcttagct gccttgctcc attgatacca accaactaga
    34561 ctgttaatga gataaattag atatttccct tgaatttgca ggctttctcc ccaccagaga
    34621 tagattgaaa agacattggt agccgcccag aatatccact gttcacggta aacagctgtc
    34681 atgaggattt gccctacccc attggttgca tctgtgattg aatcacgata gggacgattg
    34741 gcaccaatag actgataaat gaagccaaag gccaaccacc aaagcacact aatggaaaga
    34801 tactttgtcc agcccttgcc gtccagttta cgcgcgacaa actcctgctt ttccttctta
    34861 aactgtgcct gataaatcca aactagaagt ccaattggct gcatgactgt gaagtaaagt
    34921 gtcgtcagca cctcaccata aaagcctttc tgtagggcca aaataaggta aataacagag
    34981 ttaatcaagc caaaaagata attacttgct cgaccttccg atacaaagat tacacagata
    35041 atccctgtca agctacaaat catcccaatc cagtcaacaa tacgatgttc gtaaaccaac
    35101 tccagccaga gaggaaaact tcctaaaacc agcaaataaa tccactgggc aaaactacga
    35161 tgggcaaaga ggtcatccca gatagccttc atagttcctg aaaatcctaa atcagccata
    35221 gccgcaacca tacgacggta accacctgac atttcaccta gggttgtttt gatattttca
    35281 attttctttt gcaaataagt atgcatcatt tctccttttg tttttaaaga gccgtgtctg
    35341 gatagacttt cggacgcaac gctctattag ataatgaact gcctatacac aagatttcta
    35401 accttagtcg acatgagctg aaacctctta tttgttaagt agttcacaaa atattataca
    35461 cctattttat gaatagtcaa ctgtctttac agtaaaattt tagaaaatca tgaaaatttt
    35521 ctctttcttt ccattttaag tgacattcag tcattctcac atcaaaaaag cccagacgaa
    35581 attgtctgag cattctttta tctagtcgtt taaggaagtt gagttcagta tgtttaaagt
    35641 ctctgtccca tcatttcttc aacaaacctt gttcttggag aaactccttg gctacttgct
    35701 ttgctgactt gccttcaaca ccgacttggt agttgagctg gctcatctgg ctttctgtaa
    35761 tcttaccagc caatgtatta agaactcttt ccaactctgg gtgtttcttg agaagagctt
    35821 ctttcatgag tggagcccct tgataaggtg ggaagagttg cttgtcatct tccaagacct
    35881 gtaaatcata acgctccaat tccgcatcag tcgaataggc atccgtgatt tgaatatccc
    35941 ctgactgaat agcctgatag cgaagggctg gctccatggt cgctacattg agattgagac
    36001 catacattga ttgcaagccc ttatttccat cttcacggtc gttaaactcg agtgtaaaac
    36061 ctgccttcaa ctgcccttcc acttttttca agtctgaaat ggtcttcaag ccatattctt
    36121 gagcaatctt tttcggaaca gctacagcat aggtgttttg ataagacatg ggtttgagat
    36181 aggctagatg atcctgctta gcaatgccat cacgcgccac ctgataaacc tgttctggtt
    36241 catgactcac cttgggtgat ggttgaagca aactttcagt caccgtacca gtaaattcag
    36301 gatagatgtc aatatcgcct tttttcagag cttcataaag gaagcttgtc ttcccaaaat
    36361 tcggtttaac agtcgcagtc atgctggtat tttcttcaat cagcaactta tacatattgg
    36421 ccaaaatttc tggttctgga cctattttcc cagcaataac caagttttcc ttctcttttt
    36481 gaaccaaaag agctggacta taagacagac ccagtaataa agccaccaag gcaaaacctg
    36541 agaaaatcgt ccgtaatttt gctttttcca tcacttttag taggaagtta aaggcaatgg
    36601 ctagcactgc agaagaaagt gccccaatca aaatcaaact ggcattatta cggtcaattc
    36661 ccaaaagaat aaaggaacct agtccccctg caccaatcaa ggccgccaag gttgccgtac
    36721 cgataatcaa aacagctgcc gtccgaatcc cagacatgat aacaggcatg gcgagtggaa
    36781 tttcaaattt cttgagacgt tcccatctgg tcatcccaaa ggcaatccca gcctcttgca
    36841 ggttcggatc aattcccttc agcccagtga tagtattttg caaaataggg aaaatcgcat
    36901 aaatcactag agctgtcaaa gccggcaagg tcccaattcc catcaaaggg ataaagagcc
    36961 ccaacaaggc cagagacggg atggtctgga aaatacctgc aatctgcaag acccagtcgg
    37021 ccagcttctc atgatagcga agaaaaacag ccaagggaat cgcaagcaaa atagctagta
    37081 acaaggtcaa aagcgacaac tgcaaatgtt gagatagagc tgtcaaccaa tcactaaaac
    37141 gatcctgaaa agttgcaatt aaattagtca tgaacactac ctccaaacaa gtctgctaca
    37201 aagtctgttg caggcgcttt taaaattgtc tcgggattcg ctacctggcg aatttctcca
    37261 tcctgcaaga cagcaatacg gtccgccaac ttcaaggctt catccgtatc atgggttaca
    37321 aaaatcgttg tcatcccaaa ctctttatgc aattcttttg tcagaacctg caactgtttt
    37381 ctcgaaatag catccaaggc cgaaaagggt tcatccatga ggaaaatctt gggctgacca
    37441 atcatagctc ggacaatacc gacccgttgc tgttctccac cagataattc actaggtaag
    37501 cgatgcccat actcggctac tggtaaacca accttagcca aaagctcttc tgttttcttc
    37561 gtaatttctt ccttgctcca ccccttcatt tcaggaatga gagcaatatt ttccgcaact
    37621 gttagatttg gaaaaagagc aatagcctgt aaaacataac cagtagaaag acgaagttca
    37681 cgctcatcat agtctttgat gcgcttccca tccatataaa tatttccatc agttggttcc
    37741 aaaagacggt taatcatctt gagcatggtc gtcttacctg acccagaagg ccctactaaa
    37801 accataaatt ccccatcctc aatctgtaag ttgacatctc tcaagacatc cttttctgtg
    37861 tagcgcagtg ctacattttt gtattcaatc attctttgtc ctcaatttaa aacttccctc
    37921 gattggtcaa gtcttctacc ttaggcataa cttccttatt atcccaatgc tccacaattt
    37981 tcccgttctc taaacggaag atatcgtact gggcataagc aacgccatca atctgagtct
    38041 gaccatagct aaccacatag tttccttgtc ctaagagttg gaaaacaaag tcaaaagtga
    38101 cactatattc agccacatag tttttataag cagcacttcc ttgtccaata tcatgattat
    38161 gctgaatcaa atcgtctgcc acataatcac tccactgctc tagctcccca ttttggaaaa
    38221 tttctgtcaa gaaacggcga accagctttt tattttctgc tttcttgtcc aaatccttga
    38281 tttcaaaatc tccaaaaatt tgatctagtt ggtcattttc aggtgttcga tagtagtcaa
    38341 cgacatccca atgctcaaca atacgaccat tctcatccgc acggaaagta tccgtcgtca
    38401 cccattgagc ttctccacca ttcagatatt gatgaacatg aacaaagacc agattgccat
    38461 cctcaatggt gcggacaatc ttaatctgac gctctggatg acgctcaaag aaatctgcaa
    38521 agaaggctgc aaatccttct ttcccgtcag gaacacctgt cgaatgttgg atataggtat
    38581 cccctacaga ctgggcttga gcctcagcaa ctcgtccgtc ttgaatggca tggatgtata
    38641 ggttgtgagc atttttcact tgttgtgaca tattctaaac ctcatttccc ttctctttca
    38701 gattcgccaa aattctttct tgaaaacctt caaattggtg aatttcttcc tctgaaaatc
    38761 ctttgtaaaa gatagtatcc aatttctgac tgacacgatg ccccacttct ttctgggact
    38821 tgcctaactc cgttaaaact aaatacttct tacgcttgtc ttttccacac ggactaacaa
    38881 ttacaagctt ttgttcctct agctttttta tcatagtcgt cagcgtatta ttcgcaagcc
    38941 cagtcgcaag cgcgatatct gtcgcagttg cgcagccagt ttcactattc cataaaaccg
    39001 ctaaaatctt gccctgttca cccctataaa gagcctcagg atcttgactc agtaactttt
    39061 gaaaaatccg cccattcaac aaacgaatat gatgggctag caaatgacta tctctcataa
    39121 cacctccaat ttatttcgat atcgaaatga ataaaacaat tgtaacactc atcgttctat
    39181 ctgtcaacta tttcgatttg gaaataattt ttgataatta tccacaccac catactccgg
    39241 ctcaactaac ttttaacgag agtttctaaa ttccttcgtc ctccagtcta caaaagcctt
    39301 ccatccgtac tatcctatat tttatgaggg gacacatttt tcctatcaga gcatttattt
    39361 taaagataga agtaaatcat aattgcttcc atctgttctt ttatagtata ttgaagttga
    39421 actagggcac tgtatcttct aaaacattga taaaaagcga tttgaatttc ccaatcaatt
    39481 tgttcgtatt tatagcattt tgcaactgga ataggacacc atgactgcta aaagatttct
    39541 ataaattcat ttaatttcct caatcaattt gttcatatct tatttcatcc cgttataatt
    39601 tcaccttacc ctatcttttt cgtagcaccc ttcaaacagc ctatccccta ccgtttgacg
    39661 attcctcact tcgctccact tccattacag aagtttcttc actactatgg tctcggctga
    39721 cttctcatga ttccttgtta ctactatttg aacgctcacg agataggtct tataaaaaat
    39781 gctttgatcc acaatggaat caaagcattt taaagagttc ctcatacata agcgcagaag
    39841 tcgcagttcc tctgtacttg gattcttctc ttttgataaa gctagccaag ttgagcaact
    39901 caggtgctgg atgtttggga tttaggagca attcacgatt gaccaggcct gagagacgaa
    39961 ctgcctgcaa ttgctcattt gtagtaggca gttttttagt agtctctagg agagcagcaa
    40021 ctaaatcttc actcaaatca tgtcgagcat gattgtaaag atcttttata aggctttcta
    40081 ggtttggttc taccatccct accacctccc ttatggttta ataatgttta atcaaatcaa
    40141 ccgttgaacg atccaatttc ttcaccaagg cttgtaagaa agcttgcgct tctaggaagt
    40201 catccattgc atagagggtt tggtgagaat ggatataacg agcgcagaca ccgatagttg
    40261 ttgatgggac accaccattt ttcagatgag ctgcacctgc atctgttccg cctttaccac
    40321 agtagtattg gtacttgata ccagcttctt cagccgttgt caaaaggaaa tccttcatcc
    40381 ctggaagaag caagtgacct ggatcataga aacgaatcaa ggttccatct ccaatcttgc
    40441 cttgaccacc gtagacatca cctgctggtg agcaatcaac tgcgaggaag acttctgggt
    40501 caaacttggt tgtagaggta tgagcgccac gcagaccaac ttcttcttgg acgttagaac
    40561 ccagatagag ttcattgccg agtttttgac ctgataaagc ttcagctagc tcgcttacca
    40621 tgaggacacc gtagcggtta tcccaagctt ttgagatgat atttttttca ttggctgtca
    40681 aaattgcaga actatctggt acaatggtat caccaggacg gatgccaaaa ctttctgcct
    40741 cagccttgtc cgcaaaacca ccatcaaaaa cgatatcggc aatggctggc atggttggtc
    40801 ccccctttcc acgagtcaaa tgcggaggaa cagaacctga aatcacagga atttcatgac
    40861 catcacgagt caagagtttg aaacgttggc tgctaactac catggggttc cagccaccga
    40921 tttctacgac acggaaggta ccatctggct tgatttcgct gaccataaaa ccaacttcgt
    40981 ccatatgaga agcgaccaag acgcgcggtg catccacagc ttctgaatgt ttgataccaa
    41041 aaataccacc caagccatct gtcaccactt catccacatg cggtgtcaac ttttcacgaa
    41101 gataagcacg gacaggcgct tcatgacctg agactgcagc aagttctgtt acttctttaa
    41161 tttttgaaaa taatgttgtc atttcagttc cttctttctt tcatccattt taccactttt
    41221 tataggagaa ggatagtggg aaggtggatt tctaagttag tatcttagtc ctgctctatc
    41281 ttaaaaaagg atagtattct cttgcatgta gtgcaaaatc tagtaaacat tccaaaatta
    41341 actcgaatat ttatttccaa acaaaaaaca atacaccatc aaagttgttt agatttttca
    41401 tgaaatttac agaaaatagt tgacttccct ttcttctttc tttaaatata tagttggttg
    41461 agtttggaat agtacgctgt agctgctaaa acatttctag aaattaattt gactttccta
    41521 atagagttat tcatatctta tttcaatcta ctatagtaca aaactagaaa aggaaaaaat
    41581 catgaccaaa acaattcttg ttacaggtga gactggctac attggctccc ataccgttaa
    41641 agctctttta aatgctggct atcaggtgca tgtcctcgat aatctctcta caggaaatcg
    41701 agcggctgtg gatagtcgtg ctagctttaa agaactggat gtttatgatg ctagcgcctt
    41761 aaagtcttac ttagaagaaa atcagattga tgctgccctc cattgtgcag gtgaaactgt
    41821 tgtgagcgaa agtattgaaa atccaagtaa atacttcact gccaacgttg ctggtatgaa
    41881 ccaagttctc aaagtcttat ctgaagttgg cattcaaaaa atcatgttct cttcgactgc
    41941 ttctctctat ggaaataact gtattgacaa gccggtgact gaagataccc tgctcgaccc
    42001 tgtcaaccct tatgcagaga caaaactgat gggcgaacga atgatttact ggatggccaa
    42061 tcgctacgac tggaaatatg ttattttccg ttactttaat gctgctgggg ctgaaatgga
    42121 tgcttcaaac ggtctgcgtg tgaaaaatcc aactcacatc attccaaata tcaacaagac
    42181 cgcattggga caaaatgata gcttaaaaat atttggagat gactacgata cacgtgacgg
    42241 ttcatgtatt cgagattaca tttatgtctt ggaccttgca taggctcatg ttaaaggaat
    42301 gaactaccta tttcaagaag acagttcttc tcaaatcttt aacttagaaa ctaaaaaagg
    42361 ctatactatc aaagaaatct ttaaaactgc tgaagaatta ctaaattaaa aaatcccaca
    42421 cgagattgtt gctcgacgtg ctagtgaccc agccagtgtc ctagcagatg cttcaaaagc
    42481 taaacaatat cttgattgga cggctagcta ctccctcgaa gatattattt tatcagatta
    42541 aggtaaaaac attttagaat aggataacaa aggagaaagt cttgttgctc tctccttgtt
    42601 gtatttatta aattgtcaga aattttattg acagattaga aaaataatgt tacatttata
    42661 tccgcagata tctttcgata ccaaatctac atgaaaggac ggggtatgaa actttctcat
    42721 tatttaattg gcttacttct actcctagtc tttctctcta ttagcattgg gaccagtgat
    42781 ttttcatggg gaaagctatt tgatttcgac cagcagacct ggctcctctt tcaagagtcc
    42841 cgtctcccaa gaactatcag tattctcctg actgcctcta gtatgagtat ggcaggcctt
    42901 ctcatgcaga ctattaccca aaatcagttt gctgcaccga gtacagttgg aacgactgaa
    42961 gccgccaaac tgggaatggt gctgagcctt tttgtctttc catcggctag tctgacccaa
    43021 aagatgctct tcgcttttgt ttcatccatc gtattcaccc tcttcttcct agcctttatg
    43081 accattttta ctgtaaagga aaggtggatg ttgcctctga ttgggatcat ctatagcggg
    43141 attatcggct cagtcacaga agttatcgcc tatcgtttca atctggttca gagtatgact
    43201 gcctggaccc agggctcctt ctccatgatt cagacccatc agtatgagtg gctcttctta
    43261 ggcctcatca tcctgataac cgtttggaaa ttatcccaaa ccttcaccat catgaatctg
    43321 gggaaagaaa ccagcgagag tttggggatt tcctactccc tacttgaaaa actggccctc
    43381 tttctggtgg cgctaacgac aagcgtcacc atgattaccg tgggtggctt accatttctc
    43441 ggagttatcg ttcccaatct tgttcgcaag cgctatggag ataatctaag tcaaaccaaa
    43501 ctcatggtcg cactggttgg tgccaatcta gttctggctt gcgatatcct atcccgagtt
    43561 ctgattaggc cctatgagtt gtctgtcagt ctcttgctag gaatcatcgg tagtctcgtc
    43621 tttatcctac ttctctggag agggggacga aaagatgcag actaaaagca aacataccaa
    43681 gctcttctgg attctcatta ttcttgccat cggagcttgt cttctctact tttggcccat
    43741 cactcacttg tcagcctttg cttggaagtt gcgttcccaa aagatcatcg tttatctctt
    43801 ggtagccatc gcgactggga tttcgaccat tagttttcaa accctgacgg aaaatcgctt
    43861 cctgacgcct agtattttgg gaattgaatc cttctacgtc ctactacaaa ccctactact
    43921 ggtttttgaa agcaagtttc ttcaacttgg caaatcccct atcttagaat tcctagtctt
    43981 acttcttgtc cagtccttct tctttctcgc cttacaaggt tacttgaaga cactgatgaa
    44041 gcaagacctg gtcttcatcc tgctgatctg tctagcgctc agaagtctct ttcgaaatat
    44101 tagcaccttc cttcaagtcc taatggatcc aaacgaatac gataaactgc aaaatagtct
    44161 ttttgcctcc tttcaacatc tcaacacttc catcctagcc atcggttctc tgatcatcct
    44221 cgctttgaca atctttttct ttcgaaaagc agtcgttcta gatgtcttgc acctgcaaag
    44281 agaaacggct cagatattgg gactcgatgt tgaaaaagaa cagaaagagc tcctctgggg
    44341 aatcgtgctt ttgacctcaa cggccactgc cttggtagga cctatggcct tcttcggctt
    44401 tatgctggct aacctcacct acctgattgt caaagactat cagcacaagt tactctttat
    44461 agtggccatt ctggttggat ttattagctt aaccttgggg caagccttga ttgaacgagt
    44521 ctttgcactg gaaattcgta tcagtatgat cattgagagt gtgggtggct tcttattctt
    44581 tatcttacta tataggaggt ctcgtcagtg aaactggaaa acattgacaa atccattcaa
    44641 aaacaggata ttttgcaagg catttcgctt gaagtcagtc ctcaaaaact gacagccttt
    44701 attggtccaa atggtgctgg aaaatcgact ctcctctcca tcatgagcag actaaccaag
    44761 aaagatcagg gagttctcag tatcaaagga cgtgaaatcg agagctggaa ttcgcaagaa
    44821 ctggcccaag aactaaccat cctaaaacag aaaatcaatt accaagccaa attgactgtt
    44881 gaagaactgg tcagttttgg acgttttccc tacagccgag gtcgacttag atcagaagac
    44941 tgggaaaaaa tccgagaaac tctgaactat ttggaactga ccaacttaaa agaccgctac
    45001 atcaatagcc tgtcaggggg gcaactccag cgcgtcttta tcgctatggt actggcccag
    45061 gatacggact ttatcttgct ggacgaacca ctcaacaatc tcgatatcaa gcaaagcgtc
    45121 agcatgatgc agattcttcg acgactggtg gaggaactcg gcaagaccat tatcatcgtc
    45181 ctccacgata tcaacatggc cagtcagtat gcagatgaaa ttgtcgcctt caaggacggc
    45241 caggtcttta gcaagggaag aaccgatcaa atcatgcagg ctgacctgct cagtcaactt
    45301 tatgagattc ccatcacgct agctgatatc aatgacaaaa agatctgtat ctatagctag
    45361 taacataaaa gctcaagtta gagaaccttc agtctcttag tcaataagat taagagactc
    45421 cctaaatcgt tatcacattt taaaaaggag aaattatgaa aacatccctt aaactttatt
    45481 tcactgccct agtggccagc ttcttgctcc tacttggtgc atgtagtaca aactcaagca
    45541 ctagtcagac agagaccagt agctctgctc caacagaggt aaccattaaa agttcactgg
    45601 acgaggtcaa actttccaaa gttcctgaaa agattgtgac ctttgacctc ggcgctgcgg
    45661 atactattcg cgctttagga tttgaaaaaa atatcatcgg aatgcctaca aaaactattc
    45721 cgacttatct aaaagaccta gtgggaactg tcaaaaatgt tggttctatg aaagaacctg
    45781 atttagaagc tatcgccgcc cttgagcctg atttgattat cgcttcacca cgtacacaaa
    45841 aattcgtaga caaattcaaa gaaatcgccc caaccgttct cttccaagca agcaaggacg
    45901 actactggac ttctatcaag gctaatatcg aatccttagc aagtgccttc ggcgaaacta
    45961 gtatacaaaa agccaaggaa gaattggcca agctagacaa gagcatccaa gaagtcgcta
    46021 ctaaaaatga aagctctgac aaaaaagccc ttgcgatcct ccttaatgaa ggaaaaatgg
    46081 cagcctttgg tgccaaatct cgtttctctt tcttgtacca aaccttgaaa ttcaaaccaa
    46141 ctgatacaaa atttgaagac tcacgccacg gacaagaagt cagctttgaa agtgtcaaag
    46201 aaatcaaccc tgacatcctc tttgtcatca accgtaccct tgccatcggt ggggacaact
    46261 ctagcaacga cggtgtccta gaaaatgccc ttatcgctga aacacctgct gctaaaaatg
    46321 gtaagattat ccaactaaca ccagacctct ggtatctaag cggaggcgga cttgaatcaa
    46381 caaaactcat gattgaagac atacaaaaag ctttgaaata agccacttca aactcaattt
    46441 aatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggttgc tcaaaacact
    46501 gttttgaggt tgcagatgaa agctgatgcg gtttgaagag attttcgaag agtataaaat
    46561 tttgacattc taaaacgcat cctatcaagt tcactcaaac ctgataggat gcgtttttat
    46621 cattttgaaa tctatttacc ccacctcatt ccccttcttg atttcgttta agggaaaagt
    46681 ggtctggaac gggatcctta cctgttttcg accagggatg acaacgtaaa atccgagcca
    46741 agcccatcaa taccccctta aaaccatgtt tttcaatagc ctgaatcatg tagttggaac
    46801 aagtcagctc aaagcgacaa gagggtggaa agactggtga gataaaacgt tggtaaaagc
    46861 gcacaggcgc tattaaaatt cgtttcatta ttttttagtt acagccatgg tgtgtagttg
    46921 gctgatttct tttttattaa gacgacggga ttctcctgga cggagtcctg tcaagtctag
    46981 gtgtccgaaa cgagtccgag acaacttatc tacttggaga ccaacagctt caaacatctt
    47041 tttaacctga tggttacgcc cttcatggat ggtcaactgc accacagagc gatttttgac
    47101 tgggtccact ttgagaattt cataaacagc tggcttggtt ttcttaccat caatctcaag
    47161 accacgggtc aaggggcgga gattgtcctt attggccaca cctttaacac gcgcgacata
    47221 aaccttgtca atctcattac gagggtgaat catctcgtct gtaaagtccc catcattggt
    47281 caaaatcaag acacctgatg tatcccagtc caaacgaccc acagggtaaa tacgctcttt
    47341 gacattgggc aagaggtcga caaccgtctt gcgaccctta tcatctgtca cactggaaat
    47401 cacaccgcgt ggtttgttaa gcagatagta gaccttttct tcgttgtaga taggttgacc
    47461 ttcaacttcg accttgtcgc ctgacttgat agtggttgct agttcacgca ccacttggcc
    47521 gttaaccgtc accaagcctt gcttaatcag ctcttctgct tttctcctac tggccacacc
    47581 tgcgtgggca atatacttat tgattctcat cttcttctat cctttcacca aataattggc
    47641 tttcttgggc ttgaatctca agctcatcaa tcactggtaa ttcttctaaa tggtttatcc
    47701 ccatgtaatc taggaaataa tccgtagtca catagaggtt ggggcgcccc aatacttcct
    47761 ttttcccgtc ttcctttatc aggtcaaaag cctgcaactt tgccaaggct ccactcgagt
    47821 taactccacg gatggcatca atttctatcc gcgtaatcgg ctgtttgtag gcaataatgg
    47881 acaaggtctc aagggcagcc cgagacaagc tctggttgat aggcgcctta gagtattcct
    47941 tcaaaatctc tgcaaattga ggcttggtca ccaatctata agcaccactt gtctcaatca
    48001 aagccaaact ggaatctggg tccttttcat acttctgggc taattttcct aaactttgct
    48061 ggatgcctgt cggtggcaga gagaggagtt cagctaactg gcggacccga atcccatctt
    48121 cacccgctac aaacaagagc gcttctattt ttgctaaagt actcatcttt cctctctatc
    48181 aagtctagct ttgaggcact tgactttctt ccttcttttc catgagatag atatctccga
    48241 aactctcctc ttgcacgagg atcagctcct gggttttgat taactctagg gttgccaaaa
    48301 agagggtgat gacctcttgg acattctggg cttccttgaa caaatcctgc aagcgcaatt
    48361 gatctcgtcc aatcaaggac tctttcacga taatcatcat gtcctcaatc ttatactcat
    48421 cccgcaagat agtcgtgtga ttttgtgcaa actcctcttt tttcttggct aggatatttg
    48481 aaaaagccaa aaagaggtca atggtcgtct tgtcatgcac aagctccgca tcttcgtaaa
    48541 tcaactctgt cggcgctttg gaataatact gggcccgttc ttggtgcttg gcttccaagt
    48601 gctcacccaa gagcttgaac ttgcgatatt cttcgatttg agagaggagg tcctgctcca
    48661 ggtcatcccc caagtctgtc acttctgcta ccttcggaag gagtttacga ctcttaatca
    48721 gcatgagctg actagccatg accatgtact cacccgtcac ttccagacgc atggcctgca
    48781 gggttgagac ataggctaga tactgttcga tgacttccgt aatgggcaca tcgtagatat
    48841 ccatctggta cttagaaacc agatgcaaga gtaagtccag gggtccttca aaatctttta
    48901 atttaatatc cattatctat atttttctaa ggtcaggact gtttttaatc ctaatttttt
    48961 tgcaatttcg tacaaatcga ccttgttttc tatttgtctt agaataaact gttcacgtaa
    49021 gacttgagct gataaggatg gaaaaccttt ctccttgaca aaagattcta actgacgaaa
    49081 ggcccactga cgagaatagg gtttctctcc tctttcaaaa agataggtct gccccatcaa
    49141 gggttccaat tctgaaagca aggccgtggg aatggtgaca atcctctgtt gggaagcctt
    49201 gctgattcgc agcacctgaa aatccagatt gatgtccgca accttgatgg ctaaaatctc
    49261 actgggcaag agccccattt ctaggattaa gagcgctagc aagcggccct ctggatggtc
    49321 gctttcctgc caaaaagagt ctaggtatag aatctctggc ttttccgtct tcttttcagc
    49381 ttgtttggct aattccaagc ggtaaaagct gtccacctct cctttttgat agagaaagta
    49441 gagaaattgg ttacaggccg aaatctttcg cttctgggcg ctgattttta gattggctag
    49501 ctgggcttgg taaatcttga gactggtctc agaaatccgc tcacctacca tgtctaaaaa
    49561 ttgctccaaa tcatacttat aggactgctt ggaattgaca gacaagccct gcttttcctc
    49621 taaaaaggct gaaatcctgt ctctcattgg catcgaatct catattcctt actaaagtca
    49681 tgcaagaggg cattaacggc cttgaggatg gacttgcgcg taataatccc ttggaaaata
    49741 ccctctgcat ccacaaccgg taagaaggac tcatctacta gcttgtgcaa gacctccgta
    49801 atggtgaaat caggcgaaac aaccgctacg tccgtttttg tcatatgaac gatatccgta
    49861 tccgccatga tttcttggct caagtcatgc tccatctgat aagccataat atctctgagt
    49921 ccaatcgtcc caacaaactg tttttcatct gtcacaacgg gaacacgggt ataggtcatc
    49981 tgactgagca agagggtcgc atgatccgca ttgtgggtat caatcaacac agctagattt
    50041 ttagcagggg tcaaaaaagt ttcctcctgc cccaacaaga aagtctcaaa ctccttggca
    50101 atcatcgact aaactccttg gacaaacctg gatacacctc gtgatctcgt gtcaaaaagt
    50161 ccactttgaa gtaactatca tcaatctcca cacgagcata gagacattct ctgatggtac
    50221 ctcgtggttg gctgatagaa cctggattta gaaagaggat cttgccttcc atccaagcac
    50281 ttggcacatg caagtgacca tagaggcaga tagcggcctc ttcctcctga gcccagtagt
    50341 ccaacttttg aaagttgaaa ttgatgtcaa acaagtgacc atgagtttgg ataatcttgg
    50401 tcgaaccaag ctcagtcacc agacgttctg ggtagccggc gtagaagtcc atgttccctt
    50461 taacaacgcg gatgccctcc caaagtggag aatccggacg tagttcagaa tcgccgttat
    50521 gaaaaacggc atcgactttg cccacatagc gatcacggac ttcttccaca atcaagctat
    50581 cgccatggga atcgctcatt acaatgatgg tttgctttgc catgatggaa atacctccaa
    50641 aagtttctta acggctaagg cacggtgaga ttgactattt ttttcttcca gggttaattc
    50701 agctgatgac tcacctgttt ctcctacaag gaagagggga tcatagccaa agccattttc
    50761 acccttaggt tcaaagttaa tataacctga ccagtctgct tcaacaacta aactttcctt
    50821 atttgggctg gctacgacta gggttgtgtg gaactgagcc gagcggtcct tgagttcaaa
    50881 gaccatggcc aattcgtgca agagtttggc attattttca cggtcagttg ctcccacacc
    50941 tgcgaaacga gctgaccaga cgcctggtaa gccaccaagg acatcgactt tgagaccaga
    51001 atcatctgcc aaaaccatct tgcccgttaa ttgagaaatg gtttctgcct taaggcgggc
    51061 attttcttca aaggtcatac ctgtttctgc tacttcaggc aggtcagggt agtcattaag
    51121 attttccaca tcgtagccta acttatcaaa gatagctcgg aattccttgg ttttaccttc
    51181 gttacgagtc gcaatcaaca aggtttctct gaccttgctt gtctcaaaga aatcatgaac
    51241 attgacccct tctttaggca attctacata caagagttgc ccattttcaa ccaagagcag
    51301 ggccccatga cgttgaataa cttccaagtt tcgtcccatt tcttgattaa gcatgtctac
    51361 cacaaaggag aacaaacggt aggtagaacc atagcgtaaa acagtaactg aaagcgggaa
    51421 accatactct tcatctccaa atattttgga gaattcaaac agaggaaaat ctgtcttata
    51481 gtcgctcaaa ctgttaacgc caccaaaaat actataagac ccaacatacc agtcctggtc
    51541 atccttatat tcataaattt tatttgtcat aattctacat gctccacatg aatctctttt
    51601 tccagccatt cttcaccaat ttgtgcaaaa ctttggctac tggctgttgt gtaaaaacgg
    51661 tgatggagtg gtccagcatc gcgaccacga ttgatttcaa aataattgag taagactgag
    51721 atatcccgta cgcactctgc cccactatcg atgagctgaa cctttggccc catcacattt
    51781 tggataatag ggcgaaggag tggataatga gtacagccca aaatcaggct atccaccttt
    51841 ccaaccaagg gacgcagggt ttcatagacc accttcttgg taacactggt tgacagggca
    51901 cctgactcaa ccaagggagc aaacttggga caggccaagc tctccacctg taagtcggga
    51961 tccagatcat ggattttctg acggtatatg tctgattgta ccgtcatggg cgttccaatc
    52021 actccgattt tcccaccttg actggacttg atggctgccg aagctcctgg caaaattaca
    52081 cccaagacag gaatatctag ttgagccttg atttcttccc agacgaccgc agtcgcagtg
    52141 ttacaagcaa tgacaatcat tttgacatcc ttagtcaaga gaaagttgac cagctgccaa
    52201 gtatattcac gaatttgctc agcaggacgg gggccatagg gcgcccgcgc cgaatctcca
    52261 atatagacga tttcttcatg gggaagctgg cgcatgagct cgcgcacaac ggtcaagccc
    52321 ccgacacccg aatccaaaaa accaattggt cgattatcca tacagtcttc tttctagtct
    52381 tttttctgat tgatcgttca ttatgattcc ttgtactgaa cgaactgacc gacagcttga
    52441 tagaatgtca actacctctc tcttaatcat aatcaaatat caatagaatg caaggaaaaa
    52501 gtctcatccc taaaccataa ccaacatagt gagaagtctg gaactttcat cccagacttt
    52561 tccttattta ttttttcttt ttattgttag caagggctgc cttttgttgg cggatgattt
    52621 ggtggtaaac ttgttgtacc ttagcttcgc ttggtttttg accatttgca ctcaaaagag
    52681 tacgaactgc ttcagcattc aaacgtgggt tgtcagcaaa ttctttttcg atttgcttac
    52741 gaaccaagta cattcctcca agagctcctc ctagaaaagc tagcacaatc aatacaattg
    52801 ctaaaagtaa atccatcatt tttctcctgt ttctttttga gttcctttca ttataccaca
    52861 aactagccac cctgaccagt ttgttctaca ctttcaggga tggaatagac agcaaaaaga
    52921 accctgcttt tctgaaaaag aggtctcctt gctaagttta tactcaatga aaatcaaaga
    52981 gcaaactagg aagctagcca caggttgctc aaagcaccgc tttgaggttg cagataaaac
    53041 tgacacggtt tgaagagatt ttcgaagagt attaatttac ataaatagcc agtgtttgat
    53101 agggtttgag tagaattttc tcagacactt ctgcatcttc atagtttgat atcaaaatct
    53161 gtccattttg gtagactgct ggcaagtcga tttccacttc tttagcataa aagttattga
    53221 gcactagtaa cttttgatcc tcaaactggc gttcaaaagc gtagacttgt ttgctatctt
    53281 caaaggctgg tttgtaactt ccttctgaaa tgattggcat ttccttacgc agtcgaatca
    53341 agtcttgata gaaggtaaaa atcggaccct ggatttcatt ttctacattg atgtatttat
    53401 aggatttacc agctttcaac caaggagtgc ctgttgaaaa tcctgcattt tccgaagcat
    53461 cccactgcat gggaatgcgt gaattatcac gcgacttagc ttgaataatc tggaaggctt
    53521 cttgctgact ctttccttct tctaagagca tctgataggc attaagcgat tcgacatcca
    53581 cataatcagc catagaatca tagtctgggt caatcatccc gatttcctca cccatgtaga
    53641 tataaggtgt cccacgtgac aggtgaatgc tggctgctag catggtggct ccttccttgc
    53701 ggaagttttg aatatcgaca aaacggttca aggcacgtgg ttgatcgtga ttgttccaaa
    53761 agagggcact ccaaccgtct ttatcactca tttccttacc ccaactatgg taaagactct
    53821 tcaactcttc aaaatcaaag ggagccaagg tccacttttg tccatcctta tagtccacct
    53881 tgaggtgatg aaaattaaag gtcatggata attcctgacg atcaggcgac gaatagagga
    53941 cacagttttc catggtggta gaagacattt ccccaactgt cataaagcta tcgtcagatc
    54001 caaaagtggc ttggttcatc atacgcaaat agttatgaac gatgggtttg tctgtataag
    54061 ctggcttccc ttcattttca ggacagtcca ctgaaacctc gtccttaccg atcaaattga
    54121 tcacatcaaa tcggaaacct ttgacaccct tgtcgcgcca gaaattaaca accttgaaaa
    54181 gctccttacg gacattggaa ttgcgccagt taaggtcagc ctgggtctca tcaaataggt
    54241 gaagatagta tttcccagta tccccgaaag gcgtccatgc agaaccacca aacttagact
    54301 gccaatctgt tggttggtct tggatgaaga aaaagtcttg ataatactta tcaccagcta
    54361 gggctttctg aaaccattca tgctctgtcg aacaatgatt aagtaccatg tccagcataa
    54421 agtcaatctt gtgctcttta ccgacacaca ccatttcctc aaaatcagcc atatcaccaa
    54481 aaagaggatc cactgccata taatctgaaa tatcgtaacc attatcccgt tgagggcttg
    54541 gatagaatgg attgagccag accatatcca cacctagttt ggctaaatag ggaatttttt
    54601 cgataatccc acggaaatcc ccaataccgt tttcagtggt gtctttgtaa gattttggat
    54661 agatttgata gactactttt cctttatcaa gtgtcatctg tttctccttt tctgataaaa
    54721 gggaggaagc agtcttccgt ccctatttgt gctatttcaa ttatactcaa tgaaaatcaa
    54781 agaacaaact aggaagctag ccacaggttg ctcaaaacac tattttgagg ttgcagatag
    54841 agctgacgtg gtttgaagag attttcgaag agtattagat tcgtgtagcg accatgagag
    54901 atgctccagc ttggatcgtt gtcggataag ttccgggaat agtcgctgta taagcatctt
    54961 ggttggtgat gataacagga gtttctgtca ccagacctgc agccttaatg acatccatat
    55021 caaaacgaat cagttgctga ccaactgtaa cgtgatctcc ttggactaca agactttcaa
    55081 aacctttgcc atcaagacct actgtatcca taccgatgtg gatgagcaat tcaactccct
    55141 cgtcagagac aatgccgatg gcatgcttgg tagggaaaag aaccgtcact gtcccattaa
    55201 ctggagaggt caactcacct tggcttggtt caatgactag accttgcccc atgacacctg
    55261 atgcaaaaat aggatccgtc gcttgactca attctttcac ttggccagtt agtgggctga
    55321 taatttctac cgaagtaagt tctactggtt catggttcac aaattctgct tcttcttgag
    55381 caacgaattc tgcctgcaag ttcgtatcgc cctctgtttt tgtaaagaga ccagccttgc
    55441 ggaagaagaa agtcaagagc attggaacaa caatcgcaac tagcatagtt cctgcaaatg
    55501 gcagcatgta ttgaggttga atagagagaa tacctggcaa accaccgata ccaatagaag
    55561 ccgcagttac attaaaagta acggataaca tgcctgcaag ggctgaacca gtcatcccag
    55621 caacaaatgg ataaatatat tttacgttaa ccccaaaaag agctggttct gtaacaccga
    55681 gataggctga aatggttgca ggaagtgaaa cctgagcctc acgctcatca tggcgatgca
    55741 tgaaataata ggcaaacacg gctgagcctt gagcaatatt agaaagagca atcattggcc
    55801 atagggcagt gccaccagca tccgcaatca attgtgtatc aatggcattg gtcatatggt
    55861 gcagacctgt gatgacaaat ggagcgtaga gggcaccaaa aattgcaccg aagagccatt
    55921 taactggacc agttaaacct gccaagacaa ctgatgaaag tccttgtcca attgtccaac
    55981 cgattggtcc caaaacagta tgagccaaaa tcaaggctgg aatcaatgac aaaaaaggta
    56041 caaaaatcat ggaaatgact tctgggatat gtttgcgcca gaaaatttca agataagaca
    56101 gactcaaacc tgcaagcaag gctgggataa cttggacttg gtaaccaata cgattaacag
    56161 taaaataacc aaaattccaa acccagtttg ccgcgatatc agctgctggc gttgaagcaa
    56221 ccgcataggc attgagcaac tgaggcgata ccaaacagat tccgagaaca attcccaaaa
    56281 tttggctggt tcccatctta cgagaaacag accaagtaat ccctactggt aagaactgga
    56341 agatagcttc accaggcaac cagaggaagt gattaacccc tgcccaaaac tgagaggatt
    56401 ctgtgatggt cttgccatcc aacatcgacc aatggacacc ttccaagaca ttacggaaac
    56461 cgaggatcaa tccaccaaca atcaaggctg gaataatcgg agtaaagatt tccgccagag
    56521 tggtcataac accttgaacc acgttttgat tactcttagc tgcagacttg gttgcttctt
    56581 tggaaacacc ctcaatacct gaaacggctg taaaatcatt ataaaagatg ggcacgtcat
    56641 ttccaatgat tacctgaaat tgacctgcat ttgtaaaagt tcctttaaca gctggaattg
    56701 actcgatagc tttaacatta gccttcttat catctcttaa aacaaagcgc atccgtgtcg
    56761 cacagtgagt tacggcagtc acattttctt tgcctccaat tgcctgaagc agatctttgg
    56821 cttcttgttc aaattttccc atttgattct ccttatactt gtcaaagcaa gtttgatttg
    56881 ataagtatat tgtaaacgat accaaacttg tctgcaactt gtttggtata aaaagggtgt
    56941 ttttttgtaa attttctagc acttgtatgg taaaatagat acaggtgttc attaaactag
    57001 actaaaaacc tattaaagca ggcaaaatga agaaatacca acaattattt aagcaaatcc
    57061 aagaaaccat tcaaaacgag acttacgctg tcggagattt ccttcctagc gagcacgacc
    57121 ttatggagca atatcaagtg agtcgtgata ccgtccgaaa ggccctgtct ctcctccaag
    57181 aggaaggatt gatcaaaaag ataagagggc aaggttctca agtcgtcaaa gaagaaaccg
    57241 tcaatttccc tgtatccaac ctaaccagct accaagaact agttaaagaa cttggactgc
    57301 gctctaaaac caacgtggtc agtctggaca agattattat tgataaaaaa tcctcactga
    57361 taaccggttt cccagagttt cggatggttt ggaaggtggt ccgccagcgt gtggtggatg
    57421 atctggtatc cgttctggat acggactatc tggatatgga actaattcca aatctcactc
    57481 gccaaattgc tgagcagtct atctattctt atatagaaaa tggcctcaaa ctccttattg
    57541 attatgctca gaaggaaatc accatcgacc actcaagcga ccgagacaag attctcatgg
    57601 acattggcaa agacccttat atcgtttcga ttaaatcaaa agtctatctc caagacggac
    57661 gccaatttca gtttaccgaa agtcgccata agttagaaaa atttagattt gtagattttg
    57721 caaaacgcaa gaaataaaag attgagacac cagatctcag cctttttctt tatcccaaaa
    57781 ctaattcatc actgaccaga ctttggccac tatttttctg gaagagatgc ataaggtctt
    57841 caactgtcag atgctttttc tcttctccct tgacatccac cactatcttg ccttgataga
    57901 gcataatgag acgattgccg tactcaatcg catgattcat atcatgggta atcatcaaag
    57961 tcgtccactg atggtgctcc acaatctttt gcgtcaagtc catcaccatt tgactggttt
    58021 tcgggtcaag tgccgcagta tgttcatcca aaagtaaaag tttgggtttc accagagctg
    58081 ccatgactag ggtcaaagcc tgtctttgtc ctcctgagag atattgagta tctactttta
    58141 agcggttttc aagaccaata ttcaactcct tcaaggcctc ttggaactgg attctatcct
    58201 tctccttcac accccaacca agtcctctct tttgcccacg tctcaaggca atagccatat
    58261 tctcctcaat cgtcaaacga gaagctgttc ccatcttagg atattgaaaa acacgggcaa
    58321 tatccttggc tctctttctg acactcagat ttttaatgga tttccctgcc agtagaaggt
    58381 ccccttcgtc caccgataga ttgccagcca agatattcat caaagtggat tttcctgctc
    58441 catttccacc aatcacatag ataaaatctc cctcttcaac ctctaaatct aatcctttga
    58501 ggacatggtt ctcattgacc gtccctgctt caaatgtctt gtgaatattt tcaagtgtta
    58561 acaaacttgc cataactttc tcctcctatt catttctcaa tttcagacca cgaatcttta
    58621 atctcttttg caattctggt gcaaataaaa ccaaagcgag caagattgca ttaaagagac
    58681 gtaccaagtt ttgatctaga tttggaattt catagatatt taaaataatc aaacggtaaa
    58741 caatagcacc gattccgatg gataataagc ggcctccaat ggtcaagtcg tgtatcaaga
    58801 cttccgagct caaaccaaca acaatggttc ctgtcccaga agtcacatct gaaaatccat
    58861 cattttgggc aaacaaggaa ccacataggg caatcaaacc gtttgaaatc atgtaaccaa
    58921 caatcttcat ggtgtctaca ttgactccat tggcctcact tatcgggata ttatccccag
    58981 tcgaacgcaa gaccaaacca atctctgttt tcatcaaaag ggtcaagacc aaacaagtaa
    59041 gagacagact aaactaagtg agaaaacagc tccttcattt gtcagaccca agctcgccaa
    59101 ctgtttaaag acggttgcag aatctcccaa ggaaagattg ggtacactgc ccataatttt
    59161 aatattgatt gaatagagcc ctgtcaaggt cacaatccct gtcaagagag ctgggatttt
    59221 catcttggtg tggagcattc ctgatacaag acctgctacc atacctgcca gcaaagcaag
    59281 taaagtcgca agccaaggat ttgcccctgc ctgtatctgt gatacaacga ctgctgcccc
    59341 cagaggaaag gctccctcag cagttatatc cgcaatatcc aaaatacgga aagtcaagta
    59401 gaccccaatc gccacaatcg accacaacaa accttctgat aaactagata acacaaaatt
    59461 catcttaatc ctccttattc cttgccttct aacttactaa tatcaattcc caatgcatct
    59521 gccatttctt gattggtatg caattccagt ttttcaggca actcaactgc tatattttct
    59581 ggtttctcac cttttaaaac acgaatcagc atgcgagctg tctgtcttcc caattcttca
    59641 taattggttc cgtagttata caagtcacca acagcaatca tttctgttga accaccgaat
    59701 actggaacct tgtgtttaat agaaacctgc ttaactgttt ccatggttga cgaaatgata
    59761 ttatcagttg ggacaaaaac catatccacc tctgccatca aactctctgc tgccgccttg
    59821 acgttattac tgtccaagat tgttttttca acaacggtaa agcctttttc tttcagaagt
    59881 cgcttagctt catcatttta aacaaccgaa ttgggctcgc tctgagtata gaggattcca
    59941 atcgttttag cctttggcaa cactttcttt atcaaattga tttgggttga aatggcatct
    60001 gatgactgat cgcttgtccc agttacattg cccccaggat gttctcttga ctcaaccaac
    60061 ttggcactga ctgggtctgt tacagctgaa aagataactg gtgtcgtttg cgtcgtattg
    60121 gccaagctct gagcagaagg ccttgcgatg gctagaacga catcgctgga ttctgctagt
    60181 tgctgggaaa tcgtttttag atttctttgt tctccctgta cattttgcaa atcaatctca
    60241 atattttccc cctcaacata gccttgtttg gccagctcat ccacaaattc ttctctagta
    60301 gcgtctaagg actggtgggt aataaattgc gaaataccga tacgaaagac atctttttct
    60361 tatctgcctt caactgatgc aaactgatca gagaagtcaa gaggagcccc actaccaaga
    60421 gggggctagt gattttcgaa caactttcat aatgaaactc cttctcagaa aagataaaac
    60481 aaaaaaccgc ctagatacta tctaaacgga tacttgaaat aacctaacaa gttacaactt
    60541 agctagtcca tttagatatt catctatatg gaccacaatc aaaaatctta gccacataga
    60601 tacaaacaaa ttgcttgaac tgtttgcatc catggtgaca tgtctacaaa cactatctaa
    60661 agtagctaaa gtaaaagttt tgattcatag ttacggcttg tctcttattc atttcttttt
    60721 ctgctttctt ttttgatgct tcctatccta ccaccttttt catcacctgt caataatatt
    60781 tcagaatttt ttaaaatttt tcgaaaattc tttcaggaag ctttcaaagt ttttcaaatc
    60841 agtccaacaa aaaaagtttt ataatttcca taaaaattga catggaaatt ataaaaccat
    60901 tattagttta gtcctttttg ataacgtgct aattcggctt ggttcgccca aacatagtga
    60961 cctggacgga tttctaccat agatggctta tcagtctcat agtcgtgttg acttgggtcg
    61021 taaaccttca agaccttctt acgttccaag attggatctg ggattggtac cgctgaaagc
    61081 aaggcttgag tatatgggtg aattggattg ttaaacaatt cttctgtttc tgcaacctct
    61141 acaataacac ccttgtaaat aactgcgata cgatctgaaa taaagcgaac aaccgacaag
    61201 tcatgggcga tgaagagata ggtcaagccg agctcttttt ggaatttttt gagcaagttc
    61261 aagacttggg cacgtacaga aacgtccaag gctgaaattg gctcatctgc aataacaaag
    61321 tctggttgca tgaccaaggc acgggcaata ccgatacgtt gacgttgacc gcctgagaat
    61381 tcatgagggt aacgagtcaa gtgctcagca agaagaccta cttcacggat aatactttga
    61441 actttctctt tacgttcttc ttcatcctta aataaacggt gattgtaaag accttcagaa
    61501 ataatataat caacagtcgc acgttcattc aaacttgcgg cagggtcttg gaaaatcatc
    61561 tggattcgac gaatcaattc cgcagcttgt tcacgcgatt tcttaccatt aatcttttga
    61621 ccatcaaaaa tgatatctcc attacttgta tcatttagac cgatgatagc acgaccaata
    61681 gttgttttcc cactaccgga ctcacctaca agcgagaaag tttctccctt gttgataaag
    61741 aagttagcat ttttaaccgc gacaaacttc ttacttcctt caccgaagga aatttctaaa
    61801 tctttgattt ctactaattt ttcagacatt tccttcctcc tagtcagcca gatgggcaaa
    61861 tcccattttt tcacggatct tatcatggag atttgcaatc acagctggtt tttctacttt
    61921 tggagcatcc tcatgaagaa gccaagtttt agcccaatgt gtctctgata ctgagaattg
    61981 aggagctttt tgttcgaagt caatctgcat tgcgtagtca gaacgcaagg caaaagcatc
    62041 ccctttcagg tcagtataaa gtgacggagg tgttcctggg attgagtaaa gatccccttt
    62101 atcatcagca agctgaggca agctagacaa gagactccat gtatatggat ggcaaggggc
    62161 atagaagact tcctcaaccg ttccatactc aacgatttcc cctgcataca taaccgctac
    62221 cttatccgca atacttgcca ccacaccaag gtcgtgggta ataaagattg ttgtgaaatg
    62281 atactcgttt tgtaaagatt ttagcaaatc aataatctga gcttgaatag ttacatccaa
    62341 ggcagttgtt ggctcatcac agatcaagac atcaggtcgg caggcaaggg caatagcaat
    62401 aacgatacgt tgacgcattc ctccagaata ttggaatggg tattcattaa aacgtctatc
    62461 tgcgtctgga atgccaacct tattcatgta gtcaatggcc aattctttcg cttctttagc
    62521 tgtttttcct tggtgtttta caataacttc tgtaatctga ctaccaattg ttttaatggg
    62581 gtccaaacta gtcattgggt cctggaagat agtcgcaatc ttagcaccac gaatttgttc
    62641 ccaatccttg tgagaagata aagctgtcaa gtcctgacca cggtagtcaa tactaccttg
    62701 ggcaatgcga ccattttctt cgagcatacc tgtgaaggtc tttgtcaaaa cagatttacc
    62761 tgatcctgac tcacctacca aggctaatac ttctccttcg actagttcaa gggaaacgcc
    62821 gcgaatggct gtcaatactt tgtcacgaac gtcaaattcc acgacaatat cgcgagcagt
    62881 caaaattaca tttttttctt ttgtcatttc tactcctatc tatgtgtacg tggatcacta
    62941 gcatccgcta agttttgacc aactacgaaa agggacaagg ataccaagac aagggttgtc
    63001 aatggaatcc agaacaagta agcattggtt gttacgtttt gtgaataatc cgaaatcaaa
    63061 cgacccaaac ttggcactgt aatcggtaat ccaagaccga agaaagacaa gaaggcttcg
    63121 tatgagataa agcttggaag catttgagtc atggttgtca caataacaga taccaattga
    63181 ggcatgatat ttttggcaac aatcttcaag gttggtgttc ccaaagtacg tgacgccaag
    63241 ttgtattcca agtcacgata gcgcaagatt tgcacacgga tcatgaaggc aataccaatc
    63301 catgttgtta cgctcatggc aaaaatcaga ttccagaatc cagctccgat tgagtaagtc
    63361 aagacaataa caatcaaaag aggtgggatg tttgagatga cgttgtaaac ttccatcatg
    63421 acacggtcaa ctgattttga aataccccaa ataccaccga caaaaacacc gataaccaag
    63481 ttaatcactg tcgcaatcac agaaatgagg atggagttac gagctccgaa ccagacaccg
    63541 tcaaagagcg atttaccgtt actgtcagta ccgaaccaat gctccgcatt tggcttgata
    63601 taacgaacac taaagtcgtt taccttgctg acatcattga aatcaaactt agaaaacatt
    63661 gggtagatga aacttatcaa aatgatggct accaagattc ccaacatgac tacagttgat
    63721 tttttcttca taaattgttt aaacactgat ttccagtaag aatatgctgg cgcatcaata
    63781 gtttcagagg caaaatcgtc acgttttaca aactgaaatt tttctttatc gattgtagac
    63841 attatttgcc tcctttctca gtcaatttaa tacgtgggtc aataatagtc atccaaatat
    63901 ctcccaaaag acgtgagaag atagaaatac atgtaaagat gaagacaaga ccaacgacca
    63961 tagagttatt agatgctttt acagagtcaa tcaacatttt acccatacct gggaaggcga
    64021 agactgtttc agtaagggtt gcaccaccga taaccccaat aatggcacca ggaattcctg
    64081 aaaccagcgg aaccatggca tttttaaaga tgtgtttgtt tgaaatttct ttttcagaca
    64141 aaccttttgc acgagcgaaa cgaacaaagt cttgagattg caagtcaatc atgtaacgac
    64201 gaatccaaat ggctgtaaca ggagcaccca acaaaccaag gatgactgct ggtaaaacgt
    64261 aagaacgcca atctccagct cccaagatag ggaatgaatc tggaagggca atagatgatc
    64321 caatcaatcg aacgatgtaa accaaggcaa tcgttggaag agcaagcaag aaggtcaaag
    64381 tccctgttga taggctatca atccaagtgt tcttgaaacg agccatggct gaaccaagtg
    64441 gcacggcaag agcataggca agaaccaaac caatcaaacc agtaatagca gagctgacaa
    64501 tcatagatgg atattggtaa ttactttcag tcgctgtata aggatcatct ttcccatagc
    64561 tagctacttc acgagagtca gcctgactag gtgacttgta ggttcttgag taaatattta
    64621 cagaagacgt tttcttacct gttgggaact gaacttgggc agttttggtt tgtccttgac
    64681 cttgagtaat aacctgaaga actggtgtat tagcataggt tgggtaagag tcacctaaat
    64741 tcaagttcac aaagttttga tgaacaaatg ggaactgact gttaaagtac aagagatatt
    64801 tatgtttagt tcctgaaccg accaatgacc atccgatagc tggatcattt tcaaaacgaa
    64861 ggtagcgttt caagtctgga ttttcagggt cttggatttt atttgtatgg tcaatgtcaa
    64921 tcaagttagc atagaagtga aaaacacgtt caaaaattgg aatttcacga gtagcataga
    64981 attgaccact ttcagtaaat tctcccaaag tccaaccatg acctaattga ttgatgtact
    65041 tttcataaat agctttattg gtcgcatttg cttctactgt tacagaagaa tccatgctac
    65101 ttgccttttc ttgcaactct ttagtatcgt aatactcaat gtagcccata cgctcaaaca
    65161 cagtattttc atagttatca cgtttatcag ccgttgtcgc aattttatta tagttaggat
    65221 cctgcttgaa aatcaatttt cgaggaacca aggtatagat aatcgtgtag gtcaaagtcg
    65281 ttactaagaa aatcgaaacc aatgaccgca aaacacgcat aaaaatatat tttttcatat
    65341 tatttccttt aaaaatccca aaagaacctt ctcctcatgg agagaaagtt ctattagaaa
    65401 ttatttactt cacatgactt gccaattctt tttgagcttt ctcatttgat tcagcttttt
    65461 ctttcaacca tttttcacga gctttttcat actcttcctt agtcaccact ttatcttgta
    65521 atttcaaata tttgaagtaa acatctgacc ccttagagcc tgtttgcgca gaagctccag
    65581 taaatggaac aattcgtgaa agcactggtg ctgcaccaga agaagccata gcaggaataa
    65641 agagtgaact atctgtcaac catgcttgag ccgctgcata tttttcataa cggacattca
    65701 agtcgcttgt ctctctggca gcttcatcaa ctaatttatc gtattctttc aaaccaactt
    65761 gaactactga agggctattt ggattatcaa atcctaaata tgtttttgta gtttcactgc
    65821 tagttgtttt taaaatatcc aggtaagtag atgggtcttg atagtctgga ccccatgaaa
    65881 ctcctcctga tacatcccaa tcctcagatg aagcattggc agcatagtaa gtaatattaa
    65941 ggaattcatc acttgtcatt tgttgaatat caacaacgac attttcaaca ccaagaactg
    66001 tttctacaga ttgtttaaag gactgaatac gagatatgta gttttttgat gcttggtcta
    66061 ctggaacgtc cagatgaata ggaaactgaa cgccgtctgc ttctaaagct ttcttagctt
    66121 tcgcaaactc tgccttggcc ttgtcagcat tgaataaacc atcctgccca tcagctaaat
    66181 tcacaccttt ccactcatca ccataagcag gaagttgagc agcgactaaa tcaccaaagg
    66241 tcttctcacc agctgaaaca aagtctggtt ttacaaataa attacgaact gctaaagctg
    66301 ctccatcttt accattgatt tgagctgagt aagctgagcg atcaagagca aaattcaagg
    66361 cttgacggaa atctttgtta agcaatgcct tcttagtagc tactttctct gaatctgtag
    66421 ttttagaagt atagttgtaa ctttggcgat caatattcac acccagacca gcaatcccag
    66481 agcctgattg tgtgtaatag atattgtcct tgtattcttc tgcaacctta gaatagttgg
    66541 agctggtagg gtaaagacgg gcataactat aagctccact agtgaagtta cgctctagcg
    66601 actcctgatc tgatccatca tagtaagcta gattgatagt atctaggtgg acattttctt
    66661 tatcccaata ttgctcattt tttacaaact ctacagaaga ttttgcagtc aaccctttca
    66721 acaagaatgg accattataa agcaaggatg tcggatctgt tggtttagca aaatcgcttc
    66781 cttttgatgt ttcgaattct tcattcagag gccagaaaat agaataggtc aacttagagt
    66841 tccagaacgg ttcaggctgg ttcaaagtgt attgtaacgt ataatcatca accgccttga
    66901 caccaactgt tgaaaaatct gttgaagttc ctgatagata atctgccaag cctttaaccg
    66961 aattttcagc taaatacata gcttctgatt ttttatctgc tgcgtgtttt aaaccgttca
    67021 cgaaatcttt agccgtcacc tctgcatatt cttctccatc agaggtaaac catttaaccc
    67081 ctttacgaat cttataagtg taggtcaaac catccttaga gacttcccaa tcctctgcaa
    67141 ctgcaggagc aagattaccg taattatcgt tagtgaataa accatcaatc ccatttgaag
    67201 tcactactgt tgtactattt ttacttgaaa tcaggtagtc caaggtttct gggtctgctg
    67261 tataaacata gccataagct ttaggggctg atgaatcaga tgattttgaa gaactgcatg
    67321 ctgcaagtac acctgctgct aataaaacaa gacctgctgt agcaaataca cgattttttt
    67381 tcattttcta ctcctctgtt tatgtgaatt atagattgac aaccattata tcacattatc
    67441 cattaaaaat caaacaaatt ttcagaatat ttaggcttgt tggcacaaat ttttcatttt
    67501 ttttgaatat atgattcaaa ttgtcgttcg aagtgtcaaa gactacagtg aaaataggaa
    67561 atttgacgca gaaactttgg agtttaggaa gacatacagt aaaatgaaat acggacggaa
    67621 caatgtgatt ttggaattca aattaaatta taacaatatt gtagaagtat cattctagta
    67681 ttcaagattc agtttactat gtcttttcac accaacctta ttccgaattc aattactttt
    67741 gtgatttaca tatatagatt aagactatct tttatacttt aaaatttctc gctaccttat
    67801 ccactatatg ctcctcgcta tcacgtttct attcatagcc tacgatttca ctattgcttt
    67861 ctctgacaat tcttatttcc tgcgtcagac ttaaaacgat ctatccccag accattttaa
    67921 tccgctacct cacgacagtc aggcttgggg agcgctattg tattcaccgg tagtggatcc
    67981 ctacagagga cttacacctc agatgcacga catgcccata gtataaaaaa atctcctacc
    68041 caaggtagaa gatttcaaac ttataaaact taatccgtca tgtccgatac caacattcga
    68101 tgctccaatg gaatactgca cataactagc aagaaaataa agcctgactg aatccagaag
    68161 agagccaagt caaaaattcc gtgcacagca accactgtaa ggaaagatag ataaaggccg
    68221 ataatcggac gtttccccga ctcctgactc atatccatca tcaagcgaac aggagcaaca
    68281 gaagacaaaa ctaataaaat ggtacccaca attccgtaac tcagaatcgt atcaatataa
    68341 agactgtggg catgttcatg ataaggagca tgtatccgag gataagagtg catataggtc
    68401 aatggccctt caccccaaaa aggattttgc ttaaacaagg ccatcccagc atcccagata
    68461 gaaatgcgtt cttccataga agagtctaaa gtacccattc gaactcccaa atcactagaa
    68521 aagaggaaac tcaaaccaat cgcgaagacc ccaatactaa gccaaaaggc cttccagttt
    68581 ttaatagtcg taaagagata gataattgct ccagcgataa tagcaggaaa ggcagttcga
    68641 ttttgagtaa agttcaaacc aaagagatta acaaagcctg caatcacaca gaatactttc
    68701 aaccaattca acttggtcgt tgtaaacaga tagaaagcaa tcataataca gaaacaacaa
    68761 ataattccat aataattagg attaaagaag gtcacttctg cccggttctg atgccacacc
    68821 tgcatattgg gtgaaagaaa agcatagtta aatttcttca caatttggaa atgttctaaa
    68881 ctggcaaaag cagctgacaa gacactacca aacaagacga actgcaaaat caatcgaaag
    68941 aatttatggg ataaaatcga ctgatagtgc aaaaagaaaa tagtaaatag aaacattcct
    69001 actgaagcca caagacccat ccaattttgt gcaagaatgg atataacagt actatagcta
    69061 agaaaaagaa gcagcatcgg atgctccccc attttctgaa gaatactttt catgtctcct
    69121 gtaaaaatca aactgataat atataaacag agtacaacta caaaaagata aaagggtaaa
    69181 aagatactta ggataattcc caataaaatc agctctttac tagacaaccc cttcagcttt
    69241 tcaataaagc ctattgattt caaaatgaat cctttctctc caaatcagct gattcagata
    69301 atagtaagct atcctatatt gtaccacttt tttagcaatt tgaaaacaaa ggaaacgttt
    69361 tccaaaataa aaaccctatt ttatccacca tatcaaggct tcaaaatgat acttcaactc
    69421 cattctcaat tacccgataa gtctgatttt gcaaatcaat ttctactact gctgttacgg
    69481 acttatcttt attttgacgt ttgattacaa tgctgtgagc tgttggtgtc tctatctcag
    69541 tagtcccttc tagatcaaag gcttctgaac ggttacggaa agaaaataga ttgagaaggg
    69601 ccttcacaac aggtcgttgc acttcttttg ctatttcctc gttgctatag taatgacgat
    69661 taatatttcg accttcttta gtttcttcta ataatttcaa gtcattcttg cctgctaata
    69721 gacccacata gtaaacctga ggaatacctg gggcaaaagc ttgaattaga cgagcgagaa
    69781 aatacttgac atcatcatct ccaagcgctg aatagtaggt tgaattgatt tggtagatat
    69841 ctaagttgtt atactcggca ctagagtact tacgtttgac attggctcca accttataga
    69901 gttcatttga agcatagtca atctcctcat cggtcaggat atccttgaca tctactactc
    69961 caatcccatc atgggtatct agcgtcgtaa attgcttcat cgggctcatc tttaaccact
    70021 tagccaaacg ctctgttctg gaactgtaaa gagtataaag tgtcaccatt ggaagagcaa
    70081 aatcataaac atagtaatca tggtctgcta ttttaaactg aatcgaatag tgttcatgaa
    70141 tctcaggtaa aagctctgtc ccatactcag cagcgatatc tcgaactttg tccaataaat
    70201 cccaaatatc tggttccaca aagaaatcat tagtatccaa tttcttcact gcataagcaa
    70261 aggcatctag acgaatcaaa tcacacccat tacttgccaa gtgctgaatg gtcttacgga
    70321 taaattccat agttacttct ttggtcacat caagatcaat ctgctcctca ccaaaggtat
    70381 tccacaaatg ttccactgaa ccatcttcaa acacaatctc ttgctttggt gcacgatcct
    70441 tacgcttgta aattaaatct acatcagact gtgtcggacg gttttctggc caaaacttat
    70501 cccagtttaa aaagagagct ttaaattcac tggcttcatg tttttcttga tagtccttat
    70561 aatacttgga ttgacgagaa atatgattaa tcataaaatc aaacataaga taatatctct
    70621 cacctaaacg cttaacatcc tcccaatcac caaaagctga gtccacttcg tcgtagtcaa
    70681 ctggcgcaaa tccacgatca cctgttgatg ggaaaaatgg taaaaggtga actcctccaa
    70741 tagcatctcc aaaatgctct tccaaattat catataagtc tttaagatta tttccaaggc
    70801 tatcagaata ggtaatcaac atggttttat tttgaattgg catcattact ctcctttttc
    70861 taattgaagc caagtatcat atgatctggc ttcataaata aaattcattt taaatctcta
    70921 tttatcatca aactcgtact aatatagact gtgataaaca aagtactact ttcttgtttt
    70981 ctacatagaa ttatcaacaa gctgaactct tcctctgtgt caaagactat agattccatg
    71041 agctcttctt atactattcg aaaatctctt caaaccacgt cagcttcacc ttaccgtact
    71101 caagtacagc ctgcggctag cttcctagtt tgctctttga ttttcattga gtattacttc
    71161 actgccccgt tgctcattcc tgaaatgata tggcgttgga agaagagata gacaatggtg
    71221 atactgataa tgccgaccac gtaagaggca aagcttggtc cgtagtcgtt gaaatattgg
    71281 cctgcgtagt tgtattggaa caaaggcaga gtccacattt tggaatcccg gttcaagaca
    71341 aggagtggca acatgaagtc attccagaac caaagggcat tgatgatcat ggttgtcgca
    71401 tgcatcggtt tcatcattgg gaagatgatg cggaaatagg ttgtaaattg attagcccca
    71461 tcgatctctg ctgcttcatc cagactttct ggaatcgaga ttttgatata gccaacatag
    71521 agaaagaggg tctgtggaat cgcataggtc aagtagagta agatcaaacc aaaggtatta
    71581 gccaaaccga gtttactcat cataaccgta atcggaatca tgatgacttg gaaaggtacg
    71641 aagattccga ggattaagag ggtatacatg atggtaaagg cttttctttt actcatattg
    71701 cgagcgatgg agtaggctgc cataggtata aagatcatta ctgcaagtaa agataagaca
    71761 gtgatgacga cagagttcca ataatagcct ccaatcccat cagctaagag acggctaaag
    71821 ttgtcccatg tgaagttggt tggaaagcca aagaaattat ctacaatatc cttagtgggt
    71881 ttgaaggaac taaagagggt agcaaggagc ggcactaaaa tcagaaccga tcctagaatc
    71941 aatagaatgt atttgccaat cagggctttt ctttcatctt gtttcatcat gcttctcctc
    72001 ttaaatttca aatttcttag atactctcaa ttggatgatc gaaatcacta caattaagaa
    72061 gaacaagatt acggcaatgg cattggcata accgaattgg ttgtttttaa aggcatagtt
    72121 ataaaccaag agcccaagtg aggttgtggc attgtttgga ccaccaccgg tcatggcaaa
    72181 gacttggtca aaggcagtca gcccaccttt tagggctagg ataaagacta tagagacact
    72241 tggtagcaag taaggcaatt caatgttcca gaaaacttgc ttgctagtcg caccatcaat
    72301 ccttgctgcc tctgtaatct cagttggaat agattgcaaa ccagctagga agatgatgat
    72361 gggcatagcc accccttgcc aaagaaggac aaagacagcc gcaaagattg ctccccactt
    72421 agtccctaaa agactggttt ggagaaattc aatatgaagg gcattcccaa tcgctggaag
    72481 accgtagttg aagacttgct tgaagatcaa agccactgtc aaaccagata aaacagctgg
    72541 gaagaagaac caagcacgga agaaggtttg gcctttgatt ttagagttca agacacgcgc
    72601 aatgaagatc ccgagtgcaa tctcaccaac caccatgaca atcgtaatga ttgcggtaaa
    72661 gccaatcgca ttcatgaatt ttggatccat gaagaggagc ttaaagttgt ttaagccgac
    72721 aaatttgtag ttgtaagtca atcctgtcca gttggtaaaa ctgtaaaagg ctccttgaaa
    72781 catcggcaca tagaagaaaa ttgcttgtaa caagaggggg atgaccacaa aagcccatgc
    72841 ccaatatttt tgtaatactt ttttcatagt ctctctactc ctaatccaca tccgctttca
    72901 tcgggttaaa gaaggcattc aaatcattga ccatgccttg tttatcaccg gtcaagacat
    72961 agttcatggt caaggtatgg aagtctgctt cactggtcca gtattgttgc aaccagacca
    73021 agtgacgatc cgtaaaggca tattcggtca taccagcaag cggtgaatct tctcctgctt
    73081 gtttgacccc ttcgatcgct gttggagatc cgtccacatc gtagtatttt tgcatgactt
    73141 ctggacgggt catatattcc acaaaggcat tggcttcttt tggatgtttg gtggtggctg
    73201 agatagacca tgccaagtct cccgcaccaa cggttaagct ttgtcctttt tcttttcctg
    73261 gaatcatgaa ggtcccaatc ttaaagttcg gtttttgttc attaatcgct gtgatcgccc
    73321 aagacccatt tggtgtcatg aggacatccc cacgtgcgaa ggctccgata acatcggtat
    73381 agccagcacc ttcccagttc ttttgcttag agccattgat gcgaaggatg tccatgacct
    73441 tgatatcatc tttcataatc ggatccgaca atttaatggc atttggttga gaataacgaa
    73501 ggtattgatt tgcttctttt cctccacctg ttgctgtcgc aaaggctaat tgattgtaac
    73561 cattgagtgt ccaagcatct gcacctgcaa ttccaaatgg tgtttgtcct ttagcaacga
    73621 tatctttgac taactgttca aattcatccc aggtttcagg aaccttcaag cccagttctt
    73681 cgaatttatc tttgttgtag taaattccat aagcattagc tgtaaaagga acgttgtaaa
    73741 ctttttcgtt tacagcatat ttttcagcgt agccattttt cacgcgtttc aggtagtctt
    73801 tgttgctcaa atcttcaaag acacctgctt ttgcccattc ttgcagttcg atggactgtg
    73861 ggtaaatatt gaccacatca ggcacatctc ctgcgagaac gcgtgtcttc aatacttcac
    73921 cagcatttgg tacattgacg actttgacct tgatcttagg gttttccttc tcaaaatcac
    73981 gagtgatttt gagaaggttt tggtcatttc ttttttctgg ttgaaatact cgatggtcac
    74041 tgtgccatcc gcagatttac catagttgga gcaagcgccg agcccaacca aagctaaacc
    74101 tgtagttgca agaagtccga tttttttata ccattccatt agaaagcctc ctttataaat
    74161 ttatacaccc ttatcatagt cttctaaaaa tatactgtct actcaaaaaa tctccttggg
    74221 ataagataac agttaggccc gcatacatta gttctgcacc tgagtaaact tcgccatttt
    74281 cctgtaattt atatagtccc tcttcatcca aatcttttaa ttttaaagtt gtttccatgg
    74341 tctctacaac agataaaacg cgaacgtagg ttacaatcgt ttgattttcg taattaaatt
    74401 gtacagctgc ttcattggat acagtatcag gattaattag tctatactgc tgtcctaact
    74461 gaactactgg tcgtaattct ttatacaagt tcacctgatt agcaatcgta gctttctctt
    74521 catctgataa atttgtcaaa tcaagttcat agcccaaatt tcccatcatt gctacaaggc
    74581 cacgtgtttc taatggtgtc attcgtccca tctgatgatt cggtactgct gacacatgag
    74641 cccccataga aatggttgga tagagatagg atgaaccgta ttgaattggt aaacgtgcaa
    74701 tggcatcagt attatcacta gcccaaactt gtgggaaata gcgcatcata ccaagatcat
    74761 ttcgtccacc accaccagag caggactcaa agagaatatg gctgtgcttc tctgtcagat
    74821 aagaaacgag ttcgtaaagc cccagcatgt actgatgaga ttgcatctgt gtctctagat
    74881 aagttaatcc attccctagc ttagtgatat tgcggttcat atcccattta atgtaatcaa
    74941 tatcatgata agataggagt tgatctaaga cacttttcaa gtattctact acctgaggat
    75001 tggcaagatt aagtactaat tgattccgag aataagtatg ctcatagtca ggaacctgaa
    75061 tagcccagtc aggatgtcga cgatacaaat cactatctac agaaatcatt tcgggttcta
    75121 accaaagtcc aaactgcaaa cctctttcat ggatagctga aatcagactt tctagacttc
    75181 cacccagttt ttcctcatta acaacccaat cacctaaagc acgattatca tcaaaacgat
    75241 tgccaaacca accatcatct aatacaaaaa gttcaatgcc aactttctta gcttcatctg
    75301 ctaactctaa cagtttttct atctgaaagt caaagtaagt agcttcccag ttattgatta
    75361 gaattggacg ttctttttta gaaaattcac ttagcataat gtgcttcagt acaaaattct
    75421 gactttcatg actaatacca gttaatccct gatctgaatg ggtcactaaa gctaccggtg
    75481 tttcaaagta ttcctcagga gctaacttcc aagaaaagtt ttctggatta atgccaatag
    75541 ccacccgaac ttcattcaat tgattttttt gaacaaaagc ttcaaagttg ccactataca
    75601 ttagttgaat agcaaacaca ttcccagcat cctctgtgac tccttgttcg catagtagaa
    75661 gagctggtgt ttgagcatga ccagaagcac ctcggtttga gctaatcgaa aagattcctt
    75721 gttctacctg ttgacgtcta acagtctttt cacgagcata agcaccctgc agagttacta
    75781 tttcgtaatc tgcagctgga aaatcagcca taaaagaaaa atctttatgg atgacaactt
    75841 cctgattact attattatct aatttactgt agctagcaat agtcgcatca ttattaaaag
    75901 tagtataata caaagtcaga ctaagttgag ccttagaatc ttctaacatt aagacaagag
    75961 tctctgtatc gtccatgcta tgtggagaag gtaagccctg tggaccattc tgacctttta
    76021 aaatctttgc ttctacaaat cgaaagtctg ttacttcagt tacactatgc tgaacctgta
    76081 tggttggttt cctaaaatct cctaagccat gttgtccaaa aatctgtcgc tgagtatcta
    76141 aactaaaggt tcgattagta gccgttggat ttcctgaaaa ggcatggtct cgttcataaa
    76201 cactattgga acctttatag ttcttaatag tctttcctaa atgtttcaaa agtaagtagc
    76261 catttcgatt ttcaataatc aaacttagat ttttactctc aacataaaat agattattct
    76321 ctatcctaac tcccatttac ttcacctcat cactttattg attatatttt atcacctgaa
    76381 atcgctttcc aaaatagaaa aatgtctcaa gaatatggta aaatgttagg taggaggtag
    76441 cacatgttag ttttttcaga ataccagact ggaacaatcg accttgccct aagcttttat
    76501 ggatatgagg aatgcacacc taattactct tttggtccag ccattcgtga tacatacgtt
    76561 ctacattaca ttactaaagg acaaggaaaa ttttattaca agggtaaaat tgttgattta
    76621 aaagaaggag atttctttct attaaaacca gaggaactaa ccttttatca agcagatagt
    76681 aaagaacctt gggcctacta ctggttagga atcactggag ggaaatcccc tgattatttt
    76741 gctctttccc aaatttctga tcaatcctat ctcatccaat ctgaaacttg tcatacccag
    76801 actactgcaa aactcatctc agacattgtc cgcttcgctc agattacaaa atcaagtgaa
    76861 ttagctcaac tccatatcat gggacaactt catgaactga tgtttcatat gggaactatt
    76921 gctcccaatc agaaaaaaaa gaatatttca tcaacccacc aactctatct tgaatgcaaa
    76981 cgattaattg atagccacta tcctcaatca cttacaattc aagatttagc aaaagaacta
    77041 tccgttcaca gaagctactt atcaagcgta ttcaaagaat ttaatacctt atcacccaaa
    77101 gaatacctac tctacgttcg aatgcaccga gctagacaac ttctcgaaaa tacccaagag
    77161 tccatcaagg taattgcata ctcggtaggt ttttcagatc cactccattt ttcgaaagct
    77221 tataaacaat actttaatca gactccaagt catacaagaa aagaatactc tcaataccaa
    77281 ctagtgagaa aggcaacatt atgaaatcct accaagctgt ctaccaaatc ctatctaaag
    77341 aaaccgacta tatcagcgga gaaaaaatcg cagaaaaact atccctaagc cgaacatcaa
    77401 tttggaaagc catcaagcga ctagaacaag aaggcattga aattgatagt atcaaaaata
    77461 gaggatataa attgatgaat ggtgacctta ttcttccaga gattctagaa gaaaatcttc
    77521 caattaaagt cagctttaaa cccgaaacaa aatcaacaca actagatgca aaagaagcaa
    77581 ttgatttagg ccatgaagca aataccctct atctagcttc ctatcaaaca gcaggccgag
    77641 gccgttttca acgttccttc tactcaccac aaggtggtat ttatatgaca ctccatctta
    77701 aaccaaatct cccctatgac aaattaccat cctacacact acttgtagct ggagctgtct
    77761 acaaagctat taagaaccta actttaatag atgtcgacat aaaatgggtc aatgatatct
    77821 atctaaacaa tcataaaatt ggaggaatcc ttactgaagc aatgacctct gtagaaactg
    77881 gcttagtcac agatatcatt attggagtag gtatcaattt cactattaaa gacttccctc
    77941 aggaattaaa agaaaaagct gccagcttat ttaaagctac agctcctata acaaggaatg
    78001 aattgatcat agaaatctgg cgtgctttct tcgaaacacc agcagaagag ctattatacc
    78061 tatacaaaaa acagtcattc attctaggaa aagaagtcac tttcacacta gagcaaaaag
    78121 actacaaggg acttgctaaa gacatctcag aaaatggaaa acttttaatt caatgtgata
    78181 acggaaaaga aatctggcta aatagtggcg aaatttctct caatagttgg aagtaaaata
    78241 acacaattat aatataaacg atataaaaat aacttcagat tagtaattca attaagtttt
    78301 acggatctga agttttattg tctctaaaaa caaaaaagag agttacaaac tctcattaaa
    78361 acggagaata agggattcga acccttgcgc cagttacccg acctaacgat ttagcaaacc
    78421 gtcctcttca gcctcttgag taattctcca attaatgggc acgagtggac tcgaaccacc
    78481 gacctcacgc ttatcaggcg tgcgctctaa ccacctgagc tacgcgccca agttaaaaaa
    78541 cttggtaatt tgaacaaagt tcaaagcggg tgacgagaat cgaactcgcg acaacagctt
    78601 ggaaggctgt agttttacca ctaaactaca cccgcataaa tactatcaat
//
LOCUS       DBERDS010000005        73647 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.005, whole genome shotgun sequence.
ACCESSION   DBERDS010000005 DBERDS010000000
VERSION     DBERDS010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 73647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.005"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..183
                     /locus_tag="ACL73E_000368"
     CDS             <1..183
                     /locus_tag="ACL73E_000368"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800405.1"
                     /translation="TGLPLKKWTFSRAFCRALKSSPNHQIEIRNSLDKTIDFSYSLSF
                     FYLPLYHTFSVYGSSL"
     gene            complement(180..2069)
                     /locus_tag="ACL73E_000369"
     CDS             complement(180..2069)
                     /locus_tag="ACL73E_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGS0800406.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2207..3772
                     /locus_tag="ACL73E_000370"
     CDS             2207..3772
                     /locus_tag="ACL73E_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS0800407.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3772..4536
                     /locus_tag="ACL73E_000371"
     CDS             3772..4536
                     /locus_tag="ACL73E_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0800408.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4735..4950)
                     /locus_tag="ACL73E_000372"
     CDS             complement(4735..4950)
                     /locus_tag="ACL73E_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800409.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(5821..7071)
                     /gene="ilvA"
                     /locus_tag="ACL73E_000373"
     CDS             complement(5821..7071)
                     /gene="ilvA"
                     /locus_tag="ACL73E_000373"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGS0800410.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7121..7477)
                     /locus_tag="ACL73E_000374"
     CDS             complement(7121..7477)
                     /locus_tag="ACL73E_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS0800411.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7715..7951)
                     /locus_tag="ACL73E_000375"
     CDS             complement(7715..7951)
                     /locus_tag="ACL73E_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800412.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(8058..9080)
                     /gene="ilvC"
                     /locus_tag="ACL73E_000376"
     CDS             complement(8058..9080)
                     /gene="ilvC"
                     /locus_tag="ACL73E_000376"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGS0800413.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9146..9622)
                     /gene="ilvN"
                     /locus_tag="ACL73E_000377"
     CDS             complement(9146..9622)
                     /gene="ilvN"
                     /locus_tag="ACL73E_000377"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGS0800414.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9615..11315)
                     /locus_tag="ACL73E_000378"
     CDS             complement(9615..11315)
                     /locus_tag="ACL73E_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGS0800415.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11516..13183)
                     /locus_tag="ACL73E_000379"
     CDS             complement(11516..13183)
                     /locus_tag="ACL73E_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGS0800416.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13186..13551)
                     /locus_tag="ACL73E_000380"
     CDS             complement(13186..13551)
                     /locus_tag="ACL73E_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0800417.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13708..13896)
                     /gene="rpmB"
                     /locus_tag="ACL73E_000381"
     CDS             complement(13708..13896)
                     /gene="rpmB"
                     /locus_tag="ACL73E_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGS0800418.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14012..14188)
                     /locus_tag="ACL73E_000382"
     CDS             complement(14012..14188)
                     /locus_tag="ACL73E_000382"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0800419.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14299..14496)
                     /locus_tag="ACL73E_000383"
     CDS             complement(14299..14496)
                     /locus_tag="ACL73E_000383"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800420.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(14924..16468)
                     /locus_tag="ACL73E_000384"
     CDS             complement(14924..16468)
                     /locus_tag="ACL73E_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGS0800421.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16681..16983
                     /gene="gatC"
                     /locus_tag="ACL73E_000385"
     CDS             16681..16983
                     /gene="gatC"
                     /locus_tag="ACL73E_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGS0800422.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA"
     gene            16983..18449
                     /gene="gatA"
                     /locus_tag="ACL73E_000386"
     CDS             16983..18449
                     /gene="gatA"
                     /locus_tag="ACL73E_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGS0800423.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAHVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TIQSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18449..19891
                     /gene="gatB"
                     /locus_tag="ACL73E_000387"
     CDS             18449..19891
                     /gene="gatB"
                     /locus_tag="ACL73E_000387"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGS0800424.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEIAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20020..20580
                     /gene="efp"
                     /locus_tag="ACL73E_000388"
     CDS             20020..20580
                     /gene="efp"
                     /locus_tag="ACL73E_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGS0800425.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20602..20991
                     /locus_tag="ACL73E_000389"
     CDS             20602..20991
                     /locus_tag="ACL73E_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0800426.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20984..21406
                     /gene="nusB"
                     /locus_tag="ACL73E_000390"
     CDS             20984..21406
                     /gene="nusB"
                     /locus_tag="ACL73E_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGS0800427.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21456..21692)
                     /locus_tag="ACL73E_000391"
     CDS             complement(21456..21692)
                     /locus_tag="ACL73E_000391"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGS0800428.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21705..22179)
                     /locus_tag="ACL73E_000392"
                     /pseudo
     CDS             complement(21705..22179)
                     /locus_tag="ACL73E_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22197..22382)
                     /gene="briC"
                     /locus_tag="ACL73E_000393"
     CDS             complement(22197..22382)
                     /gene="briC"
                     /locus_tag="ACL73E_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGS0800429.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22541..23308)
                     /locus_tag="ACL73E_000394"
     CDS             complement(22541..23308)
                     /locus_tag="ACL73E_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGS0800430.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARFSQKPLEELLEERYQRFRKY"
     gene            complement(23305..24171)
                     /gene="accD"
                     /locus_tag="ACL73E_000395"
     CDS             complement(23305..24171)
                     /gene="accD"
                     /locus_tag="ACL73E_000395"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGS0800431.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24208..25575)
                     /gene="accC"
                     /locus_tag="ACL73E_000396"
     CDS             complement(24208..25575)
                     /gene="accC"
                     /locus_tag="ACL73E_000396"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGS0800432.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25587..26009)
                     /gene="fabZ"
                     /locus_tag="ACL73E_000397"
     CDS             complement(25587..26009)
                     /gene="fabZ"
                     /locus_tag="ACL73E_000397"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGS0800433.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(26006..26491)
                     /gene="accB"
                     /locus_tag="ACL73E_000398"
     CDS             complement(26006..26491)
                     /gene="accB"
                     /locus_tag="ACL73E_000398"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGS0800434.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26494..27729)
                     /gene="fabF"
                     /locus_tag="ACL73E_000399"
     CDS             complement(26494..27729)
                     /gene="fabF"
                     /locus_tag="ACL73E_000399"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGS0800435.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27751..28482)
                     /gene="fabG"
                     /locus_tag="ACL73E_000400"
     CDS             complement(27751..28482)
                     /gene="fabG"
                     /locus_tag="ACL73E_000400"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGS0800436.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(28516..29436)
                     /gene="fabD"
                     /locus_tag="ACL73E_000401"
     CDS             complement(28516..29436)
                     /gene="fabD"
                     /locus_tag="ACL73E_000401"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGS0800437.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29429..30403)
                     /gene="fabK"
                     /locus_tag="ACL73E_000402"
     CDS             complement(29429..30403)
                     /gene="fabK"
                     /locus_tag="ACL73E_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGS0800438.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30522..30746)
                     /locus_tag="ACL73E_000403"
     CDS             complement(30522..30746)
                     /locus_tag="ACL73E_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS0800439.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30806..31780)
                     /locus_tag="ACL73E_000404"
     CDS             complement(30806..31780)
                     /locus_tag="ACL73E_000404"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGS0800440.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31780..32214)
                     /locus_tag="ACL73E_000405"
     CDS             complement(31780..32214)
                     /locus_tag="ACL73E_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS0800441.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32308..33093)
                     /locus_tag="ACL73E_000406"
     CDS             complement(32308..33093)
                     /locus_tag="ACL73E_000406"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGS0800442.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33418..34782
                     /locus_tag="ACL73E_000407"
     CDS             33418..34782
                     /locus_tag="ACL73E_000407"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGS0800443.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34785..35156
                     /locus_tag="ACL73E_000408"
     CDS             34785..35156
                     /locus_tag="ACL73E_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGS0800444.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35370..36644
                     /gene="serS"
                     /locus_tag="ACL73E_000409"
     CDS             35370..36644
                     /gene="serS"
                     /locus_tag="ACL73E_000409"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGS0800445.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDTKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36669..37568)
                     /locus_tag="ACL73E_000410"
     CDS             complement(36669..37568)
                     /locus_tag="ACL73E_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGS0800446.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37678..38226)
                     /locus_tag="ACL73E_000411"
     CDS             complement(37678..38226)
                     /locus_tag="ACL73E_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGS0800447.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38444..39766)
                     /locus_tag="ACL73E_000412"
     CDS             complement(38444..39766)
                     /locus_tag="ACL73E_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGS0800448.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39857..39945)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40110..42446)
                     /locus_tag="ACL73E_000413"
     CDS             complement(40110..42446)
                     /locus_tag="ACL73E_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGS0800449.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEKLARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDIFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42550..43098)
                     /locus_tag="ACL73E_000414"
     CDS             complement(42550..43098)
                     /locus_tag="ACL73E_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGS0800450.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43095..43397)
                     /gene="zapA"
                     /locus_tag="ACL73E_000415"
     CDS             complement(43095..43397)
                     /gene="zapA"
                     /locus_tag="ACL73E_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGS0800451.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43484..44365
                     /gene="rnhC"
                     /locus_tag="ACL73E_000416"
     CDS             43484..44365
                     /gene="rnhC"
                     /locus_tag="ACL73E_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGS0800452.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEKKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44369..44983
                     /gene="lepB"
                     /locus_tag="ACL73E_000417"
     CDS             44369..44983
                     /gene="lepB"
                     /locus_tag="ACL73E_000417"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGS0800453.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45262..47628
                     /locus_tag="ACL73E_000418"
     CDS             45262..47628
                     /locus_tag="ACL73E_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGS0800454.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47676..48959)
                     /gene="tig"
                     /locus_tag="ACL73E_000419"
     CDS             complement(47676..48959)
                     /gene="tig"
                     /locus_tag="ACL73E_000419"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGS0800455.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49153..49512)
                     /locus_tag="ACL73E_000420"
     CDS             complement(49153..49512)
                     /locus_tag="ACL73E_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0800456.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(49814..50404)
                     /gene="cbpG"
                     /locus_tag="ACL73E_000421"
                     /pseudo
     CDS             complement(49814..50404)
                     /gene="cbpG"
                     /locus_tag="ACL73E_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(50485..50724)
                     /locus_tag="ACL73E_000422"
     CDS             complement(50485..50724)
                     /locus_tag="ACL73E_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800457.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(50874..51416)
                     /locus_tag="ACL73E_000423"
                     /pseudo
     CDS             complement(50874..51416)
                     /locus_tag="ACL73E_000423"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51398..51640)
                     /locus_tag="ACL73E_000424"
     CDS             complement(51398..51640)
                     /locus_tag="ACL73E_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HGS0800458.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(51641..52273)
                     /locus_tag="ACL73E_000425"
     CDS             complement(51641..52273)
                     /locus_tag="ACL73E_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0800459.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFIFLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(52287..53282)
                     /locus_tag="ACL73E_000426"
     CDS             complement(52287..53282)
                     /locus_tag="ACL73E_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0800460.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(53279..53977)
                     /gene="liaF"
                     /locus_tag="ACL73E_000427"
     CDS             complement(53279..53977)
                     /gene="liaF"
                     /locus_tag="ACL73E_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGS0800461.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKNYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(54055..55065)
                     /gene="fni"
                     /locus_tag="ACL73E_000428"
     CDS             complement(54055..55065)
                     /gene="fni"
                     /locus_tag="ACL73E_000428"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGS0800462.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLHTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVLGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(55049..56056)
                     /locus_tag="ACL73E_000429"
     CDS             complement(55049..56056)
                     /locus_tag="ACL73E_000429"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGS0800463.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(56043..56996)
                     /gene="mvaD"
                     /locus_tag="ACL73E_000430"
     CDS             complement(56043..56996)
                     /gene="mvaD"
                     /locus_tag="ACL73E_000430"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGS0800464.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(56978..57856)
                     /gene="mvk"
                     /locus_tag="ACL73E_000431"
     CDS             complement(56978..57856)
                     /gene="mvk"
                     /locus_tag="ACL73E_000431"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGS0800465.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(57978..58994)
                     /gene="cbpC"
                     /locus_tag="ACL73E_000432"
     CDS             complement(57978..58994)
                     /gene="cbpC"
                     /locus_tag="ACL73E_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGS0800466.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            complement(59092..59781)
                     /locus_tag="ACL73E_000433"
     CDS             complement(59092..59781)
                     /locus_tag="ACL73E_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0800467.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(59793..61217)
                     /gene="gndA"
                     /locus_tag="ACL73E_000434"
     CDS             complement(59793..61217)
                     /gene="gndA"
                     /locus_tag="ACL73E_000434"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGS0800468.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(61293..62687)
                     /gene="mapZ"
                     /locus_tag="ACL73E_000435"
     CDS             complement(61293..62687)
                     /gene="mapZ"
                     /locus_tag="ACL73E_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGS0800469.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(62699..63856)
                     /locus_tag="ACL73E_000436"
     CDS             complement(62699..63856)
                     /locus_tag="ACL73E_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGS0800470.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(63941..64321)
                     /gene="rnpB"
                     /locus_tag="ACL73E_000437"
     ncRNA           complement(63941..64321)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL73E_000437"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(64342..64671)
                     /gene="gpsB"
                     /locus_tag="ACL73E_000438"
     CDS             complement(64342..64671)
                     /gene="gpsB"
                     /locus_tag="ACL73E_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGS0800471.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(64741..65268)
                     /locus_tag="ACL73E_000439"
     CDS             complement(64741..65268)
                     /locus_tag="ACL73E_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGS0800472.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            65334..65930
                     /gene="recU"
                     /locus_tag="ACL73E_000440"
     CDS             65334..65930
                     /gene="recU"
                     /locus_tag="ACL73E_000440"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGS0800473.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            65927..68086
                     /gene="pbp1a"
                     /locus_tag="ACL73E_000441"
     CDS             65927..68086
                     /gene="pbp1a"
                     /locus_tag="ACL73E_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGS0800474.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAA
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(68253..73556)
                     /locus_tag="ACL73E_000442"
     CDS             complement(68253..73556)
                     /locus_tag="ACL73E_000442"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGS0800475.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTASTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSIKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HSRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKLVVTRKSNDVNSPLYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYSFVVGKGEFQSGRRGTQASNLEIHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FESLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
BASE COUNT        21424 a        16915 c        13672 g        21636 t
ORIGIN      
        1 acaggattac ctttgaaaaa atggactttt tcaagggctt tttgccgtgc tctaaaatca
       61 tcgccaaatc atcaaattga aataagaaat agtttagata aaactattga cttttcttat
      121 agtttgtctt ttttctatct tccattatat catacttttt cagtctatgg tagctctctt
      181 taaaaggcac cgatactgcc gccacctccg cctccagaga agccaccacc agaacttcca
      241 cttccagaag atacagagta ggtgcttgct gtatttgcga cactagcata atggctcatt
      301 tgcgcgcttg aatgataaaa cagactgtgc cagccataag ctacatagag attgatatct
      361 ggattttcca cttgaatctg atgaaccttc atcaaatgac taaccttgtc cgcatagcca
      421 aataaggtcg catagaccaa gaggcgattc cagaccacaa tactttccag ttcagcctga
      481 tccaatcgtg caatctcacg caacatattt tcaaaactgg tccagagata gtagacctca
      541 gctcccgctt catttagaac accatcacga ttatctagtc gaagcttcca ataatagaaa
      601 acagacaaaa ctaaccctag aaaaccaagt attggcaaag ggaggtaaag atagccatga
      661 acgtctaaac tgtacaagaa caaaccaaat ccgataaata ggggcaggat agtcaaggca
      721 cccataccca cttgcaaggc cttttcccca ccagttaaag gacgataata atctgggagc
      781 ccccagaagg aaactcgttt tctcactcct tcttgcatct ggttcaatac ctcttcaaaa
      841 gaagatttga gttgaagccc tcttgcttga atccgttttt catcagaaac tttggctcta
      901 cgataaagac tatcagatac cttgtaatcc gcaaacaaat tggaaagagt ttcttctttt
      961 ttacctgaaa aagctagatt taggcagtct ttctcaaagc ttgacaaacc atcttctttt
     1021 actagcctca aaccaactgc atctccttct gaaatgatag agacattccc acggtctatc
     1081 acatctagca aggtagcttg aataagttga tcaaaggtga attttccagc tcccttgacc
     1141 aagggactca cttcctccaa ggaggtcgag tagactgctt ctgataaaac cataggctct
     1201 aattccattg gtggttcata gagacgatga tttttggcat atttgactga aggagtggtc
     1261 tttcttctat aaataaaata gaagcagaca ctcaataaca aggagataga aaggatcgaa
     1321 gggaggaccc aagtaacaag ttgtttactc tgatcttttt ctctaacaat cgagtcttct
     1381 atcttattaa actcttctaa acgattccct ttcaatccct gatccctagc gctagcaaaa
     1441 tcggtccgag gccaataggc atgcaactca actccacgct tagccggaag attgtctaaa
     1501 cggatagtat aatcaaggtt actcttttca atcgttccct ctctaaaaag tttccctgta
     1561 tggaaaaaga gtttttcagc tcccttgtct ccccttacat gaaattcaaa cttttcaata
     1621 gactctgaac tatctgtcag aggttgccaa tttaattcag cgatatcatc ataaaggaaa
     1681 agtaaatttt ttaagttcca gacgaggtca acttcaacta tgtcgccctc ctgacctgga
     1741 ttatagactc tcacagtata accatccgct tcttctgtta cttcgctagt cacatctgct
     1801 agttctgcac cgtttttcgc ggcctgaacc tttggatgag ggtcaatgtc aaacccgcta
     1861 ggcatcttac cagcacgtcc aagtcccacg atttgtccct taaagtcctc ctcaaactgg
     1921 taaactatct tctgtctaaa ctctgccgta ttatctgcat gaatatacaa atccccttga
     1981 taagagttta tcttgaaatc aatggcaaaa acagagagtg gaagaaggca aaacaagcct
     2041 aacaccagta agaaaaaagt ttttttcatc aactaagccc cctttttatc tttcttatca
     2101 ttatagcatt ttttcgtaag taaaggctta cttatgttga aaaattacgc atttttcgat
     2161 aaaataggag acagttattt tttaatagat cagaatagga gaaatcatga gaaaaatata
     2221 cttatctatt ttcacaagtc tcttgctgat gctaggactt gtcaatgttg ctcaagccga
     2281 tgaatattta cgcatcggga tggaagcagc atatgctccc tttaactgga cccaggatga
     2341 tgatagcaac ggagctgtca aaatcgatgg gaccaatcag tatgccaacg gatacgatgt
     2401 tcaaatcgcc aagaaaatcg ctaaggactt aggtaaaaaa cctttggttg ttaaaaccaa
     2461 gtgggaaggt ctagtccctg cccttacttc tggtaagatt gacatgatta tcgcaggtat
     2521 gagtccaact gcagaacgca aacaagaaat tgccttttcg agcagttact acactagcga
     2581 accagttttg cttgtcaaaa aagattctgc ctacgcaagt gctaaatctt tggatgactt
     2641 taacggtgca aaaatcactt ctcaacaagg ggtctacctc tacgacttga ttgcacaaat
     2701 cccaggtgct aaaaaagaaa cagccatggg agacttcgct caaatgcgac aagctcttga
     2761 ggctggtgtc attgatgctt atgtttctga acgtccagaa gcactgactg ctgaagctgc
     2821 gaactctaag ttcaagatga ttcaagtaga acctggtttc aaaactgggg aagaagatac
     2881 agctatcgct atcgggcttc gtaaaaatga caatcgtatt agccaaatca atgccagcat
     2941 tgaaaccatt tcaaaagatg accaagttgc cttgatggat cgtatgatca aggaacaacc
     3001 tgccgaagct acaacaactg aagagactag cagtagtttc tttagccaag tcgctaaaat
     3061 tctttctgaa aactggcaac aactcttgcg tggtgctggt atcactcttt taatctctat
     3121 cgtcggaacc atcataggtc tcattattgg acttgccatt ggtgtcttcc gtactgctcc
     3181 tctctctgaa aacaaagcca tttatggcct tcaaaaacta gtcggctggg ttctcaatgt
     3241 ctacattgaa attttccgtg gtacgccaat gattgttcaa tcgatggtta tctactatgg
     3301 aactgcccaa gctttcggta tcaaccttga ccgtacacta gctgctatct tcatcgtttc
     3361 aatcaatacc ggtgcctaca tgactgaaat tgtccgtggt ggtatcctgg cagttgacaa
     3421 gggacaattt gaagctgcga ctgctcttgg tatgactcat aaccaaacca tgtgtaagat
     3481 tgtcctacct caggttgtcc gcaatatcct accagcaact ggtaatgaat ttgtcatcaa
     3541 tatcaaagat acatctgtat tgaacgttat ctctgttgtc gaactttatt tctcaggaaa
     3601 taccgtggca acacaaacct atcaatactt ccagacattt acaatcatcg ccgtgattta
     3661 ctttgtcctc accttcaccg taacacgtat cctacgcttt atcgagcgca gaatggacat
     3721 ggatacctac actacaggtg ctaaccaaat gcaaacggag gatttgaaat aatgacacaa
     3781 gcaatccttg aaattaaaca cctcaaaaaa tcctatggac aaaacgaagt gctaaaagac
     3841 atttctctca ctgtccacaa gggagaagtt atttctatca tcggaagctc tggaagtggg
     3901 aaatcaacct tcctacgctc cattaaccta cttgaaacgc caactgatgg acaaatcctt
     3961 tatcatggac aaaacgtcct cgaaaaaggc tatgacctca cgcaataccg tgaaaagtta
     4021 gggatggttt tccaatcctt taacctcttt gaaaatctca acgttcttga aaacacaatc
     4081 gtcgctcaga caactgtcct taaacgcgaa cgcacagaag ctgaagaaat tgccaaagaa
     4141 aacctggaaa aggtcggcat gggagaacgc tactggcaag cgagacccaa acaactctca
     4201 ggtggtcaaa aacaacgtgt ggccatcgct cgtgcccttt caatgaatcc tgacgccatt
     4261 ctctttgatg aaccaacatc agctctcgat ccagaaatgg ttggagaggt cctcaaaatc
     4321 atgcaagatc tggctcagga aggcttgacc atgattgtcg taacccatga aatggaattt
     4381 gcccgtgatg tctctcaccg tgttatcttt atggataagg gtgtgattgc tgaagaaggt
     4441 aaaccagaag acctcttcac taatcctaaa gaagaccgta caaaagaatt tcttcaacgt
     4501 tatctcatac tcaatgaaaa tcaaagagca aactaggcag ctagccgcag gttgctcaaa
     4561 acactgtttt gaggttgcag atagagctga cgtggtttga agagattttc gaagagtatc
     4621 aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag
     4681 gcagattctc tatctctact acttgaaggt caagaatcca ccgttatcca aagattaatc
     4741 ttcaaatttt tcatgatttt tttcatagaa atcaattaag cctagggctg tttcaaatga
     4801 aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt
     4861 cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga
     4921 ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat
     4981 ttaattgtat acgtttttac tacttttgtc aaaaaaaaaa acatatattc aacgaaaata
     5041 attagttcag aattttctta cttccttttt aaatccgata atatataggt tttgctagcc
     5101 tctacaccat aaatatttgc taataaaaat actgtattat taccctctta aggtgcaaaa
     5161 ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag atagcttatt tcttcgattt
     5221 aagaactgaa gatgatagtt ctaaccttta gaaatccaag ccttctctag ctcaaaaact
     5281 cctatctttc ttcctcaata aatcatctga gagataggta ttccttatat ccttcaaatt
     5341 catcactcct ttggatattg aggtgctagc ctagaagcag acacccgatt atctaaacca
     5401 tccttaatag agatgacaag acagataagc tcagttaatt acttatatat ctttttaata
     5461 tggtatattt gtcaacaaaa agaaatcaaa tcatacctta tactcaatga aaatcaaaga
     5521 gcaaactagg aagctagccg caaattgctc aaaacactgt tttgaggttt cagatagagc
     5581 taacgtggtt tgaagagatt ttcgaagagt attaaagaca gtatgactat gcttgtcaat
     5641 agataggaaa tcaaaatgaa ggatggaaat ctgagccaaa catcataagt gctataatga
     5701 acagaagtaa gaattgcacg ataagttttc taaaaccata ggaatcgtcc cctttcttca
     5761 tcttcattat agcacatata catcagttgt acaaataata tgatattttt ttattagtcc
     5821 tcagacaagc atattataaa gcgtttcatt accatttaag ttaatataag ctggatcaaa
     5881 accttccatt ctacggatca aacctgcata atcatgctta tctgccaaag cgatcccaat
     5941 caatactggg cctgttccct tgctagctcg tttgatatac tcaaaacgtg tgatatcatc
     6001 atttggcccc aggatatcat ttacaaactc acgcaaagct cctggacgct gtgggaaatt
     6061 gaccacaaag taatgtttga taccatcata aatcaaggca cgctcttcca tttctggcat
     6121 acggttgata tcattatttc ctccagaaat gatacaacaa atggttttcc ccttaatata
     6181 ttcagctaaa acctctaaag aggcgatact agccgctcca gcaggttctg cgactatccc
     6241 ttgcttagag taaaggtcaa tcaaggtttc agaaatcaat ccctcatcga cacctaccaa
     6301 agtttgaata tgttgacgag ttgcttcata ggtcaactga cctacctttt gcacagcaat
     6361 cccatccgca aatttatcaa tttccttgag tttgactgga cctccagcct caaaggcagc
     6421 tttcatggaa cgcgctccat tcgcctctac tccgataacc tcaatctctg gacttgtttc
     6481 cttgatatag gtagaaaccc cggcaatgag accgccacca ccaacaggaa ccaagacagc
     6541 atcaaaatca atcgattctt ttcgagcttc ttctaaaatc tcataagcaa ctgttccttg
     6601 acctgcttga acatgagcat catcaaaagg atcaataaag gtacgatttt cagagactgt
     6661 aaattcttga gctgctttgg ctgaggcatc aaaggtatct ccaactagtt taatagttac
     6721 aaaatcccca ccaaaaaagc gaacctgacc aatcttttgt tgtggcgtag taataggcat
     6781 aaagatagta gcaggaattt tcatttcatt acaagtatag gctactccct gcgcatgatt
     6841 tcccgcagaa gcgcagacta ccccacgttc acgttcttcc ttgctgagct gggaaatggc
     6901 ataataggca ccacgaattt taaaggagcg aacacgctgg gcattttctt ttttcaaata
     6961 aatcttagca ccatacttct ccgataaata atgatcgtaa tccagtggag tattcacaac
     7021 cacaccgttc aagaccttgt gagccttgat tatatctttt gaacttaaca tataaaacct
     7081 ctttttctat aaaaaacagt cactaatgac tgttttttag ttattcatct ccgaaaactt
     7141 cagtaacact ttcatggtat ttatgagcca tacgaatcga aaactcttta ggaagttcat
     7201 aacgatttgt ggaaatccaa tcatataacc attctaccaa actttcttca ctatcattac
     7261 gatggaagat aaaatagttt aaaatttctt tatattctac atcattcaaa tccaacgtgt
     7321 ctacaaattg actacgagga acaaaattag aatctaattt tcttagttga tctgtcaatt
     7381 ctcccaattg taaatccaac tgaaaaaata gtttttgcag ttgcctatca gtttcatcac
     7441 atcctgtctt gatagaaaac aaattggtaa tattcatatg atttcaaccc ctaaataagt
     7501 acatctaata tcccacgaat agctgaagct aaagttttcg cagtccagtc atttaaaccc
     7561 gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc atctatcgtc
     7621 tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa tctaacagct
     7681 gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt ctcaaaatcc
     7741 atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga gaatgaattt
     7801 caagaccttc ttctctagct atttgtgcca atttgaagaa ttgttcaaag gtcatatgca
     7861 acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt tcatcatacg
     7921 accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt acattataca
     7981 actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa atcatctcca
     8041 gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt tttaccaaca
     8101 aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt agctgcttgt
     8161 tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa gtcatttgca
     8221 aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac ttgttcagtg
     8281 attacacgtg gacctgatac atagtcaccg tattcagcag tgtttgaaat agattgacgc
     8341 attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc gtgaagaact
     8401 tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa acctgcttcg
     8461 ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc ttcttcagtt
     8521 tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc tttacaccag
     8581 tccatagcaa tgtttttagc atttcctgtt gcatcttggt atactgcata aagagctgga
     8641 acaccaaatc cttcttcgta agtacgacgt accaagtgtc ccggtccttt aggagcacac
     8701 atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt gaaaccatgg
     8761 gcaaatccaa ctgcgtttcc agcttccaag tttggagcga tttctgcttc gtacaattct
     8821 tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt agcttctact
     8881 actgtgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc tggacgtaca
     8941 ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg tccttgtgaa
     9001 ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac atctttttca
     9061 tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc cttttaggct
     9121 ggtttaataa atttaagttg gatttttaat cgcgggtaaa tccagttgca cccgttcgag
     9181 caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc ttttctgcat
     9241 ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt gcacggaaag
     9301 gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc ttaaccaaaa
     9361 tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc acatcaatct
     9421 gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca tcaataataa
     9481 tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt tcaatattaa
     9541 cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga ttttgtagtt
     9601 ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt actcttacca
     9661 gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat tagcatagga
     9721 acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc aaacttatag
     9781 tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc aaagaccgac
     9841 tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc aagtgaatga
     9901 ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc caactcctgg
     9961 ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc tgggttagca
    10021 attttagcac cgattgctgc tggaattcca aagcccattg ttcccaaacc acctgaagtc
    10081 actaactgac gctcattttg gtagggataa tactgagctg tccacatttg gtgttgacca
    10141 acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc aataactgct
    10201 tgcggttgaa ccacacgctc tttcttgtca taagaacgaa cacgattctt gtctttagtg
    10261 actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag caacatttgc
    10321 aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt gccaatctca
    10381 gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt aggattcccc
    10441 gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc cgtcatggca
    10501 atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg gtgactcgtt
    10561 gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg ttctgcaaat
    10621 tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa caagactggc
    10681 tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt cggctcaaga
    10741 gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt ttctaaagca
    10801 gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt tgcgatatgg
    10861 acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta attgtactta
    10921 gtgattggca tggtaattcc tacgatgtct gcctcctgaa aggcatcctt cccaatccct
    10981 gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat agcatccgca
    11041 atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac acccaacttt
    11101 ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg gcgccctaga
    11161 atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac cgcaccacca
    11221 ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac taggtccgac
    11281 cccgtcttag gagattctaa actgattttc tccattgttc ccctttcttt cctcttaaaa
    11341 ataacttgtt actatcatac cattttttca aaatttttca agataaaaga agaaattttc
    11401 tgaattttct attttaacgt ttatttatga atgttatttt tgtttttatt aaaaagatac
    11461 cgatttcatt tactaaaaaa gaaaaaagaa ctgatttctc agtccttcat taatcttatt
    11521 ccacactaaa taggtatggg taaacaggtt gttgaccttg gtgaatctcg acttcaacgt
    11581 cttcgaattc ttctacgatt tcttgagcga tttcattggc aagttcttcg cttccgtctt
    11641 caccgacata gaaggttacg atttcactat cttcatccaa catatgtttc aaggtttcag
    11701 tcaatgtttg gtgcatatca gggtttgaca caagaatttt tccatccacc atacctagat
    11761 tatcgttttc atggatttct aagccatcga tcgttgtatc acgcacggct gttgtgacgc
    11821 ttccgctaac gacatcgcta agagcagctg tcatacgctc ttggttttct tcaatggact
    11881 tgcttggatc aaaggcaaga agacttgtca taccttgagg aagagtgcga gcctctacca
    11941 ctactgctgg ttgctccaaa acttctgccg cagattgagc tgccatgaag atgttcttgt
    12001 tgtttggcaa gaagatgatg ttacgggcat tgacctgttc aacagccttg ataaagtctt
    12061 ctgttgaagg gttcatggtt tgaccgcctt cgataacata atccacgcct tgagaacaga
    12121 agatatctgc tagaccttta ccagccacca cagcaatcaa agcatactct ttttcttcag
    12181 ccgacttgat aacttgagta gcttctttct caacctgtgc ttcgtgttgg ttacgcatat
    12241 tgtcaacttt taccttgacc aagctaccat atttgagacc ttcttgcata acaagtcctg
    12301 gatcttctgt atgaacatgg actttgacaa tttcatcatc gttaacaacg aggagagaat
    12361 ccccaagctc atccaagtag ttacggaatt catcgtagtc aaaatcttta gcataggttg
    12421 gaccttgctt aagagctacc atgatttcag tacagtaacc aaacgtgatg tcctcagtcg
    12481 ctacgtgacc agctacagac ttatgatgct ctacattgat catctcactc atgttggcag
    12541 gagtcgctac aaagtcctca gatgcaatat attcgccagt aagggctgaa aggaaacctt
    12601 cgtagatgaa gaccaatcct tgaccacctg agtccacaac gccaacttct ttcaatactg
    12661 gaagcatgtc tggtgtttta gctagagctg ttttagcacc ttccaaggct gcgcgcatga
    12721 cttcaacagt gtcatctgtt tgctcagctt ttttcttagc accgatagca gctccacgag
    12781 aaactgtcaa aatcgttcct tcaacaggtt tcatcactgc cttataggca acttccacac
    12841 ctgattggaa ggccagagcc aagtcttgac ctgttaactc gtctttatcc ttgatagctt
    12901 gggaaaatcc acggaaaagc tgagacgtaa tcactcctga gttcccacgc gcacccatca
    12961 aaagcccttt ggcaagaatg ctcgctactt ctccaactgt agaagctggc ttgtctgcaa
    13021 cttctttagc accattttca atggtcattc ccatatttgt cccagtatct ccatctggaa
    13081 ctggaaagac gtttaatgaa ttgacatatt cagcttgctt attcaagcga gttgatgcag
    13141 cctgcaccat ttcttgaaat aagctagtag taatttttga cacggttatt ctcctacaac
    13201 tttgatattt tgaatgtaga catttacagt ctgagcagta attccaagct ggttttccaa
    13261 gctaaaggca acacgctctt gaatgttttt tgacacttca ctaatctttg ttccgtagct
    13321 taacacggta tatacatcaa ctgcaatact gccatcttcg gctgccttta cgacgacacc
    13381 tttagaataa ttttccttac ctagcagggc ttggaaatta tctttgaggg catttttact
    13441 agccataccg accacaccaa aaatctcagt tgctgctcca cctacgacgg ttgcaatcac
    13501 ttcatctgtt agttcgattt gaccatcttt tgtattaatt tttacagtca tcctttttac
    13561 ctcaactagt tgatactcta ttttatcata tttcagccca agtgtaaaag cagaatgatg
    13621 tatcagcgga tatttactct atttttcaaa cgatgttata cccacaataa aagaaaaaag
    13681 accctaaggt ctcctttgct tttattatta aacgcgttca actttacctg atttcaaagc
    13741 acgagctgaa gcccaaactt ttttaggttt accatcgata agaacagtaa ctttttgaag
    13801 gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt ttcctgatac
    13861 agtcttacga cctgtaaagt aacatacttt agccattgtg ttttcctcct attagatcta
    13921 atatagcgga tgtgctagca ccacataccg tactatgtta tcacactttc ttgttttttg
    13981 caagggaatt ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg acattttctg
    14041 ctctccacat gccatcgttg attaacagaa caccagaatt aaaattatgt gtataaaaat
    14101 catctctaac tgcagctaag ggtatagccg tcaagtccaa atcccacagc tcatctatcg
    14161 attttcttac aacaatatct gaatccaaat acagtacacg agactcgctt acatactttg
    14221 gaataaaata cctaaaaaag ccgcatatga aagtccctca aaggggagac gataaccttt
    14281 cagaatacta ctgtcaatct aaacattcac aatctcacta ttcaaagtct ctagtctttt
    14341 ttccattaat tggaaccatt ctcgcggaag gtcatcatta aaaacataaa acttaagatt
    14401 ataatgatga acacaaagag attttattgt tgtttcaact ttatccatat aagcattatc
    14461 tgcacctaag acaatcgctt ttttctcttc tttcactttt tatctcattt ctttttattc
    14521 ccatcatatg tttctacgta accattattt tcgcctattc gttcgtaaaa ccataccagt
    14581 ggagatttta gatgaagtcc cattacggtt tacaattttt acattacgac acagagtttt
    14641 acaaatcgat ttcatttgcc aaacgtagtt agtaaggcag ttagctaggc tacctacttt
    14701 ctgctacgac ggaaaaatcc acaaatcaat accattcgtg gatttttcct agtgaagcgt
    14761 ttaggtaagc cgccatagcg gttaccgatt attagattac gacacggagt ttggcaaatc
    14821 gattctattt gccaaacgta gttagtgagg cagttagcta gttcgccaaa tagcgactag
    14881 cgtccaacaa tttggaactt tagttccaat tgttggtact gagtcacatc ttctcctcta
    14941 actctacgtc tggatacttg tccgcaaacc agcggagggc aaagtcattt tcaaagagaa
    15001 agactggttg gtcaaaacgg tctttggcta agatattgcg acttgacgac atccgttcat
    15061 ccaagtcctc aggcttgatc caacgaacgg tctttttacc cattgggctc atgaccactt
    15121 ccgcattgta ttcgccttcc atacggtgtt taaagacttc aaactggagt tgaccaacag
    15181 ctcccagcat gtactcacct gtttggtaat tcttataaag ctgaacggct ccttcttgca
    15241 ccaattgctc aatccccttg tggaaggatt tttgcttcat aacattctta gcagaaactt
    15301 tcatgaaaat ttcaggagta aaggttggca atggttcaaa ttcaaacttg ttttttccaa
    15361 ccgtcaaggt atccccaacc tgataagtac cggtatcgta aaccccgata atatcacctg
    15421 ccacggcatt ggtcacattc tcacgactct ccgccataaa ctgggtaaca ttagatagtt
    15481 tagccccctt accagtacga gggagattga cactcatgcc gcgctcaaat tcgcctgata
    15541 cgatacggac aaaggcaata cggtcacggt gacgaggatc catgttggct tggattttaa
    15601 agacaaagcc tgagaaatcc ttgtcataag gatccacaat ttcaccatct gttttcttgt
    15661 gaccatgtgg ttctggagca aacttgagga agatttcaag gaaggtctgc acaccaaagt
    15721 ttgtcagggc tgaaccgaaa aagacaggcg tcaattctcc agccagaata gcttcctctg
    15781 aaaactcatt cccagcttca tttaaaagct caatgtcatc cttgacttgc tcgtagaaag
    15841 gattgctacc aaaaagtttg tctccatctt ctaggctagc aaaacgctca tcccctttat
    15901 aaagttctaa acgttggtta tagaggtcat acaagccctc aaaggctttc cccatcccga
    15961 taggccagtt catagggtag ctagcaatgc ccaagatttc ttccaattct tgcaagagtt
    16021 ccaaaggctc acgaccgtca cggtccagct tgttcataaa ggtaaagact ggaatgccac
    16081 gatgtttcac aacctcaaac aatttcttgg tttgagcctc gatccccttg gcagagtcca
    16141 cgaccatgac cgcagcatcc accgccatca aggtacgata ggtatcttct gagaagtcct
    16201 cgtgccctgg cgtgtctaag atattcacgc gcttgccgtc gtagtcaaat tgcataacag
    16261 atgaagtaac agaaatccca cgttgcttct cgatatccat ccagtcagat ttagcaaaag
    16321 tccctgtttt cttccctttt accgtaccag cctcacgaat ctcaccccca aagtagagta
    16381 actgctcagt gatggttgtt ttccccgcgt ccgggtggga gataatggca aaggtacgac
    16441 gtttcttaat ttcttcttga atattcataa gttctctttc tttgattctc tatttttctt
    16501 gtttcaatag ctgagaatga tttttacatt ggattttacc attcctttca atactccatt
    16561 atatcggatt ttagcatttt tttcaatttc tatttctttt cacttccccc tcccttattt
    16621 ataggaaaat atggtaaaat agaacagact aaaaatcatc atttcacgaa aggatgcaag
    16681 atgaaaatta cgcaagaaga ggtaacacac gttgccaatc tttcaaaatt aagattctct
    16741 gaagaagaaa ctgctgcctt tgcgaccacc ttgtctaaga ttgttgacat ggttgaattg
    16801 ctgggcgaag ttgacacaac tggtgtcgca cctactacga ctatggctga ccgcaagact
    16861 gtactccgcc ctgatgtggc cgaagaagga atagaccgtg atcgcttgtt taaaaacgta
    16921 cctgaaaaag acaactacta tatcaaggtg ccagctatcc tagacaatgg aggagatgcc
    16981 taatgacttt taacaataaa actattgaag agttgcacaa tctccttgtc tctaaggaaa
    17041 tttctgcaac agaattgacc caagcaacac ttgaaaatat caagtctcgt gaggaagccc
    17101 tcaattcatt tgtcaccatc gctgaggagc aagctcttgt tcaagctaaa gccattgatg
    17161 aagctggaat tgatgctgac aatgtccttt caggaattcc acttgctgtt aaggataaca
    17221 tctctacaga cggtattctc acaactgctg cctcaaaaat gctctacaac tatgagccaa
    17281 tctttgatgc gacagctgtt gccaatgcaa aaaccaaggg catgattgtc gttggaaaga
    17341 ccaacatgga cgaatttgct atgggtggtt caggtgaaac ttcacactac ggagcaacta
    17401 aaaacgcttg ggaccacagc aaggttcctg gtgggtcatc aagtggttct gccgcagctg
    17461 tagcctcagg acaagttcgc ttgtcacttg gttctgatac tggtggttcc atccgccaac
    17521 ctgctgcctt caacggaatc gttggtctca aaccaaccta cggaacagtt tcacgtttcg
    17581 gtctcattgc ctttggcagc tcattagacc agattggacc ttttgctcct actgttaagg
    17641 aaaatgccct cttgctcaac gctattgcca gcgaagatgc taaagactct acttctgctc
    17701 atgtccgcat cgccgacttt acttcaaaaa tcggccaaga catcaagggt atgaaaatcg
    17761 ctttgcctaa ggaatacctc ggtgaaggaa ttaacccaga ggttaaggaa accattcaaa
    17821 gtgccgctaa acactttgaa aaacttggtg ctattgtcga agaagtcagc cttcctcact
    17881 ctaaatacgg agttgccgta tactacatca tcgcttcatc agaagcttca tcaaacttgc
    17941 aacgctttga cggtatccgt tacggctatc gcgcagaaga tgcaaccaac cttgatgaaa
    18001 tctatgtaaa cagccgaagc caaggctttg gtgaagaggt aaaacgtcgt atcatgctgg
    18061 gtactttcag tctttcatca ggttactatg atgcctacta caaaaaggct ggtcaagtcc
    18121 gtaccctcat cattcaagat ttcgaaaaag tcttcgcgga ttacgatttg attttgggtc
    18181 caactgctcc aagtgttgcc tatgacttgg attctctcaa ccatgaccca gttgccatgt
    18241 acttagccga cctattgacc atacctgtaa acttggcagg actgcctgga atttcgattc
    18301 ctgctggatt ctctcaaggt ctacctgtcg gactccaatt gattggtccc aagtactctg
    18361 aggaaaccat ttaccaagct gctgctgctt ttgaagcaac aacagactac cacaaacaac
    18421 aacccgtgat ttttggaggt gacaactaat gaactttgaa acagtcatcg gacttgaagt
    18481 ccacgtagag ctcaacacca attcaaaaat cttctcacct acttctgccc actttggaaa
    18541 tgaccaaaat gccaacacta acgtgattga ctggtctttc ccaggagttc taccagttct
    18601 caataaaggg gttgttgatg ccggtatcaa ggctgctctt gccctcaaca tggacatcca
    18661 caaaaagatg cactttgacc gcaagaacta cttctatcct gataacccca aagcctacca
    18721 aatttctcaa tttgatgaac caatcggata taatggctgg attgaagtca aactagaaga
    18781 cggtacgacc aagaaaatcg gtatcgaacg tgcccaccta gaggaagacg ctggtaaaaa
    18841 cacccatggt acagatggct actcttatgt tgacctcaac cgccaagggg ttcccttgat
    18901 tgagattgta tctgaggcag atatgcgttc tcctgaagaa gcctatgctt atctgacagc
    18961 cctcaaggaa gttatccagt acgctggcat ttctgacgtt aagatggagg aaggttcgat
    19021 gcgtgtggat gccaacatct cccttcgtcc ttatggtcaa gagaaattcg gtaccaagac
    19081 tgaattgaag aacctcaact ccttctcaaa cgttcgcaag gggcttgaat acgaaatcca
    19141 acgtcaagct gaaatacttc gctcaggtgg tcaaattcgc caagaaacac gccgttacga
    19201 tgaagctaac aaaacaacca tcctcatgcg tgtcaaggaa ggggctgcag actaccgcta
    19261 cttcccagaa ccagacctac ccctctttga aatttctgac gagtggattg aggaaatgcg
    19321 gactgagttg ccagagtttc caaaagaacg tcgtgcgcgt tatgtatctg accttggttt
    19381 atcagactac gatgctagtc agttgactgc taataaagtc acttctgatt tctttgaaaa
    19441 agctgttgcc ctaggtggtg atgccaaaca agtctctaac tggctccaag gggaaatcgc
    19501 tcagttcttg aatgctgaag gtaaaacact ggaacaaatc gaattgacac cagaaaactt
    19561 ggttgaaatg attgccatca tcgaagacgg tactatttca tctaagattg ccaagaaagt
    19621 ctttgtccac ctagctaaaa atggcggtgg cgcgcgtgaa tacgtggaaa aagcaggtat
    19681 ggttcaaatt tcagatccag ctatcttgat cccaatcatc caccaagtct ttgccgataa
    19741 cgaagctgct gttgccgact tcaagtcagg caaacgtaac gccgacaagg ccttcacagg
    19801 attccttatg aaggcaacca aaggccaagc caacccacaa gttgccctta aactacttgc
    19861 acaggaattg gcgaagttga aagaaaacta gacagaacaa aaccagccct aaggttggtt
    19921 ttttcttctc taccaactcc caataactat tttggcttta tttccagagt attttatggt
    19981 aaaatgaaga gtaataatat ttattaaaga ggtaaaaaca tgattgaagc aagtaaatta
    20041 aaagctggta tgacctttga aacagctgac ggcaaattga ttcgcgtttt ggaagctagt
    20101 caccacaaac caggtaaagg aaacacgatc atgcgtatga aattgcgtga tgtccgtact
    20161 ggttctacat ttgacacaag ctaccgtcca gaggaaaaat ttgaacaagc tattatcgag
    20221 actgtcccag ctcaatactt gtacaaaatg gatgacacag catacttcat gaatacagaa
    20281 acttacgacc aatacgaaat ccctgtagtc aatgttgaaa acgaattgct ttacatcctt
    20341 gaaaactctg atgtgaaaat ccaattctac ggaactgaag tgatcggtgt caccgttcct
    20401 actactgttg agttgacagt tgctgaaact caaccatcta tcaaaggtgc tactgttaca
    20461 ggttctggta aaccagcaac gatggaaact ggacttgtcg taaacgttcc agacttcatc
    20521 gaagcaggac aaaaactcgt tatcaacact gcagaaggaa cttacgtttc tcgtgcctaa
    20581 tctctagaaa gaggtcattc tatgggaatt gaagaacaac ttggcgaaat cgttatcgcc
    20641 ccacgtgtac ttgaaaaaat cattgctatc gctactgcaa aggtagaggg tgttcactct
    20701 ttttcaaaca gatcagtgtc tgataccctt tcaaaacttt cactcggccg tggcatttat
    20761 cttaaaaacg tggacgaaga actcacagca gatatctatc tctaccttga gtacggagta
    20821 aaagttccta aggtagcggt tgctatccag aaagctgtca aagatgccgt ccgtaatatg
    20881 gctgatgtag aactcgctgc tatcaatatt cacgttgcag gtatcgtccc agataaaaca
    20941 ccaaaaccag aattgaaaga tctatttgac gaggacttcc tcaatgacta gtccactatt
    21001 agaatctaga cgccaactcc gtaaatgcgc ttttcaagct ctcatgagcc ttgagttcgg
    21061 tacggatgtc gaaactgctt gtcgtttcgc ctatactcat gatcgtgaag atacggatgt
    21121 acaacttcca gcctttttga tagacctcgt ttctggtgtt caagctaaaa aggaagaact
    21181 agataagcaa atcactcagc atttaaaagc aggttggacc attgaacgct taacgctcgt
    21241 ggagagaaac ctccttcgct tgggagtctt tgaaatcact tcatttgaca ctcctcagct
    21301 ggttgctgtt aatgaagcta tcgagcttgc aaaggacttc tccgatcaaa aatctgcccg
    21361 ttttatcaat ggactgctca gccagtttgt aacagaagaa caataaaaag aaaaagtgtt
    21421 tgatagatat caaacacttt tttctttgcc tcccactatc taaaaaaatg ataatagata
    21481 taattgtaaa caaaaatcca gataggtttt gcatgattga gaaagttaaa aaaactatgg
    21541 cagagaatcg ttaatctcag attgtcggta gaacgataaa caagggcaaa aaagaaacca
    21601 atcagactat aatataataa actaattgga tctctgtgag atagtatcaa atggctaatc
    21661 ccaaagatga tagcagatag gataacatcc aaatagtact tggactaggg aaagaaggta
    21721 ttcataaaat accctctatc aagagtctcc tcaaaaacag gaccgatgat tacaggcagg
    21781 acaaaagata agatagtcga taaaaaggtt ggttgtccat ttgaaaaaag cacggtaaaa
    21841 tactcatcat gaatattcct atgattaatc aaatgagcat agcgtgccca aaaattaccg
    21901 agaatctgat aaaccacata agttgcaaat aagtagaaga caaatgacca gttccagctc
    21961 tttttctcaa agataaagag catctttttc ttttttaacc tccaaattat atagaaggaa
    22021 acttcccact aatcccattg ttaaaataag agaatagaca tcagctccta accctaaaat
    22081 gatcgtcaca tacaatccaa ttgtttgtgg taaataggta gatagtaaaa taataagcaa
    22141 aaatattcca aattgtctta gtttttttgt gtttctcatc gtactttttt gaaagattac
    22201 cctgctcgga agccgtactt ccaagcatct atataagaat taagtgcccc ttgcctcata
    22261 tagggagcaa attctctata atataaccat ctactatatc catcttccca aacagcaaga
    22321 ccacctgaag tttgctccaa gtcctcagtt gaaagaactg taaatgtatt tgtacctgtc
    22381 attgcaagta ccttcttaaa atagattgtt gtaggctcac atttatagta tatttctttt
    22441 tttgtctatt ttatagccca tctcctcaac tggcaatttt tcgacctgaa ttacattttt
    22501 ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt
    22561 gatagcgttc ttccagcaac tcttctagcg gtttttgtga aaatctagcc agctccgttt
    22621 ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctatt tcagaaatca
    22681 ccttatccac cacgtccatt tctaacagtt catgcgaagt gattttcatc agttctgctg
    22741 cttccatggc gcgagtaccg tccttccata aaatggaagc aaagccttct ggactgagaa
    22801 tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga gccagagccc
    22861 cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg tcactcattt
    22921 ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttctgctccg acaccaggat
    22981 aagcacctgc tgtattaata aaggtcacaa ctggacggcc aaatttctca gcctgtttca
    23041 tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc cgtttgaggt
    23101 tgtcttgcaa actcttgcct ttttggatac caacaactgt tacagcttgg tctccaagcc
    23161 aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca tgtaattgga
    23221 taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg
    23281 cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc tgactaggct
    23341 agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc catgttctaa
    23401 taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat tttcaatcac
    23461 acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat cgccttccat
    23521 agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca ggtaaaagag
    23581 accagcattt gaatgacgtt taaccgccgc agagatctta gccatctgca tgagactcat
    23641 gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg gcaatttttc
    23701 gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac ccatagaagc
    23761 catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa taagagcagt
    23821 tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca gtttcttttg
    23881 gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt ctttgaaggt
    23941 tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg tatagctaca
    24001 gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct tacagcctgg
    24061 acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt ccctaaccga
    24121 acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca ttgattcccc
    24181 ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag gtaagaaggt
    24241 ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg aaatgaggtc
    24301 aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga gggcacgttg
    24361 cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg caatcatact
    24421 atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc gcaagccaac
    24481 tccaccactt ggcagataga gattagtaat cttacctgga cttggagcaa agttaaaggc
    24541 tgggttttct gcattgatac gacactcgat ggcatgaccg cgtaggacaa tatcttcttg
    24601 cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga tatcaacacc
    24661 tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct ccatgaaata
    24721 gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct catagccaac
    24781 aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt ttccgattgc
    24841 aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac aatcccgctc
    24901 acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa tgtgccgagc
    24961 tggatagata acccgttcta tgtacatggc accattgcca taattggcct tggcctcact
    25021 agaggcagtt tcaaaggcag aaacgaggtc atctggtttt tcaaccttac gaatcccttt
    25081 accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt cagcaacaat
    25141 caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag gcacacctgc
    25201 tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa catgaccaga
    25261 tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg aattttcact
    25321 gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag ctgatagaac
    25381 tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa ctgcttcatc
    25441 tgccaaaagc gtatgaagag cttccttatc agcagttgaa taaaccgcta ccgtcgcaat
    25501 ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat tggcaattaa
    25561 aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag gataccactg
    25621 gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt gccacgacgt
    25681 tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt cttgaactta
    25741 accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt tgataactcc
    25801 aacacaccag cagtttgcgc caaggcttcc ataatcagaa cacctggcat aactgggtat
    25861 tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat agcaacaatg
    25921 gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg gtggggaaga
    25981 gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta ccaaactcaa
    26041 ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga gctgggattt
    26101 cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg acactatcac
    26161 caactgtaac gaaggcaggt ttatctggtc cagcagccaa gtaaaccact ccaacaagtg
    26221 gactctctac aagatttccc tcactagcca cacttgcttc agctggagct ggaacttctt
    26281 ctgctacagt ctctgctgga gcagatgtag gagctactgg actcggtgtt gctagaacgg
    26341 gtgctggagc gacttgagtt gcaacttcag gcacaggtct cgcttcattc ttgctaaact
    26401 gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg tcaaattgag
    26461 tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac gtttgaaagc
    26521 aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg gaatttcttt
    26581 ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt cacttgtccc
    26641 agctgtcatt ggtacaaagt tatgacgcat agcttcgatg gtgacgatag cttctactgc
    26701 acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag gtacttcctt
    26761 accaagaaca gctacgatag caccactttc tcctttttca ttggcaggag ttgacgttcc
    26821 gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca aggctagttt
    26881 gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt aggcatcaca
    26941 agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt cagcgtgttc
    27001 aagactttct agaaccaaca tccctgaacc ttcacccata acaaacccat tgcgatcctt
    27061 atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg ttaaggcttg
    27121 gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca acatcacatc
    27181 ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg atgaagagca
    27241 ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga
    27301 agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg gtcctttttc
    27361 atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag atgcaacgat
    27421 aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat ttacagcctc
    27481 ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat ctttttttac
    27541 aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat caaagtcact
    27601 atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac tattccaaaa
    27661 ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca ctactcgatt
    27721 tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat caatggcaac
    27781 cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg caacctgctc
    27841 tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa tcttatctga
    27901 taagatagct gtcatatcag actcaatcat tcctggagca atcacattga ctcgtatatt
    27961 ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag ccttagaagc
    28021 agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca tattaatgat
    28081 agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat taaaggcacc
    28141 agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga gcataagagt
    28201 atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt ctgcaatagc
    28261 ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa tgggaaccac
    28321 cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc cacgactgtt
    28381 taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac caattccacg
    28441 actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc tttcaaaact
    28501 tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat cttccacatg
    28561 agctaagtga gcagtttgat caattttttt aacaaaacct gacaagactt tccccggtcc
    28621 aatctcgata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt catagaaacg
    28681 aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc
    28741 agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct gagctagagt
    28801 ttcagctagt ttctggctag caggctcaag gagagcggtg tgaaagggcc ctgacacctt
    28861 aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc
    28921 aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg gagtaaccac
    28981 tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg tattgagaac
    29041 tgctaccatc ttgccagagt cagcaggagc cgcttcttcc atataggctc cacgcttagc
    29101 taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg cagagtattc
    29161 tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca ataaacggta
    29221 gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc
    29281 ttcttccgta tcgatgagat aacgtaaatc ataaccgagc acctgactcg ctcgatcaat
    29341 cgtttctttg acaatcggat actgatcata gaaatcccgt cccatcccta gatactgggc
    29401 accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct gcccagcgag
    29461 aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg atttcttcag
    29521 ctgtttcttc tttagaaaca agccctgcga tttgacctgc catgacagag ccaccatcca
    29581 catcaccgtg aacaactgct ttggctaggg cacctgctcc catttgttca aagatttcta
    29641 aatcaggatc ttcctgctta aaggcatctt tttcagccag ttcaaaatct ctagtcaact
    29701 gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat
    29761 cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct tttgcaacta
    29821 caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc gcagcacctt
    29881 caccatccgc aattcctcct gcagcaataa caggaataga tatagctgtg gctacctgtc
    29941 gcaccaaggt catggttgtt aatttaccga tatgcccccc agcttccatt ccttctgcaa
    30001 taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcgacacta ggaacaacag
    30061 gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga tttcctgctc
    30121 ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct tccacaaagg
    30181 gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg attttatcaa
    30241 tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct aatcctccag
    30301 ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct ccttggaaaa
    30361 taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct ccaaccttcc
    30421 ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta cctaaacaag
    30481 agggagtggg tttctcccta ctccttctac taatattctg cttattttgc ttgctcttca
    30541 acgtaagcaa ccaagtcacc aactgttttc aagtcatttt ctgcttcgat ttggatatca
    30601 aaagcatctt cgatttctga gattacttgg aacaagtcca atgaatctgc gtccaaatca
    30661 tcaaaagttg attcaagtgt tacttctgat gcgtcttttc caagttcttc aacgataatt
    30721 tcttgtactt tttcaaatac tgccatgata ggactccttt aaaataaata gtttttttat
    30781 aacaatgtgt tcaccacatg attacctaaa ttgtaagaat gagcgtgccc caggtcaagc
    30841 ctccaccgaa gcctgataga agaacagtct ggctaccatc taaagggatg agaccttgtt
    30901 ctacacactc tgaaagtaaa atcgggatac tggctgcact ggtattgcca tattccatca
    30961 tattggctgg aagtttggct cggtcaacac caatttttct agccatctta tccaaaatac
    31021 ggtcattggc ttgatgaagt agcagataat ccaagtctgt cacctctata ggagattcat
    31081 caatagtctg cttgatagac ttggctacat ctcgaatggc aaaatcaaag actgtgcgtc
    31141 catccatctt caaaaacgaa tctgcacttt cttgatctga aaatggagaa tgcaaacctg
    31201 aatgcccata agttaaacac tcgctgcgac ttccatcgct attgagactc tcagctaaga
    31261 aatgctcttg ctcgctagct tctaacaaga caccaccagc accatctcca aacaacacag
    31321 ctgttgatcg atccgaccaa tcgactgcct tagagagggt ttcactacca atcaccaagc
    31381 ctttttgaaa gcgaccagaa gcgataaact tttcagcagt tgaaagagca aatacaaatc
    31441 cactgcaagc cgcggttaag tcaaaagcaa aggctttatt agcgccaata ttagcttgaa
    31501 cacgagcagc tgtagagggc atcatcgaat ctggagtaat ggtagctagg atgataaaat
    31561 ccagttcttt tcctgttatt ccagcttttg ccatcagttt cttagcaacc tctgtagcca
    31621 aatcactggt agattctgtt cttgaaatat gcctttgtcg tattcccgtt cgacttgaaa
    31681 tccactcatc attggtatcc ataatctgag ccaagtcgtg atttgtaacc acttgctctg
    31741 gcacataatg agcaacctga cttatttttg caaaagccat tatttcaaat cctccaaaaa
    31801 ttggtaaaga ttagtcaagc ctttacccat gacagcaatt tcttcctcgc tcatgccatc
    31861 aataattttt tctaccatgg ccttgtggaa gcgtttatgc agtctatgaa tcaagcgacc
    31921 cttctttgtc aaatgcagat gcaccacacg acgatcctgt tctgaccgaa ctcgctcaat
    31981 gtagccctta cgctctaaat tgttcaaact tgtcgtaaca gttccaagag ttaccatcaa
    32041 ctcttttgac acttgacttg gagtcacatc tggagcctta ccgatgacat caatcgtatg
    32101 catttctttg atggagatat ccttaaaacg actacctctc aagttcactt cctcaattac
    32161 aaggacattg ttaaatatag atgttaaata ttcattgatt cgttggtagt ccatttttca
    32221 tatccctcct tcttcaaaaa acttttacaa tcaaaacatt tgacagaaag aattatatca
    32281 aaattcaaag aatgatgcaa gtatttttta ttttcctgta aatttaggtc ttcttctctc
    32341 cgaatgagct cgcactcctt ctttgaaatc ctctgtttga gctaaggatt tctgtaggtt
    32401 cagttctaaa gtagcgtaac cctgccagtc tttaaactgg ctctcccaaa ccaacttctt
    32461 aatggcagca taggaattac ttgaagcacg tcttaatttt ttaagaagct gttctctcgt
    32521 cttttcaagt ttttcagctt cagaaacgcg gtaaaccaac ccccattcta gggctttttc
    32581 tgccgttaaa gcctctcctg tcatagctaa ttgagcagca cgcgtcacac cgatactgcg
    32641 gctcaagaga tgaattcccc ctgcatctgg agccaaacca acaccaacaa aggcttggat
    32701 aaacttagcc ttatccgtcg ccaaacagaa atctgccgca acagccatat tcgctgcggc
    32761 acctgcaaca gcaccgtcaa cttccattaa aacaggtttg gctatttgct tgattttata
    32821 agaaatcgta ttgaccaact ctgcgatttt tgtcaatgat ggaatatcat cctcatccac
    32881 tgcccgcttc atctctacca aatctccccc aactgagaag acctttccat tggcattgat
    32941 taagataaaa tgcacagctg gattttcttc tgccaaagtc agagcttcta aaatctcctc
    33001 acacatggga atatgaaaac catttgcgac ctcaggacgg ttcaaggtaa ggattgccaa
    33061 gtcctcttca agctgataaa taatgtgttc catcagggct cctttttatt ttataagcag
    33121 tttatactct tcgaaaatct ctttaaaccg cgtcagcttc catctgcaac ctcaaaacag
    33181 tattttgagc tgacttcggc tagcttccta gtttgctctt tgattttcat tgagtgttaa
    33241 attatttcac tgtcaaagta tatctttttt aggagcagaa agcaagaaaa aatcgactga
    33301 aagtgtctca gccgataaga aaggctcgct ttaggctaga aagcatctta ttttcttcat
    33361 tgaaaaaagc ctttctttct gctataatcg tataaaatac ttactttagg agttcttatg
    33421 aaagttgtta aatttggagg tagttctctt gcctctgcta gtcaattaga aaaagtttta
    33481 aacatcgtca aaagcgattc agagcgtcgt tttgtagtcg tttctgcgcc tggtaaacgc
    33541 aatgctgaag atactaaggt tacggatgcc ctgattaaat actaccgcga ctatgttgcg
    33601 ggtaacgata ttagcaagag ccaaagctgg attatcgacc gctatgctgc tatggttagt
    33661 gaattgggac taaaaccagc tgtgctagaa aaaatttcta aaagcattca cgccttggcc
    33721 actcttccta ttgaagaaaa tgaatttctc tacgatactt tcctagcagc cggtgaaaat
    33781 aacaatgcca aattgattgc tgcctacttt aaccaaaatg gtatcgatgc acgctatatg
    33841 caccctagag aagctgggat tgtggtcaca agtgaacctg gtcacgctcg catcattcca
    33901 tcaagttatg acaagattga agaattgaca aacaccaatg aagtccttgt cattcctggt
    33961 ttctttggtg tcactaagga aaatcaaatc tgtactttct cacgtggagg ttctgatatt
    34021 acaggttcta tcattgctgc tggtgtcaaa gctgacctct atgaaaactt tacggacgtt
    34081 gatggtatct ttgcagccca ccctggtatt atccaccaac cacactcgat tcctgagttg
    34141 acctaccgtg aaatgcgcga gttggcctat gcaggcttct cagtccttca tgacgaggct
    34201 cttcttcctg cctaccgtgg aaaaattcct ctggttatca agaataccaa caaccctgac
    34261 catccaggta ctcgtatcgt tctaaaacac agtaatgatg aatttccagt tgtgggaatt
    34321 gctggtgact caggctttgt cagcattaac atgtcgaaat acctcatgaa ccgtgaggtt
    34381 ggatttggcc gcaaggttct gcaaatcctg gaagaactta acatcggttg ggaacatatg
    34441 ccaacaggta tcgacgatct ttctatcatt ctccgttctc gccaactaac tcccatcaag
    34501 gaagaagaaa tcctgcgtca gttggttcaa aaggctaaag tagatcatgc agaaatcgaa
    34561 cacgaccttt ctatcattat gattgttggt gaaaaaatga agagccacat cggagtgact
    34621 gctactgcga cacgcgctct atctgaaaac aaaatcaaca tccagatgat gtctcaaggt
    34681 tctagtgaag tttctattat gtttgttgtc aataaagacc aagagaaagc agcaattaaa
    34741 gccctctaca atgccttttt tggagaaagt aaggaagact aagcatggcc caatcactta
    34801 acaaaacagt actcctcagt acgacaggca cttcctacct ctctatcgct gggaaagttg
    34861 ggaaattcct tgtcggagat caggctttgg aattttaccc agatgtcaat gtcgaacaat
    34921 ttatccagat tccttggagc catatcaatc agattggagc caatgtcact ggatgcaaaa
    34981 tcagccgcca cttcgaagtc tttacagaca aaggaaaatt cctctttgct tcaaaagact
    35041 caggtgccat tctcaaaatt gcacgcgaaa aactaggcaa tgacaaggtc gtcaaacttc
    35101 cgaccctgat tcagacaatt agccaaaaat ttaaaaatct atttgcaaaa aagtagaaac
    35161 tttagtataa tcatagcaac ggataagtag gttatcttct tctttcagaa agtctgcggg
    35221 tactgcgagc agataggagg gataggtgaa attctaccgt tagtaacaat tacatacaca
    35281 atcaagtgca cacctgtgaa gttggatgga accgtggccc tgccactcca acgttttgtc
    35341 aggcgtgctt ttttcataaa ggagttctta tgttagatat caaacgtatt cgtacagatt
    35401 ttgaagctgt cgcagaaaaa ttagctacac gtggtgtaga tgctgctgtc ttgaatgaaa
    35461 tgaaagaaat cgatgctaaa cgtcgtaaca tcttggtcaa ggttgaaact ctcaaagcag
    35521 aacgtaacac agtttctgct gagattgccc aagctaagcg caacaaggaa aatacagatg
    35581 acaagattgc tgccatgcaa aatctatctg ctgaggttaa agccttggat gctgaattgg
    35641 cagaaatcga tactaaattg acagaattta caacgactct tccaaatatc ccagctgaca
    35701 gcgttcctgt tggggctgac gaagacgaca atgtggaagt tcgccgttgg ggtactccac
    35761 gcgagtttga cttcgaacct aaagctcact gggatctcgg tgaagacctt ggtatccttg
    35821 actgggaacg cggtggtaag gtaacaggcg ctcgcttcct cttctataaa ggcctcggtg
    35881 ctcgtttgga acgtgctatc tacaacttta tgttggatga acatggaaaa gaaggctata
    35941 ctgaagtcat cacaccttac atagtcaacc atgattctat gtttggtact ggtcagtatc
    36001 caaaatttaa ggaagatact tttgaactca gcgataccaa ctttgtcttg attccaactg
    36061 ctgaagttcc tctgacaaac tactaccgtg atgaaatctt agacggcaaa gatcttccaa
    36121 tctacttcac tgctatgagt ccgtcattcc gttctgaggc tggttctgcc ggtcgtgata
    36181 cgcgtggctt gatccgtttg caccaattcc acaaggttga aatggtcaaa tttgccaaac
    36241 cagaagaatc ttacgaagaa ttggaaaaaa tgacagccaa cgctgaaaac attcttcaaa
    36301 aactcaacct tccataccgt gtcgttgctc tctctactgg agatatgggc ttctcagctg
    36361 cgaagactta cgacttggaa gtgtggattc cagcacaaaa caattaccgt gaaatctcaa
    36421 gctgttcaaa cacagaagat ttccaagccc gtcgtgccca aatccgttac cgtgatgaag
    36481 cagatggcaa ggtgaaactc cttcatacct tgaacggttc tggacttgca gttggacgta
    36541 cagtggctgc aattcttgaa aattaccaaa atgaagatgg ttctgtgacc atcccagaag
    36601 cacttcgtcc atacatgggt ggagctgaag tcatcaaacc ataaaaaata aggtttagct
    36661 atttctagct agaccttttt tcgtaaccaa atcagataag cacctagtac aaagaataaa
    36721 atagttaggc atataatggt ttcagccaat accaggtaat ccagaaatgg aagtttcaaa
    36781 attccctgag ccatcttgag cgaggtcgct gtgataatgg ttgggaaggt gagggctgag
    36841 aaggctggtt gaaaaccttg ttttaaaatg ttgggcagac gagttaaaac aaagaaaaag
    36901 aaggattgag aagccaaaat catgacaatc aagacccaag tcggcaggct ggttcctcct
    36961 actcgaacta gagaagccaa gagtagagag aaaggagcac agtagattcc ttcttgtcca
    37021 agcaaggcta gtgggagtgg atgtttcttt aaatcgctat aaataagggg atagagatag
    37081 aaggtcaaga gaaaaccaaa actcaaggtc gcataggcaa tttcgataat acctaccaga
    37141 ggataggtca aggcagccac tgctatcccc acatagagaa ccgtccagct tggagtggca
    37201 tgaaccctcc gccctggaca agcaaacttg atggtaaaac cagcaatcaa ggtcaaatcc
    37261 aagagaaatg aaaaccacca aatcccttgt gctaccaaag gaagataaga gaatacgcga
    37321 aagacatagg tcgataaaat catcccagcc ataggaaagg ttgccattcc tgacaaaaga
    37381 gggggcttgg tcaattcttg cttggtttct ttccaattaa agagatgcag aattagaaag
    37441 taaatccata aaaccaaacc agtcagacta aaaagatggg atagaaccgg caacgtatct
    37501 aaaataagat ttccagctcc tgccaaacct agcaaacaac ctgaaaatac taaggggagt
    37561 tttttcatcc taacctccaa taatcatgtt agtttcagta taacataaaa gcgcttaaat
    37621 gaggatttaa aaaaacgaag tccgcttatt tcagacttca ttttactcag atatgaatta
    37681 ggcataaggt tgcaattctg gattaattgg tgtattagct aagttgttgg catagttaca
    37741 gaggattgct aggctgacac caaaaaccac atccaaggca ttttgttgag tgtagccagc
    37801 ttctaaaaac tcagacaagg cttcatctcc tacacgaccc ttggtattga taactgccaa
    37861 ggtaaactta gctagggtat ccaatttagg atctgtttca attggagtac gattgcgaag
    37921 agcttgaatc aagtcatcat tcatctggat ttgtttgatg gaaaaggctg tgtgacctgc
    37981 gacacagaag gcacaaccat tggtcacggc tgccgtgatt tgcaccactt cacgctcaac
    38041 gggtgtcagg ctgttgcgac ggtggataga tgagacaatt tggtaggctt ctaaaacagt
    38101 cggggcattg gccaagagac cgattaggtt gggaatatag ccattgttgt ctttttctac
    38161 tgtttcaaga atttctttca cttctgctgg tgctgactct actgtatgga tagtaaatgt
    38221 tgtcataaga tacctctttt cttattattg acactaatat tattggaaaa tcttataaaa
    38281 tcctgattcc taagtttatc taagataaag ctttattctc tcataagatt ttcgttgtta
    38341 tattagttta tcacacttcc aatcacttgc ataatatata ttatatatca ggctgataaa
    38401 aattatttat aggcaaaaaa atcacacgag ctgtgtgatt ccattatttg tcaaaatact
    38461 ttttagtttc agcaataacg actggcgaca agaccaagag ggcaatcaag tttggcagag
    38521 ccatcaaggc gttaacgata tctgcgataa tccagaccat atccaactcg ataaatcctc
    38581 ctaacaagac catgagcaca aaaaccacac ggtagagcca gataaagcga accccaaaga
    38641 ggaactcaaa acagcgttct ccgtaatagt tccaacctag aatcgttgta aaggcaaaaa
    38701 gtacaaggaa gatggtcaag agggcaggcc caaagtgtga aaagactgtt gagaaagctg
    38761 actgagtcaa ggcaacccca ttcaagtcac cactccaaac tccagttacc aagatggtca
    38821 aaccagttag agtacaaatg atgagggtat caataaaggt tcctgtcatg gaaatcaaac
    38881 cttgctctac tggttcattt gtcttggcag ctgcagctgc aataggagca gaacccagac
    38941 cagattcgtt tgagaacaca ccacgcgcca caccattttg aatagccatc cgaacgctag
    39001 caccagcaaa tccacctacc gcagcaaggg gactaaaagc tgaggtaaag actaaagcga
    39061 ttgtgccagg gatttttcca atattaaaga aaataactgt aagagttcct aagatataaa
    39121 tgatggccat aaaaggaaca acagtagttg aaaccttaga aatagacttg agtccaccaa
    39181 agactgcaat cgctacaaag acagacaaga cgagagctgt gatggctggc gaaatcgtcg
    39241 ttgtattttg gatagattct gcaatcgagt tgacttgggt gaaggttccg attcccaaga
    39301 gagcaaccaa tactcctgct actgcaaaca aaacagcaag tggtcgccac ttttctccca
    39361 tccctagaag gatataatgc atgggacctc ccgctactgc accatggtcg tccttggtgc
    39421 ggtatttgat ggccaagagt ccttccgcat acttggtagc cattccaaag aaagccgcca
    39481 tccacatcca aaatagagct cctggtccac caaccttgat agccgtcgca actcctatga
    39541 tatttcctgt tccaacagtt gatgccaagg ctgtacacag agctgcaaaa ctggatacat
    39601 caccatgtcc cttatcctgg ataaaaataa gctgaaaagc cttgggcaga cgcaaaacct
    39661 gcaagagtcc tagccgaata gttaggtaaa tccctgttcc gaccaataaa atcaagaggg
    39721 gcggtcccca agcaaaagca tcgattgatt taagcaattc taacatttcc ttctcctatc
    39781 gtttcaaccc caaaagaaag agcacatgca agatacatgt actctggaat gcttagataa
    39841 atgctaaaaa gcggtctatc ctagctctgt ccttttacct gagagtttga gcagttgcct
    39901 gccttgcccc ttcggtgcct ttacggtctc tccagagttc cgtccattta cagtcatgga
    39961 aaatcaaacg attccccact tctattaaac ttcattcggt gttggtattt aattgattct
    40021 aattttacaa aaaatgttgg cttttgtcaa tgtgtttaat tagtaaaaat tagttcaaca
    40081 gtttttactt tataaagtcc agaatactgc tatcctttaa aagtgacaat agtcgcacca
    40141 ctgcctccag cattttgtgg ggcatagccg aaactcttga catgtttgtt tctttgcaag
    40201 tatttggtaa ctccttcacg gatgactcct gttccgatac catggatgat atcaacttga
    40261 gccatattgt taagcaaggc ttggtcgatg aagatatcta gctcattcat ggcttcttca
    40321 tagcgcttgc ctcgaagatc cagtctagct tgaggtcctc gcccagaagt tcgtttcaca
    40381 acattgacct gcttcttctt gactggtttt tcttgctggg cttgaacaag atcaaactct
    40441 ttctcttcca aggtcatctt aatcaagcca acttgggctt cccagcggcc gtccttgagt
    40501 tgactggtca aggtaccacg ctgaccataa ctgagaacca cgatatcatc tcccaccttt
    40561 ggagctcgtt ttttcttggc cttttgaagg accttgtttt tagacaagtc cactttttca
    40621 ggagccaatt ttttcaactt ggccttggct tcaatgattt cgtggggctt gagttgggat
    40681 ttactgtgga gatttttgag aatctggtca ctttcactta gggccatatc cacaatctca
    40741 gcagcctgtt cacgcgcctt gttaagctcg gtttcctttt cacgattaag ctcgttgtag
    40801 agttttttta gcgcacggtt catcttgaga ttttcttgct ccacctcacg gatattgtcc
    40861 aaacgtttgc ggctttccag cgtctgctct tctaattgct caatgatacg attgacgtca
    40921 ttgtcctgat cgatctgctg actggcatct cctacgataa cttcagatag gcctagacgt
    40981 ttggcaattt caaaggcatt acttcggcca ggaacaccct gcataaagcg ataggtcggg
    41041 cgaagagttg cagtatcaaa ctccatactg gcattttgca caaaggctgt ctcaataccg
    41101 taggccttga gttctggata gtgggtcgtc gccatggtct tgatttgacg caggcgaagg
    41161 tcctccagaa tagccatggc aagggctgct ccctcttggg gatcagtacc agcccccagc
    41221 tcatccaaaa gtaagagtga atgttggttg accttgccaa gaatatccac gatattggtc
    41281 atatggctag agaaggtaga caagctctgc tcaatagact gctcatctcc aatatcagca
    41341 aagatttctt caaaaatacc aacacgactt cccttgtctg ctaaaatcgg caatcctgac
    41401 tgggccatga cctgtgtcaa gcccagagtt ttaagcatga tggtcttccc acctgtattg
    41461 ggacctgtaa tgacaatagc tgttaaatct tgaccaaaat ggacatcatt tgcgacggca
    41521 tttttgacca aaggatggca gacatggagc agttgaatct cttgattttc tgacagctga
    41581 ggcacgactg cttgtctttc ttggataaat cgaaccttgg cacgaatcaa gtccagatga
    41641 ccgataatcc aagcgtcatt agcaatctca gccgcatgag ggcggacacg ctcagaaatt
    41701 tcttggagaa tgcgaagcat ttcatagcgc tcatctgctc gcagactagc aatttcttcg
    41761 ctcagtttga ctacctcacg tggttcgata tagacggtgt ttccactagc agaaatatca
    41821 tgaacgacac ctgcaatctt attgcggtag gtgtttttga ctggtaaaac ctgacggcca
    41881 tttctgctag caacaattcc ttctgtcaac atctgcgctt tttgcttgag caagtcttgt
    41941 aaaacatcgc gtacctgact ctcgctatca tgtatttttc gacggattcg cgccaatttt
    42001 tcactggcaa aattttcaat gaaacccgca tcattaaagg cctgaagatt tccttgtaat
    42061 tgcggaaaat catgtaattt ctcaaaccaa agggctaatt cttccaagct gacattttcc
    42121 agattggcgt aaaaactttg aagttctcgg ctggcaagaa gcacgcgttt caagagtagg
    42181 aactcctcga tattgagatc cgctcccatc tccaacctct tgcagactcc tgcaatttcc
    42241 ttagttgaga gaatagtaaa atgcggttgc tcgacgaaaa gagcctgcat ttccttcatc
    42301 tcagcaaaag cctgtttgat tttatctgct ttggcagtcg gagccagttg tctcaattgc
    42361 tccaagccct gctcggtcaa caaatgaggc tcaaacaagg ccttgacctt atcgaactct
    42421 aatgtttcta atattttctt attcatcttt atttccttgt ctttgaatgt ctaggtgtgg
    42481 tagcttttta cattctgata gattcgagtc aaatctgtaa acaaagggct aggaaaactc
    42541 ctgccctttt tatccgatta aatttgtcac ccagatttgt ttgagccaac tggttgttat
    42601 cggtatgctc tggatgatgt gttttgcgac gatactcttt tcaagaggat tttgtataac
    42661 tgccatgggg atggtcgcca agattgtcaa ggccatttgc aagacaaata aggtcaccaa
    42721 catggacaag atacctgctg aaacttggaa caacttacca cccagttttt tgctaggaat
    42781 caagtgtaag agaagaccaa gcaaacgacc aatgctatag acaatcccaa atacaagcaa
    42841 gtagccgatg cctgcataaa agaccttatc cagctgaaag agttgatccg atgggaaaaa
    42901 gaaagtcccc tgaccttcct gcgaatttgc ataagggagc aataaatgga attgctctcc
    42961 aagcccctta taaaactggc cagccataaa agccgatgcc atggctgaaa tcaggtaata
    43021 aacctgtaag agcaggcctc tccgatagcc gatataaaat ccccaaacca agaccaatag
    43081 aagaaggaat gaaatcataa ggaatcctca atcttgctct gttcttgctt acaagtcaca
    43141 agcttgtgac ggagttcttc tagctcttgc tccttatcgt caaattcaat ctcacggctg
    43201 agctgagttg ataaacagtt gactgccaac aaaagagcga ttgtttcatc atctgcgcta
    43261 ggcatttgtt ctttaattgc ttggtatttt tctgtcgcaa ccttagcgat ttcctccata
    43321 aaaaggttat catgttcgct tgtcaaggtt aacgattttt tcccgaatgt aaatttgaat
    43381 cgatttagat ttgccataaa attcacctca cgatattata ccaaaattcg ctaattttgt
    43441 cagtttttac aaattttact gcttttgtgg tacaatagaa actatggcaa gtatcacact
    43501 cacaccaagc gaaaaggata ttcaggcttt tcttgaacac tatcaaacca gtctggctcc
    43561 tagcaagaat ccctatatcc gctacttttt gaaactacct caagcaacgg tttctatcta
    43621 tacttctgga aaaatcttgc ttcagggtga aggggctgaa aaatacgcca gtttctttgg
    43681 ctatcaagct gtagagcaaa ccagcggaca aaatcttcct ttaattggga cagatgaggt
    43741 gggaaatggt tcctactttg gtgggcttgc agttgtggct gcctttgtca cacctgacca
    43801 gcacgacttt ttacgaaaac tcggtgtggg ggattctaag actctgaccg accaaaagat
    43861 ccgtcagatt gctcctattc tcaaggaaaa aatccagcac caggcactcc ttctctcacc
    43921 cagcaagtac aacgaggtca tcggagaccg ctacaatgct gtttcggtta aggttgccct
    43981 ccataatcag gctatctatc tcctccttca aaaaggtgtt cagcctgaga aaattgtgat
    44041 tgatgccttt accagtgcta aaaattatga caagtacttg gcacaagagg ccaatcgttt
    44101 cagcaatcct atcagcttag aaaaaaaggc tgagggcaaa tacttggctg tcgcagtttc
    44161 ttctgtcatt gcgcgtgatc tctttctgga aaatcttgaa aatctgggac gagaactggg
    44221 ttatcagctc ccaagtggag ctggaacagc ttctgacaag gtggctagcc agattttgca
    44281 agcctatggt atgcagggac tcagcttctg cgccaaattg cactttaaaa acactgaaaa
    44341 agcgaaaaaa cgcttagaaa ggtaagttat gaattcattt aaaaatttct taaaagagtg
    44401 gggattgttc ctcctaattc tgtcattact agctttaagt cgtatctttt tttggagcaa
    44461 tgttcgcgta gaaggacatt ccatggatcc gaccctagcg gatggcgaaa ttctcttcgt
    44521 tgtaaaacac cttcctattg accgttttga tatcgtggtg gcccatgagg aagatggcaa
    44581 taaggacatc gtcaagcgcg tgattggaat gcctggcgac accattcgtt acgaaaatga
    44641 taaactctac atcaatgaca aagaaacgga cgagccttat ctagcagact atatcaaacg
    44701 cttcaaggat gacaaactcc aaagcaccta ctcaggcaag ggctttgaag gaaataaagg
    44761 aactttcttt agaagtatcg ctcaaaaagc ccaagccttc acagttgatg tcaactacaa
    44821 caccaacttt agctttactg ttccagaagg agaatacctt ctcctcggag atgaccgctt
    44881 ggtttcgagc gacagccgcc acgtaggtac cttcaaagca aaagatatca caggggaagc
    44941 taaattccgc ttctggccaa tcacccgtat cggaacattt taagagacct aagaggccga
    45001 gaatcaccaa tctcagcctc ttcttctatc gtgagaagtg attgtttatt gacaaatact
    45061 caacgaaaat caaagaacaa actaggaagc tagccgtagg ctgcttaaaa cagtgttttg
    45121 aggttgtgga tagaactgac gaagtcagct caaaatactg ttttgaggtt gcagatggaa
    45181 gctgacgtgg tttgaagata ttttcgaaga gtataaaata aaaacaatcc caactctcac
    45241 ctattcatgc aaaggaattt tatggaagtt tatttttcag gaaccattga acggattatt
    45301 tttgaaaatc ccagcaattt ttatcgcatc ctcctcctag aaatcgacga tacggacgca
    45361 gaggattttg atgattttga aatcattgtc acaggaacca tggctgatgt aattgagggc
    45421 gaagactata ctttttgggg gcaaattgtc cagcactcca agtatggaga acaactgcaa
    45481 atcagtcgtt atgatcgcgc aaaaccaact agtaagggct tggtcaagta cttttcaagt
    45541 agccatttca aggggattgg tctcaagaca gctcagaaaa tcgtggatac ctatggcgaa
    45601 aataccattg acgaaatttt gcaacaccca gaaaagttag aaggcatcgc aggactctct
    45661 gccaaaaatc gcgaggcttt cgtctccact ctccgtctca actacggaac ggagatggtt
    45721 ttgtccaaac tagccaacta cggcattccc aacaaactag cctttcagat tcaagacttt
    45781 tacaaggaag aaacccttga tgtggttgaa aattatccct accagctggt tgaggatatc
    45841 aagggtttgg gctttaccat tgctgaccaa ctagctgagg aactaggcat cgaaagtcag
    45901 gctcctgaac gcttccgcgc cggtctagtt cacagtcttt ttcaggcctg tatggaaaca
    45961 ggggacacct atgttgaagc acgggatttg ctggaacaaa cccttactct ccttgagtct
    46021 tcccgtcccg tggaactaga ccccagccaa gttgcccaag agctctccta cctgatcgaa
    46081 gaagacaagg ttcagcagat tgataccaag atctttgaca acagcctctt tttcgctgag
    46141 gaaggcatcc gcagtcactt ggttcgtatc cttgaaaaag gaaaacagaa gagtcatgat
    46201 ttagaaacca ttcaaaaaca tatcactact atcgaggaag agctgggaat tgagtatgat
    46261 aacattcaaa aacaggctat ctgtgatgct atccagaata aggtctttat cctgacaggt
    46321 gggcctggta ctggtaagac aactgttatc aatggaatca tcgctgttta tgccctgtta
    46381 gagggacttg acttcaggaa gaaaagcaat ctgcctattc ttcttgctgc tccaactggt
    46441 cgagctgctc gtcgcatgaa tgaattgaca ggtttgccta gcgcgaccat acatcgccac
    46501 ttgggaatga caggtgacga tgataccagt catctggaag attacctaga tgctgacttt
    46561 atcatcgtgg atgaattctc tatggtagat acttggctgg ccaatcaact cttctccaat
    46621 atctcttcta acagtaagat cctcatcgta ggtgacagtg atcagctacc ttctgtcagt
    46681 cctggacagg ttctagcgga tctgcttcat attcctttga ttcctcagac tcacttggaa
    46741 aaaatttatc gacaaagcaa agaatcaacc atcgtcaccc tagctagtca gattcgacag
    46801 ggcatcttgc cagctgattt cacccaaaaa aaagctgacc gttcctactt tgaaattgct
    46861 agtggccata ttcctgccac cattgaaaaa atcttaggtg ccgccctcag aaatggtatt
    46921 cctgcccgtg atatccaagt tctggctcct atgtaccgag ggacggcagg gattgatgct
    46981 atcaatcagc tcatgcaaga cctgctcaat cccccacaaa aagatcaact cagttttgaa
    47041 gctcctcagt gccactatcg taagggagac aaggtcattc atttggttaa cgatgctgaa
    47101 atcaatgtct ttaatgggga tttaggagct atcacagacc tgattcctgg taaatacacc
    47161 gaatcgaaac aagacgagat tgtcattgat tttgatggta atgaagtctc ttacccccgt
    47221 aacgaatggt acaagattcg cttggcctat gccatgagta ttcataagtc tcagggaagt
    47281 gagttcccag ttgtcatcct accgattact agtgctagcc gacgtatgct ggagcgaaat
    47341 ctcatctaca cagccattac acgtgccaaa agcaaactca tcttactagg cgaattacaa
    47401 gccttcgact atgctaccca acacatcgga actgcccgaa aaacctatct gattgaacgc
    47461 ttcagtgatc tactggagaa tgttgaagaa aagcaacaag ctgtctctga aacagtcaca
    47521 tcaagtgcct ctgaacaatc ctacatccta accgaagaaa actgggacag cattccagcc
    47581 atgattggga ttacagacac agacctcaaa gagatttttg gaaaatagtg catcagaaaa
    47641 accaccaatt caggtgggtt ttctgtttat taagattatt ttactgttgc tgtgcttgta
    47701 atcaattcaa cagctttttt gatagtgata tcatgtttca acatgtcagc tgaaagcaag
    47761 ttttgaactt gtgcaacttc catgttgtag tctgctgcca attgctcaac ttctttttgg
    47821 atttcttctt ctgaagcatc aaatccttca gctttggcaa ctgcttcgat aacaaggtta
    47881 gtcttagtac gtgactcagc ttctgcttgg tattggttgt gaaggtcttc ttgagtagtt
    47941 ccagtaattt ggaagtacat gtcagggttg atcccttgac gttgcaagtt cccaaggaat
    48001 tcatttactg aacggtgaac ttcttcgtgg atcatttctt ctggaagttc tacgatttca
    48061 gcattttcta cagctgtatc aattgctgca ccttcaactg catctttgta agcttcttct
    48121 ttagcagcag ccaattcttt gcggtatttt tctttcaagt cagcaagtgt ttcaacttct
    48181 tcatcaatgt cttttgcaag ttcatcgtca agagctggaa cttctttagc ttttacttcg
    48241 tggatagttg tcacgaattt agcttcttta cctgcaaggt cttctgcttg gtagtcttct
    48301 gggaatgtta cgataacatc aacggtttcg ccagctgagt gacctaccaa ttggtcttcg
    48361 aaaccaggga tgaattgacc tgaaccaagt ccaagtgaga agttttcacc ttttccaccg
    48421 tcaaattcaa caccgtcgat agaaccaacg aagtcgatca caacagtgtc gccgtcttca
    48481 gcagcagctt ccttgataac caattcagcc aggttgttgc gttcacgttc gatacgctct
    48541 tcgacatcag cgtcagttac ttctttttct acatcaactg atacttcaag gtttttgtag
    48601 tcacccaatt ttacttcagg ttttgtaaca acttcagcag cgataaccca gtcttgacct
    48661 ttttccattg aagttacgtc aatttttggt tgggcaacca cttcaagacc agcctctttt
    48721 acagctgctt cataagcgtt tggcaaaaga gcgttcataa cgtcttggta aagtgattct
    48781 tcaccaaatt ttttatcgaa gataggacgt ggaaggtgac ctttacggaa acctggaaca
    48841 ttaagagatt tcttcactga cttgaagaca cggtccaatt ctggtttgat ttggtcttga
    48901 gagatagtga aagtcaagac accacggttt gtttctttgt tttcaaatga tacagacatt
    48961 ctgtcatttc tccttaaaat tttttaaata cagtctatta taacattttc tataaataaa
    49021 atctagacta atgcagacaa ttatagacaa caagcctttt tcctaactaa aacactcata
    49081 aagtatagac aattttagac tactttggat atcttttggt tagtcatttt ccaaaactaa
    49141 tttatctaat ttttaagtta tatttgactt catcttctca gtaacatgag tataaacact
    49201 taaaatcttt gtttcattag tataatctac acgatccatt atcgctgtta taggtacttc
    49261 caattcagca agcaaactta tatgcgaata tctaaaaaca tgagcagtca atacaaaatc
    49321 atctttctta atttcacttt tcctaaacct gtttttcaaa aagtaattga aacaagttat
    49381 cattaaggga gaaccattat ttgtaaatat ataatcacct tcttctaaaa gaagatattc
    49441 ttttaaaatt tctaacactc tatcactaat accaattact ctatatgaag ctaaactttt
    49501 cggactatcc aaaaacactt cgttattgga cgattacatt atagtaaaac gaaataagaa
    49561 caggacaaat cgatcaggac agtcaaatca atttctaaca atgttttaga agtagaggtg
    49621 tactattata gtttcaatct actatacaag acgaaattga agaaatcttt ccattataaa
    49681 acgcatatta tcaaggtttt taaacaccta ataatatgcg ttttttccta ttttaaagac
    49741 ttttatccac ctattataca aagttaagta tccatcacag tttacaatta gccttcatta
    49801 cctaacccat tcaccatcct tcaagagagt aacctttaag aaccgaataa ataaatggca
    49861 aatttcgttc atttaattta actgcactgt taatttgatt agctccatct cctaaagtat
    49921 gcactcctac tacacggtga ctagcatcat aaactgtaga tccactagac ccctctaaag
    49981 tatcaacttg gtaatccaag aacatgccat catcacttaa aacttgtttt ttatctgtat
    50041 acatttgatg aactttaaaa ttatatgatg gatagcctgt gatagtcaca gttattcctg
    50101 tcaaattttt ttgactagta ggaagaccca aagtccctaa ttttgcacca atgggctctt
    50161 ctagaattaa taaagccaag tcatattccc ttgcatcctt agaatttaaa tttctaaatt
    50221 ccttcaaata acgaacttcc tttactttga tctttccaaa tggttcttga cttggactaa
    50281 cagtcggaag aacataaata tcatccgctt ctttcccata gtcatgtctg tagtagttgt
    50341 gagccgctgt aattaacaca ttatctttaa taaaattcgc acttcccctc ccttctacat
    50401 tcattccatc ggctactcca taatacttag ataaaaccat agctgaagtc gaatacggat
    50461 actgtaaagt attatcaatt ttaatcaaat catcattacc gataatactt ctgattgctt
    50521 ttggtagtat gaaccatatg ttggtgaaat ctcagataat gaagaatcat tagatcctgg
    50581 acctttttct agtgtctcac ttacctcata ttcttcaccc gtactagaaa taacactcaa
    50641 agcagatact gtcgataact ggctagccaa taaagtactc gcaataattg aaatacccaa
    50701 ttttttataa acagttttct tcattattgt atcctcctaa tgtaattata gcgtactatt
    50761 ctaaatttct taatctacta tagaatcaag aaatctacca ccttctttaa ataccctcca
    50821 ttatcacata aacaggtaaa cttttcaatt aatgactgcg cttttcaatc acgctagagg
    50881 tacttacttg cttctttgat actaagttca gccattcttt ccttgttttt ctcaataaag
    50941 catgttaccc aagtgggatt cgttttggag tagtctcgca gagtccagcc aatggcttta
    51001 ttgataaaaa attctgtttg gttcaagtta tgaagtagaa tcttttccat taattgagta
    51061 ttggtcttct cttttcttaa caactggtgg tcaatagcga cacgtctcag ccagatatta
    51121 tctgataggc tccattttat actcaatgaa aatcaaagag caaactagga agctatctgc
    51181 aacctcaaaa cactgttttg aggttgcaga tagagctgac gtggtttgaa gagattttcg
    51241 aagagtatta agattatttc ttctagttca gggtgttcat acaccaaact ccctactact
    51301 cgatctagga tatctaccgt gtcccaccag gattttgtca cgactaactg ctctagctta
    51361 ggcaaatcgg tttcctttag ataagactgc attgctttca aatagttagc agccacatat
    51421 tggtattttc taggctcctt ttcccagcaa gtgtctgcaa aatcccaatc gataatcttt
    51481 gtttttttcg cttctggtaa atatttttat agagtttatt tctttcaggc accgcaatac
    51541 ctagaaaaga aaattgatgg cgcatatagg cttccatggg ccttgctttt ttagagtctt
    51601 ttgctgcttc tagctcctca agtaaatctg ctaaactcat ctaaaactcc tcttgcccca
    51661 ccaaatggtg ctgaaaggca tagacagccg cctgggtacg atcgctgact tcaagtttgg
    51721 caagaatatt ggacacgtgg gtcttgaccg tcttgagaaa gataaagagg tcatctgcga
    51781 tgcgctgatt ttcgtagccc ttggcgatga gttggagaac atctcgctca cgcgcagtca
    51841 attcttcatg aagttccata tgattgcggt ggtattcaac cttcttgcta acctcttgct
    51901 caatggccag ctcgccagca gctaccttac tgacggcatg aagcaattca tctgcactag
    51961 aagtcttgag catatagcct ttggcaccag catctaagac tggcatgatt ttttcattgt
    52021 ccaaataaga ggtcacaatc aaaatcttgg cttcaggcca ttctttaagg attgctaagg
    52081 tcgcgtcaat cccattcatc tcaggcatga caatatccat gacaatgaca tctggacgca
    52141 gttccaaggc caagtcaatc ccttgagacc cgttggacgc ctcacccaca acttctacat
    52201 cgtcttggag gtcaaagtag cttttcaagc ccaaacggac catttcatgg tcatctacta
    52261 gtaaaatttt catctttact cctttatcat tccttatcta acaggggaat acggatatca
    52321 actgccagcc cttgcttggg agctgttaat aactgaaccg tccctgccat atcttcaacc
    52381 cgctccttga tatttcgcag tccataactc aagtcgtcta agcttcctaa ccggaaacca
    52441 atcccattgt ccaccacctt cagttgcaat tcaacatctg tctgatagag gtagacatct
    52501 aggcaagatg cctgggcatg gcggagggta ttgctaatca actcttgcag gatacggaag
    52561 atatgctcct cgattttctt aggcaatttc gtcatattct gcttgagact aaccctaaga
    52621 tcactcttgt cctcaagctc ttttaagaga atctgaatcc cttctatcaa gctcttctgc
    52681 tccagttcaa ctggtcgcaa atgcaagagc aaaacccgca aatccttctg ggcagtttct
    52741 aaaatagctg tgacactctg caactgggtc tgcatctttt ctctatccaa tttcaaagcc
    52801 tgctgactga tacccgataa aataatgtgg gccgcaaaca actcctgact gactgtatcg
    52861 tgcaaatccc gagcaattcg cttccgttcc ttctcgataa tttcctcttc ctgatcaagg
    52921 ctatgatttt cagctttttg aagagcctct gtcaaaaggt taagtttacc tgataaggac
    52981 ttgaaactgg catccaaatc tggatctaca acctgaacta cttcttgccc tgccaataaa
    53041 cgcttgagat tagcctgcat ttttcttaga gaaagctctt cgatccctcg ccaaaacagg
    53101 gctaagagac aggtcatgga catgctgaaa accaacaata aaaagacaaa tttttctgtt
    53161 ttttcgacat cgtacaaaaa gatagaccag tcaaaatcaa gtatttccag caagctgtgg
    53221 gagaaaaaaa agacaaatag gaaggaggtg agagcaataa tgacataggc ttgttttttc
    53281 atcctctaac cacctccaca tcaccaatca tagtggtcaa gaaaatcttg acactcttgt
    53341 tactcttgag atagtttttt gtttcttgat gatagtgttc attgcggagg gctcgcttgg
    53401 gctggttgaa aaaagtcaaa tccccataga gacagttaac gctgagactg acttccacat
    53461 ctacaggtac gatgattttg gtcgttccta ccatctttct gaggataatg acattgtcat
    53521 gattggttaa gatgaccctc tccagatgaa tagtgtcctt gcccatgaag cgaaagagat
    53581 tgatatcatc gaattggcaa gtctggtagc ttgaaaaatg atgaagattt ccaaaccaac
    53641 gatttttctc cttcttaacc gtcacaacct cttcaaaaac caaattggtc tgctcttttt
    53701 cctggttcat catcgggtaa agaagaaaga ggctatagat aaccgcaaca aaaatagcta
    53761 gaatcacaaa aggattgagc ataacgatga aaaagaagag aatggttacc gctactaaaa
    53821 gaagattatt tccctcttta ccagtgtagt agcgaatcaa aagcaaaaag aggaatagta
    53881 tcagcagaaa acgcgaaaaa tgctctgata ccatcaaaat cagagctcct gtcagaagac
    53941 aggcttcgat aaataaaaag attttaaatt ttctcatagg ttcatcctct cccttctatt
    54001 ttatcacaat tcaaaaaagt cacctcagtc tgaggatgga aaaaaaggcg ctggttacgc
    54061 ctttttcatc tgatcatttg cttcttttaa ttttccataa agaagatagt ctactttttg
    54121 tagatctgct atggtggcac agttaaggga acacataatc aagcgtagat ctgctttcca
    54181 gccttggaca atgccaagca cttcttcaac tgtgtaggtt tcaaccaatt ccagaacggt
    54241 tcgtgacaat cccacagcct tagcaccaaa aaccaagcac ttaatcatat ccagcggatt
    54301 ccgaacccct ccactaacca agagttcgac cttatctttc cattcttggg cattgagaag
    54361 ggcctgcatg gtagactgac cccattgatt gaggtaatca cgctggccac tacgacggtt
    54421 ttcgatatag gcaaagctgg tgccaccacg acccgatagg tccactgtac gaacaccgaa
    54481 ttcataggct ctttcgattg tcttggcatc cattccaaag cccacttcct tgaggacaat
    54541 aggaacggga atttgcttgc tataatctgc tagatgcgat tgccagcttc taaacttcct
    54601 ttctccctcg ggcatgagta attcctgcat gacattgaca tgcacttgca atagaacagg
    54661 attcatctct tctacagtat gaagtcctaa ctcgacaggc ttgtccaatc caatattggt
    54721 tccaaggagg agattgggat gactagactt gacagaaaaa gaatcatccg ttggattttt
    54781 gagggctgcg ctataagaac ccgttacaaa taaaatacca caggattccg ccacctgagc
    54841 cagcttttga ttgatttctc ttcccttatt acttccacca gtcatggcat tgatataaaa
    54901 aggaaagtcc cactttcgac cagcaaactc tgtcgaaaga tcgatttcat ccagattgta
    54961 aagaggcaag gaagaatgaa tcagctccac ctcatcaaag ctattatagg aacttttctg
    55021 ctcaagggca tagaggatat gctcgtcctt acgatttgtc gtcatgtcct atcctttctt
    55081 gatataagag ctcaatcccc agatcggccc aacgattttt taaggttttg gttgattgcg
    55141 catcaaaact cagggcgatg ccacagtcac caccaccagc accactactc ttggcaacgg
    55201 cctgcaaatc ttgactggct tctttcaact gtctaagcaa aggcgtgtaa atatctgtac
    55261 tcaagccttc taaaagcttg ctggctactt ctacttgctc gataactttt tcggctttcc
    55321 cctgctccaa ggcttcgacc aaagaaacca ccgtttcttt tgaggaactt aaaaaatttt
    55381 gattgatatt ttgcttgatt tgctggacca tgtgactcga tacagccact tccttggtcc
    55441 atcccactaa gaaatcacat tctaaagttg gtttcacttg tgagataaaa aatccccaat
    55501 cacgctccag aactgtcgcc aagttttctt cttctaacca agcagccgcc ttctggcgat
    55561 caaatgactg gtagagaacc aaatcctctg ccacaataca ggcaaggtcg cccatggaac
    55621 cattgtctcc tcgcttgagc aagacagcgc tagtcagctt gaacaagaga ttctgatcaa
    55681 ccgaaagatt atagagagcc agtaaagcct tgacaaccaa gacaacgacg ctgccactag
    55741 aacctagacc aaactttttc ccttctcgtt ccattttgcc acagattttt agggaaaaag
    55801 gtcttaaatt ctgaccgcga acagcgagga agtctcccat caaagcaatc gtttcttgaa
    55861 tcaagctgta gtcaggatta ggccttaagt ccactgcgaa atcaaacata tctgaataga
    55921 tacggtagct gtcagaaaaa gcaatctcag ctctcatata gatgggaata tcctttatca
    55981 aagctaactg ccctggctct aaaatagcat attcacctgc ccaatagagt tttccgcaag
    56041 ttttaacagc aatcatcttg actcaaatcc tttgtttttg acacaatcaa gcgataacga
    56101 tgaccgaaaa tttctgataa atgctccaag tctttctcct gacagaagac cttaacattg
    56161 ggaccagcat ccatggtaaa gtagcaggcc tctcctttct cacgaagctg gcgaacaaag
    56221 tccatagcct cataagaggc atccgtcaga taagaaaagg ctggactagc agtctttgtc
    56281 gtagcatgca tagccagggc atttttctcc gttaattctc caatcttggc aaaatcattt
    56341 tccttgagat aaatcagcat atcctgatag tccttctcag actgacgaac ccagtcgtcg
    56401 aaagtcgtcg aggtttccac acaaagtttc atcccgtcac ggctagagat tggttttttc
    56461 ttgtcctcta gcaccaacat aatcatagct agtttcaagt ctgtctctac agggtaaatt
    56521 tctccactat ccttatccca ggctcctagt ggtccataaa aactccgaga agaagagcct
    56581 gaggcaaact tggcttcctg cgctaactga cttctatcca atccaagctt gaaataagca
    56641 ttacaagcct tgaccagggc ggacaaacca ctagaacttg aggacaggcc cgctgccgta
    56701 ggcatattgt tttgagtatc gatacggaca aagccctcac cagctggacg ataacggtca
    56761 ataatcttac tcatcttggc atgctcgacc tcattttgta gctgaccatt gatgtaaaat
    56821 tcgtcagctg ttacattggc tggtaaaggc gacaaggtcg tctctgtata catattttcc
    56881 aaagttagag aaatactgct agtagcaggc accatctctt tttctttttt ctttccccaa
    56941 tatttaataa tagcaatatt tgcgtaggaa cgtactgtta caggctctct atccatgtct
    57001 gaacagctcc tttctcttct aatctttctg ctagttcttg tgcgtgtgtc aaattggtta
    57061 ccaaggctat gatacaacct cctagcccac caccgctcat cttggcaccc agagcaccat
    57121 ggctaagagt cgtttcaacc aaaaagtctg cctcagggct actgactcca atttctttta
    57181 aatgtaaatg cgcttgactg aggatttgtc ccagtccttc agcatctttt tgtgaaattg
    57241 caacttctgc ttgctgggtt aattctccca aggcatgcaa aaacggtagg gcatccttgc
    57301 ccttattttg aaccacttgg atggcttcac gagtatgacc ataaacaccc gtatcggcaa
    57361 tcaccaaata ggcggataaa tccatctcaa gttctgtaaa tcctacgttc ttgataaagc
    57421 gaataggttg gtcactgaga caggtcttag catccaaacc actaggattc atatgggcaa
    57481 tcatttcagc tcgattgacc aagatttcta gtacatcatg aggcagatca gcctgatagt
    57541 agtcaaatac cgcacgaatg gccgctatgc tgatagccgc tgacgaaccc atcccccgtt
    57601 tctcagggat agccgagtca atctcacaac gaatgcaggc ttctgtgata tccaaatact
    57661 ccagtgaggc ataaaccgcc atggacaagg tatcctcctc ataaaggcgc caaggactct
    57721 ctgcaggaac taccttacag gtcacctcca cctccaaaag aggcagggaa atggcaggat
    57781 aaccgtaaac gaccgcatgt tcccctatta aaattatctt actatgtgcc tgaccgacac
    57841 caactttttt tgtcattttt tccttttact agacgaaaaa acgtcttatt tttcatacaa
    57901 gtattaattc tttcctatct attttattat attttcacaa aaaaagcgat tgtttccatt
    57961 cacaatcgct tctttcatta ttgaacccat tcgccattat agttgacaga atagccatct
    58021 acggtcgtat tcactgccaa ggcacctgag ctataagcat agtaccattt gccattgacc
    58081 tggaaccaac ctgtcttcat gtctccatta cctgcattta ggtagtacca agttaaacca
    58141 tcttgatacc agccagttac catagctcct gatgaacgga ggtagtacca cttgttacca
    58201 aggtattgcc atcctgtttt catatcacca tttttattat ctaagtaata ccatttgcct
    58261 cgtacatatt tccaacctgt tgccatagaa ccagaggagc caaaataata ccattttccg
    58321 tttacttttt gccaatctgt aagcatctta cctgaagcat ctaggtagta ccatggagca
    58381 ggtttgcttc tatcaatgtc aatagtaaca tgaaaatctt gagtccaacc cttagcaact
    58441 tcaccaattg gtagtggatt gtaagaatca tcgccaaaat ttcctagctt atttaaataa
    58501 taccaattgc cgtcttcata aatccagcct gtctttacag cataattatt atcaaaataa
    58561 taagttctct tttcagcaga tagaggatat tgttcaccgt atacttttcc tgtattttca
    58621 gacgtttttg cctctagtac ttgtttatct gtttgttcta gcaaagcacc atcttgtcca
    58681 aaatagtacc acttctcctg aaggccaatc tcattaactg gttggttatc gaataaatta
    58741 tcacgataac ctgttccagg aatttctaag tattgccaac cgacaaccat ctctccaata
    58801 tcaccaaaat agtaagtttt accgtctatt ttatgccaat agattgcttt atgatcatct
    58861 tttacataat attttctatt atccttatca acaaatcggc cacctgtggt attcgcaaat
    58921 accgtatttg tagctagcaa accaaagaaa aagactgcta gtagaacttg catcattttt
    58981 ttcaaaagtt tcatctatat atcctcctaa aacgattgta gcaaagaccc gactgcatgt
    59041 caatatataa aaactcctca aaaaagcagt tacacaactg caactgctta tctattcttg
    59101 catggtatat ccaacaccac gcacggtttt aatgtagctt ttttggcctt taacatcaag
    59161 cttgctccgt agatagcgga tatagacatc tacgatattt gtctcggtcg cactttcata
    59221 cttccaaaca ctttccaaca attgctcacg agtcaatact ttcttgcttc ccataagtgt
    59281 cgccaaaagg tcatactcac ggcgggtcag agcaatcatc tcttcaccac gataaaccgt
    59341 gtgatgttca acatctatcc taagattgcg gtaggtcctt ggaactttca tcagactgca
    59401 gtgttgatca atgaagtccc gacctcggaa gatcgccgaa atacgcgcta ccagattttc
    59461 gataaggact ggcttataaa tgtatgaaac tgcaaaacgc tgaacaactt ccagctcttc
    59521 ttgcaagtct tcccaatgat ctaaaatcat gatgactgag gcaggtttag ttcgactcaa
    59581 tttttctgca aaatcctgag ccatcatatc tcccagatta acgttcaata acatcaaatc
    59641 atagtctgtc tgaagagcca tggagagggc tttttgcccc tcctctacca gatcaacccg
    59701 atactgctct ttctggagtt ccaaacttaa aaaatgagct agatttcgtt ctttctcaag
    59761 taataaaatc cgtttcccca tggctgacct acttattttt cgtcatacca agagtagtgg
    59821 aaggttcctt ctttgtcttt acgttggtaa gtgtgagcac caaagtagtc acgttgtgct
    59881 tggatcaagt tagctggaag gtcagctgaa cggtagctat caaagtaagt aatagctgct
    59941 gagaaagttg gcactggcac accagcttga accgcaagag ctacgatatc acgcactgct
    60001 tgttgatact tagcagtaac atccaagaag tactcgtcca aaagaaggtt ggcaagatct
    60061 gcatcgcggt tgtaagcatc tgtaatcttt tgcaaaaaac gagaacggat gatacagcca
    60121 tcacgccaga tagatgcgat atctgcaaat ggcaagttcc agttgttttc tttagaggct
    60181 acacgcaatt gagcaaatcc ttgtgcgtat gaaatgattt ttgagaagta aagggcttga
    60241 cggatctttt caatcaattc agccttgtct ccttcaaagt tgaaggcagc tggttttgga
    60301 agcaccttgc tagcatatac acgttcttct ttgtaagttg aaatgtagcg tgcaaacact
    60361 gactcagtaa tcagtgacaa tggtacacca aggtcaagag atgattggct agtccattta
    60421 ccagttccct tgttacctgc agcatcaagg atgtagtcta cgattggtcc atcttggcct
    60481 tcatcgtctt tacggctcaa gatatcagct gtgatttcga tcaagtagct atccaattca
    60541 cccttgttcc actcagtaaa gatttcagcc atatcctctg cagaaagacc tagcaagtgt
    60601 tgcatcaagt cataactttc tgcgatcaat tgcatatcac cgtactcgat accgttgtga
    60661 accattttca catagtgacc agctccatca ggaccgatat aagtcacaca tggtttgcca
    60721 tcttctggtg ctttagctga gatttcttca agaacatccg caaccaattc gtaggcctct
    60781 ttttgtccac caggcatgat agaaggacct tcaagagcac ctttttcacc accagaaact
    60841 ccagtaccga taaagttgat acctgagttt gccaattctt cattacgacg gatggtatct
    60901 ttgtagaaag tatttccacc gtcaatcaag atatcacctt tgtcaaggtg tggaagaagg
    60961 gcttggatag tagcatctgt accaggtcca gcttgaacca tcagcatgat acgacgaggt
    61021 ttttcgattg agtttacaaa actttcaacg tcatagcttg gtacaaaatt cttttcagga
    61081 tggcaagcaa tcacatcttc cgttttttct ttactacggt tgtagatagc aactgtgtaa
    61141 ccacgtgatt caatattaag ggcaaggtta cgacccatta cggccatacc tacgacacca
    61201 aagttagctt ttgtcatttg acactcctct tgtttcattt gttttatttt atcattttta
    61261 cttttgaaaa gaaagaattt tgtaacgact gcttagtagt ccaagtcatc cgcatgacca
    61321 gcgccatttc cgacaaagta gcctgtctta cagttaaggg taaagagata ggttccatct
    61381 ggcttataga ggttgtaata accattgccg ttaacgatat tgacacgttc aaggatatat
    61441 tggtctccag tgatatagcc acgtgaacgt gaagtcgcta gaatttgttc caagacacca
    61501 tccgcaaaat cccaggcaga gttattacta tcatcaatag cagactgatt ataggcaaca
    61561 cgactggcac ttctttgaac agcaacccct gcactcgaga gacccatatt gacttcactg
    61621 cgactacttc tagtctcatt tgaactactt ggttttggct cactagtcgt atttgaactt
    61681 gcttgacttg aacttgagct gctagtttga cttaaacttg agctagaagt acttgtttgc
    61741 tggctcttac caagactgat agccttatct agcactttat caagctccgt atttccagtt
    61801 ttaatatctg taaatttagc atccgatttg gctttggcat tggtatccaa cacaccatcc
    61861 acaatagctg atttttcaaa ttgtgcattg acatcttgaa tagccttgat ttgcgttgct
    61921 agactatcat atttagattt ggcaagcgta tgttcacgac taccttccag cttatcaagt
    61981 aaagtcttga gttgattcag tttatcaaac tggctatttt tcaaagccgt tttattgcta
    62041 tctgtgtaaa aggcgtcata aagtgtatta aaatcatcca catccgattg attggctgta
    62101 gttgattgag aagtttcaat ttccttggtc gaacgagcca cttgacggta gacataataa
    62161 gcactgacac aaataattac tgatacaagc gccaaaacgg tcaaaataaa gcctttttta
    62221 cttttctttt ctgagtcctc ttgatccaga cgagaaaggt tttgctcctc ttccacttct
    62281 tcagtcattt ctgttggatt ttcatcatct agcaatagag gatccaagcc ttgctcctca
    62341 tcgtccagag gcaagggtag taagatgtct tcagaagatg gaacttcctc cgaagaagct
    62401 tctgacttct ctacagcctc acgcatctct tgaattaaat catccagact ctgagtttca
    62461 acgaactcct cttttttgta ttgacgagtc gcaaacttat ccgcctcaat ttcatctctg
    62521 tgttgcttaa catacttgtc caaaatggaa tcctcaggca agactcctgc ttccacttct
    62581 tcatttttac gaatagcttg accaactgtt agctcttttg cttcatcaaa atcaaattgc
    62641 ggttcttgac cttctttttt ttgacgattt cgtctttttt tactcatgag tatcctttct
    62701 attttacctc ttgccgtttg acacgctgac caaaatattg atatagatcc actttcaagg
    62761 ttccgttgta taacttacgc ttcttatctg cttggctacc atacttgctt tcaaaagctt
    62821 catcactagt caggataaat ttgctccaag ttttcagcgg tgcaaatact tgccccatct
    62881 cagcatagag cttggtcacc cctgcatcat ctgacaaacg ttcaccataa ggcggattgg
    62941 aaatgattac tccattgatt ttatcggaac gtaaatcctg cacgcgcatc tgcttaaaag
    63001 taatgtctcc tgcaacacca gctacctgag cattggcctt agcaatttcc accatgcgag
    63061 catcaatatc acagcccatt atatccagct caagctcacg gtctactttt ttagccgctt
    63121 ctgtgcgcac ttcttgaatc aagcgatcgc tgatccagtt ccattcctca aatgcaaaag
    63181 agcgacgaag acctggcgcc atctttctag caatcataac tgcctcaata cagaaagtcc
    63241 ccgaaccaca ggtcggatca atcaaaggct tgtctggata ccagttagaa agttgtaaaa
    63301 tggctgctgc catattttcc ttgataggag cgccaccttt ttcggtacga taaccacgtt
    63361 taaagaggct agacccggtc gtatcaatca tgacagttgc cacatctttg agaatagaga
    63421 cctcaatctt aaactctggg ccattctcca tcagaggaac cccttctggg cgagcatagt
    63481 gtttctgcaa tttcttgaca acagctttct tagaaatagc ctgaacactg ggctcattgt
    63541 gaagtttgga cttaacacat ttagcttttg aaatcgggaa ccgagctcca agtggtaaat
    63601 aattttccca atccaaagcg aaaactccct gaaatagctc ttcaaaagtc ttagctggga
    63661 acgttcctac gataattttg atacgatctg ctgcccgaag ccaaaggttg gtttcgataa
    63721 tagctctcac gtctccttga aaacgaacac gtccattttc aacctgacaa tcgtagccca
    63781 actctcgcac ttcacgacca acgacagcct caagccctgc tgccacagtt gcaattaaat
    63841 taaattcttt tttcatgtta cagtcttgca agacctttct atatgtccac tttaaaaaat
    63901 gaggttgaga aaatttctca gccccaacct atatgcaatt ttctataagc catgttttgt
    63961 tccagaagtg actaggacca cttccttcga taatcatctg tctaccacta acagctctag
    64021 ctgatagcag tcagaatact acgttcgttt ccgcgtactc catgccccga ccaaaatttg
    64081 ggttgctagc ttgaggggtt taccgcgttc cactctctct gtttccagaa agactccgtc
    64141 actgtggcac tttcaagcct actctggcct atccaaggac ttagccattt caactgccgt
    64201 aacgatttct cgtccctagg cttatggttt cgcctagcac aaacactaca ggcatcacag
    64261 cctgtgctag catggacttt cctcatgaga agcaattctc ctcacgcgat tatccaaaaa
    64321 ttgcacatct caaataacta cttaaaaatc tgagttatct aaaatttgtt taccaaaaac
    64381 ttctttttcc aatctattca ggcgtttcaa aatatcaaaa ttcgtcatag aacttgtaat
    64441 tgccgcttca aggggttctg cttgaactgg tgaaggtttc ggtttacgag ttaattcttc
    64501 cttcaaatcc gcaatttcct gacgaagtga cttgaccaag gcagcatagg tttcatagtc
    64561 cttgatgaca tcgtctaaaa actcgtcaac ttctacttta ttatagccac ggacttcacg
    64621 tccaaactct tgttcaaaaa tatctttcgc tgaaaaaata atacttgcca tgtctctctc
    64681 cattctcgct tgctagtatt attatataaa aaaaggcaaa caaaaatcaa ggtcaaagct
    64741 tcaattttcg gaaaaatttt cagcaagttc atttaattga tcaaatgtta atctctttat
    64801 aaaatagtcc tcttgatttt tcatcttttg gtaaaaataa gctagttttg tttcattttc
    64861 ttcatcataa aaaagatagg aactagtcgt gttttccagc aaaaattgct gataatctct
    64921 taactgcccc ttgtgttcat aacgaggata agcatatttg acaaagtcta cctgcttaaa
    64981 gcgactcagt ttcatctgat tgccttcatt ccaattttcc ccatgggttt caaaagcaaa
    65041 aatggtggcc aactggaaac cgtattcggt tttcatctcc tgagcaacct ctaaaaccca
    65101 atattcaaaa cccaaacttc ctgtaaacac aagccaagac accccatctg ctgccatagc
    65161 ctctaaatct ttacgtatcg cttttttaat caatttaaga cgaggatcct tatcagaaaa
    65221 taaacccaaa tcaaaagcag aatagcctaa aaccaaagct gtagccattt ttaacccttt
    65281 ctgtgcaaat tatggtataa taaagtgatg ttattgtacc aataaggaga attatggtca
    65341 actatccaca taaagtttca tcacaaaaaa gacaaacatc tctttctcaa cccaaaaatt
    65401 tcgcaaatcg aggaatgtct tttgaaaaga tgatcaatgc taccaacgac tactatttgt
    65461 ctcagggctt ggctgttata cataagaaac caactcctat tcaaatcgta caagtggact
    65521 atccacaacg aagtcgtgcc aagattgttg aagcctattt tcgacaagct tcaacgacgg
    65581 actattctgg cgtttataat ggatattaca tcgactttga agtcaaggaa acaaaacaaa
    65641 aacgtgcgat tccgatgaaa aattttcatc cacatcagat tcagcatatg gaacaagtcc
    65701 ttgcccaaca aggaatctgc tttgtccttc ttcacttttc ttctcagcaa gaaacctact
    65761 tattgccggc attcgatttg attcgcttct atcatcaaga taagggacaa aaatcaatgc
    65821 cacttgaata tattcgagaa tatggatatg aaatcaaggc tggtgccttc cctcaaattc
    65881 cttatctcaa tgttatcaaa gaacatttat taggtggtaa aacaagatga acaaaccaac
    65941 gattctgcgc ctaatcaagt atctgagcat tagcttctta agcttggtta tcgcagccat
    66001 tgtcttaggc ggaggagttt ttttctacta cgttagcaag gctcctagcc tatccgagag
    66061 taaactagtt gcaacaactt ctagtaaaat ctacgacaat aaaaatcaac tcattgctga
    66121 cttgggttct gaacgccgcg tcaatgccca agctaatgat attcccacag atttggttaa
    66181 ggcaatcgtt tctatcgaag accatcgctt cttcgaccac agggggattg ataccatccg
    66241 tatcctagga gctttcttgc gcaatctgca aagcaattcc ctccaaggtg gatcaactct
    66301 cacccaacag ttgattaagt tgacttactt ttcaacttcg acttccgacc agactatttc
    66361 tcgtaaggct caggaagctt ggttagcgat tcagttagaa caaaaagcaa ccaagcaaga
    66421 aatcttgacc tactatataa ataaggtcta catgtctaat gggaactatg gaatgcagac
    66481 agcagctcaa aactactatg gtaaagacct caataattta agtttacctc agttagcctt
    66541 gctggctgga atgcctcagg caccaaacca atatgacccc tattcacatc cagaagcagc
    66601 ccaagaccgc cgaaacttgg tcttatctga aatgaaaaat caaggctaca tctctgctga
    66661 acagtatgag aaagcagtca atacaccaat tactgatgga ctacaaagtc tcaaatcagc
    66721 aagtaattac cctgcttaca tggataatta cctcaaggaa gtcatcaatc aagtggaaga
    66781 agaaacaggc tataacctgc tcacaactgg gatggatgtc tacacaaatg tagaccaaga
    66841 agctcaaaaa catctgtggg atatttacaa tacagacgaa tacgttgcct atccagacga
    66901 tgaattgcaa gtcgcttcta ccattgttga tgtttctaac ggtaaagtca ttgcccagct
    66961 aggagcacgc catcagtcaa gtaatgtttc tttcggaatt aaccaagcag tagaaacaaa
    67021 ccgcgactgg ggatcaacta tgaaaccgat cacagactat gctcctgcct tggagtacgg
    67081 tgtctacgat tcaactgctg ctatcgttca cgatgagccc tataactacc ctgggacaaa
    67141 tacccctgtt tataactggg ataggggcta ctttggcaac atcaccttgc aatacgccct
    67201 gcaacaatcg cgaaacgtcc cagccgtgga aactctaaac aaggtcggac tcaaccgcgc
    67261 caagactttc ctaaatggtc tcggaatcga ctacccaagt attcactact caaatgccat
    67321 ttcaagtaac acaaccgaat cagacaaaaa atatggagca agtagtgaaa agatggctgc
    67381 tgcttacgct gcctttgcaa atggtggaac ttactataaa ccaatgtata tccataaagt
    67441 cgtctttagt gatgggagtg aaaaagagtt ctctaatgtc ggaactcgtg ccatgaagga
    67501 aacgacagcc tatatgatga ccgacatgat gaaaacagtc ttgacttatg gaactggacg
    67561 aaatgcctat cttgcttggc tccctcaggc tggtaaaaca ggaacctcta actatacaga
    67621 cgaggaaatt gaaaaccaca tcaagacctc tcaatttgta gcacctgatg aactatttgc
    67681 tggctatacg cgtaaatatt caatggctgt atggacaggc tattctaacc gtctgacacc
    67741 acttgtaggc aatggcctta cggtcgctgc caaagtttac cgctctatga tgacctacct
    67801 gtctgaagga agcaatccag aggattggaa tataccagag gggctctaca gaaatggaga
    67861 attcgtattt aaaaatggtg ctcgttctac gtggaactca cctgctccac aacaaccccc
    67921 atcaactgaa agttcaagct catcatcaga tagttcaact tcacagtcta gctcaaccac
    67981 tccaagcaca aataatagta cgactaccaa tcctaacaat aatacgcaac aatcaaatac
    68041 aacccctgat caacaaaatc agaatcctca accagcacaa ccataacatt tatcacccag
    68101 atttttctgg gtgattttgt catagcacta ttgtatttat gtgcttaaca aaagcctgag
    68161 aagacatctt ctcaggcttt ttctgtacta taaacctcat tggaaaagat agagactgct
    68221 tccgtaatct tgttaagagg ttttactaaa tactagtctt tcttcgtttt tactacaaag
    68281 agagcagata gggctagact aacacttgct aggaagaggg ctgtgtcaga ttgactctca
    68341 cctgttgctg gcaagatttg ttcaggtgtt tctggtctag ctatttcttg cttataatct
    68401 ggcgtcttac cttgattgga aactaaagag ctaagtttaa actcaggttt ctctacagtt
    68461 ggagcatctg gtttcgtagc agaatctttt aattggttga gataatctgc aaagtattcc
    68521 accattcttt ccgtcaagag atggttatcc gtcgcatatt tcatgcttgc ctgaacgcta
    68581 gctacttcct cttgattgtc tttgtctgtt aatttctgag ctttagccaa agctgcttca
    68641 tagcctgaca agtcaagagg tgtttctgct acctgtggac gagtaaagat gagttccgct
    68701 gcagattggt atttatcgcc accatctccg taagtcttag tacctgtaag gacaattttc
    68761 ttagccttaa ttgtcttacc aaaatcaatg tcttttggct tattgttatc tggccaatca
    68821 gttgcagtaa aggtatgctc cttgccagac tcatctgtca caacaagttt cacatcacgc
    68881 aagttaccat ttgaacctga tccacgtgga acataacgaa gtccagtgat ttcagttggt
    68941 tctttcaaga ccatggttgc aggcttgcct acatctcctc cgccccatga tgtatgccat
    69001 aaactagata agtttccatc aaaggcattt gcaagacctt cttgagcctg agcaggagct
    69061 gtaagacttt caaagtcttc tgctaccaaa gccgttttct tctgaaccaa agcattcttc
    69121 aaggcttcaa tcttggcaat ctctgcacgc gcttcttcca cactgatatc atcatcggcc
    69181 tgactgaggt taaagaccgc ctctttcaaa gcatccatag actctttggt gtagttagtc
    69241 atggcaaccg ttggcaagta gttcttcaga gcattttctg tcaacatctt acctgttagg
    69301 gtaatttctt cgatttgaag attatccatc atgaagtcgt tataaccacg gaagttggca
    69361 tttccaccag aatcaccacg agtattactt gcatttccag ttgagtagat acctacccaa
    69421 gtatcccctg tttctgcacc tgtcacaagg aaggttgcct tcttggcttt cttagaatct
    69481 gtccaagtat ttggcaattc atgaatttcc aagttgcttg cttgagtgcc acgacgacct
    69541 gactggaatt ctcccttacc gactacaaaa gaataggtat tgtctgaacc tgcttcgtat
    69601 tcaaaggtta cacggtaggt cttacctgct tcaaaacgga agttttgcgg aatagtttgg
    69661 taaaccaagt tacgacggct cactagtcca tttgtcttga gtgaccaatt tccttcgata
    69721 acatcatcga cttttttacc attccaacca cgttgtgtat atggatcgtg tttttcagac
    69781 aagtgagtac ggttgtcttc gacaccttcg acaccaccca ctacaaatgg gaagataccc
    69841 tgagcaacat tttcaaagtc ttgcttgaag gtgcctttac ctgtatcatg cttgtctcca
    69901 tacatgcttg aattgttttc aaaggtacga atttcatcaa agtaagttgc ttgatcacca
    69961 gcttcacgac tcaatgtcag agtaacattt gagacgtccg atcctgttgt aaagaaggcg
    70021 tacatgtttt ggaagtaact tgtatcgtta actgtagcat tgttacgacg tgtattgtgg
    70081 gcgtaggctt ttacatagtt gagggcgaga gacttattgg tataagtagt cacttctttt
    70141 tcaccagtat tcacagtgat acttgccttg gcattactac ggttatctac accaacataa
    70201 acggcatact tggtatttgg tttcaagcca gttaatttct gagtgagact aactttttct
    70261 ttgtttcctt gaatacgaag catatcgttt gccccttgag acttgacaat ttctgcctta
    70321 gaagcatcgc ctgaaatggt ccaatgtttc aaggtaccgc tattaaatcc ttggtcatag
    70381 atgtgcatgc cttcactcca tgacatttca ggattagttt gtttcgaacg atagagaacg
    70441 tatggttgat ttgctagaag atctagggta attttaccat cttttacagt tagttcttgc
    70501 tcttctgtct taccttggtc agttagcttg taaaggtaaa ccttgctctt tgcccaatcg
    70561 cttggaaggg tccaagttgt tgcaccggcc tgcgtattga agtagtacat cttttcctta
    70621 tcagtagaaa gtttcttacc atttgcatcc cagttccaag gagtcaagta agctgaacca
    70681 tcttggatga cacgtccgtt gagcgttact gtacgttcac ggtatagtgg gctattgaca
    70741 tcatttgact tacgagttac aactaattta ttattgtcag catctaccaa ctccactcgc
    70801 atttctggag tccatttata agtgctaccg ttatcggtca tagtcaccgg tgtaccattt
    70861 tcccatttac ttacagtgaa gtgttggaag tacttggtca tgacgtcatg agcaaataag
    70921 ttggttacat agccattgta gtcacttctt ccttgccagc cttcaaagtc tttcatgctg
    70981 tagccaccta gcagtggata gttggctgca ccaccataac ttctgtagtc cccaacccaa
    71041 gcatcttttt ggtggttacg gataaagcgg gtgatggcac tgttgatacc tttattggtg
    71101 tagccaccgt aggtcaagtc agctgcccag tgatggaagg tagagtcgta ctcaccacca
    71161 tggccccact cgatcgcaaa gcgccagcct tgtttgttaa tttctttagc aagaacgtgg
    71221 gtagcccagg caccgttatc acctgattga ccattacccc aaacgtccac atagataaag
    71281 tcgagaccgt caccaagttt tttcttcaaa tcttcccaac gtgccaaacg actatgagct
    71341 aggtcatagg cagcatcaat gttgatacct tgatctagcc agttccaacc atagctatag
    71401 cttccatctg gattcttacg gagaattttt tcattgaagt atttagactc aggataagtt
    71461 tctgaagcgt taacgtggat acctagatga gctccatatt tcttagcctt ctcaattagg
    71521 gtcttgaagt cttcgacacc accgatacgc ttaccaatat cagcatagtt caagtgacca
    71581 gagtcatggc cttcgctacc atatccttta aggagaacac cttgcccaag accatctgtg
    71641 tggagattga ttttcttgat accatccaag gtcataagga atggattttg tgcttgagaa
    71701 ccaaagttca tcgcgatacg gtaagctgtg atatccttaa ctttttccca accttgagga
    71761 ttgttcataa tgctacgata agcaatggca ccatcttgcc aatcaacgtt cttgtctgca
    71821 ttggcatctt cagtgataac aaccttagca cttggaagtt ccttcgtgta ttctgggaaa
    71881 acaatgccct tataagcttt ttcccattgc cattcagagc tgtggattcc tacatagttg
    71941 gcatttccga ctgtttcttt ataagctgtc aaacgagtcc agtcattcga accaccacca
    72001 tagctatttt gagagttact ccaaacacca gcagcaagct tatctgtaga aacaaatcca
    72061 tacatgtaac ccttggctag gtctttcatt ggattggtta catcgatatg atcatctccg
    72121 ctgacatgcg tattgtttga catggttgcc ccatcaaact tagctccagt ttgatcacta
    72181 gaaacagaga ctaaagcatt gccgaggaaa ctaatagaag aaagtagttt tctttcgtca
    72241 tcaatctttt gacctggagt gacttgattg tggttgacaa tcttggtcac atcaaagtgc
    72301 aattgattgt ccacaacttg caagcgtact gtcatttccg cattgattaa gtgagcatca
    72361 tcgcgaagct tcatcaagta ctctgctgtt gtctcattga ttttcttata agtgacttca
    72421 ggggtgattc ggtggttatt gataaagact tggttgaact gttgcacctg tcctggcaaa
    72481 gtatgcccgt tcaagctgta ttccttgaca cgagggaagg cttggtcaat cactgctttg
    72541 aggaccttag actgaatcgt gtcataagtc accttgctat catcaacttc aggacctgtt
    72601 tctttttcag caggggtatc ctctgttttt accccctctt ggttatccgt tttaatgctg
    72661 acaaccgtac gctcatcgtc ataagagccc gccttgagaa ggatcttctt ctcattttta
    72721 agatggtcat tgaccgcagc tggtagagtc actgtgtcaa agagattgac atcgttgttg
    72781 ctggcattta gctgaccgtc tgacttgaga gtgatagaga gacggtttgt tgatcctgtt
    72841 tcaggagcag caacacgact acctctatac caagtgctag ctgttggaga tttatactcc
    72901 cagaaccagc catccttgtc ataaccgaca aaaacattat tattggtatc tttaaatttc
    72961 aagaagacac caaagcgtga tttgcccttt tcagaatcat ctttgaaggt taaatcaaca
    73021 gttgcatttc cattggcatc aacggtcaag cccttctttt caaacagagc tggtttacct
    73081 gcgttatcat tttgagcagt tgaggatagt tggttgtagc ggacaccttt ttcttctcgg
    73141 atagtgactg ttccctgttg ttcttttttc tctaccgttt gccattcagg ggttaccgtc
    73201 ttaggtgttt caggtttagc agctgcaggt ttatcctctt ttggtttttc ttcagccggt
    73261 ttttcttttt caagtgctaa tagttcttct tctgtcttag gtccatctgt aacttctgga
    73321 gaaccttggt cttctcccac cttaggcgct tcaaaatcac gcccatcatt ctcttttgct
    73381 gttgcaagag cagtagctaa atcagctggt aagttcgccg tggaaccaga ctgcacgcta
    73441 tctgcaagaa ccggacttgt cccaaagaat gcagctccaa tcataacaga agcaacacct
    73501 aatgaaaatt tccgaatact atatttacaa cgtttttcaa ataatccttt attcataaac
    73561 ttctaaatcc tttcattttt gagcaagcgt ttacattttc tttttaaaaa atactccttc
    73621 ctctgaaagt gcaatgctta accctga
//
LOCUS       DBERDS010000006        64246 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.006, whole genome shotgun sequence.
ACCESSION   DBERDS010000006 DBERDS010000000
VERSION     DBERDS010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 64246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.006"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..916)
                     /gene="pavB"
                     /locus_tag="ACL73E_000443"
     CDS             complement(<1..916)
                     /gene="pavB"
                     /locus_tag="ACL73E_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGS0800476.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
     gene            complement(1032..1442)
                     /locus_tag="ACL73E_000444"
     CDS             complement(1032..1442)
                     /locus_tag="ACL73E_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGS0800477.1"
                     /translation="MYYLPVDFYRYLIGREGQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            complement(1509..1682)
                     /locus_tag="ACL73E_000445"
     CDS             complement(1509..1682)
                     /locus_tag="ACL73E_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGS0800478.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGWDQVGNFSKGQYIMMHS
                     LIYRTDLLRASQF"
     gene            complement(1992..2657)
                     /locus_tag="ACL73E_000446"
     CDS             complement(1992..2657)
                     /locus_tag="ACL73E_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGS0800479.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(2671..4050)
                     /locus_tag="ACL73E_000447"
     CDS             complement(2671..4050)
                     /locus_tag="ACL73E_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS0800480.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            complement(4663..5427)
                     /locus_tag="ACL73E_000448"
     CDS             complement(4663..5427)
                     /locus_tag="ACL73E_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGS0800481.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(5644..6201)
                     /locus_tag="ACL73E_000449"
     CDS             complement(5644..6201)
                     /locus_tag="ACL73E_000449"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HGS0800482.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLHPLDPQERNSGIEYGKPITIGDNFWTGGGVIVLPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            complement(6307..7161)
                     /locus_tag="ACL73E_000450"
     CDS             complement(6307..7161)
                     /locus_tag="ACL73E_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0800483.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            complement(7517..13087)
                     /gene="zmpC"
                     /locus_tag="ACL73E_000451"
     CDS             complement(7517..13087)
                     /gene="zmpC"
                     /locus_tag="ACL73E_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpC"
                     /protein_id="HGS0800484.1"
                     /translation="MSRKSIGEKRHSFSMRKLSVGLVSVTVSSFFLMSQGIQSVSADN
                     MESPIHYKYMTEGKLTDEEKSLLVEALPQLAEESDDTYYLVYRSQQFLPNTGFNPTVG
                     TFLFTAGLSLLVLLVSKRENGKKRLVHFLLLTSMGVQLLPASAFGLTSQILSAYNSQL
                     SIGVGEHLPEPLKIEGYQYIGYIKTKKQDNTELSRTVDGKYSAQRDSQPNSTKTSDVV
                     HSADLEWNQGQGKVSLQGEASGDDGLSEKSSIAADNLSSNDSFASQVEQNPDHKGESV
                     VRPTVPEQGNPVSATTVQSAEEEVLATTNDRPEYKLPLETKGTQEPGHEGEAAVREDL
                     PVYTKPLETKGTQGPGHEGEAAVREEEPAYTEPLATKGTQEPGHEGKATVREETLEYT
                     EPVATKGTQEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKI
                     ERQGQAGTRTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLT
                     KVENKKSITVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPY
                     TVKTHLTYNLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSE
                     APTDTAKYFVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTF
                     TVAKSKAEQPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTG
                     SLIGSDGTKSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANIN
                     NVAVEGKISGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNS
                     SRVNKVRVDALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIV
                     GSTWQNGRVNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQI
                     DAKVADYGITVTLDDTGQDLKRNLREVDYTRLNKAEAERKVAYSNIEKLMPFYNKDLV
                     VHYGNKVATTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVT
                     FKENFINSQVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGA
                     ANDAALDNLYLDRQFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAF
                     MLGLTYMNRWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIVALGNSGLDNLRASNT
                     VGLYANKLASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVRE
                     KQESPTADRKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERY
                     RDSVDGVILSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGF
                     NVKDETGRTYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDA
                     YGTSVYTHEMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKA
                     EKDDLNRLHTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFR
                     KIENYYVRDTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKR
                     NGYYTISMFSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAF
                     ASGSKTFSSWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITI
                     QYELGNPNSTKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNA
                     YLRTTDDFRNSIYK"
     gene            complement(13539..14752)
                     /locus_tag="ACL73E_000452"
                     /pseudo
     CDS             complement(13539..14752)
                     /locus_tag="ACL73E_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
     gene            complement(14869..15906)
                     /locus_tag="ACL73E_000453"
     CDS             complement(14869..15906)
                     /locus_tag="ACL73E_000453"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGS0800485.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            complement(16022..17188)
                     /locus_tag="ACL73E_000454"
     CDS             complement(16022..17188)
                     /locus_tag="ACL73E_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGS0800486.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            complement(17533..17937)
                     /locus_tag="ACL73E_000455"
     CDS             complement(17533..17937)
                     /locus_tag="ACL73E_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0800487.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            complement(17944..18759)
                     /locus_tag="ACL73E_000456"
     CDS             complement(17944..18759)
                     /locus_tag="ACL73E_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0800488.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            complement(18746..19651)
                     /locus_tag="ACL73E_000457"
     CDS             complement(18746..19651)
                     /locus_tag="ACL73E_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS0800489.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            complement(19679..20155)
                     /locus_tag="ACL73E_000458"
     CDS             complement(19679..20155)
                     /locus_tag="ACL73E_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0800490.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            complement(20152..21939)
                     /locus_tag="ACL73E_000459"
     CDS             complement(20152..21939)
                     /locus_tag="ACL73E_000459"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGS0800491.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            22287..23003
                     /locus_tag="ACL73E_000460"
     CDS             22287..23003
                     /locus_tag="ACL73E_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0800492.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            23318..27256
                     /gene="strH"
                     /locus_tag="ACL73E_000461"
     CDS             23318..27256
                     /gene="strH"
                     /locus_tag="ACL73E_000461"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGS0800493.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(27311..28609)
                     /gene="purB"
                     /locus_tag="ACL73E_000462"
     CDS             complement(27311..28609)
                     /gene="purB"
                     /locus_tag="ACL73E_000462"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGS0800494.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(28672..28899)
                     /locus_tag="ACL73E_000463"
     CDS             complement(28672..28899)
                     /locus_tag="ACL73E_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS0800495.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVKAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            complement(28909..30000)
                     /gene="purK"
                     /locus_tag="ACL73E_000464"
     CDS             complement(28909..30000)
                     /gene="purK"
                     /locus_tag="ACL73E_000464"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGS0800496.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            complement(29987..30475)
                     /gene="purE"
                     /locus_tag="ACL73E_000465"
     CDS             complement(29987..30475)
                     /gene="purE"
                     /locus_tag="ACL73E_000465"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGS0800497.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            complement(30505..30621)
                     /locus_tag="ACL73E_000466"
     CDS             complement(30505..30621)
                     /locus_tag="ACL73E_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGS0800498.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            complement(30878..32140)
                     /gene="purD"
                     /locus_tag="ACL73E_000467"
     CDS             complement(30878..32140)
                     /gene="purD"
                     /locus_tag="ACL73E_000467"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGS0800499.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            complement(32262..33809)
                     /gene="purH"
                     /locus_tag="ACL73E_000468"
     CDS             complement(32262..33809)
                     /gene="purH"
                     /locus_tag="ACL73E_000468"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGS0800500.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDMTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELSAN
                     GETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADNIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            complement(33834..34343)
                     /locus_tag="ACL73E_000469"
     CDS             complement(33834..34343)
                     /locus_tag="ACL73E_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS0800501.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(34427..34972)
                     /gene="purN"
                     /locus_tag="ACL73E_000470"
     CDS             complement(34427..34972)
                     /gene="purN"
                     /locus_tag="ACL73E_000470"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGS0800502.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            complement(34969..35991)
                     /gene="purM"
                     /locus_tag="ACL73E_000471"
     CDS             complement(34969..35991)
                     /gene="purM"
                     /locus_tag="ACL73E_000471"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGS0800503.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(36028..37470)
                     /gene="purF"
                     /locus_tag="ACL73E_000472"
     CDS             complement(36028..37470)
                     /gene="purF"
                     /locus_tag="ACL73E_000472"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGS0800504.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGKLKRHRDMGLLSEVFRNPANLDKLTGTGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEDRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSMTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(37563..41288)
                     /locus_tag="ACL73E_000473"
     CDS             complement(37563..41288)
                     /locus_tag="ACL73E_000473"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGS0800505.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNVGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGLSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVAIVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELETALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEVANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(41345..42052)
                     /gene="purC"
                     /locus_tag="ACL73E_000474"
     CDS             complement(41345..42052)
                     /gene="purC"
                     /locus_tag="ACL73E_000474"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGS0800506.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            complement(42222..43571)
                     /gene="comB"
                     /locus_tag="ACL73E_000475"
     CDS             complement(42222..43571)
                     /gene="comB"
                     /locus_tag="ACL73E_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGS0800507.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKEDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLINQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(43584..45737)
                     /gene="comA"
                     /locus_tag="ACL73E_000476"
     CDS             complement(43584..45737)
                     /gene="comA"
                     /locus_tag="ACL73E_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGS0800508.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(46324..46449)
                     /locus_tag="ACL73E_000477"
     CDS             complement(46324..46449)
                     /locus_tag="ACL73E_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS0800509.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(46452..46682)
                     /gene="blpU"
                     /locus_tag="ACL73E_000478"
                     /pseudo
     CDS             complement(46452..46682)
                     /gene="blpU"
                     /locus_tag="ACL73E_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            complement(46885..47176)
                     /locus_tag="ACL73E_000479"
                     /pseudo
     CDS             complement(46885..47176)
                     /locus_tag="ACL73E_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(47222..47455)
                     /locus_tag="ACL73E_000480"
     CDS             complement(47222..47455)
                     /locus_tag="ACL73E_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGS0800510.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(47461..48453)
                     /gene="plsX"
                     /locus_tag="ACL73E_000481"
     CDS             complement(47461..48453)
                     /gene="plsX"
                     /locus_tag="ACL73E_000481"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGS0800511.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            complement(48450..49220)
                     /gene="recO"
                     /locus_tag="ACL73E_000482"
     CDS             complement(48450..49220)
                     /gene="recO"
                     /locus_tag="ACL73E_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGS0800512.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(49217..50386)
                     /locus_tag="ACL73E_000483"
     CDS             complement(49217..50386)
                     /locus_tag="ACL73E_000483"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0800513.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTSQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            50535..51545
                     /locus_tag="ACL73E_000484"
     CDS             50535..51545
                     /locus_tag="ACL73E_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGS0800514.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(51728..52165)
                     /locus_tag="ACL73E_000485"
     CDS             complement(51728..52165)
                     /locus_tag="ACL73E_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGS0800515.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(52250..54883)
                     /gene="polA"
                     /locus_tag="ACL73E_000486"
     CDS             complement(52250..54883)
                     /gene="polA"
                     /locus_tag="ACL73E_000486"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGS0800516.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            55139..56046
                     /locus_tag="ACL73E_000487"
                     /pseudo
     CDS             55139..56046
                     /locus_tag="ACL73E_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            56172..56453
                     /locus_tag="ACL73E_000488"
                     /pseudo
     CDS             56172..56453
                     /locus_tag="ACL73E_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(56587..57555)
                     /locus_tag="ACL73E_000489"
     CDS             complement(56587..57555)
                     /locus_tag="ACL73E_000489"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS0800517.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(57700..58514)
                     /locus_tag="ACL73E_000490"
                     /pseudo
     CDS             complement(57700..58514)
                     /locus_tag="ACL73E_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(58539..59036)
                     /locus_tag="ACL73E_000491"
     CDS             complement(58539..59036)
                     /locus_tag="ACL73E_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGS0800518.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(59109..60470)
                     /gene="radA"
                     /locus_tag="ACL73E_000492"
     CDS             complement(59109..60470)
                     /gene="radA"
                     /locus_tag="ACL73E_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGS0800519.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLQQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(60484..60999)
                     /locus_tag="ACL73E_000493"
     CDS             complement(60484..60999)
                     /locus_tag="ACL73E_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0800520.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(61001..61444)
                     /locus_tag="ACL73E_000494"
     CDS             complement(61001..61444)
                     /locus_tag="ACL73E_000494"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGS0800521.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            complement(61504..61597)
                     /gene="ffs"
                     /locus_tag="ACL73E_000495"
     ncRNA           complement(61504..61597)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL73E_000495"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(61630..62097)
                     /gene="tadA"
                     /locus_tag="ACL73E_000496"
     CDS             complement(61630..62097)
                     /gene="tadA"
                     /locus_tag="ACL73E_000496"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGS0800522.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(62298..63584)
                     /locus_tag="ACL73E_000497"
     CDS             complement(62298..63584)
                     /locus_tag="ACL73E_000497"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGS0800523.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(63815..64051)
                     /gene="comW"
                     /locus_tag="ACL73E_000498"
     CDS             complement(63815..64051)
                     /gene="comW"
                     /locus_tag="ACL73E_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGS0800524.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT        18893 a        15092 c        11840 g        18421 t
ORIGIN      
        1 taacagcttt ttcgacagtt tctttagcaa ctaatccatt gatgttgatg tctacatttt
       61 tagtagcaac tagattagtc aagtcagctt taccgtcttt atttccgtaa actttaacag
      121 tagctttata agtttgagta ccattagcgc gaagttgatc aattaaagct tgaccttgtt
      181 taccaacagt attgccattt aagtctactt catagaagta tttccctttt gttaatcctt
      241 caagaggagg taaagcagga tttttagcag taccattgtc agaccaagga gcattatccg
      301 aagcttttag taatagacga gttaacatac catcaccagc gaatagttca taagggatta
      361 cttggtttac accggcagtg aaaggacctt tcccttcagc tttttcaaga taagcagcag
      421 gaacatcgat gctgtctttt gtattttctt tcactccacc ttttacttgt tcaggagtag
      481 tttctgctgg acttgcttgt gtcccatcca catcagctgt atctacagtt tcttttaaga
      541 catctgttag ctctggattt ttttgagctt cttcatcttt ttcaaaaagt gtatccagac
      601 tagaagagtt tgtttcctcg ctcacttcag ttctttctgt aggtgtcgga agtgaattcg
      661 tatttccagt aacgccctca ggtttcgctt gagtgagaac ggtgtctcct ggtttttctg
      721 ataagtcacc ctctttcgtt cccgatgtct cttcaggtaa gacttgacct ggggtcggat
      781 tgaccacatc ggcacgtaca gaacttggct gaccaactag gacaaagaag ccactagcca
      841 caacaactga ggcaacaccg acactgagac ggcgaataga ccaacgagta tatctttgat
      901 ttggattgaa tttcatagga ttctccttag agtctttctt tatttgatga ctctagtata
      961 atctcctgaa attaaaaagg actaagaaaa agttaaaatt tttcttaaat ccctcttata
     1021 aaacacttat attaattaaa tccataaaca gatttggtga tttgatagac gacattggac
     1081 agtttgcgat ctggcaagac agaatgtttg gtcaaacggc tcaacatggt cttacgaata
     1141 gcctgaaaga cttctggatt tttctgctga atataggtcc acaattggcg tttttttgcc
     1201 agatgctccg ctgtttcaga tcggttgagc agggtactgg aaatcaccgt cgtgatttca
     1261 atatgattca gcagatattc tcgcattttg ggatgactca cttgggacaa atcaagctgg
     1321 tctaccaaga gtcgattgac cttgagttgc tggtcaatgc acttaatcat cacttgctca
     1381 ttgacagact ggccctcacg cccaatcaaa taacgataga aatcgacagg cagatagtac
     1441 atggtcttga cctgctgaag gggcgtaaag acaaagagat tatcgacata aaaagtatgt
     1501 tcaggcaatt agaactggct agcacgcaac aaatctgtcc gataaatcag cgagtgcatc
     1561 atgatatact ggcctttgga gaaatttccg acctggtccc agccaatcac tagcgactcc
     1621 acacagtaat gaagataggc tgctgcatta tagctagaaa tggcgataga caataacttc
     1681 ataatctgct cctttagggg actgattttt tcttatactc ttcgaaaatc tcttcaaacc
     1741 gcgtcaacat cgccttgccg tatagatgtt actgacttcg tcagttctat ccacaacctc
     1801 aaaacagtgt tttaagcagc ccgtagctag tttcctagtt tgatctttga ttttcattga
     1861 gtattactct ctcttgtcac ttccttctat tttaccataa agtccagcct ttgaagaact
     1921 tttactagaa gacaaggggc ttctgtctct atttgccatc ttgggcatca aaaaagaggg
     1981 gtcatccctc tttacgaatt caatgctact agggtatcca aatactggtt gttgatgact
     2041 gccaaaatat aggtatctgc tttcaagagg tcatctggtc caaattcaac atccaatggg
     2101 gaattttcct gctctcggaa acccaaaata ttcagattgt atttgccacg gaggtctaat
     2161 ttactcagac tttgacctgc ccaagactga ggaattttca tctccacgat agacacattt
     2221 ttatccaact gaaagacatc aacactatta tggaaaagaa tggtctgtgc tagagactgc
     2281 cccatttcat actctggcga gataaccgag tcagctccaa tcttttctag cactttctta
     2341 gcggtctgac ttttgacctt agcaataaca gtcggtaccc ccaaactctt acagtgcata
     2401 accgcaagca cactcgactc cagattttca cctgtcgcga ctacaacggt atcgcaggta
     2461 tcaatccctg ctgatctcaa taattcttca tctgtgatgt caccaatcac tccacgcgcc
     2521 aaaactggct caaactgatt gatgcgctct gcgtggtcat caatagcgat aatattcata
     2581 tcctgcttgg ctagggcagc taggacactg ctcccaaaaa ttcccaagcc caaaattcca
     2641 atcgtacgat ctgacatgct ctttcctttc ttaaccaata ctaatatctg ctttcatata
     2701 gtgaatcata tctttctttt ctggatggta atctgccaag ctaacaaaca aggtcaaggg
     2761 accaattcgt cccataaaca taagtggcat gataacactg agagccaatt tcccaaggtc
     2821 aggagtcaga tttgccgtta caccaactgt actaagagct gaaatggttt caaatatgag
     2881 gtggataaag ggaggattgc ctttggctgt tatccctagc agaatcaatc ctattaagaa
     2941 gctcatcaaa aagataataa agacactaaa ggatttttga accgttcgcg gcgcaatcgt
     3001 tcgtctcgca acattggcat gaggcaagcc tagaagctca cttcgtgcaa agaccaagag
     3061 gacaaaaaat gtcgtaatct tgagtccccc agctgttcct ccaggtgccc cacctagaaa
     3121 catctgtaag atataaatca aaagagtcac aggatgagcc tgagtataat ctatcgtaga
     3181 aaagccagct gttcgcatcg tcactgtttg aaaaaagcta actaaaacct tatcggcaac
     3241 agggagattg ccaatcgttc cagcattgtt ccactcaaga aagagagtag ttgccgttcc
     3301 aaataacaac aaacctatag tcaacaatag tacaagcttc gtatgaaagt gcagacgtcc
     3361 ttttttcttt cttcctacat gaccagccaa atcaaaccag accataaaac caaggccgcc
     3421 tgtaataatt aagcctgcaa tcaccagatt gaccagtaaa tcggtctgaa aagcaaataa
     3481 actggtgctc cctaaattat caaaaccggc attacagaag gctgagatcg ctagaaaaat
     3541 ggaactaaaa agaccacgtc cccagccaag ttgaggaata aggcgaaaac taagcaaaat
     3601 agctcccaag ctctcaacca aaaaggtcgt gagaaaaata gaatagacaa actttctcaa
     3661 agatcgagtt tctccataac taaaactatc ctgaatagtt gcacggctac gaagactaag
     3721 cttttgcttg ctctggatat agaaaacccc aataaaggtc atgagcccta gaccaccgat
     3781 ctgaatcaag agcaaacaga ttatttgacc ccagatatta taggtgtgag ctactggaag
     3841 ggttgagaga cccgtcacac agactgcaga tacagcagtg aaaagatgat caaaataagt
     3901 cgctcgtgag ctttcaactt ggacaaaggg caagctcaaa agaagagagc ctagtaaaat
     3961 gaccaaggca aaactcaaaa aaatacgacg ggctggcgat aaacgagata agcctagctc
     4021 tattttttcc ttagataatt tgaataacat gtttccattg taccataaaa agttcgaaat
     4081 gacttagata ggataaggca aaatctacta acaccaagcc taaaaaatgc caccttttta
     4141 ttgatagctt aggcaagaac aatacttgat agatgtgact ataggtcaaa aaagcaagac
     4201 aggagctttt aacgccagct actctatatg cttttcagga gaaaatttct ctttttgatt
     4261 ataggcaatg aaaaccaagg catcgattag aaagctagtc acaggttgct caaaacactg
     4321 ttttgaggtt gcaaatagaa ctgacgaagt cagctcaaaa caccgttttg aggttgccgg
     4381 ataagactga cgaagtcagt aacatatacc tacggcaagg tgaagctgac ctggtttgaa
     4441 gagattttcg aagagtatca tttcatctca ctctaaatct tatcgacata aaacgcatag
     4501 tgtcaaagtt ttcatcacct gatatgatac gtttttctga ttttaaagat ttttcccaac
     4561 ctcaacatgc ctaggacaag aggaaggtga cctcgtttaa acatattttt gaaaagtatg
     4621 agctagacat tttatgataa aacaaatcct ttgccagtac aactaaaggt ggtgaacact
     4681 tgctaaactc agttctagcg ccttattaaa agcttccgag ccccagtcac gactgtcgta
     4741 ctggtccaag tccgctagag aatctgctgt gaacaacaat tcaccccaga gaaccccacg
     4801 caattgagct actgccgcaa gagcggaaca ctccatctcc acaacagcac agtcttcttc
     4861 cttgcgataa gccacctttt cagccgtttc tcggtaaaaa ccatctgtgg accaggtcat
     4921 gacttcttca taaggaatcc ctctatcatc caaaactcgc tcaatggcag caatagcctc
     4981 tggctgcatt tccatataac gagaaggtgc cacatagtgg taactggctc cttcatctcg
     5041 cagagcgcga acagggacta gaaaggcatt ttcctctata tcagctagga caccacaggt
     5101 cccagtagag ataatctgct ccacaccata gccaatcaac caatccataa actgggctgc
     5161 tggagctgaa ccgacaggag cctgaaccag acaaatctcc tcgtccttgt agttcacgac
     5221 ataaactgga taggtcttgg tggcagaaac aaattcgcca acacagttcg cccctacttc
     5281 cctcgcatag cggtcaatct cctcacctaa aaatgcataa acacacttct ttggcaactg
     5341 caagtccagc ccctcgtgat tgggcatgat aaccgcctga ggattgtcat caaactctaa
     5401 aataggaatc gcatgtttct gaatcatagc ctgcctcctc taattttgta ctattgtatc
     5461 aaaatctgac cgagtgtcaa ggaggaagct gatgaactga ggagaaaaac atcccactta
     5521 cgagatgctt tgaacttgct taatgaaaca gacttgctaa gagatagagt aggtaaatgt
     5581 gaactgggta aaaaatgatg aaacctacaa aaaagaaaca accccagctg ttccttttta
     5641 cttctattta acaggtattt ccttaatcac gcgcgcagga ttgccagcta ggacaacgtt
     5701 gtcgccaaaa gatttggtaa ttactgcccc tgctcctgca acgacattat ttcccagtgt
     5761 cactccagga aggacaatga cgccaccacc agtccagaaa ttatctccga ttgtgatagg
     5821 ctttccgtac tcgatacctg aattgcgttc ctgtggatct agtggatgga ggggtgtcaa
     5881 aaactgacaa ttaggaccaa tcatagcatt gtccccgata cgaatgggac agatatccag
     5941 catggtcaag ttccaattag aataaaaatt ttcccctaga tggatgttga caccgtagtc
     6001 caccatcaag cgagtgttga tgtaaagatt tttcccggtt gaggcaaacc aagtcttgat
     6061 gatttcggct cccttcaagg ggttctcttc cttgttaaag gcggcctgtt tttggcgaga
     6121 agcctgagct aaggctctca gttctgggtc tgatggacgg taaaactctc ctgctatcat
     6181 tttctggtat tcgctagtca tattattctt ctccttattc cctactatca tatcaaattt
     6241 tccacgtatc tgactagaat aaggagcact ttctacaatt gatgctctac cttcatcaca
     6301 taccatctat ctagctaaac gaatacgggt cacgatgcca tctgagtctg tgatttccaa
     6361 ttggatcgat gtcatccatt tgattggtgc gtcaacttct tgtgctcgtt gggcaatcgt
     6421 taacagttct tctttatgtg cgacttcgat gacatagtag gctaaacctg gtaggacttg
     6481 tttacgcgga tccagacctt ttcctcccca ttcgttgact gctaaatgat gatggtagtc
     6541 cccagctgcg atccaactag cactaggcac actgaattta tcctcgagcc ctaacaccgt
     6601 ttgataaaac tgtctggact ttcgactatc cttgacagaa agatgaatat gccccattct
     6661 cgtaccctct gctaggataa aaggctctac tctttccccc aactcataga tatcctgagc
     6721 cgcaaggact tcagtcaccc cgataatacg tccatcttct cgaatatccc atgtggaaac
     6781 tggcttatct cgatagagtt caatgccatt tccctccaag tcctctaagt aaagggcctc
     6841 actgtaaccg tgatctgcac cgccaacaag aggaatctgt aaatccgtca ggtgcttcaa
     6901 gacatccgcc aaagcctttc gtgtcggcaa aagaatagcc agatggtaaa gaccataatg
     6961 ttcccttact tctccaccct cttgtgcttg aatcaagtgt accaaggctt ttcctccaag
     7021 tcccagaacg acctctgtat ccgtttgaga taggatttct aaaccaataa tctgctgata
     7081 aaaaactgtt tgactgacca aatccttcac atttaaaact gcctctgcta aataaatgtg
     7141 gctctggtat tcatatgtca taaatatttc ctcttttatt gtaactttaa ttattacaac
     7201 tattatataa cttccctcaa gaaagtcaag ccagacaact tgaagcatcc cactcagcaa
     7261 aaaacaatcc cagaaaaaat cttctaggat tgttttgtat ttattttact agactagcaa
     7321 agttatttct caaatcaaca ttttctgtgg gattgaaatc caccttgtca ccattggtcg
     7381 ttgatgagtt gaagatgatt cctgcaatct gcattcaatc aaatctctac atcgatccat
     7441 aagaaaaagg agtcgatttg tcatctgact cctcatcctt acaagaaaca ctactcaaca
     7501 atgaaactct acaatcttat ttatatatag aatttctaaa gtcatctgta gtgcgaagat
     7561 atgcattata gattttttgt tttaataaat gcacccaact tgctggggta tgactcgttg
     7621 cacgatctat attagtaata tctttcgcag ccgcttcatt aattaattgt tgcatttgtg
     7681 cagccgttgt tatagttact tcttttgtac tattaggatt acctaattcg tattgaattg
     7741 ttattggttt cagattatct tgtttatcta tacgttgttt aaacattgct tttttgaaat
     7801 cagcccatga tgagtactca ccattgaata ctttcttaaa tactaaatca tctgtcacta
     7861 aagcaacatc tcttccatgc catgatgaga atgttttgct tccgctggca aatgcttctg
     7921 ctccgtactg attagaaaca taaggtagga atcctttgtg ataacctttt tccgcaagta
     7981 attcataagc tatttttcta aacataatat ctccaggagc acctttcgaa ttgcttagcg
     8041 ctgcgtatac aggagagaac atacttatag tatagtagcc atttcgttta tattctctat
     8101 tatcatcata gctacgtcta tttatgatgt cgttgtcgat taatgagttt aacgatgtta
     8161 agttagctac ttcttcatct gttaatggac ggactttatt tcctgcatgt gtatctttat
     8221 tatgtctagt atcacgaacg taataatttt ctatttttct aaaccatttt ttcttaacat
     8281 cattattttg agctaatatc gcttttgctt ccatcgcatc aagtgtatac attacatcat
     8341 atgatccatg catataactt tgaagcgcct catccgaatc gaaacgttcc accggattat
     8401 atgtatgcaa tctattcaaa tcatcttttt ctgctttata taacgtattt aaagctaaaa
     8461 tatgagaatt tacactatct acagattgca gtaaaccaag tgcgtataac tccgctccca
     8521 atccttcacg tctaccattt ccttcaaagt agattgcaga atcagaatta tgaaccattt
     8581 catgagtata aaccgacgtt ccataagcat ctaataatct atctaacaca aagtgcgtta
     8641 aacttccatt cgcatacgct cctgcactac tattatactc ataccatttc ccaacaggtc
     8701 cgaagaattc tttaatagag ccgatgtttt tatccgttaa ccttgcccaa taagttcttc
     8761 ctgtctcatc ttttacattg aatccatcat aaactatcac agaacggaaa agtttttctt
     8821 ttgaagcact gtcaagaaga ttgtaccaaa tatcataatg gtctctatgc cttttcgctg
     8881 ctatatcaac tctatttctt acataagttc gtaaagcatc tcctgaaaga ataactccat
     8941 ccacactatc acgatatctt tcatacgaac cgaatgcaag tgtagacata ttcgatgaaa
     9001 tatacacaga ttcttcaggt aaagttagta gtggtaataa catactctta tgcccccaac
     9061 ttggtgctga tattctatcg taaactccta atgaatattt tctatcggct gttggtgatt
     9121 cttgtttttc tcgtacttct gcaatatcag acttcatttc gactatatat gcctttgtat
     9181 tttctttaaa ccactcgtta tttgttttgt ttggtaagaa cagttttcta tacgcttcta
     9241 cgaagtcaaa gactgaatct tctcctttta ccgatgcaag tttattcgca tataaaccta
     9301 cagtatttga agctctcagg ttatctagtc cactatttcc taatgcgaca atagtatcca
     9361 acgttgaagt ctcattattt ccgttaaagt caaacttgta cgtagataaa tcttttgtat
     9421 tcattttacc ataattaata tcgtaccaac ggttcatata agtaagacct agcataaatg
     9481 cttctttgtt atttttgatt ttctcactta cgtattcaac tacaccgtct cctgtagtat
     9541 tgattgattt atccatcgct aatacttttc ttaggtgttc tgctatatta gctttaactt
     9601 cttcaaattg tctatctaag tataggttat ctaaggctgc atcattcgct gctcctagta
     9661 cttttttagt agcttctgag ttaagtgtta cattttgcaa gtcgcttagt acgttattcg
     9721 ttatcgctgt atagtctgaa acaaatgctt ctggtgtgaa tatatattct tttcctgtaa
     9781 cattgtattc gattacttga ctgtttatga agttttcttt gaatgttaca tctaggtatt
     9841 ctactgtatt atctttgaaa tgtaacataa ctttatttat tgaatttttc ttattattaa
     9901 tatccgttac tacttcatca tctttcatcg gcacaacatc taacaattct gtagtgtaaa
     9961 gtttatctgt tgtcgctact ttgttaccat agtgaactac taggtcttta ttgtagaatg
    10021 gcatcagttt ttctatgttg ctataagcta cttttctttc agcttctgct ttatttagtc
    10081 ttgtataatc aacttctctt agattacgtt ttaaatcttg cccagtatca tcaagagtta
    10141 ctgtgattcc ataatcagca actttcgcgt ctatttggtc ttttgataat tttgtagcga
    10201 atctgtctgc ttttctatta tcaactgatg tacttgcatt tttcacatct gctgctgcgt
    10261 attgatcacc ggtgataaca taaccatctc caacatctac gttactcaca acattattta
    10321 ctcgaccgtt ttgccacgta gatcctacta ttcctccgac tctagaatat ccttgaccat
    10381 ttcgtatttc tccagtagca accgaattag atatcaatgc accattttct aatctaccta
    10441 ctatccctcc agctgtttgg ttattattgc gtgcattagt agagattaag gcatctaccc
    10501 taactttatt aactctcgaa ctatttcctg ttatattacc tactattcct ccagtatcat
    10561 ttttattact gtcctggtga tttgcgataa gtttccctgt aaacgagctg ttttctatca
    10621 ctgtatttgt tgcgctcgct actaatcccg caacagattt cgcacctgag atttttcctt
    10681 ctactgcaac attattaata ttcgcgctat tcgctgcctt cgccagcgct gcgacatttt
    10741 ctttactatc agcagaaaca gttttaatat ccaaatctct aactgtagca ccatttaatg
    10801 tatcaaataa tggttttttc aaatcataaa tggcatacga ttttgttcca tcagaaccga
    10861 tcaagctccc tgtaaatgca cctgtgagat aacttgtctg cttatcgcct aagctcacct
    10921 catctgcggt catatctgaa gccaatgtat agacaccaga cagattgctt tgcatggctg
    10981 ttaccagctg tttaaaggat gtgtaaactc ctggttgctc tgctttagat ttagctacag
    11041 taaatgtgta atcatctttg taaccgtctg taccttcttc gacaagttga tcaacggcta
    11101 ccgtcacttt atacgttcca tccgtatttt ctgtaataga ttttacaggt aggtacattt
    11161 ctttgaagcg atctgatttc acttttacaa agtatttagc cgtatcagtc ggcgcttcac
    11221 ttagacttaa atatctacga taacgatcat tttctttacc gtataattct actgaatcaa
    11281 tatctttaat ctctattttc ttatactcta attggaaatc ttgagttgat gtttcagtat
    11341 tttcctcatt attttcaccc aaattataag ttaggtgtgt tttaactgta tacggtgtgt
    11401 agtaatctaa acctgatatt acttgctctt tggcaggatt ttctatatcc acctctttaa
    11461 ctagcttgtc tccatggaaa acttgcgttt ttgcagaaac atatgctgag gtagtgtcta
    11521 ttaagttata acttacagtt atagattttt tgttctcaac ttttgttaag tttgtaattt
    11581 ctactgtagg tttaactttc acaagtgttc ctactttaac gacttcgttg accggagcta
    11641 cttcagttcg tgacacttct ttagtttcta cgacattacc atttacgatg tagtcttcat
    11701 attgaattgt acgtgtccct gcttgccctt gtcgttcaat cttacgacga tttttcagaa
    11761 gtgttggatc ctgaatttct tctgttgtat aaggaatatt ctggatttcc gttctatttc
    11821 gtgtagtgac ctctaaagcc ggaagttctt cttctactgc cgcttcgccc tcatgttcgg
    11881 gttcttgtgt gccttttgtc gctaccggtt ccgtgtactc tagagtctct tcgcggactg
    11941 tagctttgcc ctcatgacct ggctcttgcg tgcctttcgt tgctaacggt tctgtgtaag
    12001 ctggttcttc ctcgcgaact gcagcttcac cttcatgtcc gggtccttgt gtacctttgg
    12061 tttctagtgg cttagtgtag actggtaagt cttcacggac tgcggcttca ccctcatgac
    12121 cgggttcttg cgtgcctttg gtttccaatg gaagtttata ctctggtcga tcatttgtcg
    12181 tcgccaatac ttcctcttcc gcactctgca ccgttgtagc agacacagga tttccttgtt
    12241 ctggcactgt tggtcgaact acagattctc ctttgtgatc cggattctgc tcaacttgac
    12301 ttgcgaatga atcattagaa gatagattgt ctgctgctat agaagatttt tctgaaagtc
    12361 catcatcccc tgatgcttca ccttgtaaac taaccttccc ctgtccttgg ttccattcta
    12421 aatcagctga atgaactaca tctgatgttt ttgtagagtt tggttgacta tctctttgag
    12481 cagagtattt cccatcaact gtccttgaaa gctctgtatt atcctgtttc ttagttttga
    12541 tataaccaat atattgataa ccttcgattt tcagaggctc tggtaaatgt tccccgactc
    12601 cgatagaaag ctgactatta taggcagata aaatctggct ggtcaaccca aaagcactgg
    12661 ccggcaacaa ttgaactccc atgctagtca acagcagaaa atgaacaagt cgtttctttc
    12721 cattttccct tttagaaacc aataaaacta acaagctcaa tcctgcagta aaaaggaaag
    12781 taccaacagt tgggttaaaa cctgtattcg gtaaaaactg ttgagatcta taaaccaagt
    12841 aataagtatc atctgattct tcagccagtt gtggaagggc ctctaccagc aaggattttt
    12901 cctcgtctgt caatttaccc tcggtcatat acttataatg aattggactt tccatattat
    12961 cggccgatac cgattgaatc ccttgactca tcaaaaagaa actagataca gtaactgata
    13021 ccaatcccac tgacaacttt ctcatcgaga aactatggcg tttctcacca atgctttttc
    13081 ggctcatatt aacctcgctt tttctatatt ctttatatca atctatattt tatagcataa
    13141 aagtataaac ataaaaataa tatagtatgg aattttctga gtacttttca acaattactt
    13201 atcattatac aataaatcga tagaaatttc tattgaaata tacttaaaaa tattctgcat
    13261 actataaaaa atacagtaaa ttataacgat aaaaaacaga gataacatct caacaagtaa
    13321 gtgtggactt cagactaatt acagcatttt ttaaattaga ttaccgctta tgcttttaat
    13381 gggctataaa atattagctt acaatagaaa agtctgaaat tgaggcgaca agaatccaat
    13441 ctttataaat caaaagaggc caatgttcgc catcaacctc tttcttatcg ttcattcttt
    13501 ttgctaagta agatgaatgc tttacctatg gcctgagcct agtttaccca ttcaccatta
    13561 ccatttacac ggtaaccatc tggtgttgtt gtgctcacag ccaaagctcc tgaaccgtag
    13621 gcatagtacc agtgtggtcc gactttaaac caacctgtct tcatgatacc tgcttcgtca
    13681 aggtaatacc aagtgccatt ttccttgtac cagcctgtct tcatagctcc tgagccgtca
    13741 aagtagaacc atctgctacc atctgttccc cagcctgtaa acatagcacc tgaattgctc
    13801 aagtaatacc agctaccaga aaattttaca aatccagtct gcatgacacc taagtcattc
    13861 aaatagtacc atttaccatc tgttttcacc caacctgtct tcacatcacc agactcatag
    13921 aaataccatt taccattaga ttccacccaa ccagactgat cagacgtaga cgctctaaaa
    13981 tctttcagtg gtttttctac aaccgtagct ttagttttaa ctgttgaaag gtttgaggca
    14041 gtcacttctg tacactgaac agcagaacca tatctaccag ccaattcctc tgaagaagca
    14101 tcatcaccta gagtttgagc aattgtaata gctttgtatt gattgttagg atttttaaaa
    14161 gctgccatcc ccatgtgtgt aaatttaggg ttaattagcg actcatagtg accagatttc
    14221 ccgttgtctg aaccactatt tttttctcca cataatctgc tttttcagca cgccattgtt
    14281 caatagcttt tagaaaaccg tcatgattcc atgccaaatt ttctcccatt atactattag
    14341 aagttggaaa ggcactccaa agatctttgc tagaaagacg ggtatgatcc atggttatag
    14401 atgcttctgt agctctggca aaagctgcct tttctaggtc agttgaccat ttgataggga
    14461 catacttatc taccaaacct tcgtcagccg cttctttaca gatagcattg atggcatcca
    14521 aaatagattg ttgatgagga gccacaaatt ctcctttgat tccaaccaaa acattgccac
    14581 tagaaggttt tagcacctct gaggtcaata cattttcatt tttaccatca gtagtttgtg
    14641 ttgccacaag tctgtcgttc gcaaaaacat catttgtcaa aactgctcca gccaaggtca
    14701 aagccaaggc actagcaaat acaattttct tcgtttcttt cttactcctt attgtagttt
    14761 gaatattata ttaacagata gctttcaacg cttagttata tcatattttc ctactatttg
    14821 tctctgcgta cctattccta gctcccaaaa gtaggcgcaa tgactctttt acttcacaac
    14881 aagttcataa cgtgtcttac tggtgaaggt ttgaccagct ttaagaatga cttggccttt
    14941 aaggtcactg tgaatggcat ctggtaaagc ttgcgcttca agagcaatcc cattgtgctg
    15001 tagcattggc tgacctccta tgatgacact ttcatccaca aagtttgctg tgtagaccac
    15061 aaagcaagga gcttctgtct tgaaaagcag gaagcgacct gaattttggt cataaaggaa
    15121 tccagcattg tcatggcctg caggaagggc aaatggatga tccaaacctg atgccagctg
    15181 gatttgctca tcttcttctg caaagatatc cttcaacaag gtaccattgt agacgtgttt
    15241 gaccacatca cggttggctt ctggagtttt ggcaggaaca ccgtcaggag cgattgagta
    15301 aatgccctct gtgtttagtt ggaagacatg acggtcaatc gtctgcgtga aatcaccaga
    15361 caagttgaaa tagctgtggt tggttggatt gaccagcgta tcctgatcgg tcgttacctt
    15421 gtagctgatt tcataggcac cagtttcttc caagtgataa ctgatccaaa tcttgagatt
    15481 tccagggaac cctcctgtcc catctgtacg ctctgtgtag agagtcaagc catgatcgct
    15541 tacttcttca acttcaaaca agctggaatc ccaaccagtt gaaccactgt gattacagtt
    15601 gctagcatta ttaacctcaa ggtcataggt cttaccattg agctcaaagg tcgcacctgc
    15661 aatacgaccc gctacaggac ctacacttgc tccatgcttg ggactattgc ctacataact
    15721 atcaaagtca tcaaatccca agataacatt ggcaaaattt ccagccttgt caggtgcgac
    15781 atagcgcaag atagtcgcac cataagtcat aacctcaagt tggtagccac cgtctgtctc
    15841 aaatcgatag gccaagacat cctcaccctc aacatttcca aatacacgct ctgtgtatgc
    15901 tttcattctg ttctcctttt actatttctc tcaagcaaac aaaccataga aagcgtactg
    15961 acaatctatg gtttatctga taatttacaa atcctcttgt caagaattca taaacactgt
    16021 cttacttttg atattcgtga attatgacac cttgtactac acggtttact gtacctgtag
    16081 gagacggtgt atctggttta ttttctacct tgagtgaagt caataaagca aagagttggg
    16141 cataaacgat gtaagggaag acacggtaaa tatcattcaa gacaccgcca caaccaaggg
    16201 ccacttcttt gacattttca agaccaaaag cttgatcact caaaagcaca acacgacgag
    16261 caatctggtc accagcaact tcacgaacca agtccaagtc gtacttacga gtgtagtctg
    16321 tcgttgtacc aaagaccaaa acaactgtat tgtcgttgat aagagatttt ggaccgtgac
    16381 ggaagccaac tgggctttca tacatggtcg caacttgacc agcagttaat tccaaaatct
    16441 tgagctgagc ttcatgagca agtccaaaga aaggaccagc gcctagatag atgacacggt
    16501 taaagtctaa atcaacgagc tctttgacat cttctgcctt gtctaaaact ttacgggcaa
    16561 gactagatac aacttcaaaa cgttcagact taacagcaaa ttctgtagga tcaaagacca
    16621 agagagttgt caacatcata gacgtaaagc tagaagtcat ggcaaatcca gcatcattag
    16681 agacagctgg ttgcaagagc aagagattac gatcatcacc gtgagcttga agagccaatt
    16741 taccatctgc tgcacaagta atcgtcactt gataaagctc atccaccaag gatttggcca
    16801 aatcaacagt cgccaaactt tcaggcgaat tcccactacg agcaaaagac acaaggacag
    16861 ttgccacatc ttttttcaaa taggttgctg gattggcaac gatatctgtt gtcgcaatag
    16921 cattgaaatt ccatttgcgt tcgtcataga cttccttaaa ataaggtagc aaggtatctc
    16981 ccacataagc agaagtccca gcacctgtca agataacctt aatatagtca tgtttatcag
    17041 cgatttcttg taggaaggct gcaatttctt cacgttttgc ttgataaaat tcaaaagctt
    17101 ctctccatac atcaggctgt tggtagattt cacgcgtagt gatttctgca cccaattcga
    17161 gcaagtcttc ttttgtataa tgtagcattg agttcctctt tttctattaa atatgggaat
    17221 gggagtaagc tacattccca tgtatattct atataaaatg ctctaacgat tttcacgttg
    17281 tcacatgaat tgaatcgagt tccaactaaa atctgtagga aactagccgc aggctgctca
    17341 aagcactgct ttgaggttgc cggataagac tgacgaagtc agctcaaaac accgttttga
    17401 ggttgccgga taagactgac gaagtcagct caaaacaccg ttttgaggtt gccggataag
    17461 actgacgaag tcagtaacat atacctacgg caaggcgacg ttgacgtagt ttgaagagat
    17521 tttcgaagag tattattcat cttcgtcatc atcgaagccc gctaacaggt cattaacttt
    17581 cacaatgctt tctgcagcac ggctcttgta gtccgcatct gcgcctgtaa ggctcgcatt
    17641 gataaattca atcaccattg gaagattcat ccctgcgtaa aggtcaatat cacgaccttc
    17701 catgatcaag cgactcacca cattacaagg tgtcccaccg agaagatccg caaagactag
    17761 gaaatcatcc aatccttcaa taacagcttc aaatttagca gtaaattctt ctgggccatc
    17821 ttctggaaga agagctactg tgtaaatgtt gtcttgtggg cccataatca tttctgtgct
    17881 acctctaagc tcctcacaga agcgaccatg gctcaccaaa attaatgatt tagtcataag
    17941 gaattacatt ccaagtgcaa agtgaccaag ggcagaaaga gccaaagcaa gtacgataat
    18001 aataccgata gctttagtag agttcatacc tttcttacca agcaaccaga agataaaggc
    18061 agtaaagatt gctggaagca aacgtgggaa gatttggttc aagatgtctt ggaaatcaat
    18121 catcttttca ccgattggca acttgtaaga aatttcaaag ttaatcactg ttgctacaag
    18181 agcacccatc atgaagacac caagtacaga tgcagcgtca atcaaagctg tcaaggtact
    18241 ttgcatgttg ttgataaggt taaccccttc tttgtaagca aattccaact gtttccaacg
    18301 gaagatgtca tacgctactg caactgcaat ccaaaggaag atcccccaag gttggccagc
    18361 gatagccata gttgctgcga ctgaccccat gatagcaggt acaagtgaac caaagattgt
    18421 atccccaaga ggagcgaatg gtcccatcaa acctgtcttg ataccgttaa cggcgtcttt
    18481 tgaacctaca ccatcttttt cttccatggc aaggtcaaaa ccagcgataa tggtatggaa
    18541 gaatggtgaa gtattgaaga attgagtatg aactttcatc atttctttca attcaggagt
    18601 tccatcacca tacattttac gcaactgagg caagatcatg taaaggtaac cagaagcttg
    18661 catacgttcg tagttccaac ctaattggaa agtaaacaag ctacgtttgt tgatttgatt
    18721 aaaatcttct tttgtaagtt tgtaattaga attcgtcatc ttcgatttcc ccactttctg
    18781 atggtgtaga aggtgctgct acagctactt tttggctatt tttgaagtga agcactgcaa
    18841 ggaaaatacc tacgatagaa ataccaatca tagacaaacc tttgaagttg ttcacgaaac
    18901 caattttttc agcaacttca gcaggaagag tacctacgat accagcaaca gcgccaccaa
    18961 gacctgttac atatgagtaa agaacagtca acatagctgt caaaccaaat cccatagcaa
    19021 ggtagtgaag gttacgttta actggaaggt aacgaagcaa gattgcaaat ccaagacctg
    19081 gaagcatacg tcctgcaagt gtcaagccat ctgcaaccca tttgtaggct tcaacgaagt
    19141 ctactactga ttgtacaaag gcaccaccaa aagcaagggc aaagaagact ggaagggcac
    19201 gagatagagc ccacggaatc gcaccaagca agtagttgcg ttcaatacct ttatagtcaa
    19261 agcgttcgat tgcagcatcc acacggtgag cgaagaaggt agtagtcata cgaccaagaa
    19321 cgtcgaagta agtcaagaga gctgctactg gtacagcgat tgtagtaatg gcaagcggtg
    19381 catcaattcc ttgtgaaaca gagaaggctg tcgcaagaac cgcaccagaa gttgcgtcga
    19441 tacgagaagc accaccgaag gtaccaaccc caagaacgaa cagttgcaag ttaccaccga
    19501 taagtaaacc agtagtcaca tctcccatga ttaaaccagt aatgaaacca gcaaatacag
    19561 gggaacctgc agatgaaacg atcgtcaact catcacagat ttgataagct gagtacaaag
    19621 tgagaagtaa aatttgccac cattgtatca taacaatgac ctcctaaaaa tttttttcct
    19681 attttaataa gctcaaaaag tctgaaattg gatcatttgg aaccatctga gcagtaagtt
    19741 taacaccttt ttctgccagt ttgtggaagt cttccacatc cttgtctact acgttgatag
    19801 aacgtgtaat agaacgagtt tctggtgttt gagacatatt cccaacatta agggtttcaa
    19861 gtggtacacc tgcttctacc aaaccaagga agcggtctgg tttacgagcc acgataaaga
    19921 gacgttggct atcgtatttg ccagcaagaa tattggctgc agctttctca actggcaaaa
    19981 tactcaattt cacacctggt ggtgtcgcaa gtttcaaacc actcttttca atatcgttgt
    20041 tgacaacttc gtcgtctaca accataatgc gtgaaacatt tagttttcca gcccaaagat
    20101 tggctacttg tccgtggatc aaacgtccat caatacggca tcctacaatt gtcataagtt
    20161 ttcccccttt atatgtttta gtgtaggttt acgagttaaa tgaatctctt ctttatattg
    20221 accttctgtt tcaaagataa tgatgcggtt ggcaccttcc ttgagatagc tatgagggat
    20281 ataaagtgag agagttgggc caacgttcca aaaacgtcct agattctgcc cattgacaaa
    20341 ggcaaccccc ttaccaaact cagacaagtc taggtaagta tcttttggct cttcgactgt
    20401 aaagtcataa gcgtaaaagg ctggttgtcc ttgagtccat ccttttgaaa aatcaatttt
    20461 ctcaggattg tctagtggga gtggatagtg tttccagttt agtaagaaat gcagatcctt
    20521 acagacccct gtccgaattc ccttacgttg cgtatccgct aagaacttat gcccatagtt
    20581 gacacgcccc atattttcta tcaagatatc taacctagat agccctttct ttttaccttg
    20641 ataaaaaata tcttccccaa tctctgtctg atattgagtt ttaacccact gaccatcgac
    20701 atacagctgg gccctatctc gaccatcaat gatacgaagt ctttcttctt ctgcatccca
    20761 gtttgtttct gttcgataaa gtaggtagcc ataactttgt cccagctcct ccatcttttg
    20821 aggatagaga ctttctacag gacttgacaa gctatctaag gtttcaaaca aagaaacttt
    20881 ttcaactagt ggaatagcat ccaactccat actctctttg tagagtggtt ccaactgcgg
    20941 atactctgaa aaatgtgttg ccatcatctt cttgactgca agatatttag cagttggatt
    21001 tccttcttca tccagaaggg catcgtaatc ataagacgta acttgtggca ggtccaaagt
    21061 tcctcgagct gagcaaccat tcatgaaacc aaagtttgta ccaccgtgga acatgtaaag
    21121 attgatagag ccttgttcca aaacctctcg aactgcatct gccaattcct taggatcccg
    21181 tgtgataatc ggttctttcc agcgattgaa ccaaccatcc cagaactcca tacacatgag
    21241 tggccatttc ttaccatgtt catcaaagaa ttcctgcatc tgcgaaaagt tgtaaggtgc
    21301 cttagaacca aagtttcctg ttacaaagag gtcctcttca attaaggttc cagctttcag
    21361 agtagctcgc catggaccat ctgatgtaaa gaggggacag gttacgccac actcttccat
    21421 tagctgtcga atcgctctca ggtaagcctt atcttctccg taagaaccat actcattttc
    21481 aacctgcatc atgagaatat tgccaccatt gtccaacaaa cgaggcacca gtcttggcaa
    21541 taactgatca tagtagcgac caactgcctc gatatatgct gggtcggatg agcgaattcg
    21601 catgttcttg gtcaagagcc aagctggtaa gccaccgaat tcccattccg cacagataaa
    21661 tggagacgga cgcacaattg cgtagagacc caaatcctgc gctatttgga gaaatttctc
    21721 taaatccaga tcaccttcaa aatgaaactc accttcacga ggctcgtgta aattccaagc
    21781 aacataagtc tctaccgtat taaaaccaag agccttcaag ttatagagcg aatgatacca
    21841 atcctctgga ggaaccctaa aataatgaat ggcaccagat aaaatcttaa atgattttcc
    21901 atcgagatag aaatcatctc gtatctcaaa tcgtgtcata aaactacctt ccgaccgcga
    21961 aagtttgcgc tttcatttgt tgttatatta attataaacc aatctgtttg aattgtcaat
    22021 agaaattgtc gggatattta ctgcattttt actattatac acacattcaa ttagtttcaa
    22081 acatttttag acccatttca aacgctcttt aaattcggaa tataggacct aaaataattt
    22141 tgtatagaat acattgataa aatatgagca atccctatat cgcttaattt ttcagactat
    22201 tattctaatt ttttattcaa aagactacta tttttttcgc ttttatggta aaattttcta
    22261 tggagaagga aaatagaggt aaaaatatgg caattcccaa atatcaatac ataaaagacg
    22321 aattaaaaaa taaaatcatc tctgggcagt ttagcagtgg agataaattt tacactgaag
    22381 cagaactcat ttcaatgtac gatgtcagct ctatcacagt tgttcgcgcc ttaaacgacc
    22441 ttgccaaaga tggctatatt gtccgccaac aaggaaaagg aaccttcgtt tcacgtgcac
    22501 gcaaacacaa gcttgtagag ttttcagata ttgaactctt caatgctaaa gatgataagg
    22561 taactgttct ttcaattgaa cgcggaaaca agcttgttta cttggaaaaa ttgggtctac
    22621 gtggcgatca attctactac aagattgaac gtatccgcga atcaaacggt gtcgtttata
    22681 tctaccatac atcctacatc ccagaacaat atatcaacgc aaattatcca aaccttgaat
    22741 actatagttc tatctataat cgtttcaagt tagactacca cattcacatg aatgatgaac
    22801 actttgaaga aatcaacgaa atagtctttc caactccaga acatgcggct tcagtcctcg
    22861 gagtcgatga acaattccct actgtcctac aaactaaaat caccaaactc gaatcaactg
    22921 gccaagtttt agaatacagt gaaacttaca aacgatctga ttactacaag attaaattta
    22981 tctcatgtga ccgtgatcac taagaagaaa gcctgagcta atcgcttggg ctttttctat
    23041 gcttattata ccacaccaaa aaggtagcgc ttacctattt ttggaaaatt ctataatttg
    23101 tggaatattt tatagaaata gaaccaaaaa ttatactaga tatatatacg tattttttcc
    23161 gaccaatctg aaatcttaag tttaaatttt atattttttt atacttatta tagttttttg
    23221 tcatctcctc ttgactctcg ttaatataag aaataaaata aaggcgttga tttatataat
    23281 cgctatcaat ataacaatgc aatcaggagg ttttgcaatg aaacatgaaa aacaacagcg
    23341 tttttctatt cgtaaatacg ctgtaggagc agcttctgtt ctaattggat ttgccttcca
    23401 agcacagact gttgcagccg atggagttac tcctactact acagaaaacc aaccgaccat
    23461 ccatacggtt tctgattccc ctcaatcatc cgaaaatcgg actgaggaaa cacctaaagc
    23521 agtgcttcaa ccagaagctc caaaaactgt agaaacagaa actccagcta ctgataaggt
    23581 agctagtctt ccaaaaacag aagaaaaacc acaagaggaa gttagttcaa ctcctagtga
    23641 taaagcagaa gtggtaactc caacttctgc tgaaaaagaa actgctaata aaaaggcaga
    23701 agaagctagc cctaaaaagg aagaagcgaa agaggttgat tctaaagagt caaatacaga
    23761 caagactgac aaggataaac cagctaaaaa agatgaagcg aaagcagagg ctgacaaacc
    23821 ggaaacagag gcaggaaagg aacgtgctgc aactgtaaat gaaaaactag cgaaaaagaa
    23881 aattgtttct attgatgctg gacgtaaata tttctcacca gaacaactca aggaaatcat
    23941 cgataaagcg aaacattatg gctacactga tttacaccta ttagtcggaa atgatggact
    24001 ccgtttcatg ttggacgata tgagcatcac agctaacggc aagacctatg ccagtgacga
    24061 tgtcaaacgc gccattgaaa aaggtacaaa tgattattac aacgatccaa acggcaatca
    24121 cttaacagaa agtcaaatga cagatctgat taactatgcc aaagataaag gtatcggtct
    24181 cattccgaca gtaaatagtc ctggacacat ggatgcgatt ctcaatgcca tgaaagaatt
    24241 gggaatccaa aaccctaact ttagctattt tgggaagaaa tcagcccgta ctgtcgatct
    24301 tgacaacgaa caagctgtcg cttttacaaa agcccttatc gacaagtatg ctgcttattt
    24361 cgcgaaaaag actgaaatct tcaacatcgg acttgatgaa tatgccaatg atgcgacaga
    24421 tgctaaaggt tggagtgtgc ttcaagctga taaatactat ccaaacgaag gctaccctgt
    24481 aaaaggctat gaaaaattta ttgcctacgc caatgacctc gctcgtattg taaaatcgca
    24541 cggtctcaaa ccaatggctt ttaacgacgg tatctactac aatagcgaca caagctttgg
    24601 tagttttgac aaagacatca tcgtttctat gtggactggt ggttggggag gctacgatgt
    24661 cgcttcttct aaactactag ctgaaaaagg tcaccaaatc cttaatacca atgatgcttg
    24721 gtactacgtt cttggacgaa acgctgatgg ccaaggctgg tacaatctcg atcaggggct
    24781 caatggtatt aaaaacacac caatcacttc tgtaccaaaa acagaaggag ctgatatccc
    24841 aatcatcggt ggtatggtag ctgcttgggc tgacactcca tctgcacgtt attcaccatc
    24901 acgcctcttc aaactcatgc gtcattttgc aaatgccaac gctgaatact tcgcagctga
    24961 ttatgaatct gcagagcaag cacttaacga ggtaccaaaa gacctgaacc gttatactgc
    25021 agaaagcgtc acggccgtaa aagaagctga aaaagctatt cgctctctcg atagcaacct
    25081 tagccgtgcc caacaagata cgattgatca agccattgct aaacttcaag aaactgtcaa
    25141 caacttgacc ctcacgcctg aagctctaaa agaagaagaa gctaaacgtg aggttgaaaa
    25201 acttgccaaa aacaaggtaa tctcaatcga tgctggacgc aaatacttta ctctgaacca
    25261 gctcaaacgc atcgtagaca aggccagtga gctcggatat tctgatgtcc atctccttct
    25321 aggaaatgac ggacttcgct ttctactcga tgatatgacc attactgcca acggaaaaac
    25381 ctatgctagt gatgacgtta aaaaagctat tatcgaagga actaaagctt actacgacga
    25441 tccaaacggt actgcactaa cacaggcaga agtaacagag ctaattgaat acgctaaatc
    25501 taaggacatc ggtctcatcc cagctattaa cagtccaggt cacatggatg ctatgctggt
    25561 tgccatggaa aaattaggta ttaaaaatcc tcaagcccac tttgataaag tttcaaaaac
    25621 aactatggac ttgaaaaacg aagaagcgat gaactttgta aaagccctca tcggtaaata
    25681 catggacttc tttgcaggta aaacaaagat tttcaacttt ggtactgacg aatacgccaa
    25741 cgatgcgact agtgcccaag gctggtacta cctcaagtgg tatcaactct atggcaaatt
    25801 tgccgaatat gccaacaccc tcgcagctat ggccaaagaa agagggcttc aaccaatggc
    25861 cttcaacgat ggcttctact atgaagacaa ggacgatgtt cagtttgaca aagatgtctt
    25921 gatttcttac tggtctaaag gctggtgggg atataacctc gcatcacctc aatacctagc
    25981 aagcaaaggc tataaattct tgaataccaa cggtgactgg tactacattc ttggtcaaaa
    26041 accagaagat ggtggtggtt tcctcaagaa agctattgag aatactggaa aaacaccatt
    26101 caatcaacta gcttctacca aatatcctga agtagatctt ccaacagtcg gaagtatgct
    26161 ttcaatctgg gcagatagac caagcgctga gtacaaggaa gaggaaatct ttgaactcat
    26221 gactgccttt gcagaccaca acaaagacta cttccgtgct aattataatg ctctccgcga
    26281 agaattagct aaaattccta caaacttaga aggatatagt aaagaaagtc ttgaggccct
    26341 tgacgcagct aaaacagctc taaattacaa cctcaaccgt aataaacaag ctgagcttga
    26401 cacacttgta gccaacctaa aagccgctct tcaaggcctc aaaccagctg caactcattc
    26461 aggaagcctg gatgaaaatg aagtggctgc caatgttgaa accagaccag aactcatcac
    26521 aagaactgaa gaaattccat ttgaagttat caagaaagaa aatcctaacc tcccagctgg
    26581 tcaggaaaat attatcacag caggagtcaa aggtgaacga actcattaca tctctgtact
    26641 cactgaaaat ggaaaaacaa cagaaacagt ccttgatagc caggtaacca aagaagttat
    26701 aaaccaagtg gttgaagttg gcgctcctgt aactcacaag ggtgatgaaa gtggtcttgc
    26761 accaactact gaggtaaaac ctagactgga tatccaaaaa gaagaaattc catttaccac
    26821 agtgactcgt gaaaatccac tcttactcaa aggaaaaaca caagtcatta ctaagggcgt
    26881 caatggacat cgtagcaact tctactctgt gagcacttct gccgatggta aggaagtgaa
    26941 aacacttgta aatagtgtcg tagcacagga agccgttact caaatagtcg aagtcggaac
    27001 tatggtaaca catgtaggcg atgaaaacgg acaagccgct attgctgaag aaaaaccaaa
    27061 actagaaatc ccaagccaac cagctccatc aactgctccc gctgaggaaa gcaaagctct
    27121 tcctcaagat ccagctcctg tggtaacaga gaaaaaactt cctgaaacag gaactcacga
    27181 ttctgcagga ctagtagtcg caggactcat gtccacacta gcagcctatg gactcactaa
    27241 aagaaaagaa gactaagtct tttcgataaa aaataaacag cgagattgaa gctcgctgtt
    27301 tattttttaa ttaatcacct agtccaagac gttcaaagat atcatccact cgtttggtgt
    27361 aataaactgg gttgaagatt tcatcgattt cttcttgagt gagacgtgat gttacttctg
    27421 aatctgcctc aagaagtggt ttaaagtcta cttggttgtc ccaagagtag gctgtttttg
    27481 gttgcaccaa gtcataggct tgctcacggg tcatgccttt ttcaatcaat gtcaacatag
    27541 cccgttggct aaagataaga ccaaaagtcg agttcatgtt tcggatcata ttttctggga
    27601 agactgtcaa gttcttgacg atatttccaa aacggttgag catgtagtca atcaaaatgg
    27661 tcgtatctgg tgtgatgata cgctcagctg atgagtgaga aatatcgcgt tcgtgccaga
    27721 gagcgacgtt ttcataagcc gtaatcatgt gaccacgaat gacacgcgcc agaccagtca
    27781 tattttcaga accgattggg ttgcgtttgt gaggcattgc tgaagaccct ttttgccctt
    27841 tagcaaagaa ctcttctact tcgcgttgct cagatttttg tagaccacga atctcagtcg
    27901 ccatacgttc gattgaagtc gcaatgctgg caagaaccgc aaagtactca gcgtgaaggt
    27961 cacgaggaag gacttgtgta gagatttctt gggcacggat gccaagttta tcgcagacat
    28021 actcctctac aaatggtggg atattggcaa agttcccaac cgcaccagaa atcttaccag
    28081 cttctacacc agcagctgca tgctcgaaac gctcgatatt gcgtttcatt tcgctgtacc
    28141 aagttgccaa tttaagacca aaggttgtcg gctcagcgtg cacaccatga gtacgcccca
    28201 tcatgatggt gaacttgtgc tccttggcct tgtcagcgat gatattagtg aagttttcaa
    28261 ggtcacgacg gatgatgtcg ttggcctgct tgtagaggta accataagca gtatccacca
    28321 cgtcggtaga agttaaccca tagtgaaccc acttgcgctc ttcaccaaga gtctcagaaa
    28381 ccgcacgcgt gaaagccacc acatcgtggc gcgtctcctg ctcaatttcc aaaatacggt
    28441 cgatgtcaaa gtccgccttc ttgcgaatca aagccacatc ttccttaggg atttccccca
    28501 actcagccca tgcctcgtca gagaggattt ccacctcaag ccaagcacgg tatttatttt
    28561 cttcactcca aatattcgcc atctcagggc gagagtaacg gttgatcatg tgttaatttt
    28621 tcctttcttc ttaagctgtt gggaataagc tatctaggta aaccaagatt tctactcaaa
    28681 ctcctctttt tcaataaaca cagacgggta atgatctagt gtattcaaat ccgtatccag
    28741 cggtacatca tagatagcta aataattttc ggggtattgt gcagctagtt cttcatattt
    28801 agcttttacc ttatcttggt cagcactggc atacaacact tcaacaactg ctccagtctt
    28861 atccttttca ataaatgtat taacgataat ttgtatcata gacttgtcct aaaaatcaat
    28921 cccttcccca agctcatcca cactatccgg tacatcacta aacaaggtca catgtcccat
    28981 cttgcggttg tgcttcgctt ctattttacc atacatgtgg aggtgggcgc ttgaattttc
    29041 tgtcacatat tgctcagcag cctcgacatg ctgaccgagg acattaagca taacggctgg
    29101 cgcatggagt ttgatgactg gtaatggtgc tccgagaaca ccgagaatat gggtgtcaaa
    29161 ctgagagaaa tcacaggctt caatagaata gtgcccagag ttatgtggtc gtggggcgat
    29221 ttcattgaca ataacgtcat catcagtcgc aaacatttcc acacagagag ttccagacaa
    29281 gttgagttgt tctgcgattc gcactgccat agctttagcc ttgtctacta gactttcaga
    29341 aatgcgggct ggtacgatgg tcttagacag gatattgttg cggtggatat tttcctgaac
    29401 tgggaaaaac gtcacctcct tgccatttcc tgacacgatg acagaaatct caaggtcaaa
    29461 gttgacaaat tcttccaaga cgcagtctgc tgagtctgct agcgcatagg ctgcttccaa
    29521 gtctgcttct gaacgaataa ccttttgtcc atgaccatcg tagccaccag tcgcagtctt
    29581 gaggacatag tttttcgaca agtcgatatc tgccaagtct aggctagaag tcacgacctt
    29641 gtagggtgcc acagtgactt gagccttgtt tgacaaaaag tccttttcaa aaatacgatt
    29701 ttgcgaaatg cggagcagat ctgttccttg agggagttgt ccatccttga taacggcatc
    29761 caaaccgtca gcgtcgacat tttcaaactc ataagtgagg acatcgcaac ggtctgccaa
    29821 ctgacggagg gcgtccacat cgttataagg tgccacaatg atttccgcca cgcgagaggc
    29881 cgggcaatcc gccgcaggat ccagcgcgat aaccttgtgg cccatgtaga tagcagaaat
    29941 ggccatcatc tgacccagtt gaccgccacc gataattccg attgttttag atgagctcat
    30001 ttgacgactc ctctgcgatt tttccttgtt cttcagcaaa gttggcaagt gcatccgcaa
    30061 tggacttatc ttctacagag aggagacgga gggcaaagag agctgcgtta gtcgctccag
    30121 cttcaccgat agccatggtc gcaacaggca ccccacccgg catctgaacg atagaataga
    30181 gtgaatccac tccactaaga gcacgagact tgactggcac accaatgact ggaagggttg
    30241 ttttggcagc taccatgcct ggcaaatgcg ctgcgccacc agcacctgcg atgatgatct
    30301 tgatgccacg actacgggct tcttctgcat gtttgaacat gaggtctggt gtacggtgtg
    30361 cggaaacaac tttcttttcg taggctacac cgaagcggtc taggacttct gctgtttttt
    30421 gcatggttgc ccagtcggat tttgagccca tgatgatgga aattactggt ttcatttctt
    30481 ctcctttttc ctctttttca acaatcacct tagcttgtga gggacggcag cagccaccaa
    30541 aggtgtctca tgcctaaatt ggaaacccaa ggtcttccaa tttccctgaa cgattggatt
    30601 atcatccaat cgttctttca caacggcggt gattgttcta tattagctcg ctaacgctcg
    30661 caaaccatac gatcattaac gtattttgtg aatttttatt tttctttttg ataatggtct
    30721 taggtgatgg aggcggaagc aaaccttcgg tttcattcct aaactttgag cctacggtct
    30781 ccaagtttcc ccctgaccag aacattcact gttctggtct tttcaccacg acgaccatta
    30841 tcgtgtttgg cgactacggc gcgttattct tatatcttta cttaattgcc ttgcttccga
    30901 tatctgttcg gtagaagagt ccttctattt tttgttggta tagttcttgg tagatgctgg
    30961 cttgggcttc tttgacggta tctgctgtgg taacgagcat ataaactcgt ccgccgtttg
    31021 agagcagtgc tctgctattt tccgcaaact tagcccctgc atagtaggtg atgacatcgc
    31081 cttctgtctt ggctggcaac tcaacgcccc tttcatagtc tagcgggtag cccttggatg
    31141 cgacaaccac acccagagtc acacccttgt ccgtccacat gatatttggc tccttgctat
    31201 ccaggatatc tgtgatattt tgagcaaagt cagaggtcaa gcgaggcaag ataatctgag
    31261 tttctggatc tccgaaccga gcgttgaact caatgacttt cggtccatca gctgtcagga
    31321 taagccctgc gtaaagaact cccagataag ggcgaccttc tttaatcatc ccttctagaa
    31381 ctggcttgac aatggtgtca accgctgtat caactacact ctgtggtaag tgtggaactg
    31441 gcgcataggc acccatacca cccgtgttag gccctttgtc gccatcgtag gcacgtttgt
    31501 ggtcctgagc cgttggcatg atgtagaact tatcaccatt aacaaaggca aagagtgaaa
    31561 attcctctcc ttcaaggaat tcctcaataa ccacgcgcgc acctgagtca ccaaatttat
    31621 tgtccaaaag catctcatga gcggcttcga ccgcttgctc aaccgtctca gaaacgacga
    31681 cacccttccc aagcgccaag ccatccgcct tgactacgat aggcgcacca tgcttttcga
    31741 tataggcctt tgcttcctcg aaatctgaaa atgtgccata ggctgctgtc gaaacaccat
    31801 atttgaccat gatttccttg gcaaaatcct tggaccactc cagctccgct gcagccctag
    31861 tcggaccaaa ggccttaagc ccagcttggt taaaatcatc cacgatacca gcagcaaggg
    31921 catcatctgg accgataaag gtccaagcaa catcattggt ctttgcgaag tcaatcaatt
    31981 tagaatgttc ggaaatagag atatttacca attccaaacc atccagagtc atcccatcat
    32041 tcccaggagc tacaaagact ttttcaacgt cttttgattc aagtaacttt ttagcaatcg
    32101 catgctcacg accacccgaa ccgacaacaa gcagtttcat tcctcaacct cttttgcgaa
    32161 ttatttacca atattatatc aaaaaagttc gttttaatct tgtttcagtt agcattttaa
    32221 gccaaaaaag gaaagaaact gttttcttcc cttttatctt cttaatgtct aaaatgtctc
    32281 acacctgtaa agaccatagt caagccgtat ttatccgctg cttcgatgga ttcttggtca
    32341 cggacagagc caccgggctg gatgatggcc ttaattcctg ctttggcgat ttcttccacg
    32401 ttatccgcaa atgggaagaa ggcatctgaa gcaaggaccg ccccgttcag acgatctttg
    32461 gcttggtcaa tggcaaggcg aacagaagcc acacggttgg tttgacctgg accaacacca
    32521 agtgtcatgt ggtcgttggt cacgataata ccatttgatt tgacgtactt gatagccttc
    32581 caagcgaact caagagcagt cgcttctgtc tcagttggct gacgtttggt caccacttgc
    32641 cagtcagctg ggctttcctt gaccacgtct tgattttgca cgagaagtcc accgactaca
    32701 cctgtgtatt ctgcttccac ttcgctagcc tcttgagcat taaatggcaa ggcaaggata
    32761 cgcaagtttt tctttttatt gatcaaaata gctagcgctt catccgtata gcttggtgca
    32821 atgatgattt cgaggaaaac gccgtgcatc ttctcagctg tcgcagcatc cacctcacgg
    32881 ttgaggacga caatcccacc aaagatagac actgggtcag actcataagc gtagtcccaa
    32941 gcagtctcaa tgttatcagc ctgaccgatt ccacatgggt tcatgtgttt gagagccaca
    33001 acagttggac ggtctttgaa atcacgaata atacgaatgg cagcatccgc atcacggata
    33061 ttgttgaagg acaattcttt accattgagc tgtttggctg aagcaatgga gtagtctgtt
    33121 ggcaaggctt tttggtagaa atccgcgtct tgttgagggt tctcaccgta acgcatggct
    33181 tgcttgaggt cataagtcaa ggtcaacttt tcaggcttgc tttcacccac ttgagctgtg
    33241 aagtattctg caatcaaggc gtcataagcc gctgtgtgac gaaatacttt ggctgctaaa
    33301 cgttggcgag tttcataagt cgtttcacca ttggctgaca actcgtccaa aaccacagcg
    33361 tagtcagcag gatctaccac aactgtaaca ctggcatgat ttttcgctgc tgaacgaagc
    33421 atagatggcc caccaatatc gatattttca actgcatcag cataagtcac atctggttta
    33481 aggatagttt ccttaaatgg gtaaaggttg accaccacaa ggtcaatgag ctcaatcttg
    33541 ttgtccttag ccgcttccaa gtggctatcc aagtcacgac gagcgagaag ccctccgtgg
    33601 atatttgggt ggagtgtctt cacacgaccg tccatcattt ctgggaaacc agtcatatca
    33661 tcgatagcaa tggtatccac cccagcatta tcaagggcaa ccttagttcc acctgttgag
    33721 ataatctccc aaccaagttt tttgagttct tgggcaaatt caacaatgcc cgctttgtct
    33781 gagacgctga ttaagacgcg tttagtcatt atattctcct ttttaatcat tagttaaaca
    33841 ccaattaaat gcagtaacag taaaacaaga taagcaaaac caaggctaag catacctaag
    33901 atattgatcc attttctagt ctgtgatttg aacactctta taaaaatttg ataaatcagt
    33961 aagcctacac agacacctag cgtatttaaa gtcaaatccg ttatatctgt tatacctatt
    34021 gctaaaatat actgtaagca ctcaaacaat aaactaatca agaaacctgt cccgactatt
    34081 cttaaactag ataaattagt ttttatcaaa gggaaacaaa cacctaatgg aataaaggaa
    34141 atcagattaa ataacatttc agcaaaaaca atttttccat cgactattag tggttctgaa
    34201 aatggaatcc aattgatata ccttggagct aagaaaaatg ctataaattc aggatttgtt
    34261 tcaaacttaa ataagattcc ccaagttaat aacatcagat agacataaaa tacatatcga
    34321 gttgtttttt tagattctaa cattacaaat acctccgttt gaagccgtct tcaacaaaca
    34381 ctgactccaa tttaaaatca aagatatcat atgaatcatc aaaaagtcaa tctgtaaata
    34441 gagccttcac tacttccgga tacaacctgt actctgcttc atggatgcga gcttcaaatc
    34501 tgtcaatggt atcatcagct agtcgtggca cacgaacctg tttgatgacc tggcctgtat
    34561 ccacacccga atccacccag tgaatggtca caccagactg acccacgcca gcattccaag
    34621 catcctcaat cccatgagct cctggaaatt ctggcaagta ggctggatga atgttgacaa
    34681 tccgaccttc ataagccgac aataaggttg gtccaactat tttcatgtag cctgctaggc
    34741 aaaccaagtc aatctggtgt tcttccaaga gttcgacaag ggctgcttcg tagtctgcct
    34801 tgctctcaaa ctccttgagt tcaaaagcat aggacagaac gccgagctgc tttgcacgct
    34861 caagcacata ggcatcacga tggtctgaaa agacaaactc cactggaaat tcttcggcaa
    34921 tcacctgaaa atttgagcca ttaccagagg caaaaaccgc tatttttttc atttgataat
    34981 gacactttcg ttttctttct tgacgatgcg accaatttca tagactgctt catccaacaa
    35041 ttcttttaca cgctctacat tttcagggct gaccgccaac atgagtccca cacccatatt
    35101 gaagatttca aacatttctt cgtgtttaat ctgaccgtat ttttcaaggg ctttgaaaat
    35161 tggaagcact ggaactttgc tttcatcaat ttcagcagct aggtcatctg caaacatacg
    35221 agggacattt tcgataaagc caccacctgt gatgtgggca atgccgttga ccaactcttc
    35281 tttgatgagc ggcaagacag ccttgacata gatacgagtc ggctcaagta gaacttcctt
    35341 aagtttcttg ccttccaatt ctggtaggac ttcctcacct gtgtaatccg caaagacacg
    35401 acgaaccaaa gagtaaccat ttgagtgaat cccacttgaa acaagtccga gaagaacatc
    35461 tccctctacc acctttgaac cgtcaatgat ttgagatttt tcagccacac cgaccgcaaa
    35521 accagccaag tcatagtcgt cttcgccgta catgcccggc atttcagccg tttccccacc
    35581 gatgagggca gcaccagcct gcacacaacc ttctgccaca ccagcaacca cttgttctag
    35641 cttagctggt tcattcttcc ctgtcgctac gtagtcgaga aaatagaggg gttccgcacc
    35701 tgcagcaatg atgtcgttga cacacatggc cacacagtcc tgcccgatgg tatcgtgctt
    35761 gtcgtacttg atagccaaca tgagcttggt tccgacaccg tcagtccctg aaatcaagac
    35821 gggttcttta accccagtct tggaaaggtc aaacatacca ccaaagccac caagagctcc
    35881 catgacacct gcacgctccg tacgggccac gtgcttttta atccgttcaa caacttcata
    35941 acccgcttca acatccacac ccgactgggc atatgcattt ttatttgtca tttgtttttt
    36001 ccttttcttt aatggagaat ctgtcgccta cttgtaaaaa ctggtctttt cttccaaact
    36061 tctacgatag tcttcttcgt agtcatagag aggcgttggg tagtcaccgt caaagtaagc
    36121 gacacagaga ccaccgttcg gcgcatctgt ttcgatacca atcgactcaa tcaagccatc
    36181 aattgaaaga taagtcatac tgtccgcacc aatgatttgg cgagtttctt cgaccgtatg
    36241 attggctgca atcagctcct gacgggtctg gatatcaatc ccgtagaaac atggatacgc
    36301 tagtgcagga cttccaatgg caacgtgaac ctcagtcgca cccgcttctt tcaagagctg
    36361 aacgatacga cgagaggttg ttccacgtac aatggaatca tccaccatga ccacacgttt
    36421 gcctttgaca acacccgaaa cagcagacag tttcatccgc actccttgct cccgcaattc
    36481 ttgagtcggt tggataaaag ttcgctgggt gtattggttt ttgatcagac ccatttcatt
    36541 tggtaagcct gattcttccg caaatcccat agccgcgctt agggaagaat tgggcacacc
    36601 aactacaata tctgcctcat gcttaaattc tcgcgccaat tgcgctccca ttctcttacg
    36661 tgccgtatgg acattgacac cgtggatatt agaatcaggg cgagcaaagt agatatactc
    36721 catagaacaa atcgccaact gggtatcatc tgtatagctg tcatactgaa tgccctcgtc
    36781 atcaatgatc acaatctcac ctggcttcaa atcacgaatc cactcggcac caataacctc
    36841 aaaagcacag gtttcagaag atacaacaac tgctccatta gccattttcc cgatagaaag
    36901 cggacggaaa ccattggggt caagagccgc aatcaacttg tcctcaaaca gcaagatata
    36961 ggcaaaacca cctttgacaa ggctgagcgc ttccttgatt ttgcccatca ggctaggatt
    37021 atgactgcga cgaatgagat gagccaagat ttccgaatcc gaagtcgcac tgaaaattgc
    37081 tcctctatct tccaattctt tcttgagaga ggctgcattg gtcagattcc cattatgagc
    37141 caagccaaac tgcatatcgt gaaaacggaa gaggaagggc tggatgttat ctacagaagc
    37201 ttcgccagca gtcgcataac gcacatgccc aatcgcacca gtccctgtca atttatccaa
    37261 attagcagga tttctgaaga cttctgataa aagtcccatg tcacgatggc gctttagttt
    37321 tccttggtca ttggagagga ttcctgcccc ctcttgacca cggtgctgaa gactgtggag
    37381 tccaaaatag gtcaacttag cagcatctgg atgtccccaa ataccgaaaa caccacattc
    37441 ttcattaaga gattttactt cgtatgtcat tttttatacc taattttcat ttgtaatcat
    37501 caagagctag atttacatga cttttacatt actgatacta tctattagaa aatctgtaag
    37561 tcttattttc cagtgaaatg tttaaccgct gacgcgaaca ggtgctggtc tttattgcct
    37621 gggatatttt ggaaaagacc gtcctcataa cgttctgagt ggcccatctt accgatgatt
    37681 tgaccattct tgctggtaat tccttcgatg gcatggacag aaccattcgg attgtactta
    37741 gaatccatac ttggtttacc gttaaagtca acgtattggc tgaaaatttg tccattgtca
    37801 cggagctctg caaattcctc agccgtcacg acaaacttcc cttcaccgtg cgaaacagga
    37861 atagcgtgga tatcgcccac ttgcacacca gccaaccatg gtgagttggt attggcaatg
    37921 cgagtttcca ccatcttggc cacgtgttgg ttggcatcat tgtagaagag ggttgggcta
    37981 gtactgttag caacttcaaa gtttccgtag ggtaggagac ccgatttgac taaggcttgg
    38041 aatccattac aaataccgat aatcaaacca ccacgggcga taaagctatc aatagccaca
    38101 cgcacttttt cattaagcag gatattgacg ataaacttag ctgaaccatc tggttcatcc
    38161 gcagccgaga atccaccagc aaagaagaga atattagtct tgtcgatatt gtcaaccata
    38221 gtttcaactg acttgacaat agcttcttca ttcaaggtca cgaatggcac caaattgacc
    38281 tctgcacctt ctttttcgaa ggccttagct gaatcatatt ctgagttggt tcctggaaag
    38341 actgggatgt aaaccacagg tttttcaacc ttttctttgg ctttaatcac aacatctgat
    38401 gccacagctg gtacttcttc tagttctttc gcttgggtaa attctgttgg gtaaacttct
    38461 tccaatgtcc cttgaaatgc actgtcaagc ttgtgtccat ctagcttcac accgttgaca
    38521 gtcagtgtaa agtctgcttt cgtttgtcca accttctcta ctccagcaat ttcttcagga
    38581 gatgtgaaga caaagccgcc taattgagct gtcaaagctg tttcaagttc aggcaaggtc
    38641 acctctgcac caatatagtt tccaaaggta gcaagagcca aactttcaac tacaccaccg
    38701 tatttgacag ctgatgcaga tgtcacttta tggtcagctt ggatggcttc aaactgagca
    38761 aaatttttct taatcaagtc aaaatcaatc tctgcagaga gggcttgacc tgggatgtag
    38821 tagatatttt ccccaacagc tttaaattct ggagagagca ccttacggct atctgccgtc
    38881 gtcaccccaa aggcaaccaa ggttggcgga acggtcaatt cttcaaaggt accagacatg
    38941 gagtccttac caccgataga tggcaagcca agctgaattt gtgcttcaat agaacctaga
    39001 agagcagcta ctggctgacc gaaacgctct gcttgtttat ccatacgctc gaaatactct
    39061 tggtaagaga aacgagcctt ggaccagttg gcaccagcag ccaccaaacg agcagttgct
    39121 tcgataaccg cataagcagc accgtggtat ggagaccatt cagctacata tgggttgaaa
    39181 ccttgagcaa tgaccgacgc agtatgagtc acaccgtgtt gaactggcaa tttctgcaca
    39241 gatgcctcag ttggtgtgag ttggtaacga ccaccaagtg ggtgattaac cgttgagcgt
    39301 ccaacagagc agtcaaagat agtctgtaat cctttttgac ttgcatggtt gaggtcagat
    39361 agaaccgtaa gggtatctga ttccagtgtt tcagcagatg tttgacgctc ttctgggagt
    39421 ttgacatcct tgtccacaac tttggcatcg acaaccacgc gcacaccatt ggtgtcaagg
    39481 aaacgacgct ccaagtcaac gattgtctca ccattccagt gcatgacaag atttggtttt
    39541 tcagttacta tcgccaccac aacagcatca atattttctt tgttacattc ggcaacgaag
    39601 gcatccacat cttcaggacg aaccacgacc gccatccgtt cttgtgattc agagatggca
    39661 atttctgtac cattcaagcc ctggtattta agaggcacct tgttgaggtc gatttcaaga
    39721 ccgtctgcca attcaccgat agccacacag acgccgcctg ccccaaagtc attggacttc
    39781 ttgatcagac gagtgacatt gccattacgg aagaggcgct gaatcttgcg ttcttcgatg
    39841 gcatttcctt tttgaacctc agcaccagca gtctctacag actcaactgt ttgaacctta
    39901 gaagagcccg tcgcaccacc gacaccatca cgacctgttt tgcctccgag aaggatgatc
    39961 acatcacctg cttcaggttt ttcacggaca acattgccct tgggagccgc accaacaacg
    40021 gcaccaagtt ccatacgttt agctacaaag cctgggtgga agtattcacg aacgtaggtt
    40081 gtggcaagcc caatctggtt accatatgaa gaataaccat gagctgctgt tttagaaatg
    40141 acttgttgtg gcaatttccc agcacgagtt tccgaaatcg gtgctgtaat atcaccagca
    40201 cctgaaatac gcatggcttg gtaaacatag gaaaggcctg acaacggatc acgaatagct
    40261 ccaccgatac aggtagccgc tccaccaaat ggctcaattt ctgttggatg gttgtgggtt
    40321 tcatttttaa acatgaggag ccaaggttcc ttgacaccat caacatccac ttcaatttca
    40381 actgagcagg cattgatttc gtcagagact tccatatcat ccaatcgtcc gttagcacgc
    40441 tcataacgac cgaaaatagt cgccatatcc atcaaggttt gtggtttttc agaccgacct
    40501 aactcctcgc gcatggcaat atacttgtca taggttgact gcaattgctt ttgaaattta
    40561 gaagctgaaa agtcgatgtg tttcaactct gtctcaaaag tcgtatgacg gcagtggtca
    40621 gaccagtaag tgtccaaaac cttgagttca gtctcagttg gcacgcgccc gattgactta
    40681 aagtagtctt ggataaagag caaatcatcc acttccatgg ccatcccttg ctcggccttg
    40741 tagcgagcaa agtcttctgc tgtatagctt tcaaagaaag tcaattttgg aatggtcttg
    40801 tctgactctg aaaactcctg cttggcaatc cctgtcgtga tatccttgaa acgagaatca
    40861 actggattga gcaggtagtt tttgacagct tccaactcag tcgcatcaat atctttattc
    40921 accaagtaaa gttgggctgt gttgactgtc acgtcactcg aacttcccaa caaaagcaag
    40981 gcttcctgtg acgaagctgc acgctggtca aactgccctg gcagactttc aatggcaaag
    41041 aaagcatagt tagcaagatc cgcctgcaca gatacttcat ctaaaacatg gtcggttccc
    41101 tgctcagaga aaatgtgctt ctctgcaggt gcaaacaagt cctcagccaa gtcaaataca
    41161 tcatatactt gcacaatacg aatacttttc aagcttgaca gtcccacgtt gtgctggagc
    41221 tctctaacca aactctctga cttgacctga aaatcagcct ttttttcaac aaaaatacgt
    41281 ttatccatca attcttattc ctttatttca gctcttgcaa tattcccaaa cagccttgag
    41341 gttgttattt taaaccctgc aacttttccc aaacaatctc ataaacgtcg gttagttctc
    41401 ccaatcctct acggaaaaca tccttatcca tgtggttgcc atcagcgtcc cacaagcggc
    41461 agttatctgg tgaaaattcg tctgccaaga taatcttgcc atccttgtca aaaccgaact
    41521 ctagcttaaa gtcaatcaat ttaagcccaa tctcagcaaa ccagactttc aatagttcat
    41581 tgatacgacg cgtttcttcc ttcaagtagg caatctgctg gtcacccgca atctgtagga
    41641 atttcacatg ctcatcattg ataaatggat catccaaatc atcatttttg tagtaaaatt
    41701 cgacaatcgg agtctccaag gcgattccct catccacacc aaaacgtttt gaaaaggaac
    41761 cagcagtata gttgcggagc acgacttcca aaggaataat cttaaccttt ttattgagtt
    41821 gttccgtgtc tgaaagtttc tccacaaagt gagtcgccac accagccgca tttaatttct
    41881 caaaaataaa agatgaaatc tgattattca agactccctt acctgcaatc tgctccttct
    41941 tgacaccgtt gaaagcagtc gcctggtcct tgtaagttga aataataaga ttttcatcct
    42001 cagttgtata gatatcttta gcttttcccg aatagatcaa ttgttttgac attttaaagt
    42061 tcgcctttcg tattacttga gcacatttta ccacaaaaaa ccaaaaaaca caagaattca
    42121 accgaataaa tagcagatgt ttttcaaaaa ttgtaaagaa aaaactgcaa gaagaatctt
    42181 tctcacagtt taaaaattat ttaactctaa aaacacgaac attactcttt gttcaaaaat
    42241 tgatccaaat aataacgtag gtaacttttc ttgcccgtaa tcatctgtag acggccttcc
    42301 accccgtacc taagtttttc agcctgctcc gaagttagat tagtctccgc ctcgatttta
    42361 aagaaattcc ctttctcagt cttagtagct gtcgcatcaa tacttgtaat agtagaatct
    42421 agaaaaagtt gattcccggc atcatgagtc gtagtatagc gaacagaatc accgaccttg
    42481 attcttgcta catcttttga acttagatag gctgtgagtt tggctttccc ttctctttcc
    42541 aaagatggat aaagttgggc tagtagggca ccttctgcaa ccatgctaga atcactggtc
    42601 tcaggattaa gatgaagcac cccatcctca cttgccgtaa ttttcccctt gtctaaaaga
    42661 tttccctgta ccttcttacc tgactctgcc tccaagattt tctgggctag aagggtcaat
    42721 tcctgaccaa cctttgccaa gtgttgggat ttaagggatt ccaattgact gcttaaccct
    42781 gacgcatagg cttgctgggt acctgaacct gcatactgga cacggtaagt agcaagacta
    42841 gattctaact gagaaatctg tgcttcaacc tgtgcaactg cctgaacctt agtttgggga
    42901 ttttcctcgc cctgagactt gtaggactgg taaagagagt aggctagatt ctgactggcc
    42961 aaggaagcac ctgtttccat agctgactta gctgtctggt aatcgcgaat tttagcctct
    43021 gtttgattga tgaggttgcc gatttcggct tgggtttggc tagctgctgc attctgggac
    43081 gcgatggtct cattttgttg cgatgtacta gccctaagac tgcctgcttg actgatgtag
    43141 tcgcgaaagg tggcttggta gccaaactta tcctcctctg gaaagtggtt ctccccttct
    43201 tgcaggctct tttgcagata ctccaattgc tttttttgat cctttagcat gtccaactga
    43261 ctggcatagg actccgcttg gacaccctct gccccttctt ggtattgaac caaaagatcc
    43321 tccttcttaa ccagcttatt ttcttccaaa tgattgacaa gaatacgatt gttgctagtt
    43381 gactggatat ttgcaaggat acgactaggt tcgacagtag ctctagtgga caagctcatc
    43441 tccttttctg caacagttgc aaagccaagt aaaaacacga gcagaagggc catgggtaca
    43501 atcacactac tggaaaaatt atggtaacga cgattataaa actccgcact ttctaaaaat
    43561 tctggtttca tcctctcctc tttctagcta ttgaccaaat gggcgtaaaa gccaccctgt
    43621 gcaagcaaat cagcatgctt tccttcttcg acaatcttgc cctgatccaa gacaaccacc
    43681 ttctctgtcc gctcagcaat agtcaagcgg tgagcaatga aaatcaaggt cttgtccaaa
    43741 gccatgagat tatcgacaat ccgcttctct gtcaaaatat ccaaactgct agtcgcctca
    43801 tccaaaatca agaccggcgc atctgtcaag agagcacgcg ccaaagcgat tctctgacgt
    43861 tgaccacctg aaatccctgc cccatccgaa gtcaattctg tctgataatt cagtggcatg
    43921 cgctcgatat cctctcgaat ctctgccaat tcgaccgccc gtaagatatc ttcctgtgtc
    43981 gtcccctcct tggctcccaa aagaagattc tccaaaatcg ttccgttaaa gacatagggc
    44041 tgttgaggca gatagtttat gtactggcgc agggcttttt tatcaatctg attgagattg
    44101 acactaccca gactaatctc cccttgactt gggtcgtaaa aattaaccat catcttggcc
    44161 aaagtcgtct tacctgaccc tgaaatcccc acaaaagcca ccttagaccc ttggggaacg
    44221 gttaaattga tatccgacaa gacgtctcga ccatagccat acttgtaatg aacctgcttg
    44281 aaggtcatat ctcccttcat caagctcaaa tcctcaactg ttttcttctc ctcaaactca
    44341 gaagctacta gatacacttc atttagacgg ttattggcaa cctgcgctgt ctgaagcttg
    44401 gtttgcagat tgatgatatt ttccaaagga ttggtaaagt aaaccagcaa ggtattatag
    44461 gtaatcaact gccccaaact catcttgcca tccatgacca gaacagcccc catccagaga
    44521 atgccgacat taagcaagag atgggcaacc tttttcagag ccttttgctg actctctgct
    44581 cgactatagg taaaggattt cttcagataa tccacaaatt ccttgtcaat tttttggtaa
    44641 cgctgacttt cactggtcaa ggacttgata gtctcaatac cgttgatgtc ctcaatgata
    44701 gaagaagaca gaaccgcatt ggcttccatg gtatcccgat tcatcttttc aaacggcttc
    44761 ataaaggcaa agataatcac tgtgtagata ggaagcgcca ataaagtcat gaaaaagaga
    44821 ttggtatttt gtgaaaatag aacaagggaa ataatgacaa ccgttgacac atctaggaaa
    44881 atcgaaagga tggtcgaagc cagcgcatcg atgatactgt tagcatctgt aaaacgagac
    44941 acgatttccc ctgtcctgcg tgtcgcaaag aaggacatag ggaggtgaaa aacatgcttg
    45001 atataggaca aaatcacgtc aatcgacaag cgttgcccca aaacaagcaa gagatactcc
    45061 tgagcgtaag acaagatttg ctggaggatg tagacgatga ctagcccaat agaaataatc
    45121 cctagtgtcg aacgcatctg atctggcaca taggtatcaa tgatagactg cagataataa
    45181 gaacccacaa tgttaatcac ggttaccaag agtgttgcca aaacgatatt ggcaatcaag
    45241 ccacgctgct tcactaatat agggataaaa gagaacagac catttttttg ttccttatga
    45301 ggcttgtagt ctggactagg tgccataaaa agagtcactc ctgtccattc ttccgcaaaa
    45361 cgctcacgtg gcagtttggt caacttcacc ccgggatctg gatcggcaat atgaatgcta
    45421 tccttatcct gcccagtcac cacatagtag tggagcaatt tcccttcctt aagcacatgg
    45481 gcaacaaaag gaaaagtcaa atccggcaag tcaaaaagcg tcatatccgc cttaatggct
    45541 cgcgtctcaa aaccaatctc ctctgccacc ttgaccaagc ccaaagccgt cgttccatcc
    45601 atggtcgtct tagccaattc tcgcaagtga gccaaaaaat aataactacc atagtagcca
    45661 aaaaccatgg ctaatgaagc tacaccgcag tccatctgat ccacttgcgg acgatagtga
    45721 cgtttcccaa atttcatatt catctccttt tccctaatac tcaatgaaaa tcaaagagca
    45781 aactaggaaa ctagccgcag gctgctcaaa acactgtttt gaggttgtag ataggactga
    45841 cgaagtcagt cacatatata cggcaaggcg acgttgacgt ggtttgaatt tgattttcga
    45901 agaatataaa ctcatctgat aacaactatc ttaccccaat cactaaacaa aaactggact
    45961 tccttcccaa atgagcctat ctccctccca actgcacttt ttggataaaa aaataggcag
    46021 aacaagagtc ctgcccacta aaaatatgct attgaaagga aaatgatttt ttactgacac
    46081 cctaggcaag cttgaaacaa ataaatcatt gatagtaaca cttacgacat cctatttatt
    46141 acttcaattt ctaatgtctc tgctatttct aagctaccta tggtatgatc tatccctagt
    46201 cagaatagat aacaccgttc taaattacga ttcatagtta ctcctttttt gactcgttac
    46261 tataagactc ctctttacat gcgcaaaata attttgattc agattcatca tttatagttt
    46321 tgattatttt ttaacagatt tttctgtttt cttctccgaa gactttaaaa atttttttct
    46381 aattaaatca tccatataag gaccaaatat accaactact aaaccaataa taaaactttt
    46441 aaaatccata attaccacca acatgtcgct tcataggcca cacctccaag tatagctcct
    46501 cccgcagcac cagttgctgc accttgccat gttcttgttt taattcctag ctgaagacct
    46561 cgtgctactc ctcctccaac acctgctttg gcaaaatctc cccaattgca tccgccacct
    46621 tcaactcaag caagcatctc agtatccata atttcaaatt gtgacatctt ttttgtattc
    46681 ataacgaata cctctttttt atttttaata tttgtcttgt tacaaacttg acaagtttag
    46741 tataacagta tctattaatt tttttcatcc aaatcttgaa ttggcatcga aacgtcttga
    46801 attagctttt ttgtttcaaa atcatctcta tttttaaaaa agatgttttc taatcacttt
    46861 tttactatta gacttcctgc aaaactagaa tcctagttca tgattgataa taccagcaat
    46921 caaattcatt cgtaatccga agcgtttacg atgatttcga taggttgttg aaaacatttt
    46981 aaacgttttt actttggcaa agatattctc aaccttgctt ctctccttag atagcgcatg
    47041 attacaggct ttatcttcaa ctgttagcgg cttgagtttg ctggatttac gtggaagttt
    47101 gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaag attttaccag
    47161 cttgtccgat atttctcatt tctaaaaacc atctacttcc gttgacttgg aactccgatt
    47221 gctattttcc ttgaatgatt ttaaccacat ctcctacact ttggagttgg tcaatttcct
    47281 catcgctgat ttcgatacta aattcatcct ccagcgtcaa gataaactcc atcaaatcaa
    47341 ctgagtcagc atccaagtcg tctttcagac tcaaggattc tgtcacgaca aagtcctctc
    47401 cctgtcgctc ttggataatg gtcacaatac tgtcaaaaat ttctttttct ttcatctctt
    47461 ttattctcct gaaaattcac gcgcagtctg ggcaactact tctgtttcta gcatggtacg
    47521 aatctggcga atcgtactat aaacagcctt ggcatcgctt gagccatgag tcttgacaac
    47581 aggtgccttg acaccaaaca agaccgctcc accaacatct gaataattga gctgtttttt
    47641 caaacctctg aggctgtcct tgagaaggag ggcacctagt ttcgctcgaa gaccaccacc
    47701 tgtaatagct gtcttgagca agcccatgat tcccatagct gtcccttcga tggatttgag
    47761 cacagcgttt cccgtgaaac catctgccac aacaacatct gcaacaccat tcatcaaatc
    47821 acgcgcttcc acgtttccga taaagttcaa actttcatca gccgccagta attcataagt
    47881 ttccttacga agcgggtcgc ccttgctact ctctgttccg ttgttgagca aaccaacacg
    47941 tggttgcgca atgccacgaa cattcttggc atagaaagaa cctaggacag cgtattgatg
    48001 gaggtgctgg gctgtatttt ctgcattagc accgaggtca agcatgtcaa aacctttccc
    48061 atctacagtc ggcaatgttg acataagtcc aggacggtcg atattcttga tacgacccac
    48121 gatgaagaat ccagcagcca acaaagcacc tgtattccca gccgaaagga cagcgtctgc
    48181 ttcaccatct ttgacagcct tggctgccaa taccatactg gcatttttct tattccgaat
    48241 agctctcgta ggttcatcat ccgaatcaat cttctcatcc gtatggataa tgctgacgcg
    48301 ctctgtcgct gtcagatatt gcttgatttt agcttcatct ccgtagagtt gaacctcgat
    48361 atctgaaaag tcagataggg cttgattgac accctcaacg atggcctgag gtgcgtaatc
    48421 gccccccatg gcatctactg cgattttttt catttctttt cctcttttag taattgtccc
    48481 cagtctgcta gggaatcaat aaatttcttt gattttaggt gaatcccaac gtactcttca
    48541 tatagttgat ccataaattg gcgtagctct tgcttgattc caggcttgag cgaaatggtc
    48601 tccaaagtct caaaatcaat agcttgaaat tgattgagca gataggggat attgggattg
    48661 agatggcaac gtctctcatc ctcatgataa tgctctggac agagacaggc tccatatttg
    48721 aaagaaaagt caaaagcctg accaacccga tggcagaaga cacactcatt aaaattgagg
    48781 ctgattccaa atcgagtcaa aatttgaatt tcaaaaatat tggtcaaaac ctgataatcc
    48841 aagcctgctt ccatcaactc caaagtcttt tgcaaaaaag caaacaaggg agcatcctgc
    48901 tgattgtcct gcaaactagc atctgcaaga gctgccacat aggtcgcata ggccatgaca
    48961 aagaggtcac tattaatctt gggaaaagtc atgacctcat gatagtcttc gatgtaactg
    49021 agtccgtcat cattgattcg caagagaaat cgtgccagca ccaagggctg aataacaggc
    49081 gccagcttag actgaccagc gtgtttgaca aaaaacatgc atttgccaac ctgctctgta
    49141 aaaattttga caagcttgtc atcctcacga aaattgcgat tgtaaagcac caagccttga
    49201 ctcgtgatag actgaatcat gcttctctca tatactcctc aagtcgtttc atggcttctt
    49261 tgatagtctc catgctggct gcataagata ggcggacgta gccttccccg taacgtccaa
    49321 aggctgcacc agggataaag gcaacggcct tcttctgagc aaaatccttc agaaaagcaa
    49381 aggagtcttg attgtagccc gctggaattt tagcaaaaat atagaaggca ccgtctggtt
    49441 tgataatctc aaaaccaaga gcagtcattt tttcgatgat atagtcccga cgctggatat
    49501 attccttctt catgggctcc gcatcatttt taccagccgt caaggcttct accgcagcat
    49561 gttgcgccat ggtatttgcg gcagtgacca agtattggtg actcttgatt aactgggatg
    49621 tgaaggccgc aggagcgaaa atcagcccca aacgccaacc tgtcatggca tgcgatttag
    49681 acaaaccatt gataataata gcctggtctc tcaacatcgt tcctagagac acatgggctt
    49741 cgcctgtgta ggtcaattct gagtaaacct catcacagac aacaaaaatt tcgtacttgc
    49801 gtaaaacagc tgccaaggcc tctaactgct ctcgactgta ggtaattcct gtcggattgg
    49861 ctggatagtt gagaataacc gccttgagct tatcaccctg ctccaaaatg gccttctcca
    49921 acatctcagg agtcaagaca aaaccatttt cagtcgtatc aatctcaaca atttctgccc
    49981 caactaagtt aacaatcggt tcatagcctg gataagcagg agctggcaaa agtaccttgt
    50041 ctccctcttc caaaatagcc gtcaaagtcg cagataaagc ctctgtcgcc ccaattgtaa
    50101 ccaagatttc attttcagga gcatagtcca gttggtactt ttccttaaca aagtcactag
    50161 ctgcctgacg tagagtcagc agaccactca tccctgtata gtaggattgg ttctgatcaa
    50221 tcgctcgctt ggccgcctcc ttgacatggt ctggcgttgt aaaatcaggt tcccccaagg
    50281 tcaaacgcaa gaccccagga atctccgaaa tagcctggtc aaactgacga atcaacgaaa
    50341 cttgaatttt atctaactgt ttattaaagc gcttagttaa gtccatagat acctcctact
    50401 ttcaaaacgt atctctatta tactacaaaa gccccccgac cgcaaaaata cattagagga
    50461 tagctttcca ctttctattt tacttttcct gtttataggt ctataatggt aatagatttt
    50521 atttggaggt ttttatgtca tttctatcaa aaaatggagc aggtatcttg gcctgccttc
    50581 tcatttctat cgtatcttgg tacttaggag gattcttccc tgtgattggc gcgcccgttt
    50641 ttgccatttt cataggcatg ctcctacatc cctttctctc gtcctataaa caactggatg
    50701 ctggtttgac ctttagttcc aagaagttgc tccaatatgc cgttgtcttg cttggttttg
    50761 gtctcaatat ctcgcaggtc ttcgcagttg gccaatcttc actccctgtc atcctgtcca
    50821 ctatctcaat agctctgatt attgcctacc tcttccagcg tttctttgcc ctggatacaa
    50881 aactggctac cttggttgga gtaggttctt ctatctgtgg gggttctgcc attgcagcga
    50941 cagcgcccgt tattgatgct aaggaaaagg aagtagccca agccatttcc gttatctttt
    51001 tcttcaatgt cttggctgcg ctcatctttc caaccctcgg cacctggctt catctatcca
    51061 atgaaggctt cgccctcttt gcagggactg cggtcaacga cacttcctct gtaacggctg
    51121 ccgccagcgc ttgggacagt ctttaccaaa gcaataccct cgagtctgca accattgtta
    51181 aactcacacg tactttggcc attatcccta tcacgctctt tctatcctac tggcaaagtc
    51241 gccaacaaga aaacaagcaa agcctgcaac tgaaaaaagt cttcccactt tttatccttt
    51301 actttatcct tgcctctctc ctcactacac tactcacctc tctaggtgtg tccagtagtt
    51361 tctttactcc tctcaaagaa ctctctaaat tccttattgt catggccatg agtgctatcg
    51421 gtctcaaaac caatctggtc gctatggtca aatccagtgg aaaatccatt cttcttggag
    51481 ccatctgctg gattgccatc atcctcacca ctcttggtat gcagaccctt atcggcattt
    51541 tctaacactc ttcgaaaatc tcttcaaacc acgtcaacgt cgccttgccg tatatatgtt
    51601 actgacttcg tcagttctat ctgcaacctc aaaacggtgt tttgagcagc ccgcggctag
    51661 tttcctagtt tgctctttga ttttcattga gtataacaca aaaggtagcc catcagctac
    51721 ctttttctta tgcttcctca atcaagcgag tatgttctct cttgatacag cgattcatca
    51781 cgatatcatc acatccacca tcacgcaaaa tctctttcgc ttctaaactt tcaagtccta
    51841 gctgtgccca aaaaatcttg gcatcagctt tgagaaaatc acgcgccaca tcgggcagaa
    51901 attcactgcg acgataaaca ttgacaatat ctacaggaaa aggaatttca gcgaggctag
    51961 cataagcctt ttcacccaag atttcgccac ctgccgcctt gggattgact gggatgattt
    52021 tatagccccg agcctgcatt tcctttgtta ctcgattgct ggttgtttct tcacggtcag
    52081 acaaacccac cacagcaagg gttttactcg ttgcgagata ctgacgaatc acgccatcac
    52141 ttggattgat aaattcttga ctcatagaaa tcctcctttt tcatcagtat agcacatttt
    52201 gaaaaggttt gcagaattat actacaaaaa aggaggacta gccccctttt tatttagcct
    52261 cgtaccaggt tgccccttca ttctcatctg cgataagagg aacactgagt tgaatggctt
    52321 cttccatggt ttgtttcacc aattttttca tctctaccaa ttcagattta ggcacttcaa
    52381 ggacgatttc atcgtgcact tgtaacagca tcttagtctg ataaccacct gcaaccaagg
    52441 ctttatccag ctgaatcatg gcaatcttga gaatatctgc tgccgaaccc tggataggtg
    52501 agttgatagc agttcgttcc gcaaaaccac gaatattgaa gttgcgcgaa ttgatatctg
    52561 gcaactcacg gcgacgctta aagagggtct ctacatagcc cttatcacgc gcctcccgca
    52621 ccacttcatc catgtagttt ttaatacctg gaaaacgttc aaagtaggta tcaatgtagg
    52681 ctttggcttc cttacgacta attcccaaat tattagacaa gccaaagtct gaaatcccat
    52741 aaaccactcc aaagttaact gccttggcat tgcgacggtc gtttgcagtc acatcatcag
    52801 gacgctcaat gccaaagacc cgcatggctg tcgaagtatg gatatctgcc ccctcttgga
    52861 aggccttaat caagtgctca tccttagaaa tatgcgccaa aacgcgcaat tcaatctgtg
    52921 aatagtcaga gctgagtagc acactatcct cccactctgg cacaaaagcc ttccgaatca
    52981 agcgcccctg ttccaatcgg gcaggaatat tttgcaagtt tggatccaca ctagacaaac
    53041 gcccggtctg ggtcaaatcc tgcacatagc gagtatgaat ctttccatca gccaaaatcc
    53101 agtcctgcaa gccaattaca taagtagatt gaatcttagc aatttgacgg taatccagga
    53161 ttttcttaac aatcggagca ataggagcga gacgctccaa aacatccact gctgtcgaat
    53221 aacctgtctt ggttttctta gtgtattcta gaggaagtcc caatttctca aagagaagca
    53281 cgcccaactg cttaggcgag ttgacattaa actcctcacc agccagctcg taaatctctt
    53341 gagtcagttt ttcaatgaca agctcatttt cagcctgcat ctcaagcaag gtctctttct
    53401 tgaccataat cccagcaatt tccatcttgg caaggacaaa agccagaggt tgctccatat
    53461 cataaagaag ctctaattgc ccattttcgc tgagtttttc aagtaaaata ggctctgttt
    53521 ctaccaaaac agcaagttta caagctaagt gttccaagaa tttctcacgt tcaggaatgg
    53581 cctttttaac acccttaccg tagaaagttt catcatcaac caagtaagtc tgaccataaa
    53641 gactagcgat ggtcgcaatt tcattgtcct ccacagtcga aaggaggtat ttagccaaac
    53701 ggatgtcaaa agcaggcgcc tgcaaatcca caccaaaacg ttgcaaaaga actttaacct
    53761 tcttaaagtc ataaactctc agagatgttt tttctaagaa atccttgaaa atcgggtctt
    53821 gcaacagctc aagcttgtct gtggcataga gcttatcccc acaagaccag gcaaatccaa
    53881 ccaaattatc cgtatggtaa ttctcaccaa aaagctcaaa gtggaagata gactcttcac
    53941 tcagcatatc ttgactgatt tggtcaacaa tagtaaaatc caaactctca gacacatcag
    54001 ctgacgacac atttaaagcc tgctttagct gtttgaagcc catctcatcg tagaatttcc
    54061 caagattttc aacatctgga ccactataga ccaagtcctc taaaccaatc gcaatcggtg
    54121 ccttggtatc aatggtcgct agtgttttag acaaaaaggc ctgttccttg tcattgatga
    54181 gattttcctt catcttagaa gtcttcattc catcaatatt ttcataaatc ccctcaagcg
    54241 aaccatgctc cagcaagagc ttaatacccg tcttttcacc gactttggtc accccaggga
    54301 tattatccga cttatcaccc atgagcgcct tgagatcgat aaactgagct ggtgtgaggc
    54361 ccatttcttc catgaggtaa tctggcgtaa aggcctcaaa ctcagccaca cctttcttgg
    54421 aaatttcaac caccgtatgc tcatccgtca gctgaatcaa atccttgtcc ccactgacaa
    54481 tggtaatatc aaaaccatcc tgctctgcta gcttatccag cgtcccaatg atgtcatccg
    54541 cctcatactg agccagctca tagtgacgaa tccccatatg atccagcaac tcacgaatga
    54601 aaggaaattg ctcacgaaac tcatcaggag tcttggcccg accaccctta tagtccgcat
    54661 acatctctgt ccggaaggtc gtctttcccg catcaaaagc caccaaaata tgactcggct
    54721 caacccgctc caacaaatga ctcaacatca actgaaaacc ataaatcgca ttggtatgca
    54781 aaccagccgc attcttaaaa cggtccaact gctgatacag cgcaaaaaac gcccgaaaag
    54841 ctacagaaga cccatcaatc aataataatt ttttcttatc catacaccca ttataaagga
    54901 aagaatcaaa aaataccatt gggaagagct agagcaagta tttttcaaac tttttccgaa
    54961 taaatagata gagccagaga atttagtaaa cctagattta aaaatgtgct ataatatagt
    55021 atattgaatc tataatagta caccttgact gctaaaatat ttctataaat taatttgact
    55081 ttcctgatag agttattcac atcttatttc aactcactat agaaggagga ataggaggat
    55141 tctcagacat ccgggcatca gcccaactaa tgatttgatt gctaagaaaa tattcagcaa
    55201 tccagaaatc acttgtcaat ttattcgcga tatgctggac ttgccagcaa aaaatgtgac
    55261 cattttggag ggaagcgata ttcacgtatt actctccatg ccttactcgg tgcaggattt
    55321 ttataccagt atagacgtct tggcggagtt ggataacggt actcaagtaa ttattgagat
    55381 tcaagtccat catcagaatt ttttcatcaa tcacttgtgg gcttacctgt gcagtcaggt
    55441 taatcaaaat cttgaaaaaa ttcgtcagcg agaaggtgat actcactaga tctacaaaca
    55501 catcgctcct gtttacgtca ttgctatcgt ggatagtaat tatttctcag atgacctggc
    55561 ttttcatagc tttagtatgc gcgaagacac aacaggtgag gtattggcga ttaccaacaa
    55621 tggacaggaa aaccatctgg ttaagatggc attcttggaa ttaaaaaata cagagaaacc
    55681 agcaaagaca aggttcgcaa gccatggttg gagtttttcg gcaacaagcc ctttacccag
    55741 caaccgcaac gagccattac ccaagcaaat caactgctgg actacaagag ctggtccgag
    55801 gaggacagga aaatgtttag tcaactacat atgcgagaag aacaagtctt gttagcacag
    55861 gactatgcct tggaaactgc tagggctgaa ggccttgaac aaggactaga gcgtgggaaa
    55921 gttgaaggaa gggcagaaag gaaacttttt gccttcctag acatagtacg ccaaggtctt
    55981 ctgacttctg aggttgccag ccagcaatta ggtatgtcag tatctgaatt tgaggcactg
    56041 ttgtaaaatg gctccataat atccataggg gatttaccca ctatggatat tatggagcct
    56101 attttgtgta aaaaaaagtc ccatatgacc tataatgaaa agcgacaaaa caactcatta
    56161 gaaagaatca tatggaacaa ttacatttta tcacaaaatt actagacatt aaagacccta
    56221 atgtccagat tttaaacatc atcaataagg atacacacaa ggaaatcatc gccaaactgg
    56281 actacgacgc cccatcttgc cctgagtgcg gaaaccaatt gaagaaatat gactttcaaa
    56341 aaccttctaa aattccttat cttgaaacga ctggtatacc tactagaatt ctccttagaa
    56401 agcgtcgatt caagtgctat cactgttcaa aaatgatggt cgctgaaact tctgatgacg
    56461 tacagtcata tttcttctct ttttattata tcacagtttt aaatctagct ttactagatt
    56521 caccgctact atctatttat tcggaaaaaa gacgaaaaaa cctgagaatc atctcaggct
    56581 tggtcattaa atttttttct caatatcgaa aagtggagaa agtggtcgtt tttcatgaat
    56641 acgtacgata gcatccccta ggagatgagc gattgaaatc tgctcaatct tatcaatcaa
    56701 acgctcttct ggcagataga tggtatccaa aacaaccaat ttcttaatag ctgatttttg
    56761 gatattgtcc gtagcaggac cagaaagaac tgggtgcgta cagcttgcat agacttcaac
    56821 agcaccagct tccgcaagag catctgccgc atgacaaatc gttccagcgg tatcaatcat
    56881 atcatcaatc aagatacaag tcttgccttc aaccttaccg atgatgttca taacttcact
    56941 agtattcatc ttatcaacgc tacgacgttt atcaataata gcgatagatg ttttcaaaaa
    57001 ttctgccaac ttacgagcac gagtcacccc tccatggtcc gggctgacaa ccacatagtc
    57061 agaaccaacc ataccacgac gctcaaaata atctgcaatc agaggagcac ccatcaaatg
    57121 atccacagga atatcaaaga atccttgaat ttgcgcagca tgcaagtcga tggtcaataa
    57181 acgatccact ccagctactt caagcatatt tgcgacaagt tttgaagtga ttggctcacg
    57241 cgctctcgcc tttctatcct gacgtgcata cccatagtaa ggcatgacaa cattaacaga
    57301 ttctgcactc gcacgcttca aagcatctac cataatcaaa atttcaagca gattgtcatt
    57361 tacaggcgaa ctagttgatt gtaagataaa gacgtgtttc ccacggattg attcttcaat
    57421 gttgacctga atctctccat ctgaaaattg gcgaacactt gatttcccca actctatccc
    57481 aatctcctgc gccacacgtt ctgccaattc tttattagaa gaaagggcaa acagctttaa
    57541 atcagaaaaa gacatgattt cctccggtat atatgtataa cttgtgcttt tcacaagatt
    57601 ttccatctac cattgtagcg ctttttgcac tatttttcaa tcaaaaataa aagaagggca
    57661 ccatatttgt acccttgcat cattcttttg aaaaatattc taggtcatca actcattgtg
    57721 tttctcaaca aagcaataag catgataaaa accatagaga gcaatagccg taaccactgg
    57781 aatcgctaaa ggcaactctg tttccaactc cacaaaagga gagttaaaca agaagtgagt
    57841 tcccaaggct aaacctagaa aaataagtcc ctgtttcttg ccaaccttct gtcctttata
    57901 ggctctgtaa agcaagtaaa cacctactac agctagacct gaaaaagtcc agtgagaggc
    57961 aattcctgag atgatacgct ctaaaattcg cgaaatagta aagtcaaagc cctctggcaa
    58021 atccgtacga atataaccaa tatcctcaat catttggaat cccaaaccgg aagcaattcc
    58081 aagtaaaaac aaagatttta attttcgcac aggaatcaaa gccaaaacaa aaacaagtgg
    58141 caataatttc aagggttctt ctaccaaagg agccacaata gcactttcaa aggcatttaa
    58201 aaatgtacta tctgggaaaa gaacccccag taaatcatgg atataagtat tagcaaaact
    58261 agacaaccat cctgaaagga acatccctcc caataaagac agaatcaaaa ccttctttgg
    58321 caattcccat ttttcccaat acggaagaga aaataaagag ccggaatcat gtaaaagaga
    58381 gctagaaaga tagaaattcc cattagtcca tattccgcac ctgacctcga accgtccgta
    58441 tagtagatgg tttcatactg taaaccaata catagcaata aaataaaaat aaataaaata
    58501 ctgcttttct tcatacactt tctttctaaa tgaagtattt ataattctac gactgtcata
    58561 cttcctgtat caacattgta aatagcacca gagataatga catcgtctgg tattagggga
    58621 gactcgataa gcagttgcat atcctcgcgt acactctctt ctatatcttg gaagggcaag
    58681 aagtcctggt ctgacacatc tacacctaat tcctctttta aatactcctg aaaaggttca
    58741 ttttcaaagg tctgagcacc acagtctgta tggtgcaata ccacaatctc tcttgtcccc
    58801 atttgttgct gggaaataac tagcgaacga atcatgtctt cagtcactcg accacctgca
    58861 ttccgcaaga tatgagcatc cccaagtgcc aagcccagag cttgcgcaac gtgcagacga
    58921 gagtccatac aggtcacaat agctactctt gttttgggtt taagtggcag atttaactgc
    58981 ccatgtaggg caacataagc ctgattggct tgcataaact gttcaaaata cgacacgatt
    59041 ccctccttga aaatttgata gtcaaatatt tctcctatct tatcattttt aagagaattt
    59101 gtcacggatt atgcaaagac ctttttcaaa acttcctgaa tcgttgtcac gccaatgacc
    59161 tgaatttcct taggcagagt gattcctgtc aaggaattct taggtacata aatcttagta
    59221 aagcccagtt tagcagcttc gttgatgcgt tgctcaatac gattcacgcg ccgaatctct
    59281 cctgtcaagc ccagttctcc gacaaaacat tcctgaggat tagttggttt gtctttgtag
    59341 ctcgaagcaa tagcaactgc aacagccaag tcaatggcag gttcatccaa tttaacacca
    59401 ccagcagatt tgagataggc atcctgattt tgcaagagaa gccctgcccg tttttccaaa
    59461 acagccataa tcaagctagc acggttaaaa tcaagtcctg tcgtagtacg cttggcattt
    59521 ccaaacatgg tcggtgttac taaagcctga acctccgcca aaatcggacg cgtcccttcc
    59581 atggttacaa cgatggagga accagtcgcc ccatccaaac gctcttctag gaaaacttga
    59641 ctcggattga gtacctcaac caagccgccc gactgcatct caaaaatccc aatctcatta
    59701 gtggaaccaa aacgattttt gaccgctctc aaaatacgaa aggtgtggtg acgctcccct
    59761 tcaaagtaaa gcaccgtatc caccatatgc tccaacatac gaggcccagc caaggttcct
    59821 tctttggtca catgacctac gataaagatg gcaatgttat tggtcttggc caactgcatg
    59881 agttcagcgg tcacttcacg tacctgagaa acagacccct gcacccctga aatctcagga
    59941 gacatgatgg tctggatgga atcaataata agaaagtctg gctggatacg ctccacttct
    60001 gcacgaacac tctgcatatt ggtctctgca tagagataaa actcactatc aatatcacct
    60061 aagcgctctg cacgtagttt aatctgctgg gcagactcct ccccactgac atagagaact
    60121 gtccccactt gggacaactg ggttgagact tgttggagaa gagttgattt cccaatccca
    60181 ggatccccac cgatgaggac gagacttcct ggtaccactc cgcctccaag cacacggttg
    60241 aattcctcca tctccgtctt ggttcgattg acattgatgg aagtcacctc agctagtttc
    60301 atgggcttgg ttttctcacc tgtcaaggac acacgcgcat tcttgacctc ggcaacctca
    60361 acctcttcca caaaagaaga ccaagatcca cagttggggc aacgtcccag atatttaggg
    60421 gaattatacc cacaattttg acatacaaat gtcgcttttt tctttgcgat gacaaacctc
    60481 ttcctatatc tctaactcac actcaatcac ttggcaaaaa tcaatcttct catttggcac
    60541 aaactggcgc atgagcattc gatgagcaac aactaccaca gtctgatgtt ctcgatactt
    60601 agacatacat tctagaaacc gagacttcat ttccgtagct gtctcatatt gaataggact
    60661 attaggaagc aactccccct tgttttctaa aaacagtctt ctagctgttt caaagttttc
    60721 tattcctgtt ttatagacct gccattcatg taataaaggc tctactctta aaggaagacc
    60781 cgtagcacag accacatacg aagccgtttc taaagctctt gtgactgcag aagatacgat
    60841 tatttcagct gacgagagta aaggattttt gctcaatttc tggacttgct gccgtcccat
    60901 ctcagacaag ggtgccaaat ctatcccaaa tcctatataa gaacgctcct ctaactcacg
    60961 gtaatctggc tccccatgac gtacaaagat aatcttcatt ctagtgccct gtcgatccaa
    61021 atccaccagt tcgaacgcca ccagctgcat ctccatctgc aattaagaaa gtagcaaaaa
    61081 cagcctggac aatacgttcc ccaacttcaa gaacaacctc ttggtctgtg atattcttca
    61141 tctgcgcaaa aatatgccct tcatttccag gatttccata ataatcccca tcaatgaccc
    61201 caactgagtt aattaaaacc aagcccttct tacgaggatt tgaagaacga tcatagaggt
    61261 agagaacctc agtcggctgc atataagcct taacccctgt cggaaccaag acaatctctc
    61321 ctggcgcaac aactgtacgc acagcaacct ttaagtcgta accagccgca tgcgctgtct
    61381 cacgcttggg caataaattt tcatctgtaa aacttgaaac caattcaaaa ccacgaattt
    61441 tcataatttt ctcttttcta ttatcattta ttctagatta ttctatctta tttattcgga
    61501 aaaagcacga aaaaagagca cacaattcaa atcgcttagg gctgctggat tcctcccctg
    61561 acccgcttca cgcagaactg ttgctccact atttattata tcacattcct attcatttta
    61621 aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag ctgcgcattc
    61681 atcttccaaa attcctattt caacctccac acgatgattg agacgctcat ctgtcaagat
    61741 attgtacaaa ctcccagcag cgccaaattt ctggttttta gccccataga ccacatttgg
    61801 aatgcgggca agcccaatcg ctccactaca catgacacaa ggttcaatgg tcacaaaaag
    61861 tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta tagccataat
    61921 ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac gaccaatgat
    61981 ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa gagcaatctc
    62041 agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat aatacatctc
    62101 ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac acaaaaaaag
    62161 ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt taggatattt
    62221 gttacaacaa gttaggaggt cttcttgtaa ccgtctatag tatacccgac ctatcttaaa
    62281 caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg ttcacgacca
    62341 ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg acgaacatag
    62401 ttacgcgcat tctcaggaag atcttccaaa ttgcgaactc cggtaatatc ttctgaccaa
    62461 cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact agctggatag
    62521 tagtcaatac gttgaccgtc aagatcatag gccacacaga ttttcacagt atccaaaccg
    62581 ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg acggctatga
    62641 cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt tgtaccatac
    62701 tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt tgggaaagga
    62761 ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc aatcttgctt
    62821 ggaccgacac cagaaccaat tgtcacacca ccagctacag ggtttgatga cgtaacaaat
    62881 ggataagtac cttggtcgat atctagcata acaccttgtg caccttcaaa aagcacacgt
    62941 ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta tttcttgatt
    63001 tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc tttactgtca
    63061 tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg ctcacggaaa
    63121 atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt gtccatataa
    63181 gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc ttcttcttgc
    63241 aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga aatacgcaag
    63301 ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag agatttagga
    63361 tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat cccagatgga
    63421 atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc attatcacca
    63481 ccttggtaac gtgcaatcac ttctgcattc gctgaaagga agtctgtaat cttcccttta
    63541 ccttcatcac cccattgggt acctacaaca acaactgaag tcataatctt gtctgagccc
    63601 tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat atcttacaat
    63661 ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat ttgctatttc
    63721 caactattaa aaaatgattt agaaaaatta ctagctattt actatcatct ttccataaaa
    63781 gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa ccccgattca
    63841 ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg ataaaatccc
    63901 tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa tgaacatgtt
    63961 cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta tcatagaaat
    64021 tagccatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct tttttataaa
    64081 cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt aaaataccag
    64141 gctcaacaag ataaaaatag gaaaagttga cagaatagaa acaaatttgc tacctaaatt
    64201 tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggta
//
LOCUS       DBERDS010000007        52877 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.007, whole genome shotgun sequence.
ACCESSION   DBERDS010000007 DBERDS010000000
VERSION     DBERDS010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 52877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.007"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..618)
                     /locus_tag="ACL73E_000499"
                     /pseudo
     CDS             complement(1..618)
                     /locus_tag="ACL73E_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            complement(1002..2198)
                     /gene="tuf"
                     /locus_tag="ACL73E_000500"
     CDS             complement(1002..2198)
                     /gene="tuf"
                     /locus_tag="ACL73E_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS0800525.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(3109..3978)
                     /gene="gla"
                     /locus_tag="ACL73E_000501"
     CDS             complement(3109..3978)
                     /gene="gla"
                     /locus_tag="ACL73E_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGS0800526.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(4201..4722)
                     /locus_tag="ACL73E_000502"
     CDS             complement(4201..4722)
                     /locus_tag="ACL73E_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS0800527.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4680..5786)
                     /locus_tag="ACL73E_000503"
     CDS             complement(4680..5786)
                     /locus_tag="ACL73E_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGS0800528.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5897..6151)
                     /locus_tag="ACL73E_000504"
     CDS             complement(5897..6151)
                     /locus_tag="ACL73E_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800529.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6145..6387)
                     /locus_tag="ACL73E_000505"
     CDS             complement(6145..6387)
                     /locus_tag="ACL73E_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800530.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(6509..7042)
                     /locus_tag="ACL73E_000506"
     CDS             complement(6509..7042)
                     /locus_tag="ACL73E_000506"
                     /inference="COORDINATES: protein motif:HMM:NF024751.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGS0800531.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(7029..7355)
                     /locus_tag="ACL73E_000507"
     CDS             complement(7029..7355)
                     /locus_tag="ACL73E_000507"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS0800532.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7589..9307
                     /locus_tag="ACL73E_000508"
     CDS             7589..9307
                     /locus_tag="ACL73E_000508"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGS0800533.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAILVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9418..9765
                     /locus_tag="ACL73E_000509"
     CDS             9418..9765
                     /locus_tag="ACL73E_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGS0800534.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(10043..10879)
                     /locus_tag="ACL73E_000510"
     CDS             complement(10043..10879)
                     /locus_tag="ACL73E_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0800535.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10892..11521)
                     /locus_tag="ACL73E_000511"
     CDS             complement(10892..11521)
                     /locus_tag="ACL73E_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0800536.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11531..12172)
                     /locus_tag="ACL73E_000512"
     CDS             complement(11531..12172)
                     /locus_tag="ACL73E_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0800537.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12318..13547)
                     /locus_tag="ACL73E_000513"
     CDS             complement(12318..13547)
                     /locus_tag="ACL73E_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGS0800538.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13537..14703)
                     /locus_tag="ACL73E_000514"
     CDS             complement(13537..14703)
                     /locus_tag="ACL73E_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGS0800539.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14847..15860
                     /locus_tag="ACL73E_000515"
     CDS             14847..15860
                     /locus_tag="ACL73E_000515"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGS0800540.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15905..16324)
                     /locus_tag="ACL73E_000516"
     CDS             complement(15905..16324)
                     /locus_tag="ACL73E_000516"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGS0800541.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16335..17741)
                     /gene="atpD"
                     /locus_tag="ACL73E_000517"
     CDS             complement(16335..17741)
                     /gene="atpD"
                     /locus_tag="ACL73E_000517"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGS0800542.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17827..18705)
                     /locus_tag="ACL73E_000518"
     CDS             complement(17827..18705)
                     /locus_tag="ACL73E_000518"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGS0800543.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18721..20226)
                     /gene="atpA"
                     /locus_tag="ACL73E_000519"
     CDS             complement(18721..20226)
                     /gene="atpA"
                     /locus_tag="ACL73E_000519"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGS0800544.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(20241..20777)
                     /locus_tag="ACL73E_000520"
     CDS             complement(20241..20777)
                     /locus_tag="ACL73E_000520"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGS0800545.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20777..21271)
                     /gene="atpF"
                     /locus_tag="ACL73E_000521"
     CDS             complement(20777..21271)
                     /gene="atpF"
                     /locus_tag="ACL73E_000521"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGS0800546.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21285..22001)
                     /gene="atpB"
                     /locus_tag="ACL73E_000522"
     CDS             complement(21285..22001)
                     /gene="atpB"
                     /locus_tag="ACL73E_000522"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGS0800547.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(22036..22236)
                     /locus_tag="ACL73E_000523"
     CDS             complement(22036..22236)
                     /locus_tag="ACL73E_000523"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGS0800548.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(22311..23246)
                     /locus_tag="ACL73E_000524"
                     /pseudo
     CDS             complement(22311..23246)
                     /locus_tag="ACL73E_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23695..24093)
                     /locus_tag="ACL73E_000525"
     CDS             complement(23695..24093)
                     /locus_tag="ACL73E_000525"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0800549.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(24466..24948)
                     /gene="greA"
                     /locus_tag="ACL73E_000526"
     CDS             complement(24466..24948)
                     /gene="greA"
                     /locus_tag="ACL73E_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGS0800550.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(25019..26674)
                     /gene="mltG"
                     /locus_tag="ACL73E_000527"
     CDS             complement(25019..26674)
                     /gene="mltG"
                     /locus_tag="ACL73E_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGS0800551.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(26755..27249)
                     /locus_tag="ACL73E_000528"
     CDS             complement(26755..27249)
                     /locus_tag="ACL73E_000528"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0800552.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(27246..27710)
                     /locus_tag="ACL73E_000529"
     CDS             complement(27246..27710)
                     /locus_tag="ACL73E_000529"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0800553.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDCKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(27720..29054)
                     /gene="murC"
                     /locus_tag="ACL73E_000530"
     CDS             complement(27720..29054)
                     /gene="murC"
                     /locus_tag="ACL73E_000530"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGS0800554.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(29065..29682)
                     /locus_tag="ACL73E_000531"
     CDS             complement(29065..29682)
                     /locus_tag="ACL73E_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS0800555.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(29730..32828)
                     /locus_tag="ACL73E_000532"
     CDS             complement(29730..32828)
                     /locus_tag="ACL73E_000532"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0800556.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQVLVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(32921..34087)
                     /locus_tag="ACL73E_000533"
     CDS             complement(32921..34087)
                     /locus_tag="ACL73E_000533"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGS0800557.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQIYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(34095..35189)
                     /locus_tag="ACL73E_000534"
     CDS             complement(34095..35189)
                     /locus_tag="ACL73E_000534"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGS0800558.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(35346..35933)
                     /locus_tag="ACL73E_000535"
     CDS             complement(35346..35933)
                     /locus_tag="ACL73E_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0800559.1"
                     /translation="MLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSG
                     SIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRL
                     QIARTYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDC
                     IFFLEEGKITGSGTHKELLENHERYACFVQEQMIE"
     gene            complement(35927..36840)
                     /locus_tag="ACL73E_000536"
                     /pseudo
     CDS             complement(35927..36840)
                     /locus_tag="ACL73E_000536"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(36809..37009)
                     /locus_tag="ACL73E_000537"
     CDS             complement(36809..37009)
                     /locus_tag="ACL73E_000537"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800560.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSYWSSLVFFYWLLSV"
     gene            complement(37181..39139)
                     /locus_tag="ACL73E_000538"
     CDS             complement(37181..39139)
                     /locus_tag="ACL73E_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0800561.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     AYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(39342..40964)
                     /locus_tag="ACL73E_000539"
     CDS             complement(39342..40964)
                     /locus_tag="ACL73E_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGS0800562.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            41070..42515
                     /locus_tag="ACL73E_000540"
     CDS             41070..42515
                     /locus_tag="ACL73E_000540"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGS0800563.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLREQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISNYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(42558..42755)
                     /locus_tag="ACL73E_000541"
     CDS             complement(42558..42755)
                     /locus_tag="ACL73E_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS0800564.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(42856..43505)
                     /locus_tag="ACL73E_000542"
                     /pseudo
     CDS             complement(42856..43505)
                     /locus_tag="ACL73E_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(43489..44001)
                     /locus_tag="ACL73E_000543"
     CDS             complement(43489..44001)
                     /locus_tag="ACL73E_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGS0800565.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(44087..45022)
                     /locus_tag="ACL73E_000544"
     CDS             complement(44087..45022)
                     /locus_tag="ACL73E_000544"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGS0800566.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(45093..45392)
                     /locus_tag="ACL73E_000545"
     CDS             complement(45093..45392)
                     /locus_tag="ACL73E_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGS0800567.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGRGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(45382..46131)
                     /locus_tag="ACL73E_000546"
     CDS             complement(45382..46131)
                     /locus_tag="ACL73E_000546"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGS0800568.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(46185..46544)
                     /locus_tag="ACL73E_000547"
     CDS             complement(46185..46544)
                     /locus_tag="ACL73E_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGS0800569.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(46546..47946)
                     /locus_tag="ACL73E_000548"
     CDS             complement(46546..47946)
                     /locus_tag="ACL73E_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGS0800570.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILIGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(48241..48480)
                     /gene="rpsR"
                     /locus_tag="ACL73E_000549"
     CDS             complement(48241..48480)
                     /gene="rpsR"
                     /locus_tag="ACL73E_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGS0800571.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(48512..48982)
                     /gene="ssbA"
                     /locus_tag="ACL73E_000550"
     CDS             complement(48512..48982)
                     /gene="ssbA"
                     /locus_tag="ACL73E_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGS0800572.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(48994..49284)
                     /gene="rpsF"
                     /locus_tag="ACL73E_000551"
     CDS             complement(48994..49284)
                     /gene="rpsF"
                     /locus_tag="ACL73E_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGS0800573.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(49437..50783)
                     /gene="asnS"
                     /locus_tag="ACL73E_000552"
     CDS             complement(49437..50783)
                     /gene="asnS"
                     /locus_tag="ACL73E_000552"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGS0800574.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(50799..51164)
                     /locus_tag="ACL73E_000553"
     CDS             complement(50799..51164)
                     /locus_tag="ACL73E_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0800575.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(51157..52344)
                     /locus_tag="ACL73E_000554"
     CDS             complement(51157..52344)
                     /locus_tag="ACL73E_000554"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0800576.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(52341..52829)
                     /locus_tag="ACL73E_000555"
     CDS             complement(52341..52829)
                     /locus_tag="ACL73E_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGS0800577.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEKADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
BASE COUNT        15464 a        11647 c         9729 g        16037 t
ORIGIN      
        1 atgtggacct actcctattg gagcccaaca agatcccagt ttactgattc taccgaaacc
       61 agcctcatct tggtacatca agcgaacctt acgaaaacgt ctactatatt taaaacgctt
      121 tcttgtcttc ttgaattgag attttatttt tagacgcgac aatggtttga gcgtctgctt
      181 tcttaggatg ttctggacgt ggcataatat ttcgccaacc atggcgcttc aacagttgat
      241 agaaggcatc acgtgtgtag gaacgaccta actccttttt ataagcctga aataaggcat
      301 caattgtaac aaattctcct gcctctgcag ccttcaaatg gcgggcaaga aagactttct
      361 cttcctcaac tgtcatatat gcatggttac gaccaccacg tgtttcttga aggagagagt
      421 cgagtccgaa ctcctcatat ttttttacat ttcgccaaat cattgtttga ttacagtcta
      481 aaagttctat aatctcttta taagatttgc ccatatcaga cgaaatagaa cgatttgaag
      541 acgtttatga tatttagctg tacgagagtc ttttaaaagt gttttgatgg tttggatttc
      601 ttctttaatt gatttcatat tactattgta taatgctttt tgattttagt ctagtattat
      661 actcttcgaa aatctcttca aaccgcgtca gcttcgcctt gtcgtataga tgttactgac
      721 ttcgtcagtt ctatctacaa cctaaaaaca gtgttttgag cagtctgtag ctaactttct
      781 atagtaaaat gaaataagaa caagacaaat cgatcaggac agtcaaatcg atttctaaca
      841 atgttttaga agtaaatgtg tactattcta gtttcaatat attatagttt gctctttgat
      901 tttcattgag tattagttca atatctaaaa aaagaacctt gccaagcaag attcttttag
      961 tgtctgactt aaataattgt tcttctggga actaaatcga attaagcttc gatttctgta
     1021 accatacctg aaccaacagt acgtccaccc tcacggatag agaatgtagt accttgttct
     1081 acggcgattg ggtgaatcaa ctcaacgtcg attgtcacgt tatcaccagg cattaccatt
     1141 tcagtacctg ctggaagttc gattgaacct gtaacgtcag tagtacggaa gtagaattgt
     1201 ggacggtagt tgttgaagaa tggagtgtga cgtccacctt cttctttagt aaggatgtag
     1261 acttcacctt tgaatttagt gtgtgggttg attgaacctg gtttagcgat aacttgtcca
     1321 cgttcgattt catcacgttg aacaccacga agaaggacac ctacgttatc tccagcaaga
     1381 ccttcgtcaa gttgtttacg gaacatttca acaccagtaa caactgcttt ttgagtttct
     1441 tctttgatac caacgatttc gatttcgtcg ttgactttaa cgataccacg gtcgatacgt
     1501 cctgaagcaa ctgtaccacg tccagtgatt gagaatacgt cctcgactgg aagaagcaat
     1561 ggtttgtcag tgtcacgttc tggttctggg atatactcat caactgtgtt catcaattcc
     1621 ataacgatgt cttcgtattt agagtcacct tcaagagctt taagtgctga accttggata
     1681 actggaagat cgtcacctgg gaagtcgtat tctgacaata ggtcacggat ttccatttca
     1741 accaattcaa gcaattcttc gtcgtcaacc aagtcaactt tgttcatgaa gacgataagg
     1801 tgtttaacac caacctgacg tgaaagaagg atgtgctcac gagtttgtgg cattggtccg
     1861 tcagttgaag ctactacaag gatagctccg tccatttgag cagcaccagt gatcatgttt
     1921 ttaacgtagt ccgcgtgtcc tggagcgtcg atgtgagcgt agtgacgttt ttcagtttcg
     1981 tactcaacgt gcgcagtgtt gatagtgata ccgcgttcgc gttcttctgg agcagcatcg
     2041 atagacgcat agtctttagg ttggttaact gatgaaggca agcgacgtgc caaaacagtt
     2101 gtgatagctg cagttagggt agttttaccg tggtcaacgt gtccgatagt accaatgtta
     2161 acgtgtggtt tactacgatc gtatttttct tttgccattt gagtaaaagc ctccaataaa
     2221 atatatttta tagatagaca gtaggcaata cagtctaact ttccttacta ttttatcaaa
     2281 tttcagctaa attgcaagtg ttttacaacg tttttgtgaa ttattcttga taaaaattta
     2341 actaactaat agaaagtact aaatagactt atccttcaag gagttttcag cattatccat
     2401 ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg aaacaagaat
     2461 agggcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gttgaggtgt
     2521 actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca acctgcggct
     2581 agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa aacgataaca
     2641 atcataggac tcagcagagt caatgtaggt cgaagaatag ccctcctaat cgcttatttt
     2701 atagcaaaat gaaatagaaa ctgaacattt tgttgaggaa ggtaaatcaa ttcctcacaa
     2761 tgtttgagaa agaagggagg actattccaa cttcaaccca ctataaagca gacttacaag
     2821 atagggaacc catctccgat aatatatagt agaatgaaaa ctgcacaatt tgattggaga
     2881 attcaaacca atttctaaca atgttttaga aacaagggtc tattatttca actgcaacct
     2941 actatagccc attgaagctg gaatagccca ctgagacttc taaaccactg ctggagagga
     3001 gtttgtttag agtttctttc atttccctaa aaaatcaaaa agagagaacc agtctgatcc
     3061 tctcttactt atagatggtg ctcactcaaa tgttaaagga gctatttctt agagataaag
     3121 gaatttgaat acagctactg ccgcaattgc tgctgcgata ggtgctacta ctggtaccca
     3181 agaataccac cattttgaat cgcctttatg ctcaccaaga actgattttg gaaggaaagc
     3241 atgaaggaga cgtggtccca agtcacgggc tgggttcaag gcaggtcctg taggtcctcc
     3301 aagtgatgtt accaaagcca taacgaggaa tccaagtgcc aagtgagcca cagaaagtcc
     3361 tgaagcagtg tgtggagcca cctgtgcttt aatagccaag tcagaaaaat caactgtttg
     3421 tcctgcttct attgcctttt gtttcatgaa ttgaagcact tcagcaccaa agaagttttt
     3481 agtcaaacca agagctgcaa agaacaaaac aaatgaacca acaaactcat taatcaaacc
     3541 attgacagtt gctgcatagc gactttcttt tgtaccatgg tcaatacttg aaatagttga
     3601 gaaagttccc aagatgttat ttggtttttc agttttcaag tagaatggac ggtatgttgc
     3661 cacaactaag gcttggccaa agatagcccc caagacttgc gcgataatgt aaggtaccac
     3721 ttgtgcccaa gggaaaagac cgctaactgc aagccctaga gtgaaagcag ggttgatgtg
     3781 attcccagat acgttaccaa acatcaaggc tgggatcata acccccatac cataaccaac
     3841 agcgatgacg atccagccac tttggtgacc tttcgtacct ttaagttcaa cgttggcaac
     3901 tgcaccattc ccaagaatga tcaaaatggc agttcccaaa aattcagtgg catacttcag
     3961 tgcccatgtg aaatccattt gctagattct ccttaaaatt ttttagatat tccttatttt
     4021 atcaattttt accctattta gcaactgatt tctggaaata tttttaaaaa aataggattc
     4081 atagtttccc agttcaacgt acttgtaagc gtttttattc ttcacgaaag acctcattct
     4141 caaaaccagg aaaaagccca catctgtgat cttttccttg ttcctagatt ctaaaatcta
     4201 ttatttttca tcttcttttt tcttgaagaa tcctaatcct agaccagcta acaaggtcat
     4261 gataccagca ctagccaagg tagcattagc ttctgtacct gtgtttggca attcctctct
     4321 cttacctgtc tcataagtcg gaacttctgg gtctggattc actggagttt cagtttttgg
     4381 agtacctggg tctggagttg gtttatctgg tgttgataaa cggtcatacc ttaccgttat
     4441 ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa tatctggatc
     4501 tttgtacttg tcaatcttac cagatacaac ctcgtcccag tttcctgttg tccattcacc
     4561 gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg ttacaggttg
     4621 aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa tgatacgcgt
     4681 tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct caacattctc
     4741 acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg agttgctacc
     4801 aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt tgttgttttc
     4861 ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc agcttttata
     4921 acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt tactgtagca
     4981 gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc gcttacaata
     5041 ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata ttttccgtca
     5101 gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc aatcagttgt
     5161 tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt atcatttttc
     5221 aatgatagca aacgcccttg ttcatcaaca tagcgaactt tcacattttc tgagattagt
     5281 tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt ccctttctct
     5341 tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga tggttccaca
     5401 gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac acggtgactt
     5461 tgagtgttta ctcctactct ttcattattc tctgaaaata cttgtacggt ataagaaaca
     5521 acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc tagtttgcta
     5581 tctccagagt ccacttcttt cctaatctta tcagatagtt ttttaccagt cagtacattc
     5641 gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa ctcttcagaa
     5701 ccagatctag cccaaccatt attaagggca tttgcttttg tatttgtatt ctctctcaaa
     5761 ggtttggcga ttagaattat attcatcggc acttagagtt gctgctatat ctgactcttg
     5821 aataccaact tccttactac catttctagc ggcagtatat gtgtatttat ctgtttctac
     5881 ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga gtcttcagta
     5941 gtttatatgc tctgtcatca tctttagctt tagaagcagc tgagtttagc caagttgggg
     6001 tattaggagt atctttatca gcctgtttca agacattatt caagtcattt gctaacctat
     6061 tggttgtcct cactgtgaaa gttttcttcc agtctgaatc acttttatta gacttagata
     6121 tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta gcatcttccg
     6181 ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag tttttttatt
     6241 tacacgattt aatgtactat tttttatttt agtattaaga actccattaa tacgattttt
     6301 aaattctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat tcaaaccttt
     6361 cttatacaag tcttcattct gatacaagtc ttcattctga acgatttcgg ctacacggtg
     6421 aatggtttga tcgtataccg tcttctctta accagcagta tccttagttt taatgactac
     6481 tcgataggtt cctttagaac cgttatagtc atctagtttt aaaaaagcat tccaaacatt
     6541 caaaaatagt tggaacttcc cttaataaat ccgtcacttt ctttttcaag atagcccaag
     6601 cttgctcaat aggattcaaa tccggtgaat aaggtggtag aggtaagaaa aagtgtttat
     6661 cttggatgca gagttcatcc aaaatgttct tgggatgaaa actagcattg cccatgacaa
     6721 taacatgagg tgtcttcaaa gcaggtagga gttgcgtttt gaaccactcc acaaagaaat
     6781 cgcttgtcat gcttttcttg taaatcatgg gagctataaa ctctccgtct acttgtcctg
     6841 caacaattga agttcgctca aaacgacgtc cgctaatctt ttcatagact ttctcccctc
     6901 taggagcccc tgcataagga cgatagaggt agcggtcgat tcctgtttca tcaatatata
     6961 cgattggtaa atcttttagg ttatccaaaa tatcaagaaa ctcagcgact ttctctgact
     7021 cttgttcctt aaagatcgtc atcttttttt aaagtgacct taatctgctt taaagctgcc
     7081 catactgaag gaacagcaca atcaaaatgt gccgcaattt cccgtaaaaa agcatctgga
     7141 tgagcctcta caaaggcttt caattcttct aaagggatct tacgcttttt gacgactcgc
     7201 tttttccgct ctaagttcct ttgttcacgt ctttcttttc ccacgtgaag agagttctga
     7261 cgccaacacc aaaaaacttt ggccgcctcg acatgtctgt gccctccttt gatggaatct
     7321 aatgctcctt gtttaaaatc agtattatat gccatagctt tattagacca tgcttatttt
     7381 aaactaagca actatatcaa tgttttgtta tgagaagact tacttttttt actgaaattg
     7441 aatttttcct agcctcaaca tcatataacc ccaaaattca atctgacctg gtttgaagag
     7501 atgttcgaag cagataaggt tttactaaaa ctaaaaaaaa tgatataatc aaactgatta
     7561 aatgttttaa aaataaagga gaatttgaat gtcttaccaa gaaaattacc agaaatgggt
     7621 tgattttgtg gagcttcctg actaccttcg tcaagatttg gaaaatatgg acgaaaaaac
     7681 taaggaagat gccttctata caaatcttga atttggtact gcaggtatgc gtggcttggt
     7741 tggtgctggt acaaaccgta tcaacatcta cgttgttcgc caagctactg aaggattggc
     7801 tcgtttgatt gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga
     7861 tagccgtcac ttctcacctg agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg
     7921 catcaaatct tacgtatttg aaagccttcg tccgactcca gaactatcat ttgcagttcg
     7981 tcatctcaac tgtttcgcag gtatcatggt cacagccagc cacaaccctg ctccatttaa
     8041 cggttacaag gtttacggtg aagacggtgg acaaatgcct ccacacgatg cggacgcttt
     8101 gactacttat atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac
     8161 tgaaaaagct tctggcttga ttgaagttat cggcgaagct gttgacgtag aataccttaa
     8221 agaggttaag gacgtaaaca tcaacccagc cttgattgaa gaatttggta aagacatgaa
     8281 gattgtctac acaccacttc atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca
     8341 agcaggattt gactctgttc aagttgttga agcgcaagca actgctgacc cagacttctc
     8401 aactgtaaca tctccaaacc cagaaagcca agcagccttt gcccttgctg aagaacttgg
     8461 tcgtcaagtt ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt
     8521 tgaagttctt caaaaagatg gtagctacct caacctttca ggtaaccaaa tcggtgctat
     8581 catggctaaa tacatcttgg aagctcacaa aaacgctgga actcttcctg aaaatgccgc
     8641 tctctgcaaa tctatcgttt caactgactt ggtaacgaag attgctgaaa gctacggcgc
     8701 aactatgttc aacgtcttga caggtttcaa atttatcgct gaaaaaatcc aagaattcga
     8761 agaaaaacac aaccacactt acatgatggg atttgaagaa agcttcggtt acttgattaa
     8821 accatttgta cgtgataaag atgccatcca agccattctt gtcgttgctg aacttgctgc
     8881 ctactaccgt tctcgtggtt tgacacttgc tgacggtatc gaagaaatct ataaagaata
     8941 tggctactac gcagaaaaaa caatctctgt tactctttca ggtgtcgatg gtgctgaaca
     9001 aatcaaagcg attatggcta aattccgcaa caatgctcca aaagaatgga acgcaacagc
     9061 tatcactgtc gtagaagact tcaaggcaca aactgctact gttgctgacg gtactgttac
     9121 aaacttgaca actcctccaa gtgatgtgtt gaaatacaca cttgctgacg gttcatggat
     9181 tgccgttcgc ccttcaggta cagaaccaaa aatcaagttc tacattgcag ttgtagggga
     9241 aaccaacgaa gaatcacaag ctaagattgc taacatcgaa gcagaaatca atgcatttgt
     9301 aaaataaaga cctataaaag atgagaccaa ccaacctcat cttttttcgt atcaaatcta
     9361 agcaatttta gaaactttat ggcatactag acttatcaat gaaagcgagg taatctcatg
     9421 gaacaatttt tagataacat caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa
     9481 gctcttgata aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg cccttactgc
     9541 cgtaaatttg caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca catttacttc
     9601 atcaatagtg aagaaccaag ccaactcaat gatttgcaag cattccgctc acgctatgga
     9661 atcccaactg taccaggttt tgttcatatt acagatggac aaatcaacgt ccgttgcgac
     9721 tcttcaatgt cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa
     9781 gtcttaaaat cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta
     9841 ttgttcctaa aacagttaca tcagcatttc attacagaac attttaattt tggaagtcaa
     9901 atcaattttt aacaatgttt tagaaatcac agtgggctat tccatattaa attatccaga
     9961 ttcaatcgct attatcgttt tcctagatta caaaaaaact gcgttttgct aatcaaaacg
    10021 cagtctcagc cactatttta tcttactgtc cttcttttac ttctttggtt gctacatctt
    10081 ctccaaacca tttttggctg atttcttgga acttgccgtc cttgtaaaga ctagaaaaag
    10141 cttcatttat cttcttaacc aaggttgtat cttccttacg ggctccaacc gcaaaagctt
    10201 ctgtttctag tccaactgta aagacattat aatcgtttaa aacaccttct gcttctaaat
    10261 aatagtttgc atagacacgg tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa
    10321 tcaaggcttc attaaaggtt tggtattgat tcgcttcctt attagcgaca atattcttca
    10381 aaatttctgg atttgcttca aagtccgcat aaccagatga accagcttga gctcctaatg
    10441 tctttccagt catatccttt gcagtcgtga taccagatga tttcttcgta accaatacct
    10501 gctcattctt catatatgag ttactgaaag ccaccttttc acggcgttcg tctgtagcgg
    10561 aatagccatt ccaaatcaga tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc
    10621 aatcaatcgg ttgccaattt accgtgattc cgtatttttc aaaaacagct gtagctaaat
    10681 caatatcaaa tcctgcataa gaaccatctt tctgagcaaa tcccattgga acaaaagtac
    10741 tatcaaatcc aatagtaata gacttgttag actggtactt tgaccaatta tctccactag
    10801 tttcgctaga atttttccca caagctacta agaacaaagc agtcatcaga ctgactaata
    10861 caagcatcca ttttttcatc catttttcct cctatttagg ttctactttc aataatacat
    10921 ctgcgatatt ttcagcaaac tgcaaatcat gggtaaccac aatctgggtc atcccaagtt
    10981 ccctattttg caagattagc ttctccactt ccaaacgtaa ttctggatcc agggcagaag
    11041 ttggttcatc gtagccaatg atttctgggt caatcatcat agcacgcgcc aaagccaccc
    11101 gctgcttttg cccaccagat agtgagaaag gataggcctc tgcgtgtcct cctagtccta
    11161 actgttccaa gagtccactc gccttcttct cagcctcttc ctgcttcatt cccatggtct
    11221 tcacaggcga taaggtcaaa ttgtccagaa ctgataaatg agggaacagt tgaaaatctt
    11281 ggaatacaaa tcccagtaga ttgcgcttct gcaattcatc cagctctaaa ggttgtccat
    11341 tataaaagat ttgccctgaa tcaatggttt caagacctgc aagcatacgt aaaagagttg
    11401 tcttacctcc accagaaggt ccaacgatag ccaggatttg cttttcagga atacttagac
    11461 tgaaattaga caggatttgt ttgtctccaa agactttatt gatatttcgt aattctaaca
    11521 tggcagcctc ctatctataa taactatact tcttctcaac ttttttggaa ataattgtca
    11581 caatcccaat caaaatcaaa taaatggctc ctgccaagaa cataggaact agactagcat
    11641 cgcggttagc agctgttcga ctagccaaga taaggtctga aattccgaga gcatagacca
    11701 aagaagtatc cttgaccaaa ctcataactt cattaaagac actaggaaga acgatcttgg
    11761 tcacttgggg caagataata tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg
    11821 cggcctcata ctgtcctctt ggaatagtgt caattccccc acggaaaatt tctgcaaagt
    11881 aagctgcata gttgagaaca aaggcaataa tagctgcagg aaggcggtct aaacgaatcc
    11941 caatacttgg gagcacataa tagataaaaa tcagttgcaa gagtaagggg gttcctcgca
    12001 taacccagat gtaaatgtta atcagataat ggaggggctt ccaatggact tgcaaggcaa
    12061 aggcaatcaa aacgcccaag ggaatcgaaa atagcaagac cagtgcaaag acctgtacag
    12121 tcgtgctcgc accattcagt aaactcggta atatctcaaa taaataagac atactgcacc
    12181 tcctaaaagt aattgttcct attatagcat gaataaacaa gattaccaag tatttttgta
    12241 aaaagattct accatataca aataaaaacc gtagctatca aaagagataa actacagttc
    12301 tatatgttta aacattctta caatctctca aacagttctt gcatttgcac atcatctgga
    12361 accagtttta agtaagtgtg agcatggact tttgcttctt caaaatgtcc caattcacgc
    12421 aagagataga tatagtgttc cagaaattct ggattgtcct tcaaatctcc tatcaactct
    12481 tgataatgct cataagcagt atccaaatcg tccatttctt gataagaacg agcaatcatc
    12541 cacttggtca aaagattttc tgactcctca ctctgcaagt ctagaatatc ctcataacgc
    12601 tcctgctcca gataaatagt ggctaaacga agcaagattt cttctgtatc ctcagcgtct
    12661 tcttttgcag taaggagata attttctgca ccactagcat catgcaattc ataagaaaat
    12721 tgtgaagcag ctagcaagag gcgagtttca aagggatttt tctctaatcc ttgcttagcg
    12781 atacgcaggg cttcttgaac ttgatgttcc ttatgtaaag cctgactgta cccatactca
    12841 tagccttcaa agtcaggaga aatggtatca agctgcttaa agtagagggt ggctttttga
    12901 tattcttctt gatcaaaata aagactggcc aactcaaaag ctgttaagtc atcgtattct
    12961 aactccaggg ctttttctaa aaactcagta gccgtttcaa atttccctaa ctgagcatag
    13021 gcaaagccaa ttcgttgata ggtggaaatg cccgtttgct cataaatcga gcgattatct
    13081 aactgggcat aggcttgaat agccgcttgg taattttcca actcactatc caactctgcc
    13141 aaacccaata tcaagagaga atcctctgag taggtcaagg cctccaataa tttctcacgt
    13201 gccacatctg tcaaaccttc cagctggtaa aggtctgcct tcagagccaa agacgagaca
    13261 taccagtcac tgtcagcttg gatttcctca agataggtaa aggcttcttc tatttgacca
    13321 tcctcgctag caattgcagc tagattaaga tgaacctctg gaaaatcctc tacaattttc
    13381 aggtaaattt ccttggcctg aggatagaaa ccaatccctt caagataagt tgccaactca
    13441 tacagaagat cacttgaatc attttctaaa gctttggcga aataatgctc agccttagtt
    13501 aaatcttgct cctccaaagc ctgtaacatc tgttgactat tgttcactct tgacttcctc
    13561 accctctaat tcatatagac cactgactac cttataccat tcgaaaatgg ctgaaatgac
    13621 aaccttagca gaggcataaa ccggaatacc aagtaaaact ccccagatac caaacataga
    13681 tcctgaagtt aacaaaacaa agagaacatt aatagggtgg atgtttaatt gacttcccaa
    13741 aatcaatgga gagacaaaac ggccttcaat agtttgttct acgataaaga caatcactac
    13801 tttcaaaagc atgactggac cagcaatcaa acccaatact agagcaggaa gcatggctag
    13861 aaagctacca agataaggga ccagatttaa aataccagca gtaaccccca gcgtaaccgc
    13921 atagcgtaga ccaataatct tgaagaagat gataaacatt actgctacaa taatagccac
    13981 tgtcacttgc cctcgaacat agttggacaa ctgttgattc acatctgata aaacttgtcc
    14041 aacaggttcc ttcaattttc ttggaatgaa ttgggtcaaa tagttacgca agcctttccc
    14101 atcacgcaag agataaaaga gcatgaaagg aacgataatc aaggcaacaa tcacttgaga
    14161 agctccgcta ataaaggcac tcacccagtt gactgcctga gatgaaacct tacttgccaa
    14221 aactgtagcc tggctagaaa aattggtcaa aacttgctct aattgaggtc tgaaatcatc
    14281 tggcaggtgc tgggctacca atccattaac aatcctatct atatcttcta agtaaacagg
    14341 aacgtttctt gcaaaggtca aaacctgacg ttgcagattt ggaatggcga ctgccaagcc
    14401 ccaaatgata aagagagcga tgataacaaa gacaatagtg atagctataa cacgattaac
    14461 cttatgcttc tccatccaat caacaatagg attcaacaaa taatataaca aaccagacaa
    14521 aatgactggc aacatcacaa ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat
    14581 cttacttaaa ataaaaagat tcagtcccaa taataaggtt actaaaaata ccgtaattgc
    14641 cttgttatct aaaaaccact tgaaaaacca agataggcta aaatgtttct ctttttgctc
    14701 cataaatact tcctttctat tgttctctca ttataccatt tttgaaacaa aataactctt
    14761 ttttaaagtg cttacatcta attggatatc tttaatttac ttgtttttgt gatataatag
    14821 tcttatcttt acacagaggt atagtaatga aagaaactgt ttattttgga acttatacac
    14881 gtcgtacttc tcaagggatt tacaaggcag actttgatac agaaactggt cagctttcaa
    14941 atctagaact ttttgcagct gagccaagtc caacctacct tgcctttgac cagcaccaac
    15001 atttatacac tgttggtagc caagacgata aggggggaat tgcagcctat caaactgacg
    15061 ggactgtgtt aaatcatgtt gttgaagaag gagctcccca ctgttatgtt gctgtcgatg
    15121 aaaagcgtga tttggtttac gcagccaact atcacaaggg acaagtcctt gtttataaac
    15181 gccaggaaga tggtagtctt ctacttagtg atatggatca acacagtggc caaggtccac
    15241 atgaaaatca agcttccccc catgttcact atacagattt aacacctgac cactatctag
    15301 tgacctgcga cttgggaact gaccaagtca tcacctatga cctcgatcaa gaaggaaaat
    15361 tatctaagct ctatacctat cacagcaagc caggagcagg ctcacgccat atcattttcc
    15421 ataaccacta taaaatcgct tatctcattt gtgaactcaa tagtactatc gaagttttaa
    15481 tctacgatgg cgttggcgaa tttgaacgta tgcaggtcat ttcaacttta ccggaagctt
    15541 acgaaggctt taatggaacc gctgctattc atctctctaa agacggtaaa tacctctacg
    15601 cttctaaccg tggccatgat tctatcgcag tatataccat ccttgcggac ggtagcttag
    15661 agttattaga aatcgttcca acgcatggtc agactccacg tgattttgat ttgacacccg
    15721 accaaaaatt tctcattgtt gtccatcaag actctgacaa tgcaactgtc tttaaacgta
    15781 attgtgacaa tggtcgtcta gcagaactct ccaacgactt ccatgttccc gaagcagtct
    15841 gcatccgttt tgctccttaa aacaccataa aaaatgaact tggtattttc aagttcattt
    15901 tttcttatag tctatttccg acattaatac ggttaatagc acgttgcaaa gcaatcttag
    15961 cacgacgttc ttggtcaatc aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac
    16021 gaagtttggc acgttctgca cgactgatat cgatatcacg agcacgttct gcagagtcag
    16081 cgacgattgt gatcatatca ttggcaattt caataacacc accgtttact gcaatccagt
    16141 tcacgtgatc tttatcatcg atacgtttta cctttacttc atcaactgct aaaaccgcaa
    16201 tcatattttc atgtcgtggc aagatcccca tctcaccatc cagagttcga accgatacat
    16261 agctggcatg gtgatcatag acgagaccat ctggtgtcac gatctggaca gttaactgag
    16321 ccatagttca cctcttaaaa tcccattttt tcagcttttg caatcacatc ttcgatagaa
    16381 cctacaccac ggaaggcatc ttctggcaag tggtcgtatt taccatcaag gatttcctta
    16441 aagccacgta cagtttcagc aactggaaca taagaacctg gctgaccagt aaattgttcc
    16501 gcaacattga agttttgtga caagaagaac tggatacgac gggcgcgagc aaccaaggtc
    16561 ttttcttcat cagaaagttc atccatacca aggatagcaa tgatatcttg caattcatgg
    16621 taacgttgaa ggacacgttt tacttcagca gcaactgcat agtgctcttc tccaacgatt
    16681 tcaggtgcca aggcacgtga gcttgaagca agtgggtcaa cggctgggta gatacccaat
    16741 tgtaccaact tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc
    16801 gctgggtcag tatagtcatc cgctggcaca tagatagcct ggatagaggt tacagaaccc
    16861 ttcttggttg atgtgatacg ttcttgcaat tgacccattt ccgtagcaag tgttggttgg
    16921 taaccaacgg ctgatggcat acgacccaaa agggcagata cttctgaacc agcctgagtg
    16981 aaacggaaga tattatcgat aaagagaagc acgtcttggc cttccacatc acggaagtat
    17041 tcagcgattg tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc
    17101 tgaccaaaga ccatggctgt tttctcgata acgcctgatt ctttcatttc ccagtaaagg
    17161 tcattcccct cacgagtacg ttccccaaca ccagcaaata ctgaaatacc accgtgctct
    17221 tgggcaatgt tgtgaatcaa ttcttggatt aagacagttt taccaactcc ggcaccaccg
    17281 aaaagtccaa ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac cttgatccct
    17341 gtttcaagga tttcagaaga ggtagacaac tcatcaaaag ttggagcttt tttatgaatt
    17401 ggctgacgct ctgcgtcttc tgtaaaagga gcttccaagt caatggtatc tcccaaaacg
    17461 ttgaagacac gtcccaaagt ttctttacct actggtacag agattggacg acctgtgtcc
    17521 aatacttcca ttccacgagt caacccatct gttgattcca tggcgatagt acgaaccata
    17581 ccatctccta actccaaggc tacttcaagg acgatttttg tttttctttc gtcatttttg
    17641 tagacgacaa gtgcattgtt aatctcagga agtttttccc ctgctgcaaa caaaacgtct
    17701 acaacgggac cgataacctg agcaatttta cctgaactca tctccttctc ctattctata
    17761 taagatactg tcggttccta gctcaactag gtcctaagtt cattttcata cgagctggac
    17821 tagagcctat tctaaggcac tagcacctgc tacgatttct gtaatttctt gtgtaatcgc
    17881 cgcctgtctg gcacggttat actgaattgt caaatcattg atgactttct tagcattatc
    17941 tgtcgctgtt tgcatggctg tcatacccgc agcattctca gctgtcttgg catctataat
    18001 ggcaccgtaa atcatacttt ctgcaaactg aggcaacaac tgctccagaa tttcttctcg
    18061 gctggtttcc aattcaaaag tcaagctgta ctcttcatcc gcttcatttg gatccaagtc
    18121 aacaatcgga agcatttgtt ccacacgcat ttgactggtt agcgtattga catggtggtt
    18181 gtagcaaaca taaagctcat caaagagttc attttggtac atttcaacag tttttgaaat
    18241 aatcttacga acttgatcaa agctaggttg gtctgccaag ccacgtaatt cataaagtgg
    18301 ttgaataccg cgagccttaa agaaatcagc tcccatccca ccgatacaga tcatttcaaa
    18361 acctttaccg tctgggtggt attcttcttt caactccata acagctttca aaatagagga
    18421 attataacct ccaaccaaac cgcggtctga agtgataacg atatagcctg tcttcttcac
    18481 agaacggcta atcaacatcg gattagttga agcaccagct ccattaccat gaaggatatc
    18541 tgtcaaaagt ttacgcactt tctgagcgta aacttggaag ttgcgagcag cttcttcaga
    18601 gcgacctagc ttagcagccg ataccatttg catggcatta gtgatttgac tcgtattttt
    18661 tgttgaggcg atttttgttt taatatcatt tagagatact gccatctgac acctctattc
    18721 ttattggaag ctagattgat tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc
    18781 tggcaagtct tttgtatcac gaatggtttc caaaatctct ggatgttgag catcaaagaa
    18841 ggcatggaac tcttcctcga aacgaacaat atcatctact ggaacagtat ccaagaaacc
    18901 atgtgtcaaa gcataaagaa tggttacttg tttctcaaca ggtaatggtt tgtgaacagg
    18961 ttgtttcaag acctcaacgg tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc
    19021 caagtcagaa ccaaacttag taaaggcttc caactcacgg tatgaagcaa ggtcgatacg
    19081 aagtgtacca gcaaccttct tcatggcttt gatttgtgca gaaccaccta cacgagatac
    19141 agatgaaccc gcatcgatgg ctggacgaat acctgcattg aagaggccat cgccaaggaa
    19201 gatttgtcca tcagtgatag aaatcacgtt ggttgcgata taggctgaga tatctcctgc
    19261 ttgtgtctcg ataaatggta gggctgtaat tgatccacca ccaagttcat cagaaacttt
    19321 agctgagcgc tcaagcaaac ggctgtggag atagaaaaca tcccctggga aggcttcacg
    19381 acctggagga cgacgaagca agagcgacag ttcacgataa gctaccgctt gttttgatag
    19441 atcatcgtat acaatcaaaa catgcttacc ttgatacata aattcttccg ccatagcgac
    19501 cccagtataa ggagctagga agagcaatgg agatggttgt gaagcagagg ctgtcacaac
    19561 gattgtgtag tccaaggcac cgtactgacg aagtgtttct acttgcgtac gaactgttga
    19621 ttctttttgt ccaatcgcga cgtagataca gatcatatct tgatcttttt ggttcaagat
    19681 tgtatcaatc gcaatggttg ttttccctgt ctgacggtca ccgataatca actcacgttg
    19741 accacgacca atcggtacaa gggcgtcaat agctttcaaa ccagtttgca atggttctga
    19801 aacagactta cgttgcataa caccaggagc tggtgcttct actggacgag ttttatcagt
    19861 gtggatttct ccaagaccgt caactggacg accaagcgga tccacaacac gaccaatcag
    19921 actttcacct acagggactt ccatgatttt ccctgtacgg cggattgtat cgccttcacg
    19981 gatatctgta aagtcaccta ggatgataat accaacgtct gttgactcca agttttgagc
    20041 cataccataa gagccgtttt caaaattcaa caactctcca ctcatgacat tttcaaggcc
    20101 gtgagcacgc gcgataccgt ccccgatata ggttacaaca cctgtttcag tcacatcaaa
    20161 attgggtttg aaattttcaa tttgttgctt aattaaagcg ctgatttctt gtgcgttaat
    20221 tgccaaaaga acaccacttt ctatttcaaa ttttctttaa caactttaag ttgttgttta
    20281 atactcacat caattgtctt gtgattggca aaaatgacaa aaccaccaat gagactttca
    20341 tcgatttgtt cttttacact ccttactttc agagacattt ttttctcaat caaagggagc
    20401 aaacgagtct tctgttcatc agttagagga tgagcagacg taatcgtcac ttcaaatcga
    20461 tttgtttctt tttcaagtcg gttcaagcaa tctacaagca catcataaaa aagatttgct
    20521 ctgtgattgt aggccagaac ctggataaag ttttgtaata aaggcgacac agaatcttgg
    20581 aaaaaagcaa ttgttttttc cttatccgac tcgtctactg ccacttgttt taaaaaagaa
    20641 ggcagacctg ttttttcaac aacttgcttg atttgagtca agtctgaaaa gatacggtct
    20701 tcttctcctt tttcaagtac caattggaca aaaggcatgc tgtatttttc aattaccttt
    20761 actgttttct tgtccattaa gcttctccta gctgatcgat atactgatca atgagtgctt
    20821 tatgggcatg actgtcaagg ttttgtgaga tgattttacc agctaagctg atggtcagat
    20881 ctgcgacctc acccttaaca ctctgtaaag cttctacttt attttgagca atttcttgat
    20941 tggctttttc ttttaagtgt cctgcttcta gtttagcatc tgctaagata ttagccttac
    21001 tttgctcagc tgtttccttt gcattttcaa tgattgtctt agcttcttta cggctaccag
    21061 ccaattcatc ttcgcgtttt tgagccaata cttctgcttt ttgacgggct tcttcagctc
    21121 tgtcaatatc tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta atattagacc
    21181 atgcaaattt tttaatcaag actagcaaaa gaataaaaga gccagtgatt aaaataaaat
    21241 taccaattaa ttcacctact gttacgtgca tcagttactc ctttctattc ctcttcaata
    21301 ttaatcttat tccctaaata cacagatgtc aaaagagtaa aaacataagc ttggatgcag
    21361 gaaataaaga cagaaaatgc agtccaagcc aaattagctc caaaggctac tggataccaa
    21421 taaatagctt ggtgggaaag aagaagtaac aaactcgtca tgacctctcc tgcaaagata
    21481 ttcccaaaaa tccgcaaagc caaagataag aagtttgtaa attcttccaa gatattcatc
    21541 ggtatgacaa aaacaggact cataaaagat tttatacttt ttttaaatcc acgacgacga
    21601 acgctttcta tatgtgtcaa caaaatgaca agaaaagata aggttaagtc atactgtaaa
    21661 ttagcggttg gcgaactcca ccagttagtc ccatcgatcg tttgaagctt tgtcattaag
    21721 ccaaggttat tggcaatcac catgaaaagg aataaacaaa ggaaaaagag tgaataatct
    21781 ttcatgtagc gcgaaccaat attaggttct gtaaatccaa taacaaagtc atagacatac
    21841 tcaagtacat tttgctttcc tttgggtttc aaggtcatat tgcggcttgc ccaataaata
    21901 aagacaaaaa taactcccac aatcaacaaa gtcatggcta acatagtcag attgaagata
    21961 acaggaccaa tagagatgat tggattaata ctttcttcca tctaaaatcc tcccttttct
    22021 tctcgttcca tgtatttatt tgataataaa tgagaagaca agagttacaa agaaagttcc
    22081 ttcaataaag gcaacaccta aaaacatcaa actacgaaac tcagaaagca tatctggttg
    22141 gcgtgctact gatttaaaca gtccattcat caataaacct tcaccgacag atacgcccat
    22201 acaggcaata cataagccta aaaatgttaa attcataaca aattctcctt taaaataaaa
    22261 tttacttact tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg ctattggaag
    22321 cgtttaataa aaattatttc cattttgcta aatttcaagt tcaagttagc catccaaaag
    22381 tcttctctgg gtgacttgta gtccaagcat tttttaggat agttgttaat ccacttttcg
    22441 atgaatgcga cttctttggg agtcattttc ttggttccct taggtaacca tctacgaatg
    22501 agcctgttgt gattctcatt agttcccctt tcccaagagg catagggatg tgcataataa
    22561 atgtgctcct cagaaaatac attagacaag cgattgaatt ccgttccatt atctgccgtg
    22621 atggaaagaa tcttgtgttg ttttaagatg agttttagag cctgattgac cacctcagca
    22681 cttttatttg gaatcaatcg gatgatctga tgtctacttt ttcgatccgt caagacaagc
    22741 aagcagtagt ttttcgctct cgtaagtaga actgtatcaa tctcataatg cccattctcc
    22801 aagcgaaaat tgatagcttc aagccgctgt tcgatggatt gaccagcagg tttaaagttg
    22861 gtgctagcct gtttcttaag cgcttttcct tttctagggt aaggcaaatc ctgcttgctt
    22921 aaccccaatt ttccatgatg aatccaatag taaatggttg aaattcccac gttaacccct
    22981 ttagccataa ccatcatttc aggcgaaaat ttttggttat gatagtggag aatcttttcc
    23041 tttagttcct tggtcaagct tgatttcttg accgagcgct tgcgattgtt ttcataagac
    23101 tgttgagcat agtcggcaga ataaacctct ttgaagcgcc cttttccaag acattgtcgg
    23161 actgtcctac gcttgatttc agtgtggata gtttgaggag cttttccaag tagagaggca
    23221 atttctctat ttgatttccc tttgttcgcc ttttgtagta taatggtttt gcatctctgt
    23281 gcctttcttg tgtttgtggt tgaacaacaa gtataacaca aaggtgtttt cttatgccta
    23341 caagagcttt cattatttcc attttctttt ggatttcact ctattctgaa aaacttgtgt
    23401 atatttactg aagctagcaa gtcttacctg taaatttaat gaaagcaaca caaaatccga
    23461 gaggggaatc tcggattaat gtcaatttaa aaagatagag agtttttagt ttaaataaat
    23521 tgttttaaaa tatcaacaac atcacttctt ttcttaacct gataagcctt gattcctaat
    23581 tttggggcta cgattatatt gtcctcaata tcgtctagaa agacacaatt tctaggttat
    23641 aactggtatt tatcgatagt tactcatata tatcagtcca cctccatact caccttacag
    23701 attcttttga taataatatc tttgcctaat gtagagatag tcttgcaaag aaaaaacttc
    23761 cttgtagcca tgtttctgat aaaagtccgg tgcctggaac tggtaagtat tgacaaaggc
    23821 aaaacaacaa tttcgattct tagcttcact ttctgcctgt tgcaatagtt ttgaaccgat
    23881 tccttgccct cgcagttcct cttttacaaa caaatactcg atttctagcc aatttccaaa
    23941 agtctctgct atcaaacccg caaggagatt gcccttttca tcttcgacat aaagattaag
    24001 tggctcactt tcagcctctt ctctttttga acggttataa acacgaatca gattccctat
    24061 ttcttgcgat ttatgtgatt ccttattttc caatctaaag tataatgaaa tgaaataaaa
    24121 catgcgcaaa tcgattaagg aatttaatct aatttctaac aatgtcttag aaatcaaagt
    24181 gtactatttt aacttcaatg cactatacat ctaatactca ataaaaatca aagagcaaac
    24241 taggaaacta ggcgcaggct gctcaaaaca ccgttttgag gttgtagatg aaactgacga
    24301 agtcagctca aaacatggtt ttgaggttgt agatgaaact gacaaagtca gtaaccatat
    24361 atacggcaag gcgacgctga cgtggtttga agagattttc gaagaatagc aaaatggaaa
    24421 aaggagtgag tgaagcacat cgcctcccca ctcctttttc tgtttttagg ctgttttttc
    24481 aaccttcaag atttttacat catagctacc aacaggcgtt tcaatggttg ctgtgtcacc
    24541 tgttttcttg ccaatcaagg cctgcccaat tgggctttca tttgaaacct tacctgcaaa
    24601 ggcatccgca ccagctgaac ctacgataat ataaacttct tcttcgtcct caccaatttc
    24661 ttggatggtg actgttttac caatcgctac ttcgtcctgg gcaactgcgt cgctattgac
    24721 gatttcagca tagcggattt ttgtttctaa gctagagatt tgtccttcga caaaggcttg
    24781 ttcatcctta gctgcttcgt actcactgtt ttctgaaaga tcaccgtatg aacgggcaat
    24841 cttaatgcgt tctaccactt ctggtcgacg aaccaatttc aattcttcta attctttttc
    24901 aagtttctcc ttttcctcaa gggtcatagg atatgttttt tctgccattt ttctcaactt
    24961 tcttctgata atattttcta aagaaaatta tgtgaagtat cacataattt tagtttgttt
    25021 agtttaattt gctgttgaca tgttcagcga cattgcggtc gtggtcttct tgattgttag
    25081 catagtagac cttgccttct gtgacatctg ctacaaagta gaggttatcg ctcttagttt
    25141 gattgatgct tgactcaatc gcatccagac ttggactatc gactggacca ggcatgagac
    25201 ctacattttt ataaacatta taaggtgaat caatgtcggt atcaatcgca acatcctcag
    25261 ctagactgat attttgcccc agttttcctt gggcatacaa gattgcaata ttactttgaa
    25321 gtggcatatc acgatttaaa cgattgtaga atacacctgc aatgagctta cgatcttctg
    25381 tcttggcacc ttctttttcg accaaggaag caatggtcaa caactcattg atagtcaagt
    25441 ttttagattt gatagtacta tagtaaggag ataggttctt atccatagca gctaacatct
    25501 catcaatcaa gctctcaata gttgtgcttt ccttgataga gtatgtagct gggaaaaggt
    25561 atccttccaa acgataacgc gcaccgctgt cttttacagg caaactttcc agtaaagtag
    25621 gatatttcgc tactgcttga ctgataaacg tctcatcttg aactttagcc aagaaagcct
    25681 ccgctgtcaa agactctttg aagtcacctt gcaattgacc cacagtttga gcaatctgat
    25741 ccaaggtata accttctgga attgtcaaag tcgcaagtac aggttcttgc ggttcatctg
    25801 ttccaccttt ttgcaactct ttgagtaagt cttctgtact catactcttt tgcaaattgt
    25861 agtaacctgc tttcaagtcg gtataatttt tatacttggc ataaaaacta aaaatcagac
    25921 catgctttac caaaccagct ttttcaagcg tcgtaccgat ttcttgaacg tttgaacctt
    25981 ctggaattcc aaccgtcaca tatttcttag aattagcatc gataggtaac aaagaatcta
    26041 gcacgtactg gtaaccaaag taaccacctg ctgagagcaa ggcaaggaat acaaggaatg
    26101 aaatcacaaa agctttcaca tgtgacttct tctctttctt aggtttaacg ggttttgctc
    26161 cttctctacg gctacgacgt gatgtatcgc tgatgatatc cactgtttct gtagcaggcg
    26221 taggtgtttc tggacctgct tgttctgctt ttttctctgc cgtcgtatag gaaacagcta
    26281 cccttgttgg ggtttcattg tattctcttt caagtttctt aggtctaaca ggacctggac
    26341 ctggtcttga tccactttct tccgctggag aagaaggtac atcttgactt ggatgacttg
    26401 gaacaccagg agtttctctt tgaatctcat ctgctggaga agctggtaca ccttgacttg
    26461 ggtgagtagg cacggtagga gcttttctca taatctcctc taccgttgac aaggaatcag
    26521 ccatgagttc ttcagctgaa ggttcatttg caggagtgcg aactactgcc tcatcttctt
    26581 tcagaacttc atcatagcct tttacttttt ctaaatctct cagaatctgc tctttaaagc
    26641 ttaatttctc ttcttctctt gacttttcac tcaaaagttt ttcctccttg ttgataatcc
    26701 ataatattat atcttaaaag tccaaaaaaa gcaatctatg atacttttcc taacttattt
    26761 tttcatttcc cagaccatat cataccatgt ttcccctgca aaggttgact gggactggcc
    26821 ttcgttgaca aatccatgtt tttcatagta ggcgatgaga tagtcatgac aggttagatt
    26881 aatgccatct ctctcatctt caagagcaac ttctttcaag gctgtcagca atttctgacc
    26941 cagtccgagt ccctgtgcct ccttggcaat agacagacag gtcacagaga tataaccacc
    27001 aggctcatga ctatagtctt ttatttcttc tgtaaaagac tggtcttgca gatggcggtg
    27061 caggccaact ggtccttcga tataacccat gattcttcct tctttttcag caaccagaaa
    27121 agaggtctga atttctctca aatgtgcttc aaagacagaa ggaggaatgg cttcttcgac
    27181 cgaaaaattt tcaaattcaa gttcaacaat ccgatccaaa tcttctaatc ttgcttgtct
    27241 gattttcatt gttcctccag ataaaaggga ttaaaccaaa tcatactata gccctggcta
    27301 gttgcataga gcaaagtttc ttcttcatca acaaaaccgt tcatttcaaa ataggaaagc
    27361 agctcatcag gactctccaa acgaatccct ttgcaatcca gctcaactgc cacctctttc
    27421 aaggctgcaa gaagaagtgt tcccaggccc tgtctctgat ggtcagactc gatgactaaa
    27481 gaatgtactt ttagacattg cggattgtct gactggggac ttgataaaat atagcctaaa
    27541 agttgatttt catccctagc tagaagaaag gtatccgcac acttacggat actttcttct
    27601 aaaatatggg aaagttgctg cttttcagct ggaaaagacg aggtctgaag tgcccctatc
    27661 tcaggcaaat cagacttgct tgcctgaatg atcttaattg gaatttccat gggaacatcc
    27721 tattgaacat tgcttgtcaa gttagataag agacgctcaa atgagtattc ataggtttgg
    27781 atgtctcctg ctcccataaa gacgtaaaca gcattgtcat ggtctaggag tggagaaaca
    27841 ttttcaacag taatcacttg gtgttttttg ttgattttat ttgctaggtc ttctacctta
    27901 acgtcaccat gatctacttc acgagccgag ccataaattt gcgctagata aacagcatct
    27961 gcttggttta aagcatgggc aaagtcgtcc aacagggcaa tggttcttgt aaaggtatgc
    28021 ggttgaaaga ctgctacaat ttccttgctt gggtatttct gacgagccgc atccaaggtc
    28081 gcaataattt ctgttggatg atgggcaaag tcatcaataa tcactgtatc attgacaatt
    28141 ttctcagtga aacgacgttt aacaccggca aatgttttca agtgctcacg caccaagttc
    28201 aaatcaaatc ctgctgtgta aagaagacca ataacggctg tcgcattcat gatattgtga
    28261 cgaccaaagg ttggaatgtg gaattgcccc aagttttgtc cacggaaatg aacggtgaag
    28321 gttgaaccag ttgttgaacg aagaagatca ctagctacaa agtcattgcc ttcagcttca
    28381 aaaccataat aataaattgg tgcatcagac gtaatcttac gcaattcagc atcttcacca
    28441 tagacaaaaa gacccttggt aatttgtttg gcatagtcgt taaaggcatt gaaaacatcc
    28501 tcgagacttg tgaaataatc tggatggtca aagtcaatgt tggtgataat agagtattct
    28561 gggtggtaag gcatgaagtg acgctcatat tcgtcagatt caaagacaaa atatttggca
    28621 ttagccgaac cacgacctgt cccatctcca atcaagaagc tggtatctgt aatgtgagac
    28681 aagacatgag acaacatacc tgtcgttgaa gtttttccat gtgctcctgc tactcccatg
    28741 ctaacaaagt cacgcataaa gctacctaga aactcatggt aacgtttgta gctgatacca
    28801 ttttggtccg cataggcaat ttcgacgttg ttatctggac gaaaggcatt tccagcgata
    28861 atttccatat caccgtctag attcttttca tcaaaaggaa gaatggtaat tcctgcctgc
    28921 tcaagaccgc gttgggtaaa gtagtacttt tcaacatctg atccctgaac cttgtgcccc
    28981 atctggtgca acatcaaggc caaggcactc atccctgatc ccttaattcc gataaaatga
    29041 tatgtctttg acatgttttc tcccctattc tgtcattctg gtcagattca actcttgggc
    29101 aacccgacgt tcttgttctg tttgtttact ttttttattg tagatttggc tcttctttag
    29161 aaaatcataa ttgtttttct ttggagcagg tgctgacact tcttcattct tggtagggat
    29221 agaatgaact tcttccgcca agatataatg agactgggtc aatttttggc tatatttgac
    29281 aaattcacca ggattttcct tttggaaagg agttgtcggt tgattgccct gtctaactag
    29341 actgggctga gaatgacgtc tcgcaaggct gaaatcctga gttaggtagt tagcagagcg
    29401 tttctttttc aagtccgcac gcgcttcttc acgcgccacc tccgcatagc tctttccttc
    29461 ttttttaacc cctaaaggag cctttttagg tttttcgact tgcttttcaa tcggttttac
    29521 tggtttttct tcagtaatag gagcccattc taaataattt ttatctcgat actcaccctt
    29581 gatattactg atcagatcag actcatcata gagattcatg actggcattt cagtcaacat
    29641 gacctcgtca tctgacacca atggaaatcg ttcttgtttc attttctatt tcctttcaac
    29701 acttcattat agcgtattgt cttgattttt caagtgctgg cttcagaaat tcccaaaatt
    29761 tctctaattt ctgctagggt cagactacca cgtgactctg tgccatccaa tacttgtgac
    29821 accagatgtt tcttttgttc ttggagttcc tgaatttttt cttcaatggt tcccttggtc
    29881 accaagcgat agacctcaac cgtttcttcc tgacccatcc gatgggcacg gccaatggct
    29941 tgcgcttcca ccgcaggatt ccaccaaagg tcaaccaaga tcactgtatc tgcacctgtc
    30001 aggttcagac cgaccccacc agccttgagg gaaatcagaa aggcatctct ttctccttgg
    30061 ttaaaggcct tggtcatgtc ttgtctttcc ttggctgggg ttgaacccgt aattttaaag
    30121 gatgtcaggc ccaagtctgg cagttcttgt tcaatttttt ccaacattcc cttgaactga
    30181 gagaaaatca agacacggtg tccgccgtct gccacctgta ccagtaggtc tcggagacta
    30241 tctagtttgc cgctggctcc ctgataatct tccataaaca gggcaggagt gtcacatatt
    30301 tgacgcaagc gcatcaaacc agataaaatt tccacacgac ttcgctgaaa ttcctgttct
    30361 gacacttgag ccagatggtc tcgcatctgt tgtaactggg caaggtaaat agccttttgc
    30421 tggtcttcca gttcattttt ataaaccacc tcaatcaagt ctggcaattc agtcagaact
    30481 tcttctttct tgcgtcgcat cacgaaaggc ttgataaact gagccactcg ctctgctggc
    30541 aatttcataa attctttctt gcttggcaaa agtccgggca tgacgatttg gaaaatagac
    30601 cacaactcac ccagatggtt ttcaatcgga gttcctgaca aggcaaagac cgacggcacc
    30661 acaaattgtc tcaaggtctg ggcaatcttg gtctgggcat ttttcatgac ctgagcctca
    30721 tctaagaaaa ggaagtcaaa ggccatcccc tgataaaact cactgtcctg acggaaggtg
    30781 gcatagctag tcacatagat ttgatggctc tcggcaagaa tctcctcacg acttgctttc
    30841 aaaccatgaa caacagccac atccaactgt ggggcaaatt tctgaaactc atctgcccag
    30901 ttgtaaatca aacctgacgg agcgagaatc aaaacccgac tttcttttgt cacttgacta
    30961 gtcaaaaaag caatggtctg aagggttttc ccaagtccca tatcatcagc caaaatccca
    31021 ccaaaaccat aatgatggag catctgcaac cagccaattc ccttttcctg ataatctcgc
    31081 aagtcagcct gaacctgagt tgcctgtcga ggaaagtcct ctggatgtgt caaatcctgg
    31141 gccagattct ggaattcttg tgaaaaagaa acacggtctc gcccttcaaa gagatgagct
    31201 aaactgtagg ccaaggattt ccgagcctgc aaggtcccat cttttaattc aaattgcccc
    31261 agttcctgta gattttggcg aattttcttg gtttcttcat cgaaaaagta aacttgatta
    31321 gacgaatcaa tataaaaatc ctgattggca accaagacct gcatggcttg gtcgatttcc
    31381 tcctgggcaa tatcttgaaa atcaaactgg atttccaaga gacctccctt ggaggcaatc
    31441 tgcacctgag gactcgctag gctataaagc tcttctagtt tatctgatag gtcaacatgc
    31501 ccgagttttt caaagactgg aatgatatca tgaaaaaaat gatagacaga ctccgctttt
    31561 aaggcctgac gccaagattg aaaatcggct tcaaagcccg cagccaaaca gacttggaaa
    31621 attctttctt ctaagtccgc gtcacttgaa aatggtaatt cttctagctc ttgtcggcta
    31681 gatacctgtc tatttccata atcaaactga atttctaaac gaatccgatt atcttcttcc
    31741 ctgtcaaagt aaaaagaggg cgcaaaagtt ttgatttgta gacgttctgg agctgaaacg
    31801 gtgcccatct ggataaaaag agtcagacag gaggccaatt tgtctcgatc actgctatca
    31861 aattgcaggt atttctttcc ttgttgaccc acaggtaacg ctttaatttc cttgagaaga
    31921 cgcatctgct ggtctgttaa aaaataaacc tgacctttat ggaaaagtac tgctccctga
    31981 taaaagacat tgaccctagg actctcactg atttccattt caaaatagtc cgagtattct
    32041 gttactgtaa aggcaaatag attggcatca gcatgcatat cctgaaaaag cagggtttgg
    32101 tagctatcca cttgatggtc aaattgaaaa tggggcaagg ccatcagtaa attcacaccc
    32161 tgctcaaaaa aggtcagagg gaaaaagagg tgccgacctt ggttttggaa aaagaggtct
    32221 gaaaccagcc cttcctccgt tagtccgtgc aagaaagtca aaagttcttg gctggcatca
    32281 tcaaaggctt cccaagaaag agactcctca taaatcttgc caatcatata cgactttctc
    32341 tgctcgacaa tccttaaaaa aagtggaata tcccgaatga catagtattt ttggctattg
    32401 atttggccga ttctcagagt ccacaagata tgattggttc ctgcttccac ctgacccaca
    32461 gctgataact cataggcgca ttctgatttt ggagataaaa ttcgatccaa aaacttgcca
    32521 cccaaggtta ccttggtttc aacagcctct ttttcttcat gaccttcttc cagactccac
    32581 aagatttcct gaccacgctc atcatttttc agaaaatgct ctagcgctgc caaatgcaca
    32641 cagtaacccc tcttttgaaa aaaatcacag gcacaaaaaa ccaaatcatc ctctaaacta
    32701 tagcgcagtt cttcttctgc aacgcgagcg tagagccgat tgttcttttc cttgatgata
    32761 tcaaccttac cagtttcata aagggcaaca ccttcgatac gaattttccc cggaatcaat
    32821 ttagccatat tttcaccttt accttatctt tttattatac catattttcg cctatgaaaa
    32881 tagccttcta ggaagacttt tctcctagaa ggctggattt ttaacgtttg gcaaaagtag
    32941 ccacaatccg ctgacagact tcttgcaaca gagatttggg catagctata ttgatgcggg
    33001 catggagact tccttcctct ccaaaatcca aaccacggtt gaggataacc ttggcttcat
    33061 ttctcaacaa ctcttgcaat gtttcatcag tcaggtcata agctgaaaag tcaagccaaa
    33121 tcaagtaggt accttgcggt ttcatgacct tgattttagt ctcttttcca aatagatcca
    33181 ccacataatt gatgtggtct tcaaagactt gcttgagttc ctctagccaa tctttaccgt
    33241 atcgataggc agcttctgtc gccaaataac ccaagcctga aatttcatgc tgattattgg
    33301 ccaacaggcg tttctggaaa gctagtctca acttaggatt ttcaatgact gcataggaat
    33361 tttttgttcc agcaatatta aatgttttag tggcactgct caagacgata gcaaaatttt
    33421 tgaaggcagg attgatggta ttgaaagact ggtgtttgtg accaaagagg gtcaaatctt
    33481 ggtgaatctc atccgaaact aacaaaacac cgtgtttttg gcagagttgg ccaatcttct
    33541 ccaacacttc tttttcccaa acacgtccac caggattgtg agggttgcaa agaatataga
    33601 gtttaacctc ctcttccacc aaatcctttt caagttggtc aaagtcaatc tcaaacagac
    33661 catccttttc cactaaggaa ttagtaatca atctacgatt attcaacttg acactgcgag
    33721 caaagggtgg gtagacaggc gtgttaatta aaaccgcctc gccttctttt gtaaaggttt
    33781 gaatagctgt tgagatggct ggtaccacac cctcgataaa gacaagagcc tctttgtcaa
    33841 agttgtaacc gtattgtgta gcttcccact tttgaacttc cttaattaag tcttcactgg
    33901 cataggtata accataaacc agttggtctg cgtaaatttg cacggcttgg cggatttcag
    33961 gcaagaccac aaagtccata tccgctatcc aagctggtag aacttcacta tccgtttctg
    34021 tttctttcca tttataggta tggtgcccta aacggttggg caggcttgta aaatcatatt
    34081 ttcccatctt tgtcttatcc ttctaaggct tggcgcaaat ctgcaatcaa atctctagca
    34141 tcctcaatcc caatagacaa acgcaagagg tcatctgtca aaccataaga atggcgtact
    34201 tctgctggaa tatcagcatg agtttgagtc gttggataag taataagact ttccactccg
    34261 cccaaacttt ccgcaaaaga gaagaccttg agactgttca aaatatgagg aatgcgtgtt
    34321 tcatcggcta ctttaaagga aatcatgcct ccacgaccag tgtagagaac ttccttaact
    34381 gctggagaat ccttcaaaaa ggcaaccact tcttgggcgt tagctgttga gcgctccata
    34441 cgaagagaca aggtcttgag accacgaagc aactggtagc tgtcaaatgg agacaagact
    34501 gcccctgttg tattgagatt gtaaaaaagc ttctcgtata gttctaaact attggtcaca
    34561 accactccag ccaagacatc attgtggcct gctagatact tggttgctga atggagaacg
    34621 atatctgctc catcttcaat cggacgttgg tagatagggc tatagaaggt attgtccacc
    34681 accactttgg cacccttagc atgagccaat tttgctagtt tttcgatatc aaattccaac
    34741 atcaagggat tggttggggt ttcgatatag agaacatcca catccttttc taactcggca
    34801 atcaactctt cttctgtatt ggcataggta aaatggaaac gaccttcctg ctccacttgg
    34861 ttaaaccagc gaaaagaacc gccgtaaaga tcacgcactg ccaagacctt acttcctact
    34921 ggaaagccgc taaaggccag tacaatagct gacatccctg agctagtcgc taaggcatag
    34981 tctgctgact caatagtcgc caagacttcc tcagccttac tacgagttgg atttttagtg
    35041 cgcgtatagt caaacccagt agatcgacca aactctggat gctgataggt cgttgaaaaa
    35101 tgaagcggtg tcaccaatgc acctgtcgct tcatctgact taatacccgc ctgggccaaa
    35161 attgtgttaa tgtgtaattc cttgctcata caatacctcc aaatctatag taactattgt
    35221 accacttatt ttcatcaact cattttcttc ttttcaagag ctagttatag tttcaaacta
    35281 tataaaaagg gagtttttcc tgctcccttt aatagactat aaaatggtga atctcaaaag
    35341 acacttcact ctatcatttg ctcctgcaca aaacaagcat aacgctcatg attttccagt
    35401 agttccttat gagttcctga gccagtgatt ttcccctcct ctaagaagaa aatacaatcc
    35461 acatctttta ccgttgacaa actatgcgct ataatcacaa ccgtcttctc ctttaataca
    35521 gaatagaggc tactgataat cgcatactca gaatccgcat caagattagc agtagcttca
    35581 tcaaatataa gaatttcagc atcttttaag taggttctag ctatttgaag tctttggctt
    35641 tgcccccctg acaagaatcg tccgcgttca ccaacttcag tatctagtcc ctctttcatg
    35701 gagcgaatct catcacctag tgatactaag tctagcactt tcatcaattc atcatcagtt
    35761 actaagcgat tcaaaccgag acaaagattg tcacgaatac tgccagataa gactgcatta
    35821 ttttgtgaaa cccaagcgat tttacttctc cattctttta agttaaaatc atatatactt
    35881 gattgctcca ttagaatatc tcctgaaagc ggtttataaa accgctctaa caaacgcaca
    35941 atcgttgatt ttcctgatcc agatggtcca acaaaagcaa tttttgcccc ttgaaaattg
    36001 aacaagtaat atcctttaag acaggtcgat tttcatcata accaaaatag acatggttaa
    36061 aattcaaccc ttgtcctgat accgattttc ctccctcaaa tttttcttta ggaactgcaa
    36121 gcaagttatc cagtgcaact gaagatccct tgctcctaga ataaacagtt acaaaattag
    36181 ctatattact aataggatta agtaattgaa agaggtaaat caaaaacgaa accaaggttc
    36241 ccacagatat atatcctgcg ctgacccgat aacccccata ggttagcatc acagctatag
    36301 tcgcaaagat aaataagaga gcaaacgggg tctcaaaaga agtaacccta tctgatttca
    36361 gtgaattgtt ttgtaccctt tcaatacaat tatccaaaac atcctgtaca cttttctctg
    36421 cttggttagt cttaattaat tcatgttctt gaatcttttc agtcaattgc cctgttaaat
    36481 ttcctcctgt aaacgacgac tatacttttc actgatattg gaaaggggca agataataaa
    36541 catcatacaa ggaagagtga tgaataaaag tagagaaaga ttccaatcaa gactaaataa
    36601 gactacaatg gaaccaagta ccataactaa actcagaata atatttggga aagtcgtaat
    36661 taaaaactca cgaatgacac tcatgtcatt gacaatggca gaagtcaact ccccactttg
    36721 gctcttatca aagaaggatt tctctgcata aatcaacccc tctatcactt ttttcctgat
    36781 ttttgctatc tttttttcac ccgattgact aaacagatag taaccaatag aagaaaacaa
    36841 ggcttgacca atacgattga aatactttgg aacctatatt ttcaatagaa ctcccatcta
    36901 ttaaaccctt taagataagg ggaagcaaca aagcaagtag actagacaga acaagtaaga
    36961 aactccccat aatcacctta gtatctactc ttaataattt taatttcata aatactcctt
    37021 ataatatttc aacggataaa gtcgggaata actcaatttg aggataaaat ctaataaatc
    37081 ttcctataac aaaacgcata acatctagga ttttatatac ctgatattat gcgtttttaa
    37141 gcacaaagac ttcttacaca aacttatcta caattagatt ttatttgaca tgttttgcca
    37201 attcttcttg ggctttttta ttggattctt ctttttcttt caaccatttt tctctggctt
    37261 ttgcatattc gtctgttgtg acaatcttat cttgtacttt gaggtattta tatgattcaa
    37321 ccccttttgt accggttaaa ccataggcag cagcaaatgg tacggttctt ctcaatgatg
    37381 gtgttccccc acgcgaaaca cttggaagaa ctaaagaact atcaatcaac caagcttgaa
    37441 tatcagcata tttctcataa cgtttggctg gatcttgctc tttattagct tcttccaaca
    37501 tttgagtata gacatccagt ccaactgcct tagccttgtc attggcttct ccaggctcta
    37561 gtccaagatt ttgtagaact cctccactat tagtattaaa aatatcgaga taggctgacg
    37621 ggtcttgata atcaggtccc caaccgccat gatataaatc atagtctttc tgagcagctg
    37681 tttgagcaaa gtagcctgaa ctgtcaaact catctgatgt taattgctga atgtcaatca
    37741 ctacattatc agaacctaaa acagattcaa ttgattgttt gatagaacta actccttgta
    37801 tgcctacttt atctgttact tccacagtct tatccaagtg gattgggaat tgaacaccct
    37861 ttgcttcgag ttctttctta gcttccgcaa acttagcctt ggctttctca ggattgtagt
    37921 aagggtcttg accatccgca aagttgatac cttgccattc cttaccatag ttgaccatct
    37981 tagaggctac aacttcacca aagtcttttc ccttgatact gacaaagttt ggaggaacca
    38041 ctaggttacg caaaatcttt gttgcacctt ctttcccttc agactgagcc ccataagatg
    38101 ttctgtcaaa agcaaaattg atagcctgac ggaagttttt attgagaact gcttcctggg
    38161 tcgatttctt ttcaatgtca cttgttttag aagtataatt gtaagacttc ctatctaggt
    38221 taaaattaaa gaaatatgaa gttgaatttt gcatactata gatgatattg tttttgtatt
    38281 tttctttaat cccttcatag ctggagctgt taggaaaaag acgagccgta gtataagcac
    38341 cagctgtaaa attacgttcc agtgattctt ggtcgctacc atcatagtag gtcaatttca
    38401 catcgtctac aaagacattc ttagcatccc agtaattagg gtttttctta tattcaatag
    38461 cagattttga gacaagtgct ttcatcaaga aaggtccatt gtacaaaata ctagatggat
    38521 ccgccttccc aaaatcatcc ccttttgatt tcaggaaatc tgcattaaca ggaaaaagta
    38581 tcgttgcaag tgtttttgaa ttccagtaaa gttctggttt aaccaaagta tattgaaccg
    38641 tttggtcatc aagtgccttg acaccgacag ttgaaaagtc gcttgtttta ccagtgatat
    38701 agtcatccaa accagcaaca gagtcctgca ctagatacaa agcttctgat tttttatcag
    38761 ctgcatattg caaacctgtc acaaaatcct gggcagttac aggcgcatat tcttctccct
    38821 cagaagtaaa ccacttggca tccttacgaa gtttgtaggt ataggtcaaa ccgtcctgag
    38881 aaacagtcca atcctctgct aatgatggaa taatattccc atattggtca ttttctaata
    38941 acccgtctac caaatttgca acaatatcgg atgttgctgc gcggttttct gctagatagt
    39001 tcaaactaga tggatcactt gaataaacat agttataggt ttttgatgca gtgctagaat
    39061 ttccacacgc gctcaataaa actcctgtac ccaggacaag acctgccaag gttagatatt
    39121 tgctcttaga ctttttcatt tccagaacct cctgctttaa atatttgttt tattatacaa
    39181 ctcttggttt gtttagtcaa ttgttttttc caaaaaatca aaaaaacctc attttctatt
    39241 tttgaaagat aattttagct attttgacgc taaaaaagga ataagtttca agttctccta
    39301 aaagattgtt caacttattc cttttattta taaatgctac cttacgaaag cttaaatttt
    39361 gctcgcaggc gatctgcttg ggcttttcct attaccttat ctaataaata ggtacgcaga
    39421 ctcataacca tataaagtcc accccccatg gcaccgacaa gagctacata aaagaagctc
    39481 cacaaacgtc cacttggttg gaagaaaaat cctaacagcc actggatggt tcctattaac
    39541 agaaacatga ctagggtcag caaactgatt aaaatggttc gcttcaaaat caccttgcgc
    39601 ttgacaccag ttactttaca aatatcccga tacatcaaga cgttaggaat gatgagagca
    39661 atggttgttg aaatcaaagg accataactg tggaagaggg cgatggtagg tagttgcaag
    39721 actagcttgg caatagaacc atagataaaa tagagaacgg ccttgcggtt gcggaacatg
    39781 gcctgaagca ttggagacaa gaccatgtac aagcctaaaa taatagactg caaaactgca
    39841 aagacaaata agcccagagc caaactatct ggcttaccat agaagaccgt ataaagaggt
    39901 tctcctacca taaccactcc aaccgttgct ggtagcaaga acataaagag tagggtgaga
    39961 ctgtcctgaa cgagacgaga agccgctttc aagtccccct tgacatagtt ttccgtcaaa
    40021 agtggcaaac caacactccc aatcgaaacc cctacagaaa tcaaaatcat cgtgatttta
    40081 ttaggattgg ctgagaaata agaaaacatg acaaccaagt cctcattgct gtagttggta
    40141 aaccagctca tactattgat aaaggtcagc tgatccaaaa tctggaagag ctggatggca
    40201 gaccctgtca ggataaaagg aatggcttcc ttaatggtat caaccaagag acgcttactg
    40261 ttaatcttat ctcctgtttc aaagactctt ttgagtgaac cttcttgggc aaggaaataa
    40321 atcaagactg caaaactggc taccataccg acaaaggcag caaaggttga ttgggtaacg
    40381 gctgctagat aatctcctga accgagcttc ataatgataa aggttgctag gagcatccag
    40441 ataacacgaa tgacctgctc agcaatttgg ctcatggcat agggtttgag gttattcatc
    40501 ccttggaaaa atcctcggat aacactcata gacgggaaaa tcaagactcc ccaagccaag
    40561 ctttgcatga ttgggatcaa gtctttgccc acgccagaca agtctgctag ccaaggagca
    40621 aagacataca agactaaagc aaaaaccagg cctagtcctg tcataaagcc taagaagctc
    40681 cgaatcaggg caaagctatg ctcttcttct cgcatggtat tatacttggc aacttgcttg
    40741 gccaccgcaa ctggaatccc cgctgttgaa accaacaaga accaagcata gatattgtaa
    40801 cccatggtaa agagaccatt tgccttagct gcataagccc ccatccagat gtaccaaggg
    40861 ataatgtaaa cagccccgag taggcgactg ataaagttac tagccgttag ccaagcagtc
    40921 ccccgtaaca tctgggcctg ctggtgattg ttttcgtgcg acatagattc ctcattcaat
    40981 tttgataact aggaaaaact ccttatcttc cattataaac ttttccttgt tacttgtaaa
    41041 tttacgactt tcggtttaca atagaaagta tgattaagat tgaaaccgta ttagatattt
    41101 taaagaaaga tggccttttt cgcgaaatta ttgaccaagg tcattaccac tacaactaca
    41161 gcaaagttat ttttgatagc atcagctacg acagccgaaa agtaacagaa gacactcttt
    41221 tttttgcaaa aggcgctgcc tttaaaaaag aataccttct ttctgctata acacaaggtt
    41281 tagcttggta tgtagctgaa aaggactacg aagtcgatat ccctgtcatc attgtgaacg
    41341 atataaagaa agccatgagt ttgattgcca tggagttcta tggtaatcca caagagaaac
    41401 tcaaactcct tgcctttact ggtactaagg gtaagacaac agcaacctat ttcgcctata
    41461 acatcttatc tcaagggcat agacctgcta tgttgtcgac catgaacaca actcttgatg
    41521 gcgagacttt ctttaagtca gcgttgacaa cccctgagag tattgacctc tttgacatga
    41581 tgaatcaggc tgtgcaaaat gaccgtactc acctcatcat ggaagtctcc agtcaagcct
    41641 atctagtcca tcgagtctat ggactgacct ttgatgtggg agttttccta aatatcagcc
    41701 cagaccatat cggcccgatt gaacacccta gctttgaaga ctatttctac cacaagcgtc
    41761 tcttgatgga aaatagccga gcagtcatca ttaacagtga catggaccac ttctcagtct
    41821 tgagagaaca ggttgaagat caagaccatg atttctatgg tagccaattt gataaccaaa
    41881 tcgagaattc caaagccttt agcttttcag ctacgggtaa actcgctgga gattatgata
    41941 tccaactcat tggcaacttc aaccaagaaa atgcagttgc tgctggactt gcttgtctcc
    42001 gtctcggagc aagtcttgag gacatcaaaa aaggcatcgc tgcaacccgc gttcctggtc
    42061 gtatggaagt cctcactcag aaaaatggag ccaaggtctt catcgactat gcccacaatg
    42121 gggatagtct gaaaaaactc atcaatgtgg ttgaaactca tcaaaccgga aagattgctc
    42181 tggttctggg atcaacagga aacaagggag aaagtcgtcg taaggacttt ggcctcctcc
    42241 tcaatcaaca ccctgagatt caagtctttc tgactgctga tgaccctaac tatgaagacc
    42301 caatggccat tgcagatgaa attagtaact acatcaatca tcctgttgaa aagattgcgg
    42361 atcgccaaga agccatcaag gcggcaatgg ctatcacaaa tcacgaatta gatgcagtta
    42421 ttattgcggg taagggagcc gattgttacc aaatcatcca gggcaagaaa gaatcctacc
    42481 caggagatac agccgtcgca gaaaattatt tataagaata gaaaaaatca agggaaaatg
    42541 aaacccttga ttttttccta ttctttagta aaaacgtttt tcaaaccttc aacggcacct
    42601 tctacagcac cttttgcgtc ttctacaacg tcttttgcct tagcaactgt tttttcaaca
    42661 gctccttcaa gttctgtctt gctgtctcca gtaactttac caaaaccttc tttgacagcg
    42721 cctgttgctt gttccaattt gttttcaagt gacatatgat tgtctccttt agtttattcc
    42781 gatatgtgtt accggttaca tatagtttat accgaatact aaggaaagtc aaacaatgtg
    42841 ctcagaaaca agaaatcacg ctaagtagaa agttaatctc tccttatcaa aatcgatagc
    42901 caactcatac tttccatctt cattttgcac aatatagcct aagacaacca aactgtccac
    42961 aaagatatca cggcatttct gcataagctg gtattttttg agaaatttca acaaaaaagc
    43021 cgtcatatac ttgagggcat actcaggatt aacatctcct aaaatgtcat agagctcctg
    43081 ctgtttttct gtcaaaggat actgctgttt gaccttgtaa aaataattgg acagggtcat
    43141 tttaatgcgc gcaaagtccg tcttttcaac taaaatagct gcattgattt gattgcgcaa
    43201 ttccgtctca aaactctgct ccaacaaggc ttgatagacc ggactagctt ctctgacaaa
    43261 aatctcttga tccagttcaa gactatcaag tgattcaagc gtaggaaaat tgaggtaata
    43321 gcgcttattt tcacgtagaa tcaagcctgc ctttatatac tcttccatga gtttatcaac
    43381 tgcaacatct ggaaattgag ccttaatttc ccgtagaatc acatcctcat actggtccag
    43441 atagcggatc aattctccaa aaatggctgt ctcgtcaaac gagatggatt aaaaatctga
    43501 atcatgaaga ttcctttctt tacattgtaa cagaggcgat gctgccaact gactaggatt
    43561 ggtaccagct tggttcagag gaacaggcag acctagttct atgtaatact ccctccaaaa
    43621 atcactaatc tcctgctccc catctccaaa tttcatagga atagtttcaa aaataggtag
    43681 gatttctgct atatactggg agcagtagaa accagctgca tctggataga aagaagcatt
    43741 gtagggtgct ccaagatgtt tgcaagctct ttccttcacc gactggatat ccatttctgg
    43801 gtaaacatag aggtcgtata aatgattgga ctcaaagaag tctgccggtt cttgacagac
    43861 aacaccagcc tgtccactag catgataaat catcccatcc aaataaatgg caacatggct
    43921 atagttacct gtggaagtct ggatggcctg tcccatgtct gacccatctc tcacaaaaat
    43981 caaatcgcca ttttctaaca tacttcactc ctagaaaaaa ggagccgaaa ctcctttcga
    44041 tataaggcaa actagacttt ccgattttga gctgacaccc aaaatcttac gcattaaagc
    44101 tttcagtcaa ttgaggtacc acttgtttct tacgtgaaac ggcaccagca aggaaggcat
    44161 gattgttttc aagtttgaag ttgaaagccg cttcgacctt gtccatattg gcaccaagag
    44221 ccaagatttc tgagtttgag ttgacgatat ctgtaatcat caagacaaag tcagagtagc
    44281 cgtttgattc gttggcagct tgcattgcag cttcaatttc tgcttggcgt tccaaaactt
    44341 cagcgatgtc aactgtgttc acttgggcaa cacggacatt atttccgttg agttcaaaag
    44401 ttttagcatc gatgtcaatc aattcttcag cagatttgct agccaagttg gtaccagctt
    44461 tcaacattgc caaaccatat tcttccaagt tcacaccagc caattcagcc aattcaggag
    44521 caatgatttt atctgttggg tgtgttgttg gtgatttcaa aagaagggta tctgaaatca
    44581 aacctgaaag catcaaacct gcaatctctt taggcacagc tacaccatgt tctttgaaca
    44641 tacggtaaac gattgaagac gctgatccaa ctggctccaa acgcatgtaa agtgggcttg
    44701 cagtttcaaa gttagccaca cggtggtggt ctacaacacc gtaaacttct acttcagcga
    44761 tatctgatac agattgttgg aattcattgt ggtcagtcaa gataacttgc tctgccccct
    44821 ctgctttggc agaagtgata acacgtggtg cttccacacc aaaatagttc aagacaaagg
    44881 ctgtttcttc atttggagtt ccaagggcaa cagcttccgt atccaaaccg taagcttctt
    44941 ttgcaaggta ggcaaaagct acagatgacc cgatggcatc tgagtctgga ttttggtgac
    45001 caaatactag aatcttggac atgataatac ctcattttgt ttattttctt tattgtagca
    45061 tttttttcgc tttttgacaa aggtaagagg agtcaaagga ctccccacga ttcttcaaaa
    45121 taactgagta aatttctatc ttgattttca gataaaaatt cttccttctg tggcctcttc
    45181 ttacgcttga gaagagcttc agccgacatg gcttcttcct tactggcaaa accttgagca
    45241 tagataagtt tgactggcaa gcgtgctcgt gtatatttgg ctcccctccc actattgtgg
    45301 atagcgaggc gtcttctcac atcagtcgta tagcctatat agtaggatcc atcacgacac
    45361 tccagaacgt acatataagc cttatgatcc ataataaatc tcttcgattt cgggcgtata
    45421 agagccatca tcattgtgga caatcaaagg aggtaagacc ttaaagccac ttgttgagcc
    45481 atccttgatc gcctcaatca aaagcatatt ggcttccttt tctctttttg gataaacaaa
    45541 ctgcaggcgc ttaggggcta gattatgtcg ttttaacgta tccaaaatat ccagaagtcg
    45601 atcaggacga tgaaccatgg ccaaacgccc attagacttg agaatactct gagcactacg
    45661 acagatttct tccaaattag tcgtgatttc gtgtcgagcc aagagataat gttcactctc
    45721 gttcagatta gaataaggat ccaccttgaa atagggtgga ttacacaaaa tcatatccac
    45781 cttactcccc tgaatgtgag caggcatatt tttcaaatca tcgcagatga cctgcatttg
    45841 ctcctctaat ccattcaaac ggacagagcg ttcagccata tccgccaaac gctcctgaat
    45901 ctcaacagac aatatctgtg cttgagtacg agtgctagca aaaagcccca ctgctccatt
    45961 cccagcacag aaatccacaa tcaacccctt cttaggaaaa cgtggaaatc gtgataagag
    46021 aacactatcc accgaatagc taaaaacctc tctattttga atgattttga tatctgtcga
    46081 aaagagctgg ttaatgcgct ctcctgattt taataattgt tcttcttcca tggtcctatt
    46141 atagcaaatt tatattaaca ttacaaaaaa tataaaactc taaactactt cttctttttt
    46201 aaatggtgca gggcttctcc agtccagatt ggtaacattc gtcgaaaggg agcaaaaccg
    46261 tagttaaagc ggtcgcttga aaagcgtctc cgtctaggaa actggtactt ttcttcctcc
    46321 aaagtgcgga tagaaagact ggctttcccc gtaaattcat ctaaatccac tacctgaact
    46381 tgaacctctt catcgacttt caaggtttca tgaatatttt caataaatcc tgtccgaatt
    46441 tctgaaatgt gaatcagccc cgtatcaccc gtctctaact caacaaaggc accgtagggc
    46501 tgaatccctg taatacgccc ctttagctta tcaccgattt tcatcttagt cctcgatttc
    46561 aatagtttca attacaacat cttcaactgg cttgtccata gctcctgtct caacagcagc
    46621 aatggcatcc aagacagcgt aagatgcttc atcagctaac tgaccaaaaa ccgtgtgacg
    46681 gcggtctagg tgaggtgtcc caccttgatt ggcatagatt tctgcaatcg gttctggcca
    46741 accaccacga gtaatttctt tcttcgaata aggtaggtgt tggttttgca cgataaagaa
    46801 ctggctgccg ttggtatttg gaccagcatt tgccatggaa agagcaccac ggatattgta
    46861 aagctcttct gagaattcat cctcaaaaga ttcgccgtag attgactcgc cacccatacc
    46921 agttccagtt gggtctccac cttggatcat aaagtccttg ataatacggt ggaaaatgac
    46981 accatcatag tagccatctt ttgaaagaga tacaaagtta gccactgttt taggagcatg
    47041 ttcagggaaa agcttgatac gtaagtctcc gtgattggtc ttaatagtcg caagaggacc
    47101 ttctactgtt tcaatgtcta cttgtggaaa atgcaattct ttttctacca taccaaatac
    47161 ttctaaggca tcaaaaatgc catcttcttc taatgttttt gtaatataat ccgctttttc
    47221 tttgatttta tcatgagaaa ttcccatggc aacgctgatt ccagcataat caaagagttc
    47281 caagtcattg agaccatctc caaaaaccat gaccttctct ggtttcaagc caaggtgttc
    47341 cacaaccttt tccacccccg tcgctttgga gcctgaaatc ggcacaatat cagacgaatg
    47401 ttgatgccaa cgaaccatgc gaagtttgtc tgagagactg tcaggcaagt gcaagtcatc
    47461 tcccttatct tcaaaagtcc acatctgata gatatcttct ttttcatgga aatcgggatc
    47521 tacatctaag tcgggataaa ttggattgat agcttcactc atcatatcgg tgcgagtcga
    47581 caacttggca tcatgactcc caaccaagcc atactcaatt ccttcttgct tagcccaaga
    47641 gatatactcc tcaacatctg acttttcaat ctgatgctga taaatgacct gacctttttt
    47701 atcttcgata taagctccat tcaaagttac aaaaaagtca ggcttgagat cacgaatctc
    47761 tggaacaaca ccaaaaatgc cacgtccaga ggcgattcct attaaaattc ctttttcacg
    47821 caactgttta aaaacagtgg gaattgtagt tggaataaac cctgtctttg aattccgcaa
    47881 tgtatcatca atatcaaaaa agacaatctt gatcttcttt gccttgtatc ttaatttcgc
    47941 gtccatctca ctacctcttt caatctaact ctttccatta tatcataaag taggcaaatc
    48001 ccctattttc aaaaagttta tcatttttat tttaatttct tggatgagaa aagagacata
    48061 tttatgaaaa agctccatcg tgcttttaat gtgttctctt gttttcaaac tcgtaaaaag
    48121 ggagccactg agcctaactc gctctctcat ttcaaagctt gtgaaaaaag acccgttggg
    48181 gtcttaattc gctttcttgt tttcaagctc atgaaaaaga gacccaaccg ggtcttttct
    48241 ttaatcttcg tttacgaaag gcatcaaagc cattacgcga gcgcgtttga tagctgttgt
    48301 tactttacgt tggtttttag ctgaagttcc tgttacacga cgaggaagga ttttcccacg
    48361 ttctgaaacg aaacggctaa gaagctcagt atctttgtaa tcaacatatt caattttgtt
    48421 tgctgcgatg taatcaactt ttttacggcg tttgaatccg ccacgacgtt gttgagccat
    48481 gttttttctc ctttataagt ttagttgtcc attagaatgg taaatcatca tctgaaatat
    48541 ccaatgggtt tgttgctcca aatggatttt cattacgtga aaagtctggt actgaatttg
    48601 taggtgctga atagtttgca gttggtgcag agtaagctcc acctgtgtga ccctcacgca
    48661 cactacggct ttccaacatt tggaaattct cagccacgac ctctgtcacg tagacacgtt
    48721 gtccttgctg gttatcgtaa ctacgagtct ggatacgacc tgtcaccccg ataagtgagc
    48781 cttttttagc ccagttagca agattttcag cctgttggcg ccacataacg acattgataa
    48841 aatcagcctc acgttcacca ttttgactct taaatgtacg gtttactgca agagtaaaag
    48901 tcgcaactgc tacatttgat ggggtataac gcaactcagc gtcacgtgtc atacgcccta
    48961 caagtacaac attgttaatc atagtttacc ttcttacgcg tcaattttga cgatcatgtg
    49021 acgaagaatg tcagcattga tttttgaaag acggtcaaac tctttaagag ctgcatcgtc
    49081 atttgcttca acgttaacga tgtggtaaag tccttcacgg aaatcttgga tttcgtatgc
    49141 aagacgacgt ttttcccaag tttttgattc aacaacagtt gcaccgttgt cagtcaaaat
    49201 agagtcaaaa cgtgctacca aagcgttttt agcttcttct tcaatgtttg gacgaatgat
    49261 ataaagaatt tcgtatttag ccattgatat gttcctcctt ttggtctaat gaccccaaga
    49321 ctttgcaagg ggtaagtgag gttcgctcac aataaactat tatactagaa aaaatttttt
    49381 tacgcaagta aaaacactag aattcgaaaa aacgccacat gggcgttttc ctgttcttat
    49441 ggtttgatac ggtgcaacat acgtgggaat ggaatagctt cacggatatg ttttgttcct
    49501 gctgcgaagg ttaccatacg ttcgataccg ataccaaatc ctccgtgtgg aactgtaccg
    49561 tatttacgaa ggtcaaggta gaattcatat tctgtacgat ccatgccaag ttcatccatc
    49621 ttagcgacaa gggcatcgta atcttcctca cgcatagacc caccgataat ttctccatag
    49681 ccttctggag caagcaagtc tgcacaaagc acgcgctctg gatttccagg aactggtttc
    49741 atgtagaagg ccttgatggc tgctggatag ttcatgacaa atgttggcac accaaagtgg
    49801 tttgaaatcc aagtttcgtg tggtgaccca aagtcatcac catgctcaag atgctcgtag
    49861 tcagcatctt catcattttc atgctcttgc aagaggtcaa tggcttgatc gtaagtgata
    49921 cgtttgaatg gctctgcaat gtagcgtttc aagagttctg tatcacgttc caaggtttcc
    49981 aaggcttgag gcgcgcggtc aagaacacct tgtagaagag ctttcacata agcttcttgc
    50041 aagtcaagcg actcatcatg tgtcaagtat gagtactcag catccatcat ccagaactca
    50101 gtcaagtgac ggcgtgtttt tgatttttca gcacggaaaa ctggaccaaa gtcaaagaca
    50161 cgaccaagag ccatagcccc tgcttctagg taaagctgac ctgattggct caagtaggct
    50221 ggcgttccga agtagtcagt ttcaaagagt tctgtagaat cttctgccgc atttcctgaa
    50281 agaattgggc tgtcaaactt cataaaacca ttcttgtcaa agaactcata agttgcatag
    50341 ataatagcgt tacggatttg caacacagct acttgcttac gagagcgtag ccacaagtga
    50401 cggttatcca tcaaaaagtc tgttccgtgt tcttttggtg tgattgggta gtcttgagat
    50461 tcaccgatca cttcgatgtc tgtgatgtcc aactcatagc caaatttaga acgttcgtcc
    50521 tctttgacaa tacctgtcac ataaacagac gtttcttggc tcaagcgttt gataacatca
    50581 aacttctcaa gtcccacttc ttcaccaaat ttttcgacaa agtttggttt aaaagccaca
    50641 ccttgaaaga aggctgttcc atcacgcaat tgtaagaaag cgattttccc ttttcctgat
    50701 ttgttggcaa cccaagcgcc aatcgtcact tcctgaccaa catagtcttt tacatcaata
    50761 atcgttacac gttttgtcat tatttttcct tttctttttt attctttatg gcaaaccacc
    50821 tctatattgt tcccatccag gtcaatcata aaagcagcat aataaatcgg atgctcactt
    50881 cgataaccag gaaccccatt gtctcgccca cctgcctcta agccagcctc ataacaagcc
    50941 tgaacttctt ccttattttc tgctaaaaaa gcaaaatgaa caggatcttg tgttccctga
    51001 gtcagccaaa aatcaccacc aggatgaggg ctgttcgggg atagaaaact aattagagaa
    51061 ctagtcttaa aagccaattt atagtccaaa ggagcgagaa aactcctata aaatccttct
    51121 gaaatttgta aatcctttac cttaatctca aaatgatcaa tcattctcac tacccataaa
    51181 tgctttcaag cgttcgactg cttctttaag cgtgtctagg tctgtcgcat agctgaggcg
    51241 gacattttct ggtgctccaa atccagctcc tgttaccaag gccacttcgg cttcttctaa
    51301 gatagcagtt gtaaagtctg tcacatccgt gtagcctttc atctccatgg cctttttgac
    51361 atttgggaag agatagaagg ccccttgtgg tttgaccact tcaaatcctg gcacctctgc
    51421 aaggagggga tagatggtat taagacgttc ctcaaaggcc tgacgcatgc tttctacagt
    51481 atcttgctca cctgatagag cctcaactgc tgcatattgg gctactgctg acggattcga
    51541 agttgtttga cctgcaatct tggacatggc agcgataatg tctgcttctc caacggcata
    51601 accaatccgc caaccagtca tggcataggt tttagacaca ccattgatga ccactgtttg
    51661 cttgcgaatc gcttccgata ggctagaaat cggtgtgaac tcatgaccat tataaaccaa
    51721 gcggccatag atatcatctg ctaggatgag aatatcattt tctacagccc agtttccaat
    51781 tgccaagagt tcctcacggg tgtaaatcat acctgtggga ttagatggcg aattcagcac
    51841 caaaaccttg gtcttgtcag tgcgagctgc ttctaactgc tctacggtca ccttaaagtg
    51901 attgtcttcc ttagcagaaa caaagacggg aacgccttct gccatcttga cctgatctcc
    51961 atagctaacc cagtatgggg ttgggatgat gacttcatca cctggattga ccacagccat
    52021 aaagaaggta tagagagaat atttggctcc cgcagcgact gtcacttgat ttgacgctac
    52081 agaatagccg taaaagcgct caaagtagct attgaccacc gccttaagct ctggcagacc
    52141 tgaggttact gtataaaaag aagcacgccc atctcgaatc gatgcaatgg cggcatcttg
    52201 gatatttttg ggagtagtga aatctggctc acccaaggtt agagacaaaa tatctctacc
    52261 ctcagccttc agtgctttgg cacgggctcc agcagccaaa gtcacacttt cttccatttc
    52321 taaaacacgg ttggatagtt tcataggccc tccttattga ccaatgctcc tgtttcaaaa
    52381 tctactagat aaaaatcaga tcctgactta acttcccaga ttggcttgtc ttgataacga
    52441 ccaaaggtta tcttgtcaat ctcgccagct cccttttcct tagaaaccgt ttctgctttt
    52501 tcttgtgaaa taccctgatt tagctgataa acgtaaatct tatggtcatc tttaccaatc
    52561 aggacagcaa gcgcttcttg ctgtttatta cgaccaagaa cgctgtaata agattccaag
    52621 ccattgtata aatcaacctg atcagccttc tctaatcctg catactgctg agctaatttt
    52681 tctccttcac ttttagctgt ttgatagggt ttcatgctaa gagaaaccat atacagaaag
    52741 gaagcactga taaccacaaa caaaatcgtc atccctagac catactgcca cagtagatta
    52801 ttttttgctt tgttttgtct ttttttcact cgtctatttt accatctatt aagctttatt
    52861 acaagtgaat ataagaa
//
LOCUS       DBERDS010000008        52760 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.008, whole genome shotgun sequence.
ACCESSION   DBERDS010000008 DBERDS010000000
VERSION     DBERDS010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 52760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.008"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(138..296)
                     /locus_tag="ACL73E_000556"
                     /pseudo
     CDS             complement(138..296)
                     /locus_tag="ACL73E_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            592..1898
                     /locus_tag="ACL73E_000557"
                     /pseudo
     CDS             592..1898
                     /locus_tag="ACL73E_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1987..2676)
                     /gene="rplA"
                     /locus_tag="ACL73E_000558"
     CDS             complement(1987..2676)
                     /gene="rplA"
                     /locus_tag="ACL73E_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGS0800578.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2884..3309)
                     /gene="rplK"
                     /locus_tag="ACL73E_000559"
     CDS             complement(2884..3309)
                     /gene="rplK"
                     /locus_tag="ACL73E_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGS0800579.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(3618..4334)
                     /gene="ldcB"
                     /locus_tag="ACL73E_000560"
     CDS             complement(3618..4334)
                     /gene="ldcB"
                     /locus_tag="ACL73E_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGS0800580.1"
                     /translation="MKKRYIVLSGLLAVTLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(4360..4821)
                     /locus_tag="ACL73E_000561"
     CDS             complement(4360..4821)
                     /locus_tag="ACL73E_000561"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS0800581.1"
                     /translation="MCLICQRIEWIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHHMETSVKLRFLEEMSLVQEAVAKTFKAEKMNIELLGNGDAHAHWHLFPRR
                     SGDMRGHGLNGRGPVWWVPWEEMAAEDCQVKSHELEQMIKALSDELEKYTV"
     gene            complement(4823..5860)
                     /locus_tag="ACL73E_000562"
     CDS             complement(4823..5860)
                     /locus_tag="ACL73E_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGS0800582.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPSQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVVLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(5958..7283)
                     /gene="brnQ"
                     /locus_tag="ACL73E_000563"
     CDS             complement(5958..7283)
                     /gene="brnQ"
                     /locus_tag="ACL73E_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGS0800583.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(7454..7741)
                     /locus_tag="ACL73E_000564"
                     /pseudo
     CDS             complement(7454..7741)
                     /locus_tag="ACL73E_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(7901..8479)
                     /locus_tag="ACL73E_000565"
     CDS             complement(7901..8479)
                     /locus_tag="ACL73E_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGS0800584.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFLLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8533..9933)
                     /gene="pepV"
                     /locus_tag="ACL73E_000566"
     CDS             complement(8533..9933)
                     /gene="pepV"
                     /locus_tag="ACL73E_000566"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGS0800585.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAVRLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9946..10551)
                     /locus_tag="ACL73E_000567"
     CDS             complement(9946..10551)
                     /locus_tag="ACL73E_000567"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGS0800586.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIADRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10722..11522
                     /locus_tag="ACL73E_000568"
     CDS             10722..11522
                     /locus_tag="ACL73E_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0800587.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11704..12501)
                     /locus_tag="ACL73E_000569"
     CDS             complement(11704..12501)
                     /locus_tag="ACL73E_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0800588.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNVIEVEDGELVNILFRKVAYDYEAELEFAK
                     SKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(12491..14338)
                     /gene="uvrC"
                     /locus_tag="ACL73E_000570"
     CDS             complement(12491..14338)
                     /gene="uvrC"
                     /locus_tag="ACL73E_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGS0800589.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     GVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNEP"
     gene            complement(14377..15078)
                     /locus_tag="ACL73E_000571"
     CDS             complement(14377..15078)
                     /locus_tag="ACL73E_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGS0800590.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(15157..16389)
                     /gene="murN"
                     /locus_tag="ACL73E_000572"
     CDS             complement(15157..16389)
                     /gene="murN"
                     /locus_tag="ACL73E_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGS0800591.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(16394..17614)
                     /gene="murM"
                     /locus_tag="ACL73E_000573"
     CDS             complement(16394..17614)
                     /gene="murM"
                     /locus_tag="ACL73E_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGS0800592.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQTIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17726..18505)
                     /locus_tag="ACL73E_000574"
     CDS             complement(17726..18505)
                     /locus_tag="ACL73E_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0800593.1"
                     /translation="MAVMKIEYYSQVLDMEWGMNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18574..20235)
                     /locus_tag="ACL73E_000575"
     CDS             complement(18574..20235)
                     /locus_tag="ACL73E_000575"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS0800594.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(20410..22632)
                     /gene="recJ"
                     /locus_tag="ACL73E_000576"
     CDS             complement(20410..22632)
                     /gene="recJ"
                     /locus_tag="ACL73E_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGS0800595.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIAFMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGMVQEIYDFLMEKE
                     "
     gene            22909..23667
                     /locus_tag="ACL73E_000577"
     CDS             22909..23667
                     /locus_tag="ACL73E_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0800596.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            23678..24472
                     /locus_tag="ACL73E_000578"
     CDS             23678..24472
                     /locus_tag="ACL73E_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGS0800597.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24485..25162
                     /locus_tag="ACL73E_000579"
     CDS             24485..25162
                     /locus_tag="ACL73E_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0800598.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            25172..25831
                     /locus_tag="ACL73E_000580"
     CDS             25172..25831
                     /locus_tag="ACL73E_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0800599.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            26089..27279
                     /locus_tag="ACL73E_000581"
     CDS             26089..27279
                     /locus_tag="ACL73E_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGS0800600.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTIKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27600..28481)
                     /locus_tag="ACL73E_000582"
     CDS             complement(27600..28481)
                     /locus_tag="ACL73E_000582"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGS0800601.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28622..29950)
                     /gene="vncS"
                     /locus_tag="ACL73E_000583"
     CDS             complement(28622..29950)
                     /gene="vncS"
                     /locus_tag="ACL73E_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGS0800602.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMYLDAQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29947..30603)
                     /gene="vncR"
                     /locus_tag="ACL73E_000584"
     CDS             complement(29947..30603)
                     /gene="vncR"
                     /locus_tag="ACL73E_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGS0800603.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30652..30735)
                     /gene="pep27"
                     /locus_tag="ACL73E_000585"
     CDS             complement(30652..30735)
                     /gene="pep27"
                     /locus_tag="ACL73E_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGS0800604.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30915..32294)
                     /gene="vex3"
                     /locus_tag="ACL73E_000586"
     CDS             complement(30915..32294)
                     /gene="vex3"
                     /locus_tag="ACL73E_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGS0800605.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(32346..32993)
                     /gene="vex2"
                     /locus_tag="ACL73E_000587"
     CDS             complement(32346..32993)
                     /gene="vex2"
                     /locus_tag="ACL73E_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGS0800606.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(33006..34283)
                     /locus_tag="ACL73E_000588"
     CDS             complement(33006..34283)
                     /locus_tag="ACL73E_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800607.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(34640..34810)
                     /locus_tag="ACL73E_000589"
                     /pseudo
     CDS             complement(34640..34810)
                     /locus_tag="ACL73E_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(34953..35552)
                     /locus_tag="ACL73E_000590"
     CDS             complement(34953..35552)
                     /locus_tag="ACL73E_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800608.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYAPLNDVTKYAR"
     gene            complement(35794..36678)
                     /locus_tag="ACL73E_000591"
     CDS             complement(35794..36678)
                     /locus_tag="ACL73E_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0800609.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(36682..37068)
                     /locus_tag="ACL73E_000592"
     CDS             complement(36682..37068)
                     /locus_tag="ACL73E_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGS0800610.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(37061..38404)
                     /gene="cysS"
                     /locus_tag="ACL73E_000593"
     CDS             complement(37061..38404)
                     /gene="cysS"
                     /locus_tag="ACL73E_000593"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGS0800611.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMTKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            complement(38486..39370)
                     /locus_tag="ACL73E_000594"
     CDS             complement(38486..39370)
                     /locus_tag="ACL73E_000594"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0800612.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(39382..39999)
                     /gene="cysE"
                     /locus_tag="ACL73E_000595"
     CDS             complement(39382..39999)
                     /gene="cysE"
                     /locus_tag="ACL73E_000595"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGS0800613.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(40015..42228)
                     /gene="pnp"
                     /locus_tag="ACL73E_000596"
     CDS             complement(40015..42228)
                     /gene="pnp"
                     /locus_tag="ACL73E_000596"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGS0800614.1"
                     /translation="MAKQVFQTTFVGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            complement(42913..43779)
                     /gene="metF"
                     /locus_tag="ACL73E_000597"
     CDS             complement(42913..43779)
                     /gene="metF"
                     /locus_tag="ACL73E_000597"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGS0800615.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(43843..46092)
                     /gene="metE"
                     /locus_tag="ACL73E_000598"
     CDS             complement(43843..46092)
                     /gene="metE"
                     /locus_tag="ACL73E_000598"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGS0800616.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(46353..46619)
                     /locus_tag="ACL73E_000599"
     CDS             complement(46353..46619)
                     /locus_tag="ACL73E_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0800617.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(46745..47192)
                     /locus_tag="ACL73E_000600"
                     /pseudo
     CDS             complement(46745..47192)
                     /locus_tag="ACL73E_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            47348..48349
                     /locus_tag="ACL73E_000601"
     CDS             47348..48349
                     /locus_tag="ACL73E_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS0800618.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(48417..50822)
                     /gene="pheT"
                     /locus_tag="ACL73E_000602"
     CDS             complement(48417..50822)
                     /gene="pheT"
                     /locus_tag="ACL73E_000602"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGS0800619.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDK
                     APYYAARILENVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAASSLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(50899..51408)
                     /locus_tag="ACL73E_000603"
     CDS             complement(50899..51408)
                     /locus_tag="ACL73E_000603"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0800620.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(51408..52454)
                     /gene="pheS"
                     /locus_tag="ACL73E_000604"
     CDS             complement(51408..52454)
                     /gene="pheS"
                     /locus_tag="ACL73E_000604"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGS0800621.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERKIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        14899 a        12007 c         9911 g        15943 t
ORIGIN      
        1 gtttgaagag attttcaaag agtattagaa agctcgatgg actattccag attcattcca
       61 ctagatttcg aaatcgagta ggggataatc tctagcccct ctcacaccac cgtacgtgcc
      121 gttcggcata cggcagttca actaactttt aacgcatgtc gttcaaggta ataatccaaa
      181 cacgaaacca gttcacgttt ttcaaggact ggttttgata tagcacgttt aagtaccgac
      241 ttctgagcta ctaattgata gtggtcgccc cagccagata ccttatccgc tatataggcc
      301 ttattatcac gttcctgttc gtagagccac gatttcgcta tcccttcctc tgacgattct
      361 tatttcctgc gtcagacttg ggaatcgcta ttgggttcac cggtagcagg tgcccactga
      421 ggacttacac ctcagatata cgacatgccc gtcgtacatc aaaaaaaggg ctctataata
      481 tttgtagtgg gtaacccccc tatagatatt atggagccta ttttgtgtag aaaaaaagtc
      541 ccatatgacc tataatgaaa agcgacaaaa caactcatta gaaagattca tatggaacaa
      601 ttacatttta tcacaaaatt actagacatt aaagacccta atatccagat tttagacatc
      661 atcaataagg atacacacaa ggaaatcatc gccaaactgg actacgacgc cccatcttgc
      721 cctgagtgcg gaaaccaatt gaagaaatat gactttcaaa gaccttctaa aattccttat
      781 cttgaaacga ctggtatgcc tactagaatt ctccttagaa aacgccgttt caagtgctat
      841 cactgttcaa aaatgatggt tgctgagact cccctggtaa agaaaaatca ccaaatccct
      901 cgtatcatca accaaaagat tgctcaaaag ttaattgaaa agatttctat gactgatatt
      961 gcccatcagc tttccatctc aacttcaact gttattcgta agctcaatga ttttcacttt
     1021 aaacatgatt tttcttgtct tcctgagatt atgtcttggg atgagtatgc ttttacaaag
     1081 ggaaagatga gcttcattgc gcaagatttt gataatctta atattatcac tattcttaaa
     1141 ggcagaacac aagctgtcat ccgaaatcac tttcttcgct acgatagagc tgtccgatgt
     1201 cgcgtcaaaa tcattactat ggatatgttt agcctttact atgacttggc taaacagctt
     1261 cgctttcaaa tttctaggct caggctgaaa cagtctccca gactgtttca ctcccgaatg
     1321 ctaaaatcgt tcttgaacgc tttcacattg tacaacatct tagccgtgct atgagtcgtg
     1381 tgcgtgtcca aatcatgaat cagtttcatc gaaaatccca tgaatacaag gctattaagc
     1441 gctactggaa actcattcaa caggatagcc gtaaactgag tgataagcga ttttatcgtc
     1501 ctacttttcg tatgcactta accaataaag agattttaaa caagcttttg agctattcgg
     1561 aagacttgaa acaccactat cagctctatc agctcttgct ttttcacttc cagaataagg
     1621 aaccagagaa atttttcgga cttattgagg acaatcttaa gcaggctcat cctatttttc
     1681 agactgtctt taaaaccttc ctcaaagata aagaaaagat tgtcaacgcc cttcaactac
     1741 actattctaa tgccaaactg gaagcgacca ataatctcat caaacttatc aagcgcaatg
     1801 cctttggttt tcgaaacttt gaaaacttca aaaaacggat ttttatcgct ctgaatatca
     1861 aaaaagaaag gacaaaattt gtcctttctc gagcttagct ttttttcaac ccactacagt
     1921 tgacaaagag ccaaaaaaag ttgagacata gcgtcttcaa cttttttaca ttactttaac
     1981 tactgattaa agtgagttta catcaacttt gataccaaca ccttgagtag ttgtgatagt
     2041 caagtttgtt acgtaagttc ctttagctgt agctggtttt gctttttgga ttgtttcgtt
     2101 gaaagcttta aagttttcaa ccaatttttc agcttcaaat gatactttac cgatgattgc
     2161 ttgaacgtta cctgcacggt cagcacggta agtgatttta ccacctttag actcttcaac
     2221 tgctttagca acatccattg ttacagtacc agttttaggg tttggcatca agttacgtgg
     2281 tccaaggaca cgtccaagac gtccaacaag agccatcata tcaggtgtag cgataactac
     2341 gtcgaagtcc aaccaaccgt cgttgatttt agcaacaagg tcatcttcac caacaaagtc
     2401 tgcaccagca gcttttgctt cttcagcttt tgcaccacgt gcgaaaacaa gaacacgtga
     2461 agttttacca gtaccgtttg gcaataccat tgctccacgg atttgttggt cagctttttt
     2521 aacgtcgatg ttcaagttgt aagcaacttc tacagttgcg tcaaattttg caaagttagt
     2581 ttcttttgca agtgctacag cttcttctac gctgtatgct tttgtgctgt cgattttctc
     2641 aagagcagca cgaagttgtt tgcttttttt agccattttc tattctcctt gtaagtggtt
     2701 caatcgattt tcatctccca cgtcacttct cgaaatgatg aagtcttgcg ggttttcagt
     2761 ctactatttt tctcttccta cggccttaag ctcccttgct gtacccaagt acaagcctca
     2821 gtcacttgcc tagtatgaaa agcaactaat agactgctgt gagattttct actgtgttat
     2881 tgattagtca acaacagtga atcccataga acgagcagta ccttcgatca tacgcattgc
     2941 agactctacg tttgctgcgt tcaaatctgg catcttagtt tctgcaattt cttgtacttg
     3001 tgcacgagta actgtagcaa ctttagtttt attaggtgta cctgatcctt tttcaacacc
     3061 tgcagctttt ttcaaaagaa cagcagctgg tggtgttttc gtaacgaaag taaatgattt
     3121 atcttcgtaa actgagataa caactggaat gatcatacca gcttggtcag ctgtacgagc
     3181 gttgaactct tttgtgaatc ccatgatgtt gataccagct tgaccaagag caggtccaac
     3241 cggtggagct ggtgtagctt taccagcagg gatttgcaat tttacaagtt tttcgacttt
     3301 tttagccatt tttaaatcct cctttgtggt tttggcggta attagagatt tttacctccc
     3361 acaagtatgt ttttcgcata cccattcatt atacactatt tatctggaat tgcaagagaa
     3421 aagtttattt tttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct
     3481 gctcaaagta cagctttgag gttgcagata aaactgacga agtcagctca aaacactgtt
     3541 ttgaggttgt gaatagaacc gacgcagtca gtaggtaaga cgacgctgac gtggtttgaa
     3601 gagattttcg aagagtatta atcgacgtag tctccgcctt caaagccata gtattcttcc
     3661 aaactgagac cacttgcagc aatttcttta gcttcttttc ctacataacg caggtgccat
     3721 tcctcagcca tatagcctgt ttccttttcc ttgcctttga gataacggac aacaaagcca
     3781 taatcagctg catgatccaa gagccattgg gctgcttttt cttctgtcac caaatcacca
     3841 tcagtcccaa tcacatcaaa ggccaagcct gtctggtgtt cgctatagcc aggacgggca
     3901 gagtaacggt cagctgctgc ctttccatct tggttgacat aatcttgata gagcttggtc
     3961 tgagtttcat aacttctaaa accactgtaa tgatcactaa tagggaaacc tgcctcttgc
     4021 atcgctttga tgagtttgac caactcagcc ttggctgttg gattttcccc gggattatag
     4081 tctttcgaca aaggataatg tttattggct acgatgattt cgtcgtattt tccttggatg
     4141 ctgtagtaat cacctttatt gaccacttct gcttttttct gggcagcccc ttgagactta
     4201 ctgccgactg tcccatcagc tttggctgtc tgttctgtct tagctgtgcc atcttcattt
     4261 tttgcttttt cttgtgaaca agctgctagg gttactgcca gcaaaccaga taaaacgatg
     4321 tatctttttt tcattttttc ttcctctatt cttcctctct tagaccgtgt acttctctaa
     4381 ttcatcggat aaggctttaa tcatttgttc caactcatgg gatttcactt ggcaatcttc
     4441 tgccgccatt tcttcccagg gcacccacca gactggacca cggccattca atccatgacc
     4501 cctcatatca cctgaccgtc ttggaaagag atgccagtga gcgtgggcat ctccatttcc
     4561 tagaagttca atgttcatct tttcagcttt aaacgttttg gcaacagctt cttggaccaa
     4621 actcatttcc tctagaaaac gaagttttac agaagtctcc atatgatgga gttctgtgac
     4681 atgctctttt gctagaaata aggtatagcc cttaaagtat tggtggtctc caataacaac
     4741 atagcctgtt tctagttctt ttacaaagta gggattttcc cctgccttga tccattcaat
     4801 tctttgacaa atcaagcaca tattagtcta ccaatgcact cttaagataa gcatcgacca
     4861 tacgctcagt cgccactact gaatcaatgt gtgttcgttc gtaagagtga cttgactcaa
     4921 taccagctcc aaggagagca tgctttactt ctgctcctgc agacatagct gccgaagcat
     4981 ccgaaccgta aaatggataa atgtcgagct taaatggaat atcttgctcc ttcgccaaaa
     5041 ctaccaagtg ttgacggaag tcatagtgat agggacctga agcgtccttg acacagatag
     5101 acactgtata ctcatccgtc tgctggtcat ctcccatagc tcccatatct acagccagat
     5161 attctactac ctgacttgga atattggagt ttgcaccgtg gcccacctct tcgaagactg
     5221 aaaaagcaaa atgagttgtt actggcaatt caatcccctc ttccttataa acacgaagaa
     5281 gattgagcaa aattgctgcg ctgaccttgt catccaagtg gcgagacttg ataaaaccag
     5341 tctctgtcac gacagttcgt ggatcgaagc tgataaaatc accgacctca atcccaagag
     5401 cacgagtttc tttttcattg cttactttta catccaaacg cacttccata ttgtcctgcg
     5461 tgcgttctgc agttcctgca tccttgtaga catggcaaga agtttggtgg atgaggatgg
     5521 ttcctgatac cttttgacct gtgctagcca catgaacggt acagttttca ccttcaatca
     5581 tgttccaagg aaaaccaccg atacggtcca atttaagacg accatctggt ttgacagcac
     5641 gaacaatagc acccagcgtg tccacatggg cagtcacata gcgatgttgc tcatcatttt
     5701 gacctttgat ggtcacattg acaccaccct tggctgtgcg aactggctgg taaccaaaac
     5761 cttctagagt cttgactaaa taattcgaaa tttcacgagt gaagcccgtt ggcgatgcga
     5821 tggctgtcag ttctttgata tattctactg tttgattcat ttcttcacct ctttcgctac
     5881 ctattataac acatttatca tcggataaaa aaagaaaatc actcctgtag acttggctac
     5941 aaaagtgatt taagtgatta ttccatttca aaaacatcgc tttcttgctt gtttggtaga
     6001 accaatgaga gcaagattcc aacaatggct ggcaccaacc atgggagaga tgccttggca
     6061 aaaggaagaa cgctaacaag atttgcaaga aactcaacct taaacgagct tcctagtacg
     6121 cttgcaatgg caataactgt aaccacagca attgtcaact gcatacctgg ttttgaaagg
     6181 gcaacaaatt tgttgacaat gacaatcata acgatagcaa tcgtgattgg gtacaagata
     6241 accagtactg gaattgagta cttgataatc gcatcaagac ccaaattggc aatagcaaat
     6301 ccaatcaagg taaaggctgt cgcataaacc ttgtagctga tttgtgggaa gcgctcatta
     6361 aagaactcag ctgttgacac aatcaaacca acagtcgttg tgaagcaggt tacggtaacc
     6421 atagctgcaa ggaagagttg agctgttgag ccaaagattt cttgagtggc ttgtgacaag
     6481 atgtaaacac ctggtgttcc acccttcatc gcttcagctg gtactgggaa atgatttcca
     6541 agaaaaccta aaccgatgta aagagcgctg aaggcaaggg caacaacgat accaacaacc
     6601 caaatagttg aaatgtattc tttcttactt gaaaatccaa gttgtttcaa ggtttgaact
     6661 gcgattacgc taaaggccac tgaggcaagg gcgtccaagg tattgtaacc ttctaggaaa
     6721 cctgtaccaa aggcagaagc ttgataagca gctgaagcag cttgaggact tgttccacca
     6781 tatttgatag ctcccagaac gaccaagata acaatcaaaa ttgcaaagac tggcgttaaa
     6841 atacgtccaa tgcggtctaa gatttttgat ggattaagcg aaatcaaata ggctgccgca
     6901 aaatacagaa ccgtaaatac aatcaagcca agtcctttat ttgcatccga caaaaggggg
     6961 ctaatcccta cttcgtaagc tgttgtagca gtacgtgggg tagcaaagaa tggaccgatt
     7021 gacaagtaaa gaactgagag gtaaagagtc gcaaaccaag gcgctatctt cgttgaaatc
     7081 tcgtagatat atcctttagg atttagcgtt ccaataataa gggtcaagac ggcgatacca
     7141 acgcctgaaa agacaaaacc tgcgatggca ggaagaaaat gttctccaga tagagcacct
     7201 agagaaggcg gaaaaatcaa gttccccgca ccaaaaaata ttccaaacag gagcaaacct
     7261 gttagggtac cttttttagc cataaaaatc tccttcatat ttataaaata ctgacctagt
     7321 ataccacgat taggagtctg aaaaaagcat cacgaggcaa atattaaatg ttttcaattt
     7381 tcttaaaaat aagaattatc taaaaataaa actctcctac ccagtccaca ccaagtagga
     7441 gaaatgcaaa attttaaagt tcttcaaagg ctaacatgcc accctggaca ttgataacgt
     7501 tataaccttg ttctaacagg aattggcaag cacgcgccga tctcattcca gatttgcaaa
     7561 taatataatg caagcgatct ttgtccaatt aatcataact atcagccaat tgactaagcg
     7621 gtaggttgtg ggtaccttct aaatgaagag ctgcaaactc atccacttct ctcacatcca
     7681 ctagagaaag ctggtcgttt tggtaaagct gataaaatgc gtcaaaggct atttctttca
     7741 ttctttttct tctaatactc tccgaaaatc tcttcaaacc acgtcagcgt cgccttaccg
     7801 tgcgtatgtt accgacttcg tcagttttat ctgcaacctc aaagctgtac tttgagcagc
     7861 ctacgactag cttcctagtt tgctctttga ttttcattga ctataaaatg gttttaattc
     7921 tttttttcaa atctggcact acttctgcct caaaccaagg atttttggcc atccagattt
     7981 gatttcgtgg tgatgggtga actagcagaa aataggctgg cagatagtct ttatagtgtt
     8041 tcaccctctc cgttaccttc ccactgattt tctcctgtaa atagtaggct tgggcatatt
     8101 gcccaatcaa gagggttaac tgaatatcag gcaattcctg taagagctgc ggatgccatt
     8161 tttctgcaaa acctgtacga ggcggaagat cacccgactt gccatgtcct ggaaagtaga
     8221 aatccatagg caaaacagca aaataacctg aattgtaaaa ggtatcttca tctacaccta
     8281 gccagtcccg caagcggtca ccacttttat ctttccagta aaggcctgct tcttgagttt
     8341 taagtcccgg agcctgaccg atgatattga tgcgagcagt ttttggcgct gcaaagagag
     8401 gctcaatgcc acgctctgta tagctggcat tctgcgaatc cgccatgata gcctgtttga
     8461 ttctttcgat ttgagacatc tactttccct ccaaaaagaa gtccaagcat aagatctcag
     8521 acttctatcg ttttatttga tcaattcgta aatagcttcg gcataaattg ctgctgctcg
     8581 gaagagatcg tccaaggcaa taaattcatt ggcttggtgc atagtatcaa ttgagtctgg
     8641 gaacatagca ccataggcaa ctccgcgctc taacaagcga ccaaaggttc caccaccgat
     8701 gacttgctca tgaccttgta ggccagtttg tttttcatag acattcaaca aggtttgcac
     8761 aagtggatct tccattggca catagtgagg ggtatgacca tgttctgata gactgacaga
     8821 agcaactggc aagttttcta ggattgactt gatttgttct ggacttgttc cttttggata
     8881 gcggatgtta agggcaatgg tattatcagc acttgtttca tcgaagcgga agacgccggc
     8941 attcatagaa agagccccca tcttttcatc cacatgagca atcttgagat tttcaccctc
     9001 atgatcgttc aagagaattt tacctgcgat gtcaaggtag tctttggctg gaccagcaaa
     9061 gccaaactgg ctgaggaaga gggcaaggta agttgcgcca ttgacacctg aagcaggcat
     9121 agcaccgtgg gctgatttac caatgatcgt caccttgtat ttgccagctt cttcttggag
     9181 ttctcctcta agtttgtgtt ctgcaacaaa ggcatctagt ttagcttgca agtcagccaa
     9241 atcacctgaa acgactgctg ttgctgattc tggtaccata ttttcacgta aaccacctgt
     9301 aaagctgtga agacggacag cacctgtatt ttctcctgca aagtggaggt attccgtgat
     9361 atttcctttt tcaccattga tgattggaaa ttcagcatct ggtgagaaac cgaaatctgg
     9421 tttggcaagt cctacgtgct caaagtagta gtccatgtct gcccagcctg attcttcgtc
     9481 tgttccaacg atgaagcgaa ctttcttaga agttggaagg cctaattctt tgatgatttt
     9541 caaaccatag tagcaagctg ttgtaggtcc cttgtcatct gaagcaccac gcgcataaag
     9601 gcgaccatct ttgatagttg gtgtgtaagg atctgtatcc caaccgctac cagctggaac
     9661 cacatccata tgggcaaaga ttccgagaac ttcttctcca tcaccaaact caaaatgtcc
     9721 tgcatagtta tcaacatttt tagttggata accatcacgg tctgcgattt caaggaattt
     9781 ttccaaggct tttactggac caggtccaaa tggatgttgg gcatcagcct tgctatcatc
     9841 acgttctgag ttgatttcca aaaggctaaa caagtcagcc aagaggtctt ctttgcgttt
     9901 ttctacttct gctgtaaaat caattgctat cattttttct tcttcctatc ttttttcgat
     9961 gatttcatct actggcaagc ggtagcttgg ttccaatttg tcgtctgtgt aacccactgt
    10021 gatcaagagt tctgggcgga aacggtctgc gatttccaaa acttcattaa cttttgattt
    10081 gtcaaaacca aggataatat tggaaccaat tccttggtct gtaagagcga gaaccaagtt
    10141 catagcaacc aaacctgcat tgagtgctag gtagtcgctg acttgttgtt cattgtagcg
    10201 tgcaaattca gctggcaaat ttttcatgaa gtattgaagt tgttcttctg agaaattgtt
    10261 agcaccacca actcgggcaa tcttacgagc gcgtttggca aggtctgtat ctgtaaatag
    10321 ggcaatggtt acaggtgctg atgatacctg ttcaaaattg gaaccataag ctaactttgc
    10381 cagttcagca tttttctcac gtaccaccac aaatttccaa ggctggctgt tgtgggcgct
    10441 tggcgccaag gttgcaattt cgatagccgt acgcacatct ttgggatcaa caggcttatc
    10501 agtaaaatgc ttggtcgcat gacgtttttt atttaattca agaaatttca taatcgattt
    10561 ccttttctaa ttctactgct tccattctac cataatttga aagagcttgc agggattttt
    10621 catgattaag tttttctatc acagacataa aagatatata ttggtttatc aggaaagttt
    10681 ctgataaact agcaagtact ttacatttga atggagacag tatgaaaaaa tttagcctat
    10741 tactagctat cctaccattt ttggttgcct gtgggaatca agctacaccc aaagagacta
    10801 gcgctcaaaa gacaatcgtc cttgctacag ctggcgacgt gccaccattt gactacgaag
    10861 acaagggcaa tctgacaggc ttcgatatcg aagttttaaa ggcagtagat gaaaaactca
    10921 gcgactacga gattcaattc caaagaaccg cctgggagag catcttccca ggacttgatt
    10981 ctggtcacta tcaggctgcg gccaataact tgagttacac aaaagagcgt gctgaaaaat
    11041 acctttactc gcttccaatt tccaacaatc ccctcgtcct tgtcagcaac aagaaaaatc
    11101 ctttgacttc tcttgaccag atcgctggta aaacaacaca agaggatacc ggaacttcta
    11161 acgctcaatt catcaataac tggaatcaga aacacactga taatcccgct acaattaatt
    11221 tttctggtga ggatattggt aaacgaatcc tagaccttgc taacggagag tttgatttcc
    11281 tagtttttga caaggtatcc gttcaaaaga ttatcaagga ccgtggttta gacctctcag
    11341 tcgttgattt accttctgca gatagcccca gcaattatat cattttctca agcgaccaaa
    11401 aagagtttaa agagcaattt gataaagcgc tcaaagaact ctatcaagac ggaacccttg
    11461 aaaaactcag caatacctat ctaggtggtt cttacctccc agatcaatct cagttacaat
    11521 aacactcttc gaaaatctct tcaaaccacg tcagctttat ctgcaacctc aaagctgtgc
    11581 tttgagcaac ctacggctag cttcctagtt tgctctttga ttttcattga gtataagata
    11641 tactaaaagc gatgggatca gccaatcgct tttttagttt gcattggtta ttttaggaaa
    11701 ctcttacaaa aaatcaaaaa aattcttcac atcctctaca tacccatgct tttctattaa
    11761 gcttgctaat agttccagat tgtgcccctg atagttatct tcacgacgta gttcttcata
    11821 catttcgata aagggaagcc ccttggattt ggcaaattct aactcagcct cgtaatcata
    11881 agcgacttta cgaaatagga tatttaccaa ttccccatct tcaacctcta tcacgttaaa
    11941 atagggcatg ccaatcgacc ctggattgat gatttgttgc ccttgactac cataacgaag
    12001 caactgcttg tgaacatgac cataaactgc cacgtccgtt tccgcatcta gcagttggtc
    12061 aaatttctct gtatcattct caactagcaa gtcaccacca tagtttttgt caggtaaatt
    12121 atgagagata gaaaagcgca atccgtcaat ttctttcttt tccagcaaag gcaagcttcg
    12181 tagccagaca atcgttgcag gatccattcg ctccatcaaa tactgtgtca tacgcaagag
    12241 ctgaacttcc tgtgggtctt ctaagccata ttgcccatct aaagcctcaa ggacacgatc
    12301 atcccaattg cctcgaacac ttgctgtgat aggaaggtcc tttagcaggg cgactaagtc
    12361 atttgcgcct ggaccaggaa gaaaaatatc tcccagaagc cagtattcac tgactccttg
    12421 atttttagca tctgcaatca ctgcttctag cgccgtcgca ttgccatgaa tatctgataa
    12481 aattgcgatt ttatggttca ttgtggtttc cttctgtttg gtaatctact ctttcttccg
    12541 ccacttgaag caagatttct gtttcctgcg ggttcaactt tctttgcaca gcctctgcta
    12601 ctgctcttgg tactccaact tcgacaatct catccacacc ggcttccttg attttggtca
    12661 gagacttgaa gtgcctcatg agattttgct tgcgtttagg tcccagacca tcaatcccat
    12721 ccaattgaga tgagaaagaa tttttggagc gcagttggcg gtggaaggta atggcaaagc
    12781 ggtgcacctc atcttggatg cgttggagga ggaaaaattc ctgagaattg cgagacaagt
    12841 ccaccacctc aagcggatct ccaaagagca gttcatgggt ttggtgctta tcattctttt
    12901 gcagacctgc aattggaata tccaagccca gttcttcttg gatgacttgc ttagcaatat
    12961 tgacttgacc ttgcccccca tcaatcacaa tcaaatctgg aggagtcaaa gcctcacgct
    13021 gtactcgacc atagcgtctg cgaatgactt ctctcatact agcatagtcg tccggcccaa
    13081 caacggtttt tatcttgtac ttacggtaat cttttttact tggcctgccg ttaacaaaga
    13141 ccaccatggc tgaaacagga ctggtcccca tgatgttgga gttatcgaag gactcgatgc
    13201 gaactggagt cggaatttgg agcaaacgtc ctagattttc aatagctcct tgggtctttt
    13261 cgactgattt ttctagcagg ttaaatttct gctccagact aacacgtgca ttttttatgg
    13321 ctagattgac cagctgtttt ttctctccac gttggggttt gagaatcttg gtatccacca
    13381 aagccttgac agcttcttcg tcaatatcct gcggaatcag tacctcattg ggaactaggt
    13441 gagatttttc ttgatagaat tgtcccacat aggtcaagaa atcctcatct ggatcattga
    13501 agtaggggaa gagattgaca tcgcgctcga tgagcttgcc ctgacgaaca aagaaaacct
    13561 gcacacacat ccagccctta tccacatagt agccaaagac atcgcgattt tggagatcct
    13621 tagccatgac ccgttgcttg gttcgaagtg ttccaatggc ctgaatcagg tcacggtatt
    13681 ccgctgcccg ttcaaactcc atactttgtg ctgttactgc cattttactc ttgagatcat
    13741 cgatgatttt gtcatcctga cctttcagaa aatcagacac ctcctgggcc atggacttga
    13801 aataggcctc gtcattctta cagatggtgt gggccataca ttggccgata tggtagtaaa
    13861 aacagacctt agagggcggg ttggtacatt ttcgaaaagg gaaaatccta tctagaagtc
    13921 gcttgatttc attggctgcc cccacatctg gataagggcc aaaataaaga ccaccgtcct
    13981 ttttgacctg acgagtaatg ataagccgtg gatagtgctc attggtgatt ttgataaaag
    14041 gataagactt gtcatccttg agcatgatat tgtacttggg cttattttcc ttgatcaggt
    14101 tgatttccag cagaagcgcc tcaatattag actccgtaac aataaattca aaatccacaa
    14161 tttcagacac caaggcctct gttttggtat catgacttcc acggaaataa gacctcacgc
    14221 gattacgcag atttttagcc tttcctacat agataatggt gccgttttta tccttgtaaa
    14281 tgtagcaacc agggctggtc ggcaagagct ctagttttgg tttaatcaag ttgttcatag
    14341 ttccattata gcaaaaaagt agggaaagat agtaccctac tcattagtct catatatttt
    14401 tcggaggttt gcaacatcct cttcctggat accataaaag gaacctgctg gttgcatgac
    14461 agacttctca tctgtatggt ccaagccaat cgcatgacct aactcatgtt ctgccgtatg
    14521 gacaaggcgt tcataggaat agccatagta tggattggac aaataataat gattcaaccg
    14581 caccgttacg gacaagaatt gccctgttaa gagattagtt tgactttccg cctctcctgc
    14641 cacaggagtg cctccgtcgt tcatctccgt agccgtaata tccgccttac tagactcagt
    14701 cacgagttca aagttaaaag caccagtttg attccagttc tggattgctt ctaaataagc
    14761 ctcttgaaag cgtgaatcca tctgcggatc caggtaaata cgagcagagg cctgtgccca
    14821 ccttccttca gaatgctggt gactatctgt ctggcttaac ttaggcagtt gccctgtttt
    14881 ctcccattgg tcaatacttt gttgaccaat ttttactgac cgttctgctt gctttagcgc
    14941 tccttgaaaa tccccgttca gataccagag aagtccgaaa gcaagcacac ataagagcac
    15001 aactatccaa accagacgcc aaaacaaacg ccacacaaaa gaaaagaaag cccctatcaa
    15061 acgaaaaagc cagcgcatgt ctctccacct ttctagcaaa taagaattat tttactaaaa
    15121 gaagctaaaa gaaatctaaa tactgacttt ttcatcttaa cgtcctacta tttttttgag
    15181 taactggata gctttgtatt ttaaaggcga tggatggtaa cggaaagtac ccgctttgcg
    15241 tacaatatag ccattaaaat tctgtttaaa acgcaaaaca ccatcacttc catcaaaaat
    15301 cccttgaatg cctaggaaat tgtatttagg tattccacgt tttatgcttt ccaacataac
    15361 atatttttga agcagtgcag gggcatagaa cttattaaac tcagtgtagg aaccactaaa
    15421 gagataagtc gtttcctgag gcatataaac aaataaactc ccagctaaaa caatatcttc
    15481 ttctccatat ttttcaatca agtctcgcgc ttctgctttt cgaacttcaa acgtttcaaa
    15541 ttgactagaa tattctctca gttgattttg ttttttctca gaatgaggat ttttactcaa
    15601 atcaagtcgc aacttgtcca agttttcttc tagtttattt tgttcacctt gcaatttgct
    15661 catatagtcc gaaaaattta agcttgctat gagaaactcc gcttgttctc caaaagtatc
    15721 ataaaaatgc tcataatatt ctaaactttt atcactatat tctctacgtt cagaggtttc
    15781 ttttgttata ttcttaaaaa tcgatagttc ttcacgtttt aactttttca accgaatgcc
    15841 aaaggtttca gcctttttca ccaagggttt accctttttg ctaaaacttt taagcaaact
    15901 cttttcagtt aattcagtta aatctttata gtataaccaa tctggttctc cacctgggta
    15961 acctgttgtt aagccatcaa attgataacc taaatcagtc aaatcttgaa taatactttt
    16021 tttctcagca tctattggat taccttggct atcaaaagtt tgataagttt catagggttt
    16081 tacaagcaac tctaatacac cattttgctt ggcatattct tttaactctg cataaaaaac
    16141 tggaagagca tcttgttggg tataaatcgg ccccgaattg agttccatat gcagaccacc
    16201 cagcatgggc aagctataaa ccagagctgc aacttgaatt tctccttctt gtttcaaagc
    16261 aagataaaca attcgagccc ctcttttttc tagcaaatcc cccatctgga cagattgcat
    16321 aaaggaacga gaagaaacct gatcagaata agtctgaaac tcttctttcg tgagtgttgt
    16381 tagtgccata tacttacttt ctatgttttt ttcttaatgt tttacggaaa tcaagagcaa
    16441 gtcttaacag aggatagaga ggatgagtgg gcattgtaaa ttcacccaag tattcttcaa
    16501 tcgttggatt aaatttttcc ttaaaatgat aaagtccacc attgagagag ttttcaacac
    16561 cacctaaatt ttgccagatc atacctcgct caaaggcata gcgagccgtt tcataccatg
    16621 ttaaaattgg tgcattgtaa cgtttaaaat catcatccat accagcatat atattgacag
    16681 aggtagtacc aaattccaaa ctcaaagtag ccgctaaagg aactctcgct tgacctacat
    16741 ctatatattc ctgcaagaag gtcaattcct ctaacaaacg ttctttttcc ttcttctgcg
    16801 cttctacttt tgaagttcga gtcgactcag taaacgtctc ttccaaggct ctatttttcg
    16861 ctaactgttc ttctaattct tgcgaacgtt tagaaacatc caaggtggcc aaggtgatat
    16921 aggccttgtc cttaaaatta tctaacaatt ttttataata ggcttcattc ctcaaatgaa
    16981 tctcttttcg cttctcagtt tttttcatca actccgaaaa tgaatctaat agttccagtc
    17041 caccatattg aatctcaagc cctttgtttc gtgctgttcg aatagtctgt tttgttgact
    17101 tggaaagttt atcttcttca aaattttcct tgtatatttt cgcctgaata cgaggttgaa
    17161 tggtgtctcc catttcctcc gtttttcctg accaccttac tcccatttgt tgcaaactat
    17221 caataatagc cagattttca ggaaattctg tcttttcctg attgattaaa ctttgagata
    17281 ggcaaatact tgggtcaaaa gtcacaaaaa ccgctctctt actgcgagca taggacttaa
    17341 tagactgaat ggcaaaattc aagagttctt tatccccata atccaatata ggtcctcttg
    17401 ggatgtaaaa cattttatag cctagcggaa gagttctaat caaaatacta gctgtcgcca
    17461 gtaatttttc ttccctgtaa acaccaaact tctcatgttg ccaattagac ttaacttcct
    17521 cccaagcact actttgtaat acattggcta attcatgttc tttgacaaac tgatcatatt
    17581 ctaatgtggg aatgccaatt tgataacggt acatttccta ctctctttcc tccagtattt
    17641 tattactatt ctactacttt cgtttgaaaa gtctagtgaa aacatatttt attttagttc
    17701 tactccccct atgctgaagt tcaaactaag tcagtctctc ttctaatttg aaatcaattg
    17761 gtagggttgt taaaaaaact tccaattgtt tttcccagta gtaccactcg tgagttccag
    17821 cgctatggct ataggtcaca tcaaaaccta gttttttgag atttttcact gcgagattat
    17881 tggcttcgta caagaaatcc tgttcgccac accacgccca aagtttggtc tttttatccg
    17941 attttttagc cagactttca agagaatagg gactagttgt ccagtctcta atctctccaa
    18001 aaacacctct ccagtaggct ggacttccca gattttgact ttcaggagaa aagttttgaa
    18061 agctgagggc acctgaaaaa ctagctgcat gagaaaaacg atttgtcgca agagccagtt
    18121 tgaaacagcc gtagcctccc atagaaagac cagctataaa ggtcttttca cgcttgctag
    18181 tcatattagg gaagaagcgt ttcagaacct gtggcaattc ctctgctaga gccgtgtagt
    18241 agtcaaaacc atactgggta tcggtgtacc aaccattgct ggtattgggc ataacaacga
    18301 tgagattagt tcctcgaagc aagcgttcta cattggtccg cttaagccaa ctattatgat
    18361 ttccagacat cccgtgcaaa aggtacaaga cgggaatatc ttcacactct ggttcttcca
    18421 ctcgattggc atcagggtag aggacattca tcccccactc catatccaat acttgtgagt
    18481 aatactcgat tttcattact gccatgattt tctccttcta tttttctata agaaaaagcc
    18541 gaaactcgac tttctctctg tttatttcaa cgattatttt gcttccatga ctactggtaa
    18601 aatagctgga cgacgcttgg tttggtcaaa gagatacttg gtcaaattat ctcgaacctt
    18661 ccctttaaga tctgcccagt caaagtcatc tccttgaaga taatcttcta ccgtttggtt
    18721 aatcaattct gaactttcac ggagaatatc gcgactcttc ttgagataaa caaatccacg
    18781 cgtgtgaaca cgagctctag ccacaatttt cttctcacga cggttgactg taatagccac
    18841 gatgaaaatt ccatcctctg acaagacctt acggtcacga agaacaacat ttccaacatc
    18901 accaatggca ttcccatcaa ttaagatatc tcctgctgaa accgatccag ctggaacaaa
    18961 gtctccattc tcgtaagcca tggtcgtccc ctttttagga atgaagatgc gttctggcaa
    19021 catcccaact gccatggcag ccttagcgtg agcatccaac tcacgatact ccccttggac
    19081 agggaagagg tacttaggtt gcaaaagatt gatcatcagc tgcaaatcac gcacatttcc
    19141 gtgccctgat acatgtaaac tttgggtaat caatttgaca accccacctg cctgataaat
    19201 catattttct acacgcgcaa caaaggcttc tttagcaata gacggagccg tagcaatata
    19261 gaccaggtcc ccatccttga tttctacata acgatggcga ccaatcgaca tcttacgaag
    19321 tccattgata ggttcaccca tacgacctgt ctcaagaata atcaactcat ggtcttcaaa
    19381 gcgagacata tctttaggct taatcaagag aatttcgttg gctaaagaca acttcttaag
    19441 acgaatcgct gtgcggacga tattttcaat atcaaatcct gtcaagacga tacgtcgacc
    19501 tgttttatcc gcagcgtcaa aaatctgctg aatacgagaa agattactgg aaacagctgc
    19561 aacgatgata cgaccttccc agtcagcaat agtttgggta atttcatccc taacttcact
    19621 ttcactagcc acctgaatat tgctgtctgc attggccgaa tcactgagga gagccaggac
    19681 gccgtcacga ccaatctctg ccaaacgagc aaaatcagtt gcataagatt cactagccgt
    19741 ttggtcaaat ttgaagtcac ctgtataaac gatgcttcct tccgatgtct tcaagacaat
    19801 tcccagactc tctggaacgg agtaagtcgt agggaagaag gaaaccactg tcccaccaaa
    19861 atcaatctcc gtattctcat caatgacatg gaaatcatta aatttcttaa cggcatcatt
    19921 tcctttgaca aagagctttg ccaactcaat ggtcaactca gacccaaata caggaacttt
    19981 agcctctgcc aagagataag gtagagcacc aatcgcatcc gcatgcccgt gggtcaagaa
    20041 aaccccagca atacggtcgc tattttcaaa aaggtaatcc atgtttggaa tcaccacatc
    20101 gacccctaat tgttcatttt caggatattt taaccctaca ttcaaaacaa aaatggactc
    20161 tccaatttca gcaatgtaca tattttttcc attctcacgc acaccaccaa gtgttgttaa
    20221 actgatatta ctcatttttc ctccaaaatc ttagtttatc ttgattatag ggcaactcta
    20281 ccctcttatt ctaaaagttc taatactttc agccgaatct tttcctacca ttataccatt
    20341 tttttgatga ttttcaaaat gaaggtctgt tttcaaaaaa gagttgattt cccaactctt
    20401 tcctaacttc tactcttttt ccatcaaaaa atcataaatt tcttgcacca tacccagcgc
    20461 catcatttct tggtctttaa cggtttgttt gagattttgg taaatttgac tttctcctat
    20521 ctcccgcttt ggcgcctctt tattgactgt catcacacca tcttttatcg tcacaaagcc
    20581 tagttcttca aatacttgaa tcatcttgac cagcaagatt tgttgaatat taagatatgc
    20641 agccaaatct ttcagcttgt agcgaatatc aaactctggg aactggtaaa tagtcttgta
    20701 caatttggca aactgatctc tagtcccata acctgtcaga taataggcct tgtcaatatc
    20761 atttttgaaa tagacagcag agaaatgctg ttcctgaaaa atggtcttca gctgagtaat
    20821 atcctctgga atgtttttta cgacaatagc ttcactagcc gcaagatttg gcagttctcc
    20881 aggaaaatcc aagactggaa caccttctgg caagactgca ttttttccac gaatgttaaa
    20941 aagttgaaca ccttccactc gcgcatccac catcatcaac tggagggcag tttggccatt
    21001 ccattggttg acagacaatt taaccgctaa ctctagattc ttggtttgag aaaactctgt
    21061 cgcccatctg ccttgaccaa aggctaccac ttcaaaactc gcctcaccct tggaaatttt
    21121 cagctttaga tgggcattac ctgcccccat agtacgagca ctttcgacct gaaaattctt
    21181 gatataaaaa ataggtttct gattatccat tccaaaagga gctaaacgtt caaaactttt
    21241 gaccgtttcc aagctaagtg cctccaaatc caactcttca tctaggttta acttattctt
    21301 gccaccagca tctgcacctt tttcacgaac ataatcttcc aaaacctgag ataaatctga
    21361 gagttgctca acttccagcg tcatacccgc tgcacctgca tgacctccaa aggcgataaa
    21421 gaggtctcga tggggatcca gagcttcaaa aatatcgacc gcttccacac tacgagcact
    21481 gcccttggca cgaccgtctt ctatattaag aacaatgact gtctgtccca attcttccaa
    21541 taaacgacca gccacgattc ctagaacccc aggattccag ccttccttgg ccaagacctg
    21601 aaccttcttc tcaggatcca ccatggtctt ggcttcttca tagatagact gaacgatttc
    21661 cttgcgctct tcgtttttct ggtgaatcat aaaggcaatc tcatgcgctt cctcatcatc
    21721 aaatccagtc aacaaatcaa tggcaggatt gggatcatcc aagcgaccca aggcattcaa
    21781 acgaggagca atctggaaac caaccgtttc ttctgttact tcgttggcag caatcccagc
    21841 catgtccagc atttcttgca gaccaatgcg ctgggtatga cccaacattt ccagaccata
    21901 ttgaactaag atacgatttt catccgtcag actcaccata tctgcaatag ttccaatagc
    21961 gaccaaatca agcaattcca cttgcacttc ttctaacagg gcacaagcca acttgaaagc
    22021 aactccacaa ccagccaaat atttaaaagg ataatccgca tctggatgtt caggatggac
    22081 aatagcataa gcatctggca gggtttcagg catggaatga tggtctgtca caatgacatc
    22141 tactcccata gactgagcca atgcaatagc ctcatgacca gcaaccccat tgtccaccgt
    22201 cacaatcaag gaaattcctt cttgctcgat aaagtattta taaacactag cattagggcc
    22261 atagccatcg gtaaaacgat ttggcaggta aactcggcac tcagcaccaa gttgttccaa
    22321 actttccttc acaatagaag ccgaagtcat gccatccgca tcatagtctc cataaacgag
    22381 aatattttcc ccttcttcaa tagcctgacg aatccgctcc actgccttgt ccatatcatg
    22441 gagcagataa gcatcatgta agtcctccaa ggaaggttct aaaaacttct tcagactttc
    22501 ttggtcctga atccctctct caaacaataa ccgagccacc tcaggaccca gtccagcctt
    22561 cttggctatc tttgtaaaat ccgcatcttc tacctgcagg gcaaactgcc attcataagt
    22621 aggtgttatc aaaaagacat ccactctttc taagaattct attgcttcat tataacatga
    22681 tttagacgtt ttctctatcc agattgcttt tttataacat tttatagtat attgaaacta
    22741 gaatagtaca cctctacttc taaaatattg ttagaaatcg atttgactgt cccgatcgat
    22801 ttgtcctgtt cttatttcac tatagtgaat tttttcagat atggtttgac aagaacattc
    22861 ttttattgta gaatcgtgtt ataaaatcta acacaaagga gatctctcat ggctttagta
    22921 gaatttaaaa acgtcgaaaa atattacgga gactaccacg cactccgcaa catcaatctc
    22981 cgttttgaaa aaggacaagt tgttgtcctg cttggacctt ctggctctgg gaagtccact
    23041 cttatccgta cgatcaatgg tttagagact gttgacaaag gaagtctcct agtcaatggg
    23101 caccaagttg ctggtgccag ccagaaagat ttggtacctc ttcgcaagga agtcggcatg
    23161 gtttttcaac attttaacct ttatccacac aaaactgtgt tagaaaacgt aacacttgca
    23221 cccattaaag ttctaggaat tgataaaaaa gaagctgaaa aaaccgccca aaaatatctg
    23281 gaatttgtaa atatgtggga caagaaagat tcctatcccg ccatgctatc tggtggacaa
    23341 aaacagcgga tcgccatcgc tcgtggtctt gctatgcatc cggaactcct cctctttgat
    23401 gaaccaacat ctgctcttga tcctgagact atcggagatg ttctagcagt tatgcagaaa
    23461 ctggcgcatg atgggatgaa catgatcatc gttacccacg aaatgggctt tgctcgagag
    23521 gttgcggacc gcattatctt tatggccgac ggagaagttt tagtagatac gacagatgtc
    23581 gataactttt ttgacaatcc aagcgaacct cgtgcccaac aattcctcag caaaattatc
    23641 aaccacgaaa gtgacaaagt caaataagga ggcgcctatg aaaaaaaaat tctttttatc
    23701 agcattattg attagccttt tcggccttgc tgctgccaaa ccagtccagg ctgatactag
    23761 tatcgcagac attcaaaaaa gaggcgaact ggttgtcggt gtcaaacaag acgttcccaa
    23821 ttttggttac aaagatccca agaccggtac ttattctggt atcgaaaccg acttggccaa
    23881 gatggtagct gatgaactca aggtcaagat tcgctatgtg ccggttacag cacaaacccg
    23941 cggccccctt ctagacaatg aacaggtcga tatggatatc gcgaccttta ccatcacgga
    24001 cgaacgcaaa aaactctaca actttaccag tccctactac acagacgctt ctggattttt
    24061 ggtcaataaa tctgccaaaa tcaaaaagat tgaggaccta aacggcaaaa ccatcggagt
    24121 cgcccaaggt tctatcaccc aacgcctaat tactgaactg ggtaaaaaga aaggtctgaa
    24181 gtttaaattc gtcgaacttg gttcctatcc agaattgatt acttccctgc acgctcatcg
    24241 tatcgatgcc ttttccgttg accgctctat tctatctggc tacactaata aacggacagc
    24301 actactagat gatagtttca agccatctga ctacggtatt gttaccaaga aatcaaatac
    24361 agagctcaac gactatcttg ataacttggt tactaaatgg agcaaggatg gtagtttgca
    24421 gaaactttat gaccgttaca agctcaaacc atctagtcat accgcagatt aaggaggata
    24481 ccctatgaca gatttatcat cttggacagc ctattttcag gattttggac aatttttcaa
    24541 tggtttcctc tttactcttg ccctagcgat tggatccttt atcctcgcca tggtcttagg
    24601 aatcttcttt ggtgccatgt caaccagtaa acgtccaatt ttacgcattt tagctcgcat
    24661 ctttgttgaa ttttaccaaa atactcccct cttggtgcag tttgttattg ttttttatgg
    24721 cctacctctt atcagtgacc atatcatcat gattccaatt tattggacag ccgttctctg
    24781 cgtgggactc tatcacggcg cttatatcgc tgaggttatt cgttcaggga ttcagtctat
    24841 tcctagtggt cagatggagg ccgccttgtc gcaaggtttt acctatatca gtgccatgcg
    24901 cttgattatc ttgcctcagg ccttccgcat cattctccct ccattgacca accaaattgt
    24961 taacctcatc aagaacacct ctactgtagc tatcatctct ggagtagact tgatgtttgt
    25021 gactaagtct tggtcggctc tcaacggaaa ctatatccca gcctttttag gtgctgctct
    25081 tctctacttt gccctatgct tccctgttgc ccagtttggt cgcaagatgg agcaagccaa
    25141 caaaaaagcc tattcacttt aggaggttac tatggaatct attttagaag ttttaacccc
    25201 agataaccta gtctttatct ttaaaggatt tggcttgacc ctctatattt ctctgattgc
    25261 catcatcctc tctactatca tcggtacggt gctagctgtc atgagaaatg gcaaaaatcc
    25321 tgtcttgcga atcatctcca gtatttatat cgagtttgtg cgcaacgttc ccaaccttct
    25381 ctggattttt actatctttt tggtgttcaa aatgaaatcc acaccagcag gtattacagc
    25441 ctttactctc tttacatcag cagccttggt tgagattatt cgaggcggtc tcaatgccgt
    25501 agacaaggga caatacgaag caggaatgtc acaaggcttc acctcagccc aaatcctcta
    25561 ctacatcatt ctcccacaag ccatccgcaa aatgctacca gccatcattt ctcagtttgt
    25621 taccgtgatt aaggatacca gtctcctcta ctctgttatc gccctacaag aactctttgg
    25681 agccagccaa attctcatgg gccgttattt tgaaccagag caggtcttca gtctttacat
    25741 cctgattgcc ctcatctact tcagctttaa cctagcaatt tctagcctgt ctcatatgct
    25801 agccaaacgt tggcaacaag ctgcagaata atactcttcg aaaatctctt caaaccacgt
    25861 cagctctatc tgcaacctca aaacagtgtt ttgagcaact tgcggctagc ttcctagttt
    25921 gctctttgat tttcattgag tataaacagc cactctccag ttcaattgga gagttttttg
    25981 atgagagtag atatttatag acctcaattt gacaccatac attttctatg ataaaatgta
    26041 acaaattcat ttacaacaaa tcgaaatcta aatgaaatgg aattttctat gaaatcagtc
    26101 aaaggactac tctttatcat agctagtttt atcttgactc ttttgacttg gatgaacact
    26161 tctccccaat tcatgattcc aggactagct ttaacaagcc tatctctgac ttttatccta
    26221 gccactcgtc tcccactact agaaagctgg tttcacggtt tggagaaggt ctacaccgtc
    26281 cacaaattca cagcctttct ctccatcatc ctactaatct ttcataactt tagtatgggc
    26341 ggtttgtggg gctctcgctt agctgctcag tttggcaatc ttgccatcta tatctttgcc
    26401 agcatcatcc ttgtcgccta tttaggcaaa tacatccaat acgaagcttg gcgatggatt
    26461 caccgcctgg tttacctagc ctatatttta ggactctttc acatctacat gataatgggc
    26521 aatcgtctcc ttacatttaa tcttctaagt tttcttgttg gtagctatgc ccttttaggc
    26581 ttactagctg gtttttatat catttttcta tatcaaaaga tttccttccc ctatctagga
    26641 aaaattaccc atctcaaacg cttaaatcac gatactagag aaattcaaat ccatcttagc
    26701 agacctttca actatcaatc aggacaattt gcctttctaa agattttcca agaaggcttt
    26761 gaaagtgctc cgcatccctt ttctatctca ggaggtcatg gtcaaactct ttactttact
    26821 attaaaaatt caggcgacca taccaagaat atctatgata atcttcaagc cggcagcaaa
    26881 gtaaccctag acagagctta cggacacatg atcatagaag aaggacgaga aaatcaggtt
    26941 tggattgctg gaggtattgg gatcaccccc ttcatctctt acatccgtga acatcctatt
    27001 ttagataaac aggttcactt ctactatagc ttccgtggag atgaaaatgc agtctaccta
    27061 gatttactcc gtaactatgc tcagaaaaat cctaattttg aactccatct aatcgacagt
    27121 acgaaagacg gctatcttaa ttttgaacaa aaagaagtgc ccgaacatgc aaccgtctat
    27181 atgtgtggtc ctatttctat gatgaaggca cttgccaaac agattaagaa acaaaatcca
    27241 aaaacagagc ttatttacga aggattcaag ttcaaataag taatcatact ctcctgggat
    27301 ttcccaggag agttttttat agccaaatga aataagacag gaacgatgga attttggcat
    27361 tcaaatcaat tgataagaat gttttatagt ggagtgaaat aggatacgaa caaattgatt
    27421 aggaaaatca aatgaattta tagaaatctt ttagcagtta tgttgtccta ttctagtttc
    27481 aaaacgctat agaagcagca ttgtgctagt ctagattcag tttactatac taaaacgagt
    27541 agcttgaaat caaaaaaccc accctcacag gcaggtttta tctgtattat tcagctagat
    27601 tatgctttac cttctgaacc gaatacgtcg atacgttctt caaccgatgc ttggatagct
    27661 tttacaccgt cagccaagaa tttacgtggg tcgaagagtt ttttcttgtc gtattctgct
    27721 tcgtttgctt cgtagtcacg agcaaattta cgagttgcgt tagcgaatgc gatttggcat
    27781 tctgtgttaa cgttaacttt ggcaacacca agtttgatag ctgcttggat ttgctcatca
    27841 ggaatacctg atccaccgtg caatacgatt gggaatcctg gaagagcttc tgtcaatttt
    27901 tgcaagtggt caaggtcaag accttcccag tttactgggt aaggaccgtg gatgttaccg
    27961 ataccagctg ccaagaagtc gataccagtt tcaaccattg ctttagcgtc ttcgattgga
    28021 gccaattcac ctttaccgat gattccgtct tcttcaccac cgatagtacc aacttcagct
    28081 tctactgaga tacctttagc gtgtgctttt tcaacaactt ctttagccaa tttaaggttt
    28141 tcttcaactg gaaggtgtga accgtcaaac atgattgaag tataaccaac ttcgatacac
    28201 tcaagtgcat cttcgtagtg accgtggtca aggtggatag ctactggtac agtgataccc
    28261 attgattcaa caaggttagc gatcaagttg cgagcaactt tgtaaccacc catgtattta
    28321 gcagcaccca ttgaagtttg gatcaaaact ggagcttttt tagcttctgc tgcgcgcaag
    28381 atagcttgag tccactcaag gttgtttgtg ttaaatccac caactgcata accgttgtca
    28441 cgggctgctt ggacaaattt ttctgctgaa acgattgcca ttttatcagg cctcctgtat
    28501 atttttatgg gtcatcccat ttacattgtt cattttatca ctttttgcca aaaaaatcta
    28561 gtttttcccg cagtttcgat tgattttctt ctaactccat ctatgtaaac cctttctctc
    28621 cctagtcttg gacgactttt ggaaaatcta taaagaaggt taaacgattc tcctccatct
    28681 cgaaacgata agctaatttt tcatgttcta atagactctt aaccacaaag agccccatac
    28741 cagacccctt gaccttgcga ctggcattgt cagaaaaaga ctgggctagt ttttcttgtt
    28801 cctctgagct acagctattt tcgataaaaa gttctccttc tctttctcca attcgaacta
    28861 agccacctgg aacagagtgc ttaatggcat tgctgatgag attagaaaga atcaacttca
    28921 taactgatgg gtttagataa gcctgctgat gggtcaaact attgtctatc tggagctctc
    28981 tttccttggc tagcaaggca taatctttga ccagattttg cgtcatctgg aggaggtcaa
    29041 ttgtttccct atcatctcgc aattcctgca cagaagagag ggaaagtatc tgcagaacat
    29101 ggtgattgag ttcatccaca atccccaagg caactcccag atactggtct ctatccttat
    29161 aacgaccgat attctctctc atattttcga ttaggatttt caaactagcc agcggtgttt
    29221 tcaattcatg agaagctcct cgtaggaatt cgaccttcat cttctccagc tggagaatgg
    29281 cttcattctt ttcatgcaag tccgcaataa cagtcaagag atgctggtag aggctattga
    29341 tttgttcctt gagattacct atctcatcct tagaatccac gcgcaatcgc acttgggcat
    29401 ccaggtacat catccgacga gtcacccgct tgatttccaa aatcggtgca acaatagtcc
    29461 gagcgtagat gtaggccacc aagagggaaa tcagaaagga ggccagcaag gtatagggaa
    29521 gaaactggag actgatttgc tccgcttcct tttgtaaatc catggaagct agaaactgga
    29581 gaatcatagt accaccgtct tgcgttttca cctcgcgctc ctcaataaag agagaggttg
    29641 tctggcggtc tgtgtccaga ggaagactgt ccttgacttc taacttgtcc tcggtcatct
    29701 cacctttgac ggtccccttg atatcactag tctgggaata caagtctaac acttgctcga
    29761 tactctgcct atctttccct tctagggact gggcaatggc tgttgccttt tgaccaatgg
    29821 tttcctgacg atgactcaga taagtcgaag gaaaaagaaa ataaatagct aaatgaaggc
    29881 agataaccag aacactaaat atcgagaagg tatagataaa tatctttgca aataaacctg
    29941 ttcgtttcat tttcgctcca atttataacc aacattgcgc acagtgagga tacaatccaa
    30001 gtctagcttt ttccgcaatt ccttgatata aacatcaata acacggtcaa agggaacctc
    30061 atctgtcgct ttccagacgg catcgataat ctgagatcga gtcaaggccc ggccttcatt
    30121 tttcactaga tagtccagaa tttccaactc tttggcattg ataggcactt cttgacctgc
    30181 gatgcttgca ctgtagcttt caaagtccac cttggtatcc ttgtaagaaa agattcgtcc
    30241 tgtatcgtag tagcgcttga aaatcgcgtc caccctcact tttaaaaggg agagggagaa
    30301 aggtttttcc agatagccat ctgccaaaga ggcaaaggca ctcatcttgt attcctcatc
    30361 ctgaaaagct gtcaacatca agacaggaac ctgactggtt ttacgaatct cagctaggac
    30421 ttctaagccg ttgagcttgg gcatctggat atccagtaaa accagggcca cctcatagct
    30481 agaaaattgc tccagagctt cctgaccgtc cgctgcctca atagtttcat agccacaatc
    30541 cgtcaaataa tcactgaccc cctcacggat catctcttca tcttctacaa ttaaaatttt
    30601 catactttaa ctgctctcta ttttttattt ttcttagaat aaatacctac tctattttct
    30661 attatagtct cttgctggcc ttttgtctgt aagtaactga ccactagata aaacgttgtg
    30721 aaattccttt ctcataaatt ccataacttt agtatattat atttaagcac taaagtacaa
    30781 agaaagcaac tgaaagcaat gattttcacc actgctttca gatttatttt gaattgttaa
    30841 atagccattc ctatccacta ttcttgaata gaaacacaag atgcaatctt tattccagac
    30901 tcattttttc aaatttattc accatccagc aagagttctt ttggttgttt tctaaggaga
    30961 ttgcttgaag caagcgccat aacgagaacc actagaacca aggcaaggac aaaaatgatg
    31021 ataaagtctg atgtctgaat ggaaatgtct aggctcgaca aggtcttgct aaagccatct
    31081 acttctgcac caccaccaag gttagaggct tgagccgcct tactagcctg tttggcaaca
    31141 cctgaagtca cattggcaag gacagtgttt ccaattgcac gggcagtgta attagctagg
    31201 aagtaagcag aaactagagc agggatagca atcaagatag attcggtgat gaattgaccc
    31261 aagatacttg cctgcttgag gccgatagag aggagaattc ccacttcctt gcgacgggcg
    31321 ttgatccaaa ggctgagcaa gagggcaagg aggagaactg agaagctcaa gctaccccag
    31381 aagaggaggt tggccatctt gtacatacca gagatagatt gctcaagagc tgggtagtta
    31441 gaggagctct tgacgagtgt gtagctcttc cagttgatac cactgatgcc attcaactct
    31501 ttcataacat catccaagtt cttgtctgct gttacaaaga aggttgcgtc cccataaatg
    31561 gctgtgtctt ctgtgtatcc ataaagtttt gcagcagtgt gaatgtctgt aatagctgtg
    31621 ttttcgtaaa gttcttgtga gtaggttact gctgacttat tatgaccatc aaagagtccc
    31681 ttgattgtca cttcaactgt ttccttggct cctttttcat tatctgcatc gtagatatta
    31741 gagtccagtt taaccttgtc ccctactttc cagccgtgtt tggctgccaa gtccttgtgc
    31801 aagaggattt tatccttgtc gtcgttggtt aagtgctctc cttcgactag tttataagaa
    31861 ccagagacaa acttgtcttc tttagaggag tcattgacac ctgtaatcat caagctactt
    31921 ccaaaacgtt tggcacgatc agcagtgaga ttcttcttgg tttctggcgt ttcaatcagg
    31981 tcatatccag tcaaatctcc gatagcgttg atacgtttga cataagactc gatggccttg
    32041 ttttcggtga tttttttgat gtcttcaccc ttgatattcc cagcaccacg aggcgttcct
    32101 tggttgacgc gacgattgat ttgcatggag aagctattgg tgatattttt aaaggtctcc
    32161 tgagaagcct tggcagtagc tcccttgatt gacaagccga ccaaactcaa gctcgccatg
    32221 aggagaataa tcaggaagat gacaatcgat ttgaaaaact tccttgtaac ataggcaaat
    32281 gcgttgtgta acatagattc cctttctaga ttttgtttta atcattctat caaaataagc
    32341 tcaaattatt tactagtatt gcgcgtttca gtcagtttct tatcctttaa ttcaagtgta
    32401 atatctgacg cttgtgccac ttctttactg tgagttacga caatcacaca tttacctgtt
    32461 ttctgggcaa gtgatttgag tagttcgaca atatctccag cagttttagg atccagattt
    32521 cctgttggct catcagctag aataactgga gcttctgaga ccaaactgcg agcaatggca
    32581 acacgttgct gttgaccacc tgataactgg agaacattcc gcttgatctg gctttcatcc
    32641 aaaccaagct caagaagtgt attcttgctt gcctttttgt tgaccaatcg gatattttcc
    32701 agcggagaaa gataatctat caagttataa ttttgaaaga ccagggaaat atggtgcatg
    32761 cgatggtaag aatagccctt cttacgaata tcctctcctt gaaaaaggat agaaccttca
    32821 acaggactat ctagaccagc aagtagggac aagagtgtgg attttcctgc tcctgactcc
    32881 ccaataatac tgtaaaattt tccaggttca aaattataat cgatctgata taggactgct
    32941 tcagcagtat tcttataacg gtaggtaaca tcttgtaatt gtaataaagt catgatttct
    33001 ccttcttaac taatagatga taaaatttct ttcggtgatt ttctaaataa gaataggaaa
    33061 caaagggcta cagataagca actaagcaga actagaaaaa cataggattc tgcaaaagat
    33121 aagatgctag ttgataaact gcttgctttg gctagtgtat cttgtaagct tgcctgatct
    33181 ccacttgcta gtagagtttg gagtaggtaa gttgtgattc cgtttcctgc aacaaatgct
    33241 ggaagcaaag ctccaagaga taccaaaact acctctaaac agaattgtag gaagatcgag
    33301 ctcttgcctt ttccaagtgc aagtaaaatc cccacttcat agacccgttc tctcaaccag
    33361 agagacaaaa ccagaattaa ggctccagct cctgctatca acatcccata aaggaagatg
    33421 gtcaggaagg tttggaaagt tgcaactgag tctttgattt gttcaaaagc cttgttttcc
    33481 ttttcgactt ggtagccttg attttccaag gccaagtttt ctacctgctt catgagtccg
    33541 tccatttcct taggattttc tacatagaag cgtgctgcac tgacttgagc ttcactattg
    33601 cccaaaaggg tttggctact ttcatagtct gtaaagactt gattttcact gaagtcagaa
    33661 gacaagcctg tgaatttctc ttgtttttta ccagaaaaga tgccaataat ctcaaactct
    33721 actgtttgtc cttttccaga ttcagactga ccagcatcca agccaatctt gtcatgaagt
    33781 gaaagaccgt tcttcttagc caattcttcg tggataagga ttttcttgga atcccctttt
    33841 tgaaggtgtc gcccttcttt tagattgaaa gccgaactgg taaaggttac atccttggat
    33901 gaatcctcaa gagccgttaa gctaaccaag ttattgtctg cagctgataa atcatcacgc
    33961 tccacgctct gctctccagt cactgcttcc ttgtctttta gttttgcgac cgtctcaagt
    34021 tcaggagaga cattttccag ccccttaatc ttgcttacag atgctaggtc tgacaacttg
    34081 aatgtctgac cattctctat cttcttaata gaaaaagatg tattgagtga tttataaaga
    34141 ttgctttcta ctgttttgtt ggacttcatc agagtcaaac aggctgaaat tccggccaat
    34201 aagaccaata aaatcagaaa taaaataaaa cttctcagtc gctttctgct gacataagcc
    34261 caagatcttt ggattggatt catttgtcac ctccatattt gtaagactat tataaaaccc
    34321 aaatatgaaa tgtttatgaa atacgaaaaa aaaatatcga gtaggggata atctctagcc
    34381 cctctcacac caccgtacgt gccgttcggc atacggctgt tcaactaact tttaacgcat
    34441 gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg tttttcaagg actggttttg
    34501 atatagcacg tttaagtacc gacttctgag ctactatagt agattgaaac tagaataata
    34561 tacctctact tctaaaatat tgttagaaat cgatttgact tccctgatcg attcgtccta
    34621 ttcttatttc attttaatat aattgatagt ggtcgcccca gccagatacc ttatctgcta
    34681 tccatttagg aacccctaac ttaagcaatc cccataatcg tctcgatttc ttcttccatt
    34741 gcttccagat aatcactcgt aggcgagtac gcaagcgctc atctatgcta gtgactatac
    34801 ttttcatatt tataattcat tcctttcgtt tcactcaagg cacaacacag aatgaaaaag
    34861 tgttgtgatc tttattttgt tttataataa tagtgagaaa gcctatcact actacaaatc
    34921 acggggaggt gaataagtga gtggtacagc cactacctcg catattttgt cacatcattt
    34981 aacggtgcat aataagttgt accatctgaa taagttgcta caatatcatt tgcatgctct
    35041 ccttcacctt tagcaaaggt tggagctcct gctggatgat ttttatttgc ctctttcaat
    35101 ttttcaataa tggcattttt ttctgtatct tttatattat caggattttt cactaagatt
    35161 ttgtctggat atgtcggttt agcagaaaca atttttactg ttatttcttt tttattcgaa
    35221 gcacttgtcc agtttccagc attatcttta gcatttaatt ttacagtaat tcctgaacta
    35281 ggaacttcag tagcaggttg attatcaaca ttattcaact ttaatttcaa aagagctgtt
    35341 gcatcagacg ttttatcaat cgttgtatat aatgatgaat tgttattata accagtttct
    35401 tcatatttag ctgtttgtga gctacttgaa acagaactga aattatgccc actacctccc
    35461 tgattatctt caatgcttac gtctaaatga acttccccac tattatttgg cttagcaaca
    35521 actgttatag taaaataaca taaaatttgc ataaatagat tagggaaatc aaagcaactt
    35581 ctaggaatgt tttatactct tcgaaaatct cttcaaacca cgtcagcttc accttgacgt
    35641 actcaagtac agcctgcggc tagcttccta gtttgtactt tgattttcat tgagtattat
    35701 cagtcacagt gtactttccc agcatcaagc cactataact ctgcacataa aaatggagaa
    35761 gatggcaatc ctcttctcca aatattaact tctttacaaa ccaactatag ttgacaaaga
    35821 acctaaaatc aattgataac acaaggtcag gtcggtcaac tctttcaact gaagccctgt
    35881 caactcttcc catttatcaa tcttgtattg gagagaattg cggtgcagat agagttgctg
    35941 ggctgtttta gtgagaacag cactattttc ccaaagagag agaatgattt cctgaatctg
    36001 atcttgatcc aaaatcatct ggtgtagaca ttctttaatt ggcttcaagt ccacgagtct
    36061 ttctcccata ctccaaagat agagctgaga aaaagtatga acaccttggt gaccctgacg
    36121 ccaccatgtc ttgaacaaat cccgctcagc tttgattaag tctgataggg cttgatgtcc
    36181 tgtctgagac caaacctgac ccaacatgat agaaagacga agtccaaaat catactcaac
    36241 cgcttcaatc gtatcactta aaatatctct tacagaagtg tatttgtctt gttgaagcac
    36301 gaaaacataa tcctgagctc cgacctgtag cactgtctga caattcggaa aaagagtccg
    36361 catcatatct agccaagaag tcagattttc ctgctgaaaa taagaaagat ggcaataaac
    36421 caactgaatc tttttaaaaa cttgcggtgc ctgtcccttg ccttcaacca gataggaata
    36481 ccaagggttt agcgaacgag cctgctcctg ctgggtcaaa agggcaacca actgcttttc
    36541 acgctcgctg agcccagctt cctccagcaa aatccactgc tgagaagcta aagggagcgt
    36601 gagatagccc tctttctcta ctggttggtc tgaaatccga gcctcaggaa accagtcttg
    36661 tagttctttt tccctcatgt tctagccctc cactttttgg atgcaccatg aaaccaaact
    36721 ctcaagacgt tccagattct cagtcatatg gagatagccc ataaccgctt caaatcccgt
    36781 ggacatacga taagtcacga catctgcatt tttagccttt gtgtggctat tggtattgcg
    36841 gccacgtttg tagatttctt cttctttttc cgttaggacc tgctcctcca acatgagagc
    36901 aatcaggcga gcctgagcct tggctgacac atacttggtt gcttcttgat ggagtttatt
    36961 gggtttggtc atacctttga ggatgaggtg gcggcgaata tacatagaat acaccgcatc
    37021 tccctcaaag gctagcgcaa tcccgttaat gagattgaca tcaatcacgt gtccacctca
    37081 ctccatcttt tgtatccaat agtttaatgc cttgagcagc cagttggtca cggatttggt
    37141 ctgctgtctc aaagtctcga ttggcacgcg cctcttggcg tttttgaatc aagtcttcaa
    37201 tctctgcatc caaaacttcc tcaacaaaga caattccaaa aatttctaac atatctgcaa
    37261 gagcttgctt gacacttgca tcatagttcc ctgagttgat ccatttggtc atttcaaaga
    37321 caactgtgat accgttggca gcattaaaat cttcatccat agctgctaca aacttatctt
    37381 taaagttttg taactcttgg gcatccacgt ttcctgtaaa tggttgttcg taagtattct
    37441 tcagatactt gagattggtc tcggcatcgc gaactgcctt ttccgtgaag ttgataggct
    37501 tacggtagtg ctgggtcgca aagaagaaac gaagtacttg cccatcaaga gttttaaggg
    37561 catcgtgtac cgtaatgaag ttacccaagg acttagacat tttgacattg tcgatattga
    37621 caaagccatt gtgcatccag tagttagcaa aagccttgcc tgttttagct tcagattggg
    37681 caatttcatt ggtgtggtgc ggaaattcta ggtcagctcc accaccgtgg atatcaatgg
    37741 tatcacctaa aatctctgtc gacatgactg aacactcaat gtgccaaccc ggacgtccag
    37801 gtccccaagg actatcccaa gaaatctcac ctggtttgga agatttccat agagcaaaat
    37861 ctacaggatt ttccttacga gccgtttctt catcggtacg acctgaagca cctagatcca
    37921 aatcttccaa ggttttatta gccaatttgg catagttgtg ggatttttct acacggaaat
    37981 agacatcccc ttgactctca taggcaaagc ctttctcgat caagtcttcc acaaaacgga
    38041 tgatgtctgc cataaactcc actacacgcg gatggcgagt cgcaggtttc acgcctaagg
    38101 ccgtcacatc ctcacgaaag gcagcgatgt acttatccgc aacctcctga ggcgtgatac
    38161 cttcttccct ggcacggttg ataatcttat catccacatc tgtaaaattg gaaatatagg
    38221 caaccttata cccacggtac tcaaaatagc gacgaatcgt atcaaaagct accgtcgaac
    38281 gggcgtttcc cacgtggata tagttgtaca ccgttggccc acaaacatac atcttgatct
    38341 tgccgtcctc aatcgggaca aattctcgca aatcacgaga catggtgtca tagattttaa
    38401 tcataaatca taatcaggaa agctgaaatc caagaacaat tagtttcatc actaaaagtt
    38461 caagtaaatt tcagtccgaa tatctctaca cttcggaatc ccttgctcct ttctcattca
    38521 gataaaccac ctgagtctgt ttgacaaagc caattttttc atacaaacgt ttggcaccta
    38581 cattgctatc ttccactgca atctgaaatt ccttgtcatt ttgctcaatt agttggttga
    38641 cgagggattt tgctaagtag cttccatagc ctttcccacg ttcaggttcc gatattgcta
    38701 aaccgtagaa gtaattcgta ttagtcgata aatctaccgt gcaagtccca ataacctgac
    38761 cgtcttttaa caaaatatat aagcgacttt ctggatcctt cagagcttca gcgacatatc
    38821 tatccacaac ttctctcgat tcatgttcct ctgaaaatgc ctgaaatttt aattgactaa
    38881 tttgatcctg atacgaacta tctgctaaca aaacttcaag atgggaaaca tttgctaacg
    38941 gataaggtct tctatcctta cctaaccaag tttctgtctc ttcatcctcg attagtcccc
    39001 agttactggc aaagtcagga tgattctcta aaaaaatacg ttctgtctga aaagtgactg
    39061 accgaatggg gaaagaagct atttctctct caaaactagt aaacaatgca cgcgcaatcc
    39121 cctgacggcg atgacctgga tgaaccagta tcgttacttc tacatcttgg tcatctgcat
    39181 agacagttaa taaaccaaca agttcgcctt tttcataata aaggaaaaag gcgggcatgt
    39241 ttgggtcaaa attaagcatg ttagagagat agggatcgcg ataggtaccg tcatagtttt
    39301 ggcaacagtt aattactttt ttcgcctcag atagctcctc ttggcttaac ttgtttcttg
    39361 cttgaatcat ataggtatcc tctacaaacc agacgatctg tgactggcat ctttagcctg
    39421 ctcgagttta ttgacataat actctcgttt ttcttcgact tcgtgaatga caggctcatc
    39481 tttcttacca tgaagacgga caatcttggc cggaataccg acaaccgtca cgtcactagg
    39541 tacatctgct acgacaactg ctgcagcacc gaccttggca ttttcaccaa tttccacagg
    39601 cccgataact tgggcatggg ctgatatgag ggctcccttt cgtacagtcg gatggcgttt
    39661 gccacagtct ttccctgttc ccccgagagt cactccgtga tagagaagaa cgcctttttc
    39721 aacaatcgct gtctctccaa tcaccagacc agaaccatgg tcaataaaaa cacctgaatc
    39781 aatctgggct cctggatgaa tctcaatctg agtccaaaag cgccaaaact gactgtacat
    39841 acgagctaat agtttgaagc cgtgcttcca gagaaaatgc gagagacggt gggccgccaa
    39901 ggccttgaca cctggataag tcagcaaaac ctccaaagtg gtgcgggccg ctggatcatt
    39961 ttcttttaca atatcaatgg tttcgcgcca ccaccccata catttctcct tttcttattc
    40021 tgaatctttt ggtgtttctg taaattcttt cttaggtttg tgatcctttt gatgacgtgg
    40081 gcggtgaggg cgctcagact tttcaccttt ttcatcatgc tcaggttttg gcggacgagg
    40141 tagaagagcc ttcatagagg catcgatacg gcctttttca tcaatcttga taaccttaac
    40201 atcaacttca tccccgattt ctaccaaatc ctctacacga ttggtacgag tccaagccat
    40261 ctcagagata tgaacaaggg catctgtctt atcaaagagg ttaacaaagg caccaaattt
    40321 ctcgatacga acgactttag cacggtaaac ttcatccact ttggcttcac gaaccaaacc
    40381 agcaataatt tctttggcac ggttaatagc atcttggtca ctagagtaga tagacacatt
    40441 tccttcttcg tctatatcaa tcttaacacc tgtttcagcg ataatcttgt cgatggtttc
    40501 tccaccctta ccgatgacaa tcttaatctt gtccacatca atcttgatcg tatcaatttt
    40561 cggagcagtt ggagccaatt ctggacgaac ttctggaatg gttgcttcaa tgacatcaag
    40621 gatttcaaaa cgcgctttct tggcttgagc aagagcctcc gtcaagattt ctgcagtaat
    40681 cccttgaatc ttgatatcca tttgaagggc tgtaatccca tcacgagtac ctgcaacctt
    40741 gaagtccata tctccaaagt gatcttccaa accttggata tctgtcaata ctgtgtagtt
    40801 atttccatct gagataagtc ccatagcaat accagctact ggcgccttga ttggcacacc
    40861 accagccata agggcaagag ttcccgcaca gatagaagct tgagatgaag aaccgtttga
    40921 ttccaaaact tctgctacta gacggatagc gtatgggaat tcttccaagc ttggcaagac
    40981 ttgagcaaga gcacgctcac caagagcacc gtgaccgatt tcacgacgac ctggcgcacc
    41041 gtaacgacct gtttccccta cagaatattg agggaagtta tagtggtgca taaagcgttt
    41101 cttgtactct ggatccaaac catcaatgat ttgagtttct cccatcggag ccaaggtcaa
    41161 gactgaaaga gcttgagttt gcccacgagt aaagagacct gaaccatgta cacgaggaag
    41221 gaagtcaaca accgcatcca aaggacggat ttcatcgacc ttacgaccat caggacgcac
    41281 cttgtcttct gtaattaaac gtcgcacttc tgcgtgttcc atttgttcca agatttcagc
    41341 cacatcacgc ataatacggt caaattcttc gtggttcgca tatttttctt cgtaaacggc
    41401 agtcacttgg tctttcactg cttgagttgc agcttcacgg gccaatttct cttctacttg
    41461 aactgccttt tggaggtcac tgttgtaggc tgcaatgatt tcagcttgca attcagcatc
    41521 cacgtgaagc aattccactt ctgctttttc tttaccgaca gcagcaacga tttcttcttg
    41581 gaaggtaatc aattctttga cagcttcgtg ccctttaaga agcgcttcca acatgatttc
    41641 ttctgacaat tctttggcac cagactctac catgttgata gcgtgcttgg ttccagctac
    41701 tgtcaattca agaagagatt gctctgcttg ttcttgactt gggttgatga tgatttggcc
    41761 atctacatat cccacttgta ccccagcaat tggtccgtca aatggaatat ctgaaataga
    41821 cagtgccaaa gatgaaccaa acatagcagc cattggtgca gatgcatttt catcataaga
    41881 aagcactgta ttgatgactt ggacttcatt acggaaacct tccgcaaaca taggacgaat
    41941 cggacggtca atcaaacgcg ctgtcaaggt cgcatctgtt gaaggacgtc cttcacgttt
    42001 cataaagcca ccaggaaact tcccagccgc atacattttt tcttcgtagt tgacttggag
    42061 tgggaagaaa tccccagttg ccattttctt agacataacg gcagcagtca agacagttga
    42121 ctcaccgtaa cgtacgacaa cagagccatt tgcttgctta gcaacctgac cagtctctac
    42181 aattaactca cgacccacaa aagtcgtttg aaacacttgt tttgccattt taatcccctt
    42241 tggattgatg aaattatacg ccttgcctac aaagatcaag ataccaagga cgtcaaaagc
    42301 aaagtaaaaa taggaaactg acgaagtctt cgatgaagac aagacagttt atctttttta
    42361 cacagctttt cggccgtgtt caattacaca agatattttg gacggttcgg cttgccgaac
    42421 atttctgtag aaaaatagga aggtgacgtc gcactcgacg agtgctagga agcttatctt
    42481 ttttcctaag aaatgagacc aaaattcaat tactcaagat gctaagccgt caagcaactc
    42541 aaaggaagat aggaaatcga acgacggagc gactgctcct agggagattt atctttttcc
    42601 acagagttgt aggcaagttc agttttcaag atacatcatt agaaaggttt aatattaaag
    42661 tatctaaacc tttcacgcta attgctatcg ggcgattagc taaatgcttt actaactctt
    42721 tcgtcaaata acatcgattt gactcactcg tgtcgttaaa tcttacagtt taaatgcatt
    42781 gtattattta ataccttcat ctttgtatca agtacgtaca gaatctattt tatcatattt
    42841 ttcttaaaaa gtgaggtctt tgccattaaa aaggaaccat tcccctcacc tgagaagaat
    42901 ggtttgcttt tattatccta gagactggtg attaaacaag gcatgggttg cttgatggat
    42961 gtattttgct gtatcagcat tattcatcgt atagagatgc acaccggcaa catcctgagt
    43021 taccaagtcc acgatttggt ccactgcata ggcaagtcct gctgctctga gcgactcagg
    43081 gtcatgctca tacttgtcta agatggcttt aaatttgcgt ggaagatgga tattctcaca
    43141 agtcttcaag agtcggagag cctgatttcg attcagaatt ggcataattc ctgcatgaat
    43201 gggaacatca atcccagcca agatgcactt gtcctgaaaa tcatagaagc gctcattgtc
    43261 aaagaagagc tgagttacga ggctcgaaca gcctgcatcc actttcttct taagattttg
    43321 aatatctgaa atctgatttg gcgaatctgg atgcccttct ggatagcaag ctccaataat
    43381 atcaaagtga ggggtttgtt ccttgataaa ctcaatcaag tcggttgcat agcggaaatc
    43441 cttttgtggt tccacgtctg gaataatatc cccacgaaga gccaagattt tctgcacccc
    43501 aactttgtcc aagtcagcaa tagtttcagc aaccttgtcc ttagttagat aaatagctgg
    43561 caagtgggca atggtcggaa tcgccaaatc attttggata aagtcagcca aacgaaccgt
    43621 cgtttccttg atattaaatt tattattgct ggcagttaca ctgataaaat ggggagccaa
    43681 ctcctgcata tcctgcaagg ctgaaataat gttaccatta cccacggctg ggtttggagg
    43741 gaacacttca aatgagagtg acggtgtttg gcgtgacata tgtaataacc ttttctagtt
    43801 gatttctttt tgaacaacca ctgtatggag agaaatccaa tcttacaatt tctcacgcgc
    43861 agctttagct gcttcaacaa ggcggatcaa gctttctttt gtttctggga taccacgtgt
    43921 tttcaaacca cagtcagggt tgatccaaac tttcttgctt ggcactttag caaggatggc
    43981 ttcgattgtg ttgtcgattt cgccttcatt tggtacacga ggtgagtgga tatcgtaaac
    44041 cccaggtccc acttctgttt ggaagttttt cgctttgagt tcgtccaaga tttcaaggtt
    44101 tgaacggcta gcttcaaagg aaataacgtc tgcatccatg ttatcgatag ctgggatgat
    44161 atctgtaaat tctgagtaac acatgtgagt gtggatttgt gtgtctggcg ctactgttga
    44221 gtgtaccaag cggaaggcag gaatagccca gtcaaggtag tcttcgtacc agtcgctacg
    44281 gcggagtggc aatttttcac gaagagcagc ctcgtcgatt tggatgattt tcacaccagc
    44341 agcttcaagg tcaagtactt catccttgat agcaagggcg atttggagag ttgaatcctt
    44401 gatagagatg tcttcacgtg ggaatgacca gttaaggatg gtaacaggtc cagtcaacat
    44461 acctttaaca ggtttgtttg tacgactttg tgcatagcta gaccatttaa cagtgatagg
    44521 gttaagacga gtgacatcac cccagatgat tggtggtttt accccacgca taccgtatga
    44581 ttgtacccat ccatttttag agaagaggta tcctgacaag ttttgaccga agtactcaac
    44641 catgtcatta cgctcaaatt caccgtgaac aaggacatca aagtcaatat cttcttgcca
    44701 cttgatccat tcgtcaatcg tttcagcaag gaaagcatcg tactcttttt gagacaattc
    44761 acctttacgg taagccaaac gtttggcacg aacttctttt gtttgaggga atgaaccaat
    44821 cgttgttgtt ggaagagctg gaagtttgaa agcttcttct tggatagctt cacgttctgc
    44881 aaaggctggc aaacgagtgt agtctgcgtc tgtcaagcca gcgatacgcg cacgaagttc
    44941 agcattttca ccaacacgct cagtcgcaaa gagttctttg ttggctgcaa gagcttctga
    45001 accttgacca ttgcggatag catccaagtc acggatttca tccaattttt caactgcaaa
    45061 ggcaaagtgg ttcaagagtg ctggttcaaa ttcttcatta gcagttgtaa atggcacatg
    45121 aagaagtgag caagagcttg tcaaaacgat gttttcagct ggaatttgct caagaacagc
    45181 caagctcttt tcgtagttgt tgcgccagat gtttttacca ttgacaatac ctacatagag
    45241 agtcttgtca gctgggaagc cacctttaac gagttcaaga gttttcttac cttcaacaaa
    45301 gtcaagaccg atagcatcta ctggtaagtt tacaaggtca gcgtatacgt cacgaacatc
    45361 accgaaataa gtttgaagca agacttcaag accttttttg tcagccaaga gtttgttgta
    45421 aaggttcaag aagagagctt tttcttcagc tgtcaagtct tttacaagag ccgcttcatc
    45481 caattggatg caagtcgcac caagttcagc caatttagca aaaacttctt ggtaagcagc
    45541 cactaagcta tctacgaagt cgtctgcttt cacgccttct tcaaagtctg acaattgaag
    45601 gaaagtgaag ggacctacaa gaactggacg agtgttcaat ccaagttctt ttgcttcttg
    45661 gaactcatcg aaaatcttgt gaccagccaa tttcacttga gtgtcttttt caaatttagg
    45721 aacgatgtag tggtagttag tgttgaacca tttcttcatt ggaagggcgc gaacgtcccc
    45781 tttttctccc tggtaaccac gtcccaaagc gaagtagcgc tcaaggtcag acaagtccaa
    45841 gttttgaaca gatgcaggca ccacgttgaa aaggaaagcc gcatctagga agttatcata
    45901 gtgagaaaag tcatttgatg gaatttcagt gatgcctttt tctttgacaa tgttccagtg
    45961 tttagcacgc aagtcttttg ctgctgctaa aagttcttct tctgagattt cttttctaaa
    46021 gtatttttca gttgtaaatt ttaattcacg gaattcgccc aaacgaggga aaccgatgat
    46081 tgtagttgac atgatgtgtc ctccaaaatt tgttgttgaa actatcttaa cagaaaagaa
    46141 agcgtctgta taattgtaaa aaattagggt ttgatatagt ttgaaactat atatctgttt
    46201 cggacaaaag aaaaagactt gaagcaaacg tctcaaatcc tttgtatagc ttgttttata
    46261 gctgtatttt agttagaatg ctcaaacgcg ttattagtaa ttcttataag tgactatggc
    46321 ttgttattag aaaagactat aactgattct agtcaacttt ttccctgttc aagtgggacg
    46381 attgctagtg tctttcctaa actggctagg acttttaaga ctgtatccaa ctgaggacta
    46441 gtctttcctg tctccatcct agctatgaca ggctggctta ttccactgac ttcttccagc
    46501 tttttctgac tgattccttg ttcataccta gcctcaatca actcgctcat gatagccact
    46561 cgcatatcac tttcaaggat ttcctccttg ctaaagagct cagatggaca tccttccaat
    46621 tactcccaat agcactattc ttcatcactt aaccctcttt tttttacgtc tatgtatttt
    46681 taaaaaaatg agcgaattat gattcgatag attgaccagc gggtttaaag ttggtgctag
    46741 cctatttctt aagcgatttt ccttttctag gataaagcag atcctgcttg cttaacccca
    46801 attttccacg atgaatccaa tagtaaatgg ttgaaattcc cacgttaacc cctttagcca
    46861 tcaccatcat ttcaggcgaa aatttttgat tatgtatagt ggagaatctt ttcctttagt
    46921 tccttggtca agcttgattt cttgaccgag cgcttgcgat tgttttcata agactgttga
    46981 gcgtagtcgg cagaataaac ctctttgaag cgcccttttc caagacattg tcggactgtc
    47041 ccacgcttga tttcagtgtg gatagtttga ggagcttttc caagtagaga ggcaacttct
    47101 ctatttgatt ttccttcttt tttccatctt tcgattaagc gacggctatc gattgtcaaa
    47161 tgtttacctt ttgtagtata attgtcttgc atctctgtgc cttttaatca tttcaatctt
    47221 aaattggact ttttttactt gggttgtact taatctataa ggaagacaat aaaaagaata
    47281 tcaatcaagt aaagtcacaa agtcacatta gctccgagca accattgcaa attgaggtac
    47341 tcacacaatg attaaaacat ttctctctgc cctttcggtc attctctttg ttatccctat
    47401 catagcttat tctttttttc catcttctaa tcttaatatt tggctatcta ccagacctat
    47461 cttggcacag atttatgcct tccccttagc tactgcaact atggcttcta ttttaagttt
    47521 cgtatttttt tccctatctt tttacaagaa aaataaacaa atacggtttt actctggcat
    47581 tttgctctta ctatcgctca tattactatt attcggaaca gataaaaccc tttcttctgc
    47641 atcaaataag actaaaacct taaaattagt aacttggaac gtcgctaatc aaatagaagc
    47701 acaacatatt gagcgaattt ttagccattt tgatgccgat atggctatat tccctgaact
    47761 agctaccaat atcagaggtg agcaagaaaa ccagagaatc aaactattgt ttcatcaagt
    47821 tggactttct atggccaact atgatatttt cacttctcca cctaccaata gtggaatagc
    47881 tcctgtgact gtgattgtca agaaaagtta tggtttctat acagaagcta aaacttttca
    47941 tacaacacgg tttgggacaa ttgtattaca ttcgagaaaa caaaatatac cagatatcat
    48001 tgccttgcat actgctcctc ctctgccagg tttaatggaa atctggaagc aagacttaaa
    48061 catcattcat aatcaattgg cttcaaaata tccaaaggct attattgcag gtgattttaa
    48121 tgcaactatg cgtcatggag cacttgcaaa aataagctct catagggacg cattaaatgt
    48181 actgccacct tttgaaagag gaacttggaa tagccaaagt ccaaaacttt ttaatgcaac
    48241 aatagatcat attttattgc ctaaaaacca ctactatgtt aaagatttag acattgtaag
    48301 ttttcaaaac tctgatcata gatgtatttt tacagaaatc acattttaat tattttatat
    48361 aaaatcaccc ctctagtgtt cataaactag agggggaatt tgtatcatac tatcgtttaa
    48421 cgcacttctg cattcacttt ttcttcgagc gatgcttgga ttttttccat atagcgtgcg
    48481 acttcttcgt ccgttaagct atcttctgga ttttggaagg tcaagctata agccattgac
    48541 ttcataccaa gtcccaattt ctcacctgag aagacgtcaa agagtttgat atctgtcaaa
    48601 cgtttcacgc cggcagcttg gatagcatct acaacttctt gatgagtcac ttctgccttg
    48661 aggagaaggg caacgtcacg gctgactgct gggaatttcg tgatttccac aaatggaaca
    48721 gcaggttgga gcgccccttc gatggctgaa aggttaagct cagctacata cgtttctgga
    48781 atatcgtaag ccttggcagt gactggatgc acttggccaa ggaaaccaag aacttggtca
    48841 ccgagtgaaa tcacggctgt acgacctgga tgaaggctag cgatttcaga tgttgctgta
    48901 taggttactt ggagtcccaa acgagtaaat agggcttcaa ggattccctt agcatagaag
    48961 aaatcaactg gaactgctgc tgtttggaaa tctttttcag caaccaagcc tgtcaaggca
    49021 aaggcaaaac tgttgatttc atttggaagt tcttcttttg gattacctgt ttgttcaaag
    49081 acttttccaa tctcgtaaag agccaagttt ttattcttac gagccacgtt gtaggcaacg
    49141 gtatcaagga tacctgaaat catattttga cggaggactg aacgatccac agtcattggc
    49201 cacatgagtt cagtaaggtt acttggttga gccgtaaact caactgcttt ttcaggagtt
    49261 gtcagagcat aggtgatgat ttctgtcaaa cctgctcctt cagcaatagt acgaacttga
    49321 cggcggagtt tttgtgtggc tgtcaattca cctgctgtac catcgtcttt tggtagacta
    49381 gttggcaagc ggtcataacc atagatacga gcaatttctt caaaaaggtc agcttcgatt
    49441 gtgatatccc aacgacgacg tgggactctg actgtaaagc tgtctgcatt tccagaaaga
    49501 ccaaagccaa gacgacggaa gacgtcttct acatcagcat aagacagctc agttccgagg
    49561 acacggttaa catcagcaag ggttgaagaa acttctacat ctgaagtatc aagctcaccc
    49621 gctgaaacga tgcccttacg caccgtcgca cctgcaagtt ccgcaatcag gctagatgcc
    49681 gcatcaaggg cttcattaac tgttgccaca ttaattcctt tttcaaagcg agaagatgac
    49741 tcagaacgaa ggttcaggcg accacttgtc ttacggatag atttgccatt gaaaacagca
    49801 gcttcaagga caacacgact agatttttca gagatttctg ttgcttgacc acccatgaca
    49861 cctgcaaggg ctactggctt gtctgcgaca gtgatgacta ggtcattcac gtccaagtca
    49921 cgttcttcac cgtccaaggt caccaatttt tcaccagcac gcgcttcacg cacacggatg
    49981 tcagtccctt caaagttatc caagtcaaag gcatgcattg gttgaccaaa atagagcagg
    50041 atgtagttgg tcacgtccac tacgttattg atgggacgga tgccttcgtt catgagaagg
    50101 ttttgcaacc attgtggact tggtgcgatg gtcacatttt ccaagatacg agctgcatag
    50161 taaggcgcct tgtctgtctc aatgctgaca gaaagggcat ctgccgcagc ttcattagtt
    50221 tctgttagag taaattcttt aaagttgact gccttgtcat agatggctgc cacttcgtga
    50281 gccactccac acatagaaag ggcatctgca cggtttggtg tgatggaaag ttcgatgatt
    50341 tcatcatcca agtctaggta agaaaagact tcctcacctg gcacggcatc ttcaggcaag
    50401 atttggatgc catctgcgaa ttccttaggc acaactgagt cagaaatccc caattcacca
    50461 agtgaacaga tcattccaag tgactccaaa ccacggattt ttcctttttt gattttgtag
    50521 ttatcagcga tacgagctcc tggaagagcc accatgacct tgatcccagc acgcacattt
    50581 ggggcaccac aaacgatctg acgggcttct tcttcgccaa cgttaacctg acaaacatgg
    50641 aggtgagtct ctggcacatc ttcgcaagac aagacctcac cgacaacaat ttttgagaga
    50701 tcagcagctg gtgattcgac actctctacc tcgatccctg tggttgacat tttttcagcc
    50761 aactcctgtg atggcacatc aatgtccacc aattctttta accatttata agatacaagc
    50821 ataatttagt tctccagaat gaccattgcc acactggttc ttttcctttc ctatcatttc
    50881 aatagaagaa tcctcttctt accttaattt ctttctcagt aaccaatccg tatctacttt
    50941 ttgaccaacc ataaaatgat gttggctaaa tttttcaaaa ccatatcgat tataaaacgc
    51001 ttgagctttt gtattatgct cccaaacacc tagccaagcc caagaaaaac tattttttgt
    51061 agcaagttca agtgcgaatt caaacagttg cttacctatt ccaaatcctt ggaatttttg
    51121 tagcacatag aggcgttgaa tttcaaaagc gtcctctaat tctctctcag tttgagcact
    51181 tccccagttg actttgagaa aaccagctat ctcctcctca tgcataatga aataggtttc
    51241 agagtcagga tttcccaact cagttgacaa agttttcaga ctataagcct cttcaaagta
    51301 ttcctgtaac tgctcttccg tattatcata cgcaaaggtt tcacgaaagg cttgtttggc
    51361 aattttagcc aacacctcaa catctgccat ttctactttt ctaatcatta tttaaactgt
    51421 tctgagaagc ggacatctcc ttggtagaat ccacggatat cgttgattcc ataacggagc
    51481 atagctacac gctcttgtcc aagaccaaag gcaaaaccag agtatacagt cgcatcgata
    51541 ccactcattt caaggacacg tgggtgaacc ataccggctc ccataatttc gatccaacct
    51601 gttttcttac atacgttaca gccttctcca ccacacttga agcaagaaac atccacctca
    51661 acagatggct ctgtgaatgg gaagtaagat ggacgcaaac gaattttacg ctcttcacca
    51721 aacatttttt ggacaatcaa ctgaagcgtt ccttgaagat cagccataga gatatttttc
    51781 ccaactacca agccttcgat ttggtggaat tggtgactgt gggtcgcatc gtccgtatcg
    51841 cgacggaaga cacgccctgg cgagatcatc ttcaaaggac ctttagaaaa atcatgggca
    51901 tccatagcac gcgcctgaac tggagacgtg tgggtacgga gcaagatttc ttcagtgata
    51961 tagaaagtat cctgcatatc acgagctggg tggtcttttg gaaggttcat acgttcaaag
    52021 ttatagtagt cttgctctac ttcaaaacca tccacgactt gataacccat accgatgaag
    52081 atatcttcga tttcttcact ggtttgtgtc aaaacgtgac ggtgaccagt cgcaactgga
    52141 cgacctggaa gcgtcacatc gatactctcg ctagccagtt gagccgcgac tttcttttct
    52201 tccaagagct tagctgtttc ttcaaaagca gcagtcaaga catcacgagc ttcattgacg
    52261 tgtttcccga tgattggacg catctcagca gaaacatctt tcatcccttt gaggatttca
    52321 gtgagcgaac cctttttacc aaggacagag acacgcaaat cttgcatctc tttttcattt
    52381 ccagcagtaa tctgcttcaa gctagccagc gtttcttcgc gaagcgcttt taattgttct
    52441 tcaatagttg acatatttcc tccatcagtc tctcgtagat aaaaagaaaa ccacatgcca
    52501 aaaactccac tcggagcgtt gacacgcggt accatccgtt ttcatctgac aagtcagacc
    52561 ttcatttcta aatccatgcg caagtgaatt cacccagctt tcatatagag agcttgcagt
    52621 cacggctctc ctccctgata tacttccctt gggctactag tctttcagat tcctattcaa
    52681 ttactactta gtttatcaga tttttaccat tcttgcaaga cctatcttac ttctgcttgt
    52741 tagcttattc ttatctaact
//
LOCUS       DBERDS010000009        50020 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.009, whole genome shotgun sequence.
ACCESSION   DBERDS010000009 DBERDS010000000
VERSION     DBERDS010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 50020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50020
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.009"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            21..191
                     /locus_tag="ACL73E_000605"
     CDS             21..191
                     /locus_tag="ACL73E_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGS0800622.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            641..2656
                     /locus_tag="ACL73E_000606"
     CDS             641..2656
                     /locus_tag="ACL73E_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGS0800623.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTTGEGLLSYNLILLSISLFFTQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            2658..3290
                     /locus_tag="ACL73E_000607"
     CDS             2658..3290
                     /locus_tag="ACL73E_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800624.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4218..4631)
                     /gene="ndk"
                     /locus_tag="ACL73E_000608"
     CDS             complement(4218..4631)
                     /gene="ndk"
                     /locus_tag="ACL73E_000608"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGS0800625.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(4742..8419)
                     /gene="rpoC"
                     /locus_tag="ACL73E_000609"
     CDS             complement(4742..8419)
                     /gene="rpoC"
                     /locus_tag="ACL73E_000609"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGS0800626.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8452..12063)
                     /gene="rpoB"
                     /locus_tag="ACL73E_000610"
     CDS             complement(8452..12063)
                     /gene="rpoB"
                     /locus_tag="ACL73E_000610"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS0800627.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12479..12549
                     /locus_tag="ACL73E_000611"
     tRNA            12479..12549
                     /locus_tag="ACL73E_000611"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12511..12513,aa:Cys,seq:gca)
     gene            complement(12747..14078)
                     /locus_tag="ACL73E_000612"
     CDS             complement(12747..14078)
                     /locus_tag="ACL73E_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGS0800628.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14369..15193)
                     /gene="endA"
                     /locus_tag="ACL73E_000613"
     CDS             complement(14369..15193)
                     /gene="endA"
                     /locus_tag="ACL73E_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGS0800629.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15232..15420)
                     /locus_tag="ACL73E_000614"
     CDS             complement(15232..15420)
                     /locus_tag="ACL73E_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGS0800630.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15413..16696)
                     /gene="murA"
                     /locus_tag="ACL73E_000615"
     CDS             complement(15413..16696)
                     /gene="murA"
                     /locus_tag="ACL73E_000615"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS0800631.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16720..16950)
                     /locus_tag="ACL73E_000616"
     CDS             complement(16720..16950)
                     /locus_tag="ACL73E_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGS0800632.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17008..18045)
                     /locus_tag="ACL73E_000617"
     CDS             complement(17008..18045)
                     /locus_tag="ACL73E_000617"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGS0800633.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18029..18517)
                     /gene="coaD"
                     /locus_tag="ACL73E_000618"
     CDS             complement(18029..18517)
                     /gene="coaD"
                     /locus_tag="ACL73E_000618"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGS0800634.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(18507..19046)
                     /gene="rsmD"
                     /locus_tag="ACL73E_000619"
     CDS             complement(18507..19046)
                     /gene="rsmD"
                     /locus_tag="ACL73E_000619"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGS0800635.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19111..20103)
                     /gene="asnA"
                     /locus_tag="ACL73E_000620"
     CDS             complement(19111..20103)
                     /gene="asnA"
                     /locus_tag="ACL73E_000620"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGS0800636.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20214..20897)
                     /locus_tag="ACL73E_000621"
     CDS             complement(20214..20897)
                     /locus_tag="ACL73E_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HGS0800637.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(20953..21693)
                     /locus_tag="ACL73E_000622"
     CDS             complement(20953..21693)
                     /locus_tag="ACL73E_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGS0800638.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVATGILIFHLS"
     gene            21727..22005
                     /locus_tag="ACL73E_000623"
     CDS             21727..22005
                     /locus_tag="ACL73E_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGS0800639.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22083..23009
                     /gene="yidC"
                     /locus_tag="ACL73E_000624"
     CDS             22083..23009
                     /gene="yidC"
                     /locus_tag="ACL73E_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS0800640.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23084..23878)
                     /gene="pflA"
                     /locus_tag="ACL73E_000625"
     CDS             complement(23084..23878)
                     /gene="pflA"
                     /locus_tag="ACL73E_000625"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGS0800641.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(24004..25254)
                     /locus_tag="ACL73E_000626"
     CDS             complement(24004..25254)
                     /locus_tag="ACL73E_000626"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGS0800642.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTYLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25321..26148)
                     /gene="purR"
                     /locus_tag="ACL73E_000627"
     CDS             complement(25321..26148)
                     /gene="purR"
                     /locus_tag="ACL73E_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGS0800643.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26415..27356)
                     /locus_tag="ACL73E_000628"
     CDS             complement(26415..27356)
                     /locus_tag="ACL73E_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGS0800644.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(27346..28602)
                     /gene="rmuC"
                     /locus_tag="ACL73E_000629"
     CDS             complement(27346..28602)
                     /gene="rmuC"
                     /locus_tag="ACL73E_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGS0800645.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28604..29266)
                     /locus_tag="ACL73E_000630"
     CDS             complement(28604..29266)
                     /locus_tag="ACL73E_000630"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGS0800646.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29229..29885)
                     /gene="rpe"
                     /locus_tag="ACL73E_000631"
     CDS             complement(29229..29885)
                     /gene="rpe"
                     /locus_tag="ACL73E_000631"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGS0800647.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(29896..30774)
                     /gene="rsgA"
                     /locus_tag="ACL73E_000632"
     CDS             complement(29896..30774)
                     /gene="rsgA"
                     /locus_tag="ACL73E_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGS0800648.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(30776..31648)
                     /gene="rsmA"
                     /locus_tag="ACL73E_000633"
     CDS             complement(30776..31648)
                     /gene="rsmA"
                     /locus_tag="ACL73E_000633"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGS0800649.1"
                     /translation="MRIADYRVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(31779..32087)
                     /locus_tag="ACL73E_000634"
     CDS             complement(31779..32087)
                     /locus_tag="ACL73E_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800650.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32080..32721)
                     /locus_tag="ACL73E_000635"
     CDS             complement(32080..32721)
                     /locus_tag="ACL73E_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800651.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32723..34753)
                     /locus_tag="ACL73E_000636"
     CDS             complement(32723..34753)
                     /locus_tag="ACL73E_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGS0800652.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYIP
                     SGNVIYVSPRYLIEEKITVSSEFIDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(34830..35126)
                     /locus_tag="ACL73E_000637"
     CDS             complement(34830..35126)
                     /locus_tag="ACL73E_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS0800653.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(35446..36357)
                     /locus_tag="ACL73E_000638"
     CDS             complement(35446..36357)
                     /locus_tag="ACL73E_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGS0800654.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIASEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(36429..36989)
                     /gene="rnmV"
                     /locus_tag="ACL73E_000639"
     CDS             complement(36429..36989)
                     /gene="rnmV"
                     /locus_tag="ACL73E_000639"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGS0800655.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(36989..37762)
                     /locus_tag="ACL73E_000640"
     CDS             complement(36989..37762)
                     /locus_tag="ACL73E_000640"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGS0800656.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELLLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38067..38819)
                     /locus_tag="ACL73E_000641"
     CDS             complement(38067..38819)
                     /locus_tag="ACL73E_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HGS0800657.1"
                     /translation="MCPVIILFYYKVEVAGDGTATITFPDGSVVTILGKDTVQQSAKG
                     ESVTQEATPEYKLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASK
                     QLATEKESAKNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTM
                     EDVKEAETIGVQAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPN
                     TGSASSAALASLGLVVATSGFALLGRKTRRRK"
     gene            complement(38995..39129)
                     /gene="rpmH"
                     /locus_tag="ACL73E_000642"
     CDS             complement(38995..39129)
                     /gene="rpmH"
                     /locus_tag="ACL73E_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGS0800658.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(39274..40488)
                     /locus_tag="ACL73E_000643"
     CDS             complement(39274..40488)
                     /locus_tag="ACL73E_000643"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGS0800659.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKKLLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(40644..40937)
                     /locus_tag="ACL73E_000644"
     CDS             complement(40644..40937)
                     /locus_tag="ACL73E_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800660.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            41099..41551
                     /locus_tag="ACL73E_000645"
     CDS             41099..41551
                     /locus_tag="ACL73E_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGS0800661.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(41586..42974)
                     /locus_tag="ACL73E_000646"
     CDS             complement(41586..42974)
                     /locus_tag="ACL73E_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0800662.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            43040..44002
                     /locus_tag="ACL73E_000647"
     CDS             43040..44002
                     /locus_tag="ACL73E_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGS0800663.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(44298..45308)
                     /gene="ccpA"
                     /locus_tag="ACL73E_000648"
     CDS             complement(44298..45308)
                     /gene="ccpA"
                     /locus_tag="ACL73E_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGS0800664.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(45733..46332)
                     /locus_tag="ACL73E_000649"
     CDS             complement(45733..46332)
                     /locus_tag="ACL73E_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0800665.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDITILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(46334..47431)
                     /locus_tag="ACL73E_000650"
     CDS             complement(46334..47431)
                     /locus_tag="ACL73E_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0800666.1"
                     /translation="MLERLKSIHYMFCASLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTVFVAGNYIWFLFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     ERVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(47431..48168)
                     /locus_tag="ACL73E_000651"
     CDS             complement(47431..48168)
                     /locus_tag="ACL73E_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800667.1"
                     /translation="MKRWIALNKIEFLLTKRQLVYYLLSVGMPTAFYLFFSGIYQETP
                     GGPANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVEIPLGSWVGAAILLILGSVAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(48170..49054)
                     /locus_tag="ACL73E_000652"
     CDS             complement(48170..49054)
                     /locus_tag="ACL73E_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800668.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(49041..49235)
                     /locus_tag="ACL73E_000653"
     CDS             complement(49041..49235)
                     /locus_tag="ACL73E_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800669.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(49232..49438)
                     /locus_tag="ACL73E_000654"
     CDS             complement(49232..49438)
                     /locus_tag="ACL73E_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800670.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        14450 a        11373 c         9511 g        14686 t
ORIGIN      
        1 aaaagaaaag ggtttcacga atgaagaaaa atcgtggaat tcaaaaatta gctatattag
       61 tattactagg tgtttttatg tttagtaaca caattcctta ccaacagttt attcagaaga
      121 atagacaatt ggagattcga gtgcaatcac aaaagaagtc caatggtctt gatgttggga
      181 aggctgattg atttcgtatt actttaaaat tcaactattt agagaaaggt attctgatga
      241 gagcttgtaa caataccaga tagatataag aatggagatg tttgataaaa tgctttcata
      301 gctaaccaac tgttgaaaat tatgagttac aaaatctaaa gtatttaaga ttggtttata
      361 aaattaggtc tctgcctgta gaaaggaacg tgcagttaga aaggaggaaa aaataggata
      421 ctataattca gactgagatt tctaattaaa atatgtagtt gcatttcgct cattttcata
      481 atatttcatt cagaggagta ataatatgtt aaaatttaga tttgatgcgg gatggtaaag
      541 aataattgaa gaagattctt ttatcaatag tttagtaagc ttgttagttt atagagggca
      601 ggggtatttc tgccctctgt tttagaataa ggaatgcact atgaaaaaat tatttatact
      661 catatccaac ctgcttgcta gtttgttctt tgtttgggta tttaccattt ggactgatac
      721 atatgtctcc cattattacc ccaacgttgt tgtacgtgat tcttcccctg aaacaacttt
      781 tcagcatgtt gctacacgct tggaaaaact agcagaagaa acagatagct ttattgcgat
      841 tcaacaccaa gatcctaact cagaaggtac tacagttttt tcttatacga cctttgggga
      901 cggaaagttg cctgatgggc ttcaggaaaa aaatctagaa gatgctcaaa gtagtagtgt
      961 tgaaacaaac tattttgtat tcgatggaca cctagatatt cacttgctaa gggaagagct
     1021 aagtcaactt ggcttgacta acatgcacct gacaattcca tctaaactat ctacgttaat
     1081 ggctatcttt agtaacggat ttcagttaat cagtctattg attttcatct taacctttgt
     1141 agcactgact ttaattagtc aaattagcca attacggtca tcgggcattc gcctcatttc
     1201 aggagagaaa cggtggtcca ttttccttag accagttggt gaggatttga aagcgatagc
     1261 tgttggtttc agtttagctg gcgtgctcgc cattcttatg caaaaaattc tgtcgcttcc
     1321 aacgcaatcc ctaatgacca caggagaagg cttgctcagt tataatctca tcttgttgtc
     1381 gatctccctg tttttcactc aactcttcgc agttgggata aaaaagatac acctgatgca
     1441 gattataaaa gggcaagtgc ctgtcagagg aatcattagt ttgattttaa tcggtcaact
     1501 attagcgatt attattgtaa cgctgggaat agggagtagc ttaaagtatt cccaagcctg
     1561 gcaacagcat cggattggac aagaggtttg gagtcaggaa aggcaactga ttaccctatc
     1621 aatcagccgt gaaggaacga gtcctggttt tgatgaacaa gctcaaagga aactcagaac
     1681 ttggtatcaa ttgatggatc tggctgtttc agaacaaaag gctttcttat ctagacacca
     1741 gttaattgac cgtactttgc aaaatggcat ggcttcctcc aaaaacttga taacctctac
     1801 agaatggcac gattacaacc cgaatggcaa tgtccttatc gtcacaccgc aatacttgga
     1861 gcgtcaaaac attcctgtag atacaactat tgagcaaaag atgaatcacc ttgatgtagg
     1921 ggagtttgtc ttattgctgc ctgaacacct ccgttcagag gaagaacatt ataaatctgt
     1981 ttttgaagac gacttaacca gtcgcatgtc tagtcaagat gaacgacagc aaatgactgc
     2041 tacggtaggt tatttagaat caggtcagga tcgttttgtg tataatacga cccctatttc
     2101 ttaccagcag tttttgaaag atccaatcat cattgttata acaccccaat caactggtcc
     2161 acagtccatt ttgttttgga tagacgcagt acagaactac gttctcttta atcaattgtc
     2221 tgatgcccag gagcttatcc agagacaagg cattgaaaat tgggtctcag aaatgcaaac
     2281 aggttaccac aactacatca cattattgga taatatccag agggaacgtt gggtaatgct
     2341 agcaggagct gtgcttggga ttgcaacttc aatcttgttg tttaacacta tgaataggct
     2401 ctactttgaa gaatttagac gtgccatttt tatcaaacgc attgcaggtc tcaggttctt
     2461 agaaatccat cgcacttatc tctttgctca actgggtgtg tttttactgg gatttgttgc
     2521 gagtgtattt cttcaggtag agataggagt tgctttctta gtcttgttac tctttactgg
     2581 tctatctctt ttacagttac atgtccaaat gcagaaagaa aacaagatgt ccattcttgt
     2641 tttgaaggga ggttaatatg attgaactta aacaggtgag taaatctttt ggagaacgag
     2701 agttattttc gaatctttca atgacatttg aggctggaaa agtctatgcc ttaattggtt
     2761 caagtggtag cggaaaaaca accttgatga acatgattgg gaaattagaa ccttatgatg
     2821 ggacgatttt ttaccgaggt aaagacttgg ccaattataa atcgagtgat tttttccgtc
     2881 acgaattggg ctacctcttc cagaactttg gcttaattga aaaccaaagt attgaagaaa
     2941 accttaagct aggtctcatt ggtcaaaagt tgagtcggtc ggaacagcgg ttgaggcaga
     3001 agcaggcttt agaacaggtc ggcctggctt atcttgacct agataagcgc atctttgagt
     3061 tatcgggcgg agaatcgcaa cgggttgcct tggcaaaaat tatcttaaag aatccaccct
     3121 ttattctggc agatgagcca acagcttcaa tagacccagc aacctctcag ttgattatgg
     3181 agattttgct atctcttcga gatgataata ggctaatcat tatcgcaaca cataatccgg
     3241 caatttggga gatggctgat gaagtgttca cgatggatca tctgaaataa aaatccttgt
     3301 ttttaattgc acgatgagtt actgaaatat tatcatgaat caagaattgg agttaattta
     3361 gaattgtact ttattaatat tgaggtaact ttttcttgat aaaggaagaa ataatggaga
     3421 ggaagttaga atgaaaaaat tcgacaatta tattattgag aagccttgcg attctaattc
     3481 agataaactg caaaaaatct taataattga aagtttggta gatgatattt tgcaattttc
     3541 tctcagaatc aataatagtg taggagagat tttcctccta caaccgtttt aaaagaaaac
     3601 tatctttatt ccatgttatt ttgaggaaga tattgtgaaa gtcaaagatg atgataaagt
     3661 tgagtggaat ttgttagaat ttcaaaaatt tagagcattt ttggcttagt aatctgtgtt
     3721 gaaggctcaa aacctatggt aaaaaagtcg ctttgaaaac gtattgcctc caaagattta
     3781 gttaaataat gatttaacac aaaaagaaat tattgaagtt ctggaaagat gttgtttcag
     3841 tattgagaaa aggtgggaaa aacttgcgat tttcacagag aaaggaagaa aaagtataga
     3901 aatatagtca attgaaacaa gaacaggata aaagaacctt ttgtgccata tttttctcct
     3961 ttcgctttac aattggcttg aacaccttta ttgtatcgcg tttggagttt ttttggtata
     4021 accttcgacg cgcacccgca tagcgggtgt ttttttgtct cgcacctaac ggagcgagac
     4081 gaactaatag tcacttaatc aaaaaacgca ccatatcaaa aactaaaaag tttgatatca
     4141 tgcgtcatgt cttaaactaa ttgactatac tttctattca aatgagcttt taaccaattg
     4201 attgagccaa tccactctta aaaccaaaga gcaatttctc gcttagctga ctcttctgaa
     4261 tctgaaccat gtacaacatt ttggataacc tcattttctc cagcagcttt tgcaaagtca
     4321 cctcgaatag tgcctggtaa agcttcttct ggacgagttg cacccatcat ggtccgccaa
     4381 gtttcgatta ctttgggacc agaaatgaca cccacaagaa ctggacctga agtcatgaat
     4441 tcacgaatcg gtaggtaaaa actctgacca accaagtcct gatagtgctg gtcaatcaac
     4501 tcttctgaaa cctgtgaacg aaactccaat ttttcgattg taaatccacg ttgttcgatg
     4561 cgctttaaca cttcacccac tagccctctt tttacaccat ctggtttgat gataaagaat
     4621 gtttgttcca tacccgtctc ctttgtcagc ttctttcttt tattttacca catttcgtgg
     4681 aaaaatggag aaagttttca gaagagagaa tgagagaacc cgagggttct ctcattctct
     4741 cttattctac tgtttcttcc acagtttcaa cggcagtatc cacaactact tctgttgttt
     4801 cttcatttcc ttcttcctct actggaggat taaggtattc ttcttcgttg acagcatgtg
     4861 gttcaaggtt acggtaacgg gccataccag taccagctgg gatgatctta ccgatgataa
     4921 cattttcttt aagtccaagg agatggtctt tcttaccacg gatagctgcg tcagtaagga
     4981 cacgagttgt ttcttggaag gaagctgctg acaagaaact gtttgtttca agtgaggctt
     5041 tggtaattcc cataaggact gggcgacctg tcgctggaac tccacctgcg ataaggacat
     5101 ctttgttggc atctgtaaag tcattgatat ccatgagggt acccatgaga agatctgtat
     5161 cacctggatc catgacacgg actttacgga tcatttgacg aaccattacc tcgatgtgtt
     5221 tgtcaccgat ttctacccct tggctacggt aaactttttg tacttcaccg agaaggtacg
     5281 tttcaactga caagacatca cgaactgcaa ggagacgttt tggttggata gaaccttctg
     5341 tcagagcagc accacgcgct acttggcccc caacttcgac acgcatacga gctgtaaatg
     5401 gaacgacata ttcaccttcg ccagtttcac ccttaacaaa gactttcttg gtacgagttg
     5461 atgcatcttc ttcgatagca gtaacttgtc ctttaacctc tgtgataacc gcttcccctt
     5521 taggattacg ggcttcaaag atttcttgga cacgaggaag accctgagtg atatcggtat
     5581 ttgaggcaac cccacctgtg tggaaggtac gcattgtaag ctgtgtacca ggttccccga
     5641 tagattgggc agcaattgta ccaactgctt caccaacttc aaccgcatca ccagtcgcca
     5701 agtttatacc gtaacagtga cggcagacac cgtgacgagt gttacatgta aatacagaac
     5761 ggatagtcac ttcttccaca ccagcattga caatttcacg cgccttgtct tctgtaatca
     5821 attcatttgg accaataatc actgcaccag tttctggatg tttaacagtt ttcttagtgt
     5881 aacgaccgtt gagacgctct tcgagagact cgatcatctc ttttccttct gcgatagaac
     5941 ggatcaagag accacggtca gttccacagt cgtcctcacg gatgataacg tcttgggcaa
     6001 cgtcgaccaa acgacgagtc aagtaacctg agtcggctgt cttaagggcc gtatcggtca
     6061 tacctttacg agcaccgtga gttgagaaga acatttccaa taccgacaaa ccttcgcgga
     6121 agtttgaaag gattggcaat tccatgatac gtccattcgg agcagccatc agaccacgca
     6181 taccggcaag ctgtgagaag tttgagatgt taccacgggc tccagagtcc atcatcataa
     6241 cgattgggtt cttaggatct tggttagcaa tcaagcgttt ctcaagtttt tcacgggcag
     6301 cacgccattc agctgtaaca gcattgtaac gctcgtcgtc tgtgatcata ccacgacgga
     6361 attgtttggt gatttgctcg acacgtttgt gtgattcttc aatgatttca gccttgtcat
     6421 caacgactgg gatatcggca atacccactg tcaatcctgc aagagttgag tggtggtaac
     6481 cgagattctt catgcggtca agtagggcag aagtttctgt cgtacggaaa cgtttgaaga
     6541 tttcagcgat gatatttccg aggtttttct tcttgaatgg agggttgagc tcaagattgc
     6601 tgatagcttc cttgatatct ccaccaagtg gcaagaagta tttagctgga acaccttctg
     6661 tcaagttggc attgtttggt tcttgcaagt atggtagccc ctctggcatg atatcgttga
     6721 agagaatttt accaactgtt gtaagcaaga ccttatgtct ttgctcttct gtccaaggct
     6781 tgttgaggct gtctgttgcg ataccaacac gtgagtggag gtgaacataa ccattgcggt
     6841 aagccataac cgcttcgtca cggtctttga agaccattcc ttcaccttcg cgaccagctt
     6901 cttccatggt caagtagtag ttacccaaaa ccatgtcctg agatggagta actaccggtt
     6961 tcccatcttt cggattcaag atgtgctcag cagctagcat gaggatacga gcttctgctt
     7021 gtgcttcttc tgaaagtggt acgtggatgg ccatttggtc cccgtcaaag tcagcattgt
     7081 aggcttcaca gacaagtggg tgcaagcgaa gagccttacc atcaatcaag actggctcga
     7141 aggcttggat acccaaacgg tgaagggtcg gtgcgcggtt caaaagcact gggtgttctt
     7201 taatcacttc ttcaaggata tcccagatac gctcatctcc gcgttccacc aagcgtttag
     7261 ctgctttgac gttttgcacg atatcacggg caacgatttc acgcatgaca aatggtttaa
     7321 agagttcaat cgccatttca cgtggcacac cacattggta catcttaaga gttggaccaa
     7381 cggcgataac ggaacgtcct gagaagtcaa cacgtttacc gagcaagttt tgacggaagc
     7441 gtccttgttt acctttaagc atgtggctca atgatttcaa tggacggcta cctggtcctg
     7501 tgattggacg accacgacga ccattgtcaa tcaaagcgtc aactgcttct tgaagcatac
     7561 gcttctcatt ttgaacgatg atacctggtg catttaactc aagcaaacga gccaaacggt
     7621 tgttacggtt gataacacgg cggtaaaggt cattcaagtc agatgaggca aaacggccac
     7681 catccaactg caacattgga cgaagatctg gtgggataac cggaagaatg ttaagaatca
     7741 tccattcagg tttgtttcca gacttgtaaa aggcatccaa aacatccaaa cgacggatgg
     7801 ctttgacacg tttttgtcca gtagctgttt tcaattcttc tttgagttca gcaatttctt
     7861 tttcaagatc tacttgcttc aaaaggtctt ggatggcttc cgcacccatc ttggcaacaa
     7921 atgaaccata accatattca cgcaagcgct ctcggtattc gcgctctgtc atgatagact
     7981 tgtgctcaag tggtgtatcc ttaggatcaa tcaccacata agccgcaaag tagataactt
     8041 cctcgagggc acgagggctc atatcaaggg tcaagcccat acggcttgga atccccttga
     8101 agtaccagat gtgagataca ggagctttca attcgatatg tcccatacgc tcacgacgaa
     8161 ctttcgtacg cgttacttca accccacagc ggtcacaaac aattcctctg taacgaatgc
     8221 gtttgtactt accacaagca cattcccagt cttttgtagg accaaagatc acttcatcaa
     8281 agagtccttc acgttctggt ttcaaggtac gataattgat tgtttcaggt tttttgactt
     8341 ctccataaga ccatgaacgg actttacttg gagaagctag ggtgatttgc atacttttaa
     8401 aacgatttac atcaaccact atttcttccc tttctattct aagtgaactg cttattcttg
     8461 ttcagcagct tcttctgttg cttccgcttt tgttgctttc tcagcttctt cagcttcaaa
     8521 ggctgcttta gcctcttgag ctgctttttc gcgggctttt tcaaggtcat ctacgtggat
     8581 gacatcttcg tccattcctt catccaagtc gcgaagttcc acttcttggt catcttcgtc
     8641 taggacacgc atgtcaagac caagagattg caattctttg acaagaactc ggaaggattc
     8701 tggaacacct ggttttggaa ttggtttgcc ttttgtaata gcttcatagg ctttcaaacg
     8761 tccgttgata tcgtccgact tgtaagtcaa gatttcttga aggacatttg acgcaccgta
     8821 ggcttcaaga gcccaaacct ccatctcacc gaaacgttgt ccaccaaact gagctttacc
     8881 tccgagtggt tgttgggtaa cagttgagta aggtccgact gaacgcgcat gcaatttatc
     8941 gtcaaccatg tggtggagtt tgatcatgta catgactcca acagaaacac ggttatcaaa
     9001 tggttcacct gtacgtccat cgtaaaggat tgtcttggca tcgctatcca tacctgcttc
     9061 tttaacagtt gaccaaagat cttcagaact tgctccatca aagactggtg tcgcaatgtg
     9121 aataccaaga gtacgagctg ccataccaag gtgaagctcc ataacctgac cgatattcat
     9181 acgtgatggc accccaagtg ggttcaacat gatgtcgact ggagttccgt ctggaaggta
     9241 aggcatgtct tctacaggaa cgatacgaga gacaacccct ttgtttccgt gacgtccggc
     9301 cattttatct ccgaccttaa tcttacgttt ttgagcgatg taaacacgaa ccaacatgtt
     9361 aacacctgat tgcaactcat ctccatttac acgtgtaaag atcttaacat cacgaacgac
     9421 accatcggca ccgtgtggta cacgaagaga agtatcacgc acttcacgag acttgtctcc
     9481 aaagatagcg tgcaagagac gttcttcagc tgaaagatct ttctcaccct taggtgttac
     9541 tttacctaca agaatatcac cttctttaac ctcagcacca atacggataa tccccatttc
     9601 gtcaaggtct ttgagggcat cttcaccaac gtttggaatt tcgcgagtga tttcttcagg
     9661 cccaagcttt gtatcgcgcg tttctgattc gtattcttca aggtgaacag atgtgtagac
     9721 atcgtccttc accaagcgtt cgctcatgat aacggcatcc tcgaagttgt aaccttccca
     9781 agtcatgtag gcaacgattg ggttttgtcc aagcgccatt tctccatttt ccatagaagg
     9841 tccgtcagcg atgaaatcgc ctttttcaac gacatcacca acttttacga gagtgcgttg
     9901 gttgtaagca gtacctgagt ttgaacgacg gaatttttgg atgtggtaaa catccaatga
     9961 accatcttca cgacgaactt ctaccttgtc agcatctgcg taagtaactt taccatcata
    10021 ctgagcaatc acagccgcac cagaatcgtg ggctgcttgg tattccatac cagtaccaac
    10081 gtaaggtgcc tgaggattaa tcaatggcac agcctgacgt tgcatattgg ctcccatgag
    10141 ggcacggttg gagtcatcgt tttccaagaa aggaatacat gctgtcgcaa cggcaactac
    10201 ctgttttggt gaaacgtcca tgtagtcaac aatattagct ggatactctt ggttgacccc
    10261 ttggtgacgt cccatgacaa tcttctcagc aaaggttcca tcttcattca gactagagtt
    10321 agcctgagct acagtatatt catcttcttc atcagctgtc aaccaaacaa tttcgttcgt
    10381 gacaacacct gtttcacggt caaccttacg gtatggtgtt tgaacaaaac catatttgtt
    10441 caagtgtccg taagatgaca agttattgat caaaccgatg ttaggtcctt caggtgtctc
    10501 gattggacac atacgaccat agtgagtgta gtgcacgtca cgtacttcat atccagcacg
    10561 gtcacgagtc aaaccaccag gtcctaaggc tgacaaacgg cgtttgtgag acaactcaga
    10621 aagcgggttg tgttggtcca tgaactgtga caactgtgat gaaccaaaga attctttaac
    10681 tgcagctgtt acaggacgga tattgataat ttgttgtggt gtcaagactt cattgtcctg
    10741 aacagacata cgttcacgga cattacgttc catacgagaa agtcccaaac gtacttggtt
    10801 ggcaagcaat tcaccaaccg cacggatacg acgatttcca aggtggtcga tatcatctac
    10861 acggccaagt ccttcagcca agttgaggaa gtagctcatc tcagcaagga tatctgcagg
    10921 agtcaccgta cgaaccttgt catctgggtt agcattacca atgatcgtta cgacgcgatc
    10981 tggatcagtt ggagcaataa ccttgaattt ttgaagaaca acaggctcag tcacaacggc
    11041 tgcatcgttt gggatgtaga caatcttgtt caagtcgcca tccaaatggc tttcaatgct
    11101 ttcaatcacg ctacgagtca taatcgtacc agcttctacc aagatttctc cagtttcagg
    11161 gtctaccaat ggctctgcaa tggtttggtt gagcaaacgt gttttaacat tgagtttttt
    11221 attgattttg taacgaccaa ctgctgccaa gtcatagcga cgtgggtcaa agaagcgagc
    11281 cacaagcaag ctacgtgagc tttcagccgt cttaggctca cctggacgaa ggcgttcgta
    11341 aatttctttc aaggcttcgt ctgtacgaga gtccattgga ttcttgtgga tatctttttc
    11401 aacagtgttg cgaaccaatt cgctgtcacc aaaaatatca aagatttcat catcacctga
    11461 gaaaccaaga gcacgaacca aggttgtaaa tggaatctta cgagtacggt cgatacgagt
    11521 gtaggtgata tcttttgagt cgctttcaag ttccaaccaa gctccacggt tagggataac
    11581 agttgaacca tagcccacct taccattttt gtctactttg tcgttaaagt aaacacctgg
    11641 tgagcggacc aactgagaaa cgataatacg ttcaccacca ttgatgatga aagtacccat
    11701 ttctgtcatg attgggaaat caccaaagaa aacttcttgg gtcttgattt cgcctgtttc
    11761 tttattgatc aagcggaagg ttacaaaaat tggtgctgag tagctagcat cgtgaatacg
    11821 agcttcttct agcgtgtatt ttggttcctt gatttcatat ccaacaaatt ccaactccat
    11881 tgtgtctgtg aagtttgaaa ttggcaatac atcttcaaac acttccttaa gaccgtggtc
    11941 taggaaagct ttgaatgagt cagtttgaat ttcaatcaaa tttggtaagt caagaacttc
    12001 tttgattctt gaaaaactac gacgggtacg atgtttcccg tattgaacgt catgtcctgc
    12061 caagatgatt ctcctttgta aataagttcc aagccttgtc aatcaggctt ttctaatcgc
    12121 catatggttg taaacccctt atcaccgtgt cctcttgacg aattttcaga atctttaagc
    12181 ctctgttaca aatgctcaaa atcttgaaaa aaagcacaaa aagagcagct aaatctgact
    12241 ttttcagaag atttaactgc tgtgagcctt gtctggacaa tatttcagac aaaacctacg
    12301 acaaatgatt acccatatta taccctattt agctagattt ttcaagggga ttcagtaggt
    12361 ttttggtaat ttttttccca tagaaaactt ggcatcacat tcgaatcacg ctatggtaca
    12421 aaaaactgaa aaaactattg actgaaaatc attttcaagg tataataata aacgttaagg
    12481 cggtatagcc aagtggtaag gcacggctct gcaaaagctt gatcgtcggt tcaaatccgt
    12541 ctaccgcctt ctataacttg atttatcagg tttcaaatga acagaaagcc caatttgaag
    12601 ggcttttttt attttccctc gaataaatac gtataacttt aaaaactttt ggagcgagtt
    12661 tgtggcagag ttctttccat ggcataattc ccttttgaaa tcaattgaaa aaagcttcgt
    12721 cacgcctggt gacaaaagcc tctagtttat tctgtttctt cttctatttc gacttctgtg
    12781 atttggactt ttaccttggt aacacgtcca ttcttcactt tatcattggt taagataaac
    12841 tgtttgtttt ggctgaccaa ttcatagctg agtttctcag tcgttggaat ggttcccact
    12901 cctgtcaaat aataaccagc gatggtatca acgtcatcac tttccagttc aacatcaaag
    12961 taattattga aatcattgag ggtcatagtt ccttgaacaa tgtaggtatc ctcgccaatc
    13021 tgatgaacat ctattgctgc tttatccgtt tcatcatcaa tttcaccaac aatttcctct
    13081 aagaggtctt ccaaagtcac taaaccagcc ataccaccgt attcatccag caagattgcc
    13141 atttgtcttt gggtatttcg cagttctttt agcaagtcat ccacaaaaat agtttcaggt
    13201 acaaaaagtg gatcttgtaa aattctcttc caaacaatat tgtcaaaacc gtccacaaag
    13261 cctgccttaa ggagactctt ggtgtgaatg attccaatta cattgtcctt atccccatca
    13321 taaaccggga tacgagaata attttgtttt aaaatacttt ggataatggc ttgactatca
    13381 tcctgaatat ccaccataaa ggcatccgtt cgaggaacca taacctctcg tgccatcagt
    13441 tcatcgagcg aaaagacacc ttgtagcatc tcaatctcat cagcatccaa tgtttcttca
    13501 ctatttgtca gcatataggc aatttcatca cgggtcatct tttcatccgc atcatcgaat
    13561 gacataggag tcaaatggct caagaaattg gtcgaagcag ctaaaagcca aacaaaagga
    13621 ctgactagtt ttccgatccc aatgataacc ggcgctgtac gaattgccaa ggcatccttt
    13681 agattaagag cgattctctt aggatataat tccccaaaaa cgatggaaat ataggtcaaa
    13741 aatgccaagg atagaaaagt tgccacggct tgtgctgttt cgccattccc aagccaagag
    13801 gcaatcacac gtcctagagt atcagttaaa ctcgcccctg ataagattgt aatcagggtg
    13861 attcctacct gaatggttga taaaaagtgg ttaggatttt ctagtacctt cagcaggcga
    13921 atgtagcgtc tgtctccttc ttccgccttt tgttcaactc gggcacgatt aagagaaacc
    13981 atggccattt ctgtggctga gaaaaaggca tttaataccg tcaagataaa caataaaaca
    14041 aattgtagca acaaattctg actacttggg tcttccatag ttcttctcct aaaatagtat
    14101 cttatccttt attatatcac aaaatttaat ccaatacata ttattttttt cttagcgtaa
    14161 cttccatctc tctcccaaaa ctggaagtta gtctaagacg gatttccact gatttcacgc
    14221 gtttttctca tactaaaagc taggttgtgg gaaactggaa gttagtttta gaagttacta
    14281 ttttttctta gtacctgttc tagccctgct taaactagta aaaagaactc ctacatccat
    14341 aagtgacata ggagtttagg cttatctttt actgagttac agttacttct ccagttcggt
    14401 aatccagttg aagtcccttt tgaacattgg gaactagaac attgaattcc aattctccat
    14461 ccgaagactt ggcttcaatc tgtgaagctg agggaactaa atcctcgttt gaagcgtagt
    14521 aaagggttac acggtaacgg acacgcttgt tttggtccaa ggctttacgc accttgcttt
    14581 catagtagtt ttgaccagtc gaatactcgg cttgtgcctg atttgcccag gctgtctgaa
    14641 cagcaatgtt tttaggattg cttgttgagg catcaaaacc atccaaacca ccgattaagg
    14701 catagcctaa caaatgacct ctatcgactg catgggtata agagcccttt agattcttga
    14761 cctgatgcca acctggagga gtccaagaag ttgaaccatt cccagtttct ttacgattct
    14821 tgtactgacg agtggcctta gacaagaggg cattagctac ggttggaaca gtttccttgc
    14881 ccactgtctt tgttttattg tcagcgtagg gcttacttga aaccttggca tctagatttg
    14941 ttttattacc attgacgata aaagcacctg agccattcca ctccagactc ccctttattt
    15001 gactcttgac tgcgtctgtt aagacactct ctgccaatgc ttgactagga gcttcaggcg
    15061 cttgtttttt ctgactaagc ttggttttag gactattagg tgccgactgc atctgcttga
    15121 tataatagct ccctgtagac aaaagcaata acactagcag tccgattagt gtctgtcttg
    15181 tttttttgtt catatttctc cttatcttta gaaaaaggct ggttctccag cctaatttcc
    15241 tgtaaattta tgaatcaatt cctgccattt tgctggagac aggatagccc atggatcttg
    15301 acccttgccc aagattccat aacctaccat taaaccgatt cctagagcca gagtacctaa
    15361 aatcagtact atgatgacta aaagtaaacg cttgactacg tagcttgatt tcttattcat
    15421 cttcatcact tgcctcaatc cgctgaatct tagcacctag ctgcgccaac ttctcatgga
    15481 aaccgtagta acctctatcc aagtgaacca atttaccgac cacagtttct ccctgtgcta
    15541 ccaaacctgt caaaatcaag gctgcactgg cacgaaggtc agttgaaaga acttctgctc
    15601 cctgcaaagg ctgtccacca acaatacgag ctgtatcacg gataatctca gaatgcaagc
    15661 ccatgcggcg catctcttct aggtgttgga aacgattttc gaaaactgtc tccaccatgg
    15721 ttgattcgcc ttttgcaact gtcatcaagg ctgtaaattg agcctgcata tctgttggaa
    15781 atcctgggtg gggcaaggtt ttcacatgaa cagcttttag attttctagt tgagaacgaa
    15841 cacgaattcc ttcgtcttct tcaattactt caacacccat ttcaagtaac ttggcaatca
    15901 agggacggtt gtgctcccag acagcgtctc gaatcaagac atcaccacca gtcatggcag
    15961 cagctaccat aaaggttcct gcttcgatac ggtcttggac tacattgtga gtcgtaccat
    16021 gaagtttctc aacaccagta atggttatag tctctgtacc agcacctttg accttggctc
    16081 ccatttcatt aaggagaatg gctaagtcaa caatctcagg ctcacgcgca gcattctcaa
    16141 tcactgtcac cccatcagcc agagtcgctg ccatcatcaa gttctgcgtt gcaccaacac
    16201 ttggaaagtc catatagata tgagcgccat gcaagcgttc tgccttggct tcgatgtaac
    16261 cagctgtctg actaatctta acccccatag cttccagacc tttcaaatga agatcaatag
    16321 gacggctacc aatcgtacaa ccacctggca tggatacctt ggcatgaccc acacgggcaa
    16381 ggattggccc taatacaacg atggaggcgc gcatcttgct gacatacttg taaggggctt
    16441 cctcagtgat gtcgccagta gcatccacct tgacaagatg agcttcctca tcaaagtcaa
    16501 ccttggcatt caaaccacca actacctgat tcataataaa gacatccgac aaaatcggaa
    16561 cattctgcaa gacggtcttt ccttcacttg ctagaatagt cgctgccaac aagggtaaga
    16621 ctgcattttt tgctccctcg atcgtcacgc ttcctaccag acgattatcg ccaccttgaa
    16681 ccacaatttt atccatactc gtttccttta ctcttgattt cataataatc ctctaagcgc
    16741 ttcttgccac aaatgataca ggctaataaa gaaagaactc aggatgtagc ctatgacaat
    16801 gctaaaaaag gctactaata aacgaacttt tcttgtatta tcatctgtca cttttaaaac
    16861 cttctcccat ctaacaagat cctttaaaag gtaaaaactc acataaataa agaacatatg
    16921 actacttaga gtgaataata attgaaccat ttgactatta taccatcttc tctgtttgtg
    16981 cgctagtttg gaaacttcac tcaaaaatta gggattgttt ttcaagtaat caatcgcatc
    17041 ttgtagggtt ttaacgggca cgattttcat atccgtcttg attgttttag ccgcttctag
    17101 ggctgtttgg tagttgtttt tcgcgtccgg atgcgccttt tgttcttctt cgctaacagg
    17161 gttatcagga gcaaagaaaa tagcagcacc tgccctagcc gaagctacaa ccttcttatc
    17221 aatacctcca atgtctccca cattaccatc gcggtcaatg gtacctgtac cggcaacaat
    17281 acgaccatta cgaagatctg ggtgagctat ttgagtatag atagctagac taaacatgag
    17341 accagcactt ggaccgccaa taccagctgt tgaaaagcta attgggacat tgctgattac
    17401 ctctgtacgg tcaatcaagc cgattccaat tccatttttg ccattttcca aggtgatgat
    17461 ttttccttct gcagacttgg tttgcccatc ctcttcatag gtgaccttga cggaatcccc
    17521 taatttttga gaactgacgt aatcaatcaa gtctttggaa ctatcaaagg tctgatcatt
    17581 gactgctgtg actgtatcag agatattgag aatcccttta aaggttgaat tatccgtcac
    17641 attcaaaaca taaactccaa agtacttgag ttcgatatcc ttaccagctg tttttagtcc
    17701 ttgatacttg gccatatttt gcgatgtttg catgtagaat tgattgattc gcataaattc
    17761 aacatcggaa gaaccacctg tagtctcctg agcactacga atatctgtaa aaggtgtcaa
    17821 ccaagcataa atcatatgag ctaaagtggc atgttgaaca ccaaccgtaa cgaattgata
    17881 ggcaccagct tccttatctt ctgtgtcatt tactttaagg acttggcgaa tatcttccga
    17941 accacctgga acctctatat aataaggcaa gggcactaca aatgccaaga aagtcacaat
    18001 caaggccgca atgacgtata agggccatct aatctttttt ttcatttctt atttcctcca
    18061 aaatactctc gggaacatag caggcaatat cctgaccaaa cttcaaaagc tctctaacgc
    18121 ctgatgaact gatatagaga tgttcaggtc gactatgtaa ataaatagtc tctatatcag
    18181 aagacagctg atgattgtag taatcaaaac tggcttcata ttgcaaatcc gacgcatttc
    18241 tcaagcctcg cactaggcaa gtagccccca gtctttttgc gacatcgacc accaatttat
    18301 catgagaaga cacgacttta acatttccca aatgtttcac agccttttct aacccccgtt
    18361 tacgattttc aagagggaga aatccttgtt tgtggggatt aaaaaaaata cccacataaa
    18421 gcttatcaaa gagtctgctc gcccgttcaa tcatatccag atgcccattt gtcatcggat
    18481 caaatgagcc tgtgaataag ccaatcttat ctgacataga ctgtcacctt actaattcca
    18541 taaatctttt ccttccagat acccagacag gcaatctctt ctggaagttc aacggcctta
    18601 tccgtctcgc acacaaccat aacatcttca gaaaaaagct ctctctcagc cattttttca
    18661 atatctgcta cgatttgttc cttggcatag ggagggtcta agaaaacgag gtcaaattcc
    18721 ccagatacct gttccaatgc cctctctgca tccatcttga ggagttgaaa ttttccaact
    18781 tccttggtca tctggatatt ttcagccacg atggtctgag ccttacggtc tcgctccacc
    18841 aaaacagcac tggacatgcc acgcgatact gcttcgatag ataaaccacc actacctgca
    18901 taaaggtcca agactcgtcc cccttcaaag tagggaccaa tcatgttaaa aatggctccc
    18961 ctaaccttat ccgaagtagg tcttgtcgtc ttgccttcta gtgtcttgag gggacgtccc
    19021 ccatagattc ctgatacgat tttcatactg tttattatac caaattatag acaaaaagag
    19081 aaagaaaacc gaaccttgcg gttcgattct ctacaaaata ttttcgtaag tatcgcggac
    19141 ttcttgaggc caaacacttg tttgcacttc tccgatgtgt ctcttgcgaa gtaggaacat
    19201 ggccatacga gattgtccaa ttcctccacc gattgtcaat gggaatagac cattcaacaa
    19261 agacttgtgc cattccaatt ccaagcggtc ttcatcacct gtaatttcca cctgacgtct
    19321 aagagtttct tcatctacac gaattcccat agaagacaac tcaaaggctc cacctaaaga
    19381 ctcattccag acaagaatat caccatttag acccttgtag ccattctcag actcgcttgt
    19441 ccagtcatca tagtctggtg cacgtccatc gtgcggttta ccatctggca actcgccacc
    19501 gataccaatc aaaaagacgg ctccaaattc tttacaaatc gcattttcac gttctttcgg
    19561 tgtcaagtct gggtagcgtt ctaccaattc ttctgtatgg ataaaggtga tttgttttgg
    19621 caagatagac tcgatgtcat agcgggcttc aacagctagc tcagtcaggc gaatagcctt
    19681 ataaatcttc tcaactgttt cttttagata aacgatgtta cgcttaccat ttgggataac
    19741 cttctcccag tcccactggt caacataaac agagtgggtt gcatccaagg aatcctcatc
    19801 tggacgaagg gctttcatgt ggacaaagag accctctcct tcaccaaagc caaaacgagc
    19861 caaggtgtgg cgtttccatt tagcaagtga gtgcaccact tcataagtag catcagggat
    19921 ttggagaacc ttgaccgata ctggattttc cacaccagac aggttgtcct gcattccgtc
    19981 accgacctta ctcaagatag gaccttgaac ttcgacaact tctagcttat ctttcaaata
    20041 ctgggtaaaa gtgtttttga caaaggaaat ttcttcttgt tgatggataa aacttttctt
    20101 catagacaac tcctcaaaaa tttaataaac gtattataca cctatttcca agaaaagaaa
    20161 agagaaaatt taaaaaaatc agtgtcactc aaaacactga tttcatagac cttttagtca
    20221 ttgcgaccaa agatacgtag aatacttagg aaaagattga taaaatcaag atagatgctg
    20281 agagccattg acaccaccca gcctgtcgct acacgacctt gtgattgttc ataggcgagg
    20341 cgaatctttt ggttatccca agcaatcaac cctgaaaaaa ccaaaaccat ggctacgcta
    20401 atcatataat caaagaagcc actagccaag aaaatattga ctaccatagc aatcagtaaa
    20461 ccaatgagag ctgccatcat tgctcgacca atcccactca agtctttctt ggtaaagata
    20521 ccaactgccg ccatgacaaa gaagagaagg gcgctcgata caaaggcaga taaaactgta
    20581 cccggagtat agaaagccac cacaaaacta agggtaaagc cgtttaaaac ggagtaaagt
    20641 aaaaatactg gaagagcagc tggactattt cttgaagcca tgctactggc aacgaaaacc
    20701 aaagccaact ccgcaaaagt agcaatggtc aaccagagac gcccctgcat caacaagtaa
    20761 accaactgag actgaaagac cgtcaacata aggcctgata ccaaagcaga tagtccgatt
    20821 cccagaccaa caaaggcata aaccttagcg taaaattgat tgagacctgc acggtcatgt
    20881 ataatagtgt gattcatcct tttctccttt tctgtgaaca tctttccttg attataacaa
    20941 aaaaagttaa aattagctta aatggaagat taaaataccg gttgcaactg caacattcaa
    21001 actctcggcc tgccccttca tgctaatatg gaccaactgg tctgcacttt cagccataag
    21061 gggactaatt ccttgaccct catttcccat aactagtaca aaattttcta tagaaggcag
    21121 ttctctgtaa tcaacagaat ctttagatag ggttgttgct agcactggga tagctacctt
    21181 tttagtttcg tcaagaagcg cttgactagt catccggtaa atgggcagat ggaaatgact
    21241 accttgcatg gaacgtaggg ttttgagact gtagatgtct gccgacttat ctgaaacaat
    21301 cactcctgta aaacctgctg catccgcagt tcgaatgata gttcctacat taccaggatc
    21361 ttgcacatct tccaaaaaca agaacttgcc ctgactcaaa tcagcttgtc ctacttcttc
    21421 tttttgaacc acggcaacaa ttccctgtgg agtctgagaa tccgccaaat ctagcaaaat
    21481 atcctctgaa atccagacag tttgcggaaa agcagctaac tgatttcgat aattttctag
    21541 ggcaaagatt ttctcaatcg tcactccagc ttggacagct tcttcaaaca agtgccagcc
    21601 ttcaatcaaa taggcagact tgcggtattt tttttggtgt aatttcttgg cattttttac
    21661 cacagaattg gcttttgagg ttataatagt catagaaata ttataacaca atcaaagggg
    21721 tttggtatgc aaaaggttag aatgattgcc caaggtaggg tgcagggagt cggctttcgt
    21781 tggggtgttt atagcctggc ccttgaaatc ggtggcatca caggtcgggt atggaataac
    21841 gacgatggca cagtggaaat cttagcccaa gcagactcat ctgctatcat ggcaaaattt
    21901 atccaagaaa tccgaaaagg accgacacct ttttcaaaag taagctactt agatgtcaaa
    21961 ctaagcaact ttcctcccta ctctgacttt aaaatcgcaa attaggtctc cagaactatt
    22021 gtatattttg taaaaaaaca gtagaataga aaggtataat ttttaaagaa ggaataaaaa
    22081 cagtgaaatc tattaaacgt tttgcattct cggctatggg agtggctatg ttgcttgtct
    22141 tgactggctg tgtcaatgtc gataaaacca caggtcagcc aacaggattt atttggaata
    22201 cgatcggagc gcctatggct gaagccatca agtacttcgc tactgataaa ggtctaggct
    22261 ttggtgtcgc tatcattatc gtaaccatta tcgtacgctt gattatctta ccacttggta
    22321 tctaccaatc atggaaggca acgcttcact ctgaaaagat gaacgctctc aagcatgtcc
    22381 ttgagccaca ccaaacacgt ctcaaagaag caactactca agaagaaaaa ctcgaagccc
    22441 aacaagccct ctttgccgct caaaaagagc acggcatcag catgtttggt ggtgtaggat
    22501 gtttccctat cctccttcaa atgcctttct tctctgctat ctactttgct gcccaacata
    22561 ctgaaggggt tgctcaagca agctacctag gcattcctct aggttctcca agtatgattt
    22621 tggttgcctg tgctggtgtc ctttactatc ttcaatcgct cctttcactt cacggagtag
    22681 aagatgaaat gcaaagagaa caaatcaaga aaatgattta catgagccca ctcatgatcg
    22741 tcgtcttctc cctcttctca ccagctagtg tcacacttta ctgggttgtc ggtggtttca
    22801 tgatgattct ccaacagttt atcgtcaact atatcgttcg tccaaaactt cgcaaaaaag
    22861 tccgtgaaga actagccaag aacccaccaa aagcaagtgc tttctctaaa ccaagtggac
    22921 gaaaagacgt tacccctgaa caaccaactg ctatcacaag caagaaaaaa cacaaaaatc
    22981 gcaacgctgg aaaacaacgt tcgagataag aagaaaaagg cttagctaat ttgctaagtc
    23041 tttttgcaaa tcaaaagccc gatgtttcca tcaggcttct tttctatcca tgtacacgtt
    23101 tcatataatc ttgataactt tcggtatcca tgagtttttt agcgttcttg acgcgatctg
    23161 ctgttggtgg tttgactcct tcgagggaat atggaattcc aagttcacgc cacttgaact
    23221 cacccatggt gtgataaggt agaatttcaa acttatcaac atttttgagg gtcttgacga
    23281 acttaccaag ttcaatcaag tcatcatctc tgtctgtcaa tcctggaact agcacgtggc
    23341 gaatccagac aggttttcca atatctgata gatactgggc acaagccaag atatttttat
    23401 tagtttggct agtgacaatc ttgtgctgtt cttcgttgat ttccttgata tccaaaagaa
    23461 ccaagtcagt gacagccatg agtttgtcaa acttctcaag gtaacgtggt ttattacgga
    23521 aaggaagagc acaggtatcc aaggtacagt ggattccttg ttccttagcc ttggtgaaga
    23581 gagcaatcag gaaatcaatc tgcaagagag cttctcctcc actgactgta atcccaccct
    23641 tatttcccca gaaaccacgg tagcgcaagg cctctgtcaa gacatcatct actgtccgtt
    23701 cacgtgactt attggactcc atagcccaag tgtctgggtt gtggcaatac tggcaacgca
    23761 tgtgacagcc ctgcaaaaag acaataaagc gaataccagg cccatctact gacccaaagc
    23821 tttctgtcga atgcaccatt cctgtcactt gtccataatc aattgtttct tcagacatat
    23881 cgttaccttc cttgaaaacg ttttatagtt ttattatatc acgacttgaa ggaaaaacaa
    23941 gatttttgcc tattttttag aaagcaatct gtttttcaat ttcattttca atctattatc
    24001 agattattct tcaaaatcga agccatataa ggttgcaaaa tagtcctcag ggcgctctgc
    24061 acggcggatt tgacgggctt taccttcttc ggtatagagg atttccgcag aacgtaattt
    24121 ggcattatac tggtagccca ttgaaaatcc gtgggcacct gtatcatgaa ttaccagcaa
    24181 atcaccgatt tctgtatgag gcagttcgcg attcactgca aatttatcat tgttttcaca
    24241 gagtgaacca accacatcta ccgcttcagc tggtccatct ggatgggtca cgttgctaat
    24301 atgatggtaa gctccgtaca tagctggacg catgaggttg actgctgagg catccacacc
    24361 tagataggta cggtaggttt ccttcttatg agtcactctt gtgactagag caccgtgagg
    24421 tgccagcata aaacgaccca attcggtgaa aatcttgacc tgaccaagac ctgctgacgt
    24481 aagaacttct tcatacacct tacgaactcc ctcaccaatc aaggcgatat cgttcggctc
    24541 ctggtctgga cgataattaa caccaatacc gccagaaaga ttgataaagt ctagcgaaat
    24601 gcccaacttt tccttgattt caacagccag ttcaaagagc tgacgagcca actctggata
    24661 atagagatag gtcacggtat tggacgctag gaaggagtga atcccaaaag tcttggctcc
    24721 tttttccttc aagatagcaa aggcttcaaa gagctggtcc ttggtcatgc caaacttagc
    24781 ctccccagga ttgtccataa tgtctgtccc cagttcaaaa acgcctccag gattataacg
    24841 acaagagatg atttctggaa tgcctgctac tctctccaga tgttcaatat cttcaaaggc
    24901 atccaagtta atggtcgcac ccaattcacg tgcataggcg tattccttgt ctggcgtgtt
    24961 gttggaagag aacataatct cagaacccag aaagtccagt ttatggctca tcaaaagctc
    25021 tacataacta gagcagtcca caccacaacc ttcttcttgg agaattttca aaatagctgg
    25081 agttggagta gccttaactg caaaatattc cttaaagccc ttgttccacg aaaaagcttg
    25141 gttgacggct cttgccttct cacgaatccc cttctcatca tacaagtgaa agggagtcgg
    25201 gaactcggca acaatcgctt ctaactcttc tctattgata aatggtgttt tcataagctt
    25261 ccttctattc tgtttgcaaa gaaaggctgg gacaatcgtt ccaaccttta gttctatctc
    25321 ttatttatct tcgtcaaaga tattgccaac ctcaacatcg atggcttggt tcttgacatc
    25381 aatattggtt accttcaaga gtgacttgta gtcaaactgc ttttcacgtt cttcttgggc
    25441 attgtccgca aagaccgcta cacctgccag ttctgagtcg aactcgcgca agagactaat
    25501 cataccattg accgttccgc cacctttcaa gaagtcatcc acaatcaaga cacggctgcc
    25561 tgccttaaga ctacgttttg aaaggaacat tttctcgata cggtcaccac ttgaacctga
    25621 aacatagttg acgctaacag ttgaaccttc ggtaattttc aggtcacggc gcacaatgac
    25681 aaaagagaca ttgaggacat tggcaactgc atttgcaagt ggcacaccct tagttgctac
    25741 ggtcataacc gcgtcaattt tttggtccat aaagcttttg gcaataatac gaccaatatt
    25801 tttcaagatg gctggtgtgc taagcaaatc agacagatag atataaccac ctggcaagat
    25861 acggtcactt tctgacaact tggtacgcaa gtcttcaacc atttccttag catcctgact
    25921 cgaaatagac ggtgtgaaga tgacacctcc gccagcccca gtcactgtct ggatatgacc
    25981 gatttcaatt tcctcaaagg cgcgtttgat aatgacgata tcttctgaga tggatgattt
    26041 agcagactca tacttttcag caaaagtatt gagactagtt agtttataag gattattaat
    26101 caaatagttg gaaatgacaa ccatccgatc acttcttctt aatttcattt ctatttccta
    26161 ttccattttt attcaaaaaa tcaaaaagca aactagaaag ctggtcgctg gtggttcaaa
    26221 acactgtttt gagattgtca atagaactga caaaccctgt aatatacctg catatataca
    26281 tacgacaagg cgatactatc ctagtttgaa gagattttcg aagagtattc atttttgtct
    26341 tttacttatt ataccatatt cacataaaaa aacgaacatt cttatcctaa aaaatgctca
    26401 tttttcttaa attatcaatc taaatctggt ttatagaagg aacgattatc catagcgaag
    26461 attttattgg tcatctctcc tttatccacc aaagccagag ctgttgacat catcatcatg
    26521 cttgcatcca gattgtcaat catatggata atctctgcct ccataatacg tggacggact
    26581 ggacttccat attcaagcaa gccgtggtga ctgaggatga catgacgaag caaaacgact
    26641 tcttccttgg tatcatcgat gccgagttcc ataactgtct tggtaatttc gctatcaatg
    26701 agagcgatat gtccaagaag attacctcgc actgtgtact ctgtctggtc tggccccgtc
    26761 aactcgataa ccttagctaa gtcatgcagc ataatccccg catagagcag gctcttattg
    26821 agctgaggat aaacttcgct aatagcgtct gccaaacgca ccatggtcgc cgtatgatag
    26881 gccaagcccg tttcaaaggc atggtggttg gtcttggcag ctggatagga gtagaattcc
    26941 ttatcatact tggtgtagag atttcggaca atccgttgcc agacaggatt ttcaattttg
    27001 aaaatcattt gcgacatgta gtcacgaatt tccttgacat caactggtga cttgaccttg
    27061 aaatcagctg ggtcattggg ttcaccagct tgaggcaggc ggagagtaat ttgattgact
    27121 tgaggggtat tgttataaac ttctcggcgt cctttcatgt ggacaacctt acctgcggta
    27181 aaggcctcaa tgttatgagg ttgggcatcc cagagcttcc catcaatctc gccactatca
    27241 tcttggaagg taaaggctag gtagtttttc ccagctcgag tttgcctcag gtcagctgat
    27301 ttgattaggt aaaagccttc aaataactca tcttttttca tgtgactaat cttcatattc
    27361 ttcctcattt tcttgaaaat ggagtagatc aagcgcaggc tcaccttctg acaactcaat
    27421 gtgacggagc gtccgctcga tagctatggt acgacggttt aataattcat caatattgcc
    27481 agaggcatgt tggagatgtt tttgtgcctt gaccagaata ccaccaaact tgccaaactc
    27541 ggtcttgaca ctggcaagag tcttgctgat atggtcggca ctcttttgga tattaagggt
    27601 cttgaaacca actgataggg agttaagaag ggctgatagg gtacttggtc ctgcaacgat
    27661 aatctgttct tcccgtctca aatcatcaaa gaagaccgga ttgcgcacaa tctctgaata
    27721 aagaccttct gtcggaacaa acaagattcc aaaattggtt gtccgaggcg gtgctatgta
    27781 cttgctcttg atatccttgg caaagcgctt gacgcttgct aggagtgact tacgacagcg
    27841 ttcaatctca tccttgtcac ctgtctcata ggcttcttcc aagcggtaat aatctgccag
    27901 tggaaactta gagtcaattg gcagatagac gtattcttgg tcgccttgtc cgggtaactt
    27961 gatggcatac tccactcgtt cactagagtt ttcaaccgtt gcgtattctc gttcgtactg
    28021 ggcaggtgtc atgatgtctt caataatttg ccccagttgc aattctccca gaatacctcg
    28081 cgtcttggtt ccagagagaa ccttgttaag agctccgaca tcacgggcaa ctgtctgcat
    28141 ttctccaagg ccacgattga cagactccag ttgtttagaa actgtttcaa aggaagcctg
    28201 taagcgtgtc tgcaaggtct tttctagttt ttcctcgacc gtctggcgca tttgttccaa
    28261 acgttgctca tttgattcct gcaaggcttg gagacgttgg tctgtcttgt ctctagtttg
    28321 gaggagatta tctgtcattt cttgacggac ttgggtcagg ccttggtgca attcaatccg
    28381 cacttcttgc aaacggtcgc tgacagccac ttccaaatct ttttggtcta actggctggc
    28441 ttgtctggct tggtcaaagc ggtaatccaa ctggtctgac aaatgatctg cctgatcctc
    28501 caagctctta cttaagtgtt tctcctgcct atcctgcctt tgccaaatca gaaagagacc
    28561 agctaggttg gcaattaata atagaataag taaactttcc atcctacctc ctgtccttgc
    28621 tatgcagtac gaccacataa ccatctgggc aagttaccga cacttcccta tctatatatt
    28681 cgttagaagc gtacactttt ttaaagaaaa aattctcctc tgtcaactca tacttagctc
    28741 caagaatagt cagctggcta tcccgaactg gcataaaggc tagatagtcg tagtctgaac
    28801 gaggttctag ctgactggtc ccttctgaac aataggcaat caaattttgc ccatcctcaa
    28861 tttctatttg acgcatatag ggtgccaact taggattgct aggtagaaag acattggcca
    28921 acatatggtc aatacggcca cccaaggcac cgaaaatagt gacctgagcc tgaggatttt
    28981 gttcaaagat ggttaagaga gccaattcca gatctgtatc atccttttct ggtcgggctt
    29041 ggacaaaata ctgggcacgt ttttgaatca cctgtcgctc ttcttccgtc acagaatcaa
    29101 aatctccgac tgctagagca agaggtaagt cttcttccaa gacccagagc gagcctcgat
    29161 ccaccccaac aaaagcatca aaatctgtcc gataatgacc gcggtttccg cctgcaaaaa
    29221 ctgcaaccct agtccagttg ttttctgaga gtttgtactc gctcattgac ttctccctta
    29281 aagacatagg aacctgctac aaaaacagtc gcaccagctt ctttggcttg agcaatagtt
    29341 tggtcatcaa tcccaccatc cacttcgatt tcaaagttca aacctttttc ctcacgaaga
    29401 gcaaccaact cacgaacctt atccatggtt tctggcagaa aggcttgccc accaaaacct
    29461 ggattaaccg tcatgactaa aacttggtca actagatgaa ggacgtgctt gatggcttca
    29521 actggtgtgc caggattgat aacgactgaa ggcttaactc cgagtgaacg aattttttgg
    29581 agggcgccat gaatatgagg tgttgcttct acatggatac tgatgatgtc tgcacctgca
    29641 cgcgcaaaat cttccagatg atgctcaggg tttgacacca tcaagtggca atcgaaaacc
    29701 atcttactat gaggacgaag gctctcgacc acacctgcac caaaactgat ttgcggtaca
    29761 aaatgactgt ccatgatatc gatatgggca tattctgccc cagttgcttc tagacgtttg
    29821 atttcacgtt caaagttggc ataatctgct gccagaattg acggagcaat cttgtattga
    29881 gacataggtt tctccttatt ttggaatttt tttgctgact tttttatagg tttctctacg
    29941 attttcaatt tcactaagga attgcaggta attgtcaaaa cggaaggttg caataacacc
    30001 ctcttcaaca gctggtttga cggcacaaga cggctcatgg gtatgggtac aagtacggaa
    30061 cttacaatct cggctaacag tagcaatctc tgggaaagcc tgattgaggt cttcagccct
    30121 tgatacttca tagtccaagg atgaaaatcc tggtgtatct gcgattttac ccccgttgag
    30181 attgtaaaaa ctaacagctc gagtggtatg gcgaccgcga cctagactgt ctgaaatttc
    30241 tcccgtttca agattgaggt ctggtgcgat tttattgaga agagttgact tcccaacacc
    30301 tgtctgcccc ataaagaccg taaccttgcc tgttaacaaa gacaggagtt cctctttact
    30361 ggtcacaaag tcatagccga tgtcaccata ggtctgctgg taaaaatcca gttctcccct
    30421 atcttccaac aaatccattt tggaaatata gacaatggga tggatgccct tgtgctccaa
    30481 aagaaccaag aaacgatcca gcaaattgct gttaaaatca ggttccttga cggacatgat
    30541 tactacagct tgatcgatat tgacaatagg cggacgaacc agactgtttt tccgttcgtg
    30601 aattttgagg atatagcctt ctgaattttc ctcggcagag aaatctaccc agtccccaac
    30661 ataaggggta tggccttttt tacggaaatt cccacgcgcg cgtgtttgat aaacctggcc
    30721 atcactctcc acatagtaga aacctgccaa ggctttaatg atttgtccct gcatcttaga
    30781 gtccttgccc tttaagtgcg tctgctagac cggcaaattc tgccaagctg agagcttccc
    30841 cacgcacact tggtgacaag cctgcctggt ccaaagcctt ggtcagcttg tccttgacct
    30901 cttcagtctt accaaagtaa cctgtcaagt tattccacaa ggtcttgcgg cgatgggtaa
    30961 aactagcctt ggaaacctta aagaaaaagt tctcatcttc tactgctacg gctggctctg
    31021 gacgacgcac cattttcaag atggctgaat ccacatttgg cgctggcaca aagaccgtac
    31081 gaggcacgat aaaggcaacc ttggctgtca tgtaatactg cacggcgata gacaagctac
    31141 cgtaagcctt ggtgttaggc tgggctgaaa tgcggtccgc tacttctttc tgcatcatga
    31201 ccacaaactc acaaaaagga atgccactct caatcaagtg catgagaata ggcgtcgtga
    31261 tgtagtaagg caaattagcc actaccttga ttggcaggtt aggattttta aaattttgga
    31321 tatgttgcgc caaatcaacc ttgagaatat cttcgttaac tacagtcaca ttatcaaaat
    31381 cacgcagggt atctaccaaa attggcacca aacggtggtc aatctcaaaa gccatgactt
    31441 gggctgcacg ctcagccaga aactccgtca aggcaccaat acctggcccg atttcgatga
    31501 cattgacctg gtcatcaatt tcagccgtat ccacaatttt ttgaaggata ttggtatccg
    31561 tcaggaaatt ttgcccgaag gactttttaa aggtaaaacc gtgacgctcc agcactgcct
    31621 tggtcactct ataatctgca attctcatct attctctttt ctattatctg ttactactat
    31681 tgtaacacat tccccttgta ttttgggaat gaaaatcata ccaaaaaact atctttcctc
    31741 atgaagaaag atagtcttgg aaatctttaa aagtggcctt aacagttctc tcgaaacatg
    31801 cgttcaaaaa aatcagcttc ttgataactt cgattttcag gtagggtcaa atccacatcc
    31861 tcctccacat catccactgt cagttcaacc gtctgaggta aatttttcaa acgataatgc
    31921 ttttgccttt gcccttcaat actagcaaaa tcaagcaaat agccatgcac tcggatttga
    31981 accaaaagga gatgattggt catattttcc atgatgagga tatcttctaa accacctctg
    32041 gcactaggat aatcagatac cctgcgaata cggatttttt cacacatgag caagtttcct
    32101 catatcaatg atttcatcag ccttattcca gactagggga ttatgggtcg caatgatgat
    32161 aattcgattt tcatctttca aatccaccaa gagattcata acctcctctg aattttcagg
    32221 atcaagagct gctgttggtt catctgccaa aatcaagggt ggatttttca aaatagtctt
    32281 agcaagggca actcgttggg cctctccccc agataaagta taaatttttt gttctaaatc
    32341 caaataccct agattaactt tttctaaagc ccccacttgc ctttccaaac gttctacttt
    32401 tgagattttc tgaccaacaa aacccaaatc caaattttct ttgattgatt ggttttctaa
    32461 gaggccaaaa ttttgaaaga gatagcccat ctgatctcga aaatactcac gagtgggaat
    32521 ggtttttaaa tctttcccct gatagagaac ccttcctcca tctatctttt ctagctttcc
    32581 caagatattc agcagcgtcg tctttccgct tccactcttt ccgattaagg cataaacctt
    32641 gcccttctcc agcttgagat tcaaaccaga gaaaatcgcg cggtcattaa atttcttttc
    32701 caatccttga atatcaatca tcttattttc ctttcaatac tgccatgcta ccagcttctt
    32761 cttttttgtc ctgccttact aaaatcaaga gggcgttaag cgtaaacaaa gctacaacta
    32821 gagcgctaat caaaccatct cttgtcaaaa tactagatag gactaggcca agcaagagaa
    32881 ctcctccttg cgccagtaaa tacttgccat gaagctcata gattgtcata ccagcaagac
    32941 gtttaatcat aagctcccgt ctgaactgct caaaatagag aagattcatg gaatcaaata
    33001 acaagatagc cgtagacagg gtcaaaatcg tcccaataag gagagagtaa aactccaccc
    33061 gtttgtcatt tagtaccttg gcaaaaaata gctggctttt taccaagtaa gaaaccttgt
    33121 gatacagacc ttgctctttt agagctgtga tgctgtctcc atatcgatct agtttcaagg
    33181 cactattagc cgtagttccc cacaacatcc ctgcaacagg tcttgttcca gtcgcttgcg
    33241 gcgttagaac tacaataatc ggatctttta ggtactggcg tgttgtcttg tacccatcat
    33301 tatagaggaa acgttcctgt cctgtttctg taaaagctag ccttacctgt gggaagtagt
    33361 gtttctgact cgtcacttct acactttcag atgaaaagtt ttgcaggtaa tctgtaaaca
    33421 atccttggta gtaggcagac tgctctcgca agctctcagg caagatcagc ccaaactctc
    33481 cctcagacaa gttttgcatc ttgtcaataa actctgaaga aacggtaatc ttttcttcta
    33541 tcagatagcg cggcgagaca tagataacat tccctgacgg tatgtagtca ctgagacgat
    33601 tgccatctag gtccacttct gctccatctg agaaattgtc aacattgctc ataatataaa
    33661 aagagtctgt attggctaac cgttcttcag taaatgtctg ccactcacga ttatccttac
    33721 gcgttccttc ttcatcggca aatgcactag accaaccaaa ggatagacgg taacggtctg
    33781 aggactggct ccatttattg ctagctctct ccatttcctg catttcacgg tagtggggta
    33841 ggagagctgt cgcactcgat ccgaccacca atacagctaa gagttgcccc accatcatca
    33901 atgtcatcat ccgtttgaga gggagtttcc ctttcaatag atccaccaga ctattttcct
    33961 gtaaaccaag tagatggacg acacttagta aggtagaaat ccctgccagg gtcaatccat
    34021 aaagtagaag agcaatgatg accagttgta ccgttgccat aaacaaggca ccttgatacc
    34081 agagaatccc caatcccaaa agactggata ccagcactga gcagataagc tgtctcacat
    34141 cttctaacac tggtctgaga gcaactccaa acaagctctc accagctatt aagcgaatcc
    34201 ctgcctgacg aagggatttg atccgataaa tcagggtcag actcataaag gtcagcagaa
    34261 aaatagctaa actcagtagc accatagggg tggccgccaa tagtaagact atcgaaaatg
    34321 gatcttctcc attcgaaaca aagccttgat agccaagttc tttcaaggtg gtctgtaagc
    34381 tcactccatc caaacttcct gacacaatca agtaagaccc taataaatca ctcgtttctg
    34441 cactctcctt ggaggaaatg gtcagacctt ctggaagctt tccctcacca taagtggcat
    34501 aggtaaagcg tgtttctcca gcttcatttg gctcaacgat tcgacgggcg atgagactat
    34561 tatgctctac cgccaagtga ctcaaagcct ctgtcacctc ttcgcgacta gctactggtt
    34621 gatttatcat cattcctgtc acatcaacag aaggatagtt accaaataaa atctcttctc
    34681 gatggtcaac ggaagttatc accatataaa gcgataccaa taccattgaa atcaaaataa
    34741 ataaacgttt catcatttcc tccaaaaagt tacttggtca cttagtgaga aggtgaccaa
    34801 gtaaagctaa acaatagggc tataccattc taaacattat agtagaatgc aactttctct
    34861 ccccaagaag tacgaatcca tgcacgagaa gtccctccag caccagcata tcccttgtca
    34921 gatgaaccag tttttctgct aacaactgtt gaactatggt attttgaagg gtgatagtag
    34981 tttgagtaag caccaccgtt acctgaacca taagtccaaa caccaccttc tgggtattga
    35041 acggctgcag aggcaactgc tacacttcca cctaatgttg ctgcaatgct cgctacaaga
    35101 gctaattttt taactgtttg tttcatattg atactcctct atttttgatt acaagattgt
    35161 tgagttactt gctcctcttt ccattatcaa cgttgatact attatattac caaatgatat
    35221 tctaaaatta tttgtttttc tctaaattgt caaaatagca ccctgaaatg aacttttata
    35281 gtcattatac tccatcttta tcacactatc aaggacatca atgtccttaa aatctaacta
    35341 tttcatatta tttttagctt atatctaaaa aaacagttct aaagacgaac tttagaactg
    35401 ttttgatacg aggacaagga catttttgtc actgattcac tatgtttata aatatttttt
    35461 taaatcttct tgccattgtt tttctaacat agtaactaaa taagaatttt ctattatatc
    35521 agcaaatagc ttcgatttct gatagaactg ttcggcagaa acataatcat tgtttattat
    35581 tagagataat ttccactcca acattaatat aattggtttc ttctggaaat cttgtgtttt
    35641 ttccattata tgattaaggc taaagatata agctcctagt gaatcataag acgacaagtt
    35701 atccaaacag gctagacccg aaaacaaagt gttacttaaa gcaaacagat attctgatgc
    35761 aattaattct acatgatttg tcaaacgaac taaaaacgaa tgaattctgt taatttcttc
    35821 aatctgattt tgaccttgtt ttatctttgt aagcactata gcaaaatata agttgataac
    35881 ttctaattca tttatcaaaa acaattcctt atcataaatt gttttaaaat aatcgtccag
    35941 tacggtttcc ccgtattctg gtcgtccact tcgaataaca tctatcgttg ctctagtagc
    36001 ttcaaaccat actttttcct cattaggaag ttgctcataa aataaatcct ctatctcttc
    36061 caaacacgct tccttcttat cgtactcctc ttctttacca tagattggtt cacgtaaaat
    36121 ctggtatttc aattctaaat aagcagaagg aagagctgaa aaatccggca taaggctata
    36181 aactggaact cctagccggc gagcaatata ggctaacttg ggcaaactcg gttgcgaagc
    36241 tccactttca attcgcgaca gttgacgaac tgtcagttct tgctcatctc cacaaaaatc
    36301 tggacgacta attccttttt ctatccgaat ctctttaatt ttttgaccaa ttaacatcag
    36361 acgcctccta ttctacctgc ttcgaaaaat actgtgaaac ttaaaaaatt gtaacggcta
    36421 catctttcct actcataaga tttcatagct tcttccactt ctgccaaagt aaccccaaac
    36481 aactctaggc gtttgaggag ttgcttgccg ttggaatagc cgattcggag agtctctccg
    36541 aggtattctc tacgcttacg gctgtctgcc cctgctagaa aaccaaggcg aatcaaatcg
    36601 ctacgactaa tgtcaaactg gctctcatgt tcaaattgtt ctgtcacctg agctagagcc
    36661 gttttcaggt cttcatagct ggcatgctca attcccagag aacgcccctt ggtcttggac
    36721 ttgggaacag cttcatctcg cttgagaaag gcatgctgaa ctgttggaat gaccgtcatg
    36781 atcatgcgcc gaatccgttc tccattaaaa tctgggtctg taaagacaat gactccatga
    36841 cgttggtgca ggcgctgaat ccgctctata tcctgatcat tgatggcaga acctcgagtc
    36901 tcataggtct ccacatcgaa ataacgcttg agattgaccg tatcatcacg cccttcaacc
    36961 acgataactt gagaaatttt ctctttcatt acttgctgtc cagtccaaaa attcgttctg
    37021 catttgcagt cgttgctacc gccagctctt ctgtcgtcat accacgcaag tcagcgataa
    37081 agtcgaccac atagcgagta taggctgttt tattttcacg accacgcttg ggtacaggtg
    37141 ctaagtaagg cgcatctgtt tccaccaaaa tcttgtccaa aagtaactct ttagctgctt
    37201 cttggaggtc agttgccttc ttaaaagtca ccactcctga gaaggaaatg gtcataccaa
    37261 gatccacaaa cttctctgcc cactcaagcg tccctgaaaa tgaatgcatg ataccaccac
    37321 gaggaccaac gccctcactc ttgataatct cataggtatc ttccagcgca tcacgggtat
    37381 ggacaacaaa aggcaaatcc aagtccttag atagctgaat ctgacggcga aaaacctgct
    37441 cctgcacctc tttgggcgct gtcatccaat ggtaatctaa gccaatttca cctaaagcca
    37501 caaccttggg atgttttaac ttatccaaca agtaagcctc aacttcctct gtataagtac
    37561 cagcttctgt aggatgccaa ccaatagtcg catagagctg atcatactca tctaccaact
    37621 ccaaggcacg ctcaatcgtc ggtttatcaa aaccaacaat attcatctgt gtcacaccca
    37681 tctcagcagc caaggcaatt tcttctgcct cacgacctgc aaattcttct acattcaagt
    37741 gtgtatgtgt atcaaaaatc atctcttcta acctcgtttt ctatcttcta ttataccaaa
    37801 aaagaggagg ggcacctaat ttttcggttt cccctcctct cttcaataga gagctattct
    37861 gctatctttt ctatccgata ttgcccatct cctattccac agttagagac agaagagatt
    37921 ggctacattg atagaatatt cctattcagc taaagtatgt gattatcttg ggttctcact
    37981 tttctcaccc atcactagga ttgatgactt ctcaaaatcc cccttataat ctaactttaa
    38041 gtagagaata gaattttcta gctgttctat tttctacgtc tagtctttct tcctagcaaa
    38101 gcaaaaccac ttgttgccac cactagacca agactagcaa gtgctgcact tgatgctgaa
    38161 cctgtgttag gtaattgttt gccagcaggt gactggtagg taacatcttg cattgttcct
    38221 gcagttgctt gcggtgcact tgttgtctta ggagcagcat taggagccac tggtctctta
    38281 ggaactgtaa ccatggcaat ggcttgcact ccaatcgttt ctgcttcctt cacatcttcc
    38341 atagttttcg cattttcaat ctctttgaga gctgcttgtt tttctgcttc cactcttgct
    38401 aaaagttctg ctttttcttt atcagaaagc ggtgcgcctt tgatttcatc ctgcttgtcc
    38461 ttggctgctt tttcaatggc atttttagct gattcttttt cagtagctaa ttgcttagaa
    38521 gcttgtgatt gagctgagtt ttgtgaacct gtgtgagctg atccacccgc ctggctacca
    38581 ccgccttcat tcgcattagc atctgagctt ccagtattgc ctcccttatc tccacctggt
    38641 gtattttcta gcttatactc tggtgtagct tcttgagtta cagattcacc tttcgcagat
    38701 tgttgaactg tatcttttcc tagaatcgtc actactgaac catctgggaa tgtgattgtt
    38761 gctgtaccat ctccagctac ttcaacttta tagtaaaata aaataataac aggacaaatc
    38821 gatcaggaca gtcaaatcga tttctaacaa tgttttagaa acagaggtgt actattctag
    38881 tttcaatcta ctataacatc gcttccgaat ccatttgcat ctactgaact tttttacaaa
    38941 aataaaaatc agtagactcg agttcctact gatttttgat agaattcgtt tggattatgc
    39001 agccaaaact ttgcgtcctt tacgacgacg agctgccaat acgcgacgac catttttagt
    39061 tgacatacgg ttacggaatc cgtgtttgcg cgcacgacga agtttacttg gttgataagt
    39121 acgtttcacg atgaatacct cctcatagat tttgtattcg tttagccggc tataaagtga
    39181 tcagttacta aacatacttt actattctat ctgattcttt cacttttgtc aatagcccta
    39241 ggcaaatgtt tccagctttt tcgaatgcaa gccctatcta cgatactgtt tcaagaaacg
    39301 agtcatcttt tcttggattt gggctaactc atcaacacga ggaaggtaaa cgatacggaa
    39361 gtggtctggt tcctgccagt taaagcctcg accatgaacc aagagaacct tttcctgctt
    39421 caagaaatca aggacaaact gctcatcatc atcgatacgg tacatattgc ggtcgatttt
    39481 tgggaagata tagagccccg ccttgggttt aacggcagac aaacctggaa tatcttgaat
    39541 ggcattatag atgaaatttc tttgctcgta gattcgtcca ccaggaagaa gcaattcatc
    39601 gactgattgg tgacccccca aggaagtttg tacgacttgt tgggccaaaa cgttagagca
    39661 aaggcgcata ttggacagca tattgagccc ttcgatatag cccttaacat gagtcttagg
    39721 gccagacaag accatccaac ccacacggaa acctgctatg cggtgggatt ttgacagacc
    39781 attcatgctg acacagaaga catctggtgc caagctcgcc acaggcgtat gcacatgtcc
    39841 gtccattacc atgcggtcat agatttcatc cgcaaagata atcaaatcgt tttgacgggc
    39901 aatctcaata atctccagca agagtttctt aggataaagg gctccagttg ggttatttgg
    39961 attgataagg acgattgcct tggtattgga agtgattttt gacttgatat cgtcaatatc
    40021 tgggtaccat tcaacagctt catcacagat atagtgaacg gcatttcctc cagctaggct
    40081 gacagccgcc gtccatagag gatagtctgg cattggcact aagacctcat ccccattgtc
    40141 caaaagcccc tgcatggaca tgacaatcaa ctcactgaca ccatttccaa ggtaaatatc
    40201 atcaatatct acgtttggga atttcttcag ctggcaatac tgcatgatgg ccttacgggc
    40261 tgagaaaatt cctttggagt cagaatagcc ttcactatca cgcgcattca taatcaagtc
    40321 atgaatgacc tcgtctggcg ctgtaaagcc aaattctgct ggatttcctg tattcagacg
    40381 taaaatcttt tctccattcg ctcgcatccg catggcttct tccaatacag gaccacggat
    40441 atcataagca acatgctcta acttactaga cttgttatat tctttcatct tgtttcctca
    40501 attcatcagg atagtaacat tataccacta gaaagagaat gcgacaagtt tactgaaatg
    40561 tgttactagt ttcgtataga agaaaaacct tgctaaaggc gaggttaaga acgtagagat
    40621 agcaggtatt ttgcaaagac acatcacata ccaaaagata aacctagaaa aagcaagcct
    40681 agaaaggagt cataaagaag attaaacatg aggaaaagcc cccatatcat caagtaatcc
    40741 caacgcccac ttcgttttgc aactagaaat aagattagat ggtagagtac atgaaaaact
    40801 aaaaatccaa taaaacttgg ataaagaagc ggtaccagac tctctaattg acagatcatg
    40861 atcacttcta ccaagactga aactaggata attccataat aaaggaaatt tgatttttga
    40921 aaagagtttt tcatcattct cccttccttc acttctttcc tgctatcctt tcttttattt
    40981 tatcatatat ttatatagag tttaagccct aatattcttt tgaaaaatac tttttttgct
    41041 ttacttctat agtgaaaagg tttacaatta tagtaagaaa atttcaggag gtttcattat
    41101 ggcacaacgt taccaaaata tcatggtcgc aatcgatggt tctaaggaag cggacttggc
    41161 ttttgtcaag ggagttcatt ctgctctacg aaacgacgct aaactcacca tcgcacatgt
    41221 cattgacaca cgcgctctcc aaagcgtatc cacctttgat gctgaagttt acgaagaact
    41281 ccaagtcgac gctgaaagtc tgatgaaaga gtacgaaaaa cgtgctaaag atgctggggt
    41341 agcagatgtt catatcgtca ttgaaatggg aaatccaaag accctgctag cacgtactat
    41401 tccagatgcc gaggaagtgg acctcatcct cgttggcgca actggtctca acgcctttga
    41461 acgcctcttg gtcggctctt catctgaata catactccgc catgctaagg tcgatttgct
    41521 ggttgtgaga gaacaagaaa aaaccttata atcacaaaga aaaggagccc ctagctcctt
    41581 tttgtttacg atttatttct ctctttatgg cgttcgtaag ccttgagctg gcgctgcagt
    41641 tcctttttaa tagcaggttc tggagcatat ttttcttccc aattatctgg ttttaagatt
    41701 ttatgggtca ctggatcaaa atgagccttg ccatctggaa aaattttccc catattggcc
    41761 tgatggacaa tatcaaaaat acgttctggg tccaccccca tcaagacaaa actgccgtag
    41821 gtgaagtaaa gcgtgtcaat caaggcatcc acttgcccta tcaaatcttg ctgagcaggt
    41881 gtcttcttgg ctactttatc tgctgcctta tcaagggcct gatgaagttg cgatacagct
    41941 tgaccaaaat cttcttcaga aggactggct gctcgaacaa actccaccaa ttcttctatt
    42001 ttaaaaccag ccctatgggt tgcaccctct aaatcccaag ctcgaggttc ttcttgggtt
    42061 cgttcatcca tcatgtggtg gaaggtcttg accttattga aatgatagtc acggctgaca
    42121 aagacttttt ctgaagacaa aacaccaaaa tgttccaagg ccttgtggat cccatcttgt
    42181 tgattgctag tggtaatgtg cttggcagct tccttgacac tgctactacc atttcccata
    42241 gcgaccgaca taccgacgcc agccagcatt tcaaggtcat tatctgagtc accaaaagcc
    42301 atgacttgat tgaggtcaaa gccatattct ttcccaactc ggcgaatgcc ttctaattta
    42361 gaatttccct gattgatgac atccgatgca aaaggattgc tacgtgtcaa tttcaagtct
    42421 tcaaaatcag ctgccgcctt ctcagattct tctggtgtca tcagcatcaa aacttggtag
    42481 ataggctgat tcatcaggtg aagcaggtcc tcttcctttt ggggaacaac cttgctgacc
    42541 atgcgattaa aagactgact caccgtccga gttaaaacag agggaacgaa gcgactaatt
    42601 cgttgggaaa aagaacccag accaaaggac atgattttag aacccaacat ggcatccttg
    42661 gtccctaggg caatctccgt gccctctttt ttagcatagc taattagatg gcgcaaatgt
    42721 aacttggaaa tagggctcgt gaacaagact ctgtctttac taaagatata ctggccatta
    42781 taggttaccg caaaatccag atccaaatcg tccatcaatt ccttaacaaa aaaaggtcct
    42841 cgccctgtcg ctacgccaac tagtacccct tgttctttga caatcttaat cgcatcctta
    42901 gtggatttca aaacactctt gcgattgttg accaaggttc catcgatatc aaaaaaaaca
    42961 gctttgactt ccatcctatc ccaatctccc cttttgtgat acaatgatta taccacattt
    43021 cagaaagagt tagtaaatca tgcctaagaa aatccttgtt ttacatacgg gtggaactat
    43081 ttccatgcag gccgatgctt ctggcgctgt tgtgacgagt tcagataatc ccatgaacca
    43141 tgtgtccaac ccacttgaag gaatccaagt ccacgccttg gactttttta accttccaag
    43201 tccccatatc aaacccaaac atatgctggt cctctaccag aaaattaaag aggaagcaga
    43261 taactacgat ggagtggtga tcacacacgg aaccgatact ttagaggaaa cagcctattt
    43321 ccttgatacc atggaagttc cccatatgcc tatcgttcta acaggagcca tgcgtagctc
    43381 caatgagctc ggtagtgatg gtgtttataa ttacctaagt gctttacgag tggccagtga
    43441 tgacagggct gctgacaaag gagttttggt cgttatgaac gatgaaatcc acgctgccaa
    43501 gtatgtcacc aaaacacata cgactaatgt caacaccttc cagactccaa cacatggccc
    43561 cctcggtctc atcatgaaac aggaaatcct ctacttcaaa acagctgaac ctcgtgttcg
    43621 ctttgacctt gatcacatac aaggtttagt ccctatcatc tcggcttatg ctggtatgac
    43681 agatgagctg attgatatgc tggatttaga acacttggac ggtttgatta tccaagcctt
    43741 cggagctggt aatattccca aagaaacggc tcaaaaatta gaaagccttc tgcaaaaagg
    43801 aatcccagtc gctctggtat cacgatgctt taacggtatt gccgagcctg tttatgccta
    43861 ccagggtggg ggcgtacagt tgcaaaaagc aggcgttttc tttgttaaag aactcaacgc
    43921 ccaaaaagcc cgcttgaaac tcctcatcgc cctcaatgcc ggactaacag gacaggcttt
    43981 gaaagactat atggaaggct aatactcttc gaaaatctct gcaaaccacg tcacgtcgcc
    44041 ttaccgtatg tatggttact gacttcgtca gttctatcta caacctcaaa aacatgtttt
    44101 gagctgactt cgtcagttct atctacaacc tcaaagcagt gctttgagct gacttcgtca
    44161 gttctatctg caacctcaaa acagtgtgtt gcacagcctt taaccagccg cctagtccgc
    44221 tctatggtat tcattaagtc aacatctctt gtttaagagc acaaaatcag gaaatcttct
    44281 cgattccctg attttttcta tttacgtttt cgtgttgagc tacgttctgt caaaccatga
    44341 ggtaagagaa cttcacgttc ttccaactct tccttatgca taatcttggt caacatacgc
    44401 atactaatgg caccaaggtc ataaagaggt tgggcaatcg ttgtcaagtt tggacgggta
    44461 aagcgtgaga tttgtgaatc atcactagta ataatttcaa aatcttctgg cacagaaaca
    44521 cccttatcag ccaaaccgtt caagactcct gctgccaact catcacctgt cacaactgct
    44581 gcagttgcat ttgatgaaat caaacgctct gctaaggcgt aaccatcatc atagctatat
    44641 ttagattcaa ataccaaacc ctcactataa gcgattcctg cttttttcaa ggtttccttg
    44701 tagccaacta aacgaacctt accattgatg tcatccacta gcggaccgct aacgaaagca
    44761 atacgctcat tttctttagc aaggtaactc actgcatcaa ttgttgcttg cttatagtca
    44821 atattgacac ttggcaactg gtgctcaaca tcgacagttc ctgcgagaac aatcggagta
    44881 cgtgaacgcg aaaattctga gcgaatttta tctgtcaagt gataacccat atagataatg
    44941 ccatctacct gctttgaaaa gagggtattg acaacagaaa cttctttctc gttatcttca
    45001 tcgctattag ctaggacaat attgtacttg tacatttctg caatatcatc aatcccctta
    45061 gccaaactcg aaaaataacc attggtaata tttggaatca cgacaccgac agtggttgtc
    45121 tttttacttg caagaccacg cgcaactgca tttggacgat aatccaaacg atcaattacc
    45181 tctagcactt ttttacgggt attctctttt acatttttat tgccattgac cacacggctg
    45241 accgtcgcca tggaaacacc tgcttcacga gcgacatcat aaatggttac tgtatcatct
    45301 gcattcattc cttttcctgt cctttctatc tcacacattc ttttacaagt agaggtactg
    45361 attgaagctc tatatctact tacaaaagtg aagatgtgaa aatttcgttt tcatatttct
    45421 acttattcca ttctatcact aattgtaaac actttcaagt gttttttgaa gattgattga
    45481 aaaaatttca tagaaaacct aggtttagct ccttgctacc accttagact aaacaaaaag
    45541 gaggaaacta agccctccta aagttatagt aaaatgaaat aagaacagga taaatcgatc
    45601 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
    45661 catctactat aggtattgtt ccattcacta ccgtcaattt tagcacatag tcttcatgaa
    45721 aatattatat catcataacc aaccagattc ttttgcgata ttagctgcct ctgttcgatt
    45781 accagcatcc agttttgaaa gaatattggt gacatagttt cgaatagttc cgtttgagag
    45841 gtaaagctga tctgcgattt cttggttgga taagccccgg gcgattccct ttaagacagc
    45901 aatctcttgt tctgtcaacg gattgggacg ggtcatcacc acttccatca attcaggcga
    45961 atactccttg cgtccttcga ggacggtgtg caaggtttgc atgaggtctg caatgcttcg
    46021 ttcctttaat acataagcat ccactccagc cttgaccgca cgttcaaaat acccagcacg
    46081 cttgaaggtc gtcaccacaa ccacctttgt ttcaagcctt tctgatcgta tccactccaa
    46141 gacttcaaga cctgtcttaa caggcatttc tacgtcaagg atggtgatat ctacagactc
    46201 cttttctaat agttggattg cttcttgccc atttttggct tgaaggacag actccacatc
    46261 tggttgaagc gtgagcaatt gacacatggc atctcgcaac atactttgat cttctgcgac
    46321 taatactttc atcttagttt ctctccttat aaggtagtcg aacttgcact tccgttggat
    46381 gtttctgact gattacactt acttctcctg aaaatggaaa aacacgttct cggactgtat
    46441 ggagctcatc tccttttaga aaagcaaagc cgcagccatc atcacttact gttaaaatga
    46501 gttccttctc tgtccgttct aattttaagt aagctttaga cgctttggca tgtttgatga
    46561 tattggtcac caactcaagc aaaatcatag aagccattga ctccaattct tgagtaaggc
    46621 tagcagtatc tagttggtta tctgtttcca cctcaattcc agcaatttct aacatctttt
    46681 tcacagtctc tagttcggat gtcaaagttc tagacttaag attttccaca atggttcgaa
    46741 cttcacgcat tgattctttg ctaatttgct gtatttctct taattccttt tccacttgtg
    46801 gataagcctg catttgaaat agctgcaagg ctagatctgt cttgacacta agcatagcaa
    46861 aggtatgtcc cagactatca tgcaaatcct gaccgatacg attgcgctca ttttctgcta
    46921 gcaatagatt tatctgggta ttttgcttga cctgagcttc tttcaaatcc tcgacaaggc
    46981 gaattcgaac cgagcccaaa gtcatcaaat cgacaaaagt aagaattaca agcatataga
    47041 ctagaaactc aacttcgatt ctctgaaaaa tcaaaagtcg ccccacaaca aggacttgag
    47101 caaggagaaa tgtccataca tgtaaagact ttaaactacg tacgccaaaa tgataaatta
    47161 agagattgga aaggaaaaat aaaaaccaga tataattccc agcaacaaag acggtattcc
    47221 cagctacata gaccagcatg atcccccaga aaagccaaga taggcgctgg ttcttagtta
    47281 ttaaaacacc caaatacgtc actacaaata gaatatcaac caataaatgc caagcaggaa
    47341 gctccccaat cactacaggt aggatgggaa aaagcataaa aatcaaactg gcacaaaaca
    47401 tatagtgtat gcttttcagt ctttcaagca ttaagcattc tccttatgac cttgaaggta
    47461 aatagtcaaa ccaaataaaa ctgctgaaaa aacaagtaaa taaactgtgg ctgatagatt
    47521 gatgccaccc tcgtttaaga aggtcttgag caactccatc aactgataag ttgggagaca
    47581 cttaccgatc gcttgcatcc agtctggaaa taaagagata ggcatccaga gtccgcctaa
    47641 aacagccaat cctagataaa gaagattgcc cacaacagac atcagctgac tagttggtaa
    47701 gagagtcaag gtcaagccaa gggctacaaa agctacactt cccaaaataa gcaaaatcgc
    47761 agccccaacc cagcttccta gaggaatctc tacacctctt acaaagtgcc caactgagaa
    47821 aaccaccaag attgaaacca aataatcaac cagcatactt gttatctttg atagataata
    47881 ttctaccata tttacagggc tatgacgtaa tgttttctgc cagttgttga ttttatctgt
    47941 atgtaaaaca gctgggaatg aaaacatagc tgtcgacatc atggaaaagg ctgtcatgga
    48001 gatgaggtaa tcacgcataa aattagctgg tccacctggt gtctcctggt agatgccaga
    48061 aaagaataaa tagaaagccg tcggcattcc tacggataat aaataataga cgagttgccg
    48121 tttggtcaat aaaaattcta tcttatttaa tgctatccat cgtttcatct tagtcatctc
    48181 ctttttgcgt ttcttcaaag attgtatcca gcaaactacg attattaact tcgatttctt
    48241 gcatcctaca tcctgcttgg gctaatagtt cccagaaagc atctgcttct cgagtgacta
    48301 cttgtaaaga atcttgcttt agggtccagt tttcaaccaa atttgactgc tctacgactt
    48361 ccttgtaagc tataggaagg ataaagtgct tttctatttc ctcgctacgc atagctagag
    48421 gcgtcgtatc tcgaatcaac tctcccttat ttaagagcaa aatgcggtct gcagtgtgtt
    48481 ccacttcctc aatataatgg gacgaataga gaatggtgac tccttgcgct tttaactcct
    48541 ggacaatttc ccaaaaacgt tgacgagttg aggtatccat ggacgcagta ggctcatcta
    48601 aaaaaacaat ctttggtcgc ccaattaagg tcaagacgaa agaaaagaga cgcttttgac
    48661 cgcctgataa tttttctgcc aactgttctt tttgttgctt gacaaactgc aatagttgat
    48721 caatttcctg attgctcaaa ggatttggat agatacgttg aaagaaagca atcaactctt
    48781 taacttttaa tttctgaacg attacatttt cttgagggag gtaagcccta gtatagtcta
    48841 acttagaact cgtcactggt aaaccttgaa tagatacttg accgcttgtg accagtttat
    48901 ctccaagcaa acaatctaag agtgttgtct ttccggcacc atttggacca attaaggcaa
    48961 cacattcacc atcgttgatt tcaaaggaga tattccgcaa aatttccttg tcttttattt
    49021 tcttactcaa tttctcaact ttaaccaccg tcatgagact ctcctttcaa ccactccatt
    49081 cccataagga aaacgacgaa aatcataaat ccaaacccca aagcaccacg aatgaattgg
    49141 cgaagcaagg cttgatcaaa ccaatcagta aacatttcca ctaaccatac caagagtgac
    49201 aggccgataa agaaatagat gatccctctc ttcattcctc aaactccttt ttcacatctc
    49261 tgactaattt caaaccttct ctaacaagcc aagacatgat tccaaagcca gcaaagacct
    49321 tccaaggaaa atggtagaaa tcctcatcca atcccgaaaa catgagatag gtcataactc
    49381 ctgctactac taaacttact gcgataatca ttttatttct catctcttct tcccccattt
    49441 catactacaa ttatagtctt ttaaaatcag aggagacaga agcttctgtc actagaaaat
    49501 atgacaaatg tcataaaaaa ttctgttcaa aacaagcaag atacactata caataaaaca
    49561 caatcagaaa aatctaaggc aacttcctca aaagagatat caaacccaat tcacaccata
    49621 atgtaaacta atacttattt aaaatcaaaa agagtaaaaa tttttatcag acaaacacat
    49681 atatagtgta ttgaatctat aacagtaggc cttaaatact aaaatatttc tataaattaa
    49741 tttaactttc ctgatagaac tgttcatatc ttatttcaat tctctatatt atacgttgaa
    49801 ccaaaccctt ctattgcttt cttaaaaatt tataagagtt ataaaatctg ttaaatttca
    49861 atgtgtatac ctaaactacg gtatttattg aaaaaactgg agacaaaaag tatacgttgc
    49921 caaaatgaat tactgaaaat caaaaaagag aggaccaaac tgattccctc ttaatgtata
    49981 taatatctag ttttaaaaat acacactcac atatctctgt
//
LOCUS       DBERDS010000010        49314 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.010, whole genome shotgun sequence.
ACCESSION   DBERDS010000010 DBERDS010000000
VERSION     DBERDS010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 49314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.010"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..333
                     /locus_tag="ACL73E_000655"
     CDS             <1..333
                     /locus_tag="ACL73E_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGS0800671.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="ACL73E_000656"
     CDS             500..1198
                     /locus_tag="ACL73E_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0800672.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="ACL73E_000657"
     CDS             1195..2247
                     /locus_tag="ACL73E_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0800673.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL73E_000658"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL73E_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGS0800674.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3238..3393
                     /locus_tag="ACL73E_000659"
                     /pseudo
     CDS             3238..3393
                     /locus_tag="ACL73E_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            complement(3497..3634)
                     /locus_tag="ACL73E_000660"
                     /pseudo
     CDS             complement(3497..3634)
                     /locus_tag="ACL73E_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3714..3974
                     /locus_tag="ACL73E_000661"
     CDS             3714..3974
                     /locus_tag="ACL73E_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800675.1"
                     /translation="MTGVSNPTTDSARLVLADSKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            3928..4149
                     /locus_tag="ACL73E_000662"
     CDS             3928..4149
                     /locus_tag="ACL73E_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800676.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            4468..5397
                     /locus_tag="ACL73E_000663"
     CDS             4468..5397
                     /locus_tag="ACL73E_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800677.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5411..6334
                     /locus_tag="ACL73E_000664"
     CDS             5411..6334
                     /locus_tag="ACL73E_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0800678.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6438..7913
                     /locus_tag="ACL73E_000665"
     CDS             6438..7913
                     /locus_tag="ACL73E_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0800679.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKSVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8185..9171
                     /locus_tag="ACL73E_000666"
     CDS             8185..9171
                     /locus_tag="ACL73E_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGS0800680.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9293..10144
                     /locus_tag="ACL73E_000667"
     CDS             9293..10144
                     /locus_tag="ACL73E_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGS0800681.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDVPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILV
                     QDFKTLA"
     gene            complement(10225..11289)
                     /locus_tag="ACL73E_000668"
     CDS             complement(10225..11289)
                     /locus_tag="ACL73E_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGS0800682.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEERAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIEAPEDSEARTGIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11352..12263)
                     /locus_tag="ACL73E_000669"
     CDS             complement(11352..12263)
                     /locus_tag="ACL73E_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGS0800683.1"
                     /translation="MRKWTKGFLIFGVATTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSANHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12256..12848)
                     /locus_tag="ACL73E_000670"
                     /pseudo
     CDS             complement(12256..12848)
                     /locus_tag="ACL73E_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
     gene            complement(12835..13161)
                     /locus_tag="ACL73E_000671"
     CDS             complement(12835..13161)
                     /locus_tag="ACL73E_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS0800684.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13300..14466)
                     /locus_tag="ACL73E_000672"
     CDS             complement(13300..14466)
                     /locus_tag="ACL73E_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGS0800685.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            14524..15684
                     /locus_tag="ACL73E_000673"
     CDS             14524..15684
                     /locus_tag="ACL73E_000673"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0800686.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNMLQ"
     gene            15723..17573
                     /locus_tag="ACL73E_000674"
     CDS             15723..17573
                     /locus_tag="ACL73E_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGS0800687.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(17831..18463)
                     /locus_tag="ACL73E_000675"
     CDS             complement(17831..18463)
                     /locus_tag="ACL73E_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0800688.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18485..19357)
                     /gene="sdaAA"
                     /locus_tag="ACL73E_000676"
     CDS             complement(18485..19357)
                     /gene="sdaAA"
                     /locus_tag="ACL73E_000676"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGS0800689.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19366..20037)
                     /gene="sdaAB"
                     /locus_tag="ACL73E_000677"
     CDS             complement(19366..20037)
                     /gene="sdaAB"
                     /locus_tag="ACL73E_000677"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGS0800690.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDDAIEEIRKIPHLHN
                     VNFFK"
     gene            20279..20866
                     /locus_tag="ACL73E_000678"
     CDS             20279..20866
                     /locus_tag="ACL73E_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS0800691.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(20918..21244)
                     /locus_tag="ACL73E_000679"
                     /pseudo
     CDS             complement(20918..21244)
                     /locus_tag="ACL73E_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            21997..22377
                     /locus_tag="ACL73E_000680"
     CDS             21997..22377
                     /locus_tag="ACL73E_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HGS0800692.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVDL
                     AIYSGGATIYSADAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGVDWADGSLDGYIFA"
     gene            22379..22585
                     /locus_tag="ACL73E_000681"
     CDS             22379..22585
                     /locus_tag="ACL73E_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800693.1"
                     /translation="MKHFFAGIGEINFVSYLLYICVGIAPFFHVYIIGSEMNFVKIVL
                     SILGIIFVCILTIARIYRTFFYKE"
     gene            complement(22778..23641)
                     /locus_tag="ACL73E_000682"
     CDS             complement(22778..23641)
                     /locus_tag="ACL73E_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0800694.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRRIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            24107..24445
                     /locus_tag="ACL73E_000683"
     CDS             24107..24445
                     /locus_tag="ACL73E_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGS0800695.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKIKGTRITK"
     gene            24540..24917
                     /locus_tag="ACL73E_000684"
     CDS             24540..24917
                     /locus_tag="ACL73E_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800696.1"
                     /translation="MSPGTFIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLALIF
                     LIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVYIFLGYVLVIQKDVYLFSIL
                     IIFSNFSVPFIREKEYELFKNKK"
     gene            25071..25283
                     /locus_tag="ACL73E_000685"
     CDS             25071..25283
                     /locus_tag="ACL73E_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800697.1"
                     /translation="MMIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            25699..26061
                     /locus_tag="ACL73E_000686"
     CDS             25699..26061
                     /locus_tag="ACL73E_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS0800698.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGGVGCNWWNKRDNIAAAAVSGG
                     MSVYQTYAIKKLIANRGMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGA
                     IAYGLDIVDGKFDGYLWA"
     gene            26042..26287
                     /locus_tag="ACL73E_000687"
     CDS             26042..26287
                     /locus_tag="ACL73E_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800699.1"
                     /translation="MDIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSTSPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            26444..27502
                     /locus_tag="ACL73E_000688"
     CDS             26444..27502
                     /locus_tag="ACL73E_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800700.1"
                     /translation="MKDDQKYLLAGFYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFMFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSKVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            27817..28794
                     /locus_tag="ACL73E_000689"
     CDS             27817..28794
                     /locus_tag="ACL73E_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800701.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            29171..29545
                     /locus_tag="ACL73E_000690"
     CDS             29171..29545
                     /locus_tag="ACL73E_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGS0800702.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            29552..29734
                     /locus_tag="ACL73E_000691"
     CDS             29552..29734
                     /locus_tag="ACL73E_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800703.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWINVV
                     FLILIIAMMIYPKLRK"
     gene            29753..30655
                     /locus_tag="ACL73E_000692"
     CDS             29753..30655
                     /locus_tag="ACL73E_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800704.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            30711..31064
                     /locus_tag="ACL73E_000693"
     CDS             30711..31064
                     /locus_tag="ACL73E_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGS0800705.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            31061..31789
                     /locus_tag="ACL73E_000694"
     CDS             31061..31789
                     /locus_tag="ACL73E_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800706.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDTKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            32268..32474
                     /locus_tag="ACL73E_000695"
     CDS             32268..32474
                     /locus_tag="ACL73E_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800707.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFFYKE"
     gene            32890..33429
                     /locus_tag="ACL73E_000696"
     CDS             32890..33429
                     /locus_tag="ACL73E_000696"
                     /inference="COORDINATES: protein motif:HMM:NF037419.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HGS0800708.1"
                     /translation="MLFYFEKIWSLSLKLLDCILDYQERFNGKTCQVSTNYKYLEIFK
                     VNFCLTDLHHLFGLHKITRDYASQTKPAIQTGVFILEDFRNILLYNDVIERISLYEFI
                     SDIFYSKITSCCIVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFT
                     SAKKYAKVRKTDVKEMKWL"
     gene            33714..35621
                     /gene="pspA"
                     /locus_tag="ACL73E_000697"
     CDS             33714..35621
                     /gene="pspA"
                     /locus_tag="ACL73E_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HGS0800709.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSSPTFVRAEEAPVASQSKAEK
                     DYDAAKKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEKKAAAVKKIDEEHQAAN
                     LKSQQALVEFLAAQREGNPKKKKAAQAKLEEAEKAEKEKKKEFDKAQAVVVPEATELA
                     ETKKKADEAKVKEPELTKKLEEAKAKSEEAEKKATEAKQKVDAEHAKEVVPQAKIAEL
                     ENEVQKLEKDLKEIDESDSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDELDAE
                     IAKLEKNVEDFKNSNGEQAEQYRAAAEEDLAAKQAELEKTEADLKKAVNEPEKPAPAP
                     ETPAPEAPAEQPKPAPAPQPAPAPKPEKPAEQPKAEKTDDQQAEEDYARRSEEEYNRL
                     TQQQPPKAEKPAPAPKPEQPAPAPKIGWKQENGMWYFYNTDGSMATGWLQNNGSWYYL
                     NANGSMVTGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGAMATGWLQNNDSWY
                     YLNASGAMATGWAKVNGSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWVKVNGS
                     WYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVD
                     GYKVNANGEWV"
     gene            36022..37143
                     /gene="mnmA"
                     /locus_tag="ACL73E_000698"
     CDS             36022..37143
                     /gene="mnmA"
                     /locus_tag="ACL73E_000698"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGS0800710.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            37284..37739
                     /locus_tag="ACL73E_000699"
     CDS             37284..37739
                     /locus_tag="ACL73E_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0800711.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEYAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            37749..39662
                     /gene="mnmG"
                     /locus_tag="ACL73E_000700"
     CDS             37749..39662
                     /gene="mnmG"
                     /locus_tag="ACL73E_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGS0800712.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMINEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(39996..41675)
                     /locus_tag="ACL73E_000701"
     CDS             complement(39996..41675)
                     /locus_tag="ACL73E_000701"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGS0800713.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAIKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(41677..41910)
                     /locus_tag="ACL73E_000702"
     CDS             complement(41677..41910)
                     /locus_tag="ACL73E_000702"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGS0800714.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            42190..42405
                     /locus_tag="ACL73E_000703"
                     /pseudo
     CDS             42190..42405
                     /locus_tag="ACL73E_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(42728..42880)
                     /gene="cibB"
                     /locus_tag="ACL73E_000704"
     CDS             complement(42728..42880)
                     /gene="cibB"
                     /locus_tag="ACL73E_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGS0800715.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(42883..43069)
                     /gene="cibA"
                     /locus_tag="ACL73E_000705"
                     /pseudo
     CDS             complement(42883..43069)
                     /gene="cibA"
                     /locus_tag="ACL73E_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
     gene            43246..43929
                     /gene="tsaB"
                     /locus_tag="ACL73E_000706"
     CDS             43246..43929
                     /gene="tsaB"
                     /locus_tag="ACL73E_000706"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGS0800716.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVAPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEAESLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            43926..44363
                     /gene="rimI"
                     /locus_tag="ACL73E_000707"
     CDS             43926..44363
                     /gene="rimI"
                     /locus_tag="ACL73E_000707"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGS0800717.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            44353..45363
                     /gene="tsaD"
                     /locus_tag="ACL73E_000708"
     CDS             44353..45363
                     /gene="tsaD"
                     /locus_tag="ACL73E_000708"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGS0800718.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGESYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEVTDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(45403..46708)
                     /locus_tag="ACL73E_000709"
                     /pseudo
     CDS             complement(45403..46708)
                     /locus_tag="ACL73E_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(47044..47326)
                     /locus_tag="ACL73E_000710"
                     /pseudo
     CDS             complement(47044..47326)
                     /locus_tag="ACL73E_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(47463..47753)
                     /locus_tag="ACL73E_000711"
                     /pseudo
     CDS             complement(47463..47753)
                     /locus_tag="ACL73E_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            47996..48862
                     /locus_tag="ACL73E_000712"
     CDS             47996..48862
                     /locus_tag="ACL73E_000712"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0800719.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICYLKCRD
                     NFRLLGEIYPVL"
     gene            48916..49200
                     /locus_tag="ACL73E_000713"
     CDS             48916..49200
                     /locus_tag="ACL73E_000713"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0800720.1"
                     /translation="MCVLESMSQGTPVLASNVGGLSEIIEHRVDGFLFEKEDVEGVCA
                     CANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYDELLEKSSHG"
     gene            49193..>49314
                     /locus_tag="ACL73E_000714"
     CDS             49193..>49314
                     /locus_tag="ACL73E_000714"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0800721.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQNYKNIEV"
BASE COUNT        15247 a         8496 c        10485 g        15086 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctggcgtga ctccgatgaa tcacaatcat gctacaggta ctacagatag catgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagactagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctgg ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaacgcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgccc agttgtcgca tgatattaag actcctatca cttcgatcca agcgacggta
     1621 gaagggattt tggatggtat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagaa atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 gctaagctgg agaaggacca gctttcaatc agtgtgaccg atgaagggca gggtattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgc ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaac
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaga
     2281 atagattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 acggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgc gtaactccag gtcaagtgat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaaattg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caagatgttg taatatttta
     3061 ttgaataaga caggctttga ggccttgata ttaagcactt tgggacgttc tcccttagtg
     3121 cttttttgat ttctcttagt atccagctat aatcgtttag acataactag accgatatag
     3181 tccaaagtga tatagtaaaa tgaaccaaaa atagtacaca atgtggtata atcttttatg
     3241 gaatattcaa tagattttcg taaaaaagtt ctctcttatt gtgagcgaac aggtagtata
     3301 acagaagcat cacacgtttt ccaaatctca cgtaatacca tttatggctg gttaaagcta
     3361 aaagagaaaa caggagagct aaaccaccaa gtatagtgta ttgaatctat aacagtacac
     3421 cttggctgct aaaatatttc tataaattaa tttggctttc ctgatagagt tgttcacatc
     3481 ttatttcaaa tcactataaa agctctataa tctctttata agatttgccc atcagacgaa
     3541 atagaacgat ttgaaggcgt ttatgatatt tagctgtacg agagtctttt aaaagtgttt
     3601 tgatggtttg gatttcttct ttagttgatt tcatatcact gttatataat gctttttgat
     3661 tttagtctag tattagtaag cagactcaaa ccttagaaaa tcttttgaga tcattgacag
     3721 gtgtatcgaa tcctaccaca gattcagcac gtctggtttt ggcagactct aagaaagctt
     3781 ttgcagatga tagtttgata gagcaaggtt tacgtgatat cttgcaaaca gtcaaagatg
     3841 ccattgcttc cctagagtcc attaaggaaa gccagtcagc aactaaggat ggaggacaaa
     3901 cagcgggcaa agaaacagca ggagaagatg agtctgcaaa tcaaactcaa gaaattagcc
     3961 aaggaattaa gtaaacttct taaagactca aaccttgaaa cagtagataa ggatgtcctt
     4021 gaaaactctc aagaagaact tcaaaaagca gttttgttct tggcagatga aaaaggctct
     4081 gagcatactg cagcagagtt gattgataat cttaaagagg ttattgctaa gttgaaagca
     4141 aacgcctaat aacatattaa aaatctccag attaggaact atcgctgagt tccctagtct
     4201 ggagattttt cagtataccc cgttgttgga tgcttataac agagtgacgc catcactggg
     4261 ctaatagaga taaaataaac aattgattta ggacatttgt ttgatagtgg tgataaagtt
     4321 ttaaatctgc tacataattt gtggagtttt ttctataatt aggagtttaa cctaacctgc
     4381 aaataggagt atactaataa tgtaatcgtt atcaaaagtc taaaaaagaa tttttagatg
     4441 gatatcaaaa taaaaaggga ggaaattatg aaaaagtttt caaaaacatt gagagacaac
     4501 tggatctttc tcttgatggt tttgccaggg gcactctggt tgattctatt cttttacatt
     4561 ccagtatttg ggaacgtggt tgccttcaaa gactaccaca tgaccagtaa tggtttcata
     4621 gatagtatca taaatagtaa atgggtcgga ctcgataatt tcagattctt atttagttca
     4681 agagacgcct ttattatcac acgaaatact gtcctctaca atcttggctt tatctttcta
     4741 ggtttagttg tatctgtagg gattgccatt atcctcagcg agctccgttc taagagaatg
     4801 gtgaagattt ttcaaacttc tatgttgttc ccttacttct tgtcttgggt tatcatcagt
     4861 ttctttacag atgccttcct aaatattgat aaaggggtgt tcaatcatct attggaaagt
     4921 cttggtctca aagaagtcaa tttctacgct gacctgggca tctggcccta tctcctactt
     4981 ttcctaggta tttggaaagg ctttggatat agcagtgtca tgtactatgc gacgatcatg
     5041 ggaattgatc caacctacta cgaagcagcg acagtggacg gagctagcaa gtggcaacgt
     5101 attcgcaatg taaccattcc tcagttgact ccgcttgtaa ctgtattgac catccttgca
     5161 gtcggaaata tcttccgcgc agacttcggt ctcttctatc aaatcccaca caatgctggt
     5221 cagctttaca atgtaaccaa cgttttggac gtatatgtct ttaatggttt gactcagaca
     5281 gcagatatcg gtatggctgc agcagccggt ctttaccaat ccgttgttgg tttgattctg
     5341 gttatcctat caaacttgct tgcaagacga gtcgatccaa actcagcttt gttctagaaa
     5401 ggaggagaat atggcaaaaa agaaaattaa aaaagaaaaa attgataatg tcggcattca
     5461 ctccttcagt aagaaagcag atatcttctt cagtatcatt tcgggtttga ttgccctctc
     5521 ttgtatccta ccttttgtat tcgttatcat tatttcagtg acagacgaga aaagcctcct
     5581 ccaatacggc tatagcttct tcccatccca atttggctta gacggttttg agtttttggc
     5641 acagtttaag gataaaatcc tacaagccct cttcatctct gtctttgtaa ccgtagttgg
     5701 gacattgaca aatgtcttta tcacaacaac ctatgcctac gctatttcac ggacaacctt
     5761 taagtatcgc agatttttta ccatcttcgt ccttctcagt atgttgttca acgctggttt
     5821 ggtaccaggt tatatcatgg tgacccgtgt acttcagctt ggtgacactg tttgggcttt
     5881 gattgttcca atgcttctct caccattcaa tatcatcttg atgcgttctt ttttcaagaa
     5941 gaccattcca gaagccattc tcgaatcggc tcgtatcgat ggtgccagtg aggctcggat
     6001 tttcttccaa atctgtttgc cattgtcact accaggtatc gcaaccatca cgcttttgac
     6061 agctcttggt ttctggaatg actggttcaa cgcccttctt tacatcaaga gtgataactt
     6121 gtatccattg caatatttgc tcatgcaaat ccaacaaaat atggactaca ttgccaaagc
     6181 ggtcggcttg actggtcaac tgggagttgc tctaccgaaa gaaacaggtc gtatggccat
     6241 ggttgtggta gcaacccttc caatcgcgat tttgtatcca ttcttccaac gctactttgt
     6301 aaaaggtttg actatcggtg gtgtgaaaga atagtgctta ttgaaaaaga acatttctca
     6361 tttccaaact tcccttgcgt gaagttaaga tcattacatt gtttataagt ttaaaaataa
     6421 aaaaaggagt ttttatcatg aaaaattgga aaaaatatgc ttttgcatct gctagtgtag
     6481 tcgctttggc tgcaggtctt gctgcttgtg gcaacttgac aggtaacagc aaaaaagctg
     6541 ctgattcagg tgacaaatct gttatcaaaa tgtaccaaat cggtgacaaa ccagataact
     6601 tggatgaatt gttagcaaat gccaacaaaa tcatcgaaga aaaagttggt gccaaattgg
     6661 atatccaata ccttggctgg ggtgactatg gtaagaaaat gtcagttatc acatcatctg
     6721 gtgaaaacta tgatatcgcc tttgcagata actatattgt aaatgctcaa aaaggtgctt
     6781 atgctgactt gacagaattg tacaaaaaag aaggtaaaga cctttacaag gcacttgatc
     6841 cagcttatat caagggtaat actgtaaatg gtaagattta cgctgtacca gttgcagcca
     6901 acgtagcatc atctcaaaac tttgccttca acggaactct ccttgccaaa tatggtatcg
     6961 atatttcagg tgttacttct tacgaaactc ttgagccagt cttgaaacaa atcaaagaaa
     7021 aagctccaga cgtagtacca tttgctattg gtaaagtttt catcccatct gataactttg
     7081 actacccagt agcaaacggg cttccattcg ttattgacct tgaaggcgat actactaaag
     7141 ttgtaaaccg ttacgaagtg cctcgtttca aagaacactt gaagactctt cacaaattct
     7201 atgaagctgg ctacattcca aaagacgtcg caacaagtga cacttcattt gaccttcaac
     7261 aagatacttg gttcgttcgt gaagaaacag taggaccagc tgactacggt aacagcttgc
     7321 tttcacgtgt tgccaacaaa gatatccaaa tcaaaccaat tactaacttc atcaagaaaa
     7381 accaaacaac acaagttgct aactttgtca tctcaaacaa ctctaagaac aaagaaaaat
     7441 caatggaaat cttgaacctc ttgaatacga acccagaact cttgaacggt cttgtttacg
     7501 gtccagaagg caagaactgg gaaaaaattg aaggtaaaga aaaccgtgtt cgcgttcttg
     7561 atggctacaa aggaaacact cacatgggtg gatggaacac tggtaacaac tggatccttt
     7621 acatcaacga aaacgttaca gaccaacaaa tcgaaaattc taagaaagaa ttggcagaag
     7681 ctaaagaatc tccagcgctt ggatttatct tcaatactga caatgtgaaa tctgaaatct
     7741 cagctattgc taacacaatg caacaatttg atacagctat caacactggt actgtagacc
     7801 cagataaagc gattccagaa ttgatggaaa aattgaaatc tgaaggtgcc tacgaaaaag
     7861 tattgaacga aatgcaaaaa caatacgatg aattcttgaa aaacaaaaaa taatcagcta
     7921 aattgatttc gtgtattcat tcctaactcc taaaataaga atcactgctt tcctcaggtt
     7981 ggtctggggg agacagtggt ttttttggca caaggatata gatatccatg ttttctcttg
     8041 tccttatttt aaccattcag gaaatttcga gacccctcta caatttccag tcaaataaat
     8101 tgcattcgtt ttctcaagca ggtatactag tgtagataaa taaaaaattt agaaaattta
     8161 agaatagaaa agagaacaaa tcttatggca aaagatattc gtgtcttact ttactacctt
     8221 tatactccaa ttgaaaatgc agagcaattt gctgcagacc acttggcttt ctgtaaatca
     8281 atcggtctta aaggacgtat cctagtcgct gacgagggaa ttaacggaac agtttcaggt
     8341 gactatgaaa caactcaaaa atacatggac tacgttcaca gccttccagg aatggaagaa
     8401 ctctggttca agattgacga agaaagtgaa caagccttca agaagatgtt tgttcgctac
     8461 aagaaagaaa ttgtccacct tggtttggaa gacaacgact ttgacaatga catcaaccca
     8521 cttgaaacaa caggtgctta cttgtctcca aaagagttca aagaagcgct tcttgataaa
     8581 gataccgttg tccttgacac acgtaatgat tatgagtatg acctaggaca tttccgtggg
     8641 gctattcgcc cagatattcg caacttccgt gagttaccac aatgggtccg tgataacaag
     8701 gaaaaattca tggacaagcg tgtcgtggtt tactgtacag gtggcgttcg ctgtgagaaa
     8761 ttctcaggct ggatggttcg tgaaggttac aaagatgtcg gccaattgca cggaggaatc
     8821 gcaacttacg gtaaagaccc agaagttcaa ggtgagcttt gggatgggaa aatgtacgtc
     8881 tttgacgagc gtattgccgt tgatgtcaac catgtcaacc caactatcgt agggaaagac
     8941 tggtttgatg gaacaccatg tgaacgttat gtcaactgtg gaaatccctt ctgtaaccgt
     9001 cgtatcttga catcagaaga aaatgaagac aagtaccttc gtggatgctc acacgagtgc
     9061 cgtgttcacc cacgtaaccg ctatgtttca aaaaatgaat tgacacaagc tgaagtgatc
     9121 gagcgcctag ccgctatcgg tgaaagcttg gatcaagcag ctactgtata agatcaaaca
     9181 gtcctcaggg gctgtttttc tatgctttgt actcaaaaat ctaaagtttg tttttgtatc
     9241 tttcagaaaa ataaggtata ctgtatgtaa acgatttcaa aggagtccag ttatggcgaa
     9301 aacatttttt attccaaata aacagagcat tttaggagaa caagagattt tgaatgccaa
     9361 gtcgatcttg gccttgctag acggtttgga gtcacatagc tatgatgtag tctatctccg
     9421 tcagcctctt aatcgtctcg aatatatcga gtgtgcgata gtggggcaat cacaatttct
     9481 ctttaaggtc agttatgctg atggtcaaaa ggcttatcgt gtcgatgttc ctgacctact
     9541 aacaaagaca gactggcaga ttatcaagtc atttttagat gctttgcttg cttatacagg
     9601 gactgatatt gaaggactag atggttttga ttttgaagct tatttccaag caagtattca
     9661 agcctatcta gcagaccctg tagctcgttt tacgatttgc caaggaattt ttaatcctat
     9721 tttctttagt cgtgagaact tgaaaagctt tttagaggca gatggcttgg ctcagtttga
     9781 agcgcgtgtg cgtgcggttc aagagacaga tgcctacttt gcgagagttt ccttctatca
     9841 ggatggagaa ggaaaagtgc atggcgttta ccatctagct caaggagtca agacagtttt
     9901 accgagagaa ccgtttgttc ctgcagccta tattgagcaa ttggtggata aggaagtcca
     9961 gtgggagatt gacttggttc aaatcacagg agacggctct aaaccagaag actatgaatc
    10021 catagctcgc ttggactatg caaaattctt agaggtgtta cccccatctt tttaccacca
    10081 gctagacgcc aatcaaatag aaatacaacc catcctagta caagatttta aaacattagc
    10141 ataagaaaag taaagcagaa gcaggtcaat cgacttgctt ttttgacata gaaaaaatcc
    10201 tgccaagaat gacaggattg aattttaaag aaaggccaag atacgaagat aatctccaat
    10261 cagtgccact tcagctacaa agaagaggag gataataact ccgttcacaa ggacagacaa
    10321 gaataattga tagaaggagt cggtttcact tgcttgactt ggtcttgtaa tgatatggag
    10381 actggcaagc agaatgattc caatgctaat cacacacaag agggctgtaa atcgtaggct
    10441 atcaaagaaa gcaaagaaac tagcaatagc agtgaggaag attggaattg ccaagagttg
    10501 actatattgt tggagaacct tgtctagcgt ccagtccttt tcctggtgga taaatcgtct
    10561 cacaacgaaa ctacccaaga ggaatgaaaa gaagaagagt gttgtcgcta ctaggataga
    10621 gacgatagaa aaaagagtta aaggagctag ctgctcaggg aagcgactgt taatgcttgc
    10681 tatatgtcca tagtaagcat gtttgatgtg atagatacta aagaaaaagg aagatgcaga
    10741 aaacagaatg agcaagagaa aggctgtgta actgtgtgtg atacttgttt ccaacttact
    10801 tgtaggagat ttgatcgctt ccactagcca agaccaaaaa tcaagcactt gctctttcca
    10861 tttatcccta gattttggag cttggtcggg gatataagga ctttctaaag atttactgat
    10921 aagaagtggc tctttcgtgg ttgctttttg ctgaggaaga gcttcttggc tctcttcagc
    10981 tatagtgact ttttctgttt ctttagaaag gtctggctct tcttcagtag aattagatgc
    11041 cttcttttct tctattcctg ttctcgcttc actgtcttca ggagcttcaa ttttctcttc
    11101 ttgttggctt tccagttcga cttcagcttg agagacttcc tcctctactt gagtattttt
    11161 tccaattggt gtatcgagat tggctatcgt ttcttcagcc ttgtctgcaa cctcttgagc
    11221 tcgctcttca ggcttgttct tgcttgttgt ttttacaaaa tcattacttt caaaccattc
    11281 ttgtttcatg gtagaacctc ctttttagtt agataaatat gtttccatag tagcaaatgt
    11341 aagcgttttt gtcaacgtct gcttggtgtg gatattagat caatattatc atcagatctc
    11401 gcaatgagtt gatccttgac atcggttttt tcagttttgt aagggttgct taattccgta
    11461 cctcttgatt caggcttttc tcttgtgaat tggaagatag aaccatagtt gcttgagatg
    11521 tcccagttaa ttcgttggct ttctttctgg tctaggatga ttctgagata atctttggca
    11581 gtcagttcaa ccttgccatg gacttggata ttttcagcgt ggaagtgatt ctctgttgac
    11641 tctagctgac tatctgtaag aactgtatca aagatattaa cgatattggg cgttgtgagt
    11701 ttactgtttt tgatacgact tccttcaatt cggaggatat agctgtttgt attgagggtc
    11761 gcattttcaa ggctagcatt tatgatggtg gtttgtccgc gattggctga gatgttgatc
    11821 ccttttagag ttctcccttt tggtagctgg agaataactt cttcaaaacg actagagtag
    11881 ctacttgcga tatgaagaat cccaccaatt ccagaagaga gaaacggagt ttcagacagt
    11941 ttcttatcag tgagactcag agttctatcg ttttgatttg tgataagatc atggttagca
    12001 gaaagagatg gatggtaaga aatgtggatt tgatcatcga aagagtctgt gatggtgagc
    12061 gcgtgttggt ggagagtaat ttctaggttt tcgacttcct tgccaaaggt tagcttttcc
    12121 gtacggctat catagacagg ttctttggac atggaaagta ggctcttaat cccgtcagat
    12181 tggataccta caaaaagcag gataaagccg ataacggtag tcgccacacc aaagatgaga
    12241 aatccttttg tccatttacg catgctgatt acctctcttt ccttttttaa gaacaaattg
    12301 taccagacga acaatgagta gaccgaagaa gcgagttaca taggaaatgc caagtaaaac
    12361 tagcgaagaa gcaccgatag ccagtaaacc agaaccaaaa atcaagataa aggctgattt
    12421 ggcttgggcg aggacagtga aactttcaac taaaaatagg aatccgccga tgatacccag
    12481 tatggaaact gcaaagaaag ccagaatgac agtcaaagcg gctacaagaa ttgcgaacag
    12541 ggtcacgagg atggcaattc ccagaggaat gccgataggt gctgcaagga gggctaacaa
    12601 ggcgatatgt aaaatttgtc ggttattttt ttgagcgggt gcttcattga ttttttatcg
    12661 agaagattgg atagaacttc gtgggccgct tctttgggag ttcccaaact agcgatgagt
    12721 tcttcttctc cttcgactcc agcatcgtca aagagctctc tgaaatagtc catggcttcg
    12781 atacggtcag cttcaggtag tttcttgaga tagagttcta gctgagtcag gtattcagtt
    12841 cttgtcatgg cggatactcc cttctatgat gccattgatg gtgtctgtat agagtgccca
    12901 ttcatctttt agggtcaaga gctgctctat accaccgttt gtcaaggagt agtatttgcg
    12961 catgcgacct tggaactctc tagaataggt tgtcagaaag ctattgcctt ccaatttttt
    13021 gagaatggga tagagtgtgg attctttgat attagcgatc agcttaatgg tttggctaat
    13081 ctcataacca taagaatcac cctgctccag tacagccaag atgagaaatt caatcaaggc
    13141 agaggatgtt ggaaagtaca tgggaaacct ccttttctaa tgtgtaagat ttttatatat
    13201 aatttttcta cacatacatt gtacatctaa aagaaagccc tgtcaagaga aatgtgtaaa
    13261 atttttatat ataaaaaact tctagctaaa actagaagtt taaaggatct tatccgctct
    13321 gtccactgta aagagggcca cagtcatcag gatatcgatg agcaagaggg cagctacaga
    13381 tggtacccaa gagtggaaca ggtcaaaact gtaaccaaag agggttggcc caaaggctgc
    13441 taggatatag cctcctgttt gagataggcc ggacaattgg gctgtctttt caggggcgct
    13501 tgtcttgagt gaaaagttga ccatgagata agggaagagg gcactggttg cggttccgat
    13561 gaggagatgg atggcaagcc agtaaatgaa attattgatt gggaaaaaga gcatggaaat
    13621 gccgaccaca ccagctagtg aaaccagagt gagcatgagc tgacggttgc gagtagataa
    13681 actggttgtc aggcttggga tggtcattga aaaaggaatg ctaatcagag ataagataga
    13741 agtcagcaag ccagcttcgt gactggatag acctgcatgg atagacatgg taggtaacca
    13801 ggtcatgacg gtgtaaaaga tcaaggattg aaaacctgaa aagataataa ttgcccaaac
    13861 ctgtttatta cgcatgacct ttatttgact tttttgtttg gtttgtggag ctagtctatg
    13921 attatagcgg tgatttggga gccagaccaa aaaagttgct agacagagta acgtgaggag
    13981 aaggataagt cctttccaag aactggcttg tgtaatgggc acagctagat aggaagccag
    14041 agccgttgca atccccatag acgttacata taaggtggtc agaaaaccaa ttttctttgg
    14101 ttgattggct tggataagac taggaagcag gacattgatg actgcgacac ttgccccaac
    14161 catcaaggtt cctagataga gcaggggcag attgattagt cgaataagtg agccgatggt
    14221 caagaagaag aggctgtagg tgaagagatg ctccaagccg attttctgag ccagttgggt
    14281 agaaaatggt gaaaagaggg taaacataag gagaggcagg ctggtcaaga caccaagcga
    14341 actaacttct acctccagac cttgcgaaat atttcccaaa ataatgggta aaacagtaaa
    14401 aggagttcgc aaggaaacac caatcaggat aatacctgga acaaaaaaga gtgattgctt
    14461 tttcatataa tacctcttct agctgatttt aataacagct tattttaagg ctttttcact
    14521 ataatgtcaa gtaaggtttc tggctttcaa gataaaaatg ggaaagtctt gaaaattatg
    14581 atagaatggt ggaaggaaaa attcaggaga gtagtagtga ctcaaaatgt tgaaagtctt
    14641 ctcgtatcca ttgtaatcag tgcatacaat gaagaaaaat atctgcctgg tctaattgaa
    14701 gacttaaaaa atcaaaccta tcctaaagag aatattgaaa ttctatttat aaatgctatg
    14761 tccacagatg ggaccacagc tatcattcag caatttataa aggaagatac agagtttaac
    14821 tcaattagat tgtataacaa tcctaagaaa aatcaagcta gtggttttaa cctgggagtt
    14881 aaacattctg taggggacct tattttaaaa attgatgctc attcaaaagt tactgagact
    14941 tttgtaatga acaatgtggc tattattcaa caaggtgaat ttgtctgtgg ggggcctaga
    15001 ccgacgattg tcgaaggaaa aggaaaatgg gcagagacct tgcatcttgt tgaggaaaat
    15061 atgtttggca gtagcattgc caattatcga aatagttctg aggatagata tgtttcttct
    15121 atttttcatg gaatgtataa acgagaggtt ttccagaagg ttggtttagt aaatgagcaa
    15181 cttggccgaa ctgaagataa tgatattcat tatagaattc gagaatatgg atataaaatc
    15241 cgctatagcc caagtattct atcttatcag tatattcgac caacattcaa gaaaatgctg
    15301 catcaaaagt atttaaatgg tttgtggatt ggcttgacaa gtcatgttca gtttaagtgt
    15361 ttatcattat ttcactatgt tccttgttta tttgttttga gtcttgtgtt tagtctagca
    15421 ttgttaccga tcacattcgt attcataact ttactattag gtgcctattt tctacttttg
    15481 tcactactca ctttgctgac tttattaaaa cataaaaatg gatttctaat tgtgatgccc
    15541 tttcttttat tttccattca ctttgcttat ggctttggga cgattgtagg tttaattaga
    15601 ggatttaaat ggaagaagga gtacaaggga acaataattt atttggataa aataagccaa
    15661 ataaatcaaa atatgctaca ataacaatat agtaaaactc ttttaaggag gagtagattt
    15721 ctatgaataa aaaactaaca gattatgtga ttgatctggt ggaaatttta aataaacaac
    15781 aaaagcaggt tttctgggga atatttgata ttttcagtat ggtggtttcc ataattgtat
    15841 cttatatttt attttatggg ctgattaatc cagcacctgt tgactacatt atctatacga
    15901 gtttggcctt cctgttctat caattgatga ttggtttttg gggattgaac gcgagcatta
    15961 gtcgttacag caagattacg gatttcatga aaatcttttt tggtgtgact gctagcagtg
    16021 tcttgtcata tagtatctgt tatgccttct tgccactctt ctccatccgt ttcatcattc
    16081 tctttatctt gttgagtacc ttcttgattt tattgccacg gattacttgg cagttaatct
    16141 actccagacg caaaaaaggt agtggtgatg gagaacaccg tcggaccttc ttgattggtg
    16201 ccggtgatgg tggggctctc tttatggata gttaccaaca tccaaccagt gaattagaac
    16261 tggtcggtat tttggataag gattctaaga aaaagggtca aaaacttggt ggtattcctg
    16321 ttttgggctc ttatgacaat ctgcctgaat tagccaaacg ccatcaaatc gagcgtgtca
    16381 tcgttgcgat tccgtcgctg gatccgtcag aatatgagcg tatcttgcag atgtgtaata
    16441 agctgggtgt caaatgttac aagatgccta aggttgaaac tgttgttcag ggccttcacc
    16501 aagcaggtac tggcttccaa aaaattgata ttacggacct tttgggtcgt caggaaatcc
    16561 gtcttgacga atcgcgtctg ggtgcagaac tgacaggtaa gaccatctta gtcacaggag
    16621 ctggaggttc aatcggttct gaaatctgtc gtcaagttag tcgcttcaat cctgaacgca
    16681 ttgtcttgct cggtcatggg gaaaactcaa tctaccttgt ttatcatgaa ttgattcgta
    16741 agttccaagg gattgattat gtacctgtga ttgcggacat tcaagactat gatcgtttgt
    16801 tgcaagtctt tgagcagtac aaacctgcta ttgtttatca tgcggcagcc cacaagcatg
    16861 ttcctatgat ggagcgcaat ccaaaagaag ccttcaaaaa caatatccgt ggaacttaca
    16921 atgttgctaa ggctgttgat gaagctaaag tgtctaagat ggttatgatt tcgacagata
    16981 aggcagttaa tccaccaaat gttatgggag caaccaagcg cgtggcggag ttgattgtca
    17041 ctggctttaa ccaacgtagc caatcaacct actgtgcagt tcgttttggg aatgttcttg
    17101 gtagccgtgg tagtgtcatt ccagtctttg aacgtcagat tgctgaaggt gggcctgtaa
    17161 cggtgacaga cttccgcatg acccgttact ttatgaccat tccagaagct agccgtctgg
    17221 ttatccatgc tggtgcttat gccaaagatg gggaagtctt tatccttgat atgggcaaac
    17281 cagtcaagat ttatgacttg gccaagaaga tggtgcttct aagtggccac actgaaagtg
    17341 aaattccaat cgttgaagtt ggaatccgcc caggtgaaaa actctacgaa gaactcttgg
    17401 tatcaaccga acttgttgat aatcaagtta tggataagat tttcgttggt aaggttaatg
    17461 tcatgccttt agaatccatc aatcaaaaga ttggagagtt ccgcactctc agtggagatg
    17521 agttgaagca agctattatc gcctttgcta atcaaacaac ccacattgaa taaaaaagaa
    17581 aaacgcatag tatcaagtta cacaaccttg gtaatatgcg ttttattatg tagagactta
    17641 tactcttcga aaatctcttc aaaccacgtc aacgtcgcct tgccgtatat ggttactgac
    17701 ttcgtcagtt ctatccacaa ccttaaaaca gtgtttagag cagcccgcag ctagtttcct
    17761 agtttgctct ttgattttca ttgagtatta cttcattttc ttctgaaatg gaattgttac
    17821 ccagtctatg ctattgaaaa tatgccaaaa cttctaaggg tttgtgagcg atataatcag
    17881 gttgatagtt tagtagatct gcttgctctc caaatcccca agtgacggcc aatttctgaa
    17941 tacctgtttc tcgagctccc agcatatcaa acttggtatc tccgatgatg atggcttgtt
    18001 ctggtgctag ttgatgtgtc tgtaaggctt ggtgaatgac atctgcctta tggggtgctt
    18061 cagggctaga accataaata ccatcaaaga aatgatggat ttccaagttt ttggccatgt
    18121 cttgagcagt agatgtattc tttgtcgtgg tgatgtagag tggataactg ctcgataact
    18181 cctcaagcaa gtctataatc tgaggaaaga gttgagcttc atagatgcct tttgccttat
    18241 agtaagaacg atatatctgc atggcttcag aaatttggtc tttggacagg caggtcgcaa
    18301 aactactttc gagaggtggt cccataaaac cacgaatagt tttggcatca gggctaggca
    18361 cccccagctc tttaaaggta taggtaaagg cattgtgaat cccgatagaa ctatcaacga
    18421 gggttccatc caaatcgaaa aaaatcgctg tgatagaggt catggtttct cctatttgat
    18481 aagcttattc tccgaaaatc tctttttgga ggcgacgacc agtaggggtg gtagcgagtc
    18541 caccttcagc tgtttcacga aaggcagttg gcatgcttgc tcctacttgg tacatggcat
    18601 cgatcacttc atccacaggg attttagatt cgatacctgc caaggccatg tctgctgcga
    18661 tgaaagcaaa gctagctccc atggcattac gtttgacaca gggaacttcg accaaacctg
    18721 caacagggtc acagatgagg cctagcatat ttttaatgac aaaggcaata gcttgactgg
    18781 cctgataagg tgttccacct gcagccagag tcaaggcggc agcactcata gcagaggctg
    18841 aaccaacttc agcttgacac ccaccctcag cacctgagat ggaggcattg tttgcgatga
    18901 ctagtccaaa ggcaccagca gcaaagagga aatccaattg ttgctcgtgg ctgaggtcta
    18961 atttttcaat agcagcagtg agaacggaag ggagacaacc ggcacttcct gcggtaggag
    19021 tagcgcagac caagcccatt ttagcattgt gttcattgac tgcgatagca tttcgggcag
    19081 cagagagaat cgtgtaatct gataaagttt tttcgttttt gatgtagtga tccaatttgg
    19141 cagcatctcc acctgtcagg ccactacgag atttattttc attgaggcca agttggacag
    19201 aggctttcat aacttccaga ttgcgttcca tgagaaggaa gacttcttca cgttcgcgac
    19261 cggtcaattc aaactctgtt gtaatcatga gttctgcgac atttccttga aagtccagat
    19321 ctgcttgctc gaccaattct ttgatagaat aaaacatgct tcctcctatt taaagaaatt
    19381 gacattgtgg agatgaggga tttttcgaat ttcttcgata gcatcatcac agttgcgact
    19441 gtcaacttcg ataatcataa tggctttttc accagctttt tcacgagtga cattcatctg
    19501 ggcgatattg ataccatagc gggaaagcgc ctctgtaaca agggcaatca tacctggaat
    19561 atcttgatga acgatgatga tagtcggtgt attcatattg agagagacgg caaaaccatt
    19621 gagttcggtt acctgaatat ttcctccacc gatagaaata ccagtcacgc tgatggtctt
    19681 gtgggcattt ttaacagtaa ttttagtggt gttagggtga ggggcattgc tgtctttctg
    19741 aatggtccag acaatcttga taccacgctt gtgggcaatt tccagactat ttggaatttc
    19801 aggatcatct gtatccattc ccaaaatacc tgcaacaagg gctaggtctg ttccgtgacc
    19861 acgataggtc ttggcaaatg agttaaaaag ttggaattca acttctgtcg gagtatcatc
    19921 aaaaatggaa gagacaatct tcccaatacg aacagcacca gcggtatggc tactagatgg
    19981 gccaatcata actggtccga tgatatcaaa gacagattga aaacgaagtg atttcatcag
    20041 tttcccctta taaaaattct tatctctatt atatcaaaga atgaggggct tggctttaat
    20101 tgtggatgaa aacctttcta atacctcaaa tagcataaaa atagtatctt ttatgacaaa
    20161 aaacacctta tttagggaaa taaaaaataa ttttgtaata tttctacata aaagtgtcaa
    20221 gaaacggtaa tatttaaagg gtatgataga actatagaaa gaaggagaat tttcgaatat
    20281 gaaatcaata actaaaaaga ttaaagcaac tcttgcagga gtagctgcct tgtttgcagt
    20341 atttgctcca tcatttgtat ctgctcaaga atcatcaact tacactgtta aagaaggtga
    20401 tacactttca gaaatcgctg aaactcacaa cacaacagtt gaaaaattgg cagaaaacaa
    20461 ccacattgat aacattcatt tgatttatgt tgatcaagag ttggttatcg atggccctgt
    20521 agcgcctgtt gcaacaccag cgccagctac ttatgcggca ccagccgctc aagatgaaac
    20581 tgtttcagct ccagtagcag aaactccagt agtaagtgaa acagttgttt caactgtaag
    20641 cggatctgaa gcagaagcca aagaatggat cgctcaaaaa gaatcaggtg gtagctatac
    20701 agctacaaat ggacgttata tcggacgtta ccaattaaca gattcatacc tgaacggtga
    20761 ctactcagct gaaaaccaag aacgtgtagc agatgcctac gttgcaggac gttacggttc
    20821 atggactgct gctaaaaact tctggcttaa caatggctgg tattaagaac taacgaacaa
    20881 ataatatgta aagagtcgag gaaatccctc ggctttttta tctttccttc gcttggtaat
    20941 agatctctac ttcttttttg agatgagaca gcatagaagt ttcctcggtt agctccagaa
    21001 gggagaaccc tttttggata agtttagaat cgtctgtaca aatcccaata gggacatagc
    21061 agatagccag cctatcgtag cttttcttat tcttggcgtc ctccagtaaa gtgtagcaga
    21121 tttgcttaca catgttttta tcttgattgt atagatagag tgtggaaagg ttgagcagga
    21181 ttgctattcg caagtcatat aaatgttgat agtttttata gacttctaag cgttgcaaga
    21241 ttttctcgga ttattgacaa ataaacggac attctgatag acgattgccc tagcggctta
    21301 ttgtaaactt tgcaaatttg gcttgtaatt ttttttataa aattcacttc gattacttga
    21361 cagttattat attttcactt attatataga taaaaggatg ggatgggagt ttaaaaattt
    21421 gaaagcgcta tccataataa taacgcataa ttttctcctt ttcgtgaaaa aagttaacgt
    21481 aattttaaaa tgagcttaat aagaggtact atgtaggtag aaaataaaga taggagaaaa
    21541 agtatgaata aaaaaatatt ttgtattcta gtatgtatta tatcattgat tagtctagct
    21601 ataatctttc catggggctg gtcgatataa tgtaagggag cttgagttgt tagtggagga
    21661 taaaatgtta agagtaatag tagttattca atctttagta ataatactgc ttgctgttgc
    21721 tttattatta tctcggaaaa actttgattc gttaaatgtt gttcttataa tgatgatcgt
    21781 atcacaattg ttgttattag tatatttgat aaaatcaggg aatcagtgat tagctgttat
    21841 ttgaattaag taaactgtta agcttcaagc agtaactggt tttaaatatt taaaataaga
    21901 taaaggaagg aagtctaatt taggtaacta aacaaagcct gcgatcactt gttaggaaac
    21961 catcctaacc atgcttaata aaaaaggaga aaataaatgg aactcgtatt accaaataat
    22021 tatgttgctc ttgagcaaga agagatgatg tatcttgatg ggggtggtgt tggtcgtaac
    22081 tggtggaata gtagaggtag ttttgcaaca gttctggatg tagatttggc catctatagt
    22141 ggtggtgcaa caatttattc tgctgatgcg ataaaaaaag ctatctcagc taatagaggg
    22201 gctattacga gaacattacg tagtttaata attaaacatg taggtagtgc agctggccat
    22261 ttagtcaata ctgcactaaa cgttgcacta actgttactg gattttcact aggtggagca
    22321 atcgcatatg gggttgattg ggctgacggt agcttagatg gttatatttt tgcttaaaat
    22381 gaaacatttt tttgcaggaa ttggtgaaat aaactttgta agttatttat tgtatatatg
    22441 tgtaggaata gccccttttt ttcacgtata tataataggt tctgaaatga attttgtgaa
    22501 aatagtgtta tctattttgg gaattatatt tgtttgtatt ttaactattg ctcgaattta
    22561 taggactttt ttctataaag aatagtttgg acttgaaatg tatttaaaaa caagaggttg
    22621 gtagattatc agcctctttc ttgtcgttga aaaagtgaga tatattgact tttgaaaaaa
    22681 atgtcataat tgagttggga taaacgtaaa agtcatactt tctcgttaaa tcgttcggcg
    22741 attctatgaa aaggtcgagg agctccctcg acttttttta taatttcttt ggttgataat
    22801 gggtctctac ttcttttttg agatgagaca gcatagaagt ttcctcggtc agctctagga
    22861 gtgagaaacc tttttggata agtttagcat tatctgtaca aatcccaata cggacatagc
    22921 agatagcaag cctatcgtag cttttcttat tcttggcgtc ctccagtaaa gtgtagcaga
    22981 tttgcttaca catgttttta tcttgattgt atagatagag tgtggaaagg ttgagcagga
    23041 ttgctattcg caagtcatat aaatgttgat agtttttata gacttctagg cgttgcaata
    23101 tttttccagt gatgagatgg aggtattcaa tgggaaaact gaaaagaatg gtattgagga
    23161 tttttagatc actctcatac catgtatctt gtttttcaat tcttctccaa agttttttga
    23221 caacctgttc tgcgtgatct gatagttccc ctgccccgtg ttgacggata taaatgacaa
    23281 cttcaagcat atctctgatt tcttctatag ggagatcgtg gtgggtcttg aggtagtctt
    23341 ggcatttttg aaataaattg acaagatcgc tggtcccgat aatggaacgc atattgagat
    23401 aggtttgcat aatctctgtg cgttgacttg gttgataaag ttgacagata tattcaaact
    23461 cttcaaaact catattgatt tgacggagaa gaaattccat attttcatat tttggggttg
    23521 tcttgccact ttcgattttt gataagctgg ttcttgagag aacaccccca cagacctctt
    23581 cttgggtcag cccctttgac tcacgtattt ctttatagac ctttccgaaa tcataacgca
    23641 tgattttctc ctttctgtga aaaaagttaa caaataataa aatcttgtta aaaatattgt
    23701 atcatagcag tgtaaaaagt aaaaaagaaa gtaaaaataa atttgtgaaa aaagttaacg
    23761 taattttaaa atgagcttaa taagaggtat gatgtaggta gaaaataaag ataggagaaa
    23821 aagtatgaat aaaaaaatat tttgtattct agtatgtatg atatcattga ttagtctggc
    23881 cataatcttt ccatggggct ggtcgatata atgtaaggga gcttgagttg ttaaaggagg
    23941 cttagtcctt ggacaaaaat ctgctgtact acaatgcttg gaaagatatc aagaacaaag
    24001 aatgatacga ttgaaactaa actgattcaa gaactactgg gcagtgattg aggtttgggt
    24061 gacatcaaag aaaagttaga ttaattctaa agaattgagt atttctatgt taaaaaaata
    24121 tccttgtacg atgcaacatg atcagtcaga ttgtgctgcg gcagttgttt caacagttct
    24181 tttatcttac aaaaaggaac tatcaatcat gaagattcgg gaaattattg gtacagacat
    24241 gtatggaacg actgtcagtg gtattgtttc aggtctgaat aagttgaatt ttacagtaaa
    24301 agctgttcga gtagcactgg aagatttgac tccaaaatta acatttcctg cgattcttca
    24361 agttaagaat gatttaggtc aaaatcattt tgtggtatta catagtataa aggagaaaat
    24421 aaagggaact cgtattacca aataattatg ttgctcttga gcaagaggag atgatgtatc
    24481 ttgatggggg ggcttattta agcaagagtg cttgtcaagg aatttgcgca gctttagcta
    24541 tgagtccagg aacttttata gcattgactg gagctgcagt tttaacaaaa aaactaataa
    24601 actatattaa ggttggaggc cttggaggtt ggcttattgg tgcagcagca ggtgtattgg
    24661 ctcttatctt tttgataaaa atttgtgtag atactacgat aaaggttcta ttaaacagaa
    24721 tctttaaggc aagtaaggta atgaaaagga ggatattttc tctttttgta ctagatttga
    24781 tggtctatat atttttaggt tatgttttag tgatacaaaa agacgtatat ctgttttcaa
    24841 ttctgataat tttttctaat ttttcagttc cctttatcag agaaaaagag tatgaattat
    24901 ttaaaaataa gaaatgagat agatatggta gctttattaa aactgagaat aaagtttggg
    24961 agatattttt atttatttta ggtgtgttgt taattgtaat ttcattacta agtcccccaa
    25021 aaattaaatt ttggaaatag agttagtgag aaggatagga taatagtatt atgatgattg
    25081 ttttaatttc agttattgtt gcattcctgt atcataaaat tacagagtat gtcaacaaca
    25141 ggaaaattga tattgttatt tttctatcat tgctgatttc tcattttatt tggaattact
    25201 attttttacc aattgaaata ttgatagcaa ttagtggagc aaatttatta ttaagttttt
    25261 taaaaaaatt acagactaaa taatattaat ctgtgtaata cagtagctcg gtcattagat
    25321 tctattgaag atataaatta aaaacgaggt tgggaaaaaa ctcaatttga aaatgagatt
    25381 gagtaaatct ttctatctat ataacgtata tcatcaatat ttttgaacac ctgataatat
    25441 gcatttttct tattttaaag attttttgcc tttcttcatt tcttgaatga atcggagaga
    25501 tgactttatt taggtgtttg acattactat agataggatt tagcagtact aatatgaact
    25561 catattatag gtgcagactt aaattttgga agcaagctaa aggatatctt atctaggtaa
    25621 ctaagtgcta taaacaaagt caacgatcac ttgttaggaa actatcctaa ctatgcttaa
    25681 taaaaaagga gaaaataaat ggaactcgta ttaccaaata attatgttgt tcttgagcaa
    25741 gaagagatga tgtatcttga tgggggtggt gttggttgta actggtggaa caaacgtgat
    25801 aatattgctg cagctgcagt ttctggaggg atgtcagtat accagacata tgccattaaa
    25861 aagttaattg ctaatcgtgg tatgatgagc cgagtcgtta gaagtgctat aacaagatat
    25921 attggtggag ttagtatggc aactattact aatgctctta atattgcggc tactgttgct
    25981 gaagtcttct cattaggagg agccattgca tatggtttag atatcgtaga cggtaaattt
    26041 gatggatatt tatgggcgta aaactatagc tatgaaacat ttttttgcag gaattggtga
    26101 aattcatttt ttgttatttt tattatatct aagcatgtct accagtccaa ttattggact
    26161 agtgattgga tatactaaaa taaatctaat aaattctatt attatagctc ttggtatgat
    26221 attggcatta attttggtat tatcaagagt gtatagaaaa tatttttata gagacgatga
    26281 tgactaaagt ttttatcaat aatttgggct ccttgtcaac tgtagtgggt tgaataaaag
    26341 ctaacgtctg gggaagggtt taaagctttg ctttatcaaa tattgactta cagagttgct
    26401 ctattgtatt gatgtattct tagtaaataa tatggtgttt tgaatgaaag atgatcagaa
    26461 atatttatta gcgggatttt attcgcttct agttgcaata ttttattttc cattgattga
    26521 ttccaagggg atttttgtaa gtatattgat ggcggtttta cttttatatt taatatactt
    26581 cattggaaca gtcattcata ttgtgataat taagtttata agaaaaaaat cttttaagta
    26641 tttggttcta tatccattta cttatgatgg gagctggaga tttcaaccta taaacttact
    26701 ctactttcca gaaatggtga gagatgtcat tccgattaat ttagttcaag aatattgcca
    26761 aggacaacct tacggactgt taaaaaagat gctgaaaaga attcgattgt cacgagagat
    26821 atctttactc ctggctacca ttatcgtcta tttttttacg catagaattc tacctctttc
    26881 agtatttacg ttcatgtttt cttacatatt gctatttgca caatcttatt tgggtggtaa
    26941 taccgtttgg attggaaata gaagattaat aatagatgat gaatttgaaa aaatcttgct
    27001 ttcaaaaagt tatgtaaaag aaatatcatc tgcacgatac tcggaatact tgacatgtga
    27061 atacaaaaac cttacaccaa tcatattgtt agctattttt gaaaatttgc ttgactccta
    27121 cttgcttcag aatcagagta aggttgactt agatattttt tataaagttt tacctttgct
    27181 ttataaagaa aaatatacta tgggattcaa ttactttgta agtttaaatt atttactata
    27241 taaggttgga tttttgggaa tcatttacga taatgaagca ttaagagatt tgtcaaaaca
    27301 atatttaaac aaaaatattt cggaattaca agatggttct ttcgagggcg gtatacaaga
    27361 tgctgttgcc tctaaacaaa tagtagttat aaatgaattt atagcttgtt taaattccag
    27421 atgcgtgcca tcccaatatg atagattttt ttataaagat agaccttata ttttttccag
    27481 aaagagtcct attaaggggt gaaaatttgt tacatttgga ttaacaagtg tcctagggat
    27541 tagaaataac tctagtatag ctagatattt ttgagtaact agaaatatca ttaggctacc
    27601 catatgattg ccagaaaaga tggctgatga atcttattta tactgttgca gtaggcattg
    27661 tctaggataa ataagctatc ttgatggggg agattggaat aattttagta gaaacattaa
    27721 aggattatgg acaagtagcg caggattagg tgatgcaatg tgctaagttg gcttggtgtt
    27781 agcagtagta ttatttaaca atggaaagta gactaaatga aaaataaacg ttattttttt
    27841 gacacaattt taataatttt actgcttata agcacgatat tttgtgtcag cccagtattt
    27901 ataaaattgg acatcttagg aactccctct catgccatct taacctttgt attggcgata
    27961 ccgttattct atattttgtc tcaatgctta catactttgc tattactagt ttcctcaatc
    28021 ttttgtaaat taagaccaat ttatttttat tttatatttg tgatcattat aggagctagg
    28081 aaatactatc gaattctctt tcaccaacta atgggattta gtccaggaat agcagtgttt
    28141 tataaggaga gtcaaacaac taagaatctg tttaaatttt actacttctt gtactttaca
    28201 acactaattt catactattt tttctttact tttgtgtatg acaaaccgtt gcttttgcct
    28261 cttattccat tttctattat catagcatta gtacaaaaac tttatagaat tgagaatcaa
    28321 caattatttc tgttaaaatc aaaggtacta acaatactgg aatctaagag ggattgtgag
    28381 tttaatcttc aggattatca tgaaatttgg aaattgcaat caaaatctga gttgccatgc
    28441 gtggctttat cttatatcag tttgatcaag ccatatcttt cagagagcgt gcgtgaacaa
    28501 attgatttat tagaagttaa gcgatttaaa aaaataaatc atccaatatc actttatggt
    28561 atgttggatg ttataaaatt aaatctatat ttacggcatt ataatgaaaa aaataaatat
    28621 gaatcaatgt taaataaaat tttagaggta agaccagact ttgttttaat cgagcagaat
    28681 attgatgata gtttaaatag ctcgcaacca ttatctttat ctttagccat ttcagaaatc
    28741 caacttttgc ttgaagtgta tatggggatc aaacatgttt caattaggag ataaaaccag
    28801 aataatattt gccattatag gggcaagttg catattagtc agtatgtatc ttattccact
    28861 tattaaaact gagaataaat tttgggaaat acttttattt atattaggtg tattgctaat
    28921 tggaattgcg ttattaagtc aaaaaaaata aattttgaaa tagtattagt gagttcgcaa
    28981 tcatttattg ctagtggttt agaactgtta agtttcaaac aataattgat tttaaacctt
    29041 aggtaaccta taaaaacaaa taaggtagag aaaggatatc ttatctaggt agctaagtga
    29101 taaaaacaca gtcgtctatc acttgttagg aaactatcct aactatgctt aataaaaaag
    29161 gagaaaataa atggaactcg tattaccaaa taattatgtt gttcttgagc aagaagagat
    29221 gatgtatctt gatgggggat tttctattcc gagatggcct gttgcaacag ccattaatat
    29281 agcttttaat ggtgttttag gtggaggagc aatcagtcta gttagaaatt atattcgtaa
    29341 ttatggtttg cggcgagtta caagcgcaat tgctggagca gctgcaagat atgttggggt
    29401 acgagttgca aatagagtgg caggatttgc actgtctgct attaatggat ttgcagcttg
    29461 gatgtcaatt ggcgatgcta ttacaacaat ctgggccaat aatgatgtaa ataggagaga
    29521 cccaaattta aacgccttgt ggtaactaga tatgggtatt aaaatggaaa aaatttttgt
    29581 tattattttt tttgtatgtc tatttatatc atccataact tttttagcct atgattttgt
    29641 tagcgaagaa ataaaaaagt tgattatttg gattaatgtc gtttttttga ttttaatcat
    29701 agcaatgatg atttatccaa aattaagaaa atgataagga cactgtaaaa ttatgatacg
    29761 taaactaatt gttttcttac taatgctccc tctttttgtc ttgtggctag agttgcatgt
    29821 cctagtgaat aacttactat tgaatctaga atctcccctt gattttgtga ttagtatgag
    29881 tcttgctttc tgtagtttga ttttatcaaa aatagtttta gacatactat acgcattgaa
    29941 agatttatac aagaaagaag gtcttattaa gatttttccc tttattttta taagaaggaa
    30001 aaaagtgaat gtgagattct cgccctattt ttcattccat cgtaaaagtt tgtcgcctga
    30061 tgatttaaga tctaggatta tatggagttt tattcttgaa attgctatta tcctagtatt
    30121 tattttaaaa attccttttg caatcatcat gcttactaca atatttttct ggactataat
    30181 ggatatcaat catctcgttt ttaataagac ggaatttctt tttaatcaaa acaaatggca
    30241 aaaagaagat tcatttgaaa gtaatttgca taagatattg atggacaaaa tacaaaaatc
    30301 agaattaagc tattctgact taatgtccct tcttctctat gatgcgatga accaatccac
    30361 ctttttaacg gatagtgaac tttttgagga tattttgaaa aaaatcgaag attctcataa
    30421 cacccttctg tgtacaggtc ttgtcgagtt actgctgtat gagatttcta ttagtaacaa
    30481 taacaactgg caagaaaagg ttgataaaat tagaatacag ctcatcagaa taaatcaatt
    30541 agattttttc tattatacaa gttggttaag gcaaaatttt gatttctgta tgaatagaga
    30601 gtatcataaa atgaaatctc ggaaattatt actgagtaat aaaaagatag tttaagttcg
    30661 tcctatttgt aaaacaaatg aaacaatttc aactaaggag gagaaaacaa atggaacttg
    30721 tattaccaaa taattatgtt gtgattgatg aagaagtaat gatgtatctt gatgggggag
    30781 cttatttaag caagcgtgct tgtcaaggaa tttgcgcagc tttagctatg agttcaggaa
    30841 cttttatagc attagctgga gctgcagttt taaccaaaaa actaataaac tatattaagg
    30901 ttggaggtct tggaggctgg cttattggtg cagcagcagg tgtattggct acagcagcag
    30961 ggaaaatagc ttactgtatt ggatatggtg ttcttaatag aggttgtgat attaacggga
    31021 acccttatcc ttgggatgga ttcatatctg caacagtaag atgagtaatg tagataagat
    31081 tcgaaaaata cacatcatcg tgtgttgggt gtatatattt ttatcattca gggcgattat
    31141 aaatgatacg gagtattttt tgcttatttt tttagctttt atctactcaa tagtatcact
    31201 acctctatat tctgtgaaaa ataaaatagt atctatctgt ctagccataa attcgattct
    31261 gttaatgagt tttcccattt taatcaataa gtttttccca gaaagttttt tgacttatac
    31321 cgtattaata agtgttttta ttacagagtt gataattttt catttaattg ggaaagattt
    31381 tgatactaaa ttgactaacg aatataagaa aattagtcag ttcagaagca aggtgtctca
    31441 atctccttgg ataaaatatt tagagatttc tagttttata ttaactatat ttccatccat
    31501 tctttatggt acagttgata atcatgtact gactcttatc tttttgataa aaatttgtgt
    31561 agatactacg ataaaatttt tattcatcag attatttgac acaagtactt taatgaagag
    31621 gagaatattt tttcttttcg cattggatgt tatagcttac ttatttttag gatatctttt
    31681 agtgattcaa aaagcaggct atttgttttc ggttttactt cttttttcta atttttcagt
    31741 tccatttatc aaagaaaagg aattcgaatt atttaaaaat agcaagtaat agaaacatag
    31801 gttaaatctt agaacggctt aaaatcagat atgataaagg gaaatagtct tatctaggta
    31861 actaagtgct acaaacacag tcgaggatca cttgttagga ttacatttta atcatgctta
    31921 ataagaatgg agaattccta tggggattgt attactctga agtttcgaat accttagttc
    31981 tcgtgatttt gagctattct aggtttagaa tccttcagaa tgtaaaattt taagcagtca
    32041 aagacttaga atagcccgaa aacatttatt ttatagcaat tctaggctta gaattgctca
    32101 tatatatgta tttgagctgc tcgatagtta ggacagcttt attctgagaa atctgagcta
    32161 tcaatgcttc agaatagtat ttcgccaatg gtttttattg aagaggtgat tgttttatga
    32221 tagtctaaaa taaaactgat ttaatggagt aaatggagaa tcgttacatg aaacattttt
    32281 ttgcaggaat tggtgagata aaacttgttg gctacttatt gtatatatgt gtaggactag
    32341 cccctctttt tcatatatat gtcataggtt cggaactgag ttttgtgaaa atagtgttat
    32401 ctattttggg agttatattt gtaagtatgt taactattgc tcgaatttat aggacttttt
    32461 tctataaaga atagtttgga cttgaactgt atctaaaaac agaggttggt cgattatcag
    32521 cctctttctt gtcgttgaaa agagtgagat atattgactt ttgaaaaaaa gatgtcataa
    32581 ttgagttggg ataaacctaa aagtaatata gtagattgaa tctggaatag tccgttatga
    32641 ctgttaaaat atttctagaa attaatttga ctttcctaat cgatttgttc acatcttgtt
    32701 tcaatctact atactttctc gttaaaccgt tcggcaattc atggtgacat ggacacatgg
    32761 tagtaagcac actatgtggc ttggcagagc taaaaactgt tcccttgcaa taagcctaat
    32821 aagcacaaca tagggagtta gagaagccga ctctaatcaa ccactttggg caatagtgag
    32881 aactgccctg tgctttttta ttttgaaaaa atatggagtt tgtcgttgaa attacttgat
    32941 tgtattttgg actatcaaga aagattcaat ggaaaaacat gtcaagtatc aacgaattat
    33001 aagtatttag agattttcaa agtgaatttt tgcttgactg atttacatca tttatttggc
    33061 ttacacaaaa tcacacgaga ttatgctagt caaacaaaac ctgctattca aactggtgtt
    33121 tttattttag aagattttag aaatatccta ttgtacaatg atgtaatcga aaggatatct
    33181 ttatatgagt ttataagtga tattttctat tctaaaataa caagttgttg catcgtagct
    33241 aaggatttat ctaaaaatac tatgaaattg gacgtcatat tttttgagga taaaaataaa
    33301 agatccgcag ttttaggttt acgaagagat aaaagcggag tatttaaacc agttactcta
    33361 cattttacaa gcgctaagaa atatgctaaa gttcgtaaaa cagatgtgaa agaaatgaaa
    33421 tggctataaa gattgtccgc aggcttaagc ttgcgttttt tgttgtttaa cgaaattaaa
    33481 aaataagctc tctcatcgga aatgttttta taggaatgaa ggaagatgat gctatgttta
    33541 aaaagagaat cgaaaagggc aaaagtagtg tctttatctt tttggagtag aagcttatga
    33601 tatagaaatt gtaataaaaa tgtaatataa aacatttgac aaatatttac ggagggagta
    33661 tacttaatat aagtatagtc taaaaatgac tatcagaaaa gaggtaaatt tagatgaata
    33721 agaaaaaaat gattttaaca agtctagcca gcgtcgctat cttaggggct ggttttgtta
    33781 cgtcttcgcc tacttttgta agagcagaag aagctcccgt agctagtcag tctaaagctg
    33841 agaaagacta tgatgcagcg aagaaagatg ctaagaatgc gaaaaaagca gtagaagatg
    33901 ctcaaaaggc tttagatgac gcaaaagctg ctcagaaaaa atatgacgag gatcagaaga
    33961 aaactgaaaa gaaagctgct gcggtaaaga aaattgatga agaacatcag gcggctaatc
    34021 ttaaatctca gcaagcatta gttgaattct tagctgctca aagagaaggt aatcctaaaa
    34081 agaaaaaagc tgcgcaagcc aagttagaag aagcagaaaa agcagaaaag gagaagaaaa
    34141 aggaatttga taaagcacag gcagtggtag ttcctgaagc aactgagtta gctgagacta
    34201 agaaaaaagc agacgaagct aaagtaaaag aaccagaact tactaaaaaa ctagaagaag
    34261 ctaaagcaaa atcagaagaa gctgagaaaa aagctactga agccaaacaa aaagtggatg
    34321 cagaacatgc taaagaagtc gttcctcaag ctaaaatcgc tgagttggaa aatgaagttc
    34381 agaaactaga aaaagatctc aaagagattg atgaatctga ctcagaagat tatgttaaag
    34441 aaggtctccg tgctcctctt caatctgaat tggatgccaa acaagctaaa ctatcaaaac
    34501 ttgaagagtt gagtgataag attgatgagt tagacgctga aattgcaaaa cttgaaaaaa
    34561 atgtagaaga tttcaaaaac tcaaacggtg agcaagctga acaataccgt gctgcagctg
    34621 aagaagactt agctgctaaa caagctgaat tagaaaaaac tgaagctgac cttaagaaag
    34681 cagttaatga gccagaaaaa ccagctccag ctccagaaac tccagcccca gaagcaccag
    34741 ctgaacaacc aaaaccagcg ccggctcctc aaccagctcc tgcaccaaaa ccagagaagc
    34801 cagctgaaca accaaaagca gaaaaaacag atgatcaaca agctgaagaa gactatgctc
    34861 gtagatcaga agaagaatat aaccgcttga ctcaacagca accgccaaaa gcagaaaaac
    34921 cagctcccgc accaaaacca gagcaaccag ctcctgcacc aaaaataggc tggaaacaag
    34981 aaaacggtat gtggtacttc tacaatactg atggttcaat ggcaacagga tggctccaaa
    35041 acaatggttc atggtactac ctcaacgcta atggttcaat ggtgacagga tggctccaaa
    35101 acaatggttc atggtactac ctcaacgcta atggttcaat ggcgacagga tggctccaaa
    35161 acaacggttc atggtattac ctcaacgcta atggtgctat ggcgacagga tggctccaaa
    35221 acaacgattc atggtattac ctaaacgcta gcggcgctat ggcaacaggt tgggctaaag
    35281 tcaacggttc atggtactac ctcaacgcta atggtgctat ggctacaggt tggctccaat
    35341 acaacggttc atggtactac ctcaacgcta acggtgctat ggcaacaggt tgggttaaag
    35401 tcaacggttc atggtactac ctcaacgcta acggttcaat ggcaacaggt tgggtgaaag
    35461 atggagatac ctggtactat cttgaagcat caggtgctat gaaagcaagc caatggttca
    35521 aagtatcaga taaatggtac tatgtcaatg gtttaggtgc ccttgcagtc aacacaactg
    35581 tagatggcta taaagtcaat gccaatggtg aatgggttta agccgattaa attaaatcat
    35641 gttaagaaca tttgacattt taattttgaa acaaagataa ggttcgattg aataaattta
    35701 tgttcgtatt ctttaggtac ctatcttatg atttcaggaa atgtcattaa aaaaacgact
    35761 ccttttctct aacttgaaaa atagattaga gaaaatgggt tgttttattt attatagtta
    35821 tttgaatgaa gataagaaga aggtatactc acgtcattca catgatctgt atattgacta
    35881 taagttttaa aaaacaattt ttaagctctt ccttgtcttc tctaaccaag cgtgttataa
    35941 tgaatactgc tcaagcgacc ttcaatcgtg aagcacacac gaccttcaat cgtgaataaa
    36001 cgaatagatg ggagacttac catgagtgat aactctaaaa cacgtgttgt cgtggggatg
    36061 agtggtggtg ttgattcgtc ggtgacggct cttttgctca aggagcaggg ctacgatgtg
    36121 atcggtatct tcatgaagaa ctgggatgac acagatgaaa acggcgtctg tacggcgacc
    36181 gaagattaca aggatgtggt tgcggtggca gaccagattg gcattcccta ctactctgtc
    36241 aattttgaaa aagagtactg ggaccgcgtt tttgagtatt tcctagcgga ataccgtgcg
    36301 ggacgcacgc caaatccgga cgttatgtgc aacaaggaaa tcaagttcaa ggcctttttg
    36361 gactatgcta tgaccttggg ggcagactat gtagcgactg ggcattatgc tcgagtggtg
    36421 cgtgatgagg atggtaccgt tcacatgctt cgtggcgtgg acaatggcaa ggatcagacc
    36481 tatttcctca gccaactttc gcaagaacaa cttcaaaaaa cgatgttccc actaggacat
    36541 ttggaaaagc ctgaagttcg aaaactagca gaagaagcag gtctttcgac tgctaagaag
    36601 aaagactcga cagggatttg ctttatcgga gaaaagaact ttaaaaactt tctcagcaac
    36661 tacctgccag ctcagcctgg tcgtatgatg actgtggatg gtcgcgatat gggcgagcat
    36721 gcaggtctta tgtactatac aatcggtcag cgtggcggac tcggtatcgg tgggcaacac
    36781 ggtggtgaca atgccccttg gttcgttgtc ggaaaagatc taagcaagaa tattctctat
    36841 gtaggacaag gattctacca tgactcgctc atgtcaacta gcctagaagc cagtcaagtc
    36901 cactttactc gtgaaatgcc agaagagttt acgctagaat gtacggctaa attccgttac
    36961 cgtcagcctg actctaaggt gaccgtccat gtcaaaggag acaaggcaga agttatcttt
    37021 gcagaaccac aacgcgcgat tacaccagga caggcagttg tcttttacga tggcgaagag
    37081 tgtctaggtg gcggtttgat tgacaatgct taccgcgatg gacaagtttg tcagtacatt
    37141 tagattgaca aattttctca atttgctaca ataataacag caatagaaat gatggtcaaa
    37201 gctcatggat gttgcaggct tttttgtcct gcacttcttt gtagttttga ctgtttttgt
    37261 gtcgtttaag ggaaaggaca agaatgactc aacaagactt tcggacaaaa gtagacaata
    37321 cggtttttgg tgttcgggct acagccttga ttgtccaaaa tcacaagctt ctagttacca
    37381 aagacaaggg caagtattac actattggag gtgcgattca agtcaatgaa agcacggaat
    37441 acgcggtagt ccgtgaagtg aaggaagaac tgggtgtcaa agctcaagct gggcagctag
    37501 cttttgtggt tgaaaatcgt tttgaacaag acggcgtttc ctatcacaat atcgagtttc
    37561 attatctggt ggatttgctt gaagatgccc cgttgaccat gcaggaagat gagaaaaggc
    37621 agccctgtga gtggattgac ttggataagc ttgaggatat ccagctagtt ccagcctttt
    37681 taaaaacggc cctaccagat tgggaaggcc aactaagaca cattcatctt gaagaatagg
    37741 agagaaacat gacttatcat tttactgaag aatacgatat tattgtaatt ggtgcgggac
    37801 acgctggggt tgaggcttcc ttagctgcta gccgtatggg ctgtaaggtc ctgcttgcga
    37861 ctattaacat tgaaatgctg gctttcatgc cttgtaatcc ctctatcggt ggttctgcta
    37921 aggggattgt cgtacgtgaa gtcgatgccc tcggtggcga gatggccaag accattgaca
    37981 agacttacat ccagatgaag atgctcaaca cagggaaggg gccagctgtc cgtgctcttc
    38041 gtgcgcaggc tgacaaggaa ctttactcta aggagatgcg caagacagtt gaaaatcaag
    38101 aaaatctgac ccttcgtcaa accatgatta atgagatttt ggtggaagat ggcaaggttg
    38161 tcggtgtgcg tacagccacc catcaagaat atgctgctaa ggctgttatt gtgacgacag
    38221 ggactgctct ccgtggggaa attatcatcg gagacctcaa gtactcatca ggtcctaacc
    38281 acagcttggc ttctattaac ctagctgaca atctcaagga actgggcctc gaaatcggtc
    38341 gtttcaagac aggaacccct ccacgtgtca aggcttcttc tatcaattac gatgtgacag
    38401 aaatccaacc aggagatgaa gcgcctaatc acttctcata cacttcacgt gatgaggatt
    38461 atgtcaagga ccaagtgcca tgctggttga cctacaccaa tggtaccagt catgagatta
    38521 tccaaaacaa cctccaccgt gcgcctatgt ttacaggtgt ggtcaaggga gtggggcctc
    38581 gttactgtcc gtcgattgaa gacaagattg tgcgctttgc ggacaaggaa cgccaccaac
    38641 tcttccttga gccagaagga cgtaatacag aggaagtcta tgtgcaaggc ctctcaacca
    38701 gtctacctga ggatgtccag cgtgacttgg ttcattccat taaaggtttg gaaaatgcag
    38761 agatgatgcg aacaggttat gccattgagt acgacatggt cttgcctcat cagttgcgtg
    38821 cgactttgga aaccaagaaa atctcaggtc tcttcactgc tggtcagaca aatggaacat
    38881 caggttatga agaagctgct ggccaaggga ttatcgcggg tatcaatgcg gctttgaaaa
    38941 tccaaggcaa gcctgaattg attctaaaac gaagtgacgg ttatatcggg gtgatgatcg
    39001 acgacttggt gaccaaggga accattgaac cttaccgtct cttgaccagt cgtgctgaat
    39061 atcgtctcat tcttcgccat gacaatgctg atatgcgctt gactgagatg ggacgcgaga
    39121 ttggccttgt ggacgatgaa cgctgggctc gttttgaaat caagaaaaat caatttgata
    39181 atgagatgaa gcgcctagac agtatcaaac tcaagccagt caaggaaacc aatgctaagg
    39241 ttgaggaaat gggcttcaag ccgttgacag atgcggtgac agccaaggaa ttccttcgcc
    39301 gtccagaagt ttcttaccaa gatgtggtgg ccttcatcgg accagctgca gaggaattag
    39361 atgacaagat tatcgaattg attgaaacag aaatcaagta cgaaggttac atctcaaaag
    39421 ccatggatca ggttgctaag atgaagcgca tggaagaaaa acgtattcca gccaatatcg
    39481 actgggatga cattgattct atcgcaaccg aagcccgtca gaagttcaaa ctcatcaatc
    39541 cagaaaccat cggccaagcc agccgtattt cgggagtaaa cccagcagat atttctattt
    39601 tgatggtgta tctggaaggt aaaaatcgta gtatttctaa aactcttcaa aaatcaaaat
    39661 gatatgtcgt aggcttctta cgaatgagtt caaagcttgg ctttgattca tctccaatct
    39721 cccatagttc cccgaactat gggagctaac tcaagttatg cattttccta gccttctggt
    39781 ctgattttca ttgagtttta atctaaaaag aaagcataga gaaaaacagc tccgaagacg
    39841 gggctgtttt gttgatttgt actcaatgaa aatcaaagag caaactagga agctagccgt
    39901 aggttgctca aagcactgct ttgaggttgt ggatagaact gacgaagtca gtaacatata
    39961 tacggcaagg cgaagctgac gtggtttgaa gagtattatt cttcatctgg tgtgaggatc
    40021 atcgggatga tgatcggttc acgttcggta ttttcataga ggaaggggcg aatagcgttg
    40081 acaatggcac cattgacaga ttgcacgcta gcatccttat ttttcagtgc gatacgaatg
    40141 gcattgaaga ggatacgctg gctttggcga atcaagtctc cagactctct catgtagaca
    40201 aagcctcggc tgaggatatc tgggccagac agaatcatct gcgatttgaa gtcaacagtt
    40261 gcgactgcta gaacgacacc gtcttcagat agatcgcgac gatctttgag gacagctgcg
    40321 ccaatttcac cgatacgatt tccatcgaca tagatatctt gggcgttgaa atgacctgcg
    40381 atacgagctg agtcagcagt aagggcaagc acatcgccat tgctcatgat aaagatattg
    40441 tccttctcaa caccagtatc cactgctagt ccagcgtgga ctttttgcat gcggtattca
    40501 ccgtggacag gcatgaagta ttttggctta atcaagcgga gcatgagttt ttgctcttgc
    40561 tggccaccgt gtccagatgt atggatattg ttcactttac cgtggataac ttcgacacca
    40621 gcttcagaaa tgatgttaat cagcttgttg acgctagtag tgtttccagg gatgggacta
    40681 gaagagaaga taacggtatc acctggttgt aattgtactt gacggtgggt tccgttggcg
    40741 atacgagaga gggctgccat aggctcaccc tgactacctg tacagaggat aagaacttct
    40801 cctgcaggat aatctttgat ttcatttggc tcgataaagg ttcccttagg agctttgatg
    40861 tagccaagat cgattccgtt gacaatggcc ttttccatag aacgaccaaa gaccgcaatc
    40921 ttgcgtccag tcttaatagc agcttctgtt gcctgctgga gacggaagat atttgaggca
    40981 aaggatgcaa agatgatacg tccttcaata ccttggataa tcttcataat ggactgacca
    41041 acgacttttt cagagttggt aaaggttggt acttccgcat ttgtcgagtc agacaggaga
    41101 cagagcacgc cttcttcacc aagggcagcc atacgatgca agtccgcagg ttctccaact
    41161 ggagtaaagt cgaacttaaa gtcacccgta cagacgattt tcccttgagg agtatgaatg
    41221 acaatcccca aaggctctgg aatagagtga gtcgttctaa agaaagttgc cttgagattt
    41281 ttaaaggtca actcggtgtt gtggttgatt tcgtaaagtt tggcgttgcg caagaggccg
    41341 tgttcttcga gtttcccacg gatcaaagcc aaggcaagcg gtccagcgta gatagggaca
    41401 tttgcttgct tgagtaggaa cggaatccca ccaatgtggt cctcgtgtcc gtgtgtgatt
    41461 aaaacagcct tgacgcggtc gatattgtcc acgatgtaag agtagtcagg aatgacatag
    41521 tcgataccaa gcaagtcatc ttctgggaat ttaatcccag catcgacgat gataatctcg
    41581 tcttggtatt caattccgta agtgtttttc ccgatttctc ctagaccacc gatggcaaaa
    41641 acgccgactt cttcaggttt aagagtgtag gccatattag aactccgtaa tttcgaaggc
    41701 gccagtttct ttttcgtaat cgagcaattt gtcagacaag agttcgatat actcgatatt
    41761 gtactctggg cgattttctt cgacaagttg gcgagcagtg atacggccct caagttctga
    41821 gctggcatcg atgtctaggt aaagcgtgcg tgttgtttca cggcgtgggc tacgttcttt
    41881 tgtttcttga taaaaaactt tgtaaatcat atagttcctt tctatttaca ggtcagctta
    41941 ttccaaactt ttagcagata tttgcttgat ttcattccat tttgtgtcta gattgacctt
    42001 gattcgttac aattatttca attataccac aaaatgaaaa attagtaaaa gacggaaacg
    42061 agaaagttag gggacgattt ctttggtaag cgtttgcaaa aataaagaaa atgtattatg
    42121 ttgataacgg aagtgaaatt tattgcttgt cataattcca tatagatttt aagtcaagga
    42181 ggttgcccta tgtataactt atttgctttt gctatcggag ctcgcttggt agcttttatt
    42241 gtttttgttg cttgcgttta tgcggggaat cttctatttg ccaaactgga acgatgacaa
    42301 accaagttct tgtggaaaat tacctttgtg actctctact cgctttttct cctcctcgtg
    42361 acctatgtcg tttggtttgt attttacttt ggattaaatg cttagatgcc ctgcttatgc
    42421 tggggttttt tgtttgggga tgtagagata gtagatttac gacacgaaaa ttccacccca
    42481 tctatcaaga tgaggtggtc tttgcatttt tctaacatga catgacaatg gaattttcaa
    42541 agcttattat ttttatggga gtcattgttc tgctcaaaaa tagagttgaa gcataaaaat
    42601 aaaacaatac aaacagataa atcgaatggt aaagggatag tagtaatgtt caaatcattg
    42661 agaatgctga gcaaactgta agagatgaag acaataaaat ttatccttct aaaaatgtgt
    42721 ttcttatcta gcatgactta ccaaactttt tacgaaggtc ttttccaatg gtataacctg
    42781 ccataaataa agcgatacca acacctacac caaagccacc cttgatttct tgcaattcct
    42841 tattagaaat ttcacgatag ttgttcaaat ctttcatcat agttaatctc ctcctaaaaa
    42901 ataaccagct gccaaaccag aacctataag tgctgttcca cctgcaatag ccttccaaga
    42961 tactgctact ccaaagataa ccaagggagc gagaccgcca tcaatatctg ataattcatt
    43021 ttcagataag gataaaaaat tgattgtcaa gaatgtcaaa atttgtcatt gaactttcct
    43081 ccttttttct tgttcacttt tatattcgga aaagaaaagg aaaagtgagc attttttaaa
    43141 ttatttttag ttaagtgagg gcactcttgt ctgggggcaa agaaaattcc catgtgccag
    43201 cttttgtagt ataatagtaa gcagacaaaa agataggaat gtgttatgaa agtattagct
    43261 tttgatacgt ccagcaaggc tctttctctg gctattttag aggacaagca ggttcttgct
    43321 gagacgacga ttaatatcaa gaaaaatcac agtattaccc tcatgccagc cattgatttt
    43381 ttgatggaga gtttggactg gacgcccaag gatttggacc gaatcgtggt ggcggaaggg
    43441 ccaggtagct acacaggctt gcgaatcgcg gtagccactg ccaagacctt gactcatact
    43501 ctgaacattg agttagttgg tatgtctagc ctcttggctc tggtgccata tcaacaagaa
    43561 ggcttgttcg ttcctttgat ggatgcgcgt cgcaacaatg tttatgcagg attttatgaa
    43621 aatgctaaac ctgtcatgcc agaagcgcac ctatcttttg aagaggtgct agaaaaagtc
    43681 aagggtgcta gtcaggtaac ctttgtcgga gaagttgccc cctttgtgga gcagattcaa
    43741 gaacacttgc caaggactaa ttataaagaa accttgccta atgcagccaa tcttgctctt
    43801 ttagcttggg acaaggaagc agaatccttg catgattttg tgccaaatta cctcaaacga
    43861 gtcgaggctg aggaaaactg gctcaagaac cataccgagt ctggtgagtc ctacattaaa
    43921 cgcctatgat agaaatcaag cgaattcaac aacagcctga cctagctcaa gccatctacg
    43981 ctgttatggc agctgtttac ctagtcagtc cttggactct ggagcaaatc caagcagatc
    44041 tgtcccaaga ccagacttgg tatgcattgg cttatgatgg ggcagaagtg attggatttc
    44101 tagctgtgca ggagaatctt tttgaagcag aagtcctgca aatcgctgtc aaaggagctt
    44161 atcagggtca gggaattgcg tcagccttgt ttgctcaatt gccgacagat aaggagattt
    44221 tcctcgaagt cagaaagtca aatcaacgag cgcaagcatt ttacaagaaa gaaaaaatgg
    44281 cggtcatcgc tgagcgaaag gcctactacc atgacccagt cgaggacgcc attatcatga
    44341 agagagaaat agatgaagga tagatatatt ttagcatttg agacatcctg tgatgagacc
    44401 agtgtcgccg tcttgaaaaa cgacgatgag ctcttgtcca atgtcattgc tagtcaaatt
    44461 gagagtcaca aacgttttgg tggcgtagtg cccgaagtag ccagtcgtca ccatgtcgag
    44521 gtcattacag cctgtatcga ggaggcattg gcagaagcag ggattaccga agaggacgtg
    44581 acagctgttg cggttaccta cggaccaggc ttggtcggag ccttgctagt tggtttgtca
    44641 gctgccaagg cctttgcttg ggctcacgga cttccactga ttcctgttaa tcacatggct
    44701 gggcacctca tggcagctca gagtgtggag cctttggagt ttcccttgct agccctttta
    44761 gtcagtggtg ggcacacaga gttggtctat gtttctgagg ctggcgatta caagattgtt
    44821 ggggaaacgc gagatgacgc ggttggtgag tcctatgata aggtcggtcg tgtcatgggc
    44881 ttgacctatc ctgcaggtcg tgagattgac gagctggctc atcaggggca ggatatttat
    44941 gatttccccc gtgccatgat taaggaagat aatctggagt tctccttctc aggtttgaaa
    45001 tctgccttta tcaatcttca tcacaatgcc gagcaaaagg gagaaagtct gtctacagag
    45061 gatttgtgtg cttccttcca agcagctgta ctggatattc tcatggcaaa aaccaagaag
    45121 gctttggaga aatatcctgt taaaaccctg gttgtggcag gtggtgtggc agccaataaa
    45181 ggtctcagag aacgcctagc agccgaggtt acagatgtca aggtcatcat tccacctctg
    45241 cgcctctgcg gagacaatgc aggtatgatt gcttatgcca gtgtcagcga gtggaacaaa
    45301 gaaaacttcg caggctggga cctcaatgcc aaaccaagtc ttgcctttga taccatggaa
    45361 taaagagtgg ctctttgtca agtgtagtgg gtaggcgaaa agctacaatc tggagagtac
    45421 gaaattcgta ctctcttttt tgatgttcaa agtcatcaaa atccgttttt taaaattgtt
    45481 aaagttccgg aaaccaaagg ttttgcgctt gataacctta atcaaattat tggtcgcttc
    45541 aagtttagcg ttggaataag gcagcttaag tgcgttgata atcttatctc tatcccttaa
    45601 aaaagtccaa aagaccgttt gaaaaagcgg atgaaccgtt ggcagttctt gctcaatcaa
    45661 tccaaagaaa tggtcggcat tcttctcttg aaaatgaaag agcaggagtt gatagagttc
    45721 gtagtgaacc tgtaatccct cagagtaaga aagcagctta tctcgtactt cccgatgggt
    45781 taagtgcatt gaaacgtggg ctgatagaat cgtttctgac agagcttgaa gctatcctgg
    45841 tgtagtaaat cagtccagtg gactgattta gcccgagcct agaaacgaaa aagcgagggt
    45901 tccaaaagcg cttgagcgcc cgatactcta aggattttcg gtcaaattgg ttcatgattt
    45961 ggattcgtac tcggttcata gctcggctca gatgttggac aatgtggaag cggtcaagaa
    46021 caatcttcgc ctttggaaag agttgcttag cgagccgata ataagggctg tacatgtcca
    46081 tggtgatgac ctcgaccagc tcccgaacct ctctctgata gcgttggaaa tggtttcgaa
    46141 tcaccgcata agttcgcccg tctaaaattg cgaggatgga tttggactca aaatcttggg
    46201 caatgaagct cattttgctc tttttgaagc tatactcatc ccaactcata acttttggca
    46261 acttggtcca atcggtttca aacttaaatt ccctcagttt tcggatgacg gtggaagttg
    46321 agaccgccaa tctgtgggca atctcagtca tagactgctt ttcaaggagg agctgagcga
    46381 ttttttgtct caccatgttg gaaatctggc aatttttctt gacaatggat gtttgagaaa
    46441 cgaccacctt aaggcaattc ttgcactgaa agcggcgctt tttgagatgt agtaccgtgg
    46501 gtaaaccctg acagtcgaga agcggaattt tagaggcttt ctggaaggcg tatttgatca
    46561 tcttcccttg acaatgagga caaggaggag cgggggaatc caactttgcc tgaacgacta
    46621 gatgggtttg gtatttcaga acagacaaga ttttgatatt tttgtctttc aatccgagca
    46681 aatctgtggt attcttaagt tgttccatat gaaccctttc taatgagttg gttagacgct
    46741 tttcattata ggtcatatgg ggcttttttt ctacaagaaa cgaccctata attcctgggg
    46801 tgggattacc cactacagaa attatagagc caaaacattc caaagtcttg tctgactctg
    46861 gaatgttttc tgttcacagt tgttttgtaa ctgcctaata agtaaccgcg ctataacgag
    46921 gtatctaccg agattgtcaa ttctccagta tactgttata aaaaacaaaa ctggaggatt
    46981 tttttatgtc cccccatcgt cccatcgact gttccgtagc tgcccaataa cggagcatag
    47041 tcggctgaaa caagaatagg acaaaagtgc ctcaagaaaa gcatcgtaat ttgacaatat
    47101 tattctgaga tgtttttgat gtaagcccat attttctcaa tgggattata ctcgggtgaa
    47161 taggtaggaa gtggtaacag tctatgccct gctccttaca catgttcatt ctgtgaaacc
    47221 ttgcattgtc cataatgata agggatggtg tatctaaagt aggtagtaag aatttttgga
    47281 agcaagcttc gaaaaagtca ctcgtcatcg tatctttata ggtcatcgta tctttatagg
    47341 tcatcggagc catagtatat tgaaacaaaa aagggcatta gtacttctat aacagtatcg
    47401 caatctctgg tgtgcgttgt ctcgatctta attcaaataa ttatatcttc ttccagagag
    47461 actaactgcc tgctcaaggc tcgatcatat tcgagataaa aataggtctc aacccctgtc
    47521 tcataaatat aaataggagt caggtagctt aagtgattca attctttaag gaaccgattt
    47581 actttttctg ggtcttgttc gcagtaggta cggctctttt ttagactata tcccatagcc
    47641 tttagagcgt aatgaatagt tgttggagga cagttgaatt cagcagctat ttcagtcaaa
    47701 taagcatcgg gatgagtttc aatatagatc tttaatttat ctctatcaac tttttcaatt
    47761 aatagtggaa gttttcttga agttagtgta ttgaaacgtt tttatacagt gctaaaattt
    47821 gaagtgtagt gcagatgtat ttgtaatagt attatagcaa ttctttggag aaggtcgaga
    47881 caagagaaaa taggtatctt tgagatataa gcatgattta ctataaaatt attgagttat
    47941 tcataaaaat ttctctatca aatatcataa tgcgtcgttt aaggagatgg ttacaatgca
    48001 atatagttgt ggaaaaataa atattaatat ccctgatgga tatggagaca ttaaggatat
    48061 agtgttttcg gctcatatta tagttaggta taataatgga cattgtggag gcatagatcc
    48121 gcatataatt ggactttgta aaaagcagat cagaaggatg tctctatatc ctattttgat
    48181 aatcgtatct agagattcaa aggttattga tgattataaa aatttagata ttgcctatgt
    48241 tgattgtact caatgttcaa ataattttga aactgcctta cacgttaaaa atattttaaa
    48301 attattaaaa atccaactta tacactgtca tggctactca actaattatt ttttatatat
    48361 gttaaaaaaa cttgacaaga atggatttgg aaaggttaag acagtgataa catgccatgg
    48421 atgggttgaa tataacttaa aaaagaaatt cttgacttat tttgattttt ggacatattc
    48481 tatgggagat gcttttattt gtgtatctga aactatgaaa aaaagattgg agagtataat
    48541 aaaaaataag aagatagttg caataaataa cggaattaat gtatcaaata gcgatttaga
    48601 tgtagtaggt gttcaagact ttaaaaaaga attttgtatt ccaaataaca aaaaaatcat
    48661 ttgttatgtt ggaaggttgg atccagaaaa aaggccggat agattccttg aatttgcaga
    48721 aaaattattt ttagtcagag aagatgtgat ttttattatg gctggaaatg gtagtatgtg
    48781 ggctgctttg aaagaaaaaa tttgctattt gaaatgtaga gataatttca ggttacttgg
    48841 tgaaatctat ccagtactat agtttaccaa atatcggatt tattgtatat tccttctgat
    48901 acagaaggaa tacctatgtg tgttttagag tcaatgtcac aaggaactcc ggttttagct
    48961 agtaatgttg gcgggttaag tgaaattatt gaacataggg ttgatggatt tttatttgag
    49021 aaggaagatg ttgagggagt gtgtgcttgt gctaattttt tactcaatga ttctgagtat
    49081 ttgaaatata taggtgagaa tagtaaatca aaaataagaa aacatttttc tgtgcaaaaa
    49141 atgtttgtag aaaccatgag agtatatgat gaattattag agaagagtag tcatggatag
    49201 gaatatagat caagaattag taagtattat aataccaaca cataataggt atgaatctct
    49261 gattagagct gtgaaaagtt gtttacatca aaattataaa aatatcgaag ttat
//
LOCUS       DBERDS010000011        45503 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.011, whole genome shotgun sequence.
ACCESSION   DBERDS010000011 DBERDS010000000
VERSION     DBERDS010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.011"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            408..1694
                     /locus_tag="ACL73E_000715"
     CDS             408..1694
                     /locus_tag="ACL73E_000715"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGS0800722.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYISTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1709..2020
                     /locus_tag="ACL73E_000716"
     CDS             1709..2020
                     /locus_tag="ACL73E_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGS0800723.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2266..2994
                     /locus_tag="ACL73E_000717"
                     /pseudo
     CDS             2266..2994
                     /locus_tag="ACL73E_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            3329..4220
                     /locus_tag="ACL73E_000718"
                     /pseudo
     CDS             3329..4220
                     /locus_tag="ACL73E_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            4236..4964
                     /locus_tag="ACL73E_000719"
     CDS             4236..4964
                     /locus_tag="ACL73E_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800724.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            5350..5559
                     /locus_tag="ACL73E_000720"
     CDS             5350..5559
                     /locus_tag="ACL73E_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0800725.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            5549..6037
                     /locus_tag="ACL73E_000721"
     CDS             5549..6037
                     /locus_tag="ACL73E_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGS0800726.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            6153..7613
                     /locus_tag="ACL73E_000722"
     CDS             6153..7613
                     /locus_tag="ACL73E_000722"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGS0800727.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGAQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            7610..8434
                     /gene="nadE"
                     /locus_tag="ACL73E_000723"
     CDS             7610..8434
                     /gene="nadE"
                     /locus_tag="ACL73E_000723"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGS0800728.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            8784..9335
                     /locus_tag="ACL73E_000724"
     CDS             8784..9335
                     /locus_tag="ACL73E_000724"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0800729.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWA
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            10380..10607
                     /locus_tag="ACL73E_000725"
     CDS             10380..10607
                     /locus_tag="ACL73E_000725"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGS0800730.1"
                     /translation="MKVPAESKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVT
                     TITYNVDGKSGQVTESTLSQKKDSQTRVVKK"
     gene            10796..11185
                     /locus_tag="ACL73E_000726"
     CDS             10796..11185
                     /locus_tag="ACL73E_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS0800731.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(11846..12874)
                     /gene="queA"
                     /locus_tag="ACL73E_000727"
     CDS             complement(11846..12874)
                     /gene="queA"
                     /locus_tag="ACL73E_000727"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGS0800732.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            13025..13732
                     /locus_tag="ACL73E_000728"
     CDS             13025..13732
                     /locus_tag="ACL73E_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGS0800733.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            13872..14048
                     /gene="rpsU"
                     /locus_tag="ACL73E_000729"
     CDS             13872..14048
                     /gene="rpsU"
                     /locus_tag="ACL73E_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGS0800734.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            14178..15113
                     /gene="hprK"
                     /locus_tag="ACL73E_000730"
     CDS             14178..15113
                     /gene="hprK"
                     /locus_tag="ACL73E_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGS0800735.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            15106..15894
                     /gene="lgt"
                     /locus_tag="ACL73E_000731"
     CDS             15106..15894
                     /gene="lgt"
                     /locus_tag="ACL73E_000731"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGS0800736.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            15895..16321
                     /locus_tag="ACL73E_000732"
                     /pseudo
     CDS             15895..16321
                     /locus_tag="ACL73E_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            16294..16683
                     /locus_tag="ACL73E_000733"
     CDS             16294..16683
                     /locus_tag="ACL73E_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGS0800737.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            16767..17897
                     /gene="hemW"
                     /locus_tag="ACL73E_000734"
     CDS             16767..17897
                     /gene="hemW"
                     /locus_tag="ACL73E_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGS0800738.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLNAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            17902..18639
                     /locus_tag="ACL73E_000735"
     CDS             17902..18639
                     /locus_tag="ACL73E_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGS0800739.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            18650..19423
                     /locus_tag="ACL73E_000736"
     CDS             18650..19423
                     /locus_tag="ACL73E_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGS0800740.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            19413..20030
                     /locus_tag="ACL73E_000737"
     CDS             19413..20030
                     /locus_tag="ACL73E_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGS0800741.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            20240..20641
                     /locus_tag="ACL73E_000738"
     CDS             20240..20641
                     /locus_tag="ACL73E_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGS0800742.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            20641..20919
                     /locus_tag="ACL73E_000739"
     CDS             20641..20919
                     /locus_tag="ACL73E_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGS0800743.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            20909..21682
                     /locus_tag="ACL73E_000740"
     CDS             20909..21682
                     /locus_tag="ACL73E_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGS0800744.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            21683..22987
                     /locus_tag="ACL73E_000741"
     CDS             21683..22987
                     /locus_tag="ACL73E_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGS0800745.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            23561..24439
                     /gene="pstS"
                     /locus_tag="ACL73E_000742"
     CDS             23561..24439
                     /gene="pstS"
                     /locus_tag="ACL73E_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGS0800746.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            24439..25356
                     /gene="pstC"
                     /locus_tag="ACL73E_000743"
     CDS             24439..25356
                     /gene="pstC"
                     /locus_tag="ACL73E_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS0800747.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            25346..26230
                     /gene="pstA"
                     /locus_tag="ACL73E_000744"
     CDS             25346..26230
                     /gene="pstA"
                     /locus_tag="ACL73E_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS0800748.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            26241..27044
                     /gene="pstB"
                     /locus_tag="ACL73E_000745"
     CDS             26241..27044
                     /gene="pstB"
                     /locus_tag="ACL73E_000745"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0800749.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            27057..27815
                     /gene="pstB"
                     /locus_tag="ACL73E_000746"
     CDS             27057..27815
                     /gene="pstB"
                     /locus_tag="ACL73E_000746"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0800750.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            27827..28480
                     /gene="phoU"
                     /locus_tag="ACL73E_000747"
     CDS             27827..28480
                     /gene="phoU"
                     /locus_tag="ACL73E_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS0800751.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            28637..29452
                     /locus_tag="ACL73E_000748"
     CDS             28637..29452
                     /locus_tag="ACL73E_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0800752.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(29472..30743)
                     /locus_tag="ACL73E_000749"
     CDS             complement(29472..30743)
                     /locus_tag="ACL73E_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGS0800753.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            30885..31616
                     /gene="budA"
                     /locus_tag="ACL73E_000750"
     CDS             30885..31616
                     /gene="budA"
                     /locus_tag="ACL73E_000750"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGS0800754.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            31626..32379
                     /locus_tag="ACL73E_000751"
                     /pseudo
     CDS             31626..32379
                     /locus_tag="ACL73E_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            32491..33441
                     /gene="murB"
                     /locus_tag="ACL73E_000752"
     CDS             32491..33441
                     /gene="murB"
                     /locus_tag="ACL73E_000752"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGS0800755.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            33500..34657
                     /locus_tag="ACL73E_000753"
     CDS             33500..34657
                     /locus_tag="ACL73E_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800756.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            34638..35444
                     /locus_tag="ACL73E_000754"
     CDS             34638..35444
                     /locus_tag="ACL73E_000754"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800757.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            35441..36214
                     /locus_tag="ACL73E_000755"
     CDS             35441..36214
                     /locus_tag="ACL73E_000755"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800758.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            36211..37281
                     /locus_tag="ACL73E_000756"
     CDS             36211..37281
                     /locus_tag="ACL73E_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0800759.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            37542..37781
                     /locus_tag="ACL73E_000757"
     CDS             37542..37781
                     /locus_tag="ACL73E_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800760.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            38056..38541
                     /locus_tag="ACL73E_000758"
     CDS             38056..38541
                     /locus_tag="ACL73E_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGS0800761.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            38563..41181
                     /gene="alaS"
                     /locus_tag="ACL73E_000759"
     CDS             38563..41181
                     /gene="alaS"
                     /locus_tag="ACL73E_000759"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGS0800762.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GNIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQLSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGR
                     NQAKIQELLDAVAGKL"
     gene            complement(41271..42725)
                     /locus_tag="ACL73E_000760"
     CDS             complement(41271..42725)
                     /locus_tag="ACL73E_000760"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGS0800763.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFIDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            42904..43653
                     /locus_tag="ACL73E_000761"
     CDS             42904..43653
                     /locus_tag="ACL73E_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800764.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCNRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVADASQGH"
     gene            43634..45268
                     /locus_tag="ACL73E_000762"
     CDS             43634..45268
                     /locus_tag="ACL73E_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800765.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLFMFINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTRVFRKYRSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEDKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
BASE COUNT        13214 a         8415 c        10199 g        13675 t
ORIGIN      
        1 tttttccaaa tatgttattc aacttattag ctacgtctct attcatattt gggtataaaa
       61 caaaaaatca attctaacag ttttatatca gaataataaa taaaaaagcg atattctaga
      121 ctgtatcaat ccttttccat tataggagca acagagtggg agtagtcatc taaggactaa
      181 tttatgtatt tttacgagtc agtatctttg gatactggtt tttacttttc tagacttttt
      241 gactacttgt taaaactggg ataattttcg actgtttaac agttattatg caaagtctaa
      301 aagattagaa ttgtcaaaac aatccgtcta ggcttgattt tatcctttat ttactataaa
      361 atgagaagga aaaatgtcaa acttttatat tgcaaatagg agaaattatg acaaaaacat
      421 taaaacgtcc tgaggtttta tcacctgcag ggactttaga gaagctaaag gtagctgttc
      481 agtatggagc agatgctgtc tttatcggtg gtcaggccta tggtcttcgt agccgtgccg
      541 gaaactttac tttcgaacag atggaagaag gcgtgcagtt tgcggccaag tatggtgcca
      601 aggtctatgt agcggctaat atggttatgc acgaaggaaa tgaagctggt gctggtgagt
      661 ggttccgtaa actgcgtgat atcgggattg cagcagttat cgtatctgac ccagccttga
      721 ttatgattgc agctactgaa gcaccaggcc ttgaaatcca cctttctacc caagccagtg
      781 ccactaacta tgaaaccctt gagttctgga aagagctagg cttgactcgt gtcgttttag
      841 cgcgtgaggt ttcaatggaa gaattagctg aaatccgcaa acgtacagat gttgaaattg
      901 aagcctttgt ccatggagct atgtgtattt catactctgg acgttgtact ctttcaaacc
      961 acatgagtat gcgtgatgcc aaccgtggtg gatgttctca gtcatgccgt tggaaatacg
     1021 acctttacga tatgccattt gggaaagaac gtaagagttt gcagggtgag attccagaag
     1081 aattttcaat gtcagccgtt gacatgtcta tgattgacca cattccagat atgattgaaa
     1141 atggtgtgga cagtctaaaa atcgaaggac gtatgaagtc tattcactac atatcaacag
     1201 taaccaactg ctacaaggcg gctgtggatg cctatcttga aagtcctgaa aagtttgaag
     1261 ctatcaaaca agacttggtg gacgagatgt ggaaggttgc ccaacgtgaa ttggcaacag
     1321 gtttctacta cggtatacca tctgaaaatg agcagttgtt tggtgctcgc cgtaaaattc
     1381 ctgagtacaa gtttgtcgct gaagtggttt cttatgatga tgcggtacaa acagcaacta
     1441 ttcgtcaacg aaacgtcatt aacgaagggg accaagttga gttttatggt ccaggtttcc
     1501 gtcattttga aacctatatt gaagatttgc atgatgccaa aggcaataaa atcgaccgcg
     1561 ctccaaatcc aatggaacta ttgactatta aagtcccaca acccgttcaa tcaggagaca
     1621 tggttcgtgc attaaaagaa ggactcatca atttttataa ggaagatgga accagcgtca
     1681 cagttcgagc ttaagaaagg aaaaggaaat gatagaggca cagggtttct tagtggataa
     1741 gcaaacaaga tgcattcatt accatagcaa gctggatatt attgctttac aatgctatga
     1801 ttgtaaaaag tattatgctt gttatcggtg tcatgattca ttagaaaatc acccttttga
     1861 gccgtatccc ttatctttga tacaggataa gcctatttta tgtggtgttt gtctaaaact
     1921 actaacatat aagcaatata aagaaagttt aagttgcccc ttttgttttt ctcgctttaa
     1981 tccaggttgc caaaatcata aggaacgcta ttttaaatag caaatcatct agttttgaag
     2041 taggagaaaa ctcaattcca agagaaaatg aagtaaatct tcccacaata aaacgcataa
     2101 tatcaagatt gttcaatacc tgatactatg cgtttttaag attttaaaga cttttttcct
     2161 ttatctggta ttttgactac ttgttaaaac tgggttaatt ttcaactgtt taacagttat
     2221 tatgcaaagt ctaaaagatt agaattgtca aaacaatccg tctagagtat gcgtgatgcc
     2281 aaccgtggtg gatgttctca gtcatgccgt tggaagtacg acctttacga tatgccattt
     2341 gggaaagaac gtaagagttt gcagggtgag attccagaag aattttcaat gtcagccgtt
     2401 gacatgtcta tgattgacca cattccagat atgattgaaa atggtgtgga cagtctaaaa
     2461 atcgaaggac gtatggagtc tattcactat gtattaacag taaccaactg ctacaaggcg
     2521 gctgtggatg cctatcttga aagtcctgaa aagtttgaag ctatcaaaca agacttggtg
     2581 gacgagatgt ggaaggttgc ccaacgtgaa ctggctacag gattttacta tggtacacca
     2641 tctgaaaatg agcagttgtt tggtgctcgt cgtaaaattc ctgagtacaa gtttgtcgct
     2701 gaagtggttt cttatgatga tgcggcacaa acagcaacta ttcgtcaacg aaatgtcatt
     2761 aacgaagggg accaagttga gttttatggt ccaggtttcc gtcattttga aacctatatt
     2821 gaagatttgc atgatgccaa aggcaataaa atcgaccgcg ctccaaatcc aatggaacta
     2881 ttgactatta aagtcccaca acctgttcaa gctggagaca tggttcgagc tcttaaagag
     2941 gggcttatca atctttataa ggaagatgga accagcgtca cagttcgtgc ttaatgtagt
     3001 tgtttagttt taaaaaatta tgcaaagctc catatacaac acttaaacga gattaaagaa
     3061 tggcgaaatc ccttgatgcg caagggatta gctgtctttt ttatttttta agtgataaag
     3121 tcggagctta ggtatcaaag cctatcaaat taaacaaaga agcgatgtct tagatatttt
     3181 gaaaaaaatt aataagcaga aaactctcta ttattttgtt gtagagagtt ttttgttaat
     3241 aaaattttac aaaatgacat ttatatattg cattaagtta gatatatgat ataatgttgt
     3301 taaaaagagg cgcaactttt taaactcaat aagaatcaaa gagcaaaccg agaatattaa
     3361 tggaggaata aaaaatgtaa gttataaatg taagtaagca ttatggtcat tcaatcattc
     3421 tcaaagatat aaattttgca cttaacaagg gtgaaattgt tggtctagta gggagaaacg
     3481 gagttggtaa gagtacattg atgaaaattc ttgttcagaa taatcaaccg acttcaggga
     3541 atattataag tagtgataat gttgggtatt taattgaaga accaaaatta tttttatcta
     3601 aaacaggttt agagaattta aaatatctgg caaacttata tggtgttgac tacaatcaag
     3661 aaagatttag aagtttgatc caagagttag atttgactca gtctattaat aaaaaagtaa
     3721 agacctattc tttgggtaca aaacaaaaat tagctttgct tctaactctc gttacgaaac
     3781 ctgatatatt gattttagat gaaccgacta atggtttaga tattgaatca tcacaaatag
     3841 ttttagcggt tctaaaaaaa ttagctttaa atgaaaacgt gggaatttta atatcgagtc
     3901 ataaattaga agacattgaa gaaatttgtg agagagttct tttcttggag aacgggcttt
     3961 tgacatttca aaaagtagga aaagatagtc ataatttctt gtttgagata gctttttcat
     4021 cagctacaga tagagacatt ttcattacca aacaagaatt tggggatatt gttcaggaag
     4081 agggattgag aattactatg tctgggaata ttcaaagtag tgagcttttt aaatttttta
     4141 acgaaaactc tattaaagta gttgattttg aaactaaaaa agagacgctt aaagatattt
     4201 acctaaatcg ttcaaaataa aggaaggtta taatcatgaa attaaataaa ttgaattttc
     4261 ttaaggaaaa tataagaaat ttatattcat caggcgtaat atatctcggt ttgcttatct
     4321 cgtttatacc gccgatattg cttacattct ttattctaaa gactcaaggg acatcgcttg
     4381 gtattaagca tatttcaaac ttttatgcta tgctcggtat gttaatggct gttatacatg
     4441 ctaatcgagt cattagtaga gatttttccc acaatacggt aagtttgttt tataatcaac
     4501 agaagaatcg gatgatttac gtcttgtcta attttctata tgccatctca gtttccatta
     4561 tttatgcttt gaatggcatt gtgttactag tcatagtaag taaattgggt attccaggtg
     4621 atttaggatt agattttata gtagctattg tagtcaatac aattttgtta gtcctgtttt
     4681 attttctatt atcttacatt ttctatttat acaaattgaa aagtggcttg gtatttggta
     4741 ttttagtagc tttactactc tttatcccta atatattaaa tacgatgatg atgaatacta
     4801 gtaatgattt gtttatcaaa gcaattgaac ttcttccttt ttattcttta cctgtatttg
     4861 tggcttcaaa tacgatgtct attagtcagt atcttgtggt aatcactaca atcattttat
     4921 tgtacttttt cactctcaag aaaagcaaga agtattcatt ttagtttcat ttagtattat
     4981 tttgcatacc taaaatacaa taaaaaaatc agtcatcttg gtatgctcct gctttcacta
     5041 ttcaacacgt ttttgactta tactaggctc atttccaaaa gcattatata atagtgatat
     5101 gaaaccaact aaactaaaca agaaatataa gcaataaaaa ctcgtttaaa agattctact
     5161 aaagctaata ctaaataaaa ataaaagagt aaactaggaa gtttatttca aacaacctaa
     5221 aatactgatt ttcggctgaa gataatactg gagtgcaaat taatggggtt ataataaata
     5281 gctgatagct tgtgttggtt ttggattttt taagagtaga tgagtattaa aactataagg
     5341 aggacgaagg tggctaaaaa tttaaaatta aaattagctc gggtagagcg tgatttaaca
     5401 caaggtcaac tggcagaggc tgtcggggtg acacgccaga ctattggttt gatagaggcg
     5461 ggaaaataca atcccagtct ctcgctctgc cagtctattt gcagatgttt agggaaaacc
     5521 ctagaccaac tattttggga ggaagaagat gaaaaataga ttttattatt atcaattact
     5581 agacgaaaga gaagaacaac tgttcaataa agcgggatct gaaagtttct atatctgcat
     5641 tgctttgtcg ctcctatctt atatcatttc agtattagca ccaagccttt ttaattctaa
     5701 tatgctgcta atcgttatca tcatagggac attttacttt ttcaatcgcg cccgttatct
     5761 gggagtgacc tactatagtc gttttcattt tacgattttg ggttgttttt tcctaacctt
     5821 ggctattacg gctcttttga tgttgcagaa ttatcaattc aacatagaaa tttatcagca
     5881 caatcctttg aattttaaat acctgtctgc ttgggtcatt acttatgtca tttaccttcc
     5941 gtgggtcttt attggcaatc ttggtcttaa gagctatggc gaatgggctc agaaaaaatt
     6001 tgaacaagat atggatgaat tggagagtgg agaatagctt gttactcttt tctcaatcca
     6061 gctaaaatgt gatataatag tactaattta ttggaataca tgaaagttct tgaaaatttt
     6121 catgtgtttc tagctaagga agtaggaaaa gtatgtatcc agatgatagt ttgacattgc
     6181 acacggactt gtaccagatc aacatgatgc aggtttactt tgaccaaggg attcacaata
     6241 agaaggcggt ctttgaggtg tatttccgcc aacagccttt taagaacggc tatgcggttt
     6301 ttgcaggttt ggaaagaatt gtgaactatc ttgaagactt gcgtttttca gatagtgata
     6361 tagcctattt ggagtcgctt ggttatcatg gggcgttctt ggattacctt cgcaatttca
     6421 agttggagtt gaccgttcgt tctgcccaag aaggggattt ggtttttgct aatgaaccga
     6481 ttgtgcaggt ggaaggacct ctagcccaat gtcagttggt cgaaacggct cttttgaaca
     6541 tcgtcaacta ccagaccttg gtggcgacga aggcagctcg tattcgttcg gttatcgaag
     6601 atgaaccctt gatggagttt gggacacgtc gggctcaaga aatggatgcg gccatctggg
     6661 gaacacgcgc agcggtgatt ggtggggcca atggaaccag caacgtgcgt gcgggtaagc
     6721 tctttgacat tcctgttttg ggaacccatg cccatgcctt ggtacaggtt tatggcaatg
     6781 actatgaagc tttcaaggct tacgctgcga cccacaaaaa ttgtgtcttt cttgtggaca
     6841 cctatgacac ccttcgcatc ggtgtaccag ctgccattca ggtggcgcgt gagctgggtg
     6901 ctcagattaa ctttatgggt gtgcggattg actctgggga tattgcctac atttctaaga
     6961 aagtccgtca gcaactggac gaggctggat ttacagaggc taagatttat gcttctaatg
     7021 atttggacga aaatactatc ctcaatctca agatgcaaaa ggccaagatt gatgtctggg
     7081 gcgtgggtac caagctgatt acagcttatg accagccagc tcttggtgca gtttacaaga
     7141 ttgttgcaat cgaagatgaa actggtcaga tgcgcaatac gattaagctg tctaataatg
     7201 ctgaaaaagt ttctacgcca ggtaagaagc aggtgtggcg cattaccagt cgtgaaaaag
     7261 gcaagtcaga aggtgactac atcacttatg atggtgtgga tattagcgac atgacagaaa
     7321 tcaagatgtt ccatccgacc tatacataca tcaagaagac ggttcgtaat tttgatgccg
     7381 ttcctctctt ggtggatatc ttcaaagaag gaatattagt ttacaacttg cctagtttga
     7441 ctgacattca ggattatgcc cgtaaggaat ttgacaagtt gtgggatgag tataagcgtg
     7501 tgctcaatcc gcagcactat ccagtggatt tggcgcgtga cgtatggcaa gataagatgg
     7561 acttgattga taagatgcgc aaggaagccc ttggtgaagg agaagaagaa tgagtttgca
     7621 agaaacgatt atccaagagc tgggtgtcaa accagtgatt gatgcccagg aagaaatccg
     7681 tcgttctatt gatttcttaa aaagatatct gaaaaaacat cccttcctaa aaacctttgt
     7741 actagggatt tctgggggac aagactcaac cttggcagga cgtttggcgc aattagctat
     7801 ggaagaactg cgagctgaaa cgggagacga tagctacaaa tttatcgctg tccgcctgcc
     7861 atacggagtg caagctgatg aagcagatgc tcaaaaagcc ctagccttca tccagccaga
     7921 tgtcagcttg gttgtgaata tcaaggaatc agctgatgcc atgacagctg cagttgaagc
     7981 gacaggtagt cctgtttcag acttcaacaa ggggaatatc aaggcacgtt gccgtatgat
     8041 tgctcagtat gcccttgctg gttcccatag cggagcggtc attggaacag accacgccgc
     8101 agaaaatatc acaggtttct ttaccaagtt tggtgacggc ggtgcggata ttctccctct
     8161 ttaccgcctc aataaacgcc aaggaaaaca gctcttgcag aaacttggcg cagagccagc
     8221 cctttatgaa aaaatcccaa cggcagacct agaagaagat aaaccaggcc tagctgacga
     8281 agtcgcactt ggagtcacct acgcagagat tgacgactac ctagaaggca aaacaatcag
     8341 cccagaagct caagcgacca ttgaaaactg gtggcacaaa ggccaacaca aacgccactt
     8401 acccatcacc gtatttgatg acttttggga gtaaaaaggt ccgggggacc tttttagctt
     8461 cttgccctga aattaaaaag caagaaaaac ctccactgga ggttttcagc ctctcatctt
     8521 gaaataagaa agtgagagaa ggtccggggg atcttgaacc tcgagtttag aaataagaaa
     8581 atgaggcaga ttcggtaact cgaagagttc gatttcatcg tcttacccct gcaacgatga
     8641 ctaggtttga aaaagcttgc tagatcgcat ttcaaaccag gcagcgactg cgtcaagaaa
     8701 ttagaagaca aactcgtttt ctagctgtta ctgagttgag cctttttact acgagcatag
     8761 aaataaggaa gtgaggtagc atcatgaaat ctattggtac gcaaatatta cagacagaac
     8821 gtttgatttt aagaagattt gtggagagtg atgcagaagc catgtttcaa aattgggctt
     8881 catccgctga gaatctgacc tatgttacct gggctcccca tcctgatgtc gaaatcactc
     8941 gaaactcgat tcgcaattgg gttgcttcct atactaatct caactattac aaatgggcca
     9001 tttgtctaaa agaaaaccca gagcaagtga taggagatat cagcatcgtt aagatagacg
     9061 aggctgattt aagctgtgaa atcggctatg tgctaggcaa ggcttactgg ggacatggta
     9121 tgatgacaga ggccttgaaa gctgtcttgg acttttgttt tactcaagca ggttttcaaa
     9181 aggtcagagc acgttatgcc agtctcaacc cagcttcagg tcgtgtcatg gaaaaggctg
     9241 gaatgtccta tctacaaacc attgttaatg gtgtagagag aaaaggctat cttgcggatc
     9301 ttatttatta tggtataagt agggaagaat gttgaattct attttctgtt tctatcgaag
     9361 tcaactattt attgtaaata taataattag cattccaagt ttatttgcaa ttttaaaata
     9421 gcatattgat tagtacaaga cagatgttct agttccttct ttaatctggt ttagtattag
     9481 ttaaaaaatc gctttaagct tgtaactaag agggagctaa tcgactagat tctccagccg
     9541 aacaggtggt aatgtacttt ttatagtgta atcctagctg ttgttaaatt taaaatagaa
     9601 tcctctatcg agttagggaa ttaaattcaa ccaattttat ttatgttttt tctatcaaat
     9661 tatctaatat taaaatagtc tcattctgat gagaaaacta ttctatttat actgcatcgt
     9721 tgtgtaagga atgatgaaag atgagtgaaa attatcaagt tggaatgttt gtatctaaat
     9781 atattagcat gtatttagat cagatgtctg caatccttta tatatgagat tgattacgat
     9841 atagttaaag tgttagttca atagtaaata tatcattcta agtctatttt atatataaag
     9901 tatattgttt aacgtttgat agaaaagatg ctatactaga agtaggatgt aatggcaaaa
     9961 tctaatacta ataagcgcta tgcaatacgt aaactcggaa agatttttgg ttctgcggta
    10021 atcgggctaa ctttattttt aggaggaatc tgaatacaag ttttgctcat gctgctgatg
    10081 ggattcaata tgtcagagat gatactagag ataaagaaga gggaatagag tatgatgacg
    10141 ctgacaatgg ggatattatt gtaaaagtag cgactaaacc taaggtagta accaagaaaa
    10201 tttcaagtac gcgaattcgt tttgaaaaag atgaaacaaa ataccgtagt gaaaatcctg
    10261 ttacaattga cggagaggat ggctatgtaa ccacgacaag gacctacgat gttaatctag
    10321 agactggtca tgttaccgaa caggttactg ttgatagaaa agaagccacg gatacagtta
    10381 tcaaagttcc agctgaaagc aaggttgaag aagttcttgt tccatgtgct actaaatatg
    10441 aagcagacaa tgacctttct gcaggacagg agcaagagat tactctagga aagaatggga
    10501 aaacagttac aacgataact tataatgtag atggaaagag tggacaagta actgagagta
    10561 ctttaagtca aaaaaaagac tctcaaacaa gagttgttaa aaaatgaacc aagccccaag
    10621 ttcttgtcca agaaattcca atcgaaacag aatatctcga tggcccaact cttgataaaa
    10681 gtcaagaagt agaagaagta ggagaaattg gtaaattact cttactacaa tctatactgt
    10741 agatgaacgt gatggaacaa ttgaagaaac tacttctcgt caaattacta aagagatggt
    10801 aaaaagacgt ataaggagag ggacgagaga acctgaaaaa gttgttgttc ctgagcaatc
    10861 atctattcct tcgtatcctg tatctgttac atctaaccaa ggaacagatg tagcagtaga
    10921 accagctaaa gcagttgctc caacaacaga ctggaaacaa gaaaatggta tgtggtattt
    10981 ttataatact gatggttcca tggcaacagg ttgggtacaa gttaatggtt catggtacta
    11041 cctcaacagc aacggttcta tgaaagtcaa tcaatggttc caagttggtg gtaaatggta
    11101 ttatgtaaat gcatcgggtg agttagcggt caatacaagt atagatggct atagagtcaa
    11161 tgataatggt gaatgggtgc gttaacagat tcctccctgc gacaaaattg ataatagtat
    11221 gtctgaatat ataattatat ataaaaagct atagataagg tcatcttata gcgactataa
    11281 aaaagtgaac aagcctagtc ttctgtacat tagaattcag atttgttcac tttttgttta
    11341 atactcaatg aaaatcaaag agcaaactag aaaactagtc gcaggttgct caaagtactg
    11401 ctttgaggtt gtagatagaa ctgacgaagt cagtcacata tataatccaa ggtgacgttg
    11461 acgcggtttg aagagatttt tgaagagtat aagtctttga ttttgagact aaggagagtc
    11521 agggtcaaag tagtgaatga ttctgaaata actcataata gtctcttgag aggacagata
    11581 agagtaacaa atatggtgct actcatgtgt cttgcatttt gatttacaaa cagcgaagaa
    11641 aatataggaa gctgaaataa aatatagatg aatcaatttg gagagtcaac gcaatctatg
    11701 gcaatatttt cgaagctagg gggaagcatt ttaatttcaa tgtactaggc gtcttctaca
    11761 gctagctaga gtttcaattg tagatgttct ttgaaataat atcttagcga tttattggta
    11821 ttagaagaat tagagaaatt ctttctcaat aaataaacat ggcgtcacca aaactgaaga
    11881 agcggtagtg ttcttggatg gcatggtggt aggcatctaa gactaattca cggcctgcaa
    11941 aggcagaaac caacatgacc agagttgatt ttggcagatg gaagttggtt gagaaggcat
    12001 ccacgacctt ccactcatac ccaggtttga taaagatatt ggtccaacca gaatctgctt
    12061 ggatttgccc atcaaacttg gaaccaatag tttccaaggt gcggatagaa gtggttccga
    12121 cagcgatgac gcgaccacca ttttctttga cagagcgaag ggtggcagca gcttcctcag
    12181 aaagttgata gaactctgag tgcatttcgt gttcgtccag attatccaca gaaacaggtc
    12241 taaaggttcc gagtccgaca tggagagtca gatagactag atgaacaccc ttagcttgga
    12301 tttctgccag cagttctttg gtgaagtgaa gaccagcagt cggtgctgca gcagagccgc
    12361 tttccttggc gtagacggtt tgataacgtt cacggtcatc taatttttcg tggatataag
    12421 gtggcagagg catttctccc agactttcca agacttctag gaaaattcct tggtattcaa
    12481 agcggacaat gcgtcccccg tgggtcaatt cttctgtaac gacagcgctg aggcggccat
    12541 caccaaagct gatacgagta ccgaccttga ggcgtttggc aggtttagcc agaacttccc
    12601 actcgtctcc actagtgttc ttaaggagga gaagttccac atgacctcct gtctccactt
    12661 tttgaccata gaggcgggca gggagaactc gggtgtcgtt catgacaagg gcatcaccag
    12721 gttccagcat atcaataata gagtggaaat gtttatcttg catttctcct gtctcacggt
    12781 tgacgatgag gagtttggag gcatcacgtt tttcaagggg cgtttgggca atcaattcct
    12841 ctggcaagtg gaaatcaaaa tcagctgtat tcatatattt gttcattctt tctaagttct
    12901 aatcctatcc attataacac gtttcaagtt tggacgctct ttttttagaa attaaatcgt
    12961 tttcacttga caaaaattgg tctataccat ataataaata tagacagaaa tggaggatga
    13021 aaagatgaaa gttattaaag ttgaaaacca agttcaaggt ggaaaagttg cttttgagat
    13081 tttgaaggaa aaattggcta atggagctca aactctagga cttgcgacag gaagtagccc
    13141 acttgaattt tacaaggaaa ttgttgagag tgaccttgat ttttcaaatc taaccagtgt
    13201 caaccttgat gagtatgtgg gccttgatgg ggacaatcca cagtcttatc gttacttcat
    13261 gcaagaaaac ttgttcaacc aaaaaccatt taaagaaagt ttcttgcctc gtggtgttaa
    13321 ggacaatgct gaagctgaag ttgaacgcta caaccaaatt ttggctgacc atccagttga
    13381 cctccaaatc ttgggaatcg gtcgcaatgg gcatatcggc tttaatgagc ctggtactcc
    13441 atttgacagt caaacgcatc tagtagaact tgaccagtct actatcgaag ccaatgcacg
    13501 cttctttgcc aagattgaag acgtcccaac ccaagctatt tcaatgggga ttaaaaacat
    13561 tttggatgcc aagtctatta ttctttttgc ttacggtgag tcgaaagcag aagccattgc
    13621 cggaacagta tctggcccag tgactgagaa cctacctgca agtagcctcc aaaatcaccc
    13681 tgatgtaacc atcatcgcag atgctgaagc gcttagctta ctcgaaaaat aaaaaagcaa
    13741 tgttctattg aacgctttca actcttgtat aaatggaaga aaaaatcaaa attaaaccgc
    13801 atttttgctt gacaattatt ccttttacgt gtagaatgaa atagatcttg aacttgaagg
    13861 gagtgaaaaa aatgtctaaa acagtagtac gtaagaatga atctcttgac gacgcacttc
    13921 gccgtttcaa acgtgcggtt actaaagctg gtactcttca agaaacacgc aaacgtgaat
    13981 tctatgaaaa accttctgta aaacgtaaac gtaaatcaga agtagctcgt aaacgtaaaa
    14041 aattctaatt gaaatgaaag gctagagaaa tctagtcctt tttcttttaa ataaatactc
    14101 caaagcctgc aaaaatctga aacttcctcc tacaatttga tataatagag agaagaactc
    14161 atttgaagga ggaaatgatg tcggttttag taaaagaagt gattgaaaag cttagactag
    14221 acattgtcta tggtgaacca gaattgcttg aaaaggaaat caatacagcg gatattacgc
    14281 gacctggtct tgaaatgaca ggctattttg actactatac accagagcgg attcaacttt
    14341 tggggatgaa ggagtggtct tatctgatca gcatgccttc caacagccgt tatgaagttt
    14401 tgaaaaaaat gtttctacct gagacaccag cagtcattgt tgcccgtggt ttggtggttc
    14461 cagaggagat gttaaaggct gctagagaat gtaagattgc tattttaacc agccgtgcag
    14521 ctaccagtcg tttatctgga gagttatcta gctatctgga ttctcgtttg gcagaacgta
    14581 ccagtgtgca cggtgtcttg atggatattt atgggatggg cgtcttgatt cagggagata
    14641 gtggaattgg taagagcgag acaggtcttg agcttgtcaa acgtggtcac cgtttggtag
    14701 ccgatgaccg tgtcgatatc tttgccaagg atgagattac tctctggggt gaaccggctg
    14761 aaattttgaa acacttgatt gaaattcgtg gggttggtat tatcgatgtt atgagtctct
    14821 acggtgcgag tgctgtcaag gattcttcac aggttcagct tgctgtctat ttggaaaatt
    14881 acgatacgca taagaccttt gatcgtcttg gaaacaatgc agaggaactt gaagtttctg
    14941 gcgtagccat tcctcgtatt cgtattccag ttaaaacagg tcgtaatatc tctgttgtga
    15001 ttgaggcagc tgccatgaat tatcgtgcca aggaaatggg ctttgatgct acccgtttgt
    15061 tcgacgaacg actgacaagt ctcatagctc gaaatgaggt gcaaaatgct tgatccaatt
    15121 gctattcaac taggacccct agccattcgt tggtatgcct tatgtattgt gacaggcttg
    15181 attcttgcgg tttatttgac catgaaagaa gcacctagaa agaagatcat accagacgat
    15241 attttagatt ttatcttagt agcctttccc ttggctattt taggagctcg tctctactat
    15301 gttattttcc gatttgatta ctatagtcag aatttaggag agatttttgc catttggaat
    15361 ggtggtttgg ccatttacgg tggtttgata actggggctc ttgtgctcta tatctttgct
    15421 gaccgtaaac tcatcaatac ttgggatttt ctagatattg cggcgcctag cgttatgatt
    15481 gctcaaagtt tggggcgttg gggtaatttc tttaaccaag aagcttatgg tgcaacagtg
    15541 gataatctgg attatctacc tggctttatc cgtgaccaga tgtatattga ggggagctac
    15601 cgtcaaccga ctttccttta tgagtctcta tggaatctgc ttggctttgc cttgattctg
    15661 atttttagac ggaaatggaa gagtctcaga cgaggtcata tcacggcctt ttacttgatt
    15721 tggtatggtt tcggtcgtat ggtcatcgaa ggtatgcgaa cagatagtct catgttcttc
    15781 ggccttcgag tgtcccaatg gctgtcagtt gtccttatcg gtctcggtat aatgatcgtt
    15841 atttatcaaa atcgaaagaa ggccccttac tatattacag aggaggaaaa ctaaatgtta
    15901 gaagttgcat atattcttgt tgccctagct ttaattgtct ttttggtcta tctgatcatt
    15961 actgtacaaa agcttggtcg tgtcatcgat gaaacagaaa agacgattaa aaccttgact
    16021 tcagatgtgg atgtgacctt gcatcacacc aatgagttgt tggctaaggt caatgtcttg
    16081 gcagatgata tcaatgtcaa ggtggctacg attgatccac tcttcagtgc tgttgcagat
    16141 ttatctctat ctgtttcaga cctcaatgac catgcgcgtg tcttgagcaa gaaagcttca
    16201 tcagctggtt caaaaacact caagactggt gcaagtctgt cagctcttcg tcttgcaagt
    16261 aaatttttca aaaaataaaa aaggagaatc cttatgggta aattatcctc aatcctttta
    16321 ggaacggttt caggtgcagc tcttgccttg tttttaacaa gtgataaggg caaacaagtt
    16381 tgcagtcagg ctcaagattt tctagatgat ttgagagaag atccggagta tgccaaggag
    16441 caagtctgtg aaaaactgac agaagttaag gagcaggcta cagattttgt tctgaaaaca
    16501 aaagaacagg ttgagtcagg tgaaatcact gtggacagta tacttgctca agctaaatcc
    16561 tatgcttttc aagcgacaga agcatcaaaa aatcaattaa ataatctcaa ggaacaatgg
    16621 caagaaaaag ccgaagctct tgatgactca gaagagattg tgattgatat aacagaagaa
    16681 taaaccatca ccatctccgg acggactatg tatctgggga tggtgatttt tatctggaat
    16741 ctagtctttg tggtataata attactatgc agaaaaaacc aacgtcagcc tatgtgcaca
    16801 tcccattttg tacccagatt tgttattatt gtgatttttc aaaggtcttc atcaaaaatc
    16861 agccagtcga cagctattta gagcatctgc tggaagagtt tcgttcttat gatattgaaa
    16921 agttgtcaac cctttatatc ggtggtggaa caccgacagc cctgtcggct ccgcaactgg
    16981 aggttttact gaatggcttg actaaaaact tggacttgtc tgtcttagaa gagttgacca
    17041 ttgaagccaa tccaggcgat ttgaatgcgg ataagatagc tgttttgaaa aattcggctg
    17101 tcaatcgtgt ttcgctaggt gtccagacct ttgatgataa gatgttgaaa aagattgggc
    17161 gcagtcattt ggagaaggat atttatgaaa atatcgatcg cctgaaactg gctggttttg
    17221 acaacatctc cattgatttg atttatgctc tgcctggtca gaccatggag caagtaaagg
    17281 aaaatgtggc taaagccatt ggactggata ttccccacat gagtttgtat agtttgattt
    17341 tagaaaacca tacggtcttt atgaaccgga tgcgacgtgg gaaattgcct ctgcctaagg
    17401 aggaactaga agcggagatg tttgagtaca tcattgcaga gctggagcga gcgggttttg
    17461 agcattatga gatttctaat ttctccaaac ccggctttga aagtcgtcat aatctcatgt
    17521 actgggacaa tgctgaatac tatggtattg gtgcaggggc atctggttat gtcaatggag
    17581 tacgttataa aaatcatggt cccattcgtc attatctcag tgcggttgag gaaggcaatg
    17641 cttgtattac agaagatcac ctgagtcaaa aggagcaaat ggaagaagaa atgttcttgg
    17701 gactccgcaa gaaatccggg gtttccatgg cgcgatttga ggaaaaattt ggacagtctt
    17761 ttgctggact ttatggagaa attgtcagag atttggttca acaaggcctc atgcagattg
    17821 agggtgacca cgttcgcatg acaaagagag gtctcttttt gggagatact gtagcagaac
    17881 gatttatttt ggagtaggat catgggctta acttatcaaa tgaaaatgaa aattcctttt
    17941 gatatggctg atatgaacgg tcatatcaaa cttccagatg tgattttgct gtcactgcaa
    18001 gtttcaggga tgcaatcgat tgaactggga gttagtgata aggccatttt ggaagactat
    18061 aatctggtct ggattatcgc agaatatgat attgaggtgg ttcgtttgcc tcgttttgcg
    18121 gaagaaatta ccatcgaaac ggaagccttg agctacaatc gacttttttg ctaccgtcgc
    18181 tttactattt ataatgaagc ggggcaggag ctcatccata tgatggcgac ctttgttctc
    18241 atggaccgcg acagtcgaaa agtccatgct gttgaacctg agattgtggc tccttaccag
    18301 tctgattttg ataaaaaact tatccgtgga ccgaagtatg aatccttgga agagccgatc
    18361 agcaaggatt accatgttcg tttttacgac ttggatatga atggtcatgt caataacagt
    18421 aaatacttgg actggatttt tgaggtcatg ggagcggatt ttttgaccca ctatattccc
    18481 aagaaaatca acctcaagta tgtcaaggaa gttcgaccag gtggggtgat tacatcggct
    18541 gttgaacgga ctggactgga aagcaagcat gaaattacaa gtgatggggt tatcaatgcc
    18601 caagcaatca ttacttggca agaaataaaa aaggtttagg gagaaataga tgaaatataa
    18661 aggctattta attgatttag acggaaccat ttataagggg aaagaccgaa tccctgctgg
    18721 agagactttt gttcatgaat tgcaaaagcg ggacattccc tatctctttg taaccaacaa
    18781 tacaacccgc actccagaga gtgttaagga gatgttggct cagaatttta atatcgatac
    18841 gcctctatcg actgtctaca cagcgacttt ggcaaccatc gactatatga atgatttggg
    18901 gcttgaaaag actgtctatg tcgtcggaga agcaggactc aaggaagcca tcaaggcggc
    18961 tggttatgtg gaagacaagg aaaaccctgc ctacgtggta gttggtctgg attggcaagt
    19021 cgactatgaa aaatttgcca cagcaactct tgctattcaa aagggtgccc attttatcgg
    19081 aaccaatcct gacctcaaca tcccgacgga acgtggtctt ttgccaggtg ctggctcact
    19141 gattacgctg cttgaagtag cgacacgagt gaagccggtt tatatcggaa aaccaaatgc
    19201 catcattatg gacaaggcgg ttgagcactt aggtttggaa cgtgaagagt taatcatggt
    19261 tggggacaat tatttgactg atatccgggc tgggattgac aatggcattc caacgctctt
    19321 ggtgacgaca ggttttacta aggcagaaga agtagctggc ctgccaatcg caccgacaca
    19381 tgtggtttct agccttgcgg agtgggattt tgatgaaaac taaattgacc ttttggggct
    19441 ctatgctctt tctcctctcc ctctcaatcc ttctgaccat ttatctggct tggattttct
    19501 atcctatgga gattcagtgg ctaaacttaa cgaatcgagt ctatctaaaa ccagaaacca
    19561 ttcaatacaa ttttcatatc ttgatgaatt atctgaccaa tccttttagt caggtcttac
    19621 agatgcctga ttttcgttcg tcagcagctg gtctgcacca tttcgcagtg gtcaagaatc
    19681 tctttcattt ggttcagcta gtagctctag tgacactgcc aagtttctat gtctttgtca
    19741 ataggattgt gaaaaaggac tttttgtctc tttatcgaaa aagtctcctg actctagtag
    19801 tcttacctgt gatgattgga cttgggggag ttttgattgg ttttgaccaa ttctttactc
    19861 ttttccatca aattctcttt gtgggagatg atacctggct ttttgatcca gccaaggatc
    19921 ctgttattat gattttgcca gagaccttct ttcttcatgc cttcctcctc ttttttgccc
    19981 tctatgaaag cttctttggg tatctgtgtc tgaaaagtcg taggaagtga aatgaaagat
    20041 gtttttaatt tgcatatata aaaatatata tcgtttaaaa ccatcgttaa gagtgaatta
    20101 accaaatcca attgtgtcaa tcgttcgcaa acagcctatt tttcttgaaa aaataggctt
    20161 tttttctaaa aatccctagt caagcgcttt atttttttgt ataatagaag tagcaaagta
    20221 tagataagaa gagaaaagca tgattacact atttctatca ccgagctgta catcatgtcg
    20281 taaggctaag gcctggttag aaaaacataa ggttcccttt gtggaacaca atattatgac
    20341 cagtccttta acaagaaaag aattgcaaca catcctttcc ttgaccgaaa atggtactga
    20401 tgacatcatt tcaactcgtt caaaaatttt tcaaaaattg aatattgatg tagagagtat
    20461 ttcggtatcg gaattgcttc atttgattga gcagtatcct agtcttttgc gtcgtccaat
    20521 tattattgat gccaagcgta tgcaaatcgg ttttaatgaa gatgagattc gtgcttttct
    20581 ccctcgtagt tatcgtaagc aagaactaaa agaagcaaga atgagagctg gtattagtta
    20641 atgaacaaac agtatagtta cccactagat ttgtcgtgga gcactgaaga acttgcttca
    20701 gtgctttctt tttttaatga tgttgaagct gcctatgaag gcaaagtaga ggctaaaaag
    20761 ttactggact cctataaggg attcaaagcg gtcgtgccaa gcaagagcga agagaaacgt
    20821 ttgggacgag aatttgaaac ggttagtggc tattcacttt accgagcagt tcaggctgcc
    20881 aaagaaaaag gggaaggaaa gatttctctt ggaaagtaaa tttgaatttg ctaaagagct
    20941 tgttaagaaa gcaggccagt acattcttga ccatatgcag gaagacttgc gtgttgaaac
    21001 caagtcctct ccaacagatt tggtgaccag actggacaaa gaagttcagg aactcttggt
    21061 tggtgagatt ttgtcccgtt atcctgagga taagatttgt gctgaagaag gttgtctgcg
    21121 agcctcggtt caagagggca aggtttgggt cattgatccc attgatggta ccaataattt
    21181 tgtagcccag caggaagatt ttgctgttat gatggcttat tttgaaaatg gtcagggaca
    21241 gtttggtctg atttatgatg tggtcaaagg ggattgttac cacggtggtg gggaatttcc
    21301 agtttgtcta aatgataggc ccctagctcc ttttaaaact aaaccacttg gagattttct
    21361 cattgcaggg aatagtggta tgctggaaac caatgaatgg gggctggctg atttgagccg
    21421 agcggttctt ggtgttcgtg tctatggaag tgcggccatt agttttgcca agattttgtc
    21481 agggcgtttg ttgacctatc tcacttatct gcaaccatgg gattatgccg cagctagtat
    21541 tttaggggaa agtctgggct atcgggttgt gacccttttt ggtgaagctc ctgattttca
    21601 aaccagacag cctgtcatga tggtgcctct tgagatgcag gaggaaattc agtcctatat
    21661 ttacgaaagg aaaagaactt aaatgcaatt tccagaagga tttgttgaaa aatataaaga
    21721 aatactagga gatgaggcaa gagattttct tgcctctttt gaggaggaag cggtttcggc
    21781 ctttcgggtc aatcccttaa aagaagagca actttccttt tctgatgcca ttactcaaac
    21841 cccttggggc cactatggga aggtttcagg gaaatcgcct gagcatgcta caggtttagt
    21901 ttattcgcaa gaacctgctg ctcaaatggt ggctcaagta gcccaaccca gtcctggtat
    21961 gaaggtcttg gacttggctg ctgcaccggg gggcaaatca actcaactgg cagcctatct
    22021 agcaggggag gggctacttg tttccaatga aatttcaagc aaacgggcta agattttggt
    22081 tgaaaacatg gagcgttttg gagcgacaaa tgtcgtggtg accaatgaat ctgccgaccg
    22141 cttggtcaag gtctttaaag gctattttga cttaatcgtt cttgatgccc cttgctctgg
    22201 tgaaggaatg tttcgtaagc aacctgatgc tatggactat tggagcttag attatccgag
    22261 tcaatgtgct agcttgcaaa gagaaattct ggaggatgca gtgaccatgt tagctgaagg
    22321 tggtcgtctg gtttattcga cctgtacctg ggcacccgag gaaaacgaag agattgtcaa
    22381 ttggttgctg gaagagtatg attttgactt gttgccagta gagcatatca atggaatggt
    22441 agctggtatt gacctgccag aaacggctcg gatgtaccct catcagttta agggagaggg
    22501 tcagtttgtt gcccatctac agtttaaggg taacaatcca gctcctaaat ttaaggcaag
    22561 taagagtaac ctcagccgtg aacaagttgc cttgtggcag gaatttgccc aaaaccattt
    22621 gaaggtcaat ctaccgggta tcttgcagat ttttggagac cagctttatc tcttgccaga
    22681 acttttgcca gatttaggga agctcaagat tgctcgcaat ggactgcatc tgggtacttt
    22741 taagaagaaa cgctttgagc ccagtttcgc tcttggttta gccttgaaac cgagtcaggt
    22801 cgaacagtcg gttgaaattg gccaagaagc gtttgtcaag tatgcggctg gagaaaccgt
    22861 tcagctggca gaaagtctgc caaatggttg gtaccaagtt ttggttaaag gcaatggctt
    22921 gggctttgca aaggttactg gaaatgtttt gaaaaattat tttccaaaag gcctcagatt
    22981 caaatgaaaa tgctagtcaa atatcttatt ctatgttata gtgaaagtat ggattttttt
    23041 agtaggatga ttcttgatat cttgattgcc atcacatgta gttttactac tcgatgaaaa
    23101 tcaaagagca aactaggaag ctagccatag atagctcaaa acactgcttt gaagagattt
    23161 tcaaagagta caagaagttt agttattagc gttcttaccg cttgtaaact agatttctca
    23221 taaaatagaa tcttttcctt ttagttgtaa actagtctgg gagagtagag aggtttgaga
    23281 tacctttcta gcttttggat tatcatctaa gaagagtaat ttcccttgca ttaaaaaggg
    23341 gaaaaagaga cacgaaatga ctataatggg tgacaatggg ggaagggata gacaagagat
    23401 tttatccaca tatgaaaaaa ggaggttagg aaagagtaat atagcctata ttatataaat
    23461 aatcaattgc gcagaaattt ggtaagaatt catgcgtcaa ctcataaaga actacttaaa
    23521 aaattcacag tattcataat tattttcgag gagaaaaaca gtgaaaaaaa gaaaaaagct
    23581 tgctctgtct cttatcgctt tttggctgac ggcttgttta gtaggctgtg ctagctggat
    23641 tgatcgtgga gaatccataa cggctgttgg ctcaactgcc ttgcaaccct tggttgaagt
    23701 agcggcagat gaatttggca cgatccatgt tggaaaaacg gtcaatgtcc aagggggagg
    23761 ttctggtaca ggcttgtccc aggttcagtc tggggcagtt gatataggaa actcagatgt
    23821 atttgctgag gaaaaagacg gaattgatgc ttctgctctt gttgaccaca aggtcgcggt
    23881 agctggcttg gctctgattg tcaataagga ggttgatgtt gataacctaa cgacagagca
    23941 acttcgtcaa atcttcatag gtgaggtaac caattggaaa gaggttggtg gtaaggactt
    24001 acccatctct gttatcaatc gggcagccgg ctctggctct cgtgctacct ttgatactgt
    24061 cattatggaa ggtcagtctg ccatgcaaag tcaggagcag gattcaaatg gagcggtaaa
    24121 atcaatcgta tcaaaaagtc caggagctat ctcttattta tctcttacct atatagatga
    24181 ttcggtcaaa agcatgaagt tgaatggcta tgacttaagt ccagaaaata taagtagcaa
    24241 taattggccc ttgtggtctt atgagcatat gtatacattg gggcagccca atgagttggc
    24301 tgcagaattt ctcaattttg ttctctcgga tgagacccaa gaagggattg tcaaaggatt
    24361 gaagtatatt ccgattaagg aaatgaaggt tgaaaaagat gctgccggaa ctgtgacagt
    24421 gttggaaggg agacaataat gaatcaagaa gaattagcta agaaaatgtt gcttccatca
    24481 aagaattctc gtctggagaa attaggaaaa ggtttgacct ttgcctgtct ttctttgata
    24541 gtcatccttg tggccatgat tttggttttc gtagcgcaaa aaggcttgtc gaccttcttt
    24601 gtcaatggtg tgaatatctt tgactttctt ttgggaggaa cttggaatcc ttctagtaaa
    24661 gaatttggtg cccttcctat gattttgggt tcctttatcg ttaccattct ctcagccctt
    24721 atcgcaacac cctttgctat tggtgcagca gtttttatga ccgaagtatc accaaaaggg
    24781 gcgaagattt tgcaaccagc tattgaactc ctggttggga ttccttcagt agtgtacgga
    24841 tttattggct tgcaagtcgt cgttcccttt gttcgcagtg tctttggtgg gactggtttt
    24901 gggattttgt cagggatttc cgtcctcttt gtcatgattt tgccgaccgt aacctttatg
    24961 acaacggata gcttgcgtgc ggttcctcgt tattatcgtg aggctagttt cgctatggga
    25021 gccactcgct ggcagactat ctggcgtgtg atcttgaagg cggcccgttc tggtattttc
    25081 actgcagtgg tctttgggat ggcgcgtgcc tttggtgagg ctctagctat ccagatggtt
    25141 gtcggaaact cagctgttat cccaacttcc ttgaccacac cagctgcaac tttaacttct
    25201 atattaacta tgggaattgg gaacactgtc atgggaactg taaataataa tgttctctgg
    25261 tcactggcct tggtactgct cttgatgagc ttagttttta acagtgtgat taaattgatt
    25321 acgaaagaaa gaggaaagaa aaattatgcg cgctaagaaa ttagataaac ttgcaacagc
    25381 tgtcctctat acgattgcta gcatcattgt gacaatcttg gcttccttga ttctctatat
    25441 cttggttcgg ggcttgcccc atatctcttg gtctttcttg actggaaggt cttctgcttt
    25501 tcaagcaggt ggtgggattg gcattcagct ttacaattcc tttttcctat tggtcattac
    25561 cttgattatt tctgtacctc tttctatggg agctgggatt tacttggctg aatatgctaa
    25621 aaaaggtcct gttaccaact ttgtgcgaac ttgtattgaa atcttgtcct ctttaccatc
    25681 agtggtggtg ggtctctttg gttacttgat ctttgtagtc cagtttgagt atggattttc
    25741 aatcatttca ggtgctttgg ccttgacagt ctttaacttg cctcagatga cgcgtaatgt
    25801 agaagatagt ttgaaacacg ttcaccatac ccaacgtgag gctggtctgg ctcttgggat
    25861 ttctcgctgg gagacagtgg ttcatgttgt tattccagaa gcgcttccag gtattgtaac
    25921 gggtgtcgtc ttggcatctg gtcgtatctt tggcgaagct gcagctctga tctatacagc
    25981 agggcaatcg gcgccagctc ttgactggtc taactggaat atcctcagtg tgactagccc
    26041 catctctatc ttccgtcaag cagaaacctt ggctgtccat atctggaaag tcaatagtga
    26101 aggcactatt ccagatggaa ccattgtatc agcaggttct gccgctgtgc tcctgatctt
    26161 tatcctgatt tttaactttg gagctcgtaa gttcggaagc tatctacaca agaaattaac
    26221 cgctgcctaa aggagaagcc atgtcaacat ataactggga tgagaagcat atccttacct
    26281 ttcctgaaga aaaagtagcc ctttctacta aggatgtcca tgtttattat ggtaaaaatg
    26341 aatccattaa ggggattgat atgcaatttg aaagaaataa aattacagct ttgattggtc
    26401 cgtcgggatc ggggaaatct acctacttac gcagtctcaa tcgcatgaat gataccattg
    26461 atattgctaa agtaactggg cagattctct atcgtggaat tgatgtcaac cgtccagaaa
    26521 tcaacgttta tgaaatgcgt aaacacattg gaatggtttt tcaacgcccc aatccatttg
    26581 ctaagtcaat ttaccgtaat attacctttg cgcatgaacg tgctggagtt aaggataagc
    26641 aagtcctaga tgaaatcgta gaaacctccc ttcgtcaggc tgccctctgg gatcaggtta
    26701 aagacgatct ccacaagtca gccttgacct tatcaggtgg tcagcaacaa cgtctctgta
    26761 tcgctcgtgc catctctgtt aagccagata tcctcttaat ggatgagcca gcctcagcct
    26821 tggatccgat tgcgaccatg caactagaag agaccatgtt tgagctcaag aaaaacttta
    26881 ccatcatcat tgtaacgcat aatatgcagc aggctgctcg tgcaagtgac tatacaggct
    26941 tcttttactt gggtgatttg attgagtatg acaagactgc aactattttc caaaatgcca
    27001 agctacagtc caccaatgac tatgtatctg gtcactttgg ttagaaagga aaccgtatga
    27061 cagatgcgat tttacaggta tcagacctgt ccgtttatta taataaaaag aaggctttga
    27121 atagtgtttc cctatctttc caacctaagg aaattacagc cttgattggt ccatctggat
    27181 cagggaagtc aaccctcctc aagtctctca accgcatggg agatctcaat ccagaggtga
    27241 ccacaactgg atccgtggtg tacaatggtc acaacatcta cagtccgcgt acagatacgg
    27301 ttgaattacg taaggaaatc ggaatggttt tccaacaacc taatcctttc cctatgacta
    27361 tctatgagaa tgttgtctac gggcttcgta tcaatggaat taaggataag caggttctgg
    27421 atgaagccgt agaaaaagcc ttgcaaggtg cctctatctg ggatgaggtc aaggatcgtc
    27481 tatatgattc agctattgga ttgtcaggtg gtcaacagca gcgtgtctgc gtggcccgtg
    27541 tcttggcaac tagtcctaaa atcatcctct tggatgagcc aacttcggct ttggatccga
    27601 tttcagctgg taagattgag gaaaccttgt atggtctaaa agacaagtac accatgcttc
    27661 tggtaacccg ttccatgcag caagcttcac gtatctctga taagacagga tttttcctag
    27721 atggagattt gattgaattt aatgatacca agcagatgtt ccttgatccc caacacaagg
    27781 aaacggaaga ctatattaca ggaaaatttg gataaggaga tgaaagatgt tacgatctca
    27841 atttgaagaa gatttagaga aattacataa ccagttctac gctatgggac aagaagtgct
    27901 ctcacaaatc aatcgtacgg tacgtgcttt tgtcacgcat gaccgtgacc tggcaaaaga
    27961 ggtcatagaa gatgatgcag aagtaaatga atacgaagtg aaactggaaa agaaatcatt
    28021 tgaaatgatc gcactccaac aaccagtctc tcaagatttg cgtacagtct tgactgtcct
    28081 taaggctgta tcagatgtgg agcgtatggg ggatcacgct gtagccattg cccaggcaac
    28141 catccgtatg aagggggaag agcgcatccc agctgtagag gaagaaatta aaaaaatggg
    28201 acgtgaagtt aaaagcgttg ttgaagcagc acttgatctt tatcttaatg gttctgttga
    28261 cgacgcatac cgggtggcct ccatggatga gcaaattaac cactattttg aaactatccg
    28321 tgaccttgcg actgaagaga ttaagaaaaa tccagaagcc attgttacgg gtcgtgatta
    28381 tttccaagtt atttcctact tggagcgtat cggtgactat gctaaaaata tctgtgaatg
    28441 ggttgtctac tttgaaacag gtaagattgt cgaactataa aatagtttaa ttctgtataa
    28501 aaaggagctt gaaatcaact gatggctcct ttttttgaac gaaaaaatat ttttgagata
    28561 aaaatttaaa aaacacttga caagtaactt ggatatcgtt ataattatac aaaattaaca
    28621 gagaggttgt ttatttatga aatcaaaaaa atggatattt gttttatgta attttcttgc
    28681 aagtttcttc ttagtagctt gccagtcagg ttctaatggt tctcagtcag ctgttgaggc
    28741 cattaagcaa aaggggaaat tagttgtggc aaccagtcct gactatgcac cctttgaatt
    28801 tcaatcattg gttgacggaa agaatcaggt agtcggtgca gacatcgaca tggctcaggc
    28861 tatcgctgat gaacttgggg ttaagttgga aatctcaagc atgagttttg acaatgtttt
    28921 gaccagtctt caaactggta aggctgacct agcagttgca ggaattagtg ctactgacga
    28981 gagaaaagaa gtctttgatt tttcaatccc atactatgaa aacaagatta gtttcttggt
    29041 tcgtaaggct gatgtggaaa aatacaagga tttaactagc ctagaaagtg ctaatattgc
    29101 agcccaaaaa gggactgttc cagaatcaat ggtcaaggaa caattgccaa aagctcaatt
    29161 aacttcccta actaatatgg gtgaagcagt caatgaattg caggctggaa aagtagatgc
    29221 tgttcatatg gatgagcctg ttgcacttag ttatgctgct aaaaacgctg gcttagctgt
    29281 cgcaactgtc agcttgaaga tgaaggacgg cgacgccaat gccgttgctc ttagaaaaaa
    29341 tagtgatgat ttgaaagaag tggtagacaa ggtcatccaa aaacttaagg atgaaggaac
    29401 ttaccaaagc tatcttgaaa aagcagcaag tctaactgaa gttgaagaat aagaaaaagc
    29461 agagttggat gtcattccaa ttctgctttt aaatagttta aaacattttc cagattgtct
    29521 agggacacct tggcaaattg ataaggacag gtgcttaaat aggcctcttc aaagaagtcc
    29581 aagcccagtt gactgtgttt gagactggcg attttaggat actgtctcag gtctagcaat
    29641 aaaccatcgt gtaggggata atgaggaagg ggacaaggtg ttttagttat cctttcctcg
    29701 atttgttttt ggtaagattc atgattggtc aagcgagcca aacgattttt ttcaaacaat
    29761 tgactgtcaa tatagagtga cagggccttt tgcataatga ggttgctgtc gtagtctagg
    29821 atatttttgt aggccacaaa tgcttctttg atagcatttg gaagaatgag tgctgtaata
    29881 cgaagggcag gaaaaaggct ggtcgagaag gacttgatat aaatgacacg ctcctctgta
    29941 tcaagatagt ggaaggtttg gcccttcttg gagtccaaat cacccagata atcgtcctct
    30001 acgatataga catcatactt ggcagctaag ttaagaatag atcgtttgtc ctgctcagaa
    30061 taggaatgtc ccagaggata gtgaaatcgg ggaatggtgt agaaaaattt aatttttcct
    30121 gttttgaagt ggccttccag ctcctccaag tcaatcccat caatgcctcg ttcaatcgtt
    30181 tgatagtcca gcccctgtgc aatcaagagg cgattcatcc gatggtaggt tggctgttcc
    30241 accaagattt ccttggcttg tctaggaaag gatatttgag agaggataaa caaggcttgt
    30301 tgggttccag aagtcagtac tagttggtta gccttgcagt agagagcttg ctcaaagagg
    30361 agtttgtgaa tggactgtct taggtcttct aatccttctt gattgtcata gtagttgaag
    30421 aggtagtttt ctcggccaat caaggtttca ttgacacaga gtcggaaatc gtcataggca
    30481 ctggcatgtt cgtcggtaac ctcgatttct aggtcttgat gttgcccttg ttctaataca
    30541 tagtagccac tctgaggctt ggcatagagg tattgttcgt gccgtaattc cagcagggct
    30601 cgttgaatgg tgtccttgct gcagtgaaag tcaaggctca gttgacggat agaaggcagg
    30661 cgactacccg tcggaaatcg ttcagactcg ataccatttt tcagatagga aacgacctct
    30721 ttgtacttgc tttgtttctt cattccagac ctcccttgat tttgttacat tgtacccttt
    30781 tttttccttc ttggcaatgt ctagagcgtt tctctcgttc acatctaggg gcaaatgtgg
    30841 tatacttagg agtaagattt atagaataac agacaagaaa gtgaatggat aagaacgtgc
    30901 aggaaccagt gaaattattt caatacaata ctcttggagc cttgatggct ggcctttatg
    30961 gtggtactat gacagtagga gaattgctag aacatggtga ccttggtttg ggaaccttgg
    31021 attccattga tggggaattg attgtcttgg atggcaaggc ttatcaggcc aaagggtcag
    31081 gagaccagcc agaaattgtg gaagtgtcac cagatgccct tattccttac gctgcagtgg
    31141 taccgcatca ggcagaggtc attttccgcc agcgctttga gatgacagac aaggaattga
    31201 aagaacgaat tgagtcttat tatgatgggg aaaatctttt ccgttctatc aagattcggg
    31261 gggaattttc acatatgcat gtgcgtatga ttcctaagtc aacacccgat accaagtttg
    31321 ctgatgtcgc aacccatcaa ccggaatata gtcgtgacaa tgttgcgggg actattgttg
    31381 gtttctggac gcctgagatt ttccatgggg tcagtgtggc aggctaccat ctgcacttca
    31441 tatcagatga tttgaccttc ggtggacatg tcatggattt tgtcatcaag gaaggcatta
    31501 tcgaggtggg agcagttgac cagttggacc aacgtttccc agtccaagac cgtcaatact
    31561 tgtttgctaa gttcaatgtt gacgagatga aaaaagatat tgaaaaggca gaataggaga
    31621 agaaaatgac cattcatatc attattacca tgttgctgtt gctagctttt ctgataggaa
    31681 gcatttggtt tgccaaaaag aaataccaga ttaatctagc tgtcttgggc ttgggtgcag
    31741 tcgctttctt tgtctcttcg cagattttgg aaaaactggt gcatatcttg attttgcatc
    31801 ctcaaaaaag acggtagtat tgccctcttg caagatcacc cgcttgtcta tattatctat
    31861 ggcctagcta tggcagcatt ttttgaggaa acggctcgtc ttgttttctt caaatggttg
    31921 gagaaaaaga gaagtttgga aaaggcagac gccttggcct atggactggg gcatggtggc
    31981 ttggagttga tttttctagg ccttactagt ttactcaatc tttacattgt tctttcggca
    32041 gttcaaactc agaatccaca ggttatgcaa ttactgtctg aaaatatgtt aaaaaccatt
    32101 cagtcacttt cggtctggca gatttatttg cttggttttg agcgaatctt ggcgcttggt
    32161 ttccaattac ttttgacagt ttgggtttac caagctgttc gccagaagaa atggatttat
    32221 ctcctagcag cctatggctt gcatgccttc tttgatctgg caccatctct ttcccaagta
    32281 ggctggttga caaatccagt cttggttgaa gtgattctag cactggagct cgttctggtc
    32341 gcctatggaa ccaaggaaat cttttgtaaa aaatcataaa aagggggaaa cctctttttc
    32401 ttatgcaaaa tccaaacaag gtatttttat ggtcgtcaaa tgtctctaaa aatggtataa
    32461 tggaatgaat tttgtaaaag gaagagtgac atgtctgtaa gagaaaaaat gcttgaaatc
    32521 ttagaaggaa ttgatatccg ttttcaggaa cccttgcata gctatagtta tacaaaagta
    32581 ggtggagagg ctgattattt ggtctttcca cgaaatcgtt ttgagttggc tcgcgttgtg
    32641 aaatttgcca accaagaaaa tatcccttgg atggttcttg gcaatgcaag caatatcatc
    32701 gttcgtgatg gtgggattcg tggatttgtc atcttgtgtg acaagctcaa taacgtttct
    32761 gttgatggct ataccattga agcagaagct ggggctaact tgattgaaac aactcgcatt
    32821 gccctccgtc atagtttaac tggctttgag tttgcttgtg gtattccagg aagcgttggc
    32881 ggtgctgtct ttatgaatgc gggtgcctat ggtggcgaga ttgctcacat cttgcagtct
    32941 tgtaaggtct tgaccaagga tggagaaatc gaaaccctgt ctgctaaaga cttggctttt
    33001 ggttaccgcc attcagctat tcaggagtct ggtgcagttg tcttgtcagt taaatttgcc
    33061 ctagctccag gaacccatca ggttatcaag caggaaatgg accgcttgac gcacctacgt
    33121 gaactcaagc aacctttgga atacccatct tgtggctcgg tctttaagcg tccagtcggg
    33181 cattttgcag gtcagttaat ttcagaagct ggcttgaaag gctatcgtat cggtggcgta
    33241 gaagtgtcag aaaagcatgc aggatttatg atcaatgtcg cagatggaac ggccaaagac
    33301 tacgaggact tgatccaatc ggttatcgaa aaagtcaagg aacactcagg tattacgctt
    33361 gaaagagaag tccggatctt gggtgaaagc ctatcggtag cgaagatgta tgcaggtggt
    33421 tttactccct gcaagaggta gtggggacct gacagagccc cgatcggtta atctatgaaa
    33481 aagaaggaat ttatgccaat tgaaaaaacc aattatcgaa ttcaaaaacg tctctaaagt
    33541 ttttgaagac agcaacacca aggttctcaa agacatcaac tttgagttgg aagaagggaa
    33601 attctacacc cttctaggtg catctggttc ggggaaatca actatcctaa acattattgc
    33661 aggtttactg gatgcgacga caggagatat catgctagac ggtgttcgta tcaatgatat
    33721 tccaaccaac aagcgcgacg tacataccgt cttccaatcc tatgccttgt tcccacatat
    33781 gaatgtgttt gaaaatgttg cctttccact tcgcttgcgt aaaattgata agaaagaaat
    33841 cgagcagcgt gtagcggaag ttctcaagat ggttcagttg gaaggttatg aaaaacgttc
    33901 catccgcaaa ctttctggag gacaacgtca gcgtgtggcc atcgcccgtg ctatcatcaa
    33961 ccaaccccgt gtggtcttgt tggacgagcc tttatcagcg ctggacttga aattgagaac
    34021 agacatgcag tacgaattgc gtgaattaca acaacgattg ggcattacct ttgtctttgt
    34081 cactcacgat caggaagaag ctcttgccat gagtgactgg attttcgtta tgaatgatgg
    34141 cgagattgtc cagtctggaa cccctgtgga catctacgat gagccaatca accactttgt
    34201 tgccaccttt atcggggagt caaacatctt gccaggtacc atgattgagg actacttggt
    34261 cgaatttaac ggcaaacgct ttgaagcggt tgatggtggg atgaagccaa atgaacctgt
    34321 tgaggtcgtt attcgtccag aggacttgcg cattaccctt cctgaagaag gcaaactcca
    34381 agttaaggtc gacacccagc tcttccgtgg agttcattat gaaattatcg cctatgacga
    34441 acttggaaat gaatggatga tccactcaac ccgtaaggcc atcgtgggtg aggaaatcgg
    34501 tctggacttt gaatcagaag acatccacat catgcgtctc aatgaaaccg aagaagagtt
    34561 cgatgctcgt atcgaagaat acgtggaaat cgaagagcaa gaagcaggtc tgatcaatgc
    34621 gatcgaggag gaaagagatg aagaaaacaa gctctaaact ctttgtagtg ccctacatgc
    34681 tttggattgc cctctttgta ttggcaccct tggtcttgat tttcggacaa tcctttttca
    34741 acattgaagg ccagtttagt ttagaaaatt ataaatctta ctttgcgtca caaaacttga
    34801 cctacctcaa aatgagtttc aactcagtgc tttatgcagg cattgtgacc tttgtgacct
    34861 tgcttatcag ctatccaaca gccctctttt tgacccgtct caagcaccgt caactctggc
    34921 tcatgctgat tatccttcct acctggatca atttgctcct taaagcctat gcttttatcg
    34981 ggatttttgg tcaaaatggc tctattaacc aattcttgga atttatcgga attggttcac
    35041 aacagttgct ttttaccgat ttttccttta tctttgtcgc aagctacatc gagctcccct
    35101 ttatgatttt gccgattttc aatgtcttag acgatatgga taataatctc atcaatgcta
    35161 gttatgacct tggtgcaact aagtgggaga ccttccgtca tgtcatcttc cctctatcta
    35221 tgaacggtgt gcgaagtggg gttcagtcgg tctttatccc aagtttgagt ctcttcatgc
    35281 tgacccgttt gattggtggg aaccgcgtta tcaccttggg gacggctatt gagcagaatt
    35341 ttctaaccaa tgacaactat ggtatgggtt caaccatcgg tgtgattctc atcctgacca
    35401 tgttcatcac catgtgggtg actaaggaaa ggagagaacg atgaaaaaat ttgccaacct
    35461 ttatctggga ctggtctttc tggtcctcta cctgcctatc ttttacttga ttggctatgc
    35521 ctttaatgct ggtgatgata tgaatagctt tacaggtttt agctggactc actttgaaac
    35581 catgtttgga gatgggagac tcatgctgat tttggctcag acatttttct tggccttcct
    35641 atcagctttg atagcgacca ttatcgggac ttttggtgcc atttacatct accagtctcg
    35701 taagaaatac caagaagcct ttctatcact caataatatc ctcatggttg cgcctgacgt
    35761 tatgattggt gctagcttct tgattctctt tacccaactc aagttttcac ttggcttttt
    35821 gaccgttcta tctagtcacg tggccttctc cattcctatc gtggtcttga tggtcttgcc
    35881 tcgactcaag gaaatgaatg gcgacatgat tcatgcggcc tatgacttgg gagctagtca
    35941 atttcagatg ttcaaggaaa tcatgcttcc ttacctgact ccgtctatca ttactggtta
    36001 tttcatggcc ttcacctatt cgttagatga ctttgccgtg accttctttg taacaggaaa
    36061 tggcttttca accctatcag tcgagattta ctctcgtgct cgcaagggga tttccttaga
    36121 aatcaatgcc ctgtctgctc tagtctttct ctttagtatt atcctagttg taggttatta
    36181 ctttatctct cgtgagaagg aggagcaagc atgaaaaaaa tctattcatt tttagcagga
    36241 attgcagcga ttatccttgt cttgtgggga attgcgactc atttagatag taaaatcaat
    36301 agtcgagata gtcaaaaatt ggttatctat aactggggag actatatcga tcctgaactc
    36361 ttgactcagt ttacagaaga aacaggaatt caagttcagt acgagacttt tgactccaac
    36421 gaagccatgt acactaagat aaagcagggt ggaacgacct acgatattgc cattccaagt
    36481 gaatacatga ttaacaagat gaaggacgaa gacctcttgg ttccgcttga ttattcaaaa
    36541 attgaaggaa tcgaaaatat cggaccagag tttctcaacc agtcctttga cccaggtaat
    36601 aaattctcca tcccttactt ctggggaacc ttaggaattg tctacaacga aaccatggta
    36661 gatgaagcgc ctgagcattg ggatgacctt tggaagccgg agtataagaa ttctatcatg
    36721 ctctttgatg gggcgcgtga ggtgctggga ctaggactca attccctcgg ctacagtctc
    36781 aactccaagg atctgcagca gttagaagag acagtggata agctctacaa actgactcca
    36841 aatatcaagg ctatcgttgc ggacgagatg aagggctata tgattcagaa taatgttgca
    36901 atcggcgtga ccttctctgg tgaagccagc caaatgttag aaaaaaatga aaatctacgt
    36961 tatgtggtac cgacagaggc cagcaatctt tggtttgaca atatggtcat tcccaaaaca
    37021 gttaaaaacc aaaactcagc ctatgccttt atcaacttta tgttgaaacc tgaaaatgct
    37081 ctccaaaatg cggagtatgt cggctattca acaccaaacc taccagcgaa ggaattgctc
    37141 ccagaggaaa caaaggaaga taaggccttc tatcccgatg ttgaaaccat gaaacaccta
    37201 gaagtttatg agaaatttga ccataaatgg acagggaaat atagcgacct cttcctacag
    37261 tttaaaatgt atcggaagta ggagataaac gtaagaagac gaatcagtca agctggttcg
    37321 tttttaagga atagaagtca gtttttagag ccctatcttt ttctattcta gttgtttatt
    37381 tgtttatttg cttatttgct tgcctagtag tatactaagc ctatactctt caaaccacgt
    37441 cagcgttgcc ttgccgtact caagtacagc ttgaggctag cttcctagtt tgctttttga
    37501 tttttattga gtattaacct tacagaaagc ggcaacaaat aatgaaaatg tctacttttt
    37561 tcaaaaaaag tttctggcca acctttatga ttgttaacca aactgctata ctattccatt
    37621 taaaggatgg cttggatcga caatacctaa caactgagtc catatattgg gtgataggca
    37681 cctttatatt tggaaatatt ctagtagctg tgtttagtaa tatgaaaatt tgggataaaa
    37741 agaaaaacgg cagtaagaaa aaatatatcc tgaaaaagta atcagagatg tagggaattg
    37801 gtctaattca acggagatca tttccagttg acgcaagctt aaaaaaacgt tataataaga
    37861 aagttgagaa ttgattttca cttgtcttag tccagagaaa tggcggtgct gcgagccatc
    37921 taagctagga agtcatgctg ctcaatcata caattgcata agaacaagag aatgacaagt
    37981 tcattgaatg aaggtggtac cgcggttttt cgcccttcgt gatatgagct tgtcttttga
    38041 tttttggagg tgttgatgaa aacatttctt gtcaaacaaa agtttcgtct tggaggcgaa
    38101 cgcttcgcta tcaaggatga caggggagaa attgcctatc aggtggaggg atcatttttt
    38161 aagattccta aaacctttac catctatgat gcggctggtg aacaagtcag tgagattagt
    38221 aaagaaatct tgaccttgct tcctcgtttt gagattcagc ttcgggatgg ctcgagtttt
    38281 gtcattcgta agaagttgac cttctggcga gataagtatg agtttgataa tctaggtctt
    38341 cgtatcgagg gcaatatctg ggatttgaat ttcaaattgc tggatgatcg cgatcagttg
    38401 attgcggaaa ttaagaagga actcttccat ctgacctcta cctataccgt aacggttctt
    38461 gaagacgctt atgcagacct agtcatttcc ctctgtgtcg cgattgacta tgtggaaatg
    38521 ctggaaagcc aatcacatta aacaagtaaa taaggagaca atatgaaaca actatctagt
    38581 gcacaagtac gccaaatgtg gcttgatttc tgggcgacca aaggtcactc agtagaacca
    38641 tcagtaagtt tggttcctgt aaatgaccca actcttttgt ggatcaactc tggggtagca
    38701 acccttaaga aatactttga cgggaccatt atccctgaaa atccacgtat taccaatgcc
    38761 caaaaggcta tccgtaccaa cgacatcgaa aacgtaggga agactgcgcg tcaccatacc
    38821 atgtttgaaa tgttggggaa cttctctatc ggggattact tccgtgacga agctatcact
    38881 tgggcttatg agcttttgac aagccctgaa tggtttgatt tccctgctga aaaactttac
    38941 atgacctact atccagacga taaagattct tacaaccgct ggattgaagt gggagtggat
    39001 ccaagtcact tgattccaat tgaggacaac ttctgggaaa tcggtgcggg accttctgga
    39061 ccagatacag aaatcttctt tgaccgtggg gaagcctttg acccagaaaa tatcggtctt
    39121 cgcctgcttg cagaagatat tgaaaacgac cgttatattg aaatctggaa catcgttttg
    39181 tcacaattta acgcagaccc tgctgttcct cgtagcgaat acaaggaatt gccacataag
    39241 aacattgata cgggcgctgg tttggagcgt ttggtggctg ttatccaagg ggctaagacc
    39301 aactttgaaa cggacctctt tatgccgatt atccgtgaag tcgagaaatt gtctggtaag
    39361 gtttatgacc aagatggcga caacatgagc ttcaaggtta tcgcagacca cattcgttct
    39421 ctttcatttg ctatcggtga tggtgccctt ccaggaaatg aaggtcgtgg ttatgttctt
    39481 cgtcgtcttc tccgtcgtgc ttctatgcat ggtcaaaaat tgggtatcaa cgagcctttc
    39541 ctttacaaac ttgttccaac tgttggaaac atcatggaaa gctactaccc agaagtgctt
    39601 gagaaacgtg actttattga gaaaatcgtt aagagcgaag aagaatcatt tgcccgtacc
    39661 cttcactcag gtcaacactt tgcccaaggc attgtggcag acttgaaaga aaaaggtcaa
    39721 tctgtcattg ctggtcaaga tgtctttaaa ctctatgata catacggatt cccagttgaa
    39781 ttgactgaag aaattgctga agaagctggt atgactgtag accgtgaagg ttttgaagca
    39841 gccatgaaag aacagcaaga acgcgcgcgt gcgtcagctg tcaagggtgg ctcaatgggt
    39901 atgcaaaatg aaactcttca aaacatcact gtagaaagtg tcttcaacta caatgctagc
    39961 caattgtctt ctaaattggt agctatcgtt gctgacaatg cagaagtagg agctgtttca
    40021 gaaggaactg cctctcttat ctttgcggaa acgtcatttt atgctgaaat gggtggacag
    40081 gtagctgact acggacaaat cttggatgag tcaggtaagg ttgtggctac tgtgaccaat
    40141 gttcagaaag ccccaaatgg tcaagccctt catacagttg aagtccttgc accgcttgcc
    40201 ttgaaccaag aatatacctt ggcaattgat agcaatcgcc gtcaccgtgt catgaaaaac
    40261 cacactgcga ctcatttgct tcacgctgcc cttcacaata tccttggaaa ccacgcaaca
    40321 caggcaggat ctcttaacga agttgaattc cttcgctttg actttaccca cttccaagca
    40381 gtaactgctg aggaacttcg tgcgattgaa cagcaagtta acgagaaaat ttgggaagca
    40441 cttgaagtga agacagttga aacggatatt gacactgcta aagaaatggg agctatggcc
    40501 ctctttggtg agaaatacgg caaggaagtt cgtgtcgtga ctatcggtga ctactctatt
    40561 gaactttgtg gtggtactca tgttggcaac acttctgaga ttggtctctt caaaattgtc
    40621 aaagaagaag gaatcggttc aggaactcgc cgtatcttgg cagtgactgg taaggaagcc
    40681 tttgaagcct atcgtgaaca agaggatgct cttaaagctg tcgcagcaac cttgaaagca
    40741 cctcaagtca aggaagtacc tcacaaggta gaaggacttc aagaacaact tcgtcaactt
    40801 caaaaagaaa atgctgagtt gaaagaaaaa gccgcagctg cagccgcagg cgatatcttc
    40861 aaagatgcta aggaagtcaa cggtcatcgt tacattgcta gtcaattgtc tgtatccgat
    40921 gccggtgccc ttcgtacttt tgcagataac tggaaacaaa aagactactc tgatcttctt
    40981 gtcctagttg ccgctatcgg tgacaaagtc aatgtccttg tagcaagcaa gacaaaagac
    41041 cttcatgcag gaaaccttgt caaagaatta gcaccaatca tcgatggacg tggtggtggt
    41101 aaaccagaca tggccatggc aggaggaaga aaccaagcta agatccaaga attgttggat
    41161 gcagtagcag gtaaattgta atcaagtaaa gatctatcca tttgggtagg tctttttgtg
    41221 aatacaaaaa agccaaatcc gcttggacct agcttggtta ttatgagcta ttagatggta
    41281 ttgactgccc agacacttac ggatctagct gagacaggga attgtccata accttcctca
    41341 tcaattgtaa cttgaccttg gtggttacca agtaaatcta caaaggtttg attagtccat
    41401 tcttgaccga caaacattga cttgctgttt tcttggtcat ttgagataag gactgcgatt
    41461 ggggattgat tttcagcacc tgaacgtacc caaccgatac agttagcatg gtcaaagtag
    41521 tcattttgtt ctccataggc caagtctttt cggatggcta ggaggcggtc aaggatttct
    41581 ttgaaatctt cttgagcata ctggcctgaa atcccatagt agtctccgta aaagacacat
    41641 ggaaggccgt cttggcgtaa caaaatgagg gcataggctg ctggcttgaa ccattcttca
    41701 acggtagact caagggcttg tcctcgttgg gtatcgtggt tgtcgataaa agtcacagcc
    41761 ttgtcaggct tgagttcaac caggctatct gtgaaaatgc cacgaaggtc atagtttgcg
    41821 ccagcttgac tggcttcaaa gagattctgg tggagacgaa catcgacaag gtcaaagtgt
    41881 tcttccgttt tttcgagata gtccagattg gcttccttgt ctgggttcca aaattcacca
    41941 aaaacataga aatcgtcacc gtatttttcc ttcatatcgc ggatgaaatt gcgcataaag
    42001 aaagagtcaa tatgcttaac ggcatccaaa cggaaaccag ctacaccagt cgtttccatg
    42061 aaccaatcag cccagtcata gatgttttgg atgacttcag gatgtttaaa gtctaggtcg
    42121 gcatacatga ggtagtcgta gtttccgttt tcgttatcga ccaattcctc gttagcccag
    42181 cccttgttgt ctccttggat taggtaaatc ccggatttac ggcgtttggc atcatagtct
    42241 gtacctgtga agtggtacca gtgccagtgg aagtcattgt aggtatcttg gcgaccatcg
    42301 aaggtaaaac tagtccagcc attgatggtg aagggttctc caagttcaac tgtacggtct
    42361 acaggatcca cttcaataac ctgaaaggct tccctgtgat cagcagcagc cttgtggttg
    42421 agaactacat cggccatagg ttgaattccc tgcgctttaa gggcttgaat ggcttgaaga
    42481 tagtcttctt tgaaaccata cttggtgcgg acagtccctt tttggttgaa ctctcctaag
    42541 tcaaataagt catagacccc atagccgaca tctttttcgt tggttgcctt gaaggctggt
    42601 ggcatccaga cgtgactgat ccccagatga gctaggtgtg gagcattttc agccagacgc
    42661 gtccagtgtt gaccgtcgtg gggcagatac cattcaaagt attgcatgag tgtttgattt
    42721 tgcatgatgt ttcctcttac ttgtcaatct tgttctttat tctatcataa agtatctctc
    42781 ggagcaaacg tttgcgtaag atagaaggaa actattttaa ctacttaaaa taaagtattg
    42841 atttttttgt atcaaagtgc tagtatagcg atatataata cagataaaga taggagtcat
    42901 cccatgattg aatttcaaaa tgttagtaag ttgtatggtg ataaagaggc cttgagtaat
    42961 ctcaatttgc agattgaaaa tggagagatt atgggcttga ttggtcataa tggggctgga
    43021 aaatcgacca ccataaaatc cctagtcagt atcatttcac ccagcagtgg tcgtattttg
    43081 gtagatggtc aggagttatc ggaaaatcgc ttggcgatca aacgaaagat tggctacgta
    43141 gcagactcgc ctgacttatt tttacgttta acggccaatg aattttggga attgatcgcc
    43201 tcatcctatg atctgactag ctctgacttg gagactagtc tagctaggct attgaacgtt
    43261 tttgattttg ctgaaaatcg ttatcaggtt attgaaaccc tttctcatgg aatgcgtcag
    43321 aaagtttttg tcatcggggc actcttgtct gatcctgata tttgggtctt ggacgaaccc
    43381 ttgactggtt tggatcccca ggctgccttt gatttgaaac agatgatgaa ggaacatgca
    43441 caaaaaggga agacggtctt gttttcaact catgtcctag aggtagccga gcaagtctgt
    43501 aatcggattg ccattttgaa aaaggggcat ttgatctatt gtggtagtgt agagaacttg
    43561 aggaaagacc acccagacca gtctttggaa agtatctacc ttagtcttgc tggtagaaaa
    43621 gaggaggttg cggatgcgtc tcaaggtcat taaaaaatta gttgatatca atatcctcta
    43681 ttcatctcaa gaagctaatc tggctaatct acgaaagaag caggctaaga atcctgggaa
    43741 aaaagtaaat gtttccgcta gagtcctaag ttcttacatt ttttctagtc tcttgatgct
    43801 tttcatgttt ataaatatag cctttcgttt tccttttgag gaaatgccaa gtttttttag
    43861 tacgatggtt gctattttac tggtgctggc cttttcaact tctttcactg cattttacaa
    43921 tgtcttttat gagagtaagg acctggcctc ctataggccc tatgccttta aagaatcaga
    43981 gattataatg gccaaaggtc tgtctgtcct cttgccagct ctagctggaa ttgtaccaat
    44041 cctagcttat tttctggtcc tctacattag gctagcacct tctctgtggt tgggtttgcc
    44101 tttgatgcta ctgtccttga ccttattatt tgtctctgtt actttagtga tggtagtggc
    44161 agtacatttc ttggctcaga ctagggtctt cagaaagtat cggtctattt tttcgaatgt
    44221 gatgattggg ataggagttc tcataccttt aatatttatc ttctttcttc agtcgacttt
    44281 tggaagtatt gttgacaaag ttagagacat tccatttctc ctttatcctc ttcatatctt
    44341 ttacaaaata gcagtggagc ctttttcgac agaagcctta gtgggtctgc tcgcttggat
    44401 aggactaact ctcttcctgc tttatctgac caaaaagaag gtccttcctc gtttttatga
    44461 cgtgatcctg cttaatagtg aggataaggt caaaaaagaa cgtcgcagca aggagagaat
    44521 ttcaaccact aaaaagggat tttttcgcat ggttttacgc taccacctca ccctcttggg
    44581 acaggggact ggcgtggtta cagtgctttt tacaagtgct ttctttcctt atctcatgat
    44641 gatcggtctg atttccaaaa tccgagattc tcagatagtt ccagacattc atcctccata
    44701 ctggttaccc ttgtttttta tagctctctt tatagcagtt gtcaataaca atatcaccag
    44761 cctgcattca attgccttgt ccttggagag ggaaaatgtt gattttctta agagtttacc
    44821 ctttgacttt gctcgttatg tgaaagtgaa attttggatt atatatgctg tccagtcctt
    44881 tttaccagtt ctgactttgc ttggtctttc tctatatcta ggcttgccca tcatttcgat
    44941 gatttacctt attgtggcat ggatccttgc cagtgtcatc ctttcttgcc accattactt
    45001 taaggacgtt aaaaatctgt caaccaattg gagtagcatt acggacctgg tgaatcgttc
    45061 aaatggcata gtcgccatag ttttattgtt tatttatagt gcaatcctga tggcccttgt
    45121 aattgggagc atattcttgg ttcagtctct ctccactatc cttgccatca gcttgggagt
    45181 aggagctctt atcctcctgc ttgctcttgc tatttttggc tatcattatt acctgtcacg
    45241 catattggca gaaatagaaa aaagatgagc tggttggtcg cttgcttgat aaattcaatt
    45301 cgacaaacgc ttttatagtt tgttagaatg tagttgtaaa tgattaagat tggtaatcaa
    45361 aaatataggg aggaatgttt tgaataagaa atataacata gttctatttt tgttgtttat
    45421 agtttattta tttggatatt tttcaatttc aaaaacgtta attcctataa tgtgtgtgtt
    45481 ccaagtattc ttgatagaac ata
//
LOCUS       DBERDS010000012        45426 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.012, whole genome shotgun sequence.
ACCESSION   DBERDS010000012 DBERDS010000000
VERSION     DBERDS010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.012"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            171..476
                     /locus_tag="ACL73E_000763"
                     /pseudo
     CDS             171..476
                     /locus_tag="ACL73E_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            608..1552
                     /gene="manA"
                     /locus_tag="ACL73E_000764"
     CDS             608..1552
                     /gene="manA"
                     /locus_tag="ACL73E_000764"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGS0800766.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGIFILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1573..3051)
                     /locus_tag="ACL73E_000765"
     CDS             complement(1573..3051)
                     /locus_tag="ACL73E_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGS0800767.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSAIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFEKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSLWSSLPNLCNQKGLE"
     gene            3156..3905
                     /locus_tag="ACL73E_000766"
     CDS             3156..3905
                     /locus_tag="ACL73E_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGS0800768.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLYTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3925..4380)
                     /locus_tag="ACL73E_000767"
     CDS             complement(3925..4380)
                     /locus_tag="ACL73E_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS0800769.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4400..5574)
                     /locus_tag="ACL73E_000768"
                     /pseudo
     CDS             complement(4400..5574)
                     /locus_tag="ACL73E_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
     gene            complement(5633..6478)
                     /locus_tag="ACL73E_000769"
     CDS             complement(5633..6478)
                     /locus_tag="ACL73E_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0800770.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSIQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            6603..7160
                     /locus_tag="ACL73E_000770"
     CDS             6603..7160
                     /locus_tag="ACL73E_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGS0800771.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7179..7646
                     /locus_tag="ACL73E_000771"
     CDS             7179..7646
                     /locus_tag="ACL73E_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGS0800772.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7735..8364
                     /gene="upp"
                     /locus_tag="ACL73E_000772"
     CDS             7735..8364
                     /gene="upp"
                     /locus_tag="ACL73E_000772"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGS0800773.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8538..9128
                     /gene="clpP"
                     /locus_tag="ACL73E_000773"
     CDS             8538..9128
                     /gene="clpP"
                     /locus_tag="ACL73E_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGS0800774.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9207..9455
                     /locus_tag="ACL73E_000774"
     CDS             9207..9455
                     /locus_tag="ACL73E_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGS0800775.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9557..10717
                     /locus_tag="ACL73E_000775"
     CDS             9557..10717
                     /locus_tag="ACL73E_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0800776.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINGAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10985..11854
                     /locus_tag="ACL73E_000776"
     CDS             10985..11854
                     /locus_tag="ACL73E_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS0800777.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11858..12814
                     /locus_tag="ACL73E_000777"
     CDS             11858..12814
                     /locus_tag="ACL73E_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGS0800778.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12814..13578
                     /locus_tag="ACL73E_000778"
     CDS             12814..13578
                     /locus_tag="ACL73E_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800779.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13578..14288
                     /locus_tag="ACL73E_000779"
     CDS             13578..14288
                     /locus_tag="ACL73E_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800780.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14596..15252
                     /locus_tag="ACL73E_000780"
     CDS             14596..15252
                     /locus_tag="ACL73E_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGS0800781.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15359..16454
                     /gene="prfB"
                     /locus_tag="ACL73E_000781"
     CDS             join(15359..15430,15432..16454)
                     /gene="prfB"
                     /locus_tag="ACL73E_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGS0800782.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16472..17164
                     /gene="ftsE"
                     /locus_tag="ACL73E_000782"
     CDS             16472..17164
                     /gene="ftsE"
                     /locus_tag="ACL73E_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGS0800783.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17157..18083
                     /gene="ftsX"
                     /locus_tag="ACL73E_000783"
     CDS             17157..18083
                     /gene="ftsX"
                     /locus_tag="ACL73E_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGS0800784.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSAVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18351..20531
                     /locus_tag="ACL73E_000784"
     CDS             18351..20531
                     /locus_tag="ACL73E_000784"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGS0800785.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20583..21398
                     /locus_tag="ACL73E_000785"
     CDS             20583..21398
                     /locus_tag="ACL73E_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGS0800786.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            21538..22881
                     /locus_tag="ACL73E_000786"
     CDS             21538..22881
                     /locus_tag="ACL73E_000786"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0800787.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLEIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23096..24286
                     /gene="metK"
                     /locus_tag="ACL73E_000787"
     CDS             23096..24286
                     /gene="metK"
                     /locus_tag="ACL73E_000787"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGS0800788.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24721..25656
                     /locus_tag="ACL73E_000788"
     CDS             24721..25656
                     /locus_tag="ACL73E_000788"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGS0800789.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIKELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25690..26727
                     /gene="holA"
                     /locus_tag="ACL73E_000789"
     CDS             25690..26727
                     /gene="holA"
                     /locus_tag="ACL73E_000789"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGS0800790.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKVDSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            26900..27505
                     /gene="sodA"
                     /locus_tag="ACL73E_000790"
     CDS             26900..27505
                     /gene="sodA"
                     /locus_tag="ACL73E_000790"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGS0800791.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27662..28192
                     /locus_tag="ACL73E_000791"
     CDS             27662..28192
                     /locus_tag="ACL73E_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGS0800792.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISCLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SHKEDKGQRHFVIRQK"
     gene            28213..29298
                     /gene="rlmN"
                     /locus_tag="ACL73E_000792"
     CDS             28213..29298
                     /gene="rlmN"
                     /locus_tag="ACL73E_000792"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGS0800793.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVDCNIGCTFCASDLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITVSTSGLAHKIRNFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEYGT
                     DIDAACGQLRSNTMKRDRQKAVAEVNP"
     gene            29300..29773
                     /locus_tag="ACL73E_000793"
     CDS             29300..29773
                     /locus_tag="ACL73E_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGS0800794.1"
                     /translation="MTKKRELILRLGVAVYSLCIVYFCFTPQATVEVGTPGIQHLGRL
                     VFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKKVLL
                     FSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN"
     gene            29775..31316
                     /locus_tag="ACL73E_000794"
     CDS             29775..31316
                     /locus_tag="ACL73E_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0800795.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMTEDGADVDALMEEVGELQDRLESRDFYILDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKSLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31372..32175)
                     /locus_tag="ACL73E_000795"
     CDS             complement(31372..32175)
                     /locus_tag="ACL73E_000795"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGS0800796.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNHALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32258..32470)
                     /locus_tag="ACL73E_000796"
     CDS             complement(32258..32470)
                     /locus_tag="ACL73E_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800797.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(32950..33159)
                     /locus_tag="ACL73E_000797"
     CDS             complement(32950..33159)
                     /locus_tag="ACL73E_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800798.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            33329..33601
                     /gene="rpsP"
                     /locus_tag="ACL73E_000798"
     CDS             33329..33601
                     /gene="rpsP"
                     /locus_tag="ACL73E_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGS0800799.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33621..33860
                     /gene="kphA"
                     /locus_tag="ACL73E_000799"
     CDS             33621..33860
                     /gene="kphA"
                     /locus_tag="ACL73E_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGS0800800.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34009..34333
                     /locus_tag="ACL73E_000800"
                     /pseudo
     CDS             34009..34333
                     /locus_tag="ACL73E_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            34437..35225
                     /locus_tag="ACL73E_000801"
     CDS             34437..35225
                     /locus_tag="ACL73E_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0800801.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            35256..35774
                     /gene="rimM"
                     /locus_tag="ACL73E_000802"
     CDS             35256..35774
                     /gene="rimM"
                     /locus_tag="ACL73E_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGS0800802.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35764..36483
                     /gene="trmD"
                     /locus_tag="ACL73E_000803"
     CDS             35764..36483
                     /gene="trmD"
                     /locus_tag="ACL73E_000803"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGS0800803.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36495..36833
                     /locus_tag="ACL73E_000804"
     CDS             36495..36833
                     /locus_tag="ACL73E_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGS0800804.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(36863..37183)
                     /locus_tag="ACL73E_000805"
     CDS             complement(36863..37183)
                     /locus_tag="ACL73E_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800805.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37281..37496
                     /locus_tag="ACL73E_000806"
     CDS             37281..37496
                     /locus_tag="ACL73E_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGS0800806.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37493..37681)
                     /locus_tag="ACL73E_000807"
     CDS             complement(37493..37681)
                     /locus_tag="ACL73E_000807"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800807.1"
                     /translation="MTQYPFFYFENLYSMKIKEQTRKLAAGCSKHCFEVVDETDEVSN
                     HTYGKAKLMRFEEIFEEY"
     gene            complement(37701..38237)
                     /locus_tag="ACL73E_000808"
     CDS             complement(37701..38237)
                     /locus_tag="ACL73E_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGS0800808.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQTYFTN"
     gene            complement(38433..39779)
                     /gene="gor"
                     /locus_tag="ACL73E_000809"
     CDS             complement(38433..39779)
                     /gene="gor"
                     /locus_tag="ACL73E_000809"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGS0800809.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            40065..41264
                     /locus_tag="ACL73E_000810"
     CDS             40065..41264
                     /locus_tag="ACL73E_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGS0800810.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVANEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            41248..41949
                     /locus_tag="ACL73E_000811"
     CDS             41248..41949
                     /locus_tag="ACL73E_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800811.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            41951..43210
                     /locus_tag="ACL73E_000812"
     CDS             41951..43210
                     /locus_tag="ACL73E_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0800812.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            43334..45331
                     /gene="metG"
                     /locus_tag="ACL73E_000813"
     CDS             43334..45331
                     /gene="metG"
                     /locus_tag="ACL73E_000813"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGS0800813.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFCLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        13897 a         8410 c         9907 g        13212 t
ORIGIN      
        1 cctgatcgat ttgccctgtt cttgtttcgt tttactatag aacgatttga aggcgtttat
       61 gatatttagc tgtacgagag tctttaaaaa gtgttttgat ggtttggatt tcttctttag
      121 ttgatttcat atcactatta tataatgctt tttgatttta gtatagtatt atcgtagaaa
      181 atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat gactatcgga
      241 ttacttactt agaggcccac atcaaggcca tgcgagatgc catttacaaa gacggggttg
      301 acttgcttgg ttatacgaca tggggctgta tcgattcggt ttcagctggc acaggggaaa
      361 tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat gggactctca
      421 aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg gtgtaagcat
      481 cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt ataagatgta
      541 aaaaagagtt caattcgaac tctttttttg ctataatgag gggagaaaaa tcagacagga
      601 gatcgacatg tcagaaccat tatttttaca atcagttatg caagaaaaaa tctggggtgg
      661 agccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaaatcg gagaatattg
      721 ggccatctca gcccatccaa atggagtctc taaagttgcc aatggtcgtt acgagggaac
      781 agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc cagaacctgt
      841 atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc aagttcaccc
      901 agacgatgct tatggactcg agcatgaagg cgaactcgga aaaacagaat gctggtacat
      961 tatcgcagcg gatgaaggtt cagagattat ctacggtcac aatgccaagt caaaagaaga
     1021 actccgccag caaatcgagg acaagaactg ggatgacttg ttgaccaaag tccctgttaa
     1081 ggctggagat ttcttctatg taccaagcgg gactatgcac gctatcgggg cgggtatctt
     1141 catccttgaa acccagcagt ctagcgatac cacctatcgc gtctatgact ttgaccgcaa
     1201 ggatgacaaa ggcaacttgc gtgaacttca tcttgaaaaa tccatcgatg tcttgaacat
     1261 tggtgagcca gcaaatagcc gtcctgtaac tgttaaagca gatgatttgc gttccactct
     1321 ccttgtatct aatgatttct tcgcagttta caagtgggaa attactggaa aagttgactt
     1381 tgaaaagaca gctgactaca gcttattgag tgtcttagct ggtcaaggtc agctaactgt
     1441 tgacgggaaa aattatccaa ttcaaaaagg cagccacttt atcctaccaa gtgatgttga
     1501 agcttggact ctggaagggc aaggtttgga attgattgtt agccatccat aaaaagaaag
     1561 ggcctgagtt cactactcaa gtcctttttg attacataaa ttgggcaatg aagaccacaa
     1621 tgatgatgat tggaatgacg gaacgaagaa acgaagaagg aagagccaga cttggaacag
     1681 tccttgtttc catgctcttt catcgagatg gagttcctcc attgcaagag cctttttaaa
     1741 gatatagcct gtaaaaagtg aaaggtagag agctccaaat ggcatgagga gattggaaac
     1801 caagaagtcc atagcgtcaa agaaggtctt accaaaaatg tgaacatccg ccatgacacc
     1861 gtaagatagg gctgaaggaa tgccaaagac aaaggtcaaa attcctaaaa taacactcca
     1921 tttggcacgt ttgctgttat cctggttggt gatattgccc acattgatct ccagcatcac
     1981 gacagaagaa gtgacagtcg caaagaggaa gaggacgtag aaaatggttc caaaaggcat
     2041 cttgtcaaag agttgaggca agacgataaa gagcaggctg ggtccccctt cagactggat
     2101 attgaagggg gatcgagctt ggaaaatggc tagacctgcc atgatggata tcgagatatt
     2161 catggctacg atggagattc ctgactggac tagattggtt ttcttgtcca agtaagaagc
     2221 ataggtcaac atgactgtaa cccctagtga gagggcaaag aaagattgtc ccagagcata
     2281 gaggagacca gcgctagtca gttttgaaaa gtctggtttg aggaagtaaa gaaccccttc
     2341 catggcattt ggcaaactga gagagcgacc gatgataaca acaaagatga taaagagcag
     2401 gggcatcatg actttcgaag ctctttcaat ccctttttga accccacgtg atacaatgaa
     2461 gatattcaat aggataaagg ccgcttgagc tcctagggca atggctggat ttgaaatgat
     2521 tgaagtaaat aactgagcat aatcacccgt tccaccaagt tggaacaatt tcccaaactc
     2581 aatacctaga tagactagaa tccatcctcc gataacactg taaaaagata agaggataaa
     2641 gagggcaaag gcgccaatcc aaccgataaa gttgtacttg ttattcttgc ccagtttttc
     2701 aaaggttttg atagcggaaa cgccagcact acggccaagg gcaaactcag ccagcaggag
     2761 agggaaaccg attaaaatag tggaaatgag aaagattagt aaaaagcctc caccgccatt
     2821 agcagcagtc atgtagggaa acttccaaac ggaaccaagc ccgatggccg agccagcaga
     2881 tgctagaata aaaccaagtt tcgaccccca ttgtgatttt tctgacatag ttaaactctg
     2941 atctcctttt tcaaaataag aaaaagctac ttgagttgtc aaatagcctt ctgtttgatt
     3001 gatagacttg actatcctat catgttttct aaggtctgtc aagaaaatca ttttcaagtt
     3061 ttcatacctt tctcaaaaaa gttaaaaaat tttctcaaaa acgcttgact ctgacctaag
     3121 gggaggggtt atactatcat tgtaaggagg aaatcatgta ccatataaaa gaagctgcgc
     3181 agctttcagg tgtctctgtc aagaccctgc atcactatga caagatagga ctcttggtcc
     3241 ccttaaagtc ggaaaacggc tatcgaacct acagtcaaga ggatttggaa cgccttcagg
     3301 tcattcttta ctacaaatat ctaggctttt ctttagagaa aatagcagag ctgttaaagg
     3361 aagaaaggac agatttattg ccccatttga ctaggcagtt ggactatcta actcgcgaaa
     3421 ggcaacatct gtataccttg atttccacct tgcaaaaaac tattcaagaa caaaaaggag
     3481 aaagaaaaat gaccattgag gaaaaattca cgggatttag ctatcaagac aatcaaaaat
     3541 accaccaaga agcggtagag aaatatggtc aagaagtcat gggacaagcg ctcgaacgcc
     3601 aaaaaggtca cgaagacgag gctacggccg cctttaacca agtctttcaa actttggcac
     3661 aaaatcttca agttggttta cctgcaacag caaccgaaaa ccaagagcaa gcagccaagc
     3721 tcttgcaagc cattcgcact tatggatttg actgctctat tgaggtattc ggtcatatcg
     3781 gtaaaggtta cgtctacaac ccagagttta aggaaaacat tgacaagttt ggttctggaa
     3841 cagcccagta cacgtcagat gccattgcag cttacgttca gacaaatgca gaaaaaatag
     3901 gctaggaatt tcctagccta ttttttactt caaatcataa agccagtcgt caccgttttt
     3961 gtagtaaaag aattcactga gatcttcttc tagaaacaca cgaagcatat cagacatatc
     4021 atcggttgca agttttagat gagaaagatt ttcaaagtcc tcccaccaaa ctttcccttc
     4081 gtctgaagac tggagttcac cagtaaagtg ttctgtcttg taaaaaagga cgacataacg
     4141 ataatccttg tcgtcatacc agtttttgat accacagagt tggggtttgg aaatgatcag
     4201 accagtttct tctttcactt cacgaatgac agcatcgaca aaggattcgc cacgttcaac
     4261 atgaccacca ggaaaagtaa tgccaggcca gtcgggacta actcggtctt ggaccaggac
     4321 cttatctccg tttttaatca tacacatgtt aacaaattcg actgcctctc ttctgttcat
     4381 tcttcacaac ctttaatctt taatcataat gcagacttcc cgccacccag ccggtacaga
     4441 gggcagaagt gatgttaaag ccacccgtgt gggcattgat atccataact tcgcctgcaa
     4501 agtggaggcc aggtaccagc ttactttcaa gggttttagg attgatttcc ttgagactga
     4561 ctccaccctt ggtaacaaag gactttgcaa gggacatttt tccagttaca ggaattttaa
     4621 gttctttaat ggactggaca agctgttctc gttccttttc agtcagctgt ttgacttttt
     4681 caggatatcc ttgtacaaaa aattcggcca agcgttctgg taacaaggtt tttaaagcgt
     4741 ttttcaagga tttttcccga ttttttctag aaatgtaacc aagttcttct cagaaagttg
     4801 aggcaaaaca tcgagtgaga gaacctcccc accgtttaca aagctagaca tgcgtagggc
     4861 agcaggacct gacaaaccaa agtgggtaaa gagtaaatca tgagtgatga catgcttacc
     4921 ataacttagg gtcacatcgt ccagagaaat cccttgtaag gctttatgtg gaaaatctgt
     4981 taataaagga ctttcagcag cctcaagatc tgtgatggta tgcttaaaat ggcgagcaat
     5041 ctcgtgacca aaaccagtcg aaccagtcga aggataagac ttaccacctg ttgtgacaat
     5101 gagtttctca caagtgaagg tttgatccgc tgacttaagg acaaactggt catctacttt
     5161 tttaacagaa acgatttcta tttgagtagc aacttgacca cctagttcgg tgattttctt
     5221 ttccaaagct tcgataatag tccgagactt gtcactggct ggaaagacgc gtccgtggtc
     5281 ttcgacctta agtttaacac cattttctgt aaaaaagttg atgatgtcat gattatcgaa
     5341 ctgggagaaa acactgtaaa gaaagcgtcc gtttccagga attccagcta gcaggttgtc
     5401 taagctacca ttgttggtca cattgcaacg tcccccacca gtcccagcta atttttttcc
     5461 aagtttccga tttttttcga tgaggagggt tttctgtcca taaaagctac tggaaatcgt
     5521 agccatcata ccagcaggtc ccccaccgat gacaatagta tcaaaatgtt tcatagctct
     5581 attgtaccac aaaaaaacaa gagatgatgg tcacctcttg tcaagaatgc aattaatcaa
     5641 tttcatagcc catcagcaaa ccgccatctt ctgcatagaa actgcagaga ccagaggttg
     5701 gtagaatttt aatatccgct tgtgggaagg tttcacggat tcgctctgag agctgttgac
     5761 aacatttttc gttattgcgt tgggccatga caatacggcc accagcatat ccagctttta
     5821 ctaactcatc ataggcagct tgaattgatt tctttgatcc ccttgctttt tgtagcaatt
     5881 cgagagttcc agtttcacta gcttttccga ccatacgaat gttgagaagg ccaacgaccg
     5941 taccgataag cttgctcaaa cggccgttct tcaccaagtt atcgactttg gctaggacaa
     6001 agagcaactt agttttttct tgataggcgg tgatagcttc aaccacttct tcaaaagaca
     6061 agccctggtc aatcaagtca ttcaattttt ctacgagtag gtcaacttca ccaccagcag
     6121 ataaactatc aatcacatga atcttagtgt caggatggtc ttccagataa atattctttg
     6181 ctagttgagc actattgtga ctgccagaaa gggtacctgt gatggttact aggaaaatgt
     6241 ttttggcacc ttcaaatgct cgcaaatagt catctgggct tggacaagcc gattttgaag
     6301 cttctgcagt tgcatacatg gtttccatca tttggtcaat atcgagactg gcgtcatcaa
     6361 caaagacctg atcagctact tgaatggtta aggggacgct tacaaaggtt gtgttaatag
     6421 ctggtgttgg cagttgacga taatcacaac cagagtcagc aataatcttc caagtcatag
     6481 aaattctcca tctttgtcag ttatacattg acaaaggttc tgtctttttt tacaattata
     6541 tcatgaaaac ccttgaaaca aaagcatcat ccgtctgttg tgacaagtag aaagaaaatg
     6601 ttatgtctga acgtagaatc tctgaaaagt ctcttgaaaa tctcagaaaa tcaaaccaag
     6661 aatccaattt attaaccaga gaagccattg aaacagccct cttgcaactc ttggaaaaaa
     6721 aggaactgac caagattagt atttctgaat tggtcaaacg tgcaggtgtt tcgcgtgcgg
     6781 ccttttatcg caattatgac tccaaagagg aaattttaga gagcgtcttt aaacgaactg
     6841 tccacaatat tatggaacag ctgcatcatt acgatttaaa gacagacctt tatttggttt
     6901 gggttcacct tttccgggag gccagaaagg aagctagagt aattcaattg gccttggatt
     6961 accatctgga aaaaatcttt gtccaagcca tgcaggaatt tctagaaaaa taccatggga
     7021 aatcaaaagg tgtcagctct tatcttcatt ccttctggag ctcagccatc gtctctgtcc
     7081 ttctaaaatg gatcaaggat ggcatgaagg taccagctga aaagattgca gatttaggtt
     7141 taccattttt taaaaaatag agaaaaagga gaaaagagat gactgaaaaa agactggcct
     7201 gggatgagta ttttgcagcc caagccctac taattgcgaa tcgttccact tgtaaacgtg
     7261 ctaaagtggg cgcgattctg gtaaaagata ataaggttat ttccactggt tacaatggtt
     7321 cggtgtcagg gactgagcat tgtattgatc acgaatgttt ggtcattgaa ggccactgtg
     7381 ttcgcaccct tcacgctgag gtcaatgcta tccttcaagg tgctgagcgt ggtgttccca
     7441 aaggctttac agcctatgta acccattttc cttgtctcaa ctgtacaaaa caattgcttc
     7501 aggtcggctg caagcgtgtg gtttatatca accagtaccg aatggacgac tacgcccaat
     7561 acctttatca agaaaaaggg acagaattga cccatttacc acttgagaca gtacagacag
     7621 ctcttaaaga ggctgatcta atgtaaaaat tatcaaaaat aaatggttta gaaagatttt
     7681 taaaccgttt tttggtataa taagaagaat aaattgaaag aaggaattcc aaaaatggga
     7741 aaaattgaag ttattaatca cccactgatt caacacaaat tgtcaatctt gcgtcgtaca
     7801 gatacttcta caaaagcttt tcgtgagcta gtagatgaga ttgcaatgtt gatggggtat
     7861 gaagtacttc gtgatcttcc actagaagat gtggaaatcg aaacaccaat tacaaaaaca
     7921 gttcaaaaac aattggcagg taagaaattg gccatcgtcc caatcttgcg tgcaggtatc
     7981 gggatggttg atggtctctt gagcttggtt ccagctgcta aagttggcca catcggtatg
     8041 taccgtgatg aagaaacact tcaaccagtt gaatacttgg tgaaattgcc tgaggacatt
     8101 gaccaacgtc aaatttttgt agtagaccca atgttggcaa caggtggctc agcaatcttg
     8161 gctgttgatt ctcttaaaaa acgtggcgca tcaaatatca aatttgtctg ccttgtatct
     8221 gctccagagg gtgtaaaagc ccttcaagaa gctcatccag atgtagaaat ctttacagca
     8281 gccttggatg aacgtttgaa cgaacacggt tatatcgttc caggtcttgg agatgctgga
     8341 gaccgcttgt tcggtacaaa ataagatcga aaagaagaat gacttggaaa agtatttcca
     8401 gtcacgaaag gaggttgggt ttttgtttct gtctaatgaa agcagagcaa aaatttgacc
     8461 ttttttgacc aagatattat aatagtctta tcttcagtca tttgaccaac aaaattaaaa
     8521 ctcaaaagga gaaatgaatg attcctgtag ttattgaaca aacaagccgt ggagaacgtt
     8581 cttacgatat ttactcacgt cttctcaaag accgcatcat tatgctgaca ggtccggttg
     8641 aagacaatat ggctaactct gttattgccc aactgctttt cttggatgcc caagatagta
     8701 caaaagatat ttacctttat gtcaatacac caggtggttc tgtttcagct ggtttggcaa
     8761 tcgtagatac catgaacttt atcaaggcag atgtccaaac cattgttatg ggaatggctg
     8821 catctatggg aacagtcatc gcatcaagtg gagcaaaagg caaacgtttc atgcttccaa
     8881 atgctgaata catgattcac caaccaatgg gcggtacagg tggtggtacc caacaaactg
     8941 atatggctat cgctgcagaa cacttgctca aaactcgtaa taccttggaa aaaatcttgg
     9001 ctgaaaattc aggtcagtca atggaaaaag tccatgcaga tgcagaacgt gataactgga
     9061 tgagcgccca ggaaacactt gaatatggct ttattgatga aattatggcc aacaattcat
     9121 tgaactaatg atgatagaag gcaaactcga ctgggtttgc tttttttggt ataataggga
     9181 gagatttctt agaaagagga tttatcatgt ttgaaaaagt caatcgctct ggcttgatta
     9241 tctatcttta ctataatcgt gatgccaaaa aactgcagga ttatggagat attacctatc
     9301 attccaagaa acatcgttac ttacaactct atgttccaac tcaagaagtg gagcaattgg
     9361 tcggacgctt gagcaaggaa aaatttatta aaaaagttag ggtttgtcat atccaagagt
     9421 tggaaacacc ctttgtgggc aatctttatc gataggaaaa cgttatcatc gaaaaagttc
     9481 aaggaaaaca ttgacaattt tctgataatt cggtatattc ttaacagact atttaagaaa
     9541 taaggagaca aaaaagatga agaaaaaatt tgccctatcg tttgtggcgc ttgcaagtgt
     9601 agcacttctt gcagcctgtg gagaagtgaa gtctggagca gtcaacactg ctggtaactc
     9661 agtagaggaa aagacaatta aaatcgggtt taactttgaa gaatcaggtt ctttagctgc
     9721 atacggaaca gctgaacaaa aaggtgccca attggctgtt gatgaaatca atggcgcagg
     9781 tggtatcgat ggaaaacaaa tcgaagtagt cgataaagat aataagtctg aaacagctga
     9841 ggctgcttca gttacaacta accttgtaac ccaatctaaa gtatcagcag tcgtaggacc
     9901 tgcgacatct ggtgcgactg cagctgcggt agcgaatgct acaaaagcag gtgttccatt
     9961 gatctcacca agtgcgactc aagatggatt gactaaaggt caagattacc tctttattgg
    10021 aactttccaa gatagcttcc aaggaaaaat tatctcaaac tatgtttctg aaaaattaaa
    10081 tgctaagaaa gttgttcttt acactgacaa tgccagtgac tatgctaaag ggattgccaa
    10141 atctttccgc gagtcataca agggtgaaat cgttgcagat gaaactttcg tagcaggtga
    10201 cacagacttc caagcagccc ttacaaaaat gaaagggaaa gactttgatg ctatcgttgt
    10261 tcctggttac tataatgagg ctggtaagat tgtaaaccaa gcgcgtggta tgggaattga
    10321 caaaccaatc gttggtggtg atggattcaa cggtgaggag tttgtacaac aagcaactgc
    10381 tgaaaaagca tcaaacatct actttatctc aggcttctca actactgtag aagtttcagc
    10441 taaagctaaa gccttccttg acgcttaccg tgctaagtac aatgaagagc cttcaacatt
    10501 tgcagccttg gcttatgatt cagttcacct tgtagcaaac gcagcaaaag gtgctaaaaa
    10561 ttcaggtgaa atcaagaata accttgctaa aacaaaagat tttgaaggtg taactggtca
    10621 aacaagcttc gatgcagacc acaacacagt caaaactgct tacatgatga ccatgaacaa
    10681 tggtaaagtt gaagcagcag aagttgtaaa accataatag aaaaatgttg aaacagggaa
    10741 tgagcctttg actcactccc tgtttcgata tttaatactc ttcgaaaatc tcttcaaact
    10801 gcgtcaacgt cgccttggat tatatatgtg actgacttcg tcagtcttat ctacaacctc
    10861 aaagcagtgc tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga
    10921 gtataagaac ctatcaaaaa gtgagggaaa accctcggaa ttataaatag aaagagtgaa
    10981 tcttatgctc caacaactcg taaatggttt gattctaggt agtgtttacg cgctgttagc
    11041 cctaggatat accatggttt acggaattat caagctcatc aacttcgccc atggtgatat
    11101 ttatatgatg ggagccttta tcggttattt cttgatcaat tctttccaaa tgaatttctt
    11161 tgtagcgctt attgtagcta tgctagcgac agctattctt ggtgtcgtga ttgagtttct
    11221 tgcttaccga cctttgcgcc actctactcg tattgctgtt ttgattacgg ctattggggt
    11281 ttctttccta ttggagtatg gaatggtcta tctggttggt gccaataccc gtgccttccc
    11341 tcaagcgatt caaacagttc gatatgattt gggaccaatt agcttaacaa atgtgcagtt
    11401 aatgattttg ggcatttcct tgattttgat gattttgtta caagtcattg tccaaaagac
    11461 taagatgggg aaagccatgc gtgcagtatc agtagatagc gacgcggcgc aattgatggg
    11521 gatcaatgta aaccgtacga ttagctttac cttcgctttg ggttctgctc ttgcgggtgc
    11581 ggctggtgtt ctgattgctc tttattataa ctctcttgag cctttgatgg gggttactcc
    11641 aggtcttaaa tctttcgttg ccgcagtact tggtggtatc ggaattattc ctggtgcggc
    11701 tcttggtggc tttgtgattg gtctattgga aacctttgcg acagcctttg ggatgtcaga
    11761 tttccgtgat gccattgttt atggaatctt gttgttgatc ttgattgtcc gcccagctgg
    11821 tatccttggt aagaatgtga aagagaaggt gtaaacgatg aaggaaaatt taaaagttaa
    11881 tattctatgg ttactccttt tgttagctgg ctatagcttg attagtgtac tggtttcagt
    11941 cggagtactt aatctattct atgtacagat tttacaacaa attggaatta atattatttt
    12001 ggctgttggt ctcaacttaa tcgttggttt ttcaggacaa ttttcacttg gtcatgctgg
    12061 tttcatggcg attggtgcct atgcagcagc tattattggt tctaaatcac caacctacgg
    12121 tgccttcttt ggagctatgc ttgtaggggc tttgctttca ggagcagttg ccttacttgt
    12181 cggcattcca accttgcgct tgaaggggga ctatcttgcg gtagcaactc tgggtgtttc
    12241 tgaaattatc cgtatcttta tcatcaatgg tggaagtctt acaaatggtg cggcaggtat
    12301 cttagggatt cctaacttta caacttggca aatggtttac ttctttgtcg tgattacaac
    12361 cattgcaacc ttgaacttct tgcgtagccc aattggccgt tcaaccctct ctgttcgtga
    12421 agatgaaatc gctgctgagt cagttggggt taatacgact aaaattaaaa tcatcgcttt
    12481 tgtctttggt gccattactg caagtattgc tgggtcactt caggcaggat ttatcgggtc
    12541 tgttgtaccg aaagattaca ccttcatcaa ctcaatcaac gttttgatta ttgttgtatt
    12601 tggtggactc ggttccatta caggtgcgat tgtttcggct attgttctgg gaattttgaa
    12661 tatgcttctc caagatgttg ctagtgtgcg tatgattatt tacgctttgg ccttggtatt
    12721 ggtaatgatt ttcagaccag gtggactcct tggaacgtgg gaactgagcc tatcacgttt
    12781 ctttaaaaaa tctaagaagg aggaacaaaa ctaatggcat tacttgaagt aaaacagtta
    12841 accaaacatt ttggtggtct aacagctgtt ggagatgtga ctcttgaatt gaacgaaggg
    12901 gaactggttg gattaatcgg tccaaacgga gctgggaaaa ccaccctttt caaccttttg
    12961 accggtgttt atgaaccaag tgagggaaca gtaaccctag atggtcacct tttgaatggg
    13021 aaatcacctt ataagattgc ctctttggga cttggacgta ctttccaaaa tatccgtctt
    13081 tttaaagatt taacagtttt agacaatgtt ttgattgctt ttggaaacca tcacaaacag
    13141 catgttttta ctagtttctt acgcttacca gctttttaca agagtgaaaa agaattaaag
    13201 gctaaagctt tggaattgtt gaaaatcttt gatttagatg gtgatgcaga gactcttgct
    13261 aaaaatcttt cctacggaca acaacgtcgt ttggaaattg ttcgtgccct tgctacggaa
    13321 cctaaaattc tcttcttaga tgaaccagca gcaggtatga acccacagga aacagccgaa
    13381 ttgactgagt taattcgtcg tatcaaagat gagtttaaga ttacaatcat gttgattgaa
    13441 cacgatatga atctggtcat ggaagtaaca gaacgtatct acgtacttga atatggccgt
    13501 ttaatcgctc aaggaactcc agacgaaatt aagaccaata aacgcgttat cgaagcttat
    13561 ctaggaggtg aagcctaatg tctatgttaa aagttgaaaa tctttctgtg cattacggta
    13621 tgatccaagc agttcgtgat gtaagctttg aagttaatga aggagaagtt gtttccctta
    13681 tcggtgccaa cggtgcaggt aagacaacta ttcttcgcac cttgtcaggt ttggttcgac
    13741 caagttcagg aaagattgaa tttttaggtc aagaaatcca aaaaatgcca gctcagaaaa
    13801 tcgtggcaag tggtctttca caagttccag aaggacgcca cgtctttcct ggcttgactg
    13861 ttatggaaaa tcttgaaatg ggagctttct taaagaaaaa tcgtgaagaa aatcaagcta
    13921 acttgaagaa ggttttctca cgctttcctc gtcttgaaga acggaagaac caagatgcag
    13981 ccactctttc agggggggaa caacaaatgc ttgccatggg acgcgccctc atgtcaacac
    14041 caaaacttct tcttttagat gaaccatcaa tgggacttgc cccaatcttt atccaagaaa
    14101 tttttgatat cattcaagat attcagaagc aaggaacaac ggtcctcttg attgaacaaa
    14161 atgccaataa agcacttgca atctctgacc gaggatatgt actggaaaca gggaaaatcg
    14221 tcctatcagg aacaggaaaa gaactcgctt catcagaaga agtcagaaaa gcatatctag
    14281 gtggctaaaa caatccagtg gattgtttta gtcggcagat ggagattacg aagtaatcat
    14341 caatatagtc cgggggacct ttttagtcgg tagattgaga ttgcaaacaa atctgcatct
    14401 acattgaaag cttaatttct aataattgaa aaaatcgaat gaaaaatttc ttaccttcat
    14461 tcacagagct cgatttcaga gctctttttg ctagcttatt catacttttt tgaatttcga
    14521 aaaagaaatg taagcgtttg atagatttac aaaaagattg tataatgggg ataagaatag
    14581 aaaaggagaa gtctcatggc agttaaagat tttatgaccc gcaaggtagt ttatattagt
    14641 ccagatacaa cagtatctca tgcagcagat ttgatgagag agcaaggatt gcaccgcttg
    14701 cctgttatcg aaaatgatca attggttggt ttggtgactg agggaaccat tgcacaagca
    14761 agtccatcta aagcaacaag tctttctatc tatgagatga attatcttct gaataagaca
    14821 aaagtaaaag atgtcatgat tcgcgatgtt gtcactgtct caggctatgc tagtctagaa
    14881 gatgcaactt atctgatgtt gaaaaataag attggtattc tccctgtcgt agataaccat
    14941 caagtatacg gagttattac tgaccgtgac gttttccaag cctttcttga aattgcaggt
    15001 tatggcgaag aagggattcg tgtacgcttt gttacagaag atgaagttgg tgttcttgga
    15061 aaaattattt ctttgattgt agaagaaaat ttgaatatat cccatacagt caatattccg
    15121 cgtaaggatg gtaaggtcat tatcgaagtg caaatcgatg gatcaattga tttaccagcc
    15181 ttgaaagaaa aatttgaagc aaatggtatt caagtggaag aaatcgctcg cacttcagca
    15241 aaagtcttgt aagaagggaa gccaaaggct tcttttttca tgaaaagggg attagagcaa
    15301 aagatggaaa gaaatgataa aatatgctat aatgaaataa tgtaaaaaag gagtatttat
    15361 ggacatttca gtaattcgtc agaaaattga cgcaaatcgt gaaaaattag cttctttcag
    15421 ggggtctctt tgacctcgaa gggctagagg aagagattgc catcttggaa aacaagatga
    15481 cagaacctga tttttggaac gataatattg cggcccaaaa aacgtcgcaa gaattgaatg
    15541 aattaaaaaa cacttacaat accttccata agatggaaga gttgcaggat gaagtcgaaa
    15601 ttttattgga ttttttggct gaagacgagt cagtgcatga tgaactggta gcgcagttag
    15661 ccgaacttga taagataatg actagttacg agatgactct actcttgtca gaaccttatg
    15721 accacaacaa tgccatcttg gaaatccatc caggttctgg tggtactgag gcgcaggact
    15781 ggggtgatat gttgcttcgt atgtatactc gttatggtaa tgctaaaggc tttaaagtgg
    15841 aagtgttgga ttaccaagca ggtgatgagg ctggtattaa gtcggtaact ttatcatttg
    15901 aagggcctaa tgcctatggt ctcctcaagt cagaaatggg tgttcatcgc ttagtgcgaa
    15961 tctcaccatt tgactctgcc aaacgtcgcc atacctcttt cacatctgta gaagtgatgc
    16021 cagaattgga tgatactatt gaagtggaaa tccgtgaaga tgatatcaag atggatacct
    16081 tccgttcagg tggtgccggt ggacaaaacg tcaataaagt ttcaacaggt gtacgtttaa
    16141 cccacattcc aactggaatt gttgtccaat caacagtgga tcgtacccag tatggaaata
    16201 gagatcgtgc catgaagatg ttgcaggcta agctctatca aatggagcaa gataagaagg
    16261 ctgcggaggt agattctctc aaaggtgaga aaaaggagat cacttgggga agccaaatcc
    16321 gttcttatgt cttcacgcct tatactatgg taaaagatca ccgaactagc tttgaggttg
    16381 ctcaggtaga taaggttatg gatggggacc tagatggttt tatcgatgct tatctcaagt
    16441 ggcgaattag ctaagataga aaggaactca catgtcaatt attgaaatga gagatgtcgt
    16501 taaaaaatac gacaacggaa cgactgctct acgcggtgtt tcggttagcg ttcaaccggg
    16561 ggaatttgcc tacatcgtag gaccttcagg agcagggaag tcaactttta ttcgttctct
    16621 gtatcgtgaa gtaaaaatcg ataaaggaag cctatcagtt gctggtttta atctggttaa
    16681 gatcaaaaag aaagatgtcc cgcttctacg tcgtagtgtt ggggttgtct tccaggatta
    16741 taaactgtta ccaaagaaaa ctgtctatga aaatattgct tacgctatgg aagtaatcgg
    16801 ggaaaatcgc cgtaatatca aaagacgagt gatggaagtt ttggacttgg ttggattgaa
    16861 gcataaggtt cgttcttttc caaatgaact ctcaggtggg gagcagcagc ggattgcgat
    16921 tgcgcgtgca attgtaaata atcccaaagt attgatagct gatgagccaa caggaaatct
    16981 ggatccggat aattcatggg aaattatgaa tctcttggaa cggattaacc tacaaggaac
    17041 aactattttg atggcgactc ataatagcca gattgtaaat accttgcgcc accgtgtcat
    17101 tgccattgaa aatggccgtg tcgttcgtga cgaatcaaaa ggagagtatg gatacgatga
    17161 ttagtagatt ttttcgccat ttatttgaag ccttaaaaag tttgaaacga aatggttgga
    17221 tgacagtagc tgctgtcagt tcagtcatga ttactttgac cttggtggca atatttgcat
    17281 ctgttatttt caatacagcg aaactagcta cagatattga aaataatgtc cgtgtagtag
    17341 tttatatccg aaaggatgtg gaagataata gtcagacaat tgaaaaagaa ggtcaaactg
    17401 ttacaaataa tgactaccac aaggtatatg attctttgaa gaacatgtct gcggttaaaa
    17461 gtgttacctt ttcaagtaaa gaagaacaat atgaaaaatt aaccgagata atgggagata
    17521 actggaaaat ctttgaagga gatgccaatc ctctctatga tgcttatatt gtagaggcaa
    17581 acactccaaa tgatgtaaaa actatagccg aagatgctaa aaaaattgaa ggtgtctctg
    17641 aggttcaaga tggcggtgcc aatacagaaa gactcttcaa gttagcttca tttatccgtg
    17701 tttggggact agggattgct gctttgttaa tttttatcgc agttttcttg atttcaaata
    17761 ccattcgtat taccattatt tcccgcagtc gcgaaattca aatcatgcgc ttggtcggag
    17821 ctaaaaacag ttatatccgt ggaccgttct tgttagaagg agcctttatc ggtttattgg
    17881 gagctatcgc accatctgtt ttggtcttta ttgtttatca aattgtttac caatctgtca
    17941 acaaatcgtt ggtagggcaa aatctatcca tgattagtcc agatttattt agtccgttga
    18001 tgattgccct actatttgtg attggggttt tcattggttc attgggatca ggaatatcca
    18061 tgcgccgatt cttgaagatt taggtaaaat agctgctttt atgaggagat tgtaaaatct
    18121 ccttttttgc tacaagagtt tttgaaaaga gattccaaag aagtccccca gagaagactt
    18181 cttgatggct aatttgaact tgaaatttgg cgcactagaa attttttaga aaaaagtgta
    18241 atttttttat aaaagccttt acaaaaaaaa ttaaagtggt ataattaaat catagaaagt
    18301 gcaaacgttt tcgtaaaacg tttgcctaaa taaaaataaa ggagatttga atgatgaaag
    18361 atacattcaa aaatgtcttg tctttcgaat tttggcaaaa attcggtaag gctttgatgg
    18421 tagttatcgc ggttatgccg gctgctggtt tgatgatttc aatcggtaag tctatcgtga
    18481 tgattaaccc aacctttgca ccacttgtca tcacaggtgg aattcttgag caaatcggtt
    18541 ggggggttat cggtaacctt catattttgt ttgccctagc cattggagga agctgggcta
    18601 aagaacgtgc tggtggtgct ttcgccgctg gtcttgcctt catcttgatt aaccgtatca
    18661 ctggtacaat ctttggtgta tcaggcgata tgttgaaaaa tccagatgct atggtaacta
    18721 ctttctttgg tggttcaatc aaagttgctg attactttat cagtgttctt gaagctccag
    18781 ccttgaacat gggggtattc gtagggatta tctcaggttt tgtaggggca actgcttaca
    18841 acaaatacta caacttccgt aaacttcctg atgcactttc attcttcaac gggaaacgtt
    18901 tcgtaccatt tgtagttatt cttcgttcag caatcgctgc aattctactt gctgctttct
    18961 ggccagtagt tcaaacaggt atcaataatt tcggtatctg gattgccaac tcacaagaaa
    19021 ctgctccaat tcttgcacca ttcttgtatg gtactttgga acgtttgctc ttgccatttg
    19081 gtcttcacca catgttgact atcccaatga actacacagc tcttggtggt acttatgaca
    19141 ttttaactgg tgcagctaaa ggtactcaag tattcggtca agacccacta tggcttgcat
    19201 gggtaacaga ccttgtaaac cttaaaggta ctgatgctag tcaataccaa cacttgttag
    19261 atacagtaca tccagctcgt ttcaaagttg gacaaatgat cggttcattc ggtatcttga
    19321 tgggtgtgat tgttgctatc taccgtaatg ttgatgctga caagaaacat aaatacaaag
    19381 gtatgatgat tgcaacagct cttgcaacat tcttgacagg ggttactgaa ccaatcgaat
    19441 acatgttcat gttcatcgca acacctatgt atcttgttta ctcacttgtt caaggtgctg
    19501 ccttcgctat ggctgacgtc gtaaacctac gtatgcactc attcggttca atcgagttct
    19561 tgactcgtac acctattgca atcagtgctg gtattggtat ggatatcgtt aacttcgttt
    19621 gggtaactgt tctctttgct gtaatcatgt actttatcgc aaacttcatg attcaaaaat
    19681 tcaactacgc aactccaggg cgtaacggaa actacgaaac tgctgaaggt tcagaagaaa
    19741 ccagcagcga agtgaaagtt gcagcaggct ctcaagctgt aaacattatc aaccttcttg
    19801 gtggacgtgt aaacatcgtt gatgttgatg catgtatgac tcgtcttcgt gtaactgtta
    19861 aagatgcaga taaagtagga aatgcagagc aatggaaagc agaaggagct atgggtcttg
    19921 tgatgaaagg acaaggggtt caagctatct acggtccaaa agctgacatt ttgaaatctg
    19981 atatccaaga tatccttgat tcaggtgaaa tcattcctga aactcttcca agccaaatga
    20041 ctgaagcaca acaaaacact gttcacttca aagatcttac tgaggaagtt tactcagtag
    20101 cagacggtca agttgttgct ttggaacaag taaaggatcc agtatttgct caaaaaatga
    20161 tgggtgatgg atttgcagta gaacctgcaa atggaaacat tgtatctcca gtttcaggta
    20221 ctgtatcaag catcttccca acaaaacatg cttttggtat tgtgacggaa gcaggtcttg
    20281 aagtattggt tcacattggt ttggacacag taagtcttga aggtaaacca tttacagttc
    20341 atgttgctga aggacaaaaa gttgcagcag gagatctcct tgtcacagct gacttggatg
    20401 ctatccgtgc agcaggacgt gaaacttcaa cagtagttgt cttcacaaat ggtgatgcaa
    20461 ttaaatcagt taaattagaa aaaacaggtt ctcttgcagc taaaacagca gttgctaaag
    20521 tagaattgta atatacttga ggttggaagc tgtattccaa cctcttattt tgggagaaaa
    20581 gaatgaaatt tttaacactc aatactcaca gttggatgga gaaagaagca gaggaaaaat
    20641 tccagatttt gcttgaagat attcttgaaa aggactatga tttgatttgt tttcaagaaa
    20701 tcaatcagga gatgacctcg tcagaggtgg aggttaatga cctttatcaa gctttgccag
    20761 cagctgagcc tattcaccaa gaccattatg ttagactctt ggttgaaaag ttgttagagc
    20821 aagggaaaaa ttactactgg acctgggctt ataaccatat cggctatgac cgctaccacg
    20881 aaggtgtggc tatcttgtct aaaacaccta ttgaagccag agaaattttg gtttcagatg
    20941 tggatgatcc aacagactat catactcgcc gtgttgccct agctgaaact gtagttgatg
    21001 gcaaggagct agcagttgcc agtgttcatc tctcttggtg ggataaaggt ttccaagaag
    21061 aatgggcacg atttgaggct gttttgaaaa aattgaacaa gccactttta ctagctggag
    21121 attttaacaa cccagcaggt caggaaggtt accaagctat tttagctagt ccattaggct
    21181 tacaagacgc atttgaagtt gctcaagaga aaagtggtag ctatactgtt ccgcctgaaa
    21241 ttgatggctg gaaagggaac actgaacccc ttcgaatcga ttatgtcttt actaccaaag
    21301 agttagcggt ggaaaattta catgtcgtat ttgatggtaa caagagtcca caagtgagtg
    21361 atcactatgg cttgaatgct atgttaaact ggaaataata actgaaaaga ggttggaact
    21421 ataaaattcc agccttttct tactagagaa gctactggaa atagcctaaa taagtgagac
    21481 tactgtaatg gaataaaata tggtataatt gataagatag atagaatcga ggatgttatg
    21541 tcatttacga aatttcaatt taaaaactat attagagaag ccttgaagga gttaaaattt
    21601 acaactccaa cagaggtgca agacaagttg attcctattg ttttggcagg tcgtgaccta
    21661 gtaggagaat caaaaacagg ttcaggtaag actcatactt tcttgttacc gattttccag
    21721 caattagatg aagctagcga tagtgtgcaa gcagtgatta ctgcaccgag tcgtgagttg
    21781 gctactcaaa tttaccaagt agcgcgtcag atttcagctc actcagatgt cgaagttcgt
    21841 gtggttaatt atgtgggtgg tacggataag gctcgccaga ttgagaaatt ggcaagcaat
    21901 cagcctcata ttgttattgg aacaccaggc cgtatctacg acttggttaa atctggtgat
    21961 ttagctattc ataaagccaa gacatttgtt gttgatgaag cagatatgac cttggatatg
    22021 ggattcttgg aaactgttga taagattgct ggcagtcttc caaaagactt gcaattcatg
    22081 gtcttctcag cgactatccc acaaaaactg caaccattct tgaaaaaata cttatcaaat
    22141 cctgttatgg agaaaattaa gaccaaaacg gttatttctg acaccattga taattggttg
    22201 atttcgacca agggacatga taagaatgct caaatttacc agttgactca gttgatgcag
    22261 ccgtatttgg caatgatttt tgttaacact aaaacgcgtg ctgatgaatt gcattcatat
    22321 ctgactgctc aaggcttgaa ggttgcaaaa atccatggag atattgcccc tcgtgaacgc
    22381 aagcgaatca tgaatcaggt gcaaaatctg gattttgagt atattgtcgc aacagatttg
    22441 gcagcgcgtg ggattgacat tgaaggtgtc agccatgtca tcaatgatgc cattccgcaa
    22501 gacttatctt tttttgttca tcgtgttggt cgtactggac gaaatggcct accaggtaca
    22561 gctattaccc tttatcagcc aagtgatgac tcggatatcc gtgagttgga gaaattggaa
    22621 atcaagttta gtcctaagat ggtcaaagac ggggaatttc aagataccta tgaccgtgat
    22681 cgtcgtgcca accgtgagaa aaaacaagat aaacttgata tcgaaatgat tggtttggtt
    22741 aaaaagaaaa agaaaaaagt caaaccgggt tataagaaga aaattcaatg ggcggttgat
    22801 gaaaagcgcc gtaaaaccaa gcgtgctgaa aatcgcgctc gcggtcgtgc agagcgtaaa
    22861 gctaaacgcc aaacatttta atagaaattg ttggagtatt gagctccaac tttttgcttt
    22921 atgagaacga actatctaaa ccgaaacact acattaaaga ctgcaaattg cgattaaaaa
    22981 tggtataatg ataaagttat atagtcccga taagatggta ggtatttatt acgaagagtt
    23041 ttcctatcag tactttgtaa ctctataaca atatttttta aggggggaca tttttatgtc
    23101 agaacgtaaa ttattcacgt ctgaatctgt atctgagggg catccggata agattgcaga
    23161 ccaaatttca gatgcgattt tggatgctat tttagcaaag gatccagagg cgcacgttgc
    23221 tgctgaaaca gctgtatata ctggttctgt ccacgttttt ggtgaaattt ctacaaatgc
    23281 ctatgtggat attaaccgtg tggttcgtga taccattgca gagattggtt ataccaatac
    23341 agaatatgga ttttctgctg agacggtggg agtacaccca tctttggtgg aacaatctcc
    23401 tgacatcgct caaggtgtta acgaagcctt ggaggttcgt ggaaatgctg atcaagatcc
    23461 actggacttg attggagcag gtgaccaagg gctcatgttt ggatttgcag tagatgaaac
    23521 agaagagctc atgccattgc caattgcact cagtcataaa ttggttcgtc gtctggcaga
    23581 acttcgtaag tctggagaaa ttagctatct ccgtccagat gcaaaatcac aagttacagt
    23641 tgagtacgat gaaaatgacc gtccggtacg tgtagataca gtcgttattt ctactcagca
    23701 tgatccagag gccactaatg aacaaatcca tcaagatgtg attgacaagg tcatcaaaga
    23761 agttattcca tcttcttatc ttgatgataa gacaaaattc tttatcaatc cgacaggtcg
    23821 ttttgtaatc ggtggtcctc aaggggactc aggtttgact ggtcgtaaga ttattgtaga
    23881 tacttatggt ggctactctc gtcatggtgg tggtgccttc tctggtaaag atgcgactaa
    23941 ggtggatcgt tcagcctctt atgcggctcg ctatattgcc aagaatatcg ttgcagcaga
    24001 ccttgctaag aaggcagaag tgcagttggc ctatgctatc ggtgttgcgc aacctgtttc
    24061 tgttcgtatc gatactttcg gtacaggaac agtagctgaa agtcaacttg aaaaagcggc
    24121 tcgtcaaatc tttgaccttc gccctgcagg gattatccaa atgctggacc ttaagcgtcc
    24181 aatttaccgt caaacatcgg cttacggtca catgggacgt acagatattg atcttccatg
    24241 ggaacgtttg gataaggtag atgctttgaa agaagcagta aaataagatt ttaagagggg
    24301 aacgtcctct cttttttata gtttttaact atactgggat actgttctga aaatccattt
    24361 tgcgaaagta gagatttaca tgtatagtag attgaaacta aaatagtaca cttgaacttc
    24421 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttctcctgtt cttgtttcat
    24481 tttactatat ttctttaaaa atgataaagg ttgagatttc tccttgttgc ttggacttca
    24541 ttcaaaagtc tgttacccaa gccttgttca aacttccaat acactagctg tttccatagc
    24601 atgacttctg tactagactt tcttttccga ataaatagat agaaccacag aatctagtaa
    24661 acctagaatt aaaattatgg tataatatta gcaataaaag aaatctggag gattagaatc
    24721 atggtatcaa cgaaaacaca aattgctggt tttgagtttg acaattgctt gatgaatgca
    24781 gcaggtgtgg cttgtatgac gataaaggag ttagaagagg tcaaaaactc agcggcagga
    24841 acctttgtta ctaagacagc gaccttggat ttccgtcagg ggaatcctga gccacgctac
    24901 caagatgttc cacttggttc catcaactct atgggcttgc caaataatgg cttagactat
    24961 tatttggatt atcttttaga tttgcaggaa aaagagtcga accgaacttt cttcttatct
    25021 ctggtcggca tgtctccaga ggaaacccat actattttga aaaaagtcca agagagtgat
    25081 tttcgtggtc tgactgagct aaatctttcc tgtccaaatg ttccaggtaa acctcagatt
    25141 gcctatgatt ttgagacaac agaccggatt ttggcagaag tgtttgctta cttcaccaaa
    25201 cctcttggaa ttaaattgcc accttatttt gatattgttc actttgacca agcggcagct
    25261 attttcaaca aatatccgct caagtttgtc aactgcgtta actctatcgg aaacggcctc
    25321 tatatagaag acgagtctgt cgttattcgg cctaagaatg gttttggtgg aattggtgga
    25381 gaatacatca aaccgactgc tctagccaat gttcacgcct tttatcaacg tttaaatcct
    25441 caaatccaaa ttatcggaac aggtggcgtt ctgactggtc gagatgcctt tgaacacatc
    25501 ctctgtggag caagtatggt gcaggtggga acgacccttc acaaagaagg cgtcagtgct
    25561 tttgaccgca ttaccaatga actgaaagca atcatggtgg aaaaaggcta cgagagctta
    25621 gaagatttcc gtgggaaatt gcgctatatt gactaaatta aatcgaaaaa tctgaagaaa
    25681 ggagagacga tgctagccat tgaagaaagt cagaagttga ctttatcaaa tttaccgagc
    25741 ctgagcctat ttacagggac agatcagggt cagtttgaag tgatgaagag tcaaatgttg
    25801 aaacagattg ggtatgattc tgctgacctc aactttgcct actttgatat gaaagaagta
    25861 gtttacaagg atgtggaact ggagttggtc agccttcctt tctttgcgga tgagaaaatc
    25921 gtgatattag attattttat ggatatcacg actgctaaga aacgcttttt gacagatgat
    25981 gagcttaagt catttgagga ataccttgac aatccttctc caacaaccaa gttgataatc
    26041 tttgcagaag gaaagctgga tagcaaaaga cggttagtca aattacttaa gcgtgatgcc
    26101 aaggccttcg atgcagtaga agtaaaagaa caagaattgc gccagtactt ccaaaagtgg
    26161 agtcagaaac aaggtctgca gtttaccaat cattcttttg aaaatctcct catcaagtcg
    26221 gggtttcaat ttagcgaaat ccagaaaaat cttctctttt tacagtccta taaggtggat
    26281 tctgttatcg aggaagagga tattgttaac gcaattccca agaccttgca ggacaatatt
    26341 tttgatttaa ctcagtttat tctgactaaa aagatggatc aggcgcgcga tttggtgaga
    26401 gacttgacct tgcaagggga agatgaaatc aaactgattg cagtcatgct gggacaattt
    26461 cggactttta ctcaggtgaa gattttggcg gagtctggcc aaacagaatc gcagattgca
    26521 agtagtttag gtagttatct gggacgtaac ccaaatcctt accaaatcaa gtttgcatta
    26581 agagattcga gaggactttc tttgagcttt ctgaagcaag ctatttccta tttgattgag
    26641 acagactatc agattaagac aggtctttat gaaaaaggtt tcctttttga aaaggcactc
    26701 ttacagattg ctagtcaggt caattgacat ttgttgaaac tacaacccgc gccaggatta
    26761 tcttgtcgtg ggtttcttgc tgatttgctt attttattag aaagtatgtc agtgatttgc
    26821 ttatctataa gcaaaaaact tgaaaaaagt gaatgtttgc gttatcattt tcatatagaa
    26881 agaaaaagag gtattacaga tggctattat cttaccagaa cttccatatg catacgacgc
    26941 tttggaacca tacatcgatg cggaaacaat gcatttgcac catgacaaac accatcaaac
    27001 ttatgtcaac aatgccaatg cagctttaga aaaacaccct gaaatcggtg aagaccttga
    27061 agccttgctt gctgatgtag aatctatccc agctgatatc cgtcaagcac ttatcaacaa
    27121 tggtggcgga cacttgaacc acgctctttt ctgggaattg atgactcccg agaaaacagc
    27181 tccttcagca gagctggcag cagcaatcga tgcaacattt ggttcatttg aagaattcca
    27241 agcagccttc actgcagcag caacaactcg ttttggttca ggttgggcat ggttggttgt
    27301 caacaaagaa gggaaacttg aagtgacttc aacagcaaac caagacacac caatctcaga
    27361 aggtaaaaaa ccaatcttgg gcttggacgt ttgggaacat gcttactacg tgaaataccg
    27421 caacgtgcgt cctgactaca tcaaagcttt cttttcagta atcaactgga ataaagtaga
    27481 tgaattgtac gcagctgcta aataatgata gttggaggga agaattgttc ttctcttttt
    27541 taggttataa gattctggtc tgacaaaatc gtcagacttt tttcattttt atgagaaacg
    27601 tgctaactgc tagaaattat ggtagaataa agtattaagt aatcgtggaa aaaggatatc
    27661 tatgcgaaaa gaaattgcac ctgaattata caactataac aagtttcctg gtccggagtt
    27721 ccatttacac ggggacaagg tcgaaacgga agggatagct ttttccttgg ttgaaaatat
    27781 caaggatgcc tttgatgtga cgacttttaa tcagcgtttt tcagaagtat taaccaagtt
    27841 tgattatatc gtgggggact ggagcaacga acagcttcgc ctacgaggtt tttacaagga
    27901 tgaccgaaca gaagaaaaac ttgaaaaaat cagttgttta caagactacc ttttagagta
    27961 ttgtagttat ggttgtgcct attttgtctt agaaaatgaa gcccctaagc gagcatcatt
    28021 tgacaagaaa atgcgtaaga cggaagaaga aacaccttct agaaaaggaa agaaaccgac
    28081 tcaaactaaa cgaaagtcga atgcagataa gaaaaataga cgtcgtcaga aagaccagca
    28141 ttctcataaa gaggacaagg gacaacgtca ttttgtcatt cgtcagaagt gagtagagaa
    28201 taaggagaag aaatgaaacc ctcaattcat agtttggcac atcaaaccat gcaggaatgg
    28261 gtattggagc agggagaaaa gaaattccgt gcagatcaaa tctgggaatg gctctaccgt
    28321 aaacgtgtgc agtcatttga agaaatgacc aacctttcca aggatttgat tgctaagctc
    28381 aatgaccagt ttgtggtcaa tcccttgaaa caacgtattg tgcaagagtc tgctgatggt
    28441 acagtcaaat atctctttga attgcctgac ggtatgttaa ttgaaactgt actcatgcgt
    28501 caacactatg gtttatctgt ctgtgtgacc actcaggtcg actgtaatat cggttgtacc
    28561 ttctgtgcct ctgatttgat taagaagcaa cgtgacctca ataacggtga aatcgtagcg
    28621 caaatcatgc tggttcagaa atactttgct gagcgtggtc aggatgaacg cgtcagccat
    28681 atcgttgtca tgggaatcgg tgagcccttt gataattaca acaatgtctt gaatttcgtt
    28741 tgtactatca atgatgataa aggaatggct atcggtgctc gtcacatcac ggtttcaacc
    28801 tcaggtttgg ctcataaaat tcgtaacttt gctgatgaag gggttcaggt caatcttgcc
    28861 gtgtctcttc acgcacccaa caatgaactt cgttcaagta tcatgaagat taaccgtgcc
    28921 tttccgattg aaaaactctt tgctgctatt gaatactaca ttgagacaac aaaccgtcgt
    28981 gtaacctttg aatatatcat gcttaatgaa gtcaacgacg gtgtagaaca agccttggaa
    29041 ttggctgaat tgctcaagaa catcaagaaa ttgtcttatg taaacttgat tccttataac
    29101 ccagttagtg agcatgacca atatagccgt agtcccaaag agcgcgtgtt ggctttctat
    29161 gatacgctta agaaaaaagg ggtcaactgt gtggttcgtc aagagtatgg tacagatatt
    29221 gacgcagctt gtggacaatt gcgctctaac acaatgaaac gtgaccgcca gaaggcagtc
    29281 gcagaggtaa atccgtaaaa tgactaaaaa aagagaatta atcttaagat tgggagtggc
    29341 tgtttatagc ctatgcattg tctatttttg ctttactcct caagctaccg tggaagtggg
    29401 aactccaggt attcagcatc ttggacgcct ggtttttctt ttgactcctt tcaattctct
    29461 ctggaaactg ggcgaagtga gtgacattgg acaattatgt tggatttttt tacaaaatat
    29521 cctcaatgtc ttcttgtttt ttcctctgat tttccaactc ctttatctat ttccaaattt
    29581 gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg agtcttggaa tcgagtgtac
    29641 gcaattaatc ttggactttt tctttgattt caatcgcgtc tttgagattg atgatttgtg
    29701 gaccaacact ttgggtggct atctggcttg gctcctttat aaacgattac ataaaaacaa
    29761 gataaggaat taaaatgagt attttagaag ttaaaaatct gagtcacggt tttggtgacc
    29821 gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg agaacatatc ggcttggtcg
    29881 gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt gactggtaaa atgctgccag
    29941 atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg ttacttggat cagcactctg
    30001 tccttgctga aagacagtcg gtgcgtgatg ttctccgtac ggcttttgat gagcttttca
    30061 aagctgaagc tcgtatcaat gacctctata tgaaaatgac tgaagacggt gcggatgttg
    30121 atgctctcat ggaagaagta ggagaacttc aagaccgtct ggagagtcgt gatttctata
    30181 tcttggatgc taagattgac gaagtagcgc gtgctcttgg tattatggac tttggcatgg
    30241 atacggatgt aacttctttg tcaggtgggc aaagaaccaa ggtgcttttg gcaaaacttc
    30301 tccttgaaaa gcctgatatt ttgctgttgg acgagccgac caactacttg gatgctgagc
    30361 atattgattg gctcaagcgc tatctccaaa actatgagaa tgcctttgtt ctcatttcgc
    30421 acgatattcc attcctcaat gacgttatca atattgtcta tcatgtggaa aatcaacagc
    30481 tgacgcgtta ctctggtgac tactaccagt tccaagaagt ttatgctatg aaaaaatctc
    30541 agctagaggc agcctacgaa cgccagcaga aagagattgc agacctcaag gactttgtgg
    30601 ctcgtaataa agcccgtgtt gcaactcgta atatggctat gtctcgtcaa aagaaattgg
    30661 ataagatgga tattatcgaa ctccaaagtg agaaaccaaa accatccttt gatttcaaac
    30721 cagctcgtac accagggcgc tttatcttcc aagccaagaa cttgcaaatt ggttacgacc
    30781 gtcctcttac taagtcttta aatcttacct tcgaacgcaa tcaaaaggtt gcgattattg
    30841 gtgctaatgg tattggaaaa acaactctct tgaagagtct cttgggcatt atctcgccaa
    30901 tcgctgggga agtggagcgt ggagattatt tagaacttgg ttattttgag caggaagtag
    30961 aaggtggtaa tcgccaaact cctcttgaag ctgtctggaa tgcctttcct gcccttaatc
    31021 aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac aaccaaacat attgaaagcc
    31081 agattcaagt attatcaggg ggagagcaag ccaaggttcg tttctgtctc ttgatgaatc
    31141 gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca tttggatgtg gatgcaaagg
    31201 atgagctcaa acgcgctctc aaagaataca ggggatctat ccttatggtc tgccacgagc
    31261 cagactttta tgaaggttgg atagaccaaa tatgggattt taataattta acttaagaat
    31321 gagagtaaaa gaaatacagt accgaatgtg gatactgtat ttttttggtt tttaagattt
    31381 aaaatcgtag tctttcacca cttcgatgct gtcgattgtg atagcagtag ttggcttgtc
    31441 tttttcatct ttttcggctt tagcaatctt atccacaaca tccataccgt caatcacttg
    31501 accaaagact gggtgtttgc cgtctagact agggtttcca ccttctttgt aggcttcgat
    31561 aattttctgt ggatacttgc ttgtagggag tttagaagag gtatctgtag agttttggtt
    31621 gatgaagaac tggctgccat tggtgtttgg ttgaccagta ttagccatag caagagcacc
    31681 acggatgtta tacaaataag gagtaatctc gttcttgaaa ccagttcctt tgtctttagt
    31741 cttatccttg tcatgccaga tggactgacc acctgtaccg tccccttttg gatctccagt
    31801 ttggaccata aagccatcga tgacacggtg gaaggtaata ccgttatagt agccttcttt
    31861 ggcgtgagtg aggaaatttt caaccgctag aggagcgagt ttagggaaga gtttaatgcg
    31921 aatatcacct tggcttgtgt ggagaatcac ttcggcttca tcttcagcaa cttccttaga
    31981 tagttgtggg aaattggcgt tttcgtttgt taaagcatgg tttaactcct tggcagattg
    32041 ggcagctact ttggaacttt cttcagcagc aagactggaa tcaacataat catcaccacg
    32101 cagactgcgt tggacgctgc tacacccagc tagggctaca gtagacagta aaagaagggt
    32161 tgctagtttt ttcattctgt tcctctcaaa aattcattta taccattgta ccctaaaagg
    32221 aagtggattt caaatattag tagtttacag aactggctta gataatagtt gggatttcat
    32281 catcatcttg aaaatcttca acttcttccc cagtaaatgg tttctgaaaa gaacttagta
    32341 taaaacgggc aattggttca acaattagga aatttagagg aagagctgca ataaagttta
    32401 cgaaccaggc gcttagatag gtattgggtg tgatagcaat gccattgtaa aaaagtccat
    32461 agaaggacat gaaagtgacc agctaattct tcttctgaaa aatgctcatg aagggcttga
    32521 tccaggtcgc aagatttcat tttagaaagt ccagtaattc ccttcttctt caggatattc
    32581 tttttcatgg tagtatttag atggtcaagt gagtcaaaag aagtttcgac aagagcatac
    32641 cctttttcta ccagagtttt tagatgttta gggggcatca ataccataag tgtactcaaa
    32701 gtattttgga aaccagatct taagaaagct cgtaaagcta gtcagttctc taaacgctaa
    32761 gaactagcta caacacagca tttacaacac ttcatggttc acaccatggg gtgtttttta
    32821 atgattttaa gcaaaattca cacttaattg aaagttattt aaattagatg aaaatttatt
    32881 ttttgaaaaa gtgggaaaac attgattcta agcgaatttt gaatcatatt cgaatgggag
    32941 tttttaaaat catgtttcag tggtaaaagt accaaactgg attctccata gtaaaatgat
    33001 atctcctgct agtgaatcat ctgctaataa gtccatattt cgcttgggaa cgggcttggg
    33061 acttaggagc caagtatcca aatctcgttc aggcgatatg aagggtttga cttggtgttc
    33121 tttataaaat ttttctaaaa tagtattcac ggatagcatc tttcaaacat ttatttccta
    33181 ttctaacaaa tttctaaata ctttaagaaa tttatagtct gtcaagtttt tttcttgaca
    33241 catgccagaa atctgctata atagaacatg tgctaaatag ctcagctatt tcaccgaaat
    33301 aaaaaattaa agaaatgaga ctttaaaaat ggcagttaaa atccgtttga ctcgtatggg
    33361 ttctaagaaa aaacctttct accgtatcaa cgtagcagat tcacgttcac cacgtgacgg
    33421 acgtttcatc gaaacagttg gaacttacaa cccacttgtt gctgaaaacc aagtaacttt
    33481 gaaagaagac cgcgttcttg catggttggc taatggagct caaccttcag acacagtacg
    33541 taacatcctt tcaaaagaag gcgtattgaa aaaattccac gattctaaat tctcaaaata
    33601 agtttaaagt aggttgacag atggatacga ttgaaaatct cattattgcg attgtgaaac
    33661 ccttaatttc acaaccagat gccttaacta tcaagattga agatacacca gaatttttgg
    33721 aatatcattt gaatcttgat caaagcgatg tgggtcgtgt aatcggtcgt aagggtcgca
    33781 ctatttctgc gataagaacg attgtctact ctgtcccaac tgaatacaaa aaagtaagaa
    33841 tcgttattga cgaaaaataa gaagggcggg acggatgtct cgcttttttg tgtggaatag
    33901 aagatatagt aaaatgaaat aataacagga caaatcgatc aggacagtca aatcgatttc
    33961 taacaatgtt ttagaagtaa aggtgtacta ttctagtttc aatatactat aaaagattga
    34021 acgtttaggc aattccaaga ctacttactc gaacattaac agcagtctcg gactgatgaa
    34081 ggtctcttta tgaagttagt ggaggaagtc ggagaagtag ccgaggtttt gaataggcgc
    34141 tctggtcgaa aagaagggat aggattcgaa cgaggaacct gccatagaac tggctgatat
    34201 cattcactac accgtcgcta ttgctgttat caagcatatt gacctaacta gaaccatctt
    34261 tgagaaagac aaaaccgcag ccgttaatta ccaacataaa catgatttgg aaggattctt
    34321 gaagggaaag tagagatgtt gtccccttcc tccaacttga gaaaatcttt ggaacgtgat
    34381 aaaataaagg ataaggattt ttaataattc attatataga atgagtggat ttctttatga
    34441 agaggtttga agtatctaca gaaattggta gcctctctgt tacttatcaa aaacaaaaga
    34501 aagtgctagt ttgtctaaac ggagcaggtt tgctaccaag ttatgaaaat ttttcactta
    34561 tacttgaaaa acctcctcct acaattggtt atttgacaat tgattttccg aacacaggta
    34621 ggagtccgat tcatgaccaa gctggaaaaa atctagataa tcttgcagat gcggtttatg
    34681 aagtacttga agaattagga atttctgaat atatactttg tgcacatagt tggagtggaa
    34741 ttttagcttg caaattactc gagaaaccaa ttaagcgtca gactttagta gcaattgaac
    34801 cgacaactaa aaaagtcatg tttgctgatt tttcagaaaa tccttatcca gaaatggaag
    34861 agcagatgag gctgattgac gagtgtggtc ctgaacttta ttttaagaac ttaactcaag
    34921 caacatttag tcctgaaacg aataaaaaaa tctgggaatt aatgcaagaa aaaggcttag
    34981 agttggaaaa tcaagatcca gaatttcaga tatctggaga gattactgag gaagattttg
    35041 agaatttgtc gatagaatct catgtccctg tatttatttt ttgtcagact tatagagaaa
    35101 aagagtacag agaatcagaa tattggactt ccaatactaa actcatttta ggagggaatc
    35161 accattattt acaatggtca gaatcggaaa aaattgcggc tattattcga gaattgtcag
    35221 aataagatgg aaaaaaggag attacaggag acaagatgaa ctactttaat gttgggaaaa
    35281 tcgttaatac gcagggatta cagggtgaga tgcgagtctt gtctgtgacg gattttgcag
    35341 aagaacggtt taaaaaagga gctgagctgg ctttgtttga tgaaaaagat cagtttgtcc
    35401 aaacagtgac catcgctagc caccgtaaac agaagaactt tgacattatt aaattcaaag
    35461 atatgtacca tatcaatact atcgaaaagt acaagggata cagtctcaag gtcgctgagg
    35521 aagatttgaa tgacctagac gatggtgaat tttactatca cgagattatc ggtttggaag
    35581 tctatgaggg tgatagcttg gttggaacca tcaaggaaat cctgcaacca ggtgctaatg
    35641 atgtctgggt ggtcaaacga aaaggcaaac gtgatttgct tttaccttat atcccaccag
    35701 tggttctcaa tgttgatatt ccaaataaac gggtcgatgt ggaaatctta gaagggttag
    35761 acgatgaaga ttgatatttt aaccctcttt ccagagatgt tttctccact ggagcactca
    35821 atcgttggaa aggctcgaga aaaagggctc ttggatatcc agtatcataa ttttcgagaa
    35881 aatgctgaaa aggcccgtca tgtagatgat gagccctacg gaggcggtca gggcatgttg
    35941 ctcagagcac aacctatttt cgattccttt gatgctattg aaaagaaaaa tccgcgcgtt
    36001 attctcctcg atcctgctgg aaagcagttt gatcaggctt atgctgaaga tttggctcaa
    36061 gaggaagagc taatctttat ctgtgggcac tatgagggtt atgatgagcg cattaagacc
    36121 ttggtaacag atgagatttc cctaggcgac tatgtcctca ctggtggaga attggcagct
    36181 atgaccatga ttgatgctac agttcgcctg attccagaag tgattggcaa ggagtctagc
    36241 caccaagatg atagtttttc ttcaggtctt ttagaatatc ctcagtacac acgtccctat
    36301 gattatcgag gcatggtcgt gccagatgta ttgatgagtg gccaccatga aaagattcgt
    36361 cagtggcgat tgtacgagag tttaaagaaa acctacgagc gcagaccaga tttacttgaa
    36421 cattatcaac tgacagtaga agaagaaaaa atgctggcag aaatcaaaga aaacaaagaa
    36481 taaaggagaa acctatgcaa gtaatcaaac gtaatggcga aattgctgaa tttaatccag
    36541 ataagattta ccaagccatc ttgaaggcag cccaaactgt ttatgttttg acagatgatt
    36601 tgcgtcaaaa tcttgctcaa gtcactaaga aggtagtttt ggatttacaa gaagccaagg
    36661 tggaacgtgc gactatcagt atgattcaat ctatggttga acatcgttta ttgggcgcag
    36721 gttacattac cattgcagaa cactatattt cctatcgttt acaacgtgac ttggaaagaa
    36781 gtggttatgg agatcatatc gcagttcatt tacattttga acaaattcgc taagaaaaag
    36841 agtgggatga agcaactaca tctcactctt tcttaaatct atttttttgg gctgtttgga
    36901 cagttgaggg gacaaatcgc aggcgttgaa tatcgcttat acggataatc cggctcacat
    36961 ttttggaaaa atttttcacg ataatttgct ggccttgctg atcatatttg atgatatcac
    37021 ctgtaaagct tgtctcagac aagataaggt gaacagcggt ttgtttctgg atagcctctt
    37081 caatagtggc tgtaagggag ttggtttcag tctggtcagg ttggtcatgt ccatttaaaa
    37141 aatcatgtat tttatctaga acttgctgga atttatgtct catattggcc tcccttcttt
    37201 tatatcaata ttatataaaa ttttcctaaa atctacaaga ttttacgaat aaactaatga
    37261 aactaaaaaa ggagaagaaa atggcagaat ttacatttga aatcgaagag cacttgttga
    37321 ctctttctga aaacgaaaaa ggttggacca aggaaattaa ccgtgtgagc tttaatggtg
    37381 cccctgcaaa gtttgatatt cgtgcttgga gtccagacca tactaaaatg ggcaaaggga
    37441 ttactctctc aaatgaagaa tttcaaacga tggtggatgc ctttaaaggc aactaatact
    37501 cttcgaaaat ctcttcaaac cgcatcagct ttgccttgcc gtatgtatgg ttactgactt
    37561 cgtcagtttc atctacaacc tcaaaacagt gttttgagca gcctgcggct agcttcctag
    37621 tttgctcttt gattttcatt gagtataagt tttcaaaata aaaaaaagga tattgagtca
    37681 tgataactcg gtatcctttt ttagttagta aagtaagtct gatttttaag gcgttgaagt
    37741 aggggacggc taataaaact aatagccaga agtttgccaa ggtctggaat gataaaggga
    37801 agaaccccca caacaagagc tttttcaaat gccattccag ctaggaaatg caagctgaga
    37861 atcccgccga caaagacaag ggcatcaccc aagaggtttg caagaaaaat cttaacaaca
    37921 ccactcttgc tgttggttag agaggaagta agtccagagt aaacgagata aaaccaaaga
    37981 tagcctgcag tagggccaac taaagcctga aaaccagctc cacctcctgc aaagacagga
    38041 agaccgatag cacctagaag aagatagagt ccagcagaaa gtacagcctc tctcggtcta
    38101 aagacagtag caatcaagcc gattgcaaag ttttgcagag tgaagggaac aggtccaatt
    38161 ggaagactga tttgtgccaa aacagcaatg agagcagccc caatagcagg gatagcataa
    38221 acgtgagctt ttttcaaaat agttaacctc ttttctaatg tatagtaact attatactca
    38281 tataggagtc gatgtcaacc attttttaaa aacaaggtaa caaaaactgt aacagccgat
    38341 tttcgtgact agtcaagttg gataattttt tgttgattcg aaaatcatta aaaaagaagc
    38401 agacatattt atatcagctt cttttgtttc gattaacgca tggttacaaa ttcttcagat
    38461 gaagttgggt gaatcgctac agttgcgtca aagtcagcct tggttgctcc cattttgata
    38521 gcaacggcaa atccctgaat catttcatca acgccgtagc caattccatg aagtccgaca
    38581 actttttctt ctgaaccagc tgttatgagt ttgaaacggg attcttgacg gttgcgagtg
    38641 caagcagagt acatagatgc aaagcttgat ttgtaaacct tgatttggtc ttgaccgtat
    38701 tctttaatag cttgctcttc tgtcaaacca acagttccga tagcagggtg tgaaaagaca
    38761 acagttggaa tagttgagta atccattttt gcagtagttt ttccgttaaa gagacgttca
    38821 gatagggtac gtccggcctt gattgcaact ggagtcagtt ctttctcgcc cgttacatca
    38881 cctagagcat agattccctc aacaacagta ttttggtatt catccacttg gataaagcca
    38941 cgttcgttca gagtcactcc agctttttca agttgcaagc ccttaacgtt tggacggcgg
    39001 cctgtagccc agataacttg gctagctgtg tgactagtac catcttcgaa atgaatggta
    39061 atgccgtcag tagttttttc taacttgaca gggactttgt gagtgtgaag tggtaagttt
    39121 gttctttcca tttccttgac caaaccttca acgatgtagg aatcaaaacc acgtaaagga
    39181 cgatcgcggc gaacaaagag atctgtcttg acaccaaaag tgtggagtac gccagctaat
    39241 tcaacggcga tataaccagc gcctagaatg gcaactgact ctggaagttc ttcccaggca
    39301 aatacatcat cagaagagcc acctagctca gcaccaggaa tattaggaat acttggatgg
    39361 gcacctgtag caatcacgat atgtttagca cgaatcagtt caccatttac gcttacagta
    39421 tgagaatcta caaattcagc atgaccttca atcaagtcta caccgttgcg tttaaaacta
    39481 ccatcataag aagaacgagc gcgatcaatg taggcttcac gattgcgacg tagggttgca
    39541 aagttaaagt taagatcagt agtcttaaag ccgtagtctt ctccaaattg atggaaagtc
    39601 tcagcgattt gcgccccgta ccacatgatt tttttaggaa cacaaccgac gttgacacag
    39661 gttccaccta atttcttttc ctcaataacg gctgctttgg ctccatgttc accagcacgg
    39721 ttcatggtag cgattcctcc gctacctcca ccgatagcaa tgatatcata ttctctcatt
    39781 gaaaactcct ttgtaatctt ttaaatagta gagtgtcttt tttgatagtt atattttatt
    39841 ctttttttga tttgattgca aaaatctgct acgcacaaaa aattgcaaaa aagcttgcca
    39901 aataagtcaa gatagtgtat tatatatcta gtacaataga aaagcaaaat tccgaacgat
    39961 tgtttaatcc tgaactgcca ttatttccat ctgaactgca ttgtttgctg gagggaaatt
    40021 tggtataata gcaaagtatt gtaaaaaaga aaaggagttt cattatgaag aaaaagaatg
    40081 gtaaagctaa aaagtggcaa ctgtatgcag caatcggtgc tgcgagtgta gttgtattgg
    40141 gtgccggggg gattttactc tttagacaac cttctcagac tgctctaaaa gatgagccta
    40201 ctcatcttgt tgttgccaat gaaggaagcg tggcatcctc tgttttattg tcagggacag
    40261 taacagcaaa aaatgaacaa tatgtttatt ttgatgctag taagggtgat ttagatgaaa
    40321 tccttgtttc tgtgggcgat aaggtcagcg aagggcaggc tttagtcaag tacagtagtt
    40381 cagaagcgca ggcggcctat gattcagcta gtcgagcagt agctaaggca gatcgtcata
    40441 tcaatgaact caatcaagca cgaaatgaag ccgcttcagc tcaggctcca cagttaccag
    40501 cgccagtagg aggagaagat gcaacggtgc aaagcccaac tccagtggct ggaaattctg
    40561 ttgcttctat tgatgctcaa ttgggtgatg cccgtgatgc gcgtgcagat gctgcagcgc
    40621 aattaagcaa ggctcaaagt caattggatg caacaactgt tctcagtacc ctagagggaa
    40681 ctgtagtcga agtcaatagc aatgtttcta aatctccaac aggggcgagt caagttatgg
    40741 ttcatattgt cagcaatgaa aatttacaag tcaagggaga attgtctgag tacaatctag
    40801 ccaacctttc tgtaggtcaa gaagtaagct ttacttctaa agtgtatcct gataaaaaat
    40861 ggactgggaa attaagctat atttctgact atcctaaaaa caatggtgaa gcagctagtc
    40921 cagcagccgg gaataataca ggttctaaat acccttatac tattgatgtg acaggcgagg
    40981 ttggtgattt gaaacaaggt ttttctgtca acattgaggt taaaagcaaa actaaggcta
    41041 ttcttgttcc tgttagcagt ctagtaatgg atgatagtaa aaattatgtc tggattgtgg
    41101 atgaacaaca aaaggctaaa aaagttgagg tttcattggg aaatgctgac gcagaaaatc
    41161 aagaaatcac ttctggttta acgaacggtg ctaaggtcat cagtaatcca acatcttcct
    41221 tggaagaagg aaaagaggtg aaggctgatg aagcaactaa ttagtctaaa aaatatcttc
    41281 agaagttacc gtaatggtga ccaagaactg caggttctca aaaatatcaa tctagaagtg
    41341 aatgagggtg aatttgtagc catcatggga ccatctgggt ctggtaagtc cactctgatg
    41401 aatacgattg gcatgttgga tacaccaacc agtggagaat attatcttga aggtcaagaa
    41461 gtggctgggc ttggtgaaaa acaactagct aaggtccgta accaacaaat cggttttgtc
    41521 tttcagcagt tctttcttct atcgaagctc aatgctctgc aaaatgtaga attgcccttg
    41581 atttacgcag gagtttcgtc ttcaaaacgt cgcaagttgg ctgaggaata tttagacaag
    41641 gttgaattga cagaacgtag tcaccattta ccttcagaat tatctggtgg tcaaaagcaa
    41701 cgtgtagcca ttgcgcgtgc cttggtaaac aatccttcta ttatcctagc ggatgaaccg
    41761 acaggagcct tggataccaa aacaggtaac caaattatgc aattattggt tgatttgaat
    41821 aaagaaggaa aaaccattat catggtaacg catgagcctg agattgctgc ctatgccaaa
    41881 cgtcagattg tcattcggga tggggtcatt tcgtctgaca gtgctcagtt aggaaaggag
    41941 gaaaactaag atgcagaatc tgaaatttgc cttttcatct atcatggctc acaagatgcg
    42001 ttctttgctt actatgattg ggattattat cggtgtttca tcagttgttg tgattatggc
    42061 tttgggtgat tccctatctc gtcaagtcaa taaagatatg actaaatctc agaaaaatat
    42121 tagcgtcttt ttctctccta aaaaaagtaa agatgggtct tttactcaga aacaatcagc
    42181 ttttacggtt tctggaaagg aagaggaagt tcctgttgaa ccgccaaaac cgcaagaatc
    42241 ctgggtccaa gaggcagcta aactgaaggg agtggatagt tactatgtaa ccaattcaac
    42301 gaatgccatc ttgacctatc aagataaaaa ggttgagaat gctaatttga caggtggaaa
    42361 cagaacttac atggacgctg ttaagaatga aattattgca ggtcgtagtc tgagagagca
    42421 agatttcaaa gagtttgcaa gtgtcatttt gctagatgag gaattgtcca ttagtttatt
    42481 tgaatctcct caagaggcta ttaacaaggt tgtagaagtc aatggattta gttaccgggt
    42541 cattggggtt tatactagtc cggaggctaa aagatcaaaa atatatgggt ttggtggctt
    42601 gcctattact accaatatct cccttgctgc gaattttaat gtagatgaaa tagctaatat
    42661 tgtctttcga gtgaatgata ccagtttaac cccaactctg ggtccagaac tggcacgaaa
    42721 aatgacagag cttgcaggct tacaacaggg agaataccag gtggcagatg agtccgttgt
    42781 atttgcagaa attcaacaat cgtttagttt tatgacgacg attattagtt ccatcgcagg
    42841 gatttctctc tttgttggag gaactggtgt catgaacatc atgctggttt cggtgacaga
    42901 gcgcactcgt gagattggtc ttcgtaaggc tttgggtgca acacgtgcca atattttaat
    42961 tcagtttttg attgaatcca tgattttgac cttgttaggt ggcttaattg gcttgacaat
    43021 tgcaagtggt ttaactgcct tagcaggttt gttactgcaa ggtttaatag aaggtataga
    43081 agttggagta tcaatcccag ttgccctatt tagtcttgca gtttcggcta gtgttggtat
    43141 gatttttgga gtcttgccag ccaacaaggc atcgaaactt gatccaattg aagcccttcg
    43201 ttatgaatga gatcaacaag atggacactc gtctatcttg tttttgtatg gatttcccta
    43261 tcgaaattca ttaaaaatgt gatataatga agtgttagaa aaacaggttt catttgcctg
    43321 gaaaggaaaa attatgtctg aaaaaaattt ttatattaca acgccgattt actatccatc
    43381 tgggaaactt catatcggtt ctgcctacac aactatcgca tgtgatgtcc tagcacgtta
    43441 caaacgcctg atgggctacg atgtatttta tctgacaggt cttgatgaac atggtcagaa
    43501 aatccagcag aaagcggaag aagctggtat tacacctcaa gcctatgttg atggaatggc
    43561 ggttggagtt aaagaactct ggcaattact agatatctca tacgataaat ttatccgtac
    43621 aactgatgac taccatgaaa aagttgtcgc acaggtcttt gaacgcttac ttgctcaaga
    43681 tgatatttac ttgggtgaat actctggttg gtattcagta tcagacgaag aattctttac
    43741 agaaagccag ctggcagaag ttttccgtga tgaagctgga aatgtgactg gtggtattgc
    43801 tccatcaggt catgaggttg aatgggtttc tgaagaatca tactttcttc gccttagcaa
    43861 ataccaagac cgtttggtcg aatttttcaa agctcatcct gaatttatca cgccagatgg
    43921 tcgccttaat gaaatgctac gcaacttcat cgagccaggt ttggaagatt tggcggtatc
    43981 tcgtacaacc tttacatggg gagtgcctgt cccatcaaat ccaaaacacg ttgtctacgt
    44041 ttggattgat gcccttctta actatgcgac agctcttggc tacgctcaag acgaacatgg
    44101 taactttgac aagttctgga atggaacagt cttccatatg gtaggaaaag atatccttcg
    44161 cttccactct atctactggc caatccttct tatgatgttg gatgttaaat tacctgatcg
    44221 tttgattgcc catggttggt ttgtcatgaa agacggaaaa atgtctaagt caaaagggaa
    44281 tgtcgtttac cctgaaatgt tggtagagcg ttatggacta gatccacttc gttactacct
    44341 catgcgtaac cttccagttg gttcagacgg aacctttact cctgaagact atgttggccg
    44401 tatcaactat gaattggcta atgaccttgg gaacctcctt aaccgtacgg tttccatgat
    44461 taataagtac tttgatggac aaatccctgc ctatgtagaa ggtgtgactg aatttgatca
    44521 tgttcttgct gaggttgcag aacaatcaat cgcagacttc catacacaca tggaagcagt
    44581 tgactatcca cgtgcgcttg aagcagtctg gactctgatc tctcgtacca ataaatacat
    44641 cgatgagacc gcaccatggg tcttggccaa ggatgaagct cttcgtgacc aattggcaag
    44701 tgtcatgagc cacttggcag ccagcattcg tgtagttgct cacttgattg aaccatttat
    44761 gatggaaact agtcgtgcag ttttgactca acttggtttg gaagaagttt ctagtcttga
    44821 aaacttgagt ttggctgact tcccagcaga tgtgactgta gttgccaaag gaacacctat
    44881 ctttccacgt ctaaatatgg aagaagaaat cgcctatatc aaggaacaaa tggaaggcaa
    44941 taaaccagca gtcgaaaaag aatggaatcc ggacgaagtt gagctcaaac taaacaagga
    45001 tgaaatcaag tttgaagact ttgacaaggt tgaaatccgt gtggcagaag tcaaagaagt
    45061 gtctaaagta gaaggttcag ataagttgct tcaattctgc ttggatgctg gtgatggaga
    45121 agatcgtcag attctttcag gaattgccaa atactatcca aatgaacaag aattggtcgg
    45181 caagaaagtt caaatcgttg ctaacctcaa accacgtaaa atgatgaaaa aatatgtcag
    45241 ccagggtatg attctctcag ctgaacatga tggcaaatta acccttctca cagttgatcc
    45301 agctgtacca aatggaagtg tgattgggta aaagtagaca ggactagttc aggctagttc
    45361 tgttttttta tttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggtt
    45421 gctcaa
//
LOCUS       DBERDS010000013        42082 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.013, whole genome shotgun sequence.
ACCESSION   DBERDS010000013 DBERDS010000000
VERSION     DBERDS010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.013"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..835
                     /locus_tag="ACL73E_000814"
                     /pseudo
     CDS             1..835
                     /locus_tag="ACL73E_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(963..1211)
                     /locus_tag="ACL73E_000815"
     CDS             complement(963..1211)
                     /locus_tag="ACL73E_000815"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0800814.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(1159..2241)
                     /locus_tag="ACL73E_000816"
     CDS             complement(1159..2241)
                     /locus_tag="ACL73E_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGS0800815.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2367..3149)
                     /gene="gatD"
                     /locus_tag="ACL73E_000817"
     CDS             complement(2367..3149)
                     /gene="gatD"
                     /locus_tag="ACL73E_000817"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGS0800816.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3149..4492)
                     /gene="murT"
                     /locus_tag="ACL73E_000818"
     CDS             complement(3149..4492)
                     /gene="murT"
                     /locus_tag="ACL73E_000818"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGS0800817.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGTTQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4591..5907)
                     /locus_tag="ACL73E_000819"
     CDS             complement(4591..5907)
                     /locus_tag="ACL73E_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGS0800818.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6101..7327
                     /locus_tag="ACL73E_000820"
     CDS             6101..7327
                     /locus_tag="ACL73E_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGS0800819.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7526..9100
                     /locus_tag="ACL73E_000821"
     CDS             7526..9100
                     /locus_tag="ACL73E_000821"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0800820.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9364..10152
                     /gene="codY"
                     /locus_tag="ACL73E_000822"
     CDS             9364..10152
                     /gene="codY"
                     /locus_tag="ACL73E_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGS0800821.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10152..10727
                     /locus_tag="ACL73E_000823"
     CDS             10152..10727
                     /locus_tag="ACL73E_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGS0800822.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10809..10894
                     /locus_tag="ACL73E_000824"
     tRNA            10809..10894
                     /locus_tag="ACL73E_000824"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10843..10845,aa:Leu,seq:aag)
     gene            11167..12297
                     /locus_tag="ACL73E_000825"
     CDS             11167..12297
                     /locus_tag="ACL73E_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0800823.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12798..13556
                     /locus_tag="ACL73E_000826"
     CDS             12798..13556
                     /locus_tag="ACL73E_000826"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0800824.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMRLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13643..14155
                     /locus_tag="ACL73E_000827"
     CDS             13643..14155
                     /locus_tag="ACL73E_000827"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGS0800825.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14337..15281
                     /gene="metA"
                     /locus_tag="ACL73E_000828"
     CDS             14337..15281
                     /gene="metA"
                     /locus_tag="ACL73E_000828"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGS0800826.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            15290..15967
                     /locus_tag="ACL73E_000829"
     CDS             15290..15967
                     /locus_tag="ACL73E_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGS0800827.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            16065..16823
                     /gene="tpiA"
                     /locus_tag="ACL73E_000830"
     CDS             16065..16823
                     /gene="tpiA"
                     /locus_tag="ACL73E_000830"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGS0800828.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVVSKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16861..18366
                     /gene="lytC"
                     /locus_tag="ACL73E_000831"
     CDS             16861..18366
                     /gene="lytC"
                     /locus_tag="ACL73E_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGS0800829.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGTRYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18862..19380
                     /locus_tag="ACL73E_000832"
     CDS             18862..19380
                     /locus_tag="ACL73E_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGS0800830.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19510..20016
                     /locus_tag="ACL73E_000833"
     CDS             19510..20016
                     /locus_tag="ACL73E_000833"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGS0800831.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            20016..20186
                     /locus_tag="ACL73E_000834"
     CDS             20016..20186
                     /locus_tag="ACL73E_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800832.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            20218..21450
                     /gene="clpX"
                     /locus_tag="ACL73E_000835"
     CDS             20218..21450
                     /gene="clpX"
                     /locus_tag="ACL73E_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGS0800833.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21459..22046
                     /gene="yihA"
                     /locus_tag="ACL73E_000836"
     CDS             21459..22046
                     /gene="yihA"
                     /locus_tag="ACL73E_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGS0800834.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            22057..22437
                     /locus_tag="ACL73E_000837"
     CDS             22057..22437
                     /locus_tag="ACL73E_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGS0800835.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22489..23379
                     /gene="rapZ"
                     /locus_tag="ACL73E_000838"
     CDS             22489..23379
                     /gene="rapZ"
                     /locus_tag="ACL73E_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGS0800836.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23376..24353
                     /locus_tag="ACL73E_000839"
     CDS             23376..24353
                     /locus_tag="ACL73E_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGS0800837.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQAILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24350..25261
                     /gene="whiA"
                     /locus_tag="ACL73E_000840"
     CDS             24350..25261
                     /gene="whiA"
                     /locus_tag="ACL73E_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGS0800838.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25295..26260)
                     /locus_tag="ACL73E_000841"
     CDS             complement(25295..26260)
                     /locus_tag="ACL73E_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS0800839.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            26396..27253
                     /gene="cdaA"
                     /locus_tag="ACL73E_000842"
     CDS             26396..27253
                     /gene="cdaA"
                     /locus_tag="ACL73E_000842"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGS0800840.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            27240..28019
                     /locus_tag="ACL73E_000843"
     CDS             27240..28019
                     /locus_tag="ACL73E_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGS0800841.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            28043..29395
                     /gene="glmM"
                     /locus_tag="ACL73E_000844"
     CDS             28043..29395
                     /gene="glmM"
                     /locus_tag="ACL73E_000844"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGS0800842.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KTIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTIEEVDYYVDTITDVVRAEIGID
                     "
     gene            29469..29843
                     /locus_tag="ACL73E_000845"
     CDS             29469..29843
                     /locus_tag="ACL73E_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGS0800843.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29845..30693
                     /locus_tag="ACL73E_000846"
     CDS             29845..30693
                     /locus_tag="ACL73E_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0800844.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30959..31726
                     /gene="dapB"
                     /locus_tag="ACL73E_000847"
     CDS             30959..31726
                     /gene="dapB"
                     /locus_tag="ACL73E_000847"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGS0800845.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLPDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31723..32922
                     /locus_tag="ACL73E_000848"
     CDS             31723..32922
                     /locus_tag="ACL73E_000848"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGS0800846.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAI
                     TEKYQSLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            32919..34790
                     /locus_tag="ACL73E_000849"
     CDS             32919..34790
                     /locus_tag="ACL73E_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0800847.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMSRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34933..36117)
                     /gene="mntE"
                     /locus_tag="ACL73E_000850"
     CDS             complement(34933..36117)
                     /gene="mntE"
                     /locus_tag="ACL73E_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGS0800848.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36421..39117
                     /locus_tag="ACL73E_000851"
     CDS             36421..39117
                     /locus_tag="ACL73E_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS0800849.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVILANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            39130..39921
                     /gene="yghU"
                     /locus_tag="ACL73E_000852"
     CDS             39130..39921
                     /gene="yghU"
                     /locus_tag="ACL73E_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGS0800850.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            40037..40447
                     /locus_tag="ACL73E_000853"
     CDS             40037..40447
                     /locus_tag="ACL73E_000853"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS0800851.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40459..42054
                     /locus_tag="ACL73E_000854"
     CDS             40459..42054
                     /locus_tag="ACL73E_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800852.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRVYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
BASE COUNT        12387 a         7870 c         9589 g        12236 t
ORIGIN      
        1 ttcaagaatt aatgactgag ttttcgttag atcttcttct aaaagccatt aaactagctc
       61 gttcgaccta ctactatcac ttgaaacagc tagacaaacc agataaggac caagagctta
      121 aagctgaaat tcaatccatt tttatcgaac acaagggaaa ttatgcttat cgccgggttc
      181 atttagaact aagaaatcgt ggttatctgg taaatcataa aagagttcaa ggcttgatga
      241 aagtactcaa tttacaaact aaaatgcgac agaaacgaaa atattcttct cataaaggag
      301 acgttggtaa gaaggcagag aatctcattc aaggccaatt tgaaggctct aaaacaatgg
      361 aaaagtgcta cacagatatg acagaatttg ccattccagc aagtactcaa aagctttact
      421 tatcaccagt tttagatggc tttaacagcg aaattatcgc ctataatctt tcaacttcac
      481 ccaacttaga acaagtacaa acaatgttgg aacaggcatt cacagagaag tactacgaga
      541 atacgattct ccatagtgac caaggctggc aatatcaaca cgattcttat catcggttct
      601 tagagagtaa gggaattcaa gcatccatgt cacgcaaggg aaacagccaa gacaacggta
      661 tgatggagtc cttctttggg attctgaaat ttatggctat gagaaaacat ttaaatcact
      721 taatcaattg gaacaagcta ttgtagacta tattgattac tacaacaata aacgaattaa
      781 ggtaaaacta aaaggactta gtcctgtgca gtacagaact aaatcctttg gataaattaa
      841 ttgtctaact tttggggggc agtacatttt aacacttgat aatatgcgtt ttattgtggg
      901 aagattttcc tcattttcta gtgaaattga actttttcta acatcttttg atagatgact
      961 tcttaatcaa ttatcatttc cattgttgtt tcttggggtt tcatcccttg tctttgataa
     1021 aagcggagag caccctcgtt atcattccag acacttaggg ttagattatt gcagccaatt
     1081 tctttagcat aatagcagaa aaatgacaat aaaatagccc ctagatattt tgaaaggaaa
     1141 gcataggggc tatatagttt aatcaaaata aagcaaatct ttgctggtgc ttgtaaagag
     1201 gtcgaagcca tccttggtaa caacaccgca gtcttcaata cgaacaccga ctttaccagg
     1261 gatatagata cctggttcaa cagagaagca catgccttct tcgatgacca tgtcgtttcc
     1321 ttccatgata gatgggaatt catggacatc cataccgata ccatgcccga gacggtggtt
     1381 gaagtactca ccataaccag ctttttcgat gatctcacgg gcagcgcggt ccacttcatg
     1441 agcagtcaca cctggcttga taaagtcaag agcagcttgt tgggcttcaa gagtcaagtt
     1501 gtaaatatct ttcttgaatt ggtctggttt gccgacagcg actgtacgag tcatatctga
     1561 cgcatagcca ttgaccagaa cccccaggtc aaagaggaga agagcatcat tttcaacctt
     1621 attagctgct ggaatgccgt gtggattcgc agcattatca ccagtcaaga ccatggtatc
     1681 aaagctcatt tcgtaacctt cacgtttcat ggcaaagtca atttgtgcga tgatatctgt
     1741 ctcagtctta tcaagagaaa tattgtcaaa accaacatga acagccttgt cagcataaag
     1801 acctgcaacc atcatttttt gtacttcatc agctgatttg atgaggcgca tgcgttggat
     1861 acgaggagtg aggttttcaa actcagcagt ttcaaaaatt gttttcaaac catggtattt
     1921 ggtcaagatg agattgtcaa actcaacagc gacacgtttg aagtcaagtt gtggaagagc
     1981 atgtttgatt ttttgccatg gattttcaga atcgacatag cccactactg ggaaggaaac
     2041 ggtgctactt gcacgttcta cttcaagagc tgggacaaag aggagaggtt cctgatccgc
     2101 taggacaaag aggaacattt ggcgttcatg gggatcactg taaaaaccag tgaggtaatt
     2161 gattgtgacg gggtcagata cgacagcgac gtctagtttt tctgattcaa gatatgttag
     2221 gatttgttgt aatttagaca tatgctacct tctttctacc cctctatttt ggcaaaaaat
     2281 gagagaaaat gcaagggaga agggtaaaag aaaagacaaa aaactccgac aagataacgg
     2341 agttctttga tatcattttc ctttgtttaa gaaaagtcag ccttgctttt gacgtcactg
     2401 tactcttcag cgatttcttg gctgaggata tcctcatagg cagggagttg gatatcctga
     2461 ccatatttct tcttgagggc agtagtaact aggcgataag ccagattggc attacgagag
     2521 aggataggcc cgtggaagta ggaaccaaag acattcttat aatgaacccc ttcaccgacc
     2581 ttttcttcgt tgtttccatt tccatagaca acttgtccca gcggtttttg gtcatcagag
     2641 aggaaggtac ggccttggtg attttcaaat ccatagtagg tttcatcgaa atcttcattg
     2701 tgaatcttga tgtcaccgat aaaacggtta ttggtctggt tgagcgtgta gtgtcccatg
     2761 acccctagcc cttcgatacg ttttcctgaa gcttcaacat aatattgacc caatagttgg
     2821 aaaccaccgc agatagccag aactacaccg tcgttttgga tgtagttgtc aatgctctct
     2881 tttttagcag gtaggtcgtc tgcaatgata ctttgttcaa agtcttgacc accaccgaaa
     2941 aaggcgatgt cgtagtgatt ttcatcaaag tcatcatgga gagaaacgat gtcaacggtc
     3001 acatgggctc ccagtttttc agccacatac ttgagcatga ggatgtttcc attgtccccg
     3061 taggtattca tgagatttcc gtagaggtgg gcaatgttga gctgataggg gtaattgcca
     3121 tcttttgagg aaagtgaagt ataaaccatt agttcatctc ctttctaaca atctgacgac
     3181 tagccagcag ttcacgaaat tccagcatgg cagtataagt tgccagaata taggcatgct
     3241 tgcagtcttg attctcaatg gtcttgagaa cttgctccag attactcgtt tcagtgattt
     3301 tctcagctgg atagccagtc actcggaggc gacgagcgat ttcagaatga cgaacaccgc
     3361 cagcgttgat ttcaggaatg tccatgtcag tgatttgctc aaagtctgca tcccagatcc
     3421 agctagtgtc aattccatct gcatagttgg cattaaggag gacagatagg ctaaatggat
     3481 aaggtgctag tttgatcatt tcgatagctt gggttgtacc gactggattt ttaatcaaga
     3541 caagggtaca ttccttgtca ccgatatgaa aggtttcttg gcgtccaaag acagcacggc
     3601 tcttgtcaaa tccctgtttg atgagttgcg aatcggcacc taggaaacgg gcgatggcca
     3661 cagcagctag ggcgttatat atattataga gcccgccgat ttggataccg tattcttggc
     3721 cgtctatgac aaagcgagag cgattgttgg tcaactcaac caattttgtc aaacgatagt
     3781 cgagatcagg acgtttacat ccacaacctt cacagatata ggcacccaag tttgcatagg
     3841 tattatgctc atatttgagg atgccttggc agtcaggaca gagaatccct tcggtattgt
     3901 agtgagccag ttgggctggt cctttttcca agtcaaaacc aaaatactct atagggtttg
     3961 gaatagttgg cttgtagaaa agtggactgt ctccgttaag gagaacagta gcagttggaa
     4021 ctttccgaat ggcatccaat atcatgttat aggtagtata gatttcaccg aaacggtcca
     4081 tctggtcacg gaagatatta gtaatgacaa aaagactagg ctggatatag tcacagatac
     4141 gagatagact ggcttcgtca atttcgagga cggcaatatt ttttccagtt ttagaagatt
     4201 tggctgttag gaaggttgtt gcaatccctg taatcatgtt ggcaccgctt gggttggtta
     4261 gaacttgacc ataaacctct tttaaaatgc cgacagtgag ggcagttgtc agggtttttc
     4321 catttgttcc agtgacaacg acaatctcgt agttcttagc taggttttgt aaaatatctt
     4381 tatcaaattg aagggcgact ttacctggga gcgtacttcc acgtccaaga cggcttaaaa
     4441 cgaagtggga agaacgccca gcaagaaggc ccaaagtagt ttttaagttc atgtttctat
     4501 tatatcacaa aagagggaaa agacagattt ggtgtttcgt agaagtaaaa acagcccaaa
     4561 gagggctgtc agttaagatg agatttcaac ttaaatcgca aacaagtcat tcaagttctc
     4621 agccaaggtt gggtgagtga agatttgttt tgtgaagtaa gtgtaaggaa tcttgttgtc
     4681 catagcaaca gtaatgatgt tgatgatttc ttgagaacct tctgagaaga tgcttgcacc
     4741 aagaatttct tttgtttcag tattaacaac agctttgaaa gctccgcgaa ggtctccatt
     4801 tacgtgacca cgaggcatgg ctgcaacagg gatttctttc actgcgtatg gaagtttcaa
     4861 atcagctgct tggctttcag tcaaaccaac ttgtgaaagt gcaggtgtga tgaacatagt
     4921 atttggcaca ttgagacggt cctcaagtgt gtagctgcca tctccagcaa ggtagctgta
     4981 aacaacacgg aagtcatcaa gtgaaatgta agtaaattga agaccaccgt tgacatctcc
     5041 aactgcaaag acaccaggaa cgtttgtttg acagtgttta tctactttaa tagcgccacg
     5101 ttcagttagt tcaatatctg tattttcaag ttgaagtggt tctacatttg gtttgcgtcc
     5161 agttgcgtag agaagggcgt cgaaacggta agtttcgtct tcagttacga caagcacttg
     5221 gtcaccgtcg tttttaattt cagtagtatg gatattttga agcaattcaa taccgtcttc
     5281 ttccatgtat tgtttagcaa gagctgcgat ggaaggttct gcacgaggta ggaatgtatc
     5341 caaggcatct aggactgtaa ccttgcttcc tagtttattg taaaggccag caaattcaag
     5401 accgatattt ccgccaccaa ggactccaag tttttcaggc aatttatcca agctttggat
     5461 acctgttgag tcaaagacgt ttttgcttgt agcaagtcca gggattggca agacgtttga
     5521 aacagcacca gtgttgatga cgatagtttc agcagtcaat tcttgttttt catcaccagc
     5581 ttggatttcg atgactttat ttgaaaggaa gtgagcttca gcatcaaaga tattgacgcc
     5641 agtaccagca acagtcgtat agtttttacc gttgaggcga ccagtgatcg tgtttttggt
     5701 agcaatgact tcttcaaaag acaagtcttt ctcagcagca accagcaaag ttttagttgg
     5761 gatacaaccg atgttgatac aagttccacc gtacatagct ttgctacgtt caacgagggc
     5821 aacttttttg ccagctgaag ccaatttacc tgctagtgtt ttaccagctt taccaaatcc
     5881 gataacgatt aaatcataag ttaacattta gagttcctcc tattcgcatt tcattctagc
     5941 acaagaaaaa aacttttgca caattctgct acggaaaaga cagaaaaaga taaaaacgct
     6001 ttccagacaa aaaactagta attttttgac aagcttgata aactaaaatc ctatctattt
     6061 ttatataaga tagaaaaaat gttcgaaaat aggaggtttt atgaaatcga atcgttatat
     6121 tattgccttt gctggggtca ttttacactt aatgctgggt tcgacttatg cttggagtgt
     6181 ttatcgtaac cctattattg aaaaaacggg atgggatcag gcttctgttg cctttgcctt
     6241 tagtctagca atcttttgtt tgggcttatc ggctgcattt atggggcgtt tggtagaaaa
     6301 atttggtccg agagtcatgg ggagtctatc tgcttttcta tacgcaggtg gaaatatctt
     6361 aacaggattt gcaatagacc gtcaggaact gtggttgttg tatctagctt atggcatttt
     6421 aggtgggctt ggtttgggag caggctatat tacccctgtg tcaacgatta taaaatggtt
     6481 tcctgataaa cgtggtctcg caacaggttt agcgattatg gggtttggtt ttgcttcttt
     6541 attgactagt cccatagcgc aacatctcat cgcaggggta gggcttgtag aaacttttta
     6601 tattttaggt gcaagttact ttattatcat gctcctagct tcacaattca ttaagcgtcc
     6661 aaatgagcaa gagcttgcaa ttttatctgc ttcagggaaa gaaaaaacag actctctgac
     6721 gcaagggatg actgcaaatc aggctctaaa aagcaatcgg ttttatatgc tttggattat
     6781 tttctttatc aacatagctt gtggtttagg cttaatttca gcggcatcgc caatggcaca
     6841 ggagatggct ggcttgtcta caagtcatgc agcagtaatg gtgggtattt tggggatttt
     6901 caatggattt ggtcgcttgc tctgggcgag tttgtctgac tatatcggtc gccctctaac
     6961 ctttagtata ttactgcttg tcaatctttt cttttctctc tcactttggc tctttacaga
     7021 ttccgtttta tttgtagttg ctatgtctat tttgatgact tgctatggag ctggtttttc
     7081 tttgattcca gcttatctca gtgatatttt tggaaccaag gaattggccg ctctgcatgg
     7141 ttatatttta acagcttggg caatggctgg tttagcggga cctattttat tagcagagac
     7201 ttataaaatg gctcattcgt acacacaaac cttgttcgtt tttctcattt tatacagtat
     7261 cgccttggct ttgtcttatt atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct
     7321 tacatgattt tctgtagaaa tggggctatc ttttgctctg gtcttgtgtt atactagata
     7381 ggttgcaaag aaaacagtac ttttcttttg tggaaaagaa gcaacacgat tttatatcta
     7441 gttatatgaa aatacgtcat aaaaagaaaa gtataaacta agccctatag ggtggcttcg
     7501 caccaccttt agaaagaaga ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt
     7561 gctagcagaa attgaaaaag ctggttttgt agaagctagt cctatccaag aacaaactat
     7621 tcctttggcc cttgaaggca aggatgttat cggtcaagct cagactggta caggaaaaac
     7681 tgcagccttt ggcttgccta cccttgaaaa aatccgtaca gaagaagcga ctatccaagc
     7741 tttggtcatc gctccaactc gtgaactagc tgtccaaagt caagaagaac tcttccgctt
     7801 tggtcgtagt aagggagtca aagtccgttc agtatatggc ggatcaagca ttgaaaaaca
     7861 aattaaggct cttaaatctg gtgcccatat cgtggtggga actccaggtc gcctcttgga
     7921 cttgattaaa cgcaaggcct tgaaattaca agacattgaa acccttatcc ttgacgaagc
     7981 ggatgaaatg cttaacatgg gcttccttga agacatcgaa gccattattt cccgtgtacc
     8041 tgagaaccgt caaactttgc ttttctcagc aactatgcca gatgccatca aacgtatcgg
     8101 tgttcagttt atgaaagccc ctgaacatgt caagattgcg gctaaggaat tgacaacaga
     8161 attggttgac cagtactata tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg
     8221 tctcatggat gtggcacaac cagaactcgc tattgtattt ggtcgtacca aacgccgtgt
     8281 ggatgaattg actcgtggtt tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga
     8341 cctagaccaa aacaaacgtc ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt
     8401 tttggttgcg acagacgttg cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta
     8461 caactacgat attccacaag atcctgagag ttatgttcac cgtatcggtc gtacaggtcg
     8521 tgctggtaag tcaggtcaat ctattacttt tgttgctcca aacgaaatgg gttaccttca
     8581 aatcattgaa aacttgacta agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga
     8641 atccttccaa tcaaaaaaac aggtagctct caagaaaatc gaacgtgatt ttgcagatga
     8701 aaccattcgt gccaactttg agaaatttgg taaggatgct cgcaaattgg ctgctgagtt
     8761 tactccagaa gaattggcaa tgtatatctt gagtctgaca gtccaagacc cagatagcct
     8821 tccagaagtg gagattgcac gtgaaaaacc actaccgttt aaaccatcag gtaatggttt
     8881 cggtggtaaa gctaagggag gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga
     8941 tcgccgtggc aatggtcgcc gtgatgagtt caaaaaagga agtcgtggca acgatcgttt
     9001 tgataaggaa aaacgttacc gtaaggataa taaaaaacca cgcaatactt taagcgaaaa
     9061 gcaaacaggc tttgttattc gtaacaaggg cgataaataa gaaaaagcgg ttcaaaatga
     9121 atcgcttttt tatataagga gaccgaatgt gaaaagacaa ataaaattat tatattatct
     9181 tttataatgt tatgatacac aaaaataggc aacttgtcaa tagaaaagga acaatttaat
     9241 taaaaatatt ctggttttta attaaattgt aagtcaatgc aagtcaataa ggaattttca
     9301 gataattatt gaaaaagaga cgtttttatg ttataatgat agcgattaaa ttcgaggtga
     9361 aaaatggcac atttattaga aaaaactaga aaaattacat caattttgaa acgctcagag
     9421 gagcagttgc aggatgagct cccttacaac gctattacgc gtcagttagc ggatattatt
     9481 cattgcaatg cctgcattat caatagtaag ggacgtctgc ttggctattt tatgcgttat
     9541 aaaacaaata cagatcgcgt agagcaattc ttccaaacta agattttccc agatgactac
     9601 gttcaagggg ctaatatgat ttacgaaaca gaagcaaact tgcctgttga gcatgatatg
     9661 agtattttcc ctgttgagag tagagatgat tttccagatg gcttgacgac tattgcaccg
     9721 attcatgtat cggggattcg ccttggttct ttgattattt ggcgtaatga taaaaaattc
     9781 gaagatgagg acttggttct tgttgagatt gccagtaccg ttgttgggat tcagcttctt
     9841 aacttccaac gtgaagaaga tgagaaaaat attcgtcgtc gtactgctgt caccatggcg
     9901 gtcaataccc tttcttactc cgaactccgt gctgtttcag caattttagg ggaattaaat
     9961 ggaaatgaag ggaagttgac tgcgtcagtg attgcagatc gtatcggaat cactcgctct
    10021 gtgattgtca atgctcttcg taaacttgag tctgcgggga ttattgaaag tcgctcactt
    10081 ggaatgaagg gaacctatct taaggtcttg atttcagata tttttgaaga agtgaagaaa
    10141 agagattact aatgacaaag gctttaattt cgattgatta tacagaagat tttgttgctg
    10201 atagtgggaa gctgacagca ggtgctccag ctcaggcgat ttcggatgcc atcagcaagg
    10261 taactcgatt agcttttgaa cgaggagatt atatcttctt tactattgat gctcatgaag
    10321 aaaacgattt tttccatccg gaaagtaagt tatttcctcc tcataatctg attgggacga
    10381 gtggacggaa tttatatgga gatttgggga tcttttatca agagcatggt tcagacagtc
    10441 gtgtcttttg gatggataaa cgccattact cagctttttc agggactgac ctagatattc
    10501 gtttgagaga gcgtagagtg tctaccgtta tcttaacagg tgtcttgacg gatatctgtg
    10561 tcctacatac agctatagat gcctataatc taggatatga catcgagatt gttaaaccag
    10621 ctgttgcttc catctggcct gaaaatcatc aatttgccct aggtcatttc aaaaatacac
    10681 tcggagctaa gttagtagat gaaaatctaa atgaactttc tgagtaacct ggttggtgaa
    10741 aatgaaaaaa tttgaaaaaa agtgttgaca agcatcccaa aagttgatat actagtaaag
    10801 taatcgatgc ggggatggcg gaattggcag acgcgcagga ctaaggatcc tgtgaccgct
    10861 ttaggtcgtg agggttcaag tccctctctc cgcataggaa aagagttagc taaagctagc
    10921 tcttttgtat ttctctaaaa aattagaatc cagtcaaatg tagtggagaa tcagcgaaaa
    10981 tatgggaaaa ctgatccttg tttctgcttt tgtcatagaa gaataataaa ttcaaattct
    11041 ccgatattct ctaaagtttt gtgcaagttg cacagaactt ttttattttt ttggtcatct
    11101 tgccatagaa atataaagcg ttttcatcta taatataatt atcaaaagac aaaaggagtt
    11161 cacctcatgg tagaattgaa tcttaaaaat atttacaaaa aatatccaaa cagcgaacac
    11221 tattcagttg aagatttcaa cttgaacatc aaagataaag aatttatcgt tttcgtagga
    11281 ccttcaggat gtggtaaatc aactacactc cgtatgattg ctggtcttga agacattaca
    11341 gaaggtactg catctatcga tggcgtggtt gtcaacgacg tagctccaaa agaccgtgat
    11401 atcgccatgg tattccaaaa ctacgctctt tacccacaca tgactgttta tgacaacatg
    11461 gctttcggtt tgaaattgcg taaatacagc aaagaagaca ttaacaaacg tgttcaagaa
    11521 gcagctgaaa tacttggatt gaaagaattc ttggaacgta aaccagctga cctttcaggt
    11581 ggtcaacgtc aacgtgttgc catggggcgt gcgattgtcc gtgatgcgaa agtattcttg
    11641 atggacgaac ctttgtcaaa cttggatgcc aaacttcgtg tatcaatgcg tgctgaaatc
    11701 gctaaaattc accgtcgtat cggagctaca actatctatg taactcacga ccaaacagaa
    11761 gcgatgacac ttgcagaccg tatcgttatt atgtcagcta ctaagaaccc tgctggtaca
    11821 ggtactatcg gacgtgtaga acaaatcggt actcctcaag aagtttacaa aaatccagtt
    11881 aacaaatttg ttgcaggatt catcggaagc ccagctatga atttcatcaa cgtgaaattg
    11941 gttggtagcg aaattgtttc tgacggtttc cgtttgaaag tgccagaagg agcattgaaa
    12001 gttcttcgtg aaaaaggcta cgaaggaaaa gaattgatct ttggtatccg tccagaagac
    12061 gtgaatgcag aacctgcttt ccttgaaaca ttcccagact gtgttgtaaa agcgactatc
    12121 tctgtatcag aactgcttgg ttcagaatct cacctttact gccaagttgg taaagacgag
    12181 tttgttgcaa aagttgatgc tcgtgactac ttgcaaacag gtgcaacagt tgagcttgga
    12241 tttgacttga acaaagcaca cttcttcgat gtagaaactg aaaaaacaat ctactaaaat
    12301 aaataaaatt caaagcacta caagaaaaga tatctcttta tcaattgtag tggagagata
    12361 tcagttaatc tagggagaga aacaaaatgc ttctctcctt tttgctaggg aagtcatatt
    12421 atgcatctat attgtgatgc tctttaatac tcttcgaaaa tctcttcaaa ccacgtcaac
    12481 gtcgccttgc cgtacgtatg attactgatt tcgtcagttt tatctgcaac ctcaaagatg
    12541 tactttgagc agcttacggc tagtttccta gtttgctctt tgatttccat tgagtattat
    12601 ttgtgggtac catctacaag tgaagctata tgcgtaaact acgtgagcaa ttgaattcga
    12661 actagagagg taataataaa tttatgctat agttatggtg acttgtatgc ttttgattct
    12721 agtttatcaa ataatagatt agaattgtca gataatatca ttttgtgtta taatgaagaa
    12781 aaaacagagg tgttcaaatg tcagaagcag gtcataagtt tttagcaaaa ttggggaaaa
    12841 aacgcttacg tccaggtgga aagcgtgcca cagattggtt aattgcagaa ggaggatttt
    12901 caaaagaaaa gagaatacta gaggttgcgt gtaatagggg aactacagca attgagttgg
    12961 cacagcgttt tggttgtaag ataactgctg ttgatatgga tgctcaagct ttagaagtgg
    13021 ctaaaaaatc tgctggaacg gcaggtgttg ctcatttaat cagttttgaa agagcaaatg
    13081 caatgaaact tccttatcaa gatgctagtt ttgatattgt tataaatgaa gctatgctga
    13141 ctatgcaagc cgatcaagct aagaaaaaat gtgtaatgga atatctaagg gtattaaaac
    13201 ctggaggtct tctattgacg catgatgtgc ttcttaagga agctaaagag tctatcagac
    13261 aggaattatc acaagcaatt catgtaaatg taggtccttt aactcaagat ggttgggaac
    13321 aggtgatgat agaatcaggt tattgtgatg tgaaagtatt gactggtgaa atgacattaa
    13381 tgagattatc gggtatgatt tatgacgaag gtttgctagg aactttgaaa atttgtgtaa
    13441 atgcttgtaa aaaggagaat agaaagcagt ttttaactat gtataaaatg tttgctaaga
    13501 ataaacagaa attgggcttt attgcgatgg ctagttataa atcgtcaaaa cgttagataa
    13561 ttattgaagt taacttttcc ttttttcttt cttaaaaaat atgctataat agagagtaaa
    13621 aaactttgaa agaaagaaaa agatgaattt aaaagattac attgcaacaa ttgaaaatta
    13681 tccaaaggaa ggcattacct tccgtgatat tagtcctttg atggctgatg gaaatgctta
    13741 tagctacgct gttcgtgaaa tcgttcagta tgctactgac aagaaagtcg acatgatcgt
    13801 gggacctgaa gctcgtggat ttatcgtggg ttgtccagtt gcctttgagt tgggaattgg
    13861 ttttgcgcct gttcgtaagc caggtaaatt gccacgcgaa gttatttctg ctgactatga
    13921 aaaagagtac ggtgtcgata ccttgactat gcacgcggat gccattaagc caggtcaacg
    13981 tgttcttatt gtagatgacc ttttggcgac aggtggaact gttaaggcaa ctatcgagat
    14041 gattgaaaaa cttggtggtg ttatggcagg ttgtgccttc cttgttgaat tggatgaatt
    14101 gaacggccgt gaaaaaattg gtgactacga ctacaaagtt cttatgcatt attaatgaaa
    14161 acagtcccta gggctgtttt ctctacacta ggatataaaa atagactata actagttaga
    14221 gaaaaactat aattgaaaac tatatcttct tgcagtataa taaaaggact aagtgtttga
    14281 gatttgtctt caaacatatg caattattcc tgaaagagta cagttaggag agggttatgc
    14341 cgattcgaat tgataaaaaa ttgccagctg ttgagatttt acggacagag aatatctttg
    14401 tcatggatga tcaacgtgct gcccaccaag atatccgtcc tttgaagatt ttaattttaa
    14461 atctcatgcc acagaaaatg gtcacagaga cccagttgtt gcgccacttg gctaatacac
    14521 ccctacaact ggatattgat tttctctata tggagagcca ccgttctaaa acaactcgtt
    14581 cagagcacat ggagaccttc tataaaactt ttcctgaagt caaggatgag tattttgatg
    14641 ggatgatcat cacgggtgct ccagttgagc atttaccatt tgaggaagtg gactattggg
    14701 aggaatttag acagatgctt gagtggtcta agactcatgt ctattcgacc cttcatatct
    14761 gttggggggc tcaggctggg ctttatctgc gctatggtgt agaaaaatac cagatggaca
    14821 gtaagctatc aggtatttat cctcaggaca ccctaaaaga gggtcacctt ctatttagag
    14881 gctttgatga tagctatgta tcccctcatt cacggcacac ggagatttct aaggaagagg
    14941 tcttaaacaa gaccaatctc gagattttat cagaaggacc tcaggttggg gtttctattt
    15001 tggccagtcg tgatttacga gaaatttata gttttggtca tttggagtat gaccgtgata
    15061 ccttggcaaa agagtatttt cgagatcgtg atgcaggttt cgacccacat attccagaaa
    15121 attactttaa agatgatgat gttaatcagg taccttgtct ttgttggtct tcatctgcag
    15181 ccctcttttt cagtaattgg gtaaaccatg cggtctatca ggagacgcct tttgactgga
    15241 gaaagataga agatgatgca tctgcatata ggtatttata agaggaatta tgacatattt
    15301 agacgctttt aaatcaggta ccttggtttt accgagtgcc ctgctcttgc attttaagga
    15361 actctttcct tctagcgacg attttctggt ttggcaattt ttctatttgc aaaatacgac
    15421 aggcttagaa gaaatatcgc caagccagat tgctgaaagg attggcaagg aaatttcgga
    15481 tgtcaaccag tccatttcta atctgacgga aaggggactg ctccagtatc gtactatcga
    15541 attaaatggc gaaattgaat tgctctttga tgctagtttg gccttggaac gtttggatga
    15601 cctgtttgga gcagttcatt caagttcaga ccagctaaca ccacaaaacc agctcaagga
    15661 tttggtggaa accttccagc aggagttggg acgattgttg acgccttttg agattgagga
    15721 tttgaccaag acactaaagg aagatggaac cagtgctgac ttgattaagg aggctcttcg
    15781 tgaagctgtt ttgaacggaa aaccaaactg gaagtacatt caggcgattt tgagaaactg
    15841 gcgccatgaa ggaatcaaga gtgtggctca aattgaggcc aagagagcag aaagagaagc
    15901 aagcaatcct cagttgacac aggtatctgc agatttcata aatgccatgg atctctggaa
    15961 ggattaatcc atgcaagtag gcttgaaatc cgagtaagat ttgcaagctg tgtataattg
    16021 tgatagaata aatagaaaat aaattgaaaa aagaggtatg tgaaatgtca cgtaaaccat
    16081 ttatcgctgg taactggaaa atgaacaaaa atccagaaga agctaaagca ttcgttgaag
    16141 cagttgtatc aaaacttcct tcatcagatc ttgttgaagc aggtatcgct gctccagctc
    16201 ttgatttgac aactgttctt gctgttgcaa aaggctcaaa ccttaaagtt gctgctcaaa
    16261 actgctactt tgaaaatgca ggtgctttca ctggtgaaac tagcccacaa gttttgaaag
    16321 aaatcggtac tgactacgtt gttatcggtc actcagaacg ccgtgactac ttccatgaaa
    16381 ctgacgaaga tatcaacaaa aaagcaaaag caatctttgc gaacggtatg cttccaatca
    16441 tctgttgtgg tgaatcactt gaaacttacg aagctggtaa agctgctgaa ttcgtaggtg
    16501 ctcaagtatc tgctgcattg gctggattga ctgctgaaca agttgctgcc tcagttatcg
    16561 cttatgagcc aatctgggct atcggtactg gtaaatcagc ttcacaagac gatgcacaaa
    16621 aaatgtgtaa agttgttcgt gacgttgtag ctgctgactt tggtcaagaa gtcgcagaca
    16681 aagttcgtgt tcaatacggt ggttctgtta aacctgaaaa tgttgcttca tacatggctt
    16741 gcccagacgt tgacggtgcc cttgtaggtg gtgcgtcact tgaagctgaa agcttcttgg
    16801 ctttgcttga ctttgtaaaa taatcagtaa gtagcaaaag ctaggtggaa cagcattcag
    16861 atgtctgtta cattttttat aggagaggaa agattgaaaa taaaaattgg attagcaagt
    16921 atctgtttac taggcttggc aactagtcat gtcgctgcaa atgaaactga agtagcaaaa
    16981 acttcgcagg atacaacgac agcttcaagt agttcagagc aaaatcagtc ttctaataaa
    17041 acgcaaacga gcgcagaagt acagactaat gctgctgccc actgggatgg ggattattat
    17101 gtaaaggatg atggttctaa agctcaaagt gaatggattt ttgacaacta ctataaggct
    17161 tggttttata ttaattcaga tggtcgttac tcgcagaatg aatggcatgg aaattactac
    17221 ctgaaatcag gtggatatat ggcccaaaac gagtggatct atgacagtaa ttacaagagt
    17281 tggttttatc tcaagtcaga tggggcttat gctcatcaag aatggcaatt gattggaaat
    17341 aagtggtact acttcaagaa gtggggttac atggctaaaa gccaatggca aggaagttat
    17401 ttcttgaatg gtcaaggagc tatgatgcaa aatgaatggc tctatgatcc agcctattct
    17461 gcttattttt atctaaaatc cgatggaact tatgctaacc aagagtggca aaaagtgggc
    17521 ggcaaatggt actatttcaa gaagtggggc tatatggctc ggaatgagtg gcaaggcaac
    17581 tactatttga ctggaagtgg tgccatggcg actgacgaag tgattatgga tggtactcgc
    17641 tatatctttg cggcctctgg tgagctcaaa gaaaagaaag atttgaatgt cggctgggtt
    17701 cacagagatg gtaagcgcta tttctttaat aatagagaag aacaagtggg aaccgaacat
    17761 gctaagaaag tcattgatat tagtgagcac aatggtcgta tcaatgattg gaaaaaggtt
    17821 attgatgaga acgaggtgga tggtgtcatt gttcgtctag gttatagcgg taaagaagac
    17881 aaggaattgg cgcataacat taaggagtta aaccgtctgg gaattcctta tggtgtctat
    17941 ctctatacct atgctgaaaa tgagaccgat gctgagaatg acgctaaaca gaccattgaa
    18001 cttataaaga aatacaatat gaacctgtct taccctatct attatgatgt tgagaactgg
    18061 gaatatgtaa ataagagcaa gagagctcca agtgatacag acacttgggt taaaatcatc
    18121 aacaagtaca tggacacgat gaagcaggcg ggttatcaaa atgtgtatgt ctatagctat
    18181 cgtagtttat tacagacgcg tttaaaacac ccagatattt taaaacatgt aaactgggta
    18241 gcggcctata cgaatgcttt agaatgggaa aacccttatt attcaggaga aaaaggttgg
    18301 caatatacct cttctgaata catgaaagga atccaagggc gcgtagatgt cagcgtttgg
    18361 tattaagcga tgatttgaaa gagggatgtg atagtagcac cctctttttc tttgttttat
    18421 gatagttcat cctcgagtaa attcaagatc ttgctcggaa atgaagctta tatagtagat
    18481 tgaatataga caaatacctt gtgattggta aaacatttta gaaattcatt tacctttcct
    18541 aatcgacttg gtttcatctt atttcaatct attatagtat tggggaattt cttcaaacca
    18601 catcagcttg gtcagttcta cctgcgacct caaaacttgt gctttggtca agctgggttt
    18661 agtttcctag tttgctgatg gatttccatt gactataagc atccaaccct ctttttgtct
    18721 tctaaagaat tcttaaatta tcagtctatt gcaacttttc tcatataagt tctttgtctt
    18781 gctattggtt ttccttagta gtatactaag gtagtaatca ttaagaagtg gttacaaaaa
    18841 ataatgaatg aggtaaagaa aatggtagaa ttgaaaaaag aagcagtaaa agacgtaaca
    18901 tcattgacaa aagcagcgcc agtagcattg gcaaaaacaa aggaagtctt gaaccaagct
    18961 gttgctgatt tgtatgtagc tcacgttgct ttgcaccaag tgcactggta tatgcatggt
    19021 cgtggtttcc ttgtatggca tccaaaaatg gatgagtaca tggaagctct tgacggtcaa
    19081 ttggatgaaa tcagcgaacg cttgattaca ctcggtggaa gcccattctc tacattgaca
    19141 gagttccttc aaaatagtga aatcgaagaa gaagctggtg aataccgtaa tgttgaagaa
    19201 agcttggaac gtgttcttgt tatctaccgt tacttgtcag aacttttcca aaaaggtttg
    19261 gatgtcactg atgaagaagg tgacgatgtg acaaacggta tctttgcagg cgctaaaact
    19321 gaaacagata aaacaatttg gatgcttgca gccgaacttg gacaagcacc tggtttgtaa
    19381 gaaataagga aacatagata aatctgtagg aaatttctta cagatttttt ctattttgta
    19441 agctattcca aaccagtctt tttttgagtt ttttgataaa atagtactat cagtgaaaag
    19501 gatggaagca tgactaagaa aatcgtagct atttgggccc aggatgaaga gggtgtgatt
    19561 ggtaaggaca atcgtctgcc ttggcatttg ccagcagaat tgcagcactt taaagaaaca
    19621 actctgaatc atgctatctt gatggggcgt gtgacctttg atgggatggg gcgtcgcttg
    19681 cttccaaaac gggaaaccct gattttgacg cgtaatccgg aagaaaagat agatggggtt
    19741 gctacttttc aggacgtcca gtctgttctt gactggtatc aggctcaaga aaagaatctc
    19801 tacattatcg gtgggaagca aatttttcag gcttttgaac cttaccttga tgaagtgatt
    19861 gtcactcaca ttcatgctcg ggtggaagga gatacctatt tccctgaaga acttgacttg
    19921 tctctttttg agacagtttc aagcaaattt tacgccaaag atgagaagaa tccttatgat
    19981 tttaccatcc aataccgcaa gagaaaggaa gtctaatgga acggagttta tttggtctat
    20041 tcacggcttt tctgtgtttc atctgctttc tggcaggagc acaggctttt cgtaaaaagc
    20101 gttacgggct ttctatcctc ctttggttaa atgcctttac caatctggtc aatagtattc
    20161 atgcttttta catgacctta ttttagatag aatgacagta tagaatggaa ggaaatcatg
    20221 tctacaaata gaaaaaatga tatgatggtt tattgctcat tttgtggcaa aaaccaagaa
    20281 gaagtacaaa aaataattgc tggcaacaat gcttttattt gtaatgaatg cgtggagtta
    20341 gctcaggaaa tcattcgaga agaattggtt gaggaagtct tggcagactt gtctgaggtg
    20401 ccaaaaccaa ttgaactcct ccatatcttg aaccactatg taattggtca agatcgtgcc
    20461 aagcgtgcct tggcagtggc ggtttataac cactacaaac gcatcaattt ccacgataca
    20521 cgcgaagagt cagaagatgt ggatttgcag aagtcaaaca ttttgatgat tggcccaact
    20581 ggttcaggga aaactttcct tgcccagacc ttggctaaga gcttgaatgt accttttgct
    20641 attgcggatg cgacagctct gacggaggct ggttatgtgg gtgaggatgt ggaaaatata
    20701 ctcctcaaac tcttgcaggt tgctgacttt aacatcgaac gtgcagagcg tggcattatc
    20761 tatgtggatg aaattgacaa gattgccaag aagaatgaga atgtgtctat cacacgtgat
    20821 gtttctggtg aaggggtgca acaagccctt ctcaagatta tcgagggaac tgttgctagc
    20881 gtaccgcctc aaggtggacg caaacatcca caacaagaga tgattcaagt ggatacaaaa
    20941 aatatcctct tcatcgtggg tggtgctttt gatggtattg aagaaattgt caaacaacgt
    21001 ctgggtgaaa aagtcatcgg atttggtcaa aacaataagg cgattgacga aaacagctca
    21061 tacatgcaag aaatcatcgc tgaagacatt caaaaatttg gtattatccc tgagttgatt
    21121 ggacgcttgc ctgtttttgc ggctcttgag caattgaccg ttgatgactt ggttcgcatc
    21181 ttgaaagagc caagaaatgc cttggtgaaa caataccaaa ccttgctttc ttatgatgat
    21241 gttgagttgg aatttgacga cgaagccctt caagagattg ctaataaagc aatcgaacgg
    21301 aagacagggg cgcgtggact tcgctccatc atcgaagaaa ccatgctaga tgttatgttt
    21361 gaggtgccga gtcaggaaaa tgtgaaattg gttcgcatca ctaaagaaac tgtcgatgga
    21421 acggataaac cgatcctaga aacagcctag aggtgactat ggaacttaat acacacaatg
    21481 ctgaaatctt gctcagtgca gctaataagt cccactatcc gcaggatgaa ctgccagaga
    21541 ttgccctagc agggcgttca aatgttggta aatccagctt tatcaacact atgttgaacc
    21601 gtaagaatct cgctcgtaca tcaggaaaac ctggtaaaac ccagctcctg aactttttta
    21661 acattgatga caagatgcgc tttgtggatg tgcctggtta tggctatgct cgtgtttcta
    21721 aaaaggaacg tgaaaagtgg gggtgcatga ttgaggagta cttaacgact cgggaaaatc
    21781 tccgtgcggt tgtcagtcta gttgaccttc gtcatgaccc gtcagcagat gatgtgcaga
    21841 tgtacgaatt tctcaagtat tatgagattc cagtcatcat tgtggcgacc aaggcggaca
    21901 agattcctcg tggtaaatgg aacaagcatg aatcagcaat caaaaagaaa ttaaactttg
    21961 acccaagtga cgatttcatc ctcttttcat ctgtcagcaa ggcagggatg gatgaggctt
    22021 gggatgcaat cttagaaaaa ttgtgaggaa aagaaaatgg caaaaacaat tcatacagat
    22081 aaggccccaa aggctatcgg gccctatgtt caaggaaaaa tcgttggcaa ccttttgttt
    22141 gctagcggtc aagttcccct atcccctgaa actggggaaa ttgtaggaga gaatatccaa
    22201 gaacagacag agcaagtctt gaaaaacatc ggtgctattt tggcagaagc aggaacagac
    22261 tttgaccatg ttgtcaaaac aacttgtttc ttgagcgata tgaacgactt tgttcctttt
    22321 aatgaggttt accaaacggc cttcaaagag gaattcccag ctcgttcagc tgtggaggta
    22381 gctcgtcttc ctcgtgatgt aaaagtcgaa attgaagtca tcgcagagat tggataagct
    22441 agttgaagtt tggtgttgcc aaacttcttt tgatataagg agaaaaagat gacaaagaaa
    22501 caacttcact tggtgattgt gacagggatg agtggcgcag ggaaaactgt agccattcag
    22561 tccttcgagg atctaggtta tttcaccatt gataatatgc cgccagctct cttgcctaag
    22621 tttttgcagc tggttgaaat taaggaagac aatcctaagt tggccttggt agtggatatg
    22681 cgtagccgtt ctttcttttc agagattcaa gctgttttgg atgagttgga aaatcaagat
    22741 ggtttggatt tcaaaatcct ctttttggat gcggctgata aggaattggt cgctcgttac
    22801 aaggaaacca gacggagtca cccactagca gcagacggtc gtattttaga tggaatcaag
    22861 ttggaacgtg aactcttggc acctttgaaa aatatgagcc aaaatgtggt ggatacgact
    22921 gaactcactc cacgtgagct gcgcaaaacc cttgcagagc agttttcaga ccaagaacaa
    22981 gcccagtctt tccgtatcga agtcatgtct ttcggattta agtatggaat cccgattgat
    23041 gcggacttgg tctttgatgt ccgtttcttg ccaaatccct attatttacc agaactgaga
    23101 aaccaaacgg gtgtggatga acctgtttat gattatgtca tgaaccatcc tgagtcagaa
    23161 gacttttatc aacatttatt ggccttgatt gagccgattc tgccaagtta ccaaaaggaa
    23221 ggtaagtccg ttttgaccat tgccatggga tgtacgggtg gacaacaccg tagtgtggca
    23281 tttgctaaac gcttggtgca ggacttatcc aagaattggt ctgttaatga agggcatcgc
    23341 gacaaagacc gcagaaagga aacggtaaac cgttcatgag aaaaccaaag ataacggtga
    23401 ttggtggagg gactggaatt cccgtcattc taaaaagtct gcgggaaaaa gatgtggaaa
    23461 tcgcagctat cgtgacggtg gcagatgatg gtggttcttc aggtgaactc cgaaaaaata
    23521 tgcaacagtt gacaccgcca ggtgatcttc gtaatgtcct tgtggccatg tcggatatgc
    23581 ctaagtttta tgagaaggtc tttcagtatc ggttctctga ggatgccgga gcctttgctg
    23641 gccatccatt gggaaatctc atcattgctg gcttgtcaga aatgcagggt tcaacctata
    23701 atgccatgca gttattgagc aaatttttcc atacaacagg gaaaatttat ccttccagtg
    23761 accatccttt gacccttcat gcagtctttc aggatgggac agaagtggct ggagagagtc
    23821 atattgtaga ccatcgaggc ataattgaca atgtctatgt gaccaatgcc ctaaacgatg
    23881 atacgcctct ggccagccgt cgagtagtgc aggccatcct tgaaagtgac atgattgtcc
    23941 tagggccagg ttccctcttt acctctattt tgcccaatat cgtgattaag gaaattgggc
    24001 gggctctttt ggaaactaag gcagaaattg cctatgtctg taatatcatg acccaacgtg
    24061 gggagacgga acactttaca gatagcgacc acgtggaagt cttgcatcgt caccttggtc
    24121 gcccttttat cgacactgtc ttggtgaata ttgaaaaagt gcctcaggaa tacatgaatt
    24181 ccaaccgttt tgatgaatac ttagtgcaag tggaacacga ttttgtaggt ctttgtaagc
    24241 aagtttcgcg cgtgatttca tctaacttcc ttcgtctgga aaatggcggt gccttccacg
    24301 atggagattt gattgtggac gagttgatgc gcattataca ggtgaaaaaa tgagtttcac
    24361 agtagcagta aaagaagaaa tcctgggcca acaccatctg agctggcatg aattatctgc
    24421 cattatcaaa atgtctggta gcatcggtct ctcgacttcg ggcttgactt tgtcagttgt
    24481 gacagaaaat gccaaactgg cccgtcacct ctatgagtcc tttcttcatt tctatgaaat
    24541 caaatctgaa attcgtcacc accaacgtag caatcttcgc aagaatcgcg tctataccgt
    24601 ttttacagat gaaaaggtgc aggatttgtt aagtgatttg cacttggcag actctttctt
    24661 tggcctggaa acaggtattg atgaggcgat tttatcggat gaggaagcag gtcgtgccta
    24721 tctctgtggc gctttcttgg caaatgggag cattcgtgac cctgagtcag gcaagtacca
    24781 gttggaaatc agttctgttt atctggacca cgcgcaagga attgcctccc ttctccaaca
    24841 gtttttactg gatgccaagg tgcttgagcg caagaagggg gctgtgacct atctccagcg
    24901 agcagaagac attatggact tcttgatagt aatcggagcc atgcaggcac gtgatgattt
    24961 tgagcgggtt aagattttgc gagaaacccg taacgacctc aatcgggcta ataatgccga
    25021 gacagctaat atcgctcgga cagtttctgc cagcatgaag accattaaca atatcagtaa
    25081 aatcaaagat atcatgggct tagaaaattt gccagtagat ttgcaggaag tggcgcaact
    25141 gaggattcag cacccagact actctatcca gcagttagca gatagtctca gcacccctct
    25201 gaccaaaagt ggtgtcaatc acagactcag aaaaatcaat aagatagccg atgaattata
    25261 aaaccacgaa tcctatgtga ctcgtggttc ttttttataa actggtagag tgttttggtt
    25321 gtactttttg ttcagggtca atgtagttga tagcgttgtt gacagcagtt ggagcttctc
    25381 cgaggcctgt cgcaatcaga tcaatttttc cgtcatagta gcagcagtca ccgatagcat
    25441 agatacctgc ttggctggat tcttgtttgc tgttgacgat aatcttgtga cggttgaggt
    25501 cgagccccca gtttttaagg ttaccgacag aagatttgaa accatagttg acaaagaggt
    25561 ggtctaggtc aatggtttca gtttcatcag atttgacttt tgtgatttca agtttatcaa
    25621 gtgtttttcc atttccaagg agttggccag gggcgaatgg tgtcttgatg gttacagatg
    25681 attcttgcaa ggcttgaaca ctgtgttcca aggcacggaa attatctctg cggtgaacaa
    25741 gggtagttgg tgcgattttt tcaaaagcca aagcccaatc cacagccgag tctcccccac
    25801 caagaatcgt cactttctta ccagcgtatt gctgaatgtt agaaacgtgg tagtggatat
    25861 tttcatagcc ctcaacccct tcaagttcca gcggacgtgg tttgaaggca ccgccaccca
    25921 tagcgatgat aactgtttta gtcaggtgac ttcctttaga agttgtgatg gcaaattctt
    25981 cttgtttgtc aatctcaaga accgtttcat tgagatgaat aggggtatca aatccattta
    26041 gctgttcaat caagcggtta gtcaactctt ctccagtcag gtttgggaag cctggtacgt
    26101 ctaggatttc cttttcaggg tagagaatag caggttgtcc acctagctgg ggaagagagt
    26161 cgatgatttg aaccttggct tggcgtaggt gggcataaaa ggctgcaaaa agcccgacag
    26221 gaccaccacc cacaatggta atatcataga gttgagacat agtttctcct ttgttttttc
    26281 tagtcagttt attttatcat atttttgttc aatgtaaaat ggactaggat agggaaaaaa
    26341 atgcccgaaa atggtataat aggacgaaag tgttttgata gggaggatat cagggatgaa
    26401 ttttcaacaa ttatccaatc tgcaatattg gaccagtttg tttgcaagtc catggacgat
    26461 agctatcaat ctgattgata ttttgattgt tgcttatatt ttataccatt ttacaaaagc
    26521 tattgcagga accaagatta tgattttggt acgtggagtt ttggtattta ttttagctca
    26581 aatccttgca aatatgattg gtttgactac gatttcttgg ttaatcaatc aaattattac
    26641 ttatggggtt attgcggcgg ttgttatctt ctctccagag attcggactg gtttggaacg
    26701 tttgggaaga gcgacagatt tcttttccaa tgcccctatt agtgctgagg aacagatgat
    26761 tcgtgccttt gttaagtctg ttgaatacat gagtcctcgt aaaatcgggg ccttggttgc
    26821 tattcagcgt gtacgtacct tgcaggagta tatttcgaca ggaattccct tggatgctaa
    26881 gatttctgca gaacttctca ttaacatttt tattcccaac actcccctac atgacggtgc
    26941 ggtgattatc aaagaagaac gtatcgctgt gacgtctgcc tatctgccct tgacaaaaaa
    27001 cacagggatt tccaaggaat ttgggaccag acaccgggcg gctatcggtt tatcagaagt
    27061 ctcagatgcc ttgacttttg tcgtatcaga ggaaacggga ggaatttcga taacctataa
    27121 tggaaggttt aagcacaacc taacacttga tgaatttgaa acagaattac gtgaaatctt
    27181 acttccaaaa gaggaagtgg gtcttagttt taaagaacga ttgctaggag gatggaaaca
    27241 tgaaaaaaaa tagtttatat atcatatcct cactcttttt tgcttgtgtc ttatttgtct
    27301 atgctacggc gacgaatttt caaaacagta ccagtgctag gcaggtaaaa acggaaacct
    27361 atactaatac agtaacaaat gtccctattg acatacgcta taatagtgat aagtatttta
    27421 ttagcggttt tgcttcagaa gtatcagtgg tcttgactgg tgcaaatcgc ctatcgctag
    27481 ctagtgaaat gcaagaaagt acacgtaaat tcaaggttac tgctgaccta acagatgccg
    27541 gtgttggaac gattgaagtt cctttgagca ttgaagattt acccaatggg ctgaccgctg
    27601 tggcgactcc gcaaaaaatt acagtcaaga ttggtaagaa ggctcagaag gataaggtaa
    27661 agattgtacc agagattgac cctagtcaaa ttgatagtcg ggtgcaaatt gaaaatgtca
    27721 tggtgtcaga taaagaagtg tcgattacga gtgaccaaga gacattggat agaattgata
    27781 agattatcgc tgtcttgcca actagcgaac gtataacagg taattacagt ggttcagtac
    27841 ctttgcaggc aatcgaccgc aatggtgttg tcttaccggc agttatcact ccgtttgata
    27901 caataatgaa ggtgactaca aaaccagtag caccaagttc aagcacatca aattcaagta
    27961 caagcagttc atcggagaca tcttcgtcaa cgaaagcaac tagttcaaaa acgaattaaa
    28021 aatagaaaag gattttataa caatgggtaa atattttggg actgatggag tccgtggaga
    28081 agctaaccta gaactaacac cagaattagc ctttaaacta ggacgttttg gaggctatgt
    28141 tcttagtcaa catgaaacgg aagcgccgaa agtctttgta ggacgtgaca cacgtatttc
    28201 aggggaaatg ctggaatcgg ccttggtggc aggtctcctt tcagtaggga ttcacgtata
    28261 caaacttggt gtccttgcaa caccagcagt agcttacttg gttgaaactg aaggagcaag
    28321 tgccggtgtc atgatttctg ctagccacaa cccagccctt gataacggaa tcaagttctt
    28381 tggcggtgat ggcttcaaac tagatgatga aaaagaagca gaaattgaag ccttgctaga
    28441 tgctgaggaa gacactcttc ctcgtccaag tgcagaaggc ttaggaattt tggtagatta
    28501 tccagaaggc ttgcgtaagt atgaaggata ccttgtttca actggaactc ctcttgatgg
    28561 aatgaaggtt gccttggata cagctaatgg agcagcttct accagtgccc gtcaaatctt
    28621 tgcagacctt ggtgcccaat tgacggttat cggggaaaca ccagacggtc ttaacatcaa
    28681 ccttaatgtt ggttcaacac atccagaagc ccttcaagaa gtggtcaaag aaagtgggtc
    28741 agctattggt ttggcctttg atggagacag tgaccgcttg attgctgttg atgagaatgg
    28801 tgacatcgtc gatggtgaca agattatgta tatcatcgga aaataccttt ctgaaaaagg
    28861 acaattggct caaaatacaa ttgtgacaac tgttatgtct aaccttggtt tccacaaggc
    28921 cttgaatcgc gaaggtatta acaaggcagt tactgcagtt ggtgaccgct acgttgttga
    28981 agaaatgaga aaatcaggct acaaccttgg tggtgaacag tctggtcacg ttatcttgat
    29041 ggattacaat accacaggtg atggtcaatt atcagcagtt caattgacta aaatcatgaa
    29101 ggaaactggt aagagcttat cagagttggc ggcagaagta acgatttatc cacaaaaatt
    29161 agttaatatc cgagtggaaa acgtcatgaa ggaaaaggcc atggaagtgc cagctatcaa
    29221 gaccatcatc gagaagatgg aagaagaaat ggcggggaac ggccgtatcc ttgttcgtcc
    29281 aagtggaaca gagcccctct tgcgtgttat ggcagaagcg cctacaatag aagaagtgga
    29341 ctactatgtt gataccatca cagatgtagt tcgtgctgaa attgggattg actaaatcct
    29401 agaaaactag atgaaaataa aaaattatgg tacaatagct tataatattg tagccgatgg
    29461 agaaagacat gaatcttaaa cgtgaacaag aatttgttag tcagtatcat tttgatgcgc
    29521 gtaattttga atgggaaaat gaaaatggag ctcctgaaac caaggtggat gtgaatttcc
    29581 aattgctcca acatgaccaa gaaaatcaag tgacttcctt gattgtcatc ttgagcttta
    29641 tgattgtatt tgataagttt gtcattagtg gaacaatctc acaagtaaac catatcgatg
    29701 gccgtattgt caatgaacca agtgaattga accaagaaga ggtggaaacc ttggctcgtc
    29761 catgtttgaa catgctcaat cgtttgactt acgaagtgac tgaaattgca ttagacttac
    29821 caggaattaa tttggagttc taatatgaaa ttagctgttt tcacagattc ctctgcttat
    29881 ctcagtgaag agaccttgca aagagaagac ttgtttgtct tggatattcc tgtcaatatt
    29941 gatggtgagg aatatgtcga aggcatcaat ctgtctgctg aggaatttta ccaaaaaatg
    30001 gctcaggctt ctgaattgcc taagaccagt caaccaagta ttgccaagtt agatgagatc
    30061 ttaacttcgc tcaaagaaca aggctataca catgccttgg ggcttttcct atcttctgga
    30121 atttcaggtt tttaccaaaa tatccagtat atggtcgatg actatgaggg cttaaccatt
    30181 gctttcccag acactttgat tacaagtgct cccctaggca tcatggttga aagcgtcttt
    30241 aattggcgtg atcagggcga tgattttgcc agcattcagg ataagctagc cattcaaatc
    30301 agccgtacgt cagcctttat catggtagat gacttggatc atttggtaaa aggtggacgc
    30361 ctttcaaatg gggctgccat tttgggcaat ttgcttagca ttaagccaat cctttatttt
    30421 aacgatcaag gtgtgattga agtttacgaa aaagttcgta ctgaaaagaa ggccaccaaa
    30481 cgcttaattg aaattatcaa ggaaacaacg gcttcaggtc aataccgggt cattgtcatt
    30541 catgggaatg ctcctgaaaa ggctgaagaa ttgcgtcagc atttgcttga ttttggcttg
    30601 ggttcggatg tttcacttgc tacatttggt agtgtcattg gaacgcacct aggagcagga
    30661 agtattgctc tgggttatat tccagtgatt tagtaggcac ttctaggcta gttaatctta
    30721 gcaattgaac acggactacc tgcctcttga aaaaagatgt ctgtcttgcc tttcgtggaa
    30781 agtcagtgcc attccctatt tttcatgggt ggctaagatc ctttgtattt tgataattga
    30841 acacgcctgg aaccctgtgt gaaaaagata gttcttccaa ggagtagaca cttcttgatc
    30901 agaattccta ttttcacttt gtgttcttac aggctttgta tcttagacag gagtagagat
    30961 gagtattcga gtaattattg ccggttttaa gggaaagatg ggtcaagctg cttgccagat
    31021 ggtcttgcct gattcagatt tggacttggt agcagttttg gatccttttg agtctgagtc
    31081 agaatggcag ggtattcctg ttttcaagga taaggctgat ttagctggtt ttgaagcgga
    31141 tgtctgggta gactttacta ctccagctgt tgcctacgaa aatacacgtt ttgctcttga
    31201 aaatggcttt gctccagtag ttggaacgac tggtttcacg agtgaagaaa ttgcagagct
    31261 aaaagaattt tctcgtgccc aagacttggg tggcctgatt gcccctaact ttgccttggg
    31321 tgctgtctta ctcatgcaat ttgcgacgca ggctgccaaa tatttcccaa atgtggagat
    31381 tattgagctc catcatgaca agaaaaagga tgctccgagt ggaacagcca ttaaaacagc
    31441 tgagttgatg gcagaggttc gagagtcaat tcagcaaggt gcagcagatg aggaagagct
    31501 gattgctggt gctcgtggtg ctgactttga tggtatgcgc atccactcag ttcgtttgcc
    31561 aggcttggta gctcatcagg aagtcatctt tggcaatcag ggagaagggt tgaccctccg
    31621 tcatgactcc tatgatcgca tctccttcat gacaggagtc aatttgggaa ttaaagaagt
    31681 tgtcaagcgt catgagcttg tctatggatt agaacactta ttatgagatt aacgcaaatg
    31741 ccttctgaat ttcagaaggc tttaccagta ttagaaaaaa ttaaagaagc aggctttgag
    31801 gcttattttg ttgggggctc tgttcgagat gcccttctcc atagccctat ccacgatgtg
    31861 gatattgcga cgtcttctta tccagaagag accaagcaga tttttccgcg aacagccgat
    31921 atcggaatcg agcatggaac cgtcttggtc ttagatgggg atgaggagta tgaggtaaca
    31981 acctttcgga cagaggatgt ctatgtggac tatcgcagac ccagtgcggt ttcctttgtg
    32041 cgctcgctag aagaagacct caaacgccgt gatttcacag tcaacgcctt tgccttggat
    32101 gagacaggag aaatcgttga cttgttccat ggtttagaag atttggaaaa gcaagtcttg
    32161 cgagcagttg gagtggctag tgagcgtttc aacgaagatg ctttacggat tatgcgtggt
    32221 ttccgttttc aggctagtct tggttttgca cttgagccag aaacatttaa agctatgaag
    32281 accttgacgc cgcttttgga gaaaatttct gtagagcgta ccttcgtcga atttgataaa
    32341 ctcttgctgg ctccattttg gagaaggggc ttggcttcca tgattgagag tcaagcttat
    32401 gactatctcc ctgatatggc atctagccag gacaagctca acagactgtt tgatttggag
    32461 actgatttta cttttgaatc ctctgaacaa gcctgggcgg ctttactatg ggctttggag
    32521 attgaaaatg cgcagtcatt tttgaaatct tggaagacct cacgccagtt tgccaagcaa
    32581 gttcaggatt tgctgattat tttggctctg cgtgaaaatg gagaattgag caagcgagat
    32641 tgttatcgct ttgacataga tttgctttta caggctgaaa atcttcgtca agctcaagga
    32701 aaagaagtca acccacaagc catcacagaa aaataccaaa gcttgactat ccatgacaag
    32761 aaagagattc agattaatgg cgatattttg atcaaggaat atggctatca gccaggccca
    32821 gacttgggag agattttaac agagattgag tttgccattg tcgatggaga attggagaat
    32881 aatcgtgaag ccatccatgc ttacctgagg gagaaaaaat gagtgatttt atcgttgaaa
    32941 aactaagtaa atccgttggt gacaagaccg tttttaggga tatttccttt attatccatg
    33001 acttagacag aattggttta atcggtgtca atgggactgg caagaccacc cttttggacg
    33061 tcctttctgg tgtttctgga tttgatgggg atgtcagtcc tttttcagct aaaaatgatt
    33121 accagattgg ttatttgact caggatcctg attttgatga tagaaagaca gttttggata
    33181 cggttctatc tagtgaactc aaggaaatcc agctcattcg tgagtatgaa ttgattatgc
    33241 tcgactatag tgaggacaag caggcgcgtt tggaacgtgt catggcagag atggactctc
    33301 tccaagcttg ggaaatcgag agtcaggtca agaccgttct tagcaaattg ggcattcaag
    33361 acttatctac tcctgttggg gaattgtcag gtggtctgag aagacgggta cagttggcac
    33421 aagtcttact tggcaaccac gaccttttgc ttttggatga gccgaccaac catctggata
    33481 ttgcgattat tgagtggctg accctctttt tgaaaaattc taagaagacc gtccttttta
    33541 tcactcacga tcgttatttc ttagacgctt tgtcaacacg gattttcgag ttggagcgag
    33601 caggcttgac agaatatcag ggcaattacc aggactatgt tcgccttaag gcagaacagg
    33661 acgagcgcga tgcagctcta cttcataaaa aagaacaact ctacaaacaa gaactggcct
    33721 ggatgagcag acaaccgcag gcgcgtgcga ccaagcaaca agctcgtatc aatcgtttcc
    33781 atgatctgaa aaaggaagtt tcaggcagta gtgctgagac agacttgact atgaactttg
    33841 aaaccagtcg gattgggaag aaagtcatcg agtttcaggc tgtttccttt gcctatgaaa
    33901 ataagcccat tttgcaagat tttaatctct tagttcaggt taaagaccgt attggaattg
    33961 ttggggacaa tggtgttgga aaatcaaccc tacttaacct gattgcagga agtcttgagc
    34021 cgacagcagg acaagttgtg attggggaaa ctgttcgcat cgcctatttc tctcaacaaa
    34081 ttgagggttt ggatgaaagc aagcgtgtga tcaattacct gcaggaagtg gcagaggagg
    34141 tcaagaccag tggtggttct acgacttcca tcgctgagtt gctggagcaa ttcctcttcc
    34201 cacgttcgac gcatgggacc ttgattgaga agttgtcagg gggtgagaaa aaacgtcttt
    34261 atctcctcaa actgcttttg gaaaaaccaa atgttcttct tttagacgag ccaaccaatg
    34321 acctagatat tgcaactttg acagtcttag agaatttctt gcaaggtttt gcaggtcccg
    34381 ttttaacagt cagtcacgac cgctatttct tggataaggt agcgaccaag attctcgctt
    34441 ttgaggatgg caagattcgt cctttctttg gtcattacac cgactatctt gatgaaaaag
    34501 cttttgaaac agatatggcc aatcaagtgc aaaaggccga aaaggaaaaa gtggtcaagg
    34561 ttcgagaaga caagaaacgc atgacctacc aagaaaagca ggagtgggca agtattgaag
    34621 gtgatattga aaccttggaa aaacgtatcg ctgctattga agaggaaatg caggctaacg
    34681 gctctgactt tggtaagctg gctactctcc aaaaagaatt ggatgagaaa aatgaagcac
    34741 tccttgaaaa atacgaacgc tatgagtatc tcagtgaatt tgatagttaa gactattcga
    34801 aaatcaaagt gcaaactatg tcggcttcac attgccgact caagtacagc ctgtgaccgg
    34861 cttcctaatt tgcactttga tttttattga gtataaaaga atagaaaaat cccgtctcat
    34921 gaaaggattt ctctattctt ttttggtttc ttgatgaaag atattttgcc aggtttcgtg
    34981 gcgacgccag atactggtat ggatgatacc atctaactca tagcagatga gtttggtttt
    35041 ttgactgatg gaagtaattt gaatgtcctt gatagcagaa tttaactctt ttttggtctt
    35101 ataagcctct ttatccatct gctctccatc ttggcgaata tagacaaaat catcagtcaa
    35161 gagttcttct agttggtttc cttggtcaat caattgttca cgcataagca attttttata
    35221 gacattgtct aaaatttcat cctcagggat aggtgctggt tcgatatgga catcggtatc
    35281 aaagacgcca aaacgctcct ccagcataga ctcgacctga tccgcgattt catggctttc
    35341 aaaaacagac aagtcaggat tcatctctag tgtaatatcc aggtagatgt tgctaccgta
    35401 ggtgcgacct ctttgcgatt tgaccttgct gattttggga atttccatga tagccttttg
    35461 gtagtcctcg agcaggcggt cgtcaaagcc atctgaaaga ctaaaggaag actcgatgaa
    35521 gatatcatag gcagtcttca agataaagaa agtgatgatg atagcaacca gtttatccac
    35581 aatcggataa ttgaaactac tagctaggat ggcaatggcg gttccaagtg aggtaacagc
    35641 gtcagaaaga ttgtccttag cagctgcctt cagcgccttg gagttggatt tcttactgag
    35701 gcgagtattg tagagataga ccacaaacat aatcgctgca gaaatgattc ctagagttgc
    35761 accaagagga tcaatgaccg tttcttcccg actgagaatc ttttgaatgg tatctcttag
    35821 aacatcgaaa ccgacataga acatgatgat agaagtgatc aagcttgcca aatcttcaat
    35881 cttccaatga ccaaaacggt ggtcacggtc tgcaggctgg cgcgccatcc gaatcccgat
    35941 taagagggcc acatttccaa tgatgtccga tacgttatta aaaccatcgg ccaccaaact
    36001 ggatgaatga aggagatgac cagctgctaa tttggctgca gacaagatca aataggtcga
    36061 aatactgata atggctccac gctcagctaa cttgagattt gagatagatt gcttcattca
    36121 acttcctttc tagtcacata gcattctacc attatactgg ttttcaagga aaaattcaaa
    36181 taaggcagtt tttactcttt gaaaactccc caaaatttgg tataatggta ctactcaagg
    36241 gagtagctgg cagaaacctg tgatagtgtc gtcattccga attttatgct gaaaagtatg
    36301 ctttccggcc ctatcttaaa cagcgagact tgttatgatt aacaggtctc tttttgtttg
    36361 tcgtgaaaag atatgacaga aagagagtct gttttgcaca caatgtcaag gaggagacac
    36421 atgtcaaaag aacaaaaacg ccaagcgttt tatactcaga gccctgaaga ggtcttgcag
    36481 gctgtggatg cgaccgagca aggtttgtca tcaagtgagg cggaaaagcg ccttgccgaa
    36541 tttgggcaca atgaactcga agaaggcgag aaacgatcaa tcttggtcaa attcatcgag
    36601 caatttaagg atttgatgat tatcatccta gttgcggcag caatcttgtc agtcgtgact
    36661 tctggtgggg aagatatcgc agatgccatt atcatcctag ctgtggttat catcaacgct
    36721 gcctttggtg tttaccaaga aggaaaagct gaagaagcta ttgaagccct caaatccatg
    36781 tctagtccag ttgcccgcgt tcttcgtgat ggacacatgg cagagattga ctctaaagaa
    36841 ttggtaccag gcgatatcgt tgcccttgaa gcaggtgacg tggtaccagc ggacctacgt
    36901 ttgatagaag ccaactctct taaaattgaa gaagcagcct tgacaggtga atctgtacca
    36961 gtcgaaaaag acttgtcagt cgagcttgcg acagatgctg gtattggtga ccgtgtcaac
    37021 atggccttcc aaaactcaaa cgtaacctat ggtcgtggga tgggtgttgt tgtcaataca
    37081 ggtatgtaca ctgaagttgg tcatattgct ggtatgcttc aagatgcgga tgagactgat
    37141 acaccactca aacaaaattt gaacaacctt tctaaggtct tgacctatgc tatcttggtc
    37201 attgcccttg ttacttttgt agtgggtgtc ttcattcaag ggaaaaatcc acttggtgag
    37261 ttgttgactt ctgttgccct tgccgttgca gccattccag aaggacttcc tgctatcgtt
    37321 accatcgttc tttctcttgg tactcaagtt ttggccaaac gacattccat cgttcgtaag
    37381 ttgccagcag ttgaaacact tggttcaact gaaatcatcg cttctgataa gactggtacg
    37441 ctgactatga acaagatgac agtcgaaaaa gtcttctacg atgcggttct acatgactca
    37501 gctgatgata ttgaactagg tcttgaaatg ccactacttc gttcagttat cttggccaat
    37561 gatacgaaaa tcgatgtgga aggtaacttg attggtgacc caaccgaaac agcctttatc
    37621 caatatgcct tggacaaggg ctatgatgtc aaaggtttct tagagaaata tcctcgtgta
    37681 gctgaattgc catttgactc tgaccgtaag ctcatgtcaa cagttcaccc attgccagat
    37741 ggtcgtttcc ttgtagcagt caagggtgcg ccagaccaac tcttaaaacg ttgtcttctt
    37801 cgtgataagg ctggggatat tgctccgatt gatgagaagg ttacaaatct cattcataca
    37861 aacaattctg aaatggctca tcaagccttg cgtgtccttg caggtgctta taagattatc
    37921 gatagtattc cagaaaatct cacttctgaa gagcttgaaa atgatttaat ttttactggt
    37981 ttgattggga tgattgatcc tgaacgtcct gaagctgctg aggctgttcg tgtggctaag
    38041 gaagctggaa ttcgtccaat tatgattaca ggtgaccacc aagacaccgc agaagctatt
    38101 gccaaacgtt tgggaatcat tgacgcaaac gatacagaag accacgtttt aactggtgct
    38161 gagctcaacg aattatctga tgaagacttt gaaaaagttg ttggtcaata ctctgtttat
    38221 gcccgtgtgt ctccagagca caaggttcgt atcgtcaagg cttggcaaaa acaaggtaag
    38281 gtcgttgcca tgacaggtga cggtgtcaat gatgccccag ctctgaaaac agcagacatc
    38341 ggtatcggta tgggaatcac tggtacagag gtttctaagg gggcttctga tatgattctt
    38401 gcagatgata actttgcgac tattatcgtc gcagtggaag aaggacgtaa ggtcttctca
    38461 aatattcaaa agactattca gtacctactt tctgccaata ctgctgaagt attaaccatc
    38521 ttcctatcaa ccttgtttgg ttgggacgtc ttgcagccag ttcatctttt gtggattaac
    38581 ttggtaacgg ataccttccc agcaattgca ctaggtgttg aacctgcgga acctggtgtc
    38641 atgaatcata aaccacgtgg acgcaaggca agcttcttct caggtggtgt tttgagttct
    38701 atcatttatc aaggtgtact ccaagcagct cttgttatga gtgtttatgg ccttgcgatt
    38761 gcttacccag ttcatgtggg tgacaatcat gctattcatg cagatgccct aacgatggcc
    38821 tttgcaaccc ttggtttgat tcagctcttc catgcctaca atgtcaagtc tgtctaccaa
    38881 tccatcttga cagttggccc attcaagtct aagaccttta actggtccat cttggtatcc
    38941 tttatccttc tcatggcaac aatcgttgta gaaccgcttg aaggaatctt ccacgtaacc
    39001 aaactagact tgtcacaatg gggaattgtt atggctggaa gcttctcaat gattatcatc
    39061 gtcgaaatcg ttaagtttat tcaacgcaaa ctcggttttg acaagaatgc gatttaaggg
    39121 aggtttcgga tgtcagcata tcaattaccg accgtatggc aggatgaagc tagtaatcaa
    39181 ggagctttta cggggttaaa cagaccaaca gcaggtgccc gtttcgaaca aaacttgcca
    39241 aaaggagaac aagcttttca gctttattca ctgggaacac caaatggtgt gaaggttact
    39301 atcttattgg aagaattact agaagctggt tttaaggaag cggcttacga cttgtataag
    39361 attgctatca tggatgggga tcaattcggc tcagactttg tgaagctcaa tccaaattcc
    39421 aagattccag ccttattgga ccagtcaggt actgaaaacg taagagtctt tgagtctgct
    39481 catattcttc tttaccttgc tgagaaattt ggagcctttt taccaagtaa tcctgtggaa
    39541 aaggtagaag ttttgaattg gctattctgg caagcaggtg cagcaccttt tctaggtggg
    39601 ggatttggac atttcttcaa ttatgctcct gaaaaattgg aatatcctat taaccgtttt
    39661 acgatggaag tgaaacgcca gttggattta ttggataagg aattggctca gaaaccttat
    39721 attgcaggca atgactatac gattgcagat attgctatct ggtcttggta tggacagtta
    39781 gttcaaggaa atctttacca aggttctgca aaatttttgg atgcctcaag ttatcaaaat
    39841 ctagtaaaat gggcagaaaa aattgccaat cgtccagctg ttaagcgtgg attggaagta
    39901 acttatacag aaattaaata gcaaaaaagt catcttcgga tggctttttg ctacagttga
    39961 gggaaagggt ttgcagttat cggcttttgt gctataattg ctataatata gtaaaaagca
    40021 agaggagtgt gaggaagtgg aaaagaaaat tgtgaaggat atcttatttt tatctcaagt
    40081 gtctcagccg gcaagtcagg aggaccttta tcttgccaga gatttgcagg atacactctt
    40141 agcaaatcgt gatacctgtg ttggtctagc tgccaatatg attggggtgc agaagcgcgt
    40201 gattatcttt aatcttggct tggttcccgt ggtcatgttt aacccagtgc ttctgtcctt
    40261 tgaaggatct tatgaggcag aagaaggctg tttgtccttg gtaggtgtga gatcaactaa
    40321 gcgttatgaa accataaggc ttgcctatcg tgacagcaag tggcaggaac agaccattac
    40381 cttgacaggc ttcccagctc agatttgcca gcatgagctg gatcacttgg aaggacgaat
    40441 catttaggag gaaagcaaat gaaacgaata gtctttgaac ttatttttat cgcaacgacc
    40501 tggtatatct ttttaccgcc ccttaacctg accagctggg aatttctctt cttcctctgt
    40561 gggcatttgt tagttgtggc aatcttattt ggctttggca aggggataaa ccttgtcaaa
    40621 acggttcatg tgcgccacgg taaggcggaa gctgccttaa atcttgaggg tttcaaaatc
    40681 aatcggttag ggaaaattct gttagcttcg attggaggaa ttcttctctt ggcagctttg
    40741 gtttccttgg taacttccag catgtttcag gctaaaaatt atgccaatgt agtcacggtt
    40801 acggaaaaag actttactga atttcctagg agtgacacca gtaaggttcc tatcctagat
    40861 agaagtactg ctgaaaaaat tggagaccgc tacttgggtt ccctaaccga taaggtgtcg
    40921 caatacgtag cggcagatac ctatacccaa ttgacaattg atgggaaacc ttatcgggtc
    40981 acaccactag aatatgcaga ccctatcaaa tggtttaaca atcaagccaa gggaatcggt
    41041 gagtatatca aggtggacat ggtaactgga aatgcggatt tggtggactt gaagacacca
    41101 atcaagtatt cagactcgga gtattttaac cgtgatgtca aacgtcacct gcgcttgaag
    41161 tacccgacta aaatctttaa aactccatct tttgaggtgg acgatgaggg caatcctttc
    41221 tatgtagcaa cggtttacca aaagcaattt ggacttgcgg ttcctcgtcc tgcttcagtc
    41281 attatcttgg atgctacaaa tggagaaacc aaggaataca gcttatcaga tgttccagaa
    41341 tgggtggaca gggtctatcc agcagaggaa accattgagc aaatcaacta caacggcaag
    41401 tacaaggacg gtttcttgaa tgccatgatt tccaagaaaa atgtgaccca gactaccaag
    41461 ggctataatt acttgtctat cggtaatgac atctatctct acacaggtgt gacgtcggct
    41521 aatgcggatg agagtaatct tggtttcatc cttgaaaata tgcgaacagg agaaatcact
    41581 aagtatagct tggcttctgc gacagaagaa tcagcccgtg aatcagcaga aggtgctgtt
    41641 caggagaaat cctacaaagc aaccttccca atcctcatca acctcaatga caagcctctc
    41701 tacatcatgg gcttaaagga caatgctggc ttggtcaaag agtacgccct ggtagacgca
    41761 gtcgagtacc aaaatgttat cgttgctact acagtggaag agatgctcag caagtatgcc
    41821 aataaaaacg accttgaaat tgacaatgca acgacagaaa gcatcaaggg agtagtagca
    41881 gacctcaaat cagctgttat caagggagac actgtctact tctttaaagt tgatggcaag
    41941 atatacaagg tcaaggcttc agtatccgat gaccttcctt accttgaaaa tggtaaaacc
    42001 ttcgaaggtc aagtaggaaa agacaattat ctcaagacct ttaaagtaca ataatactct
    42061 tcgaaaatct ctagctctat ct
//
LOCUS       DBERDS010000014        42012 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.014, whole genome shotgun sequence.
ACCESSION   DBERDS010000014 DBERDS010000000
VERSION     DBERDS010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.014"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..606
                     /locus_tag="ACL73E_000855"
                     /pseudo
     CDS             1..606
                     /locus_tag="ACL73E_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            603..821
                     /locus_tag="ACL73E_000856"
     CDS             603..821
                     /locus_tag="ACL73E_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800853.1"
                     /translation="MSISPRFEALEQAIAFKDLEKVREAFKKMNSTWTINESVVRYNS
                     IAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(878..1120)
                     /locus_tag="ACL73E_000857"
     CDS             complement(878..1120)
                     /locus_tag="ACL73E_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGS0800854.1"
                     /translation="MKKDIHPEYRSVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(1216..2151)
                     /locus_tag="ACL73E_000858"
     CDS             complement(1216..2151)
                     /locus_tag="ACL73E_000858"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGS0800855.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            2255..2698
                     /locus_tag="ACL73E_000859"
     CDS             2255..2698
                     /locus_tag="ACL73E_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGS0800856.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            2814..3080
                     /locus_tag="ACL73E_000860"
     CDS             2814..3080
                     /locus_tag="ACL73E_000860"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGS0800857.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3077..3451
                     /gene="crcB"
                     /locus_tag="ACL73E_000861"
     CDS             3077..3451
                     /gene="crcB"
                     /locus_tag="ACL73E_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS0800858.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3445..3774
                     /gene="crcB"
                     /locus_tag="ACL73E_000862"
     CDS             3445..3774
                     /gene="crcB"
                     /locus_tag="ACL73E_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGS0800859.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3893..4240
                     /gene="rplS"
                     /locus_tag="ACL73E_000863"
     CDS             3893..4240
                     /gene="rplS"
                     /locus_tag="ACL73E_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGS0800860.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            4282..4353
                     /locus_tag="ACL73E_000864"
     tRNA            4282..4353
                     /locus_tag="ACL73E_000864"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4315..4317,aa:Arg,seq:cct)
     gene            complement(4408..5214)
                     /gene="yidA"
                     /locus_tag="ACL73E_000865"
     CDS             complement(4408..5214)
                     /gene="yidA"
                     /locus_tag="ACL73E_000865"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGS0800861.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(5227..6531)
                     /locus_tag="ACL73E_000866"
     CDS             complement(5227..6531)
                     /locus_tag="ACL73E_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGS0800862.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            6603..6980
                     /locus_tag="ACL73E_000867"
     CDS             6603..6980
                     /locus_tag="ACL73E_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGS0800863.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7071..7403
                     /locus_tag="ACL73E_000868"
     CDS             7071..7403
                     /locus_tag="ACL73E_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGS0800864.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            7415..8986
                     /gene="ffh"
                     /locus_tag="ACL73E_000869"
     CDS             7415..8986
                     /gene="ffh"
                     /locus_tag="ACL73E_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGS0800865.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKMDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(9181..10464)
                     /locus_tag="ACL73E_000870"
     CDS             complement(9181..10464)
                     /locus_tag="ACL73E_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGS0800866.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKKRVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(10718..11431)
                     /gene="rsmG"
                     /locus_tag="ACL73E_000871"
     CDS             complement(10718..11431)
                     /gene="rsmG"
                     /locus_tag="ACL73E_000871"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGS0800867.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            11525..12085
                     /locus_tag="ACL73E_000872"
     CDS             11525..12085
                     /locus_tag="ACL73E_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGS0800868.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            12087..12986
                     /gene="htpX"
                     /locus_tag="ACL73E_000873"
     CDS             12087..12986
                     /gene="htpX"
                     /locus_tag="ACL73E_000873"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGS0800869.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(13135..14694)
                     /locus_tag="ACL73E_000874"
     CDS             complement(13135..14694)
                     /locus_tag="ACL73E_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0800870.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQSVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(14933..15249)
                     /locus_tag="ACL73E_000875"
                     /pseudo
     CDS             complement(14933..15249)
                     /locus_tag="ACL73E_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            15419..15961
                     /locus_tag="ACL73E_000876"
     CDS             15419..15961
                     /locus_tag="ACL73E_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGS0800871.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            15961..16590
                     /gene="nth"
                     /locus_tag="ACL73E_000877"
     CDS             15961..16590
                     /gene="nth"
                     /locus_tag="ACL73E_000877"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGS0800872.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            16801..17322
                     /gene="pyrR"
                     /locus_tag="ACL73E_000878"
     CDS             16801..17322
                     /gene="pyrR"
                     /locus_tag="ACL73E_000878"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGS0800873.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            17341..18264
                     /locus_tag="ACL73E_000879"
     CDS             17341..18264
                     /locus_tag="ACL73E_000879"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGS0800874.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            18314..19393
                     /locus_tag="ACL73E_000880"
     CDS             18314..19393
                     /locus_tag="ACL73E_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGS0800875.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            19706..22882
                     /gene="carB"
                     /locus_tag="ACL73E_000881"
     CDS             19706..22882
                     /gene="carB"
                     /locus_tag="ACL73E_000881"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGS0800876.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLSSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23158..23967)
                     /locus_tag="ACL73E_000882"
     CDS             complement(23158..23967)
                     /locus_tag="ACL73E_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0800877.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(23969..24772)
                     /locus_tag="ACL73E_000883"
     CDS             complement(23969..24772)
                     /locus_tag="ACL73E_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0800878.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLTFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(24782..26269)
                     /gene="tacF"
                     /locus_tag="ACL73E_000884"
     CDS             complement(24782..26269)
                     /gene="tacF"
                     /locus_tag="ACL73E_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGS0800879.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            26605..27312
                     /locus_tag="ACL73E_000885"
     CDS             26605..27312
                     /locus_tag="ACL73E_000885"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGS0800880.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            27317..28339
                     /locus_tag="ACL73E_000886"
     CDS             27317..28339
                     /locus_tag="ACL73E_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGS0800881.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            28356..29225
                     /gene="licA"
                     /locus_tag="ACL73E_000887"
     CDS             28356..29225
                     /gene="licA"
                     /locus_tag="ACL73E_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGS0800882.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            29215..30093
                     /locus_tag="ACL73E_000888"
     CDS             29215..30093
                     /locus_tag="ACL73E_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0800883.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30105..30794
                     /locus_tag="ACL73E_000889"
     CDS             30105..30794
                     /locus_tag="ACL73E_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGS0800884.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            30880..31728
                     /gene="dprA"
                     /locus_tag="ACL73E_000890"
     CDS             30880..31728
                     /gene="dprA"
                     /locus_tag="ACL73E_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGS0800885.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            32618..33661
                     /locus_tag="ACL73E_000891"
     CDS             32618..33661
                     /locus_tag="ACL73E_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGS0800886.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            33828..35915
                     /gene="topA"
                     /locus_tag="ACL73E_000892"
     CDS             33828..35915
                     /gene="topA"
                     /locus_tag="ACL73E_000892"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGS0800887.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36136..36495
                     /locus_tag="ACL73E_000893"
     CDS             36136..36495
                     /locus_tag="ACL73E_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGS0800888.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            36588..37220
                     /locus_tag="ACL73E_000894"
     CDS             36588..37220
                     /locus_tag="ACL73E_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGS0800889.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            37264..37920
                     /locus_tag="ACL73E_000895"
     CDS             37264..37920
                     /locus_tag="ACL73E_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGS0800890.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            37990..39033
                     /locus_tag="ACL73E_000896"
                     /pseudo
     CDS             37990..39033
                     /locus_tag="ACL73E_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            39045..40082
                     /gene="leuB"
                     /locus_tag="ACL73E_000897"
                     /pseudo
     CDS             39045..40082
                     /gene="leuB"
                     /locus_tag="ACL73E_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40079..40348
                     /locus_tag="ACL73E_000898"
     CDS             40079..40348
                     /locus_tag="ACL73E_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGS0800891.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            40352..40711
                     /gene="leuD"
                     /locus_tag="ACL73E_000899"
     CDS             40352..40711
                     /gene="leuD"
                     /locus_tag="ACL73E_000899"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGS0800892.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            40873..41495
                     /locus_tag="ACL73E_000900"
                     /pseudo
     CDS             40873..41495
                     /locus_tag="ACL73E_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            41659..>42012
                     /locus_tag="ACL73E_000901"
     CDS             41659..>42012
                     /locus_tag="ACL73E_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800893.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRF"
BASE COUNT        12652 a         7626 c         9177 g        12557 t
ORIGIN      
        1 acgctcaaac cattgtcgca tctaaaaata aaatctcaat tcaagaagac aagaaagcgc
       61 tttaaaacca gtagacgttt tcataaggtt cgcttgatgt accaagatga agctggtttc
      121 ggtagaatca gtaaactggg atcttgttgg tctccaatag gagtaggtcc acatgtccat
      181 agtcactata tacgagaatt tcgctattgt tatggagctg ttgatgccca tacaggcgaa
      241 tcatttttct taatagctgg tagatgtaat actgagtgga tgaacgcctt tttagaagag
      301 ctttcacaag cttatccaga tgattatttt ttactcgtta tggacaatgc tatatggcat
      361 aaatcaagta tcttaaagat tccgactaat attggttttg catttattcc tccatacaca
      421 ccagagatga accccattga acaagtgtgg aaagagattc gtaaacgtgg atttaagaat
      481 aaggcctttc gaactttgga agatgtcatg aatcaacttc aagatgtcat acaaggactg
      541 gagaaggagg tgataaagtc catcgttaat cggagatgga ctagaatgct ttttgaaagc
      601 agatgagtat aagtcctcgt tttgaagcct tggaacaggc tattgccttc aaagatttgg
      661 aaaaagtccg agaagctttt aagaaaatga attccacttg gaccatcaat gaaagtgtgg
      721 ttcgttacaa tagtatagct cattatggac gtgttgaaac agctatttcc ttcctgccta
      781 gtagcatgga aaccgaacct acagatgagt ctggaacatg aaaacagcag ttgatttcaa
      841 gaaacaaaaa agaacagccg aaactgttct cttatcatta tttgagaccg tattttttgt
      901 tgaaacgatc cacgcgtcca tctgcttgag tgaacttttg acgtccagtg tagaatgggt
      961 gtgagtctga tgaaatttcc acacggatca atgggtaagt ttcgccttcg aactcaactg
     1021 tttcgttaga gcgttttgtt gaaccgctaa ggaattggta accagtagtt gtgtccatga
     1081 agacaactga gcgatattct ggatggatat cttttttcat tttgcaatat ttcctttctg
     1141 ccatggtctc tttgcgagcc atagattgtt accatactag tctatcagat tctgaaaagt
     1201 ttggcaagta ttttatcagt ttttaagcaa gttttttaac ttttggtaga tgatttcgtt
     1261 ttcttctagg ctataggaat tagcaccact tgctagaggg tggcctccac catcatgctc
     1321 cttggcgatt tcattgatag gatggatttt actgcgtaag cgaacgcggt agtggccatc
     1381 agcctgttcg acaaaaattc cccagagact cactctgtca atgcgtccag gtgcaccgac
     1441 aatggctgca gtttcagcat cggttacatt gtattgtttc aagacttctt gactcaggat
     1501 aacgcgagca gcaccatttt catccacttc cagatggtcg tagatgtagc cttgcagttt
     1561 agcaattttg tagctcatag tgtccatttt gcgagtgaga gccgcaaagt caaagttatg
     1621 ttctctcaaa taagcagcca ggcgaagagt ccgtgcagtg gtagaagggt agaggaagcg
     1681 acctgtatca ccgacaattc ctgcaaagag caactcagca tcgcgatctg ccaaggctag
     1741 ttgggttgtt tgggcaaata gggtgatcat ctcgctagcg ctacttgaac tagtatcgac
     1801 ccaagacagg tcaccgtata catcatcatt tggatggtgg tcaatcttaa tgagaaaatc
     1861 accttgacta tagcgcttat catcgatacg agcagtatta gctgtatcac agacgatgac
     1921 aagtgcgcct tggtaggctc tatcttcaac aagatccatc tcagccatcc aagtaagagt
     1981 tggttcatca aaaccgacgg ctttgatggt tttttctggg aaatgatgtt ccagcaaggc
     2041 tttcaatccc acctgacttc ctaaggcatc agggtctggt ttcatatgac gatgaatgat
     2101 aatggtgtcg tattctttaa ttttttctaa aatttgttgg caaatctcca taaataacct
     2161 caattctttc tcatttcatt gtagcacaag aatttttatt tttaaaatga aaaagatgtg
     2221 atataatgga gaaagataaa ttgaggagga cgatatggca ttagcaaaaa ttgtatttgc
     2281 cagtatgacc ggtaataccg aagaaattgc agatattgta gcagacaaat tacgtgactt
     2341 gggcttggat gttgatgttg atgaatgtac aactgttgac gcttcagact tcttggaagc
     2401 agacatcgct atcgttgcga cctatactta tggtgatggt gaattgccag atgagatgat
     2461 ggacttctac gaagacctag cagatctcaa cttgaatggc aaaatctacg gagtggtcgg
     2521 ctcaggagat accttctacg atgaattctg taaggctgtt gatgactttg accgtgtctt
     2581 tgtgtcaaca ggagcagaaa aaggttcaga gtgtgttaaa gttgatcttt ctgccgagga
     2641 agaagatatt gaacgcttgg aacaattcgc agaagaattg gttgctaaag taggataagc
     2701 ataaaagtgc gctgatgtaa tcaatcagtg catttttctt atcgagagtt gggattttac
     2761 tagcctaatt gatggctttt tgatacaata attcaaataa aggaggagac tgtgtggatt
     2821 tagatattat tcgtcaagaa atcgatcaaa tcgacgacca aattgtcaaa ctgttagaag
     2881 aacgaatgca cttagttgaa ggagttgtcg cttataagaa ggcttcaggg aaaccgattt
     2941 tagatactaa gagagaagca gttatttttg aaaaggttag aagtcgtgta gaggacaagc
     3001 gctatcagga gactattgtc gcgacttttt cggacatact caaacgttcg cgtgattatc
     3061 aggatcaaaa tatcaaatga aaaaagaaca attttatccg ctagggattt ttctagctgc
     3121 tatgttgggc ggacttgtcc gctacctagt ttccacttgg ttaccagcca gtccagattt
     3181 cccttggggc actctctttg tcaactatct gggaattttc tgcttgattt atcttgtcaa
     3241 gggctatctg gtctataagg ggactagtaa gggcttgatt ttagcactgg ggacgggttt
     3301 ttgcggaggt ttaacaactt tttccagcct aatgcttgat actgtgaagc tgcttgatac
     3361 agggcgttat cttagtttga tactgtattt gcttttgagt atcggtggag gcctgctttt
     3421 agcttactat ttggggagga agaaatggta atcgtctatc ttgcaatcgc ctgtggcttg
     3481 ggagcactcg tacggtattt cttttctcgc tataatcaag cttctaaatt gccactcgga
     3541 acgctcatag ctaatctttt aggttgtttt ttaattggag tattctacaa tcatgtagag
     3601 tctaaggaag tatatgctat tctagcaaca ggattttgtg gcggtttaac aactttttcg
     3661 accttgaatg acgaacttca aagactgcta agtgataaga aggtctttta ttcttacctg
     3721 actttgactt acataggtgg tttggttgcg atttttttag gaattttgct ataaatttct
     3781 ttactttttt gtgaaaattt ggtaaactgt atcttgtgtg taatggacgc acaagaatac
     3841 agtttatccg ctgaggaagt ttcctcaaga ttgacaaaga taggagaata aaatgaatcc
     3901 attaatccaa agcttgactg aaggtcaact tcgtacagat atcccatcat tccgtcctgg
     3961 tgacactgtt cgtgtacacg cgaaagttgt cgaaggtaac cgtgaacgta tccagatttt
     4021 tgaaggtgtt gttatcgcac gtaaaggtgc tggaatctca gaaaactaca cagttcgtaa
     4081 aatctctaac ggtgtaggtg ttgagcgtat cttcccaatc cacactccac gtgttgaaaa
     4141 aatcgaagtt gttcgttacg gtaaagtacg tcgtgcgaaa ttgtactact tgcgtgctct
     4201 tcaaggtaaa gcagctcgta tcaaagaaat ccgtcgttaa ttcgactaaa aaactctgct
     4261 tttcagcaga gtttttatct agctccctta gttcaatgga tataacaact ccctcctaag
     4321 gagtagttgc aggttcgatt cctgcagggg gcagtaatta gacatcaaaa accgctcagc
     4381 tgagcggttt ttatctattc tttcctttta cagtacccat gtacgaatag catgggcaac
     4441 gccggattcg tcatttgttt tggtgatgta tttggcgatt tttttgattt ctggatttcc
     4501 gttttccatg actacagggt tgccaacgac ttccagcatg gcacggtcat tttcttcgtc
     4561 tccgatagcc atggtttcat ctttggttaa tcctagtttt tcagctaagt gagtaatagc
     4621 tgaacccttg tctacattct ttttaaggag ttcgaggtag aaaggagcag atttgttgat
     4681 agagtagtgc tcgtaaaatt cggctggtat tttttcaatc gcagcatcga ggatttctgg
     4741 ttcatcgatg aacatacact tgacaatttc cttgccagcc atttcttcag gggtacggta
     4801 gaagataggc atgctgacga gggttgattc gtgtacagtg tattttccga tattgcgatt
     4861 tgcagtatag ataccgtcct tggtaatggc atgcatgtgg acaccgagct tgcgactgag
     4921 gaattccata tccagataat cctcataggt caaggattcg ctgataatct catggccagt
     4981 agcagtttct tggacaaggg caccattgaa ggtcaccaca tagtcacctt ggtctctcaa
     5041 ctgcaagtcg tccagaagtt tggcaacacc tgcgatgggg cggccagttg caatcacgac
     5101 tttgacacca gcttctttgg catcttggat ggcagaaaag acttcaggag tgatttcctt
     5161 ttggctgttg actagggttc cgtcaatatc gacggcgatt agtttaatac tcataaattt
     5221 cctcttttag tttttatttg gggtaaaatg atcgttctca atcaagtgta aaaattgctg
     5281 ggtgatgctt gcgaagatgc tgttttggtc taacatttct ttcgggaaat aaaagcgatt
     5341 atctccgtgg cgacttccag caagggattg gacgataggg gacaggctag agagttctgc
     5401 cagttctcca tttttttgta aaatctcaat ctgtgtcctt ggattttcag attcgggacg
     5461 gtaaatatca taagggaggt caaagttctt atgaatggca gtatagtagt cgggatcaaa
     5521 gccgatgtcc tcaaccaatt ttctcatgct agcgagttgg tcttggtctt cttgtgaaaa
     5581 ggtaatggat ttaaagacct tgcggttgac aaagcgatgc gataaatctg caagaatctt
     5641 gtcaggactg gtcatccaga gttggaagta ggtattcatc acaccatcat ccagagccag
     5701 atagtcagtc aaggtcacat ttttttcgaa gaaaggcagg aggtgtggag aagttcgggc
     5761 aaagaaatcc ttgtcctcag gatagagttc cttggcgcgt ttgagaagat tctgtaggag
     5821 aacttccatg gcgcgtgttg cggggtggaa ataaacctgc atgtacatct ggtagcgact
     5881 gaggacgtag tcttcgatgg cgtgcatgcc attgcgctga aaggcgatac cattttcgat
     5941 aggacgaatg actcggagga ttcgagtcag gtcaaattcc ccataggatg ctcctgtaaa
     6001 ataggagtcg cgcaagagat agtccatgcg atctgcgtca atctgactag aaatgagctg
     6061 cacgacctgc ttgttaggat aggtatggtc tatgacactg gcaactttct ctggaaaatc
     6121 gggcgctact tgtagcaaga cttggtgaat ctctgtctca ggattttgaa taatctcctg
     6181 agtaatggct tcatggtctg tatcaaagag attttcaaaa gtatgggagt aggcaccatg
     6241 cccaaggtcg tgtaggagag cagcggtcat ggtcaagaga gactcggcag gattccattc
     6301 ctcaggatat ttttcttcga aaatctctgt gatgcgtcgt gcaatttcat agactcctag
     6361 acagtgagag aagcgactgt gttctccacc gtggaaggta taactggaag ttcccagttg
     6421 tttgatccgg cgcaaacgct gaaattcttt tgtattaatc aagtcataga tgatttgatt
     6481 attgacatgg atgtagttgt gaacagggtc acggaatact ttttcgttca tatgaccatt
     6541 atagcaaaat cctgctcttt ttggtaaaat agtaggacaa gagacaagaa agagggcctg
     6601 atgtgaagat tcggatgcga aatacaattc agtttgatga gcagttggaa gtgattgacc
     6661 agctttatga tgtggaagtg catgaaaaag gagattatag ctacctgctt ttctataatg
     6721 aggaaaagga aaaagtagtg attaaatttc atggtcaaga acttatgatg agccgatttt
     6781 ctaatcccaa gaccattatg cgctttctaa aggatagcga tagtttagcc tatattccta
     6841 cacctatggg catgcaggag tttatcatcc aaacgagcca ttatcaagtt gataggcaaa
     6901 agattgaact agattatcaa ctacaaaatc aagagggaca tccttttgcc agctatcaat
     6961 tggaaattac ttggggctag gctcatgtct ttttcaaatt tagctatcta tcttcttgga
     7021 tcggcttcct agtgtggtag attaggctaa tttttggtat aataaaagtt atggaaatcg
     7081 aaaaaaccaa tcgtatgaat gcgctctttg aattttatgc ggcgcttttg acagataagc
     7141 aaatgaatta tatcgagctc tactacgctg atgattacag ccttgctgaa attgccgagg
     7201 agttcggtgt cagtcgtcag gctgtctatg acaatatcaa gcgaacagaa aagattctgg
     7261 aagattatga gatgaaattg cacatgtact cggattatat tgtccgcagt cagatttttg
     7321 atcagatttt ggagcgctat cccaaggata actttctgca ggagcagata gaaattttaa
     7381 caagcattga taatagagaa taagaggaag aaaaatggca tttgaaagtt taacagaacg
     7441 tttgcagaac gtctttaaaa atctacgtaa aaaaggaaaa atctctgaat ctgatgtcca
     7501 agaggcaacc aaagagattc gcttggcctt gcttgaagcc gacgttgcct tgcctgttgt
     7561 gaaggatttt atcaagaagg ttcgtgagcg tgcagtcggg catgaggtca ttgatacact
     7621 taatcctgcg caacagatta ttaaaatcgt tgatgaggaa ctgacagccg ttttaggttc
     7681 tgatacggca gaaattatca agtcacctaa gattccaacc atcatcatga tggttggttt
     7741 acaaggggct ggtaaaacaa cctttgctgg taaattggcc aacaaactca agaaagaaga
     7801 aaatgctcgt cctttgatga ttgcggcgga tatttatcgt ccagctgcca ttgaccagct
     7861 taagaccttg ggacaacaga ttgatgtgcc tgtctttgca cttggaacag aagtaccagc
     7921 tgttgagatt gtacgtcaag gtttggagca agcccaaact aatcataacg actatgtctt
     7981 gattgatact gcgggtcgtt tgcagattga tgagctcctc atgaatgagc ttcgtgatgt
     8041 gaaagcattg gctcaaccaa atgaaatctt gcttgtcgtt gatgctatga ttggtcagga
     8101 agcagccaat gttgcgcgtg agtttaatgc tcagttggaa gtgactgggg tcatccttac
     8161 caagattgat ggcgatactc gtggtggtgc tgctctgtct gttcgtcaca ttactggaaa
     8221 accaatcaag ttcactggta caggtgaaaa gattacggac attgaaacct tccacccaga
     8281 ccgcatgtct agccgtatcc ttggtatggg ggatatgctc actttgattg agaaagcttc
     8341 tcaggaatac gatgaacaaa aagcccttga aatggctgag aagatgcgcg aaaacacctt
     8401 tgattttaat gatttcatcg atcaattaga tcaggtgcaa aatatggggc cgatggaaga
     8461 cttgctcaag atgattccag gtatggccaa caatccagcc cttcaaaaca tgaagatgga
     8521 tgaacgccag attgctcgta aacgtgccat tgtgtcttcg atgacacctg aagagcgtga
     8581 aaacccagat ttgttaaatc caagccgtcg ccgtcgtatt gctgctggtt ctggaaatac
     8641 attcgtcgaa gtcaataaat tcatcaagga ctttaaccag gctaaacagc tcatgcaggg
     8701 tgttatgtct ggggatatga ataaaatgat gaagcaaatg gggattaatc caaataacct
     8761 tcctaaaaat atgccaaata tgggaggaat ggatatgtct gcccttgaag gaatgatggg
     8821 acaaggcggt atgcctgact tatcagctct cggaggagca ggaatgccag atatgagcca
     8881 gatgtttggt ggcggtttga aaggtaaaat tggtgaattt gccatgaaac agtccatgaa
     8941 acgtatggct aacaaaatga agaaagcgaa gaagaaacgc aagtaagaca agagattgat
     9001 gcaaatctca tttgatgaga aaataaagta aaaatttcta tgataaaacg tacagtatca
     9061 aggttttaga atatctgata ttatacgttt tttgatttta ataattttgt taagacactt
     9121 ttattatggt atgcgaaaaa tccactcagc tgtctgagtg gattaggtgt atttagactc
     9181 ttagtcttta ttttcgtatg gcaagatcaa gttcaagatg attcctgtca tggctgaaag
     9241 ggcagtacct gaaagtgtaa ctggaccaag tttaaggata gctcctccaa gtccaagaac
     9301 caacatagca cttgcgatga tgaggtttcg catttgagcg aaatcaacac gttttttaat
     9361 caagactttc aaaccattgc tggcgataac cccatagaga aggattgaca taccaccaag
     9421 tacagcgttt ggaatagttg aaatcaaggc agtgaattta ccaaggaagc tgagggcaat
     9481 cgcgatgaag gcagcgttac ggataactga gacagaagcg atacgagtca taccgataac
     9541 ccctgtattt tctccgtaag ttgtattggc tggtccacca aggaaggcag aaacagaagt
     9601 tgcgataccg tcaccaagaa gagtacgatg aagacctggt tcttttaaga attgacggcc
     9661 acagatttga cccaaaacag tatggtctcc gatatgttca gaaattgtta cgatagcgat
     9721 tggcaagata gcgatggctt ctggaccaaa gtaaagattg tactctttaa aggcaccacc
     9781 tgtgctaaat ggcaagtaga aaccaggaat ttcgaaccag ttggctttaa gaactggtgt
     9841 aaagtcaacc aagccaagag ttagtgcgaa aaggtaacca ccgataatgg caaagaggaa
     9901 tggaatgatt cgtaggaagc cttttccttt tgtattgata aaggcagcaa ttaggaaagt
     9961 aacaacggct accagagcat ttttccaatt tccgtctgct acaagacctg cattggtaac
    10021 agctgaacct gcaagtccaa gaccgataac gatgatcata ggaccgataa tgattggtgg
    10081 caagagttta tcaatccatt ttgttcctac aaatcggatg ctggtagcaa caaggacata
    10141 gaccaaacca gtcaagataa cccctgtttg ggcagcagat acatcacccc ccatttcttt
    10201 catagccagt gacatagctg tgataaaggc aaatgaagaa cctagataaa ctggaacttt
    10261 aaaaccagta gcaatcatgt agatgagtgt tccaacacct gaagcaaaaa gggcaacaga
    10321 tacaggcatt cccaaaatca atggtaccaa gatggtcgca ccaaacatgg cgaaaacgtg
    10381 ttggaagcta aggagaattc cttttccatc cgaaggacgt tggtcaacgt ctagtaacaa
    10441 atcaacagtt gattcttgtt tcatataaac ctcacttttg ggcatcagaa aagagcccat
    10501 tattttacag caataggccc tcagagtaag acttctctaa aatctagact ttaaagagtt
    10561 tcaaatattt ttgcgtcttc gtcacctcac gggatgacat taaaaacctt tgcttaggat
    10621 agtatagcag aaaaaaatga ttttgtaaat cattttttcc cgagcctaga aataaaagag
    10681 cgaggctgat tttgtaaaca tttgtttact aaaaaattta aagtgggcgt ttatttggca
    10741 taccagcctt acgtggatat ttatttggtg tttctttttt cttttctacc actgtgatat
    10801 agcgcggatc tctattcggt agggcgtagc tgagattgtc ttcgacctta ctaaaaagga
    10861 gattgagggc attcttagct tctaataatt cctcaggcgc attgctggcc ttgagtgcca
    10921 atagtttgcc accaacctta aggtagggaa tagtcaattc agataggacc tgcatacggg
    10981 caaccgcacg agctgttaca aaatcatatt gagcacggaa gttcttgtct tgggcaaaat
    11041 cttcggcacg tccgtggtag aaatgaactc cgttcaaatc cagttcttga gccaagagtt
    11101 gtaggaagtt gatgcgctta ttgagtgaat caataatggt cacatctaac tccggataga
    11161 gaattttcat tggtagacta ggaaatcctg ccccagcccc gatatcaaga agtttgatag
    11221 tttcattggg aatcaaacct tgaagaatgg gtgcaatcga atcgtaaaaa tgtttgagat
    11281 aaacttcttc cttgtccgta atcgccgtca aattaatctt ctcattccac tcgaccaaga
    11341 gctcaaaata acgttcaaat tgttcttttt gctggtccga aagtggaaga ttctgctcgg
    11401 caagcaagtt gtaaaatgtt tttggtttca tagttatttc cttctttagt atcatcttat
    11461 tttaccacaa tcatagaaaa tttgatatac tggtactaat ctaaaagcag aaaggactta
    11521 tattatgact tggattattc ttggagtttt agctcttgtt gttatttttg tgattgttag
    11581 ctataacggt ttggttaaaa atcgtatgca aaccaaggag gcttggagtc agattgatgt
    11641 tcagttgaaa cgtcgaaatg acctcttgcc aaacttgatt gagactgtaa aaggttatgc
    11701 caaatatgaa ggttctaccc ttgaaaaggt ggcagaacta cgtaaccaag tggcggcagc
    11761 gacttcacca gcagaagcta tgaaagccag tgatgccctc actcgtcagg tttcaggtat
    11821 ttttgcagtt gcagaaagct atccagattt gaaagctagt gctaactttg ttaaattgca
    11881 agaggagttg acaaacacag aaaataaaat ttcttactct cgtcaactct ataacagtgt
    11941 tgtcagcaac tacaatgtaa aattagaaac tttcccgagc aatattatcg ctggaatgtt
    12001 tggatttaaa gcggcagatt tccttcaaac acctgaagag gaaaagtcgg ttcctaaagt
    12061 tgattttagc ggtttaggtg actaagatgt tgtttgatca aattgcaagc aataaacgaa
    12121 aaacctggat tttgttgctg gtatttttcc tactcttagc tcttgttggt tatgcggttg
    12181 gttatctctt tataagatct ggacttggtg gtttggttat cgcactgatt atcggcttta
    12241 tctacgcttt gtctatgatt tttcaatcga cagagattgt catgtccatg aatggagcgc
    12301 gtgaggtgga tgagcaaacg gcaccagacc tctaccatgt agtggaagat atggctctgg
    12361 tcgctcagat tcctatgccc cgtgttttca tcattgatga tccagcctta aatgcctttg
    12421 cgacaggttc taatcctcaa aatgcggctg ttgctgcgac ttcaggtcta ctagctatca
    12481 tgaatcgtga agaactagaa gctgttatgg gacatgaagt cagtcatatt cgtaattatg
    12541 atatccgtat ttcgactatt gcagttgccc ttgctagtgc tatcaccatg ctttctagta
    12601 tggcaggtcg tatgatgtgg tggggtggag caggtcgcag acgaagtgat gatgaccgag
    12661 atggaaatgg tcttgaaatc attatgctag tggtttccct actagctatt gtactggcac
    12721 ctctcgctgc aaccttggtt cagctcgcta tttctcgtca gagggaattt ctggcagatg
    12781 catctagtgt cgagctgact cgcaatcccc agggaatgat taatgcccta gataagttgg
    12841 acaatagcaa acctatgagt cgccacgtcg atgatgctag cagtgccctt tatatcaatg
    12901 atcccaagaa aggtgggggg ttccaaaaac tcttttatac ccacccacct atctcagaac
    12961 ggattgaacg tttaaaacat atgtaaaatg aaggctggaa aaaagtcttt aaaatctgaa
    13021 aaacgcataa tatcaggtgt gaaaacttga tattatgcgt tttactatgg gaagatttac
    13081 ttctttttct cctaaaattg tgtttttgcc ccacctatct gctatgttgc aaatttataa
    13141 atcttctaaa ttaactagct tcaaaccgtg ttctgtcatg cgatagatga tcgagcagac
    13201 ttcttttaag aaacgacggt catgcgaaac agtgatgaga ccgccaggat aagtggcaaa
    13261 gagttttctg atttggggtt gagaagtggg agaaaagttt cgtgtgggtt catccagcag
    13321 gagaaagttt ggtttgcgca ggactaaatc caaaagcagg agttttccct gttgtccgcc
    13381 agataaggag cgaatttgat gctgcatttc tggataactg aaattgagac tagctaggtg
    13441 agattggatt ttctgtagtt cctctttttc cccagtttta ctgagatagg ctattgggga
    13501 taaatccaat tgcagttttt tgtggtaatc ttgtggcata aaaccaagtg aaatctctct
    13561 tttatcattc agaagtctct gtaacttggc taacagagtt gatttcccaa caccatttgg
    13621 cccgataata ccgatttttt cttggccacg gacagttagt tgtagttttt gaaccaaaac
    13681 tcggtcgtca atggacaaat tttctttttc cagttggact aagactttag aagctggtaa
    13741 tggttggatg tctgaaaaga aaagttggat ttgttcctct tcaagtggct tttgagtcat
    13801 ggactgagct gccttttcgt agcgtttttc ttgtgagagg acagttttca tctttttagc
    13861 caataggcga ccggcagtac tatctttggt agctcgaagc gcagtttcta cactttgctt
    13921 gactctccga tgtttttcca tggttttatc gtaggctctt tggttgttag cagcttgctg
    13981 actttgtttg gcaaaattag cctttctctg ctcactatag ctatcatagt ctaaatgctc
    14041 tactagcgtt tccgcttctt tacggtgttt gaccagtcgc aagtgaacaa tagtgtctgc
    14101 cgtttcagaa agaaagtctt catcatggga aatgaaaata acggtttgcc tggtcttttg
    14161 aatctggcct tttagccaat caactgtctc aaggtctagg tcatttgaag gttcatctaa
    14221 aaatagaatc tcaaagggtt tggctaactc atggataagc tgaattttca aagcttcgcc
    14281 ccctgataga ttgccaatct tttggtcact tgcgaaacga ttgctatcaa aatgcaattc
    14341 ctccgccaaa cgatagagga tactgtagtc taaatcaata gaatctaaaa agaagtagtc
    14401 gtgtaaagtt ttctttttca gctcctcggg aagtttttga ggaatgtagg ccagtgactg
    14461 atagtcagat tggatgtttc ccttgatagt gaaatcagac aaagcttccc ccattaaaat
    14521 tttaagtaag gttgatttgc catttccttc ttcaccaata atagcaacct tttccccgtc
    14581 ttggatggtc atgcttaggt cagatacaag atctcgtaaa tctttgtttt gtgtgatggt
    14641 tagatgattg atttttatca tatgatttcc ctttctagaa tgttcatagt gcataacaaa
    14701 aagctctact ttacctagta gagcccaaag tctatgtcaa aaaaactcta ttaacatgcc
    14761 agaaaaagag cataaaagag cacacaaaaa gagacaaaaa caagatctac taaataaagg
    14821 ttctttattt gatagactta gttgttcatg tctcccttac ctccgagtat tagtatcttt
    14881 atattatacc tttaaggaaa ttttgtcaac agaaaactgg aaattctatg ctctaaaatc
    14941 caaaaacagg tccatagaga cttagtacgt gtttgacatg ctcgtaatgg aatttatcat
    15001 agtttcgcca agcagtgcgt gcttgatcgt ttagttttag gctacccagt ccaatcagaa
    15061 gactggtggg ttggtaaaat ttctcaagat caattaagat actgttgttc aacttttccg
    15121 ttttttgagc tcttgcatag tagtgtttag cagctcttgt agtcgaatat catctgccgt
    15181 accctgttta cagttttggt agcttttatt taacttggat aggagttgaa tgagtttctt
    15241 gtcttccatg tgagcatcct ccttgatctg atgtactctt tccctatagt atagcactaa
    15301 aaaacaaaac tgtcatagta aatatgttaa aattttgaat tttaattaca aagtttggtg
    15361 tgctgatttg tagccttttc atggtataat caagagagta aatctttatg gaggaagtat
    15421 gaaattaaat attcaagaaa ttcgtaagca gtctgaaggt ttgaactttg aacaaacgtt
    15481 agatttagtt gatgacctgc gtgcacgtaa tcaagaaatt ttagatgtaa aagatatcct
    15541 tgcagttggg aaagtacaat atgaagaccg tatgtatttc ttagattatc aactatctta
    15601 taccattgtt cttgcttcga gtcgcagtat ggagccagtt gagttagttg aatcttatcc
    15661 agtcacggaa gttttcatgg aaggcgcaac taaccatcta aatcaagaaa ttttagatga
    15721 tgacttggtc ttgcccatcg aaaatgaggc gcttgacctt gctgagagtg tatcagacaa
    15781 tatcttgcta aacattccta tcaaggtctt gacggctgaa gaagaagctg gtcaaggatt
    15841 tgtctcagga aatgactggc aaatcatgac agaggaagaa taccaagctc aacaagcagt
    15901 aaagaaagaa gaaaacagtc cttttgctgg cttacaagga ctatttgacg gagatgaata
    15961 atggtcttgt caaaaaaacg agcacgaaag gtgctagaag aaatcattgc cctcttccca
    16021 gatgccaagc ctagtcttga ttttaccaat cattttgaac tcctggttgc ggtcatgtta
    16081 tcagcccaga cgacagatgc agcggtaaat aaggccacac caggtctctt tgttgccttt
    16141 ccaacacccc aagctatgtc tgtagcgaca gagagtgaga ttgcttcaca tatttctcgc
    16201 ttgggattgt atcggaataa agctaaattc cttaaaaaat gtgcccaaca gttactagac
    16261 gattttgatg gtcaagtccc tcagacacgt gaagaattgg agagtttggc aggtgttggt
    16321 cgcaagacag ccaatgttgt catgagtgta ggatttggga ttccagcctt tgcagtggat
    16381 actcatgtgg agcgtatttg caaacaccac gatattgtca aaaaatcagc gacgccactt
    16441 gaggtggaaa agcgggtcat ggatatcttg ccgcctgagc agtggttagc tgcccatcag
    16501 gccatgattt attttggaag agccatttgc catccaaaaa atccagagtg tgaccagtac
    16561 ccacaattat atgattttag caatttgtaa gatgctacat tgaaactttt tgcttgattt
    16621 taagcatgct ttgtgctata gtaaatgata actaaatatt cctttaaacc tgtcccgtga
    16681 ggcaggcaag gagcgcgata aagtagaagg gtgaagtcta tactgtgtgc agtagggctc
    16741 gcttggctat aaatttcaag tctccttgtt taaggagact tttctttttg gaggtttgtc
    16801 atgaaaacaa aagaagttgt agacgaattg accgtcaaac gagcgattac gcgtattact
    16861 tatgagatta tcgaacgcaa caaagatttg aataagatcg tcttggctgg tattaaaact
    16921 cgtggtgtct ttattgccca ccgaatccaa gaacgtttga agcagttaga aaatctttca
    16981 gttcctgttg tggaattgga tactaaacct ttccgtgatg atgttaaaag tggagaagat
    17041 acttctttgg tttctgtcga tgtgacagac cgcgaagtta tcttggtgga tgatgtgctc
    17101 tatacaggtc gtaccatccg tgctgctatt gataatattg tcggtcatgg tcgtcctgcg
    17161 cgtgtgagtt tagcagttct agtcgatcgt ggacatagag aattgccaat ccgtccagat
    17221 tacgttggaa aaaatatccc aaccagtcgt tctgaagaaa tcatcgtaga gatgacagaa
    17281 cttgatgacc aagacagagt tctgattact gaagaagctt agaaagttaa aggagtagcc
    17341 atgtcagaaa atcaacaagc attgaaccat gtggtgtcca tggaagacct cactgtcgat
    17401 caagtaatga aattgatcaa gcgaggaatt gagtttaaaa atggagccca gcttccctat
    17461 gaagaccatc cgattgtttc caatctcttc tttgaggatt ctacacggac acataagtcc
    17521 tttgaagtcg cagagattaa acttggattg gaacgacttg actttgatgt gaagactagt
    17581 tcggttaata agggtgagac actttatgac accattttga ctctgtctgc tttaggagtg
    17641 gatgtctgtg tgattcgcca tccagaggtc gactactata gagaattgat tgctagtcca
    17701 acgattacga cttccatcat caatggtgga gatggttcgg gccaacaccc tagccagagc
    17761 ttgcttgatt tgatgaccat ttatgaggaa tttggccact ttgagggtct taaagttgct
    17821 attgcaggtg acttggacca ctcacgcgtt gccaaatcca atatgcagat tttgaaacgc
    17881 ttgggatctg aactcttttt cgctggacct gaggaatgga gaagtcaaga gtttgcagac
    17941 tatggacagt ttgtaaccat tgatgaaatc attgatcagg ttgatgtcat gatgtttctc
    18001 cgtgtgcaac acgaacgcca tgatagtgga gctgtatttt caaaagaaga ctaccatgcc
    18061 caacatggct tgactcaaga acgttacgat cgtttgaaag aaacagcaat cctcatgcac
    18121 ccagctccaa tcaatcgtga tgtagaaata gcagaccact tggttgaagc accaaaatca
    18181 cggattgtcc aacaaatgac caatggtgtc tttgttcgaa tggcaatctt agaatccgta
    18241 ctagcgagta gaaacgccaa ctaaaacaca agacgttaaa agacgccagt gagcgtccac
    18301 gagaggtgaa aatatgacaa aaagaattct agtattagaa gatggcacag tttttgaagg
    18361 caaggccttc ggagcagata ttgatgtaac aggcgaaatc gtctttaata cagggatgac
    18421 cggctaccaa gaatccatta cagaccagtc ttataatgga caaatcttga cctttactta
    18481 tcctttggta ggaaattatg gtattaatcg tgatgattat gaatccatta ttccaacttg
    18541 taagggagtc gttgtttttg aagaagcgcg tagagctagc aactggcgca accaaatgac
    18601 cttggatgaa tttttgaaag ccaagaaaat tccagggatt tcaggaattg atacgcgtgc
    18661 tcttaccaag attatccgta agcatggtac tatgcgtgca accttgaccc atgttgggga
    18721 cagtatggac catgtgacgg accagctcca agcaacagtt ttaccgacag acaatatcaa
    18781 acaggtttct actaaaacgt cttatccagc tccaggagtt ggtttgagcg tggtgctagt
    18841 ggactttggt ctcaagcact caatcctacg tgaactttct aaacgcaact gtaacgtgac
    18901 agttgttcct tattcgacaa cggctgaaga aattctccat ctcaatcctg acggagttat
    18961 gttgtcaaat ggtccaggta acccagaaga cgttccacaa gcactcgaca tgattcgcgg
    19021 tgtacaagga aaaattccaa tctttggtat ttgtatggga caccaactct ttgcaatggc
    19081 aaacggggct aagacctata agatgaagtt tggccaccgt ggattcaacc atgcggtacg
    19141 tgaaatcgca acaggacgag tagacttcac cagccagaac catggttatg cagtcagccg
    19201 cgaggatttg ccagagcact tgattattac ccacgaagaa atcaatgaca agtcagtgga
    19261 aggtgtgcgc cacagatacc aacctgcttt ctctgttcaa taccacccag atgcagctcc
    19321 tgggccacac gacgctagct acctatttga cgagtttatc gagatgatgg aagtttttaa
    19381 acaatcaaac taagaacgag taaaagctcg tcggagaatt tatgtaactg aacacggacg
    19441 gaaagctcag aatgtagaga aaccaacttg gattgtcaat ccttccttga tttcctaaaa
    19501 ttcaatcgct ttctattcgt cctttgtatc ttatttaatg tcgccctgag aggcgacgaa
    19561 tagaaaggag aagggtgctc cgtatttgct gaactgaata cgggctacgg acggtgctaa
    19621 aaagatagtt attcctagaa ctgacagttc ttcgtcataa ctcctatttt agctttgtcc
    19681 gcttgacacc cttaatatct tatatatgcc taaacgtact gatattcaaa aaattatggt
    19741 gattggttct ggtccgatta ttattggtca ggctgctgag tttgactacg ctgggactca
    19801 ggcttgcttg tcgttgaaag aggaaggtta tgaggttgtt ttggttaact caaatcctgc
    19861 aaccatcatg acggacaagg aaattgctga caaggtttac attgaaccga ttacacttga
    19921 gtttgtgaca cgtattcttc gtaaggaagg tccagatgcc ttgctaccaa cactcggtgg
    19981 tcagacaggt ctcaacatgg ccatggaatt atctaaaaat ggtatcctag acgagcttgg
    20041 cgttgaactt ctgggtacca aattatctgc cattgaccaa gcggaggacc gtgacctctt
    20101 taaacaattg atggaagagc ttgaacaacc cattccagaa tctgaaattg ttaacacagt
    20161 agaagaagca gttgcctttg cagcgacaat tggctaccca gtcatcgttc gtccagcctt
    20221 tacccttggt ggtactggtg gtggtatgtg tgccaacgag aaagaattgc gtgaaatcac
    20281 tgaaaatggt ttgaaattgt cacctgttac ccaatgtttg attgagcgtt cgattgccgg
    20341 tttcaaggaa attgaatacg aagtgatgcg tgactcagct gacaatgcct tggttgtttg
    20401 taacatggaa aactttgacc cagttgggat tcacacaggg gattccattg tatttgcccc
    20461 tgcgcaaacc atgtcagact atgaaaacca aatgcttcgt gatgcgagct tgagcattat
    20521 tcgtgccctc aagattgaag gtggatgtaa tgttcagcta gctcttgatc ctaacagctt
    20581 caagtattat gttatcgaag taaaccctcg tgtatcacgt tcgtcagccc ttgcttctaa
    20641 agcgacagga tatccgattg ctaagttggc tgccaagatt gcagtaggtt tgaccttgga
    20701 tgaggttata aacccagtta caggttcaac ctatgccatg tttgaaccag cccttgacta
    20761 cgtagttgct aagattccac gtttcccatt tgacaagttt gaaaagggtg aacgccgtct
    20821 cggtacacaa atgaaggcga ctggagaagt catggcaatc ggtcgtaaca tcgaggaatc
    20881 tcttctcaag gcctgccgct cccttgaaat tggggtgcac cacaatgaaa tacctgaact
    20941 tgcagcagtt tctgatgatg ccttgattga aaaggttgtc aaagcccaag atgaccgtct
    21001 cttctacgta tcagaagcca ttcgtcgtgg ctacacacct gaagaaattg cagagcttac
    21061 aaaaattgat atcttctatc ttgataaact cttgcatatc tttgaaattg agcaagaatt
    21121 gggtgctcat ccacaagatt tagaagtttt gaaaacagcc aaacttaatg gtttttcaga
    21181 ccgtaagatt gctgaactct ggggaacgac tgatgataaa gttcgccaac ttcgcttgga
    21241 aaacaagatt gttccagttt ataagatggt agacacttgt gcggcagagt tcgactccga
    21301 aacgccatat ttctattcaa cctatggttg ggaaaatgaa tctatcagat ctgataaaga
    21361 atctgtactt gtcctaggtt caggtccaat ccgtatcggt caaggggttg agtttgacta
    21421 cgcaaccgtt cactctgtta aggctatcca ggcagctggt tatgaagcta tcatcatgaa
    21481 ctcaaaccca gagaccgttt caacagactt ctctgtatca gataagcttt actttgagcc
    21541 attgacattc gaagatgtta tgaacgtcat tgacttggaa caaccaaagg gagttatcgt
    21601 tcagttcggt ggtcaaacag ccatcaacct tgcggagcca ttggcaaaag caggtgtgac
    21661 catccttggt acacaggttg ctgacctaga tcgtgccgaa gaccgtgacc tcttcgagca
    21721 agctctcaaa gaattggata ttccacagcc accaggacaa acggctacca atgaagaaga
    21781 agcagctctt gcagctcgta agattggctt cccagttctt gtccgcccat cttatgtact
    21841 tggtggacgt gccatggaaa tcgttgaaaa cgaagaagac cttagttctt acatgcgaac
    21901 tgctgttaag gctagtccag accacccagt tcttgtcgac tcttatatcg ttgggcaaga
    21961 gtgcgaagtt gatgccattt cagatggtaa aaatgtactc attcctggta tcatggagca
    22021 tatcgaacgt gctggtgtcc actcaggtga ctcaatggct gtttacccac cacaaacctt
    22081 gtcgcaaaag gttcaggaga ccatcgcaga ctacaccaaa cgcttagcaa tcggtcttca
    22141 ctgccttgga atgatgaaca tccagtttgt tatcaaggat gaaaaagtct acgttattga
    22201 ggtcaatcca cgtgccagcc gtactgttcc attcctatct aaggtaacca atattcctat
    22261 ggctcaagta gcgaccaaac tcattcttgg tcaaagttta tcagaacttg gctaccaaaa
    22321 tggactttac cctgaaagca cccgtgttca tatcaaggca cctgtcttct cctttaccaa
    22381 actagctaag gtagacagct tgctcggtcc tgaaatgaag tcaacaggtg aagttatggg
    22441 ttctgatgct actttggaaa aagctctcta taaagccttt gaagcttctt atctacactt
    22501 gccaactttt ggtaatgtcg tctttaccat cgctgatgat gccaaagaag aagccttgaa
    22561 cttggctcgt cgtttccaaa acattggtta tggaatcctt gcgacagaag ggacagcagc
    22621 cttctttgct agtcatggct tgcaagccca acctgttggt aagattggtg atgacgataa
    22681 ggatatccca agttttgtac gcaaaggaag aattcaagct atcattaaca cagtaggaac
    22741 aaaacgaact gctgacgaag atggtgagca aattcgtcgt tcagccattg aacacggggt
    22801 gcccctcttc acagcgctag atacagctaa tgccatgctt aaggtacttg aaagtcgtag
    22861 ctttgttaca gaagcgattt aaatagaaaa aataagatat agcagcctga atttagaaca
    22921 gtacacaggg atactaaaat atttctagaa attaatttga attttctaat tgatttgttc
    22981 gcatcttatt tcaatctact atagaaaaaa gtctttaaaa ttataaaacg catcatatca
    23041 aggtttttca aaaaacttga tatgatgcgt tttattgtgg gaatatgtat ttcattttct
    23101 actaaaatta tgtttttgaa taacctctat cttagtagtc tgtataatcc ccctcaatca
    23161 gtttttgcga taagctttaa tgctatgact ataccactct tgcatttctt ttgatggtgg
    23221 tgtcatataa tcgccataca tctgggttaa aaattggtca tattttttgg gaacaggcaa
    23281 catacggccc tcaaactcag ttaaaatcag ttctttaaag gtatcaactg ggaagatttc
    23341 tttcatccct tccttaccga tcccaactcc tccttcatat tgaggagtgt tggttacagc
    23401 atttttgact agttgatcaa ttttcttgta aaagtagcga ggattgacaa atcggagagc
    23461 gtaccagcta cataatctaa gaaaatcttt tagtttgcta tcaccgtgaa ctgctcgtga
    23521 ttttttgata taagctagtt gacgaagagc cacatactta tagctcttgt cgacaatgct
    23581 caagtctgta aatcgatcaa ttgggaagac atcgatgaaa aggctggtat catgacgctt
    23641 gtacttaaca tggtcttcta taacagtaga agtgtccaaa atcgatgcga aattatggaa
    23701 gtaccaagaa gatgtatcgt aggaaagaac cttgtagcga gggtgatttt cttcttcaat
    23761 aatcttcagt aaacgctcat aatcctcacg ataaagggaa atatcaatat catcatccca
    23821 aggaatcata cctttgtggc ggatggctcc aagcatggtt ccataactga gaaaataagg
    23881 aatatcatgt ttcttacaag tctcatcaat atagtccagc agggctagtt gaatttcttt
    23941 aatttctttt ttttctaaat attgcatcct aatcctccaa tttataagcg tgaaattcat
    24001 gactgtagaa gcgtttttct tctggtggta gggtcatata atctccataa aattgtgtca
    24061 aaatagtatc aaatttttca ggtgcaggaa ggcttaaatt ctcaaaggtt aaatcgattg
    24121 ttttatcaaa ggtaccactt gggaagactt ccttttcctt aaattttgaa ggaataaaag
    24181 ccatatactg cccattttca cgactatatt tttgaatttc tttctcgatt ttatttgcaa
    24241 aataacgagg agaaaccggt cgaaggagca accaaaaggc tgttcgtatc caatctttta
    24301 aaaggctatc cttatagaca atatttttat gtttactgaa agacagcagt ttgaagcttt
    24361 ccagtttata acaagtatca atgaccttag gatcatcaaa gcgatctata gggaaaatat
    24421 cgataaagat accagactca taggtttttg tatttcgagt atcaataatt ttagtcgtac
    24481 tgtcggttat cttgataaag ttgttaaagt agttcttatc agtttctaag gataggagct
    24541 tatacttgct tttttccttt tgaaaaatgt taataaatcg ttggtagtct tctctaggca
    24601 tggacagatc aatatcgtcg tcccaaggga taaagccctc atgtcgaacc gccccaatca
    24661 gagtaccgta gttaataata tagttgatat tgtgcttttt acagagagta tcaatataat
    24721 ccaaaatttc taattcaatt tgtttggcat cttcaatggt tagttgtttc attttaaact
    24781 cctatgattt tttgaattta ttttttaagg ctaggacatg gtttaaaaat tcatagaaaa
    24841 tgctatcttt tgtgaagaca agtagactaa tataagagat agctgataac aagacaatca
    24901 aaccagtatt aatcaaaaat ggcaaattaa tgaccatatc cacaggatac acgaaattaa
    24961 tcaggaaata aattgctaca aaggaaagtg aaaagagaga gtatcgaaca gtatagctaa
    25021 agatatgtcc caagtggatg agttgttttc tatggatgaa aatgatatag aaaacaagta
    25081 gagaagtctc tgataacata gttgtcagta agtagtattc gggagccacg atatggttga
    25141 aaaagaggag actattcaag cccaaattga gtagcccagc aaagactgta tagactgtga
    25201 tacgtttttc atagccattg gtaaagagaa tttgggaacc aagaatggta tctaaggcca
    25261 ggataatcgt acgaaaagcg aagagagagg tcaagatgcc gcctccgata tatttttcac
    25321 taccgtaaag taggatggca tttggtccta aaaccatgag tccaaaactc agtggaatga
    25381 taaagaagtt aaagattcga ctacctctat taaccagaga aacataggct tctttgtctc
    25441 ctttccccag atagtaactg agacgaggca cactcactcc aattgcacct gttacaaccc
    25501 cagctataac ggtcacaatt cgctgagcta tggtatagta actaacgttg acatcaatcc
    25561 ctgttttaac gaggaagagg cgatctaaaa aagtgaagag catattggca ttggcaaaga
    25621 ctaacatggc tgtcagaggg agaaagagtg gtttaaaatc acttaggtga atcttaacaa
    25681 gtttgatgtc tcttttaatc caaaaataac taatcaggta gttaatcagc gtcgataaac
    25741 tcatcacaag tgtatagaca acaatatcgt gttcattttt aacaaataag aaaatagaga
    25801 ccagcatcag gatacggatg aaggcagttt tgtaaaagag aaaactgtaa ttttccagag
    25861 cttcattgac ccattcgatt gaaaaaatct gggcaatgag ttgaatcccc ataacaaggt
    25921 agaccttttt gacgattgga ttatcagtaa agaagagagg ataggctagg atatagacag
    25981 cagtggtcaa aatcgtacaa gcgatgcaca aataaaaaag actagaaaag gttctgttaa
    26041 gatctttttt gttatccttg acattactga tagcccttaa accgtagtta tagacaccat
    26101 aagttgcaaa gggcaagaaa aatgacaaaa tagtgtcgac tgagttgaag taaccatagt
    26161 cagttcggtc caagacacgc gcgacatagg ttccagttag gatgggaaaa ataatattca
    26221 agacacgaat tcccatgtaa gatagagcat ttaattttat acttttcatt caatttacct
    26281 cgtttttcat tatatcataa agttagctaa taagaaatga agggcagtaa gtcaagtaat
    26341 cactttgaag tttcaaatct taagttttaa gttttcttta aggaaagtat attattctga
    26401 aggactctaa aatttcgcag ccatttatta gtaattgcta cagaattcct agtcattact
    26461 agaaatggac tagtttcttt gaataataga actgcataat tctcctattc tagaagggga
    26521 ggaccagtat ttcttttatg ataggactag attgtggtat aatagagaga ataagttttt
    26581 ttagtaagac aaaggagaaa atagatgatt tatgcaggaa ttcttgccgg tggaactggc
    26641 acacgcatgg ggatcagtaa cttgccaaaa caatttttag agctaggtga tcgacctatt
    26701 ttgattcata caattgaaaa atttgtcttg gagccaagta ttgaaaaaat tgtagttggt
    26761 gttcatggag actgggtttc tcatgcagaa gatcttgtag ataaatatct tcctctttat
    26821 aaggaacgta tcatcattac aaagggtggt gctgaccgca atacaagtat taagaaaatc
    26881 attgaagcca ttgatgctta tcgtccgctt actccagagg atatcgttgt tacccacgat
    26941 tctgttcgtc catttattac acttcgcatg attcaggaca atatccaact tgcccaaaat
    27001 catgacgcag tggacacagt ggtagaagcg gttgatacta tcgttgaaag taccaatggt
    27061 caatttatta cagatattcc aaatcgtgct cacctttatc aaggacaaac acctcaaaca
    27121 ttccgttgca aggacttcat ggacctttat ggatctcttt ctgatgaaga gaaggaaatc
    27181 ttgacagatg catgtaaaat ctttgtgatc aaaggaaaag atgtggcctt ggccaaaggt
    27241 gaatactcaa atctgaagat tacaaccgta acagatttga agattgcaaa aagtatgatt
    27301 gagaaagact agtaaaatga ttaatcaaat ttatcaacta actaagccta agtttatcaa
    27361 tgtcaaatat caggaagagg ctattgacca agagaatcat atccttatcc gtcccaacta
    27421 catggctgtc tgtcatgcgg atcagcgtta ctatcaggga aaacgtgatc ccaagatttt
    27481 gaataaaaag cttccaatgg caatgattca cgagtcatgt ggaaccgtca tttctgaccc
    27541 gaccggaacc tacgaggttg gtcaaaaagt tgtcatgatt cccaatcagt ctcctatgca
    27601 gagtgatgaa gaattctatg aaaactacat gacagggacc catttcttgt ctagtggatt
    27661 tgatggcttt atgagagagt ttgtttctct ccctaaagat cgtgtggtgg cttatgatgc
    27721 tattgaagat acggttgcag ccattacaga gtttgtcagt gtgggcatgc acgctatgaa
    27781 tcgtctattg actcttgctc atagcaagcg ggagcggatc gccgttattg gagatggaag
    27841 tttagctttt gtggttgcca atattatcaa ctatactttg ccagaagcag agattgtggt
    27901 tattggtcgt cattgggaaa agttggaact cttctcattt gccaaagaat gctatattac
    27961 ggataatatt cctgaagatt tggcctttga ccatgctttt gaatgttgtg gtggtgatgg
    28021 tactggacca gctattaatg acttgattcg ctacattcgt cctcagggaa cgattctcat
    28081 gatgggagtt agcgaatata aagtcaatct caatactcgc gatgccttag aaaagggctt
    28141 gattttggtt gggtcatctc gttctggtcg cattgatttt gaaaatgcta tccaaatgat
    28201 ggaagtcaag aaatttgcca atcgtcttaa aaatatcctt tatctagaag aacctgtaag
    28261 agaaattaaa gatattcatc gtgtctttgc aaccgattta aacacagcct ttaaaacagt
    28321 gtttaagtgg gaagtataag tactggaggt taattgtgga gaaaatcatt aaagaaaaaa
    28381 tttcttcctt acttagtcaa gaagaggaag tcctcagtgt tgaacaactg ggtggaatga
    28441 ccaatcaaaa ctatttggcc aaaacaacaa ataagcaata cattgttaaa ttctttggta
    28501 aagggacaga aaagcttatc aatcgacaag atgaaaagta caatcttgaa ctactaaagg
    28561 atttaggctt agatgtaaaa aattatcttt ttgatattga agctggtatc aaagtaaatg
    28621 agtatatcga atctgcgatt acgcttgatt caacgtcaat caagaccaag ttcgacaaaa
    28681 ttactccaat attacaaact attcatacgt ctgctaagga attaagagga gaatttgctc
    28741 cttttgaaga aatcaaaaaa tacgaatcct tgattgaaga acaaattcct tatgccaact
    28801 atgaatctgt tagaaatgca gtcttctcct tagagaaaag actggctgac ttaggtgttg
    28861 acagaaaatc ttgtcatatc gatttggtgc ctgaaaactt tatcgaatca cctcaaggac
    28921 gactttattt gattgactgg gaatattcat caatgaatga tccaatgtgg gatttggctg
    28981 ccctcttttt agagtctgaa ttcacttccc aagaggaaga aactttctta tctcactatg
    29041 agagtgacca aacaccggtt tctcatgaaa agattgctat ttataaaatt ttacaagata
    29101 ctatttggag tctatggact gtctataagg aagagcaagg tgaagatttt ggtgactatg
    29161 gtgtgaatcg ttaccaaaga gctattaaag gtttggcttc ttatggaggt tcagatgaaa
    29221 agtaaaaacg gagttccttt tggccttctc tcaggtattt tctggggctt gggtctaacg
    29281 gttagtgctt atatcttttc gatttttaca gatttgtcac cctttgtggt ggctgcaact
    29341 catgattttt tgagcatctt tatcttacta gcttttctct tggtaaaaga agggaaagtt
    29401 cgcctctcaa ttttcttaaa tattcgcaat gtcagtgtta tcataggagc cttgctagca
    29461 ggccctatcg gtatgcaggc caatctttat gcagttaagt atatcggaag ttctttagct
    29521 tcatctgtat cggctattta ccctgcgatt tcagttctat tggctttctt ctttttgaag
    29581 cacaagattt cgaaaaatac tgtatttggg attgtcttga ttattggagg gattattgcc
    29641 cagacctata aggttgaaca ggttaattct ttctacattg ggattctttg tgctttggtt
    29701 tgtgctattg catggggaag tgagagtgtt cttagctctt ttgccatgga aagtgaattg
    29761 agtgaaatcg aagccctctt aatccgtcaa gtaacttcgt tcttgtccta tcttgtgatt
    29821 gtgctcttct ctcatcagtc atttgttgca gtagccaatg gacaattgct aggtctcatg
    29881 attgtctttg tagcctttga tatgatttcc tatttggctt attatatcgc tatcaatcgc
    29941 ttgcaaccag ccaaggctac aggcttgaac gtgagctatg tagtatggac tgtcttgttc
    30001 gcagctcttt tcttgggaac atcattagat atgctgacca ttatgacgtc acttgtcgtc
    30061 attgctggag tttatattat tattaaagaa taaaggagat tcgtgtgaaa gccattatct
    30121 tagcagcggg attgggaact cgcttgcgtc ctatgactga aaatacccct aaagccttgg
    30181 ttcaggttaa tcaaaaacct ttgattgaat accaaattga gtttctcaaa gaaaaaggaa
    30241 tcaatgacat catcatcatc gttggttatc ttaaagaaca attcgattat ttaaaagaaa
    30301 aatacggtgt tcgcctcgtt ttcaatgata aatacgctga ctacaataac ttttactctc
    30361 tctatcttgt aaaagaagaa ttggccaaca gctatgttat tgatgctgac aattatctct
    30421 ttaaaaatat gttccgcaat gatttgacac gttcgactta ttttagtgtt tatcgtgaag
    30481 attgtaccaa cgaatggttc ttggtctatg gagatgacta caaggttcaa gacattattg
    30541 ttgatagcaa ggcaggtcgc atccttagtg gtgtatcctt ctgggatgct ccaactgcag
    30601 aaaagattgt cagctttatc gacaaggctt atgcaagtgg tgaatttgtt gatctctact
    30661 gggacaatat ggttaaggat aatatcaaag agctagatgt ctatgttgaa gaattagaag
    30721 gcaatagcat ttatgagatc gatagtgtcc aagactatcg taaattagaa gaaattctta
    30781 aaaacgaaaa ttaaagattc caacatctga caaaatagtc ggatgttttt tgatttttta
    30841 cgaatagata gatgagtaga aaaagaaatg gagttattta tgaaaatcac aaactatgaa
    30901 atctataagt taaaaaaatc aggtttgacc aatcaacaga ttttgaaagt gctagaatac
    30961 ggtgaaaatg ttgatcagga gcttttgttg ggtgatattg cagatatctc aggttgccgt
    31021 aatccagccg tttttatgga acgttatttt cagatagacg atgcgcattt gtcgaaagag
    31081 tttcaaaaat ttccatcttt ctctatttta gatgactgtt atccttggga tttgagtgaa
    31141 atatatgatg cgcctgtact tttattttac aagggaaatc ttgacctcct gaaattcccg
    31201 aaggtagcgg tcgtgggcag tcgtgcttgt agcaaacagg gagctaaatc agttgaaaaa
    31261 gtcattcaag gcttggaaaa tgaactggtt attgtcagtg gtctggccaa gggcattgac
    31321 acagcagctc atatggcagc tcttcagaat ggcggaaaaa ccattgcagt gattggaaca
    31381 ggactggatg tgttttatcc taaagccaat aaacgcttgc aagactacat cggcaatgac
    31441 catctggttc taagtgaata tggacctggc gaacaacctc tgaaatttca ttttcctgcc
    31501 cgtaatcgca tcattgctgg actttgtcgt ggtgtgattg tagcagaggc taagatgcgt
    31561 tcaggtagtc tcattacgtg tgagcgagca atggaagaag gacgcgatgt ctttgctatt
    31621 cctggtagca ttttagatgg actatcagac ggttgccatc atttgattca agaaggagca
    31681 aaattggtca ccagtgggca agatgttctt gcggaatttg aattttaaaa atgacctaag
    31741 ctagaattct aagaaaaaat caattttaag agaaaatgaa cccaacattt ccataataaa
    31801 acgcatatta gcaagttttt aacacttgat aatatgcgtt ttttctaagt ggattagtag
    31861 agtagaggat ttttctcata taatactctt cgaaaatctc ttcaaactac gtcagcttcc
    31921 atctgcaacc tcaaaacagt attttgagct gacttcgtca gtcttatcta caacctcaaa
    31981 gcagtgcttt gagcaacctg tggctagctt cctagtttgc gctttgattt tcattgagta
    32041 taagggaaag tatagtgaat tgaaataaga tgtgaacaac tctatcagga aagtcaaatt
    32101 gatttataga aatattttag cagccaaggt gcactgttat agattcaata cactataatt
    32161 tagtgtaatt gagaaaggag aaatgattgt gattgatgtt ggctaggtta tgttcaatga
    32221 ttcctaccgt ctcaaatctt gtcagtaagg aaaaataaat tcttcaaaag tagagattac
    32281 aaggcttgtt taagaaagaa ttcaaagacc ttgacaaata aaaataaaat ggttattata
    32341 aaaaaatggt ctgaaataga tgatgatact tttcgaaaat ctcttcaaac tacgtcagct
    32401 cagctttgcc ttgctgtgtt ttgagcaagc tacggttagc ttccgagttt gattttcatt
    32461 tactagaaat gaaactgatg agagatatca gtagacattt gagtcaggat attatggaaa
    32521 atgataaaaa gagctcgtga gattggcata tcagactact aaagtattga gtttgttagg
    32581 attttagcga ctagttagct gggaaaggaa gatatttgtg acaaataata aactgtattc
    32641 gttgatagaa tttagaaata aaatatatga agaattagaa ctttccagaa gtgatttagc
    32701 gattttacta tgtgccatgc ttatcgcctc tatcggatta aatatggatt cgactcccgt
    32761 gattattgga gccatgttaa tctctccttt gatgacacct attctgggag tggggctctc
    32821 tctagctata tttgatttta aattgttaag aaaatctttt aaaatattag ctattcaaat
    32881 tcttgccagt ttaatagctt caacacttta tttttatctt tctcccattt cgtatgctag
    32941 ttcggaaatt gttgctagaa cctctccgac tatttgggat gttctcattg cttttgtagg
    33001 agggatagca ggtattattg gtgctaggaa aaaagagacc aataatattg ttcctggtgt
    33061 tgctattgca accgccttga tgcctcctct ttgtacagta ggttatgcta ttgcttctgc
    33121 taatctaaaa tttatcatag gctcctctta cctattcctc atcaattgta gctttattgt
    33181 cattgcgact tatataggtg ttaggttgat gatggttaag aaacattatt ttaaagataa
    33241 tgaagaagac tctaaaatgc gtaggatttt gcttctagtt gctgttttgc tgatgattcc
    33301 gagtttcatc tctgcaacga ctttagtgag agaaacgttg aaaaaagagt cccttaagaa
    33361 atttatatca gagcagtttc aggggtataa tattttgaaa aaaacctatt ctaaaaagac
    33421 tcatacccta aagctaacca tttcaggaaa ttatttgaca gaagaagaac tcgatatgat
    33481 ttcaagtaag agaggtgact atggtttaag tgatgtttct gttcaagttt cacaattgtc
    33541 tgattcagaa caacttagta aggaagagct ggtggagcat ttcttccagt atatcaagga
    33601 taaggaagca aaagaaaagg agaaagccaa taaatttgat acagagtctg aggagcaata
    33661 atttcttgag aatagctggt ttctctcgtg agtcttctat gtatatcaaa ggaagactga
    33721 ggttttaagt ataaaacttt tcttctatta tagtagctaa gtcttgacag ggttcaaaaa
    33781 atggtttaca ctttataaag tttattactt tgaaaaggtg tgatactgtg gctacggcaa
    33841 caaaaaagaa aaaatcaaca gttaaaaaaa atctagtcat cgtggagtcg cctgctaagg
    33901 ccaagacgat tgaaaaatat ctaggcagaa actacaaggt tttagccagt gtcgggcata
    33961 tccgtgattt gaagaaatcc agtatgtccg tcgatattga aaataattat gaaccgcaat
    34021 atatcaatat ccgaggaaaa ggccctctta tcaatgactt gaaaaaagaa gctaaaaaag
    34081 ctaataaagt ttttctcgcg agtgacccgg accgtgaagg agaagcgatt tcttggcatt
    34141 tggcccatat tctcaacttg gatgaaaatg atgccaaccg tgtggtcttc aatgaaatca
    34201 ccaaggatgc agtcaaaaat gcttttaaag aacctcgtaa gatcgatatg gacttggtcg
    34261 atgcccaaca agctcgtcgg atcttggatc gcttggtagg gtattcgatt tcgcctattt
    34321 tgtggaagaa ggtcaagaag ggcttgtcag caggtcgcgt tcagtccatt gcccttaaac
    34381 tcatcattga ccgtgaaaat gaaatcaatg ccttccagcc agaagaatac tggacagttg
    34441 atgctgtctt taaaaaggga accaaacaat ttcatgcttc cttctatgga gtagatggta
    34501 aaaagatgaa actgaccagc aataacgaag tcaaggaagt cttgtctcgt ctgactagta
    34561 aagacttttc agtagatcag gtggataaga aagagcgcaa gcgcaatgct cctttaccct
    34621 ataccacttc atctatgcag atggatgctg ccaataaaat caatttccgt actcgaaaaa
    34681 ccatgatggt tgcccaacag ctctatgaag gaattaatat cggttctggt gttcaaggtt
    34741 tgattaccta tatgcgtacc gattcgactc gtatcagtcc tgtagcgcaa aatgaggcgg
    34801 caagcttcat tacggatcgt tttggtagta agtattctaa gcacggtagc aaggtcaaaa
    34861 acgcatcagg tgctcaggat gcccatgagg ctattcgtcc gtcaagtgtc tttaatacac
    34921 cagaaagcat cgctaagtat ctggacaagg atcagctcaa gctatatacc cttatctgga
    34981 atcgttttgt ggctagccag atgacagcgg ccgtttttga taccatggct gttaaattgt
    35041 ctcaaaaagg ggttcaattt gctgccaatg gtagtcaggt taagtttgat ggttatcttg
    35101 ccatttataa tgattctgac aagaataaga tgttaccgga catggttgtt ggagatgtgg
    35161 tcaaacaggt caatagcaaa ccagagcaac atttcaccca accgcctgcc cgttattctg
    35221 aagcaacact gattaaaacc ttagaggaaa atggggttgg acgtccatca acctacgcgc
    35281 caaccattga aaccattcag aaacgttatt atgttcgcct ggcagccaaa cgttttgaac
    35341 cgacagagtt gggagaaatt gtcaataagc tcatcgttga atatttccca gatatcgtaa
    35401 acgtgacctt cacagctgaa atggaaggta aactggatga tgtcgaagtt ggaaaagagc
    35461 agtggcgacg ggtcattgat gccttttaca aaccattctc taaagaagtt gccaaggctg
    35521 aagaagaaat ggaaaaaatc cagattaagg atgaaccagc tggatttgac tgtgaagtgt
    35581 gtggcagtcc aatggtcatt aaacttggtc gttttggtaa attctacgct tgtagcaatt
    35641 tcccagattg ccgtcatacc caagcaatcg tgaaagagat tggtgttgag tgtccaagct
    35701 gtcatcaggg acaaattatt gagcgaaaaa ccaagcgtaa tcgcctattc tatggttgca
    35761 atcgctatcc agaatgtgaa tttacctctt gggacaagcc tgttggtcgt gactgtccaa
    35821 aatgtggcaa cttcctcatg gagaaaaaag tccgtggtgg tggcaagcag gttgtttgta
    35881 gcaaaggcga ctacgaggaa gaaaagatta aataagagga ggggcccgaa agtaaatttc
    35941 aggctccttt tggttagaac ttgacaaaat acatcatttt atgcgaaact agaagaagat
    36001 tattttatac tcaatgagaa tcaaagagca aattagaaag ctagtcgcag gttgctcaaa
    36061 gcactacttt gaggttgaag atggaagctg acctggtttg aagagatttt cgaagagtat
    36121 taactaggag aagttatgcg tattatctat ctaattattg gttttttatc gctgaccttg
    36181 gctattgttg gggttgtttt acccttgttg cctacaacac ctttcctttt gttgtctatt
    36241 gcttgtttct ccagaagttc caagcgattc gaagattggc tttatcatac caagctctat
    36301 caagcatatg tagctgattt tcgtgagacc aagtctattg cgcgtgaacg aaagaaaaaa
    36361 atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc tcttttacca
    36421 gtcaaaatcg gtctgggtgc tttgaccatc tttattactt attatctctt caaggtcatt
    36481 ccagacaaag aatagttaaa acagtagtta tttgccttga taaaattgaa agcatattca
    36541 taacaatatg atataataaa attgaagtaa tattcaagga gaatcaaatg atttacgaat
    36601 tttgtgctga aaatgtgact ttacttgaaa aagcgatgca ggctggagct cgtcggattg
    36661 aactctgtga taatctagca gttggtggga caacacccag ctatggagtg actaaggcag
    36721 cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg ccacgtggtg
    36781 gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt cgtttgactg
    36841 ctcaggctgg aagtcaaggg gttgtatttg gagctttaac tgctgataaa aagttggata
    36901 agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc tttcacatgg
    36961 cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc agtcaagccg
    37021 gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa aaacgttttg
    37081 ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta ccaggtgggg
    37141 ggattgacct tgaaaaccgt caaaccttta tcgaccaggt gggggtaaca caattgcatg
    37201 gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta gcagttttca
    37261 cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca tgattatggt
    37321 tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg tgactttgtc
    37381 atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca agagactggt
    37441 gacctctatc ctcacgttta tatggaaagc atgaggggaa gttttgtcgg aaatgtccgt
    37501 gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt gcaagatttt
    37561 atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg aaaccagttg
    37621 gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg caatcaaaag
    37681 tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag agaaggacaa
    37741 gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tgctttcaca aaaggggatt
    37801 tatccagcct tccatatgag caagcgctac tggattagtg tgtcccttga tgatacttta
    37861 tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc taaaaaatga
    37921 aatattttaa taattttcat gaactttcaa ttagctaaat attctttact gaagagattt
    37981 ttagaaaata taggatttac cacactagag gaatatggtg ccatcttcaa atacctgatt
    38041 gagaatgtca agacggatcg tcagatcatc tattcgcctc actgtcatga tgacctcgga
    38101 atggcagtgg caaatagcct tgctgctgtc aagaatggtg caggacgtgt tgaagggact
    38161 atcaatggta ttagggagcg agctgaaaat gctgctttgg aagaaattgc agtggctctc
    38221 aatattcgcc aagattacta ccaagtagaa accagtattg tcctaaatga gaccatcaat
    38281 acgtcagaaa tggtttctcg cttctctggt attccagttc ctaaaaacaa agccgtcgtt
    38341 ggtggcaata ccttctccca cgaatctggt attcaccaag atggagtcct taaaaatcct
    38401 ctcacttatg agatcatcac acctgaattg gttggtgtta agattctgct tggaaaatta
    38461 tctggtcgcc atgcttttgt tgagaaactg agagaattgg ccctagattt tacagaagag
    38521 gatatcaaac cactctttgc taagttcaag gcactggtcg ataagaagca agaaatcaca
    38581 gatgcagata ttcgagcttt ggtagctgga accatggttg aaaatccaga aggcttccac
    38641 tttgatgatt tacaacttca aactcatgca gataatgaca ttgaagcgct cgttagccta
    38701 gccaatatgg atggtgagaa agtcgaattt aatgcgacag ggcaaggttc cgttgaagca
    38761 atctttaatg ctatcgataa gttctttaac caatctgttc gtttggtgtc ctacactatc
    38821 gatgcggtaa cagatggaat cgatacccag gatcgggttt tggtcactgt tgaaaacaga
    38881 gatacagaaa ccatctttaa tgcagcaggg cttgattttg atgtgttgaa ggcttctgct
    38941 attgtctata taaacgctaa tacctttgtt caaaaagaga atgcaggtga gatgggacgc
    39001 agtgtttctt accacgatat gcctagtgtg taaaggagaa ggctatggca aagaaaatag
    39061 tagctctagc aggagacgga attggcccag aaatcatgga ggttggttta gaagttctgg
    39121 aggctctagc tgaaaaaaca ggttttgact atgagattga cagacgaccg ttcggaggcg
    39181 cagatattga tgcagcatga cctcccttac ctgatgaaac ccttaaggca agtagggaag
    39241 cagatgctat cctactagta gctatcggta gtcctcagta tgatggagca gtggttcgcc
    39301 ctgaacaagg cctgatggct ctccgtaagg aactcaatct ttacgctaat attcgtcctg
    39361 taaaaatctt tgacagtctc aagcatttgt cactactcaa actggaacga attgctggtg
    39421 tagactttgt cgtggtgcgt gaattgacag gcgggattta ctttggagat catattcttg
    39481 aagagcgcaa tgcgcgtgat atcaacgact atagctatga ggaagtggag cggattattc
    39541 gcaaagcctt tgaaattgca agaaatcgca gaaaaatcgt tactagtatc gataagcaaa
    39601 atgttctagc gacctcaaaa ctctggcgga aagtagctga ggaagtcgca caggatttcc
    39661 cagatgtaac cttggaacat cagctggtag actcagctgc tatgcttatg attaccaatc
    39721 ctgctaagtt tgatgttatt gtaacggaga atctttttgg agatatttta tctgatgaat
    39781 caagcgtctt atctggtaca cttggggtta tgccatcagc cagtcattct gaaaatggac
    39841 caagtctcta tgaacctatt cacagttcag cacctgatat tgcaggtcaa ggaattgcca
    39901 atcctatttc catgatttta tcagtttcca tgatgttgag agatagtttc ggacgttatg
    39961 aggatgcaga gcgtatcaaa cgtgctgttg agacaagtct ggcggcagga attttaacga
    40021 gagatatagg aggtcaggct tcaacaaagg aaatgacgga agctattatt gcaaggttat
    40081 gaagttagac gaaaaaatta ctctagtcct tttgatttgg aatgtcatca ttttcttgat
    40141 ttatggtatt gacaaatcta aggcaaggag aagagtttgg cgcatccctg agaaaatctt
    40201 acttatttta gcctttactt ttggtggttt tggtgcctgg ctagcaggaa tcatctttca
    40261 ccacaagact cgaaaatggt actttaaaat agtttggttt cttgggatgg tgaccacact
    40321 agtagcctta tattttattt ggaggtaatg gatggcaggg tcttcgaggg aatacgctgc
    40381 ttgggctcta gcggactatg gttttaaggt cgtgattgca ggatctttcg gtgacattca
    40441 ttacaataat gaactcaata atggcatgtt gccaatcgtt cagcctagag aggttagaga
    40501 gaaactagcc cagctaaaac caaccgacca ggtaactgtg gacttggaac aacaaaaaat
    40561 catctcacca gttgaagaat tcaccttcga gatagatagc gagtggaaac ataaactcct
    40621 aaatagtttg gatgatatcg gtattacctt gcagtatgaa gagttgattg ctgcttatga
    40681 aaaacaacga ccagcctact ggcaggatta gaaaaaatag aaaaggagat atagtaaact
    40741 gaaataagat gtaaacaaat gaattggagc ttaacatcca tttccagcaa ttttttagaa
    40801 actacagtgg actattctgg attcaacaca ttataaaatt atgacaaaac acattcacaa
    40861 gaaggctacg acattttaaa aggtgagggc ggatgtatcg tttgccctac taaagttggt
    40921 tacattatca tgaccagtga caaggcagga cttgagcgta agttcgcagc caaagaacgt
    40981 aagcgtaaca aaccaggtgt tgttctctgc ggtagcatgg atgaactttg cgctttagcg
    41041 caactcaacc cagaaattga agcattctac taaaaacatt gggatgaaga tattcttctt
    41101 ggttgtatcc ttccttggaa accagaagcc tttgaaaaac tcaaagcata cggggatggc
    41161 cgtgaagaac ttattactga tgtacgtggt actagctgtt ttgttatcaa gtttggaaaa
    41221 gcaggtgaac aattggctgc caagctttgg gaagaaggta aaatggtcta cgcctcatct
    41281 gcttcaatga caaaacgatt gaaactcgct atgagcaagg tgtaatggtg tctatggtcg
    41341 ataaggacgg caaactcatc ccagaacaag gaggagcacg ttcaacttca ccagctccag
    41401 ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca gatactttta
    41461 actcatggga ctaccgtcag gttgagtatt attaggatag agaagaagtc tagtgttatg
    41521 agatattaaa gctcctaaca ctgggctttt gtttagaatt tcttttcttt ttctatagga
    41581 tatggtattc tatgtagaaa atatatgtta ataagtaatg ccaatattta aacatcatta
    41641 gtaaaaggag ttagattgat gaataaaaga aaagttagtt tagaagattt ttataaatgg
    41701 tatagtctaa ataaagaaga gttattaaat aaggcaactg ttggtgaaaa gtttaatgat
    41761 aaattaaaag aagagtttct ccaggaatgg cctttggata ggattttaac aatgtcaatc
    41821 gatgaatatg taataggaaa gggacagcaa aataagtctt tatgctacgc tcttgagaag
    41881 ggaaaataca aaaatctatt tcttggaatt tctggtggct cagcttcaaa atttggtatt
    41941 tattggaata aaaaaacaaa caaatataaa gatcaagcta ataatgagat ttcagagttg
    42001 gatcagcgat tt
//
LOCUS       DBERDS010000015        39680 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.015, whole genome shotgun sequence.
ACCESSION   DBERDS010000015 DBERDS010000000
VERSION     DBERDS010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.015"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..237
                     /locus_tag="ACL73E_000902"
     CDS             <1..237
                     /locus_tag="ACL73E_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000967644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800894.1"
                     /translation="ISVNYEITEDEDFETVKTRVISDFESYLKLLNGKFEESLKKVIK
                     SFTFSKLIGEKLCNGEDLKNLSKEIRHQIQDRNS"
     gene            500..1777
                     /locus_tag="ACL73E_000903"
     CDS             500..1777
                     /locus_tag="ACL73E_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGS0800895.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1853..3337
                     /gene="thrC"
                     /locus_tag="ACL73E_000904"
     CDS             1853..3337
                     /gene="thrC"
                     /locus_tag="ACL73E_000904"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGS0800896.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDTSYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3398..4678
                     /locus_tag="ACL73E_000905"
     CDS             3398..4678
                     /locus_tag="ACL73E_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS0800897.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4682..5302
                     /locus_tag="ACL73E_000906"
     CDS             4682..5302
                     /locus_tag="ACL73E_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0800898.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5468..6580
                     /locus_tag="ACL73E_000907"
     CDS             5468..6580
                     /locus_tag="ACL73E_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGS0800899.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6903..7328
                     /locus_tag="ACL73E_000908"
     CDS             6903..7328
                     /locus_tag="ACL73E_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS0800900.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAIQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7339..7740
                     /locus_tag="ACL73E_000909"
     CDS             7339..7740
                     /locus_tag="ACL73E_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGS0800901.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKIHLKVDSNLANPF"
     gene            7815..8459
                     /gene="pcp"
                     /locus_tag="ACL73E_000910"
     CDS             7815..8459
                     /gene="pcp"
                     /locus_tag="ACL73E_000910"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGS0800902.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(8487..9344)
                     /locus_tag="ACL73E_000911"
     CDS             complement(8487..9344)
                     /locus_tag="ACL73E_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGS0800903.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFILDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9474..10616
                     /gene="tgt"
                     /locus_tag="ACL73E_000912"
     CDS             9474..10616
                     /gene="tgt"
                     /locus_tag="ACL73E_000912"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGS0800904.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10717..12534
                     /locus_tag="ACL73E_000913"
     CDS             10717..12534
                     /locus_tag="ACL73E_000913"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGS0800905.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHIILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12687..13838
                     /gene="nagA"
                     /locus_tag="ACL73E_000914"
     CDS             12687..13838
                     /gene="nagA"
                     /locus_tag="ACL73E_000914"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGS0800906.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14001..15059
                     /locus_tag="ACL73E_000915"
     CDS             14001..15059
                     /locus_tag="ACL73E_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGS0800907.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15210..15575
                     /locus_tag="ACL73E_000916"
     CDS             15210..15575
                     /locus_tag="ACL73E_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGS0800908.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15651..16592
                     /gene="comGA"
                     /locus_tag="ACL73E_000917"
     CDS             15651..16592
                     /gene="comGA"
                     /locus_tag="ACL73E_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGS0800909.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16540..17556
                     /gene="comGB"
                     /locus_tag="ACL73E_000918"
     CDS             16540..17556
                     /gene="comGB"
                     /locus_tag="ACL73E_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGS0800910.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17558..17884
                     /gene="comGC"
                     /locus_tag="ACL73E_000919"
     CDS             17558..17884
                     /gene="comGC"
                     /locus_tag="ACL73E_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGS0800911.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVND"
     gene            17877..18281
                     /gene="comGD"
                     /locus_tag="ACL73E_000920"
     CDS             17877..18281
                     /gene="comGD"
                     /locus_tag="ACL73E_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGS0800912.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18244..18546
                     /gene="comGE"
                     /locus_tag="ACL73E_000921"
     CDS             18244..18546
                     /gene="comGE"
                     /locus_tag="ACL73E_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGS0800913.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18509..18970
                     /gene="comGF"
                     /locus_tag="ACL73E_000922"
     CDS             18509..18970
                     /gene="comGF"
                     /locus_tag="ACL73E_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGS0800914.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            18948..19361
                     /gene="comGG"
                     /locus_tag="ACL73E_000923"
     CDS             18948..19361
                     /gene="comGG"
                     /locus_tag="ACL73E_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGS0800915.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            19498..20092
                     /locus_tag="ACL73E_000924"
                     /pseudo
     CDS             19498..20092
                     /locus_tag="ACL73E_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20153..21106
                     /locus_tag="ACL73E_000925"
     CDS             20153..21106
                     /locus_tag="ACL73E_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0800916.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYTHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21157..22347
                     /locus_tag="ACL73E_000926"
     CDS             21157..22347
                     /locus_tag="ACL73E_000926"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGS0800917.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFSCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22348..22479
                     /locus_tag="ACL73E_000927"
     CDS             22348..22479
                     /locus_tag="ACL73E_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800918.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            22496..22867
                     /gene="rnpA"
                     /locus_tag="ACL73E_000928"
     CDS             22496..22867
                     /gene="rnpA"
                     /locus_tag="ACL73E_000928"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGS0800919.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22842..23666
                     /locus_tag="ACL73E_000929"
     CDS             22842..23666
                     /locus_tag="ACL73E_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGS0800920.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23685..24671
                     /gene="jag"
                     /locus_tag="ACL73E_000930"
     CDS             23685..24671
                     /gene="jag"
                     /locus_tag="ACL73E_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGS0800921.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24722..25345
                     /locus_tag="ACL73E_000931"
     CDS             24722..25345
                     /locus_tag="ACL73E_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGS0800922.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25476..26933
                     /locus_tag="ACL73E_000932"
     CDS             25476..26933
                     /locus_tag="ACL73E_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0800923.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            26956..27237
                     /locus_tag="ACL73E_000933"
     CDS             26956..27237
                     /locus_tag="ACL73E_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0800924.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27314..27799
                     /locus_tag="ACL73E_000934"
     CDS             27314..27799
                     /locus_tag="ACL73E_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0800925.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27816..28481
                     /locus_tag="ACL73E_000935"
     CDS             27816..28481
                     /locus_tag="ACL73E_000935"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGS0800926.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28485..29348
                     /locus_tag="ACL73E_000936"
     CDS             28485..29348
                     /locus_tag="ACL73E_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGS0800927.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29350..30054
                     /locus_tag="ACL73E_000937"
     CDS             29350..30054
                     /locus_tag="ACL73E_000937"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGS0800928.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30233..31906
                     /locus_tag="ACL73E_000938"
     CDS             30233..31906
                     /locus_tag="ACL73E_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0800929.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEQEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32018..33109
                     /gene="ulaG"
                     /locus_tag="ACL73E_000939"
     CDS             32018..33109
                     /gene="ulaG"
                     /locus_tag="ACL73E_000939"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGS0800930.1"
                     /translation="MPNVKEITRELWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RINVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLTVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33223..35199
                     /gene="tkt"
                     /locus_tag="ACL73E_000940"
     CDS             33223..35199
                     /gene="tkt"
                     /locus_tag="ACL73E_000940"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS0800931.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAIEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35316..35615
                     /gene="yajC"
                     /locus_tag="ACL73E_000941"
     CDS             35316..35615
                     /gene="yajC"
                     /locus_tag="ACL73E_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS0800932.1"
                     /translation="MNPNYTFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35662..36090
                     /locus_tag="ACL73E_000942"
     CDS             35662..36090
                     /locus_tag="ACL73E_000942"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGS0800933.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36092..36502
                     /locus_tag="ACL73E_000943"
     CDS             36092..36502
                     /locus_tag="ACL73E_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGS0800934.1"
                     /translation="MENPTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36803..39454
                     /gene="adhE"
                     /locus_tag="ACL73E_000944"
                     /gene_synonym="adhC"
     CDS             36803..39454
                     /gene="adhE"
                     /locus_tag="ACL73E_000944"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGS0800935.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12152 a         7044 c         8874 g        11610 t
ORIGIN      
        1 atatcagtca attatgaaat tactgaagac gaagactttg agaccgtcaa aacgagagtg
       61 atatcagatt ttgaaagcta tttgaagctt ctaaatggca agtttgaaga aagtctcaag
      121 aaagttatta agtcttttac ctttagtaaa ctcattggag aaaaactatg taatggtgaa
      181 gacctaaaaa atttaagtaa agaaataagg catcaaatcc aagataggaa ttcctaaaaa
      241 attactaaaa actaaaataa ttattgtttt tatagtataa ctaatttctt aaaacattga
      301 attaatctga attatgacgt aagtctgcta atttcactgc tctcaaaatc cagtgtccgc
      361 aaggacgtgc cggttcgacc ccggccgccg gtatagtata gtgttaggaa cgttgttatt
      421 cttcgttctt tttttatatt atttttggta taattatagt tattcaaatt ttatttagat
      481 taagaaagtg tagggtagta tgtcttgttc tatcgattta ttaaaacatc ggtatttgaa
      541 aaatattaaa gaaaatcctg aattgtttgt cggaattgag ttggagtatc ctgttgcaag
      601 tttagaaggg gatgctacag atgttgaagt tataaaggat ctatttcatt atttagtttc
      661 tactttggat ctcaccgtag caaaggtaga tgattttggc aatctgatcc agttagtaga
      721 tccgataagt caggatgcta ttttatttga agtttcctat acaacgattg agtttgcatt
      781 tggtaaggct gaaacgattc aagaggtcga aaatcgtttc aataattata tgaatgtaat
      841 tcagagaaag ttagctgaat caaatcatgc tattgttggc tgtggtatcc atcccaactg
      901 ggataaaaat gagaattgtc cagtggctta tccacgctat cagatgttga tggattattt
      961 gaatttgagt agaaatatta ttaaatcaga tttacatcat ttccctgaat atggtacttt
     1021 tatctgtggg agccaggttc agctggatat ttcaaaaacc aactacttac gggtgattaa
     1081 tgcttttact caaattgaag cggctaaggc ttatttattt gcaaactctg aattttcggg
     1141 tgcggattgg gatacgaaaa tttcaaggga tattttctgg gaagaatcta tgcatggtat
     1201 ctatccagag aatgttgggg tcaatgctag actccttaat gatgaagctg atttttttga
     1261 ctatctaaat cattctgcga tttttactgc ggaacgtgat gggcagacct attattttta
     1321 tcctattcag gctggggact atttggctac gcctgaaatc caagcatttg ctctgaatgg
     1381 ggatgaggtt attatttccc cccaagagaa ggattttgaa actcatcgta gttaccagta
     1441 ccaagactta acgactcgag gaacagttga gtttcgtagt gtgtgtacac agccacttga
     1501 taggactttt gcttctgcag cttttcactt gggattattg gttaatttag acaagttaga
     1561 agcttactta gaaacagcac ctttctttaa agtatttggt tatgattaca agtctttaag
     1621 gagacaattt tctaagaaaa atcttacaga tgaggaagaa actacgatta ttgaattttc
     1681 caaagactta ctcctactag ctgaggaggg actagtggtg agaaataagg aagaaatgac
     1741 ctatttacag cctttgagag aagaattgag cctataattt ctcttataaa gggagaattt
     1801 tctgaaaaat catgatataa tggacgagac tatagataaa ggatagagag taatgacatt
     1861 agtttatcaa tcaacgcgtg atgccaacaa tacagtaact gctagccaag caattttgca
     1921 aggtttggcg acggacggcg gtttgtttac accggttact tatccaaagg tagatttgga
     1981 ctttgacaaa ttgaaagata cttcttacca ggaagttgct aagctagttt tgtcagcatt
     2041 tttagatgac tttacagctg aggagttgga ctactgtatc aacaatgcct acgatagcaa
     2101 atttgatact ccagctattg caccattagt gaaattagat gggcaataca atttggaact
     2161 tttccatggt tcaacgattg cctttaagga tatggccttg tctattttgc catactttat
     2221 gacgactgct gctaagaaac atggtttgga gaacaagatt gttatcttga cagcgacatc
     2281 tggtgacacg gggaaagctg ctatggcggg gtttgcggat gtgcctggta ctgagattat
     2341 cgtcttttat ccaaaggatg gtgtcagcaa gattcaagag ttacaaatga ccactcaaac
     2401 tggcgacaat actcatgtta ttgctattga tggtaacttt gacgatgcgc aaacaaatgt
     2461 gaagcacatg tttaacgacg tggctcttcg tgaaaaattg actaccaaca agttgcaatt
     2521 ttcatcagct aactctatga acattggtcg tctggtgcca caaattgttt attatgttta
     2581 tgcttacgct caattggtta agactggtga aattgtagct ggtgaaaagg ttaacttcac
     2641 agtaccaaca ggaaactttg gaaatatctt ggctgccttt tatgccaaac aaattggttt
     2701 gccagttggt aaattaatct gtgcttcaaa tgacaacaat gttttgacag acttctttaa
     2761 aacacgtgtc tatgacaaaa aacgtgagtt taaggtaaca accagcccat ctatggatat
     2821 cttggtatct tcaaacttgg agcgcttgat tttccatctt ttgggaaata atgctgaaaa
     2881 gacaactgaa cttatgaatg ccttgaacac gcaaggacaa tataagttga cagactttga
     2941 tgcagagatt ttggacctct ttgcagctga atatgcgact gaggaagaaa cggcagcaga
     3001 gatcaagcgt gtttgtgagt tagattctta tatcgaggac cctcatacag ctgttgcttc
     3061 agcagtttat aaaaaatacc aatcggccac tggagatgta actaagacag tgattgcttc
     3121 aacagctagt ccatacaagt tcccagtagt tgcagtagaa gctgtaactg gaaaagcagg
     3181 tttaacagac tttgaagcct tggctcaatt acatgaaatc tcaggcgttg cagtgccacc
     3241 agcagttgat gggcttgaaa tagctccaat tcgtcacaag acaacagtgg cagctgctga
     3301 catgcaagca gcggttgagg cttatttagg actttaagac agagggagca aactcggttg
     3361 ggaaaccaac tgagtttctt ttcatcagga ggagagattg tttaagaaaa ataaagacat
     3421 tcttaatatt gcattgccag ctatgggtga aaactttttg cagatgctaa tgggaatggt
     3481 ggacagttat ttggttgctc atttaggatt gatagctatt tcaggggttt cagtagctgg
     3541 taatattatc accatttatc aggcgatttt catcgctctg ggagctgcta tttccagtgt
     3601 tatttcaaaa agcatagggc agaaagacca gtcgaagttg gcctatcatg tgactgaggc
     3661 gttgaagatt accttactat taagtttcct tttaggattt ttgtccatct tcgctgggaa
     3721 agagatgata ggacttttgg ggacggagag ggatgtagct gagagtggtg gactgtatct
     3781 atctttggta ggcggatcga ttgttctctt aggtttaatg actagtctag gagccttgat
     3841 tcgtgcaacg cataatccac gtctgcctct ctatgttagt tttttatcca atgccttgaa
     3901 tattcttttt tcaagtctag ctatttttgt tctggatatg gggatagctg gtgttgcttg
     3961 ggggacaatt gtgtctcgtt tggttggtct tgtgattttg tggtcacaat taaaactgcc
     4021 ttatgggaag ccaacttttg gtttagataa ggaactgttg accttggctt taccagcagc
     4081 tggagagcga cttatgatga gggctggaga tgtagtgatc attgccttgg tcgtttcttt
     4141 tgggacggag gcagttgctg ggaatgcaat cggagaagtc ttgacccagt ttaactatat
     4201 gcctgccttt ggcgtcgcta cggcaacggt catgctgttg gcccgagcag ttggagagga
     4261 tgattggaaa agagttgcta gtttgagtaa acaaaccttt tggctttctc tgttcctcat
     4321 gttgcccctg tcctttagta tatatgtctt gggtgtacca ttaactcatc tctatacgac
     4381 tgattctcta gcggtggagg ctagtgttct agtgacactg ttttcactac ttgggacccc
     4441 tatgacgaca ggaacagtca tctatacggc agtctggcag ggattaggaa atgcacgcct
     4501 ccctttttat gcgacaagta taggaatgtg gtgtatccgc attgggacag gatatctgat
     4561 ggggattgtg cttggttggg gcttgcctgg tatttgggca gggtctctct tggataatgg
     4621 ttttcgctgg ttatttctac gctatcgtta ccagcgctat atgagcttga aaggatagga
     4681 aatgcaaaaa acagctttta tttgggattt agacgggact ttattggact cttacgaagc
     4741 gattttatca gggattgagg agacttttgc tcagttttct attccttatg ataaggagaa
     4801 ggtgagagag tttatcttca agtattcggt gcaagatttg cttgtgcggg tggcagaaga
     4861 tagaaatctg gatgttgagg tgctaaatca ggtgcgtgcc cagagtctgg ctgagaagaa
     4921 tgctcaggta gttttgatgc caggtgcgcg tgaggtgcta gcttgggcag acgaatcagg
     4981 aattcagcag tttatatata ctcataaggg gaacaacgct tttaccattc tcaaggactt
     5041 gggggtggaa tcctatttta cagagatttt aaccagtcag agtggctttg tgcggaagcc
     5101 aagtccagaa gcggctacct atctgctaga taagtatcag ttgaattctg ataatactta
     5161 ttatataggg gatcggactc tggatgtgga atttgcccag aatagtggga ttcaaagcat
     5221 caacttttta gagtctactt atgaagggaa tcacaggatt caagcgttag cagatatttc
     5281 ccgtattttt gagactaagt gataaaaaga ttgtgtcagt tttgtgacag agacctaaca
     5341 aactatttca agtaacctag tttgttacaa ggaatagaca gttctgttaa ataggcccga
     5401 gagggctttt tttctacatt ttttgtgtta tgatagacag gtactcattt gaaaggaatt
     5461 tgaaagaatg aagaaaagaa tgttattagc gtcaacagta gccttgtcat ttgccccagt
     5521 attggcaact caagcagaag aagttctttg gactgcacgt agtgttgagc aaatccaaaa
     5581 cgatttgact aaaacggaca acaaaacaag ttataccgta cagtatggtg atactttgag
     5641 caccattgca gaagccttgg gtgtagatgt cacagtgctt gcgaatctga acaaaatcac
     5701 taatatggac ttgattttcc cagaaactgt tttgacaacg actgtcaatg aagcagaaga
     5761 agtaacagaa gttgaaatcc aaacacctca agcagactct agtgaagaag tgacaactgc
     5821 gacagcagat ttgaccacta atcaagtgac cgttgatgat caaactgttc aggttgcaga
     5881 cctttctcaa ccaattgcag aagttacaaa gacagtgatt gcttctgaag aagtggcacc
     5941 atctacgggc acttctgtcc cagaggagca aacgaccgaa acaactcgcc cagttgaaga
     6001 agcaactcct caggaaacga ctccagctga gaagcaggaa acacaagcaa gccctcaagc
     6061 tgcatcagca gtggaagtaa ctacaacaag ttcagaagca aaagaagtag catcatcaaa
     6121 tggagctaca gcagcagttt ctacttatca accagaagag acgaaagtaa tttcaacaac
     6181 ttacgaggct ccagctgcgc ccgattatgc tggacttgca gtagcaaaat ctgaaaatgc
     6241 aggtcttcaa ccacaaacag ctgcctttaa agaagaaatt gctaacttgt ttggcattac
     6301 atcctttagt ggttatcgtc caggagacag tggagatcac ggaaaaggtt tggctatcga
     6361 ctttatggta ccagaacgtt cagaattagg ggataagatt gcggaatatg ctattcaaaa
     6421 tatggccagc cgtggcatta gttacatcat ctggaaacaa cgtttctatg ctccattcga
     6481 tagcaaatat gggccagcta acacttggaa cccaatgcca gaccgtggta gtgtgacaga
     6541 aaatcactat gatcacgttc acgtttcaat gaatggataa acccgacttg ataacatcat
     6601 tttgacgaat gagatctagc tttcgtgatg gaaagcgatt ctcgttcgtt ttttctttgt
     6661 catactcttc gaaaatctct tcaaaccacg tcagttttat ctgaaacctc aaagctgtgc
     6721 tttgagcaac ctgcgactag cttcctagtt tgctttttga ttttcattga gtatcaattt
     6781 gaatggaaaa tggaaagtta tcatcttgta atgagttaag caacattctt gcaatctatt
     6841 ttactttata tcacaattaa ttagtcaact attgataaat caataaaaag agaggggaag
     6901 aaatgctaga gattcaagat ttactgtatc aactccgctt gtctgagcaa gcgagtacgc
     6961 aattgtttga aaaaaggctt gggattagtt tgacacggta tcagatttta ctgtttttgc
     7021 tggagcattc tccttgtaac caaatggcga ttcaggagcg tttgaaaatt gatcaggctg
     7081 ctttgacacg gcatttcaag attttggaaa cggaaggttt ggtggagcgt catcgtaatc
     7141 ctgaaaatca gcgggaagtg ttggtagagg ctgcgaagta tgccaaggag cagttagtgg
     7201 tgaatccccc tctgcaacat atcaaggtta aggaagagat ggaaagtatc ttaacagagt
     7261 ttgagagaac agaactcagc cgtttattaa ataaattggt tttgggtatt gaaaatatag
     7321 aaatttaagg agaaatagat gtcaattatt acaattattt taacaacgat cgttgctttg
     7381 gagcattttt acatttttta tttggaaagt attgctacgc gatcagatgc gactagtcgt
     7441 gtatttaata tggaaaagga agaattggct catccgtcag taagttcatt gttcaaaaat
     7501 caagggattt ataaggctct gctaggagtc tttctctggt atggcattta tttctcacag
     7561 aatttagaaa ttgtgactat ttttgtctta tttgtgattg gtgctgcgac ttacggctct
     7621 ttaacagcgg ataaaaaaat tattttgaag caaggtggat cagctatttt ggccttgatt
     7681 agtattttac tctttaaaat acacttgaag gtcgattcta atctcgctaa tcctttttaa
     7741 tccagaataa gggaaatatg ttatacttgt ttttaagaaa aaagtctcat tgaattggtt
     7801 ttgaggagtt agaaatgaaa gtattagtga caggttttga gccctttgga ggggaaaagg
     7861 gcaatccaac tttggaggcc attaaaggtt taccagctga aatccatggt gctgaggtcc
     7921 gttggctaga ggtgccgaca gtttttcaca aatctgctca agtattggaa gaagagatga
     7981 atcgttatca acctgacttt gtcctttgta ttgggcaagc tggtggaaga actagtgtga
     8041 cacctgaacg agtggccatt aatcaagacg atgcacgcat ttctgataac gaagataatc
     8101 aaccgattga ccgtcccatt cgcccagatg gtgcttcggc ctactttagt agtttgccga
     8161 ttaaagcgat ggttcaagct ataaaaaaag agggcttacc ggcctctgtt tccaatacgg
     8221 cagggacttt tgtctgcagc catttgatgt atcaggctct ctatttggta gaaaagaaat
     8281 ttccatatgt taaggcaggt tttatgcata ttccttatat gatggaacag gtggtgaaca
     8341 gaccgactac tccaactatg agtttagtgg atattcggcg agggatagaa gcagcaatcg
     8401 gcgctatgat agaacatggg gatcaggaac tcaagttggt aggcggagaa actcattgat
     8461 agaaaaaagc ttgaggggaa aaaccttcaa gcttttggac gttttcgagc caatactgct
     8521 cggtaaaaca taattttagt gcattggata taaggtagga gtgaaaaact agcaatgcca
     8581 aaggtaatcc aattgaggaa gtaccaagga agaagctgta aatctaggat aaagtgctgg
     8641 aacttgtagc ccttcataaa ggaacggcta gtttttagga ttcgtcttgg tgggacctgt
     8701 cctaggtcta gactataaca gagaagaaat tccacctgtg aataggcata atactgtgga
     8761 atatagagga tatttcctac aatgatcaag atgagacttg caagaaagta gagtccaaag
     8821 accatgagga aacgctcggt ttcaactgat gagagatcta gatttggaaa ctcaggatgt
     8881 agggtgacga attttttggc taaaaagcta ctataaaaga ggagataaat cccaagtaaa
     8941 ttagggatac tccataaaaa gagatagaaa cgtttgagaa gtagggtcaa aaaggtttga
     9001 gaaaagcgct cctcatcaaa gagagctagg ctgtttttta cagatggctc cgttttagaa
     9061 tctttcatga gtgtcagtgt tgcatagacg gaactggtca aaagaatagt cccgataaag
     9121 gagactagta gaggaaagag gtaggcttga agtatttggc caagtatgct gaaaaatggc
     9181 tgttctaaaa cagtcccgtg gatccgagat aagggattaa gaaaactaga taagatgacc
     9241 agcatactgg gaaggatata gaggagaaag agacgggggg tgtcagcctg aaaatgtttt
     9301 gactcctgac gaattgtttt taaatcaatt tttggatagt tcattctctt attataccat
     9361 agttcttata catagttcgt gacagttcct actttttttg ataaaatcat acagtgtgtc
     9421 cttgggcaca ctgtatgaac tgggactgtc tttcccagct tcggaggtaa aaaatgtcag
     9481 attcaccaat caaatatcgt ttgattaaga aagaaaaaca cacaggagct cgtctaggag
     9541 aaatcatcac tccccacggt acctttccga cacctatgtt tatgccagtt gggacacaag
     9601 ccactgtcaa aactcagtca cctgaagaat tgaaggagat gggttcggga attatcctat
     9661 caaacactta tcatctctgg cttcgccctg gagatgaact cattgcacgc gctggtggtc
     9721 tccacaagtt catgaattgg gaccagccta tcttgacaga tagtggtggt tttcaggttt
     9781 attctttagc agatagccgt aatatcacag aagaaggagt aacctttaaa aatcatctaa
     9841 atggttctaa gatgttccta tccccagaaa aagccatctc tattcagaat aatctgggtt
     9901 cagacatcat gatgtccttt gatgaatgtc ctcagtttta tcaaccttat gactacgtta
     9961 agaaatcgat agagcgtacc agccgttggg ctgagcgtgg tttgaaggct caccgtcgtc
    10021 cacatgacca aggtttgttt ggaattgtgc aaggtgcagg atttgaagac cttcgccgcc
    10081 aatcagctca tgatcttgtc agcatggatt tctcaggcta ctctatcggt ggtttggcag
    10141 tgggagaaac ccatgaagag atgaatgcgg tcttggactt tacaactcaa ctgctgcctg
    10201 aaaataaacc tcgttatctg atgggtgtgg gagcgccaga tagcttgatc gatggggtca
    10261 ttcgtggggt ggatatgttt gactgtgtct taccgactcg aattgctcgt aacgggactt
    10321 gtatgaccag tcaaggacgt ttggttgtga aaaatgccca gtttgctgag gactttacgc
    10381 cactggatcc tgagtgtgat tgctacacat gtaataacta tacacgcgct taccttcgtc
    10441 acctgctcaa ggctgatgaa acctttggga tccgcttgac tagctaccac aatctttact
    10501 tcttgcttaa cctgatgaag caagtgcgac aagccatcat ggatgacaat ctcttggaat
    10561 tccgtgagta ttttgtggaa aaatatggct ataataagtc aggacgtaat ttctaaaatg
    10621 gaattgatat aagctaaaaa tcctaagttt tctcttagga tttttcttct ttttttgata
    10681 gaataaagtg tacaatgaaa ggaagaataa actcgtatgc gcattaaatg gttttccttg
    10741 gttaggatta caggtttact tttggtactc ttgtatcact tctttcagac gatctttcct
    10801 ggaggatttt tcggggtaga tgtctttttc acattttcag gtttcctgat tacagctcta
    10861 ctcattgaag aattttctaa aaaccatgag attgatttga taggattttt tagaagacgc
    10921 ttttatcgga ttgtgccacc tgtggttttg atggtcttgg tgaccatgcc ttttactttc
    10981 ttggttcgcc aagactatgt tgctggaatt ggtggccaga ttgcgagcgt cttaggcttt
    11041 atgaccaact tctatgaact cctaacaggt gggagttatg aatctcagtt cattcctcat
    11101 ttgtttgttc ataattggag tttggcagtt gaggttcact actatattct ttggggattg
    11161 gcagtttggt tcttatccaa acaagctaaa tcaaatggtc agttgaaggg gatggtcttt
    11221 ctcttatctg ctgttgcctt cttgatcagt ttcttctcca tgtttattgg tagttttcta
    11281 gtgacctctt attcctctgt ttatttctcc agtttaactc atgtctatcc attctttttg
    11341 ggaagtatgt tagcaactat tgtaggcgtt cgtcagacga cttccctcgt caagcagttg
    11401 gataaaatct gggatttacg aaagactttg gtagtttttg gaggaggctt tggtttccta
    11461 gttcttttga ctttctttgt caaattcact tatctttttg cctatcttat cggcttctta
    11521 cttgccagtc ttgcagctct tgccatgatt ctggcggcgc gtgtcttaca tgaaaagaca
    11581 catcatatac aggagccgaa gattatcagc tttttagcgg atactagcta tgcggtttat
    11641 cttttccatt ggcctttcta tatcattttc tcacagttga catcaaatct tcttgctgta
    11701 ttactgactc tgatttgttc ttatggcttt gccagtctgt cattttatgt attggaacct
    11761 tggattgcag gcaagaacac acctattgtc caaacccttc gtcccctgcc ttatattcac
    11821 gcaattcttg cagcaggtac aggaatcttg accatcattg tctgcacggt gaccttgttg
    11881 gcaccacaag tgggagcgtt tgagacagac ttgactgtca atggcttgaa gcaagctgca
    11941 acaaatattg gccagaccaa ggtgatggca gaacgggcag atgcaaacag tttgggaatt
    12001 gctgatggca ctatgttaat tggtgactca gtggctttaa gggcaaatac agcactacag
    12061 acagctcttc ctggagcaca gattaacgcg caggtcagcg taacaaccaa gaccgcaaat
    12121 gaaatcatgc taaataatag ccagaataaa tttttaccta agacggtggt cattgcgact
    12181 ggggtaaata atcctgagaa ttacaaggat gactgggaca gtatcgtgaa aaatcttcct
    12241 aagggacacc atataatttt ggtgactcct tatgagggag ataagacaaa agagacctat
    12301 gccatcgttg agaaggctgc tgcctatatg agagaattgg cagagaagac accttacatt
    12361 acgatagcag attggaatca agttgcgaaa gagcatccag aaatttgggc aggaacagac
    12421 caggttcatt tcgggagtga gagtagcact atcgaagcag gagcaaaatt gtatgcagat
    12481 acgattgcca cagctttgca gacagctcaa gacaagccgg ttaaatcaaa ataacttgta
    12541 ttaaaaaaga gaagagttgg agaaatccag ctcttttaaa atatctccaa aaaataggtc
    12601 tataccattt acaaataaaa aagaaaggtt tataatgtaa ttgacataat aaattgtaga
    12661 atcaatcttt taaggaggtt aacattatgc ctaactatat taaagcggat cagtttttct
    12721 acccacacgg agttcgtcga ggtggttact tggaacttgt ggacggcaag tttgggaaac
    12781 atgtagagca gattcctgaa ggggctgagg tgattgacta tacaggttat agcattgccc
    12841 caggtcttgt ggatactcat attcatggat atgcaggtgt agatgtgatg gacaacaaca
    12901 ttgaaggtac attgcatact atgagtgaag gacttcttag taccggtgtt accagtttct
    12961 tacccacaac tttaacagcc acttatgagc aattgcttgc agtcactgaa aatcttggaa
    13021 accattataa agaagcaaca ggtgctaaga ttcgtgggat ttattatgaa ggtccatatt
    13081 tcacagaaac ttttaagggg gcacaaaatc caacttatat gagagacccg ggtgttgagg
    13141 agtttcattc ttggcaaaaa gcggcaaatg gcttgcttaa taaaattgcc cttgcaccag
    13201 aacgtgatgg ggtggaagac tttgttcgta cagttacggg cgaaggtgtg acggttgctc
    13261 ttggacattc aaacgcgact tttgatgaag ccaaaaaagc agtcgatgct ggagcgagtg
    13321 tttgggtgca tgcctacaat ggaatgcgtg ggttgactca ccgtgaattg ggtatggttg
    13381 gagccatgta ccaattgcca catacctatg cagagttgat ctgtgatggt caccacgtag
    13441 atccaaaggc ttgcgaaatt cttatcaaac aaaaaggaac agaaaacatc gctcttatca
    13501 cagactgtat gacagctggg ggattggaag acggagatta tatgttggga gaattcccag
    13561 ttgtcgttgc aaatggaact gcacgcctca aatcgacagg taacttggca ggttctatcc
    13621 tcaaactcaa agatggtttg aagaatgtgg tcgaatgggg aattgcgaat ccgcatgaag
    13681 cagtcatgat ggccagcttc aacccagcta aatccgttca catcgatgac gtctgtggcc
    13741 aaatccgtga aggctacgac gctgacttca tcgtattaga taaagatttg gaattggtag
    13801 caacctacct agatggcgta aaacgttatc aagcataaga gagaaagcag aagttagaga
    13861 ctaacttctg cttttttatg cagggtactt tactggtaaa taaaaagtta aaaaaatcac
    13921 aaaaaaagct tgaagaaaca aagaaaaagg cttataattg aactataaat attacaaata
    13981 aaaaaacgga ggagtgcttt atgaaagcct atacttatgt taaaccagga cttgcttctt
    14041 ttgttgatgt agacaaacca gttattcgca agccaacaga cgctattgtg cgtattgtaa
    14101 aaaccactat ttgtggaaca gacctccata ttatcaaagg ggatgttcct acttgccaaa
    14161 gtggtaccat tcttggccac gaagggattg ggattgttga agaagttggg gaaggagttt
    14221 ccaacttcaa aaaaggtgac aaggtcttga tttcttgcgt ctgtgcctgt ggtaaatgct
    14281 actactgtaa aaaaggaatt tatgctcact gtgaagacga agggggctgg attttcggtc
    14341 acttgattga tggtatgcag gctgaatatc tacgtgtccc tcatgcagat aatactcttt
    14401 accatactcc agaagacttg tcagatgaag ctttggttat gctgtcagac attctgccta
    14461 ctggatatga aattggtgtc ttaaaaggga aagtagaacc tggttgcagc gtagccatta
    14521 ttggttcagg tccagttgga ttggctgctc ttttaacagc ccaattctat tcaccagcta
    14581 aattgattat ggtagaccta gacgataacc gcttggaaac tgccctatca ttcggtgcga
    14641 ctcataaggt taattcttca gaccctgaaa aagccattaa agaaatttat gatttgacag
    14701 atggtcgtgg tgtggatgtc gctatcgaag ctgttggtat tcctgcaaca tttgatttct
    14761 gtcaaaagat tatcggtgta gacggaacgg ttgccaactg tggtgtgcat ggtaaaccag
    14821 ttgaattcga tttagataaa ctttggattc gcaacatcaa tgtaacaact ggtttggtat
    14881 ctacaaatac gactccacaa ttgttgaaag cgcttgaaag tcataagatt gaaccagaaa
    14941 aattggtaac tcactatttc aaactcagtg aaattgaaaa agcctacgaa gtcttcagta
    15001 aggcagcaga ccaccatgcc attaaggtca ttatcgaaaa cgatatctca gaagcctaag
    15061 tagtaaaaat atttttgtac ataagtaaat agaaattcag tcatccatca gatggctgga
    15121 ttttttatca aaaaattaag aaatgagcat atttctttcc ttgtctggcg gaattggtta
    15181 taatatacgg tacaaaggaa tgaatgaata tgtatcgtgt tatagaaatg tacggagatt
    15241 ttgaaccgtg gtggttctta gaaggttggg aagaagatat tgtagcaagt agaaaatttg
    15301 accagtatta tgatgctctc aaatactaca aaacttgctg gtttagattg gaacaagaat
    15361 cccctcttta taaaagtaga agcgacttga tgaccatttt ttgggacccg gaagaccaac
    15421 gctggtgtga tgaatgtgat gagtatttac aacaatacca ttctttggct cttttgcagg
    15481 atgagcaggt tatcccagac gaaaaactac gctcaggcta tgaaaaacaa accagtcagg
    15541 aaaggaatcg ttcttgccgt atgaaattaa aatagagaaa agtaactttt ttggagttgc
    15601 tttttttatt tttctaacgc tttgcgaata gtataggtga ggaggtaagt atggttcaag
    15661 aaattgcaca agaaatcatt cgctcggctc ggaaaaaagg ggcgcaagac atttattttg
    15721 tccccaagtt agacgcctat gagcttcata tgagggtagg agacgagcgc tgtaaaattg
    15781 gtagctatga ttttgaaaag tttgcagccg ttatcagtca ctttaagttt gtggcgggta
    15841 tgaatgtggg agaaaaaaga cgtagtcaac tgggttcctg tgattatgcc tatgaccaga
    15901 agatggcgtc tctacgttta tctactgtag gcgattatcg ggggcatgag agtttggtta
    15961 tccgtttgtt gcacgatgag gagcaggact tgcatttttg gtttcaggat attgaagaat
    16021 taggcaagca gtacaggcaa cggggactct atctttttgc tggtccggtt gggagtggta
    16081 agacgacctt gatgcatgaa ttgtccaagt cactctttaa aggacagcaa gttatgtcca
    16141 tcgaagatcc tgtcgaaatc aagcaggacg acatgcttca gttgcagttg aacgaagcaa
    16201 tcggtctaac ctatgaaaat ctaatcaaac tttccttgcg tcatcgacca gatctcttga
    16261 ttatcggaga aattcgtgac atcgagacgg cgcgtgcagt ggtcagagct agtttgacag
    16321 gtgcgacagt cttttcaacc attcacgcca agagtatccg aggtgtttat gagcgtctgc
    16381 tggagttggg tgtgagtgaa gaagaattgg cagttgttct gcaaggagtc tgctaccaga
    16441 gattaatcgg gggaggagga atcgttgact ttgcaaacag agattatcaa gaacaccaag
    16501 cagccaagtg gaatgagcaa attgaccagc ttcttaaaga tggacatatc acaagtcttc
    16561 aggctgagac ggaaaaaatt agctacagct aagcaaaaaa atatcatcac cctatttaac
    16621 aatctctttt ctagcggttt tcatctggtg gagactatct cctttttaga taggagttcc
    16681 ttgttggaca agcagtgtgt gacccagatg cgtacaggct tgtctcaggg gaaatcattc
    16741 tcagaaatga tggaaagttt gggatgttca agtaccattg tcactcagtt atctctagct
    16801 gaagttcatg gcaatcttca cctgagtttg ggaaagatag aagaatatct agacaatctg
    16861 gccaaggtca agaaaaagtt aattgaagta gcgacctatc ctttgatttt gctgggtttt
    16921 cttctcttaa ttatgctggg gctacggaat tacctgctcc cacaactgga tagtagcaat
    16981 attgccaccc gaattatcgg taatctgcca caaatttttc taggcatggt agggcttgtt
    17041 tccgtgcttg cccttttagc actaactttt tataaaagaa gttctaagat gagtgtcttt
    17101 tctatcttag cacgccttcc ctttattgga atctttgtgc agacctactt gacagcctat
    17161 tatgcacgtg aatgggggaa tatgatttca cagggaatgg agctgacgca gatttttcaa
    17221 atgatgcagg aacaaggttc ccagctcttt aaagaaatcg gtcaagatct ggctcaaacc
    17281 ctgaaaaatg gccgtgaatt ttctcagacg ataggaacct atcctttctt taggaaggaa
    17341 ttgagtctca tcatagagta tggggaagtt aagtccaagc tgggtagtga gttggaaatc
    17401 tatgctgaaa aaacttggga agcctttttt acccgagtca accgcaccat gaatttggtg
    17461 cagccactgg tttttatctt tgtggcactg attatcgttt tactttatgc ggcaatgctc
    17521 atgcccatgt atcaaaatat ggaggtaaat ttttaaaatg aaaaaaatga tgacattctt
    17581 gaaaaaagct aaggttaaag cttttacatt ggtggagatg ttggtggtct tgctgattat
    17641 cagcgtgctt ttcttgctct ttgtacctaa tctgaccaag caaaaagaag cagtcaatga
    17701 caaaggaaaa gcagctgttg ttaaggtggt ggaaagccag gcagaacttt atagcttgga
    17761 aaagaatgaa gatgctagcc taagcaagtt aaaagaagat ggacgcatca cggaagaaca
    17821 ggctaaagct tataaagaat acaatgataa aaatgtggga gcaaatcgta aagtcaatga
    17881 ttaaggcctt taccatgctg gaaagtctct tggttttggg tcttgtgagt atccttgcct
    17941 tgggcttgtc cggctctgtt cagtccactt ttgcggcggt agaggaacag attttcttta
    18001 tggagtttga agaactctat cgggaaaccc aaaaacgcag tgtagccagt cagcaaaaga
    18061 ctaatctaaa tttagatggg cagacgctta gcaatggcag tcaaaagttg acagttccta
    18121 aaggaattca ggcaccatca ggccaaagta ttacatttga ccgagctggg ggcaattcgt
    18181 ccctggctaa ggttgaattt cagaccagta aaggagcgat tcgctatcaa ttatatctag
    18241 gaaatggaaa aattaaacgc attaaggaaa caaaaaatta gggcagtgat tttactggaa
    18301 gcagtagtcg ctctagctat ctttgccagc attgcgaccc tccttttggg acaaattcaa
    18361 aaaaataggc aagaggaagc aaaaatcttg caaaaggaag aagtcttgag ggtagctaag
    18421 atggccctgc agacggggca aaatcaggta agcatcaacg gagttgagat tcaggtattt
    18481 tctagtgaaa aaggattgga ggtctaccat ggttcagaac agttgttggc aatcaaagag
    18541 ccataaggtc aaggctttta ccttgttaga atccctactt gccctcattg tcatcagtgg
    18601 gggattactc ctttttcaaa ctatgagtca gctcctcatt tcagaagttc gctaccagca
    18661 acaaagcgag caaaaggagt ggctcttgtt tgtggaccaa cttgaggcag aattagaccg
    18721 ttcgcagttc gaaaaagtag aaggcaatcg cctatacatg aagcaagatg gcaaggacat
    18781 cgccatcggt aagtcaaagt cagacgattt tcgtaaaacg aatgctcgtg gtcgaggtta
    18841 tcagcctatg gtttatggcc tcaaatcagc tcagattaca gaggacaatc aactggttca
    18901 ttttcgtttc cagtttcaaa aaggcttaga aagggagttc atctatcgtg tggaaaaaga
    18961 aaaaagttaa ggcaggtgtt ctcctctacg cagtcaccat agcagccatc tttagtcttt
    19021 tgttgcaatt ttatttgaac cgacaagtcg cccactatca agactatgct ttgaataaag
    19081 aaaaattggt tgcttttgct atggctaaac gaaccaaaga taaggttgag caagaaagtg
    19141 gggaacaggt ttttaatcta ggtcaggtaa gctatcaaaa caagaaaact ggcttagtga
    19201 cgagggttcg tacggataag agccaatatg agtttctgtt tccttcagtc aaaatcaaag
    19261 aagagaaaag agataaaaag gaagaggtag cgaccgattc aagcgaaaaa gtggagaaga
    19321 aaaaatcaga agagaagcct gaaaagaaag agaattccta gtcaattcaa ctataatgcg
    19381 ttgaatccag aatagtccac tgtagtttct agaaaattgc tggaaatgga tgttaagctc
    19441 caattcattt gtttatatct tatttcagtt tactatactt tgtgctaaat taaagatatg
    19501 aaacatgatt ttaaccacaa agcagaaact ttcgatttcc ctaaaaatat cttcctcgca
    19561 aacttggtat gtcaagcagc cgagaaacag attgatcttc tatcatacaa agaaatttta
    19621 gatttcggtg gtggcacggg tctattagcc ttgcccctaa cccctagcca agcaggctaa
    19681 gtcagtcact cttgtagaca tttctgagaa aatgttggag caagctcgtt tgaaagtgga
    19741 gcagcaagca atcaagaata tccagttttt ggagcaagat ttaccgaaaa atcccttgga
    19801 gaaagagttt gattgccttg ctgttagtcg ggttcttcat catatgcctg atttggatgc
    19861 ggctctctca ctgtttcatc aacatttgaa ggaagatggg aaactcatca ttgctgattt
    19921 taccaagaca gaagctaatc atcatggatt tgatttagct gaactggaaa acaagctaat
    19981 tgagcatggt ttttcatctg tgcatagtca gattctctat agcgctgaag acctgtttca
    20041 aggaaatcac tcagaattct ttttaatagt agcccaaaaa tcactcgcct agtcagggag
    20101 tgatttttct ataagaatgg aaaaaagaag ggaaatttga taagatagga atatggattt
    20161 tgaaaaaatt gaacaagctt atacctattt actagagaat gtccaagtca tccaaagtga
    20221 tttggcgacc aacttttatg acgccttggt ggagcaaaac agcatctatc tggatggtga
    20281 gactgagcta gaacaggtca aagacaacaa tcagaccctt aagcgtttag cactacgcaa
    20341 agaagaatgg ctcaagacct accagtttct cttgatgaag gctgggcaaa cagaaccctt
    20401 gcaggccaat caccagttta caccggatgc tattgcttta cttttggtgt ttattgtgga
    20461 agagctgttt aaagaggagg aaattactat cctcgaaatg ggttctggga tgggaatttt
    20521 gggcgctact ttcttgacct cgcttactaa aaaggtggat tatttgggaa tggaagtgga
    20581 tgatttgctg attgatttgg cagctagcat ggcagatgta attggtttgc aggctggctt
    20641 tgtccaagga gatgccgttc gtccacaaat gctcaaagaa agtgatgtgg tcatcagcga
    20701 cttgcctgtt ggctattatc ctgatgatgc cgttgcgtcg cgccatcaag ttgcttctag
    20761 tcaagaacat acttacaccc atcacttgct catggaacaa ggacttaagt acctcaagtc
    20821 agacggatac gctatttttc tagctccgag tgatttgttg accagtcctc aaagtaattt
    20881 gttgaaagtc tggttgaaag aggaggcaag tctggttgct atgattagtt tacctgaaaa
    20941 tctctttgct aatgctaaac aatctaagac tatttttatc ctacagaaga aaagtgaaat
    21001 agcagtagag ccttttgttt atccacttgc tagcttgcaa gatgcaagtg ttttaatgaa
    21061 atttaaagaa aattttcaaa aatggactca aggtactgaa atataaaata gattttgtta
    21121 taatagttga aaacgcttaa aaaggggtat catgttatga caaaaacaat tgcaatcaat
    21181 gcaggaagtt caagtttgaa atggcaatta tacttaatgc cagaagaaaa agtattggcg
    21241 aaaggtttga ttgaacgtat cggtttgaaa gattcaattt caactgtaaa atttgacggc
    21301 cgttctgaac aacaaatttt ggatattgaa aatcatacac aagctgttaa aattttattg
    21361 gatgacttga ttcgtttcga tattatcaag gcttatgacg agattacagg tgttggacat
    21421 cgtgttgttg ctggtggaga atatttcaaa gaatcaacag ttgttgaggg agatgtttta
    21481 gaaaaagttg aagagttgag tttgttggct cctctacaca acccggcaaa tgcagcaggt
    21541 gttcgtgcct tcaaggaatt gttgccagac attaccagtg tagttgtttt tgatacttcc
    21601 ttccacacaa gtatgccaga gaaagcttat cgctaccctc taccaacaaa atattacaca
    21661 gaaaacaagg ttcgtaaata cggtgctcat ggtacaagtc accagtttgt agcaggagaa
    21721 gctgcaaaac tcttgggacg tccattagaa gacttgaagt taattacctg tcatattggt
    21781 aacggaggct caattacagc tgtgaaagcc ggcaaatctg tagacacttc tatggggttc
    21841 actcctcttg gtggtattat gatgggaacg cgtacagggg atattgatcc agctatcatt
    21901 ccttatttaa tgcaatatac agaggatttt aacacaccag aagatatcag tcgtgttctt
    21961 aaccgtgaat caggtctttt gggagtttct gctaattcta gcgatatgcg cgatatagaa
    22021 gcagctgtag cagaagggaa tcacgaggct agcttggctt atgaaatgta tgttgaccgt
    22081 atccaaaaac atatcggtca gtaccttgca gtgctaaatg gagcagatgc cattgttttc
    22141 acagcaggtg tcggtgaaaa tgcagagagt ttccgtcgtg atgtaatctc agggatttcg
    22201 tggtttagtt gtgatgttga tgatgaaaag aatgtctttg gcgttacagg agacatctca
    22261 acagaggcag ctaaaatccg tgtcttggtt attccaacag atgaagaatt agtcattgcc
    22321 cgtgacgttg aacgcttgaa aaaataagtg aaactaaaaa aatattcaat acaaggagtt
    22381 gggaaagtta tttttccagc ttctttttct gatgaaattg tccaaaacct tgctatgatt
    22441 ggcttttttg aaaaatatgg tataatagta gtaatttaat agatggagtt gagttttgaa
    22501 gaaaaacttt cgtgtaaaaa gagagaaaga ttttaaggcg attttcaagg aggggacaag
    22561 ttttgctaat cgcaaatttg tggtctacca attagaaaac cagaaaaacc attttcgagt
    22621 aggtctatca gttagcaaaa aactggggaa tgccgtcact agaaatcaaa ttaagcgacg
    22681 gattcggcat attatccaga atgcaaaagg gagtctggta gaagatgtcg actttgttgt
    22741 cattgctcga aaaggagtcg aaaccttggg atacgcagag atggagaaaa atctactcca
    22801 tgtattaaaa ttatcaaaga tttaccggga aggaaatggg agtgaaaaag aaactaaagt
    22861 tgactagttt gctaggactg tctctgttaa tcatgacagc ctgtgcgact aatggggtaa
    22921 ctagcgatat tacagccgaa tcggctgatt tttggagtaa attggtttac ttctttgcgg
    22981 aaattattcg ctttttatcg tttgatatta gtatcggagt ggggattatt ctctttacgg
    23041 tcttgattcg tacagtcctc ttgccagtct ttcaggtgca aatggtggct tctaggaaaa
    23101 tgcaggaagc tcagccacgc attaaggcgc ttcgagaaca atatccaggt cgagatatgg
    23161 aaagcagaac caaactagag caggaaatgc gtaaagtatt taaagaaatg ggtgtcagac
    23221 agtcagactc tctttggccg attttgattc agatgccggt tattttggcc ctgttccaag
    23281 ccctatcaag agttgacttt ttaaagacag gtcatttctt atggattaac cttggtagtg
    23341 tggatacaac ccttgttctt ccgattttag cagcagtatt caccttttta agtacttggt
    23401 tgtccaacaa agctttgtct gagcgaaatg gcgctacgac tgcgatgatg tatgggattc
    23461 cagtcttgat ttttatcttt gcagtttatg cgccaggtgg agtcgcccta tactggacag
    23521 tgtctaatgc ttatcaagtc ttgcaaacct atttcttgaa taatccattc aagattatcg
    23581 cagagcgcga ggccgtagta caggcacaaa aagatttgga aaatagaaaa agaaaagcca
    23641 agaaaaaggc tcagaaaacg aaataaataa ggaggaatct ggtaatggta gtatttacag
    23701 gttcaactgt tgaagaagca atccagaaag gattgaaaga attagatatt ccaagaatga
    23761 aggctcatat caaagtcatt tctagggaga aaaaaggctt tcttggtcta tttggtaaaa
    23821 aaccagccca agtggatatt gaagcgatta gtgaaacgac tgttgtcaaa gcaaatcaac
    23881 aggtagtaaa aggcgttccg aaaaaaatca atgatttgaa cgagcctgtg aagacggtta
    23941 gtgaagaaac cgttgacctt ggtcatgtgg ttgatgctat taaaaaaata gaggaagaag
    24001 gtcaaggtat ttctgatgaa gtcaaggctg aaatcttaaa acatgaaaga catgccagca
    24061 ctatcttaga agaaactggt cacattgaga ttttaaatga acttcaaatc gaggaagcga
    24121 tgagggaaga agcaggcgct gatgaccttg aaactgagca agatcaaact gaaaatcaag
    24181 acttgaaaga gatgggcttg aaggtcgagc aaagttatga tattgcccag gtggctacgg
    24241 atgtgactgc ttatgttcaa acgattattg atgacatgga tgttgaggct acactttcaa
    24301 atgattataa ccgtcgtagc atcaatttgc aaattgatac taacgaacca ggtcgtatta
    24361 tcggctacca tggtaaagtc ttgaaggcct tgcaactgtt ggctcaaaat tatctttaca
    24421 actgctattc aagaaccttc tatatcacta ttaatgtcaa tgattatgtt gaacaccgtg
    24481 cagaagtctt gcagacctat gcgcaaaaat tggcgattcg tgttttagaa gaagggcgca
    24541 gtcatcaaac agatccaatg tcgaatagtg aacgcaagat tatccaccgt attatttcac
    24601 gtatggatgg cgtgaccagt tactctgaag gtgatgagcc aaatcgctat gtcgttgtag
    24661 atacagaata agtaaaatca gggttgacct gattttttgc tagctagagg aggttaaact
    24721 gatgttgaat aagataagag actatctaga cttttctggt ttgcagtacc gtagtcctga
    24781 taaagcggga gcagagcgag agaagatgct ggcgttccgc cacaaaggac aagaggcccg
    24841 aaaggctttt acagaactgg ccaaagcctt tcaagcaagc catccagaat ggcaactcca
    24901 acagactagt cagtggatga atcaggccca gcgtttgaga ccacattttt gggtttatct
    24961 acagagagac ggacaagtga cagaacctat gatggcctta cgtttgtatg ggacatctac
    25021 tgactttgga atttctttgg aagtcagttt catcgaacgt aagaaggatg agcaaacact
    25081 gggcaagcag accaaagttt tagacattcc aaccgttaaa gggatttatt atctaaccta
    25141 ctctaatggt caaagtcaac ggtgggaggc gaatgaagaa aagcgtcgta ctttacgcga
    25201 gaaggtgaga agtcaagaag ttcgaaaagt tttagtgaag gtagatgttc ctatgacaga
    25261 aaattcgtct gaagaagaaa tcgtagaagg cttattgaag tcttattcta aaattcttcc
    25321 ctattatcta gctacgagaa aataagataa tttgtaaaac atcataaatc atacagtcca
    25381 agagtgaaca gtccgctgtg taattcttgg tctttttgtt tgcgctttcg cattatataa
    25441 taaacttaca aaaacaattc aaaaggagaa caattatgga agtcgtttca agtgttctaa
    25501 attggttttc tagcaatatt ttgcagaatc ccgcattttt cgtaggttta ttggtgttga
    25561 taggatatgc acttttgaaa aaacctgccc atgacgtttt ttcagggttt gttaaagcaa
    25621 cagtagggta tatgttgctt aacgtgggtg ctggtggttt ggttacaacc tttcgtccaa
    25681 tcttagcagc tcttaactac aaattccaaa ttggtgcagc ggttatcgac ccttactttg
    25741 gacttgctgc agcaaacaac aaaattgcag cagagtttcc agattttgtt ggaactgcaa
    25801 ctacagctct attgattggt tttggaataa atatcttgct cgtagctctt cgaaagatta
    25861 cgaaggtaag aaccctcttt attactggtc acatcatggt acaacaagct gcaacagtat
    25921 ctcttatggt tctattctta gtaccacaat tgcgcaatgc ttacggtaca gcagcgattg
    25981 gtatcatctg tggactttac tgggcagtta gttcaaatat gactgttgag gcaactcaac
    26041 gcttgactgg tggtggcgga tttgcgattg gtcaccaaca gcaatttgca atctggtttg
    26101 tagataaagt agcaggacgc tttggtaaga aagaagaaag tttagacaat cttaaattac
    26161 ctaagttcct ctcaatcttc cacgatacag ttgttgcatc tgctaccttg atgctcgtat
    26221 tcttcggagc cattctttta atcttgggtc cagacattat gtctaataaa gaagtcatca
    26281 cttcaggaac tctattcaat cctgctaaac aagatttctt tatgtacatt atccaaacag
    26341 cctttacctt ctcagtttac ttgttcgttt tgatgcaagg tgtccgaatg ttcgtatctg
    26401 agttgacaaa cgccttccaa ggtatttcaa acaaattgtt gccaggttca ttcccagcgg
    26461 ttgacgttgc agcttcttat ggatttggtt ctccaaatgc tgtcctgtca ggatttatct
    26521 ttggtttgat tggtcaattg attacaattg ttttgctcat cgtctttaaa aatccgattc
    26581 ttattattac aggatttgta ccagtgttct ttgacaatgc agccattgcg gtctacgctg
    26641 ataaacgcgg cggatggaaa gcggctgtta tcctttcctt tatatcaggt gtccttcaag
    26701 ttgctctagg agctctttgt gtggcccttc tcgatttggc atcttatggt ggctaccatg
    26761 gaaatatcga ctttgaattc ccatggcttg gatttggata tatcttcaaa taccttggta
    26821 ttgttggtta tgtacttgtg tgtctcttct tgcttgttat tcctcaactt caatttgcca
    26881 aagcaaaaga taaagagaaa tattacaacg gtgaagttca agaagaagct tagtatctag
    26941 aaaaggagaa ataaaatggt taaagtatta gcagcgtgcg gaaatggaat gggttcatca
    27001 atggttatca agatgaaggt tgaaaatgct ctccgtaagc ttaatcaaac agattttaca
    27061 gtcaattcat gcagtgtcgg tgaagctaaa ggtttagcag taggatatga catcgtaatc
    27121 gcttctcttc atttgattca agaattggaa gggcgaacta atgggaagtt aattgggctt
    27181 gataacttga tggatgataa agaaatcacc gaaaaactca gtcaagcact acagtaaaag
    27241 gttggagggg gctggacaga aactgagagt tatcgtttct gtccttctcc ctctttaaat
    27301 aaaggaggca gatatgaatt taaaacaagc tttaattgac aacgactcga tccgactagg
    27361 tttagaggct aacgattgga aagaagcagt caaggtagca gtagatccct tgattgaaag
    27421 tggggcaatt ttgccagagt attacgatgc tatcattgaa tcgactgaag agtatgggcc
    27481 ttactatatc ttgatgccag gtatggctat gccccacgct agacctgaag ctggtgtgca
    27541 aagtgatgcc ttttcattga ttaccttaca aaatcctgtt gtattttcag atgggaaaga
    27601 ggtatctgtt ttgttggcac tagcagcaac aagttcaaaa attcacacaa gtgtagccat
    27661 tccacaaatt attgccctgt ttgaattaga agattctatt gcacgtttac aggcttgcca
    27721 gactaaagaa gatgtcttgg ctatgattga agaatctaag gatagccctt atctcgaagg
    27781 attggatttg gaaagttaga aagaggaata aagaaatgac aaaaagaata cctaatttac
    27841 aagttgcatt agaccattca gacttgcaag gagcgattaa agcagctgtt tctgttggtc
    27901 aggaagtaga tattatcgaa gctggaactg tttgcttgct tcaagttgga agtgaactgg
    27961 ctgaagtctt gcgtagcctt ttcccagata agattattgt ggcagacaca aaatgtgctg
    28021 atgctggtgg aacagttgct aaaaataatg cggttcgtgg agcagactgg atgacttgta
    28081 tctgttgtgc aaccatccct actatggaag cagctctaaa ggctatcaag actgaacgag
    28141 gagaacgagg cgaaatccag atcgagcttt atggcgattg gacttttgaa caagctcagc
    28201 tttggctaga tgcaggtatc tcacaagcta tttatcacca atctcgtgat gctcttcttg
    28261 ctggtgaaac ttggggtgaa aaagacctta ataaggttaa aaaactcatt gacatgggct
    28321 tccgtgtatc tgtaacaggt ggtctagatg tagatactct caaactcttt gaaggtgttg
    28381 atgtctttac ctttatcgca ggtcgtggaa ttacagaggc tgcggatcca gcaggagcag
    28441 cgcgtgcctt caaggatgaa atcaaacgaa tttgggggta aatcatggta cgtccaattg
    28501 gaatttatga aaaggcaacc ccaacacact ttacttggct agaacgttta aattttgcca
    28561 aggagttagg ctttgatttt gtcgagatgt ctattgacga acgtgacgag cgtttagcaa
    28621 gacttgactg gagtaaggaa gaacgcttgg aagttgtcaa agaaatctat gaaactggtg
    28681 ttcgtattcc ttctatctgt ttttcaggcc atcgtcgcta cccattggga tcaaaagatc
    28741 cagttctaga ggaaaaatct ctagaactca tgaaaaaatg tatcgaatta gctcaagact
    28801 tgggagttcg tacgattcaa ttagctggtt acgatgttta ctatgaggaa aagtcacccc
    28861 agacacgcca acgttttatc aaaaatttga gaaaagcctg tgactgggct gaagaagctc
    28921 aggtggtact tgctattgaa attatggatg atcctttcat cagtagcatc gaaaaatatt
    28981 tggctataga aaaagagatt gactctccct tcctctttgt atatccagat attggtaatg
    29041 tgtctgcatg gcataatgat atctatagtg agttttatct tggtcatcat gccatcgcag
    29101 ctctccatct caaggatact tatgcagtga cagaaagttc aaagggccag ttccgagatg
    29161 tacctttcgg gcaaggttgt gtcaaatggg aagaagcttt cgatatttta aaggaaacca
    29221 attataatgg acctttccta atcgaaatgt ggtctgaaaa ttgtgaaaca gtagaagaaa
    29281 cacgcgcagc cattcaagag gcgcaagctt ttctctatcc actcattaag aaagcaggtt
    29341 tgatgtaaga tgaatcaagt aatcaatgct atgcgtaaac gagtctgtga tgccaatcaa
    29401 tcattgccaa aacatggact tgtcaaattt acctggggga atgtatctga agtcaatcgc
    29461 gaactcggtg tcattgttat caaaccatca ggcgtggatt atgacgaatt gacacctgaa
    29521 aacatggtag tgactgatct agatggtaag atcctagaag gggatttaag accatcttcc
    29581 gacctcccaa ctcatgtgca attatataag acttggtcag aaattggtag tgtggttcac
    29641 acccattcga cagaagctgt tggttgggct caggcaggtc gtgatattcc tttctacgga
    29701 acaacccatg cagattattt ctacggttca atcccttgcg cccgtagttt gaccaaggac
    29761 gaagtagaag tggcctatga aaaagatact ggcctggtta tcgtagaaga gtttgaacat
    29821 cgcggactta acccggttga agtaccagga attgttgtac gcaatcacgg tccattcacc
    29881 tggggcaaaa atccagagaa tgctgtttat cactctgtcg tactagagga agtatcaaag
    29941 atgaatcgct ttacagaaca aatcaatcca agagttggac ctgctcccca gtacatacta
    30001 gaaaaacact accaacgtaa acatggacca aatgcttatt atggtcaaaa gtaagaacga
    30061 tgaaggagga gaaaaagata aatttagctc ctctttttac atttgatttt tattgagagt
    30121 aaagttggag ttgaagtaat tttgaaagat tttttagaaa tagcgcttga tatatatatg
    30181 gtaaaataaa aagaattgct gtgatatcaa tagatttggg ggatttttta atatggtact
    30241 ggataaggca agttgtgatt tgcttcaata tttgatggat caagaaacgt ccaaaacgat
    30301 tatggcgatt tcgaaagatt tgaaagagtc aagaaggaaa atttattatc acattgacaa
    30361 aatcaatgct gctctggttg acgaggcgct tcacatcatt agtattccac gaattggtat
    30421 tcacttaacg gaagagcaga gagatgcttg ttgtaaacta ttatcggaag tagattcgta
    30481 cgattatatc atgagtgcgc atgaacgtat gatgataatg ttactatgga taggtatttc
    30541 taaagaacgt attacgattg aaaaattgat agagttaaca gaggtatcta ggaatactgt
    30601 tctcaatgat ttgaatagta ttcgttatca actaactttg gaacaatatc aggtgatctt
    30661 gcaagtgagc aagtcacagg gataccacct tcatgcccac cctcttaata aaattcagta
    30721 tcttcaatcg cttctatatc atatttttat ggaagaaaat gccacttttg tatctatttt
    30781 agaagataag atgaaagaga ggttagatga tgagtgtttg ctttctgttg aaatgaacca
    30841 attttttaag gaacaggttc ctttagttga acaagattta gggaagaaaa taaaccatca
    30901 tgaaataact tttatgttgc aggttctacc ttatttgctg ttaagctgtc ataatgttga
    30961 acagtatcaa gaaagacatc aggatataga gcaagaattt tctttgataa gaaaaagaat
    31021 agagtatcag gtgtctaaga aattaggaga acggttgttt caaaagtttg aaatttcttt
    31081 gtcaggactt gaagtttctc ttgtagctgt tctcctcctc tcctatcgta aagatttgga
    31141 tattcatgca gaaagtgatg attttcggca attaaaactt gctttagaag aatttatctg
    31201 gtattttgaa tcacaaatcc gaatggagat tgagaacaag gatgatttgt tacgaaattt
    31261 gatgatccac tgtaaagcct tgttatttag aaagacttac ggtatttttt ctaaaaatcc
    31321 tctaacaaaa caaattcgat ccaagtatgg agaattattt ttagtcacta gaaaatctgc
    31381 ggaaatttta gaaggagcat ggtttattcg gctaacagac gatgatattg cctatttgac
    31441 gattcatatt ggaggatttt taaagtatac accatcgtct caaaaaaata tgaaaaaagt
    31501 ttatctcgtt tgtgatgaag gtgttgcggt ttcgagactt ttgctgaaac aatgcaaact
    31561 ttattttcca aatgagcaaa ttgacactgt atttacaaca gaacaattta agagtgtgga
    31621 agatattgca caagttgatg tagtgattac tactaatgat gatttggata gcagatttcc
    31681 gattttaagg gttaatccta tccttgaagc agaagatatt ttgaaaatgc tagactatct
    31741 taaacacaat atatttcgta atgagagcaa aagtttcagt gaaaatcttt ctagtcttat
    31801 ttcgtcttat attgtagaca gcaagttggc tagtaagttc caagaagagg ttcaaacact
    31861 tataaatcaa gaaatagtag ttcaagcttt tttggaagat atttgaagga cagtccaatg
    31921 atgaacacaa acctgtgttt ttcttggtct tttttagtgt tttgaagggt ggtatactaa
    31981 tctcaaagat aacaattata tccaaaggag gcaacatatg ccaaacgtca aagaaattac
    32041 aagagagtta tggattttag ccactttccc agagtgggga acatggttga acgaagaaat
    32101 cgaagaagaa gtcgtacctg aaggcaactt tgccatgtgg tggctaggca actgtggtac
    32161 ttggattaag acaccagctg gtgctaacgt tgtcatggac ctttggtcaa accgtggaaa
    32221 atcaaccaaa aaagtgaaag atatggttcg tgggcaccaa atggcaaata tggcaggtgt
    32281 tcgtaagttg caaccaaact tgcgtgttca gccaatggtt atcgatccat ttgctatcaa
    32341 cgaactagac tattacttag tttcacactt ccacagtgat catatcgacc catacacagc
    32401 tgcagcaatt ctcaacaatc ctaagttaga gcatgttaag tttatcggtc cttaccactg
    32461 tggacgaatc tgggaaggat ggggtgttcc aaaagaacgt atcaacgttg ttaaaccagg
    32521 tgacactatc gaattaaaag atatgaagat tcatgcagta gaatcatttg accgtacttg
    32581 cttggtaact ctcccagtga acggtgctga tgagacaggc ggtgaacttg ctggcttgac
    32641 tgttacagat gaagaaatgg ctcaaaaggc tgttaactat atctttgaaa caccaggtgg
    32701 aaccatctat catggtgcag attctcactt ctcaaactat tttgcaaaac atggtaaaga
    32761 ctttaaaatt gatgttgctt tgaataacta tggtgaaaat ccggtaggta tccaagacaa
    32821 aatgacatct atcgaccttc ttcgtatggc agaaaatctg cgtaccaaag tcattatccc
    32881 agttcactat gatatctggt ctaacttcat ggcttctact aatgagattc tagaactttg
    32941 gaaaatgcga aaagatcgct tgcaatacga tttccatcca tttatctggg aagttggcgg
    33001 taagtacact tatcctcaag atcaacactt agtagaatac catcatccac gtggttttga
    33061 tgattgtttt gaacaagact ctaacattca atttaaagct ttgctataat ataaaaatat
    33121 tctttggagg ttatccgtat gttgcatgat acggataatt ttcatataat agtaaaatag
    33181 aatgtgtgat tcaataatca cctcaaatag aaaggaaatt ctatgtcaaa tctatctgtt
    33241 aatgcaattc gttttctagg tattgacgcc attaataaag ccaactcagg tcatccaggt
    33301 gtggttatgg gagcggctcc gatggcttac agcctcttta caaaacaact tcatatcaat
    33361 ccagctcaac caaactggat taaccgcgac cgctttattc tttcagcagg tcatggttca
    33421 atgctccttt atgctcttct tcacctttct ggttttgaag atgtcagcat ggatgagatt
    33481 aagagcttcc gtcaatgggg ttcaaaaaca ccaggtcacc cagaatttgg tcatacggca
    33541 gggattgatg ctacgacagg tcctctaggg caagggattt caactgctac tggttttgct
    33601 caagcagaac gtttcttggc agccaaatat aaccgtgaag gctacaatat ctttgaccac
    33661 tatacttacg ttatctgtgg agacggagac ttgatggaag gtgtctcaag cgaggcagct
    33721 tcatatgcag gcttgcaaaa acttgataag ttggttgttc tttatgattc aaatgacatc
    33781 aacttggatg gtgagacaaa ggattccttt acagaaagtg ttcgtgaccg ttacaatgcc
    33841 tacggttggc atactgcctt ggttgaaaat ggaacagact tggaagccat ccatgctgct
    33901 atcgaaacag caaaagcttc aggcaagcca tctttgattg aagtgaagac ggttattgga
    33961 tatggttctc caaacaaaca aggaactaat gctgtacacg gcgcccctct tggagcagat
    34021 gaaactgcat caactcgcca agccctcggt tgggactacg aaccatttga aattccagaa
    34081 caagtatatg ctgatttcaa agaacatgtt gcagaccgtg gcgcatcagc ttatcaagct
    34141 tggactaaat tagttgcaga ttataaagaa gctcatccag aactggctgc agaagtagaa
    34201 gccatcatcg acggacgtga tccagtcgaa gtgactccag cagacttccc agctttagaa
    34261 aatggttttt ctcaagcaac tcgtaattca agtcaagatg ccttgaatgt tgtggcagct
    34321 aaattaccaa ccttcctagg tggatcagct gaccttgctc actcaaacat gacttatatc
    34381 aagacagatg gacttcaaga cgatgccaat cgcttgaatc gtaacattca gtttggtgtt
    34441 cgtgaatttg caatgggaac aatcttgaac gggatggccc ttcatggtgg acttcgtgta
    34501 tacggtggaa ctttcttcgt cttctctgac tatgtgaagg cagctgtccg cttgtcagcc
    34561 ttacaaggac ttcctgtgac ttatgtcttt acccatgatt caatcgcagt tggggaagat
    34621 ggtccgactc acgaaccagt tgagcattta gcaggtcttc gtgctatgcc aaatctaaat
    34681 gttttccgtc cagcagatgc gcgtgaaacg caagcagctt ggtaccttgc agtgacaagt
    34741 gagaaaacac caactgccct tgtcttgaca cgtcaaaact tgactgttga agatggaaca
    34801 gacttcgata aggttgctaa aggtgcttat gttgtatatg aaaatgcagc cgactttgat
    34861 accatcttga ttgcgacagg ttcagaggtt aatcttgctg tctcagctgc taaagaattg
    34921 gctagtcaag gcgaaaaaat ccgcgtagtc agcatgccat ctacagatgt ctttgataaa
    34981 caagatgcag cttacaagga agaaattctt ccaaatgcag tccgccgtcg tgttgcaatt
    35041 gaaatgggtg caagtcaaaa ctggtacaaa tatgttggtc tcgatggtgc cgttctaggt
    35101 attgatacct tcggagcctc tgccccagca ccaaaagtat tggcagaata tggctttact
    35161 gtagaaaatc ttgtaaaagt tgttcgaaac ttgaaataat cctaaaaatc agagcgtaag
    35221 ctctggtttt tcttaccaga aaagtaaggt acaatcttgt aaaagtagct gaaatttgat
    35281 atagtagtcc tatgtaaaag acaaaggaga agacaatgaa tccaaattat acatttttaa
    35341 tcatgcttgt aggtatgatg gccttgatgt tctttatgca acgttctcaa aagaaacaag
    35401 ctcaaaagcg tatggaaagc ttaaataaac tacaaaaagg ctatgaagtg attacaatcg
    35461 gtggacttta tggaacagtc gatgaagtag atacggagaa gggaacaata gttcttgacg
    35521 tagatggagt ttacttgact tttgaactag ctgctatcaa gacagtatta ccgctgaaag
    35581 aaacagcttc actagaaggc gcaattgaaa aataagacgg gatcacgaac tcccgttttt
    35641 ctataaaaga aaggaaatgg gatgaaaaaa ttagtctttg tctgtctggg aaatatttgc
    35701 cgtagcccta tggccgagtt tgttatgaaa tcaatgacag ataactacga aatccaaagt
    35761 cgagcaactt cctcttggga acatggcaat ccgattcata aggggactca gggaattttt
    35821 caagagtatg agattcctta tgacaagaac aagacatcgc ttcagattag taaggaagat
    35881 tttgaagcct ttgattatat tatcggaatg gacgcttcaa atatttctga cttacgtcag
    35941 atgtgtccag tagactgtca agataagatt tactcatttt catctgaaag tgttccagac
    36001 ccttggtata caggagattt tgaagaaacc tatcgacgtg ttcaagaggg ttgtcaagct
    36061 tggttagaac gtttagaaaa ggagagttaa ggtggaaaat cctacgaatt tttacgaaaa
    36121 gtatcgtgtc tatctgactc gtccacgttt agagcttttg gcagtagtta ccattgtttt
    36181 ctgtgctgta ctcgtctttt ttctaaatat tccaggaaaa ggtgtcttaa aactcgataa
    36241 tggaacgatt gtttatgatg gcagtcttgt ccgtggtaaa atgaatggtc aaggtaccat
    36301 taccttccaa aatggagacc aatatacagg tggcttcaac aatggagcct tcaacggaaa
    36361 aggtaccttt caatctaaag aaggctggac ctacgaaggt gattttgtaa atggtcaggc
    36421 tgaaggaaaa gggaaactaa caacagaaca agaagtcgtt tatgaaggaa cttttaaaca
    36481 aggcgttttt caacaaaaat aaagcctcct tatccaaagg aggtattatt agaaccacaa
    36541 ggtaagcgct tacctgtaaa tccctttctt tccaaatccc tcttccaagc aagtttgtga
    36601 aataaaaaat atttgaaata aatttcacaa actttaaaga taaaacctga taagaaaaga
    36661 aaatgagaaa agtttcacaa gagtttaaaa attctttgtg aaatgtttat gaaactgttt
    36721 acaaagttga aataatgcgt tataataaac ttgtgaaaaa attaacaaag gatatcgttc
    36781 cttgaaagct atggaggaaa atatggctga taaaaaaact gtgacaccag aggaaaagaa
    36841 actcgttgct gaaaaacacg tagatgagtt ggttcaaaaa gctctagttg cccttgaaga
    36901 aatgcgtaaa ttggatcaag agcaagttga ctacatcgtt gccaaagcat cagtagcagc
    36961 tttggatgcc cacggagaat tggctttaca tgcctttgaa gaaacaggac gtggtgtatt
    37021 tgaagataaa gcaactaaga acttgtttgc ctgtgaacac gtagtaaaca acatgcgcca
    37081 cactaagaca gttggcgtta tcgaagaaga cgatgtaaca ggattgactc ttattgctga
    37141 accagttggt gttgtttgtg gtattactcc aacaacaaac ccaacatcaa cagcgatctt
    37201 caaatcattg atttcattga agacacgtaa tccaatcgtc tttgccttcc atccatcagc
    37261 tcaagaatca tcagctcatg cagctcgtat cgtccgcgat gcagctatcg cagctggtgc
    37321 tcctgaaaac tgtgtacaat ggattactca accatctatg gaagcaacaa gtgcccttat
    37381 gaaccacgaa ggtgttgcga caatccttgc aacaggtggt aatgccatgg ttaaggcggc
    37441 ttattcatgt ggtaaaccag ctcttggggt aggtgccgga aacgttccag cttatgttga
    37501 aaaatcagca aacattcgtc aagcagcaca cgatatcgtc atgtctaaat catttgataa
    37561 cggtatggtc tgtgcatctg aacaagcagt tatcattgat aaagaaattt acgatgaatt
    37621 tgtagcagag ttcaaatctt accacactta ctttgtaaac aaaaaagaaa aagctcttct
    37681 tgaagagttc tgcttcggtg tcaaagcaaa cagcaaaaac tgtgctggtg caaaattgaa
    37741 cgctgacatc gttggtaaac cagcaacttg gattgcagaa caagcaggat ttacagttcc
    37801 agaaggaaca aacattcttg ctgcagaatg taaagaagtt ggcgaaaatg agccattgac
    37861 tcgtgaaaaa ttgtcaccag ttattgcagt tttgaaatct gaaagccgtg aagatggtat
    37921 tactaaggct cgtcaaatgg ttgaatttaa cggtcttgga cactcagcag ctatccacac
    37981 agctgacgaa gaattgacta aagaatttgg taaagctgtt aaagctattc gtgttatctg
    38041 taactcacct tctacttttg gtggtatcgg ggacgtttac aatgccttct tgccatcatt
    38101 gacacttgga tgtggttctt acggacgcaa ctcagttggg gataacgtta gtgccattaa
    38161 cctcttgaat atcaaaaaag tcggaagacg gagaaataac atgcaatgga tgaaacttcc
    38221 ttcaaaaaca tactttgaac gtgattcaat tcaatacctt caaaaatgtc gtgacgttga
    38281 acgtgtcatg atcgttactg accatgccat ggtagagctt ggtttccttg atcgtatcat
    38341 cgaacaactg gaccttcgtc gcaataaggt tgtttaccaa atctttgcgg atgtagaacc
    38401 ggatccagat atcacaactg taaaccgtgg tactgagatt atgcgtgcct tcaaaccaga
    38461 taccatcatc gcactcggtg gtgggtctcc aatggatgct gccaaagtaa tgtggctctt
    38521 ctacgagcaa ccagaagtgg acttccgtga ccttgtccaa aaattcatgg atatccgtaa
    38581 acgtgccttc aagttcccat tgcttggtaa gaagactaaa ttcatcgcga ttccaactac
    38641 atctggtaca ggatctgaag taacaccatt tgccgttatc tctgataaag caaacaaccg
    38701 taaataccca atcgctgact actcattgac accaactgtg gcaatcgtag atcctgcttt
    38761 ggtattgaca gttccaggat ttgttgctgc tgatactggt atggacgtat tgactcacgc
    38821 gacagaagca tacgtatcac aaatggctag tgactacact gatggtttag cacttcaagc
    38881 cattaaattg gtctttgaaa atctcgaaag ctcagttaag aatgcagact tccactcacg
    38941 tgagaaaatg cataacgctt caacaatcgc tggtatggcc tttgccaatg ccttcctagg
    39001 tatttctcac tcaatggccc ataagattgg tgcgcaattc cacacaatcc acggtcgtac
    39061 aaatgctatc ttgcttccat acgttatccg ttacaacggt acacgtccag ctaagacagc
    39121 aacatggcct aagtacaact actaccgtgc agatgaaaaa taccaagata tcgcacgcat
    39181 gcttggactt ccagcttcta ctccagaaga aggggttgaa tcttacgcaa aagctgtcta
    39241 cgaactcggt gaacgtattg ggatccaaat gaattttaga gaccaaggaa ttgacgaaaa
    39301 agaatggaaa gaacattctc gtgaattagc cttcctggct tatgaagacc aatgttcacc
    39361 agctaaccca cgtcttccaa tggtagacca tatgcaagaa atcatcgaag atgcatacta
    39421 tggctacaaa gaaagaccag gacgccgtaa ataattgttt atcagtctag aagcaagaca
    39481 aaaactcaat ttgagggaaa gatccagtaa tttttctatg ataaaaggca tcctatcaag
    39541 gtttttgaac acctgatagg atgccttttt atgatattga ggcctttttg ccctttttga
    39601 aaaactagaa tagaaacaaa atatataata gattgaaact agagtagtac acatctgctt
    39661 ctaaaacatt gttagaattc
//
LOCUS       DBERDS010000016        39432 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.016, whole genome shotgun sequence.
ACCESSION   DBERDS010000016 DBERDS010000000
VERSION     DBERDS010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.016"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..261
                     /locus_tag="ACL73E_000945"
     CDS             <1..261
                     /locus_tag="ACL73E_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGS0800936.1"
                     /translation="TDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNS
                     SSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            299..604
                     /locus_tag="ACL73E_000946"
     CDS             299..604
                     /locus_tag="ACL73E_000946"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0800937.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            652..2127
                     /locus_tag="ACL73E_000947"
     CDS             652..2127
                     /locus_tag="ACL73E_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGS0800938.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNTAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYATKAK"
     gene            2432..9133
                     /gene="bgaA"
                     /locus_tag="ACL73E_000948"
     CDS             2432..9133
                     /gene="bgaA"
                     /locus_tag="ACL73E_000948"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGS0800939.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEALKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLQKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIINTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRAIIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGATGQITLTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9443..9820)
                     /locus_tag="ACL73E_000949"
     CDS             complement(9443..9820)
                     /locus_tag="ACL73E_000949"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0800940.1"
                     /translation="MFDKKQKRGYKESAKNLANWHYNDKEDSYTHPDGWYYRFHHTKH
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKI
                     DVEPVFGQIKASLGYKRCNLRGK"
     gene            complement(9985..10230)
                     /locus_tag="ACL73E_000950"
     CDS             complement(9985..10230)
                     /locus_tag="ACL73E_000950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800941.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEDCHFHAF
                     YHAFDRLSYHLKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(10442..10801)
                     /locus_tag="ACL73E_000951"
     CDS             complement(10442..10801)
                     /locus_tag="ACL73E_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGS0800942.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10893..11849
                     /locus_tag="ACL73E_000952"
                     /pseudo
     CDS             10893..11849
                     /locus_tag="ACL73E_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11833..12390
                     /locus_tag="ACL73E_000953"
     CDS             11833..12390
                     /locus_tag="ACL73E_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0800943.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12383..12637
                     /locus_tag="ACL73E_000954"
     CDS             12383..12637
                     /locus_tag="ACL73E_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800944.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12649..14703
                     /locus_tag="ACL73E_000955"
     CDS             12649..14703
                     /locus_tag="ACL73E_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGS0800945.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLIWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHSFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14887..15747
                     /locus_tag="ACL73E_000956"
     CDS             14887..15747
                     /locus_tag="ACL73E_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGS0800946.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15958..16668
                     /gene="ccdA2"
                     /locus_tag="ACL73E_000957"
     CDS             15958..16668
                     /gene="ccdA2"
                     /locus_tag="ACL73E_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS0800947.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16688..17254
                     /locus_tag="ACL73E_000958"
     CDS             16688..17254
                     /locus_tag="ACL73E_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGS0800948.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            17265..18377
                     /gene="msrB"
                     /locus_tag="ACL73E_000959"
     CDS             17265..18377
                     /gene="msrB"
                     /locus_tag="ACL73E_000959"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS0800949.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKTVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18645..19382
                     /locus_tag="ACL73E_000960"
     CDS             18645..19382
                     /locus_tag="ACL73E_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGS0800950.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            19379..21070
                     /locus_tag="ACL73E_000961"
     CDS             19379..21070
                     /locus_tag="ACL73E_000961"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0800951.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSAGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            21186..21749
                     /locus_tag="ACL73E_000962"
     CDS             21186..21749
                     /locus_tag="ACL73E_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGS0800952.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            21771..27434
                     /locus_tag="ACL73E_000963"
     CDS             21771..27434
                     /locus_tag="ACL73E_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS0800953.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDPTKYTDEET
                     VLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPIEGTTVETR
                     EEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAPTITETVIE
                     KPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSIKVALKDNT
                     GTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKEVQLDLKKV
                     EIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLAITNIEEVT
                     EEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDLVDAMQKNP
                     NGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFDRVEGGSIK
                     NINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDKLDDAGIMT
                     NVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIVGHLAHDFN
                     PRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKRGDIFFGSN
                     DMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMGITADTFEV
                     TEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQGNKLTTDS
                     PLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVKQVKEYSVA
                     ELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVNAIKNLYLE
                     ESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGLTYLNRYYG
                     VKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFREVVAKNTLS
                     GNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYRLYEGLNNG
                     QHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRETFKSEINKRAKEQVN
                     YLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPDYAPIREFF
                     GRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETTHVNDRMAY
                     LGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQWYNPDPTKL
                     QTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRPMDRNKLSG
                     PHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTAYVNVNMMA
                     GIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKENNGLLGDDF
                     IIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKTMFDEAVTK
                     DLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            27503..29224
                     /gene="pabB"
                     /locus_tag="ACL73E_000964"
     CDS             27503..29224
                     /gene="pabB"
                     /locus_tag="ACL73E_000964"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGS0800954.1"
                     /translation="MHRKTVIDFRTLGERYTFTKPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            29225..29842
                     /locus_tag="ACL73E_000965"
     CDS             29225..29842
                     /locus_tag="ACL73E_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0800955.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSRCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            29892..30890
                     /locus_tag="ACL73E_000966"
     CDS             29892..30890
                     /locus_tag="ACL73E_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGS0800956.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            31017..31976
                     /locus_tag="ACL73E_000967"
     CDS             31017..31976
                     /locus_tag="ACL73E_000967"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGS0800957.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            32073..32912
                     /locus_tag="ACL73E_000968"
     CDS             32073..32912
                     /locus_tag="ACL73E_000968"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGS0800958.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(32960..33130)
                     /locus_tag="ACL73E_000969"
     CDS             complement(32960..33130)
                     /locus_tag="ACL73E_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGS0800959.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            33251..34135
                     /gene="miaA"
                     /locus_tag="ACL73E_000970"
     CDS             33251..34135
                     /gene="miaA"
                     /locus_tag="ACL73E_000970"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGS0800960.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            34128..35366
                     /gene="hflX"
                     /locus_tag="ACL73E_000971"
     CDS             34128..35366
                     /gene="hflX"
                     /locus_tag="ACL73E_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGS0800961.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            35359..35982
                     /locus_tag="ACL73E_000972"
     CDS             35359..35982
                     /locus_tag="ACL73E_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGS0800962.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLKEAAAFSGKRYFRSENRTAMLYID"
     gene            35997..36926
                     /gene="rnz"
                     /locus_tag="ACL73E_000973"
     CDS             35997..36926
                     /gene="rnz"
                     /locus_tag="ACL73E_000973"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGS0800963.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAKKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKDDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            36947..37702
                     /locus_tag="ACL73E_000974"
     CDS             36947..37702
                     /locus_tag="ACL73E_000974"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS0800964.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(37756..38664)
                     /locus_tag="ACL73E_000975"
     CDS             complement(37756..38664)
                     /locus_tag="ACL73E_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS0800965.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            38728..38997
                     /locus_tag="ACL73E_000976"
     CDS             38728..38997
                     /locus_tag="ACL73E_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGS0800966.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            38997..39377
                     /locus_tag="ACL73E_000977"
     CDS             38997..39377
                     /locus_tag="ACL73E_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGS0800967.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
BASE COUNT        12104 a         7367 c         8775 g        11186 t
ORIGIN      
        1 acagatattg ttcataatct agctgagaaa gtggtggttg ttcgattaga aaaaccagta
       61 acttttcaca atatgatagc tcctgataag gaagtagaag tatccctact cttctttatt
      121 attaacaatt caagttcaag tcaaacaaat attctggctc agttgatgga ctttttcaca
      181 ggaaatggac atcttgaaga cctatcaaaa atttccgaac cagaaaaact ttatgcttac
      241 attgctgaag caaccgctta atcttgtcta ttaaaaaata aaatcggagg aaatccaaat
      301 gattaaaatt cttgctgcct gcggtgcagg tgttaactca agtcaccaaa ttaaaagtgc
      361 tctagaagaa gaactttcaa accgtggtta tgatgttcac tgtgatgcag tcatggtgaa
      421 agatgtaaac gaagacctta tgaaaggtta cgatatcttt acaccaatcg ctgcaacaga
      481 ccttggtttt gaaccaggta tcccagttat cgaagctggg ccaatcttat tccgtatccc
      541 agcaatgagc gctccagtat ttgacaatat tgaagcagct attaaagaac acggattaag
      601 ctaattctaa tttgttaaca ttcatataac ataaaaaagg gaggaactgt tatggatgca
      661 atctttgacc taatcggaaa ggttttcaat cccatcttag aaatgggtgg acctgtcatc
      721 atgttgatca ttttgacagt attggcttta ctttttggag tgaaattctc caaagcgctt
      781 gaaggtggta tcaaacttgc catcgctctt acaggtatcg gtgctatcat cggtatgcta
      841 aacactgctt tctcagcatc acttgcaaaa ttcgttgaaa acactggtat ccaattgagt
      901 attaccgacg ttggttgggc accactcgca acaatcactt ggggttctgc ttggacacta
      961 tacttcttgc tcatcatgtt gattgtcaac gtagtgatgc ttgctatgaa gaaaaccgat
     1021 acacttgatg tcgatatctt tgatatctgg cacttgtcta tcacaggtct cttgattaaa
     1081 tggtatgctg ataacaatgg tgtgagtcaa ggggtttcac tctttattgc tacagcagct
     1141 atcgtccttg tcggtgtgtt gaaaattatc aactctgact tgatgaaacc tacatttgat
     1201 gaccttctta acgccccaag ttcatcacca atgacatcaa ctcacatgaa ctacatgatg
     1261 aacccagtta tcatggtttt ggataagatt tttgaaaaat tcttcccagg ccttgataaa
     1321 tatgactttg atgctgctaa attgaacaag aaaatcggtt tctggggatc taaattcttc
     1381 atcggtttca tccttggtat cgttatcggt attatgggaa ctccacatcc aattgcaggt
     1441 gttgcagatg cagataaatg gcgtcttgtt atcaaaggat ggttgtctct tggtttgact
     1501 gccggtgtat ctttggaact cttctcactt atcggttcat ggttcatcgc agccgtagaa
     1561 ccactatcac aaggtattac aaacgttgct actaaacgtc ttcaaggacg taaattcaat
     1621 atcggtcttg actggccatt catcgctggt cgtgctgaaa tctgggcttg tgccaacgta
     1681 cttgcaccaa tcatgttgat tgaagcagtg cttctttcaa aagttggaaa tggtatcttg
     1741 ccacttgcag gtatcatcgc tatgggtgtt actccagctc tcttggttgt aactcgtggt
     1801 aaattgctcc gtatgattat cttcggaaca ctcttgttgc cactcttcct tctttcaggt
     1861 acacttattg caccatttgc aacagaactt gctaaaggtg taggtgcctt cccagaaggt
     1921 gtgagccaaa ctcaattgat tactcactct actcttgaag gaccaatcga aaaacttctt
     1981 ggttggacaa ttggtaacac tacaactggt gatatcaaag caatccttgg tgcagtagtc
     2041 ttccttgtat tctatatcgg tatctttgct tggtacagaa aacaaatgat caaacgtaac
     2101 gaagagtacg caacaaaagc aaaataatgc gctcctataa aatataaact taatgaaaat
     2161 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cacagttttg aggttgtaga
     2221 taagactgac gaagtcagct caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt
     2281 cagtaatcat atctacggca aggcgacact gacgaagttt gaattggatt ttcgcagagt
     2341 gtaaattgtt gaaactaggt tgtcatacca tgtataccac ttgggctttg gtagtagcta
     2401 actgcactaa atataatata aggaggtttt tatggggaaa ggccattgga atcggaaaag
     2461 agtttatagc attcgtaagt ttgctgtggg agcttgctca gtaatgattg ggacttgtgc
     2521 agttctatta ggaggaaata tagctggaga atctgtagtt tatgcggatg aaacacttat
     2581 tactcatact gctgagaaac ctaaagagga aaaaatgata gtagaagaaa aggctgataa
     2641 agctttggaa actaaaaatg tagttgaaag gacagaacaa agtgaaccta gttcaactga
     2701 ggctattgca tctgagaaga aagaagatga agccgtaact ccaaaagagg aaaaagtgtc
     2761 tgctaaactg gaagaaaaag ctccaaggat agaatcacaa gcttcaagtc aagaaaaacc
     2821 gctcaaggaa gatgctaaag ctgtaacaaa tgaagaaatg aatcaaatga ttgaagacag
     2881 gaaagtggat tttaatcaaa attggtactt taaactcaat gcaaattcta aggaagccct
     2941 taaacctgat gcagacgtat ctacgtggaa aaaattagat ttaccgtatg actggagtat
     3001 ctttaacgat ttcgatcatg aatctcctgc acaaaatgaa ggtggacagc tcaacggtgg
     3061 ggaagcttgg tatcgcaaga ctttcaaact agatgaaaaa gacctcaaga aaaatgttcg
     3121 ccttactttt gatggcgtct acatggattc tcaagtttat gtcaatggtc agttagtggg
     3181 gcattatcca aatggttata accagttctc atatgatatc accaaatacc ttcaaaaaga
     3241 tggtcgtgag aatgtgattg ctgtccatgc agtcaacaaa cagccaagta gccgttggta
     3301 ttcaggaagt ggtatctatc gtgatgtgac tttacaagtg acagataagg tgcatgttga
     3361 gaaaaatggg acaactattt taacaccaaa acttgaagaa caacaacatg gcaaggttga
     3421 aactcatgtg accagcaaaa tcatcaatac ggacgacaaa gaccatgaac ttgtagccga
     3481 atatcaaatc gttgaacgag gtggtcatgc tgtaacaggc ttagttcgta cagcgagtcg
     3541 taccttaaaa gcacatgaat caacaagcct agatgcgatt ttagaagttg aaagaccaaa
     3601 actctggacc gttttaaatg acaaacctgc cttgtacgaa ttgattacgc gtgtttaccg
     3661 tgacggtcaa ttggttgatg ctaagaagga tttgtttggt taccgttact atcactggac
     3721 tccaaatgaa ggtttctctt tgaatggtga acgtattaaa ttccatggag tatccttgca
     3781 ccacgaccat ggggcgcttg gagcagaaga aaactataaa gcagaatatc gccgtctcaa
     3841 acaaatgaag gagatgggag ttaactccat ccgtacaacc cacaaccctg ctagtgagca
     3901 aaccttgcaa atcgcagcag aactaggttt actcgttcag gaagaggctt ttgatacttg
     3961 gtatggtggc aagaaacctt atgactatgg acgttttttt gaaaaagatg ccactcaccc
     4021 agaagctcga aaaggtgaaa aatggtctga ttttgaccta cgtaccatgg tcgaaagagg
     4081 caaaaacaac cctgctatct tcatgtggtc aattggtaat gaaataggtg aagctaatgg
     4141 tgatgcccac tctttagcaa ctgttaaacg tttggtcaag gttatcaagg atgttgataa
     4201 gactcgctat gttaccatgg gagcagataa attccgtttc ggtaatggta gcggagggca
     4261 tgagaaaatt gctgatgaac tcgatgctgt tggatttaac tattctgaag ataattacaa
     4321 agcccttaga gctaagcatc caaaatggtt gatttatgga tcagaaacat cttcagctac
     4381 ccgtacacgt ggaagttact atcgccctga acgtgaattg aaacatagca atggacctga
     4441 gcgtaattat gaacagtctg actatgggaa tgatcgtgtg ggttggggga aaacagcaac
     4501 cgcttcatgg acttttgacc gtgacaacgc tggctatgct ggacagttta tctggacagg
     4561 tacggactat attggtgaac ctacaccatg gcacaaccaa aatcaaactc ctgttaagag
     4621 ctcttacttt ggtatcgtag atacagccgg cattccaaaa catgacttct atctctacca
     4681 aagccaatgg gtttctgtta agaagaaacc gatggtacac cttcttcctc actggaactg
     4741 ggaaaacaaa gaattagcat ccaaagtagc tgactcagaa ggtaagattc cagttcgtgc
     4801 ttattcgaat gcttctagtg tagaattgtt cttgaatgga aaatctcttg gtcttaagac
     4861 tttcaataaa aaacaaacca gcgatgggcg gacttaccaa gaaggtgcaa atgctaatga
     4921 actttatctt gaatggaaag ttgcctatca accaggtacc ttggaagcaa ttgctcgtga
     4981 tgaatctggc aaggaaattg ctcgagataa gattacgact gctggtaagc cagcggcagt
     5041 tcgtcttatt aaggaagacc atgcgattgc agcagatgga aaagacttga cttacatcta
     5101 ctatgaaatt gttgacagcc aggggaatgt ggttccaact gctaataatc tggttcgctt
     5161 ccaattgcat ggccaaggtc aactggtcgg tgtagataac ggagaacaag ccagccgtga
     5221 acgctataag gcgcaagcag atggttcttg gattcgtaaa gcatttaatg gtaaaggtgt
     5281 tgccattgtc aaatcaactg aacaagcagg gaaattcacc cttactgccc actctgatct
     5341 cttgaaatcg aaccaagtca ctgtctttac tggtaagaaa gaaggacaag aaaagactgt
     5401 tttggggaca gaggtgccaa aagtacagac cattattgga gaggcacctg aaatgcctac
     5461 cactgttccg tttgtataca gtgatggtag ccgtgcagaa cgtcctgtaa cctggtcttc
     5521 agtagatgtg agcaagcctg gtattgtaac ggtgaaaggt atggctgacg gacgagaagt
     5581 agaagctcgt gtagaagtga ttgctcttaa atcagagcta ccagttgtga aacgtattgc
     5641 tccaaatact gacttgaatt ctgtagacaa atctgtttcc tatgttttga ctgatggaag
     5701 tgtacaagag tacgaagtag atagctggga gattgccgaa gaagataaag ctaagttagc
     5761 aattccaggt tctcgtattc aagcgaccgg ttatttagaa ggtcaaccaa ttcatgcaac
     5821 ccttgtggta gaagaaggca atcctgcagc acctgtagtg ccaactgtta ctgttggagg
     5881 tgaagcagta acaggtctta ctagtcgaca accaatgcaa tatcgtactc tatcttatgg
     5941 tgcccaattg ccagaagtca cagcaagtgc tgaaaatgct gatgtgacag ttcttcaagc
     6001 aagcgcagca aacggcatgc gtgcgatcat ctttattcag cctaaagatg gtggccctct
     6061 tcaaacctat gcaattcaat tccttgaaga agcgccaaaa attgctcact tgagcttgca
     6121 agtggaaaaa gctgacagtc tcaaagaaga ccaaactgtc aaattgtcgg ttcgagctca
     6181 ctatcaagat ggaacgcaag ctgtattacc agctgataaa gtaaccttct ctacaagtgg
     6241 tgaaggggaa gtcgcaattc gtaaaggaat gcttgagttg cataagccag gagcagtcac
     6301 tctcaaagcg gaatatgagg gagctacagg tcaaatcact ctcactatcc aagccaatac
     6361 tgagaagaag attgcgcaat ctatccgtcc tgtaaatgta gtcacagatt tgcatcaaaa
     6421 acctactctt ccaacaacag taacggttga gtatgacaaa ggtttcccta aagctcacaa
     6481 agtcacttgg caagctattc cgaaagaaaa actagactct tatcaaacat ttgaagtact
     6541 aggtaaagtt gaaggaattg accttgaagc gcgtgcaaaa gtctctgtag aaggtatcgt
     6601 ttcagttgaa gaagtcagtg tgacaactcc aatcgcagaa gcaccacaat taccagaaag
     6661 cgttcggaca tatgattcaa atggtcacgt ttcatcagct aaggttgcat gggatgcgat
     6721 tcgtatagag caatacgcta aggaaggtgt ctttacagtt aatggtcgct tagaaggtac
     6781 tcaattaaca actaaacttc atgttcgcgt atctgctcaa actgagcaag gtgcaaacat
     6841 ttctgaccaa tggaccggtt cagaattgcc acttgccttt gcttcagatt caaatccaag
     6901 cgacccagtt tcaaatgtta atgacaagct catttcctac aataaccaac cagccaatcg
     6961 ttggacaaac tggaatcgta gtaatccaga agcttcagtc ggtgttctgt ttggagattc
     7021 aggtatcttg agcaaacgct ccgttgataa tctaagtgtc ggattccacg aagaccatgg
     7081 agttggtgca ccgaagtctt atgtgattga gtattatgtt ggtaagactg tcccaacagc
     7141 tcctaaaaac cctagttttg ttggtaatga ggaccatgtc tttaatgatt ctgccaactg
     7201 gaaaccagtt actaatctaa aagcccctgc tcaactcaag gctggagaaa tgaaccactt
     7261 tagctttgat aaagttgaaa cctatgctat tcgtattcgc atggttaaag cagataacaa
     7321 gcgtggaacg tctatcacag aggtacaaat ctttgcgaaa caagttgcgg cagccaaaca
     7381 aggacaaaca agaatccaag ttgacggcaa agacttagca aacttcaacc ctgatttgac
     7441 agactactac cttgagtctg tagatggaaa agttccggca gtcacagcaa atgttagcaa
     7501 caatggtctc gctaccgtcg ttccaagcgt tcgtgaaggt gagccagttc gtgtcatcgc
     7561 gaaagctgaa aatggcgaca tcttaggaga ataccgtctg cacttcacta aggataagaa
     7621 cttactttct cataaaccag ttgctgcggt taaacaagct cgcttgctac aagtaggtca
     7681 agcacttgaa ttgccgacta aggttccagt ttacttcaca ggtaaagacg gctacgaaac
     7741 aaaagatttg tcagttgaat gggaagaagt tccagcagaa aatctgacaa aagcaggtca
     7801 atttaccgtt cgaggccatg tccttggtag tgatcttgtt gctgaggtca ctgtacgagt
     7861 gacagacaaa ctaggcgaag ctctttcaga taaccctaac tatgatgaaa acagtaacca
     7921 ggcctttgct tcagcaacca atgatattga caaaaactct catgaccgcg ttgactatct
     7981 caatgacgga gatcattcag aaaatcgtcg ttggacaaac tggtctccaa caccatcttc
     8041 taatccagaa gtatcagcgg gtgtgatctt ccgtgaaaat ggtaagattg tagaacggac
     8101 tgttgcgcaa gccaaacttc acttctttgc agatagtggt acggatgcac caactaaact
     8161 cgttttagaa cgctatgtcg gtccagagtt tgaagtgcca acctactatt caaactacca
     8221 agcctacgac gcagaccatc cattcaacaa tccagaaaat tgggaagctg tgccttatcg
     8281 tgcggataaa gacatcgcag ctggtgatga aatcaacgta acatttaaag ctgtcaaagc
     8341 caaagctatg agatggcgta tggagcgtaa agcagataag agcggtgttg cgatgattga
     8401 gatgaccttc cttgcaccaa gtgaattgcc tcaagaaagc acgcaatcga agattcttgt
     8461 agatggaaaa gaacttgctg atttcgctga aaatcgtcaa gactatcaaa ttacctataa
     8521 aggtcaacgg ccaaaagtct cagttgaaga aaacaatcaa gtagcttcaa ctgtggtaga
     8581 tagtggagaa gatagccttc cagtacttgt tcgcctcgtt tcagaaagtg gaaaacaagt
     8641 caaggaatac cgtatccact tgactaagga aaaaccagtt tctgagaaga cagttgctgc
     8701 tgtacaagaa gatcttccaa aactcgaatt tgttgaaaaa gatttggcct acaagacagt
     8761 tgagaaaaaa gattcaacac tgtatctagg tgaaactcgt gtagaacaag aaggaaaaac
     8821 tggtaaagaa cgtatcttta cagcgattaa tcctgatgga agtaaggaag aaaaactccg
     8881 tgaagtggta gaagctccga cagaccgcat cgtcttggtt ggaaccaaac cagtagctca
     8941 agaagctaaa aaaccacaag tgtcagaaaa agcagataca aaaccaattg attcaagtga
     9001 agctagtcaa actaataaag cccagttacc aaatacaggt agtgcgtcaa gccaagcagc
     9061 agtagcagca ggtttagctc ttctaggttt gagtgcagga ttagtagtta ctaaaggtaa
     9121 aaaagaagac tagaaatttt gataccttct ttatcattaa agaccaaaga aaaactcttg
     9181 tcctaaatag aagataaaga gtctggaaca aaatagttct caaccacaaa aaagctagat
     9241 atttccaatt gtggaactct agctttttaa ttttgagtca ttctcttatt gtatagtgga
     9301 ttgaaactag aatagtacac ttctacttct aaaacattgt tagaaatcga tttgactgtc
     9361 cttatcgatt tgtcctgttc ttatttcatt ttactatatt ttaggaggtt attggccata
     9421 agtaccaatc ccatgtcaat tctcacttgc ccctcagatt acatctcttg taacccaaag
     9481 aagcctttat ctgcccaaag acaggttcca catcaatctt gcgttgagcg aaaatctgtc
     9541 taccttgggg agataaaagc gcctgacatt ctttagcttt caagttttga tagcgttcgt
     9601 tcatatatag tcccttttga ggggctgatt caggttcgtc ggcgtagtaa accttgattt
     9661 cctgttgaaa gtctgtctgt gttttctgat gtttggtatg gtgaaaacga taataccagc
     9721 catcaggatg tgtgtagcta tcctccttgt cattatagtg ccaattcgct aagtttttag
     9781 ctgactcttt ataccctctc ttttgtttct tatcaaacat ggcatattta atcaggaggg
     9841 gagtgatttc ttcttgaaaa tagacttgta tctgttcttg aagtttggcg gagaatttct
     9901 ctgtcgtttt cttccacaca aaactatact tgttggcatt ggcttcaatc ttagttccgt
     9961 caataaacaa acaatctaag gtcactaact cttccatttt tcaatttttc gaccagagaa
    10021 aatcccttgt gaataggcaa atagaagagt agatacaagc attttaaggt gataagacag
    10081 gcgatcaaag gcatgataga aggcgtggaa atgacaatcc tccaaggtat tcaccacttt
    10141 ttcaatagta aaaacgagat ggtcttgtgg caagaaggaa ctgatttcta gtggtaaagt
    10201 tgtttgattt gtgttatagt gaatatgcat gggatagcct ttctaaatgg tttattgggc
    10261 aattctattt taccaagact atcgtaacca tgcaaaaaaa gcaacggcaa atccgttgct
    10321 ttttttggag ataagagact attgtcccag actcttttct ttgtataaaa ttgtatagtg
    10381 ttattgtcta tactattttg tagagaaaga aaaaatccct agaaaatgct tagggattcg
    10441 actatttcat taagaacaat tcaacaatca tttctacata catgataagg gttaataaga
    10501 atcctgcacg ccagaagaat ttgatgaatt taggatagta aaagctgcgt tttttcaaaa
    10561 ggaagaaaaa gacgagaata atggctagga tcgagagggc tagccccagt ctagggagga
    10621 aattatgggt aaaggtttta gctgtaatca ggtaatattc aaataccaag accggaaaag
    10681 ccaaatccgc aaagtttcgt cctagttttt ttaatctaaa aagtttggtt aggataatgc
    10741 agacgactaa ggtcagtatc aataataaaa tagatgctaa tttcattaaa atcataccca
    10801 tattgtatca taaaaaaagg ctaatggaaa cgagaaacag aggaatttat aggaaagtca
    10861 ggcttttgag attgtgggtg atttttgtta taatgaaagt catgaaatct tataatacct
    10921 tgaatgatta ttatcgaaaa ttctttggag aaaagacttt taaagtccct attgatgcgg
    10981 gatttgactg tcccaatcgt gatggaactg tggctcatgg aggctgtact ttttgtacgg
    11041 tttcaggttc tggagatgct attgtagccc cagatgcgcc tatccgtgag caattttata
    11101 aggaaattga ctttatgcac cgtaagtggc cggatgttca gaagtatctg gtttattttc
    11161 aaaattttac caacacccat gaaaaggtgg aagttattcg agagcgttat gaacaggcta
    11221 tcaatgagcc aggtgtggta ggtatcaata ttggaacgcg cccagactgt ttaccagacg
    11281 aaaccatcga atatttggct gagttatcgg agtgcatgca tgtgacggtt gaattgggct
    11341 tgcagaccac ttatgaagca acctctgacc tgattaaccg tgtgcattct tatgaattgt
    11401 aggtggaaac ggtcaagcgt ttgagaaagt atcccaagat tgagattgtt tcccatttga
    11461 tcaatggctt gcctggtgaa acccatgaga tgatggttga aaatgtccgc cgttgtgtca
    11521 cggataacga tattcaaggg attaaactgc atttgctcca tcttatgaca aatactcgta
    11581 tgcaacgaga ttaccatgag ggacgtttac aattgatgag tcaggacgaa tatgtcaggg
    11641 tcatctgtga ccaactggaa attattccca aacatatcgt catccatcga attacaggag
    11701 atgcgcctag ggatatgctg attggtccta tgtggagcct caaaaaatgg gaagtcctca
    11761 acagcattga gatggagatg cgacgtcgtg gaagtgttca aggatgcaag gctgtaaaac
    11821 aggagtttga aaatgaaaag accacttgag atggcacatg attttttggc tgaggtcgtg
    11881 acaaaagagg atgtcgtagt ggatgcgact atgggaaatg gtcatgacac gcttttttta
    11941 gccaagctag ccaagcaagt ctatgccttt gatattcaga agcaagcctt ggaaaagacc
    12001 caagagcgtt tgcatcaggc tggcttgaca aatgcccagt taatcttgca aggccatgag
    12061 acactggacc agtttgtgac aaaagctaag gcagggattt ttaatctggg ctatttgccg
    12121 tcagctgata agtctgtcat cacccgaccg cagacaacga ttgaggcatt agaaaagcta
    12181 tgtggcttac ttgtcaaagg tggacgaatt gctattatga tttactatgg tcatgaagga
    12241 ggcgacctcg agagagatgc tgtcttggat tttgtgatcc agttgaacca acaagagtac
    12301 acagctgcca tttaccgaac tttaaaccaa gtcaacaacc cgccgttttt agtgatgatt
    12361 gaaaaattag agagatacag acatggataa acaataccta cacgaaaagc tggatgccat
    12421 gcgccagaat tttgttgaat caactcacca cgaacgagcg gtgggcgtgc tagaccaagc
    12481 gcatatgagc aaaaaaatgc ttaaaatcaa gaaaaaatta gttgctcttg aaatggaacg
    12541 gtgccagaga aaaattgagc acaaagactg ttccaagatt gaccaaaaaa tcaaagagca
    12601 gaaggagata tttgaatcct gttgtaaaaa agattaagga ggacgtgcgt ggaattactg
    12661 atttacctca tcctattttt actggttttg attgtctcaa gtacaaccaa taagctccta
    12721 ccctttttgc ctctcccttt ggtgcagatt cttttgggaa ttgtgattgg tctcttttta
    12781 cccaatactg actttcatct taatacggag ttgtttttgg ccctggttat cggacccttg
    12841 cttttccgag aggctgaaga agcagatgtt acggctattt taaaacactg gcgaatcatt
    12901 gtttatctca tatttccagt gatttttatc tcgaccctga gtttgggtgg cttggcccat
    12961 cttatttggt tcagccttcc cttggcagct tgcttggctg ttggggcagc ccttggtcct
    13021 acggacttgg tggcctttgc ctctctttcg gagcgtttta gctttcctaa gcgcgtgtcc
    13081 aatattctta agggcgaagg actcttgaat gatgcttctg gtttggtggc ttttcaggta
    13141 gctttgacag cttggacaac tggagctttt tctctggggc aagctagcag ttcgctcatc
    13201 ttttcaatcc taggcggttt tttaattggc tttttaacag ccatgaccaa tcgtttcctc
    13261 catagcttct tgctaagtgt gagagcaacg gatattgcta gtgagctcct tctggaattg
    13321 agtttgccct tggtaacctt cttcctggca gaagaagtcc atgtttcagg gattattgcc
    13381 gtcgtagttg ctggaatttt aaaggcaagt cgcttcaaga aaatcacgct cctcgaagcc
    13441 caagtggata cggtgaccga gacggtctgg catacagtga cctttatgct caacggttct
    13501 gtctttgtga ttttagggat ggagttggaa atgatagcag aacctatctt gaccaatcca
    13561 atctataatc ctctactttt attgctatct ctcatcgccc ttacctttgt cctctttgtc
    13621 attcgtttta ttatgatcta tggctattat gcctatagaa cccgacgcct caagaaaaag
    13681 ctaaataagt atatgaagga catgtttctc ttgacctttt caggtgttaa gggaacggtg
    13741 tcgattgcta cgattctctt gataccaagt aatctagaac aggagtatcc tctcttgctt
    13801 ttccttgttg caggtgtgac gcttgtcagc tttttaacag gtctcttggt cttgcctcat
    13861 ctttctgatg aagaggaaga aagcaaggat tatctcatgc atatcgccat tttgaatgaa
    13921 gtaacgctag agttggaaaa agagttggaa gacactagaa ataaacttcc cctctatgcg
    13981 gctattgaca attatcatgg acgtattgaa aatctcattt taagccaaga aaaccaggat
    14041 gatcaagaag actgggctgc tttgaaactc ttgattctta gtattgaaag tgatggtttg
    14101 gaacaggcct atgaagaggg gaacattagc aatcgtgctt accgagttta ccaacgttat
    14161 ctgaaaaata tagaacaagg aatcaatcgt aaacttgcct caagactgac ctattatttt
    14221 cttgtttcct tgaggatttt acgttttctc cttcatgaag tttttactct cggaaagacc
    14281 ttccgtagct ggaagaacaa ggagcaaagc cgtctccgtg ctcttgatta tgaccaaatt
    14341 gcagagctct atcttgccaa tacagagatg attattgaaa gtttggaaaa cctgaaggga
    14401 gtctacagac gctctttgat tagttttatg caggagtctc gtcttcgaga aacagctatt
    14461 atcagcagtg gtgcctttgt cgaacgggtt atcaatcgtg tcaaacccaa caatatcgat
    14521 gaaatgctga gaggctatta tctggagcgc aagttgattt tcgaatacga agaaaaacga
    14581 ttgattacga ctaagtatgc caagaaatta cgacaaaatg taaataactt agagaactat
    14641 tccttgaagg aagctgccaa taccctaccg tatgatatgg tggaattggt aagaagaaat
    14701 tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtatgtatg
    14761 tgactgactt cgtcagtctt atctacaacc tcaaaacagt gttttgagca gcttgcggct
    14821 agctttctag tttgctcttt gattttcatt gagtataaga ttataagtga aggagtatga
    14881 tatgacatga aaaagtggtg gaaagagctg atagacaaac ctttattaaa agcttttttg
    14941 cattattatc aagcatcaga tagtgagttg accagtgtcg cagtagccta ctattggttg
    15001 atttcgattt tccccctgct tttggtggtg gtcaatatcc tcccctattt tcagattcct
    15061 gtgggagaat ttttgggctt tatgaaagac gttctgcccc caagcctcta tgaaggtgtg
    15121 gaaaaaatag ccagagaagt tttgacgcaa ccttcaacag gtttattgag tttttctgtt
    15181 ttatcggcgt tatggagttt ttcaaaatct atgaatttct tgcaaaaagc ttttaacaag
    15241 gcttatggcg tcgaaaagag tcgtggactt atttcccatc agatgctgag tctcctagtc
    15301 agttttggct tgcagctcct ctttgcgttt gccttgtttt tgatcttatt tggtcagatg
    15361 attttggctt tacttgctca ttattggaca aaagatggca ttatctatca ggctttacaa
    15421 gggttggcag gtcctctgat ttacgccctc ctctttgcta tcttggtcat gctttattat
    15481 tttcttccca atctatctaa caggaaaatt agctataccc taccaggcag tgcctttgtt
    15541 ctcttagtga ttttaggttt actaactctg ttctctagtt atctcaatta ctatgtccat
    15601 catttggtgg atgtccgaat tttaggttcc gttcttcttg ttgttatgat gttttggttt
    15661 atcttgattg ctaaaattgt tatcctaggc gcggttatca atgccagtat gcagagtttg
    15721 aaagatccgg tctttaaaaa agactaacta tttatctatt ataaaagcgc atagtatcaa
    15781 gactttatag aaccttgata ctatgcgctt ttgtgctttg acagtttttt gtatagtttt
    15841 tgtccaagat ttctaaatca tctgattaaa ttcctatttt cccctatcat tgtccctgtt
    15901 ttttcgaaaa tggaaggagt ataataaatc tatcaataaa atgataggag gaactttatg
    15961 ggtcatattt tcttttttct aagtgtcttt ttggcaggga ttctatcctt cttttctcct
    16021 tgtatcttac ctttgttacc ggtctataca ggggtgttac tagatgataa ggatggtgct
    16081 caggcttcta gcggcaaatt ttcaatctca gttactagtt tattacgaac tctggccttt
    16141 atagcaggaa tttcctttat atttattttg ttgggctatg gagctggttt tttaggcgat
    16201 ttgctttatg cttcttggtt ccaatatctt actggggcaa ttattatcct tcttggtttg
    16261 caccaaatgg agattctaca ctttaagggg ctttataagg aaaagaggct acaactgcaa
    16321 ggacaggggc aaaatggtaa gggctatagt caggcatttt tattgggctt gacctttagt
    16381 tttgcttgga cgccttgcgt ggggccggtt ctggggtctg ttttggcctt ggcggcttca
    16441 ggtggttcag gagcttggca gggagctggt ctcatgttgg tgtatacgct gggcttggcg
    16501 ctaccattct tgcttctagc tctgacctct agttatgttt tgaaacattt ccgaaaactt
    16561 catccctatc tcggaatcct caaaaaagtg ggaggttttc tcattattgt gatgggactc
    16621 ttggttctgt ttggaaatgc ttcaatttta agtcaattat ttgaataaaa tggaaaggaa
    16681 tatcaatatg aaaaaatggc aaacatgtgt tcttggagcg ggttcgctcc tttgtttgac
    16741 ggcttgttca ggcaagtccg tgactagtga acaccaaacg aaagatgaaa tgaagacgga
    16801 gcagacagct agtaaaacaa gcgcagctaa agggaaagag gtggctgatt ttgaattgat
    16861 gggagtagat ggcaagacct accgtttatc tgattacaag ggcaagaaag tctatctcaa
    16921 attctgggct tcttggtgtt ccatctgtct ggctagtctt ccagatacgg atgagattgc
    16981 taaagaagct ggtgatgact atgtggtctt gacagtagtg tcaccaggac ataaggggga
    17041 gcaatctgaa gcggacttta agaattggta taagggattg gattataaaa atctcccagt
    17101 cctagttgac ccatcaggca aacttttgga aacttatggt gtccgttctt acccaaccca
    17161 agcctttata gacaaagaag gcaagctggt caaaacacat ccaggattca tggaaaaaga
    17221 tgcaattttg caaactttga aggaattagc ctaggaggtg tcttatgaat gataagttaa
    17281 aaatcttctt gttgctagga gtattttttc tagccataac cggtttctat gttctattga
    17341 tacgaaatgc agggcagaca gatgcctcgc aaattgaaaa ggcggcagtt agccaaggag
    17401 gaaaaacagt gaaaaaaaca gaaattagta aagacgcaga cttgcacgaa atttatctag
    17461 ctggaggttg tttctgggga gtggaggaat atttctcacg cgttcccggg gtgacggatg
    17521 ccgtttcagg ctatgcaaat ggtagaggag aaacaaccaa gtacgaattg attaaccaaa
    17581 caggtcatgc agaaaccgtc catgtcacct atgatgccaa gcaaatttct ctcaaggaaa
    17641 tcctgcttca ctatttccgc attatcaatc caaccagcaa aaataaacaa ggaaatgatg
    17701 tggggaccca gtaccgtact ggtgtttatt acacagatga caaggatttg gaagtgatta
    17761 accaagtctt tgatgaggtg gctaagaaat acgatcaacc tctagcagtt gaaaaggaaa
    17821 acttgaagaa ttttgtggtg gctgaggatt accatcaaga ctatctcaag aaaaatccaa
    17881 atggctactg ccatatcaat gttaatcagg cggcctatcc tgtcattgat gccagcaaat
    17941 atccaaaacc aagtgatgag gaattgaaaa agaccctgtc acctgaggag tatgcagtta
    18001 cccaggaaaa tcaaacagaa cgagctttct caaaccgtta ctgggataaa tttgaatccg
    18061 gtatctatgt ggatatagca actggggaac ctctcttttc atcaaaagac aaatttgagt
    18121 ctggttgtgg ctggcctagt tttacccaac ccatcagtcc agatgttgtc acctacaagg
    18181 aagataagtc ctacaatatg acgcgtatgg aagtgcggag ccgagtagga gattctcacc
    18241 ttgggcatgt ctttacggat ggtccacagg acaagggcgg cttacgttac tgtatcaata
    18301 gcctctctat ccgctttatt cccaaagacc aaatggaaga aaaaggctac gcttatttac
    18361 tagattatgt tgattaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac
    18421 cgtatgtagg gttactgact tcgtcagttt tatctacaac ctcaaagcta tactttgagc
    18481 tgacttcgtc agttttatct acaacctcaa agcggtactt tgagaaacct gtggctatct
    18541 tcctagttta ctttttgatt tttattgagt ataagaggtc tttcctaagc agttagagga
    18601 gaattttgct atactgatac tagtaaatgg taaaggagca gagcatgacc tacacaatct
    18661 taatcgtaga agatgaatat ctggtaagac aaggtttgac taaactggtc aatgtagcag
    18721 cctacgatat ggaaatcatc ggtcaggctg aaaatggaag gcaggcttgg gaattgatcc
    18781 aaaagcaggt tccagatatc attttaaccg atatcaacat gcctcatcta aatggcatcc
    18841 agttggccag tttggtacga gaaacctatc ctcaggttca tttggtcttt ttaacaggtt
    18901 acgatgattt tgattatgcc ttgtctgctg tcaaactagg tgtggacgac tacctgctca
    18961 aacccttttc tcgtcaggat attgaggaaa tgttggggaa aatcaaacaa aaactagaca
    19021 aggaagagaa agaagagcag ttacaagatt tattgactaa taggtttgaa ggaaacatgg
    19081 cccagaaaat ccagtctcat ctggctgata gccaatttag tttaaagtct ttagccagtg
    19141 acttaggttt tagtccgacc tatctgagtt ctttgattaa gaaagagttg ggcttgcctt
    19201 ttcaggatta tctggtgaga gaacgtgtta aacaagccaa gctcttgctt ttaactacag
    19261 atctgaagat ttatgagatc gcagagaagg ttggttttga agatatgaac tattttaccc
    19321 aacgttttaa gcagattgca ggtgtgacac ctcgtcagtt taagaaggga gaagaccgat
    19381 gaagcgttct tctcttttag ttagaatggt tatttccatc tttctggtct ttctcattct
    19441 cctagctctg gttggaactt tctactatca atcaagttct tcagccattg aggccaccat
    19501 tgagggcaac agccaaacga ccatcagcca gactagccac tttattcagt cttatatcaa
    19561 aaaactagaa accacctcgg ctggtttgac ccagcagacg gatgttctgg cctatgctga
    19621 gaatcccagt caagacaagg tcgagggaat ccgagatttg tttttgacca tcttgaagtc
    19681 agataaggac ttgaaaactg ttgtgctggt gaccaaatct ggtcaggtca tttctacaga
    19741 tgacagtgtg cagatgaaaa cttcctctga tatgatggct gaggattggt accaaaaggc
    19801 tattcatcag ggagctatgc ctgttttgac tccagctcgt aaatcagata gtcagtgggt
    19861 catttctgtc actcaagaac ttgttgatgc aaagggagcc aatcttggtg tgcttcgttt
    19921 ggatatttct tatgaaactc tggaagccta tctcaatcaa ctccagttgg ggcagcaggg
    19981 ctttgccttc attatcaatg aaaaccatga atttgtctac catcctcaac acacagttta
    20041 tagttcgtct agcaaaatgg aggctatgaa accctacatc gagacaggtc agggttatac
    20101 tcctggtcac aaatcctacg tcagtcaaga gaagattgca ggaactgatt ggacggtact
    20161 tggcgtgtca tcattggaaa agttagacca ggttcggagt cagctcttgt ggaccttgct
    20221 tggggccagt gtcacatctc ttcttgtctg tctctgctta gtgtggttca gtcttaaacg
    20281 ctggattgct cctttgaagg atttgagaga aaccatgttg gaaattgctt ctggtgctca
    20341 aaatcttcgt gccaaggaag ttggtgccta tgaactgaga gaagtaactc gccaatttaa
    20401 tgccatgttg gatcagattg atcagttgat ggtagctatt cgtagccagg aagaaacgac
    20461 ccgtcagtac caacttcaag ccctttcgag ccagattaat ccacatttcc tctataacac
    20521 tttggacacc atcatctgga tggctgaatt tcatgatagt cagcgagtgg tgcaggtgac
    20581 caagtccttg gcaacctatt tccgcttggc gctcaatcaa ggcaaggact tgatttgtct
    20641 ctctgacgaa atcaatcatg tccgccagta tctctttatc cagaaacaac gctatggaga
    20701 taagctggaa tacgaaatta atgaaaatgt tgcctttgat aatttagtct tacccaagct
    20761 ggtcctacaa ccccttgtag aaaatgctct ttaccatggc attaaggaaa aggaaggtca
    20821 gggccatatt aaactttctg tccagaaaca ggattcggga ttggtcatcc gtattgagga
    20881 tgatggcgtt ggcttccaag atgctggtga tagtagtcaa agtcaactca aacgtggggg
    20941 agttggtctt caaaatgtcg atcaacggct caaacttcat tttggagcca attaccagat
    21001 gaagattgat tctagacccc aaaaaggaac gaaagttgaa atatatataa atagaataga
    21061 aactagctaa ctcccagtca attctgggag ttttatgcgt aattgggcaa actttctagg
    21121 ttgtctatct tgctaaaaac aagaaaaaac ggtatgatag aagagtgaca acagaggtaa
    21181 cagagatgaa cgagacacag attcaaagag aaacacgtca ggtagtggaa gatgttttag
    21241 aaaagaccaa tttgaaacag ggggcccttt ttgttttagg tctatcttct agtgaggtgc
    21301 taggtggtca gattgggaaa gaatccagtc aagagattgg tgagctgata gtggagacta
    21361 tcttgggtat tctaggtagt agaggtatcc atttagcagt tcaaggttgt gagcatgtca
    21421 atcgggctct cgttgttgaa cgtcaggtgg cagagcagtt tggtctggaa attgtcagtg
    21481 tccatcctac tcttcatgca ggaggttcgg ggcagttggc agcctttaag tttatgcagg
    21541 atccagttga ggttgaattt atcaaggctc atgctggatt ggatatcgga gacactgcaa
    21601 ttggcatgca tgtcaagcat gttcaggttc cgattcgccc tattttgaga gagattggtc
    21661 atgcccatgt aacggcactg actagtcgtc caaaattaat cggaggtgcg cgtgcgcact
    21721 atccgcaaga tgctattagg aagttttgag aatgaataaa ggagataaaa gtgtttaaaa
    21781 aagaccgttt ttcaattcgt aagattaagg gagttgtagg ctctgtattt cttggaagcc
    21841 ttttgatggc tccttctgta gtggacgcag ccacctatca ctatgtaaat aaagagatta
    21901 tttcacaaga agctaaagat ttaattcaga caggaaagcc tgacaggaat gaagttgtat
    21961 atggtttggt gtatcaaaaa gatcagttgc ctcaaacagg gacagaagca tctgttttga
    22021 cagcttttgg tttgctgact gttgggagct tgcttttaat ctacaagaga aagaaaattg
    22081 ctagcgtctt tctagttgga actatgggat tggtagttct tcctagtgca ggggctgtag
    22141 acccagttgc gaccctagca ctggctagtc gagagggtgt tgttgaaatg gagggctatc
    22201 gctatgttgg ttatctatca ggtgacatcc tcaaaacgct tggcttggac actgttttag
    22261 aagaaacctc agcaaaacct ggagaggtga ctgtagtcga agttgagact cctcaatcaa
    22321 caacaaatca ggagcaagct aggacagaaa accaagtagt agagacagag gaagctccaa
    22381 aagaagaagc acctaaaaca gaagaaagtc caaaggaaga accaaaatcg gaggtaaaac
    22441 ctactgacga cacccttcct aaagtagaag aggggaaaga agattcagca gaaccagctc
    22501 cagttgaaga agtaggtgga gaagttgagt caaaaccaga ggaaaaagta gcagttaagc
    22561 cagaaagtca accatcagac aaaccagctg aggaatcaaa agttgaacaa gcaggtgaac
    22621 cagtcgcgcc aagaaaagac gaacaggcac cagtcgagcc agaaaatcaa ccagaagctc
    22681 ctgaagaaga gaaggctgta gaggaaacac cgaaacaaga agagtcaact ccagatacca
    22741 aggctgaaga aactgtagaa ccaaaagagg agactaaaac agctaagggg acgcaagaag
    22801 aagattacgt gggtgaggct cttgttccag aacaattacc tgagtataag gtgactgaag
    22861 gaacactcgt tgaagaatca actacagaac ttgactataa aactgaaacg actgaggacc
    22921 caaccaagta cacggacgaa gaaactgtcc tacgaaatgg tgaaaaagga agtcaagtta
    22981 caaaaacaac ctataaaaca ataggagggg ttaaaactga ccaagttctt tcaaccagta
    23041 cggaagtcac caaggagcct gtaaatcaac aggtaatccg tggtacaaaa ccaattgaag
    23101 ggacaacggt tgagacaaga gaagaaatca ttccttttga aacaaaagaa caagaagatg
    23161 acactttaaa acgcggaaca agacaagtaa ctcaagaagg tgtaaacgat aagaaacaaa
    23221 ttactgaaac ctataaaaca attcgcggag aaaaaacaag tgacgctcct actatcacag
    23281 aaacagtgat tgaaaaacct caagacaaaa ttattaagaa tggcacaaaa gagttagaga
    23341 aaccaacctt ggaatgggct aaaacagata aagatgtctt gaagaagagt gcgacagcta
    23401 gttatacatt gactaaacca gctggagtag aaattaaatc gattaaagta gctctaaaag
    23461 ataatactgg aacagttgtt aaagaagtaa cggtagaaga aaataactta caagctactt
    23521 tagacaactt gaaatattat caaggttata cactatccac aaccatggtc tatgatcgag
    23581 gtaacggtga agaaactgaa atattagaag ataaagaagt tcagttagac cttaaaaaag
    23641 ttgagattaa agatattaaa gaaacaagat tgatgaaagt ggatgagaat ggaaatgaaa
    23701 cagatagtag ccttctagaa actgttccag aaaatctaac gtcatattat ctaaaaatta
    23761 ccactaatca taataaagta acaaggcttg ccattactaa tatagaggaa gtaactgagg
    23821 aggagacatc cttatttaaa gttactgctt cagctcctga tttaatccaa cgtgattcaa
    23881 ataatagttt gagtcaaaca tacacttatt acatagagaa acccaaagca tcgcaaaata
    23941 acgtttacta taacttcaaa gatttagtag atgctatgca gaaaaatcct aacggtgagt
    24001 ttaaattagg atcggattta aatgcaacaa atgtacctac accaagtaaa tcatatgtaa
    24061 caggtaaatt tacaggtcac ttaacaagtg ttgatggtaa gcatttctcc attcataaca
    24121 ctgctcgtcc attatttgat agagttgaag ggggttctat caaaaatatt aatttaatta
    24181 acgttaatat taatatgcct tgggcaaatc aattagcttc attagctcaa acagtgaaaa
    24241 atgcaactgt tgaaaatatt aaagtaacgg gtactatcgt tggtaataac aatgttgcgg
    24301 gtattttgga taaattagat gatgcaggta ttatgactaa tgttgctttt atcggaaaag
    24361 ttcaatctgt tggtgataaa gggtggaact tggctgggat tgcatctgag atttatcgag
    24421 gcaatttaaa taaagcttat gcagatgttg aacttaaagg tttaaatact cgtgcaggtg
    24481 ctatagtagg acatttagct catgatttta atccaagaga tgttggtgct tggtctaatg
    24541 taagaaattc tgtagccaaa ggtactattg atgttgctag aggtgatgta ggcggtttaa
    24601 ttggtaaaga ctggccttgg ggaaccattg ataacaatat cagcttagtg aatgttaagc
    24661 gtggtgatat tttctttggt tctaatgata tggatgatga atttgtaagc aattggatta
    24721 aacctaataa tgcaacagtt atcggtgtga gttctggaga taaaacccat aaacaatcgt
    24781 ctaaaattaa agaaatttca caggtagaag ctgataagaa aattaaggat atgggtatca
    24841 ctgctgatac atttgaagta actgagcatt tggttgataa gttgaatcgc cgtatattac
    24901 gtgatgaaga atacaaaaca attcaagatt ataatgcaaa tcgtgagctt gtttatcgta
    24961 atgttgaaaa actccaaccg ttctacaaca aagaatggat tgtgaatcaa gggaacaaac
    25021 ttacaactga tagtccatta atgaataaag aagtattgtc tgtgactgca atgaaaggta
    25081 atgactttat tacagacctt acagatgctg accatattat ggttcattac gcagataaga
    25141 caaaagatat ctttacgatt tctcctaaag actctcaagt taagcaagta aaagaataca
    25201 gtgtcgcaga gcttggtgaa gtcgtctata caccaaatat ggttgttaaa gatcgtgcag
    25261 atttaattag tgctattgaa ggtattttaa gtccaattga attacaatct gatccaattt
    25321 atcaacgatt aggaagaact ggggataaca gagttaatgc aattaagaat ctttacttag
    25381 aagaaagctt taaagaagta aaagatcatc ttaatacatt tgtgacaaaa ttagttgaaa
    25441 atgaagatca tcaactgaat acagatgaag ctgcaaaacg tgccttgatt aagaaaattg
    25501 aagataacaa agctgctgtc ctgttaggat taacatacct aaatcgttat tacggtgtga
    25561 aatttgataa cttcaatatt aaagaattaa tgctattcaa accagatttt tatggtaaga
    25621 atgtaagtgt tttagatcga ttaatagaaa ttggttcaaa agaggactat attaagggaa
    25681 gtcgtacaca ggagtccttc cgtgaagtgg tggcgaaaaa tactctttct ggaaacttac
    25741 atgacttctt gacctacaat atgaaactat tcacaaatga aacagacata aatgtttggt
    25801 ttaagaaagc tattgaaaat aatgcttatg tagttgaaca accgtcaact aaccctgcat
    25861 ttgctaataa aaaatatcgt ctatatgaag gacttaataa cggacaacat ggacgcatga
    25921 ttttatcgct tctgaacttg aaagatgcac atttatttat gatttcaaca tataatacta
    25981 tctcatttag ttcgtttgaa aagtatggta aagatacaga agaaaaacgt gaaacgttca
    26041 agagtgaaat caataaacgt gctaaagagc aagttaatta cttagatttt tggtcacgcc
    26101 ttgccactga taatgtccgc gataaacttc ttaagagtca aaatgtagtt ccaactcctg
    26161 tatgggataa tcatggtgca cccggtggtt ggcctgatag atttggtcat cgaaaagata
    26221 aaccggatta tgcacctatt cgtgaattct ttggacgtat tgataagtat catgattata
    26281 agtatgggta tggagcgtat gcttacatct ttgctgatcc acagcctatg gatgctgtat
    26341 attttgttat gtcggattta ataagtgaat atggcacatc tgcctttaca catgagacta
    26401 cccacgtaaa tgaccgaatg gcatatctgg gaggtcatag acatcgacag ggtacagatc
    26461 ttgaagcatt tgctcaaggt atgttacaaa ctccagcaga acatggacat caaggtgaat
    26521 atggcgcact tggattaaat atggcatttg aacgttcaaa tgatggaaac caatggtata
    26581 atccagatcc taccaaactt caaacacgtg accaaatcga ccattacatg aagaactaca
    26641 atgaagctat gatgatgctc gattatgcag aagctgaggc tgttcttcct aaggttaaag
    26701 gtgacaatag taagtggttc aagaaaattg atcgcgaaac acgtcgacca atggacagaa
    26761 ataaactaag tggtcctcac caatgggaca aagtgcgtga tttgatagac gctgagaaaa
    26821 caactaacct tgaaaccatc gatgacttgg taaataataa tttcatgacc attcacggaa
    26881 atccaggtaa taaggtcttc cacccagagg actttggtac ggcatatgtc aatgttaata
    26941 tgatggctgg tatttatggc ggtaatacga gtcaaggtgc ccctggttct ctatccttca
    27001 aacataacgc cttccgtatg tggggttact atggatatga acatgggttc attgactatg
    27061 tttcaagcaa acatcaaggt gcagccaata aagaaaataa cggtctatta ggtgatgatt
    27121 tcattattaa gaaagtttct aataaccaat tttcaaacct tgaagattgg aagaagcaat
    27181 ggtatgggga agttcttaca aaatctaaaa aaggttttgc accaattgaa attaatggca
    27241 ctcaaatttc aacctatgaa cagttgaaga ctatgtttga tgaggctgtt actaaagatt
    27301 taacggaact aaacgatagt agtattaaag acaaataccg aaatacagtt gtcttgaaat
    27361 cgaaagtctt taaagctctc cttaaaaaca cagacggttt ctctggtgat ctatttactg
    27421 caccacaagc atagaatgaa taaaatcgta aaaaggtaga tcagctttgt ctgtatctgc
    27481 ctttttatgc tatacttaag gtatgcatag aaaaacagtg attgatttta ggactttggg
    27541 ggagagatat acctttacca agcctattaa agagttgaaa acgagaaatg tagaagaagt
    27601 ggcagatttg ctggcacaag tggaaagcta ccaagagcaa ggttattatg tggtggggta
    27661 tgtcagctac gaggctgcac ctgcttttga ggaaaaatta gcagttcaca aggatcccct
    27721 actgggagag tacctgcttt attttactgt tcatgatagc gtagaaactt cccctattcc
    27781 tctgacttat gaggatattg atttgccctc aaattggcag gaagtaacgt ctgcagcaga
    27841 ctatgaaaag gccattgccc aaattcacca tcatttacgg cagggagata cctatcaggt
    27901 caactacacc gtccaactta agcaaaagtt aaatgccaat ccttttgcca tctacaatcg
    27961 tatggtggta gagcaggagg cgggctacaa tgcctatgtg gaacatgacg agatggcagt
    28021 gatttccatg agcccagagc tcttttttga gcaaaatgat cgcgagttga caacacgacc
    28081 aatgaagggg acgactcagc gtggggtaac tgaccaagaa gatcttgaac aggccagttg
    28141 gttggaacag gatcccaaaa atcgctctga aaatatgatg attgtggacc tcttgcgcaa
    28201 tgatatgaac cgtatttctg aagttgggag cgagcacgtg gagcgtctgt gtcaggtaga
    28261 gcagtattca actgtttggc agatgacttc gaccatcaag agtcagttgc gagaggatgt
    28321 ggaccttgtt gaaatcttcc gctcactctt tccttgtggt tccataacgg gtgcaccgaa
    28381 aattgcgaca atggagatta tcaaggactt ggagcctcaa ccgcgtggag tctactgtgg
    28441 aacgattggt ctcttgcttc caaatggacg acggattttt aatgtggcca ttcgtaccat
    28501 tcaacttcac aaaggtcaag ccatttatgg agttggcgga gggattactt gggatagcac
    28561 atgggaatct gaataccgag aggttcatca aaaggcagca gttctttatc gtaaacaagc
    28621 tcgcttccaa ctgattacga caggggaaat cagccagaag aacctgttgt ttgaagatca
    28681 acatctggaa agactgagaa aagctagtcg ttattttgcc tttccttttg atgcagaaga
    28741 cttgggacac aagattgagg aagagtgtca ggattgtgaa gctaatcgag attaccgctt
    28801 gcgaatcagc cttagcaaat ctggagagat agaagtcaat cgtcaagtat taacccctct
    28861 cagtacaagc ttttgtcagg cccaagtctg ccttcaggaa gctgctttga atcaatcctt
    28921 tacctacttt aaaaccactc accgaccgca tttgagccta ggagaacaag agaagattta
    28981 ccacaataag tcaggagaac tgcttgaaac ctctatagga aatttggttc tgaaaatcgc
    29041 tggaaaactc tacacaccgc ctatccgact tggaatcttg ccaggaattt accgtcagta
    29101 tttgctagaa acaggacagg tagaagagaa agtcttgacc ttggcagatt tagcccaagc
    29161 agaagctatt tacggctgta atgcagtgag aggcttgtat gaactaagcc ttgaggagaa
    29221 ctagatgaaa ctgatatttt tgcatgggtt agggcagtca gcagagtctt ggaaagaagt
    29281 tcggaatcta ctgacagatt atccttctga ggctatcgag ttatttcctt ctggagttag
    29341 taactatcaa caagctaagg agcgagttta tcagcaccta gctcaagaga cagaaccttt
    29401 tgttttgatt ggattgtcct taggtgctgc cctggcacta gaactttcca gttacgattt
    29461 accaaatctt cgagctttga ttctgtcaag atgcccgctt aaattagcag ggaatatcct
    29521 attttatctt cagttgctga tttttaaact acttcccaaa agagtatttg aaaaacaggg
    29581 agcagacaag gctcttatgg tcggagtttc tgaggagttg aagacacttg atttaacgga
    29641 tatagcagga acttgccctt atccaacctt actaatttgt ggtatcaaag ataaaccgaa
    29701 tcttagttct atgagaagtc ttcataaact aatatcagaa tcccaatttc agattatccc
    29761 agatggccct catgtcttga ataaggcaaa accaaaggag tttgtagaaa agaccagaag
    29821 tttccttgaa ttgctgaaat aagtttgata aaataatatt gaaatcgata tcataattat
    29881 gggagaaaga aatgaataaa cgtctatttt taaaaatgag tctggtgacg ttgccaattt
    29941 tagccttgtt ttcacaacca gttttggcgg aagaaaacat ccatttttcg agctgtaagg
    30001 aagcttgggc gaatggctat tcggatattc acgagggaga acctggttat tctgccaagt
    30061 tagaccgtga tcatgatggt gtggcttgcg aattgaaaaa tgctcctaag ggtgctttta
    30121 aagcaaaaca gtcaacggct attcaaatca acacaagttc agcaacaaca agtggttggg
    30181 ttaagcagga cggcgcttgg tactactttg atggaaatgg aaatctagtg aaaaatgcat
    30241 ggcagggaag ctattacctg aaagctgatg gtaaaatggc ccagagtgaa tggatttatg
    30301 actcttctta tcaagcttgg tattatttga aatcagatgg ttcttatgca aaaaatgcat
    30361 ggcaaggagc ttattacctt aaatcaaacg gtaaaatggc acaaggtgag tgggtttatg
    30421 attcttctta ccaagcatgg tattacttga aatcagatgg ttcatatgct cgcaatgcat
    30481 ggcaaggaaa ctactatttg aaatcagatg gtaaaatggc taaaggtgaa tgggtttatg
    30541 atgccaccta tcaagcttgg tattatttga catcagatgg ttcttatgct tacagtacat
    30601 ggcaaggaaa ttactatcta aaatcggatg gtaaaatggc tgtcaatgaa tgggttgatg
    30661 gtggacgtta ttatgttggc gctgacggag tttggaagga aggtcaagca agtacagttt
    30721 cttctagtaa tgatagcaat agtgaatatt ctgctgcttt aggaaaggca aaaagttata
    30781 attcgttatt ccacatgtca aaaaaacgta tgtatagaca attaacttct gattttgata
    30841 aattttcaaa tgatgcagct caatatgcca ttgatcattt agatgattaa cagatactgg
    30901 taggcgaaaa aattccttat aattcattta cgcaaacctt tgcataagtg aatggatttt
    30961 gatatactag tactgtaagc attttcaatt actacacaat gaaaaaggag aatatgatga
    31021 gtcaaaagat tattgggatt gaccttggtg gaacttctat caaatttgca atcttaacaa
    31081 cagcaggaga aatccaagga aaatggtcaa tcaagaccaa cattttggat gagggaagtc
    31141 atatcgttga tgatatgatt gagtctattc aacatcgttt ggacttgctt ggattggcag
    31201 cagcggactt ccaaggcatt ggaatgggat caccaggtgt ggttgaccgt gacaaaggga
    31261 ctgttatcgg tgcctacaac ttgaactgga aaacccttca accaatcaaa caaaagattg
    31321 aaaaagcttt gggcattcca tttttcatcg ataatgatgc caacgtagca gctcttggtg
    31381 agcgctggat gggtgctgga gataaccaac cagacgttgt ctttatgaca ctcggtactg
    31441 gtgttggtgg cggtatcgtc gcagaaggca aattgcttca cggtgttgct ggtgcagcag
    31501 gtgagcttgg tcacatcact gttgactttg accagccaat ctcatgtact tgtggtaaaa
    31561 aaggctgcct tgagacagtt gcttcagcaa cagggattgt caacttgact cgtcgctatg
    31621 ccgatgaata cgaaggcgat gcagccttga aacgcttgat tgataacgga gaagaagtaa
    31681 ctgctaagac tgtctttgat ctcgcaaaag aaggagacga ccttgctttg attgtttacc
    31741 gtaacttctc acgttacttg ggaatcgctt gtgctaacat tggttcaatc ctaaacccat
    31801 caacaatcgt catcggtggt ggtgtgtcag ctgcgggaga attccttcta caaggtgttc
    31861 aaaaagttta cgatgaaaat agtttcccac aagtacgcac atctactaaa ttagctcttg
    31921 caactctagg aaatgacgct ggagttatcg gagcagcatc acttgtattg caataagata
    31981 atgagagagg aaaatgctaa cctagagtta gtaatgttcc tcttttattt tttatgctat
    32041 actagttagg acaatgaatg aggtgagagt aaatgacaaa agcagatacg atttttaaag
    32101 agaatattga acgcattcta aaggaaggtg ttttctcaga gcaggctcgt cctaagtaca
    32161 aggatgggac tgttgctaat tccaagtatg taactggtgc cttttccgag tacgacttat
    32221 ctaaaggaga atttcctatc acaaccttgc gtcccattgc aatcaaatcc gccatcaaag
    32281 aagttctctg gatttaccaa gaccagtcaa atagcttaga agtgcttaat gacaagtaca
    32341 atgttcacta ctggaatgac tgggaagttg gagacacggg aaccattggt gagcgctatg
    32401 gtgccgttgt taagaaacac gacattatca ataagcttct caaacagttg gaaaccaatc
    32461 cttggaaccg ccgcaatatt atttcgctct gggattacca agctttcgaa gaaacagatg
    32521 ggctgctccc gtgcgccttt cagaccatgt ttgatgtccg gcgtgttgat ggggaaatct
    32581 atctggatgc gaccttgacc cagcgctcca atgatatgct ggtggcccac cacatcaacg
    32641 ctatgcagta tgtggctttg cagatgatga ttgccaaaca ttttggctgg aaggttggga
    32701 agttcttcta cttcatcaac aacctccata tctatgataa tcaatttgaa caagctcagg
    32761 aattgctccg tcgggagccg tcaaactgcc aaccacgctt ggttttaaat gttcctgatg
    32821 ggactaattt ctttgatatc aaagcagaag attttgagtt ggtggattat gaccctgtta
    32881 agccacagtt gaagtttgac ctagctattt aaaagaatag aaaaaagaag ttgagaataa
    32941 tcccaacttc ttttgtttct taacgtgata cgcggcgacg agctgctttt ttacggtttt
    33001 cttcgatgaa agctgctttt tgctcttctg gttcgattac tttcttttta aatgcgtata
    33061 ctgcacctgc aacggcagcg acagttcctg cgacacctgt tacaagacct ttagcgaatc
    33121 ctttagccat gagtcttcct cctttatatt ctcaatcagc cagcctcctc aagaggtcac
    33181 atttttctga ctgacctttt tgtgttataa taatagtaac gaaaaaatgg gaatttttca
    33241 aggaaaaaag atgaaaacaa aaataattgt gattgttgga ccgactgctg ttggaaagac
    33301 ggctctagct attgaagttg caaagcgttt taatggcgaa gtggttagtg gagatagcca
    33361 gcaagtctat cgaggacttg atattgggac ggccaaggct agtccagaag agcaggcagc
    33421 tgttcctcat catttaatcg atgttagaga gataaccgag tcttactcgg cttttgattt
    33481 tgtttcagaa gctaagatga ctattgaggg tattcacaac cgtggcaagc tagccattat
    33541 cgccggtggg actggacttt atatccagag cttgctagaa ggttaccacc taggtgggga
    33601 gactcctcat gaggagattt tagcttatcg agctagtttg gagccatatt cagatgagga
    33661 attagcccat ttggtggatc aagcaggcct tgagattccc cagtttaatc gtcgtcgtgc
    33721 tatgcgtgcc ttagaaattg cccattttgg tcaggatttg gaaaatcaag agaccttgta
    33781 tgaaccgctg attatctgct tggatgatga acgtagtcaa ctttatgagc gtatcaacca
    33841 ccgagtggat ttgatgtttg aggctgggct tttggatgag gccaagtggc tgtttgacca
    33901 ttcccctaat gtacaggctg ctaaaggaat tggctataag gaactctttc cttatttccg
    33961 tggagagcag accttggagg aagctcgtga gagtctcaaa caggctactc gtcgttttgc
    34021 caagcgtcag ctgacctggt tccgtaatcg catgcaggtc accttttatc agattggaga
    34081 atctggtgta caagaccgca ttttaagcca gatagaggag tttttagatg attgaaacgg
    34141 agaaaaaaga ggagcgggtc ctgctgattg gtgtggaatt gcagggtatg gacagttttg
    34201 acctctccat ggaagaattg gctagtttag cgaaaacggc aggggcagtc gttgtagata
    34261 gctacagaca aaaacgtgaa aaatatgatt ccaagacctt cgtcggctct ggtaagttgg
    34321 aagagattgc gcttatggtg gatgcagaag aaatcactac tgtcatcgtc aacaaccgtc
    34381 tgaccccaag gcagaatgtc aatctagagg aagttctcgg tgttaaggtc attgaccgta
    34441 tgcagttgat tttggatatc tttgccatgc gggctcgaag ccatgaaggg aagctccaag
    34501 tccacctagc ccaactcaaa tacctcttgc ctcgcttggt tggtcagggg attatgctca
    34561 gccgtcaggc agggggaatt ggttcccgtg gtcctggtga aagccaactg gagctgaacc
    34621 gtcgtagcgt tcgcaatcaa atcacggata tcgagcgcca gcttaaggtg gttgagaaaa
    34681 atcgtgcgac tgtcagagaa aaacgtttgg agtctagcac ctttaagatt ggtttgattg
    34741 gttataccaa tgctgggaaa tcaactatca tgaacatctt gaccagtaag acccagtatg
    34801 aagcagatga gctctttgcg actctggatg cgacaaccaa gagtattcat ctaggaggca
    34861 atctccaagt aactttgaca gataccgttg gctttatcca agatttgccg acagagttgg
    34921 tgtccagttt caagtcaacc ttggaagaaa gcaagcatgt ggaccttctg gttcatgtta
    34981 tcgatgctag caatccttac cacgaggagc atgaaaaaac ggttctctcc atcatgaaag
    35041 acctggacat ggaagatatt cctcacttga cgctttataa taaagcggat ttggtggagg
    35101 atttcacgcc tacccaaacg ccatataccc tcatttctgc caagtctgag gacagtcgtg
    35161 aaaacttgca agcattattg ctagataaga ttaaggaaat ttttgaagca tttaccctgc
    35221 gagtgccttt ttcaaagtcc tacaagattc atgatttaga gagtgttgcg attcttgaag
    35281 aacgtgatta tcaggaagac agcgaagtga ttacaggcta catttccgag aaaaataaat
    35341 ggaggttaga agaattttat gactgatatt aaaactttgg ctctaaagta tggaggttat
    35401 acaagtctgg acaaggtcta tctggatcag cttctagctg gtaaaacaga gcaggagcag
    35461 ttaacactta ttacacctcc gccaagtgtt gttaatgcct actttgcaga actctatcag
    35521 aaaaagagtc ctcaggctgc gacggattat tttgcagaac tcagtcagga actgaatctt
    35581 tacaatactg agccaagttt caccctagaa aataagtctt ttattcggct taatctgtct
    35641 ggtaaatcct ttggtttttg ttatgagagt gacggctttg gtcggatttt ctctgaaaat
    35701 gaggagaaaa tctcggatga cttgctcttt gaaattgcgc aaattttccc ccatcaatta
    35761 gtctttgaag agtctggtaa gatttacatg aagcctgtcg aggacgagga agttgtcagc
    35821 ctagaaagtc tcacagcttt gactgatttg gaaagattgg ctgatggtcg aaaacgtctc
    35881 aaaggctaca gccaagagga tttattgaaa gaagctgctg ctttttctgg caaacgctat
    35941 ttccgatcgg aaaaccgcac agccatgtta tatattgatt aattagaaag tatcgaatgg
    36001 atattcaatt tttaggaacg ggggctggtc agccctctaa agcccgcaac gtttcaagtc
    36061 tcgccctgaa acttttggat gagattaacg aagtttggct ctttgactgt ggagaaggta
    36121 cgcaaaatcg cattctggaa accacaattc gaccacgtaa ggtcagcaaa atctttatta
    36181 cccatctgca tggagaccac atttttggtt tgccaggttt cctttctagc cgtgcctttc
    36241 aggccaatga agagcagaca gatttggaaa tctacggacc tcaaggaatc aagtcatttg
    36301 tcttaaccag ccttcgtgtg tcaggttctc gtctgcccta ccgcattcat ttccatgagt
    36361 ttgaccaaga ttctctgggt aaaattcttg aaaccgataa attcactgtg tatgcagagg
    36421 agctggacca cactattttc tgtgttggct atcgtgtcat gcaaaaggat ctagaaggga
    36481 cgctggatgc taaaaaactc aaggctgctg gtgttccgtt cggcccgctt tttggtaaaa
    36541 tcaaaaacgg ccaggatctt gttttggaag acggaactga aatcaaggca gcagactata
    36601 tctcagcgcc acgtccaggt aagattatca ctattttagg agacactcga aaaacggatg
    36661 ccagtgtgcg tctggctgtc aatgcagatg tcctagttca tgagtccact tatggcaagg
    36721 atgatgaaaa aattgctcgt aaccatggtc actcaactaa tatgcaagct gcacaagtag
    36781 cggtagaagc aggtgccaaa cgcctcctac tcaaccatat cagtgcccgt ttcctctcaa
    36841 aagatataag caaactcaag aaagacgctg ccacaatttt tgaaaatgtc catgtggtca
    36901 aagacttgga agaagtggaa atctagcagt cacagaaagg ataagtatgc ctactattct
    36961 cattaccgga gctagcggtg gtctagctca agaaatggtc aaactcctgc ccaatgacca
    37021 actcatcttg cttggtagaa ataaggaaaa attagcccaa ctctacggaa attattccca
    37081 tgcagaattg attgaaattg atattaccga cgattcagcc ctagaagctc tggtaactga
    37141 tctttatctc cgctatggca agattgatgt cttgattaac aacgctggtt acgggatttt
    37201 tgagggattt gaccaaattg ctgataaaga cattcaccag atgtttgagg tcaatacctt
    37261 tgccctgatg aatctgtctc gtcaccttgc ggctcgtatg aaggaaagca gcaaagggca
    37321 tatcatcaac atcgtcagca tggcaggtct aatagctact ggcaagtcta gtctttactc
    37381 agcgaccaag tttgcggcta ttggtttttc aaatgctctg cgactcgaac ttatgcccta
    37441 tggagtctat gtgacaacag tcaatccagg tccaatccga acaggatttt ttgaccaagc
    37501 tgacccagat ggaacttatc ttaaatcggt tgaccgcttc ctcttagagg cagatgcagt
    37561 ggctaaaaag attgtcaaga ttataggcaa aaataaacga gaactcaatc tcccgatttt
    37621 gttgaaccta gcccataagt tttatactct ctttcccaag ctagctgata agttggcagg
    37681 ggaaactttt aattataagt aaaaagaacc aatgtgcagg ttgttgctag cctacatatt
    37741 ggttcttatc atttctcaac tatcaaactg aacttcttct agtagatagt cgataaagcg
    37801 ttcgcccatc ttagataggc tggttttctc atgctggata tagaccagct caatcgggtc
    37861 atcaatatcc agtgggatag aaacgatatt gtctccgttt aggttgctgt tcaaaatccc
    37921 tgtcgcaatg gtataaccat ccaaaccaat caagagatta aagagggtgg cacggtcact
    37981 gaccacaatg gatttcttgt ggtgttcttg agaaagaatc tcttctgaaa agtagaagga
    38041 gttgtgcgtc ccttggtcat agctgaggta agggaaattc tccaaatcag acagtttcac
    38101 cttgtctttc tttgccagag ggttggtctt gctgacaaag atatgcggtt gcgctgtgaa
    38161 gagatggtgg gctagcaggt gattgtcatc cagcatcttg gttaaaacat cacggttgta
    38221 actgtttaag aagaggaccc cgacctcact gcggaagttc ttgacgtcgt cgataatctc
    38281 ccaagtccga gtttcacgaa ggaagagttc gtatttctcc atatcgcttt tcttgagcaa
    38341 agagacaaag gcattgacca caaaggcata gtgttgagac gaaacgctaa agagttcgcg
    38401 gtgggcgaca ggatttttat agcgttcctc cagaagctgg gtctgctcga caacctgacg
    38461 ggcataagag agaaactcca tcccatcacg ggtcaaggtg attcccttgg gattgcggat
    38521 aaagatctca atgcccattt cattttccaa atctcgcact gcattggaga gacttggctg
    38581 agtgataaag agttgcttgg ctgcctcatt catggagcca gtttcgacga ttttgataat
    38641 ataatgtaat tgttgaattc tcatgttttt attgtaccat acttgcctta gaatcgctaa
    38701 agaagatagg aaaataagga gcattgtgtg agtctcttct tgaaaaaaac acaaaatttt
    38761 gctagaatga gtcttatgaa aacattctat gatgtgcagc aattcctcaa acgatttggt
    38821 attattgttt acatgggaaa acgcttatat gatattgaac tgatgaagtt ggaactatct
    38881 cggatttacg atgcagggtt gatggataaa ttagactatc tagaggcaga agcagttctt
    38941 cgcagagagc acaaggtaga attggattat attgagaaaa atggagaaaa gaactaatgg
    39001 ttacttggat tttgtgggca cttatactag caatgttggc gtggatgggc tttaactatc
    39061 ttcgtattcg ccgtgcggct aaaattgtgg acaatgagga gtttgaagcc ttgattcgta
    39121 cgggtcaatt gattgatttg cgcgacccag cagaattcca cagaaaacat atccttggtg
    39181 cacgcaatat tccttcaagt cagttgaaaa ctagtcttgc agcccttcgt aaagataaac
    39241 ctgtccttct ctacgaaaac caacgtgcgc aacgagttac aaatgcagct ctttacttga
    39301 aaaaacaagg tttttctgag atttatatcc tttcttatgg cttggattct tggaaaggga
    39361 aagtgaagac tagctaacct tatttccaaa ttagtcgaat gataggatga agatattgtt
    39421 ttatagtata at
//
LOCUS       DBERDS010000017        37038 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.017, whole genome shotgun sequence.
ACCESSION   DBERDS010000017 DBERDS010000000
VERSION     DBERDS010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 37038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.017"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..467
                     /locus_tag="ACL73E_000978"
                     /pseudo
     CDS             1..467
                     /locus_tag="ACL73E_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            551..1258
                     /locus_tag="ACL73E_000979"
     CDS             551..1258
                     /locus_tag="ACL73E_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0800968.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1259..2590
                     /gene="pnpS"
                     /locus_tag="ACL73E_000980"
     CDS             1259..2590
                     /gene="pnpS"
                     /locus_tag="ACL73E_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGS0800969.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2757..3632
                     /locus_tag="ACL73E_000981"
     CDS             2757..3632
                     /locus_tag="ACL73E_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGS0800970.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3750..4613
                     /gene="pstC"
                     /locus_tag="ACL73E_000982"
     CDS             3750..4613
                     /gene="pstC"
                     /locus_tag="ACL73E_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGS0800971.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4606..5421
                     /gene="pstA"
                     /locus_tag="ACL73E_000983"
     CDS             4606..5421
                     /gene="pstA"
                     /locus_tag="ACL73E_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGS0800972.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5423..6175
                     /gene="pstB"
                     /locus_tag="ACL73E_000984"
     CDS             5423..6175
                     /gene="pstB"
                     /locus_tag="ACL73E_000984"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGS0800973.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6190..6840
                     /gene="phoU"
                     /locus_tag="ACL73E_000985"
     CDS             6190..6840
                     /gene="phoU"
                     /locus_tag="ACL73E_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGS0800974.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            6902..7333
                     /locus_tag="ACL73E_000986"
                     /pseudo
     CDS             6902..7333
                     /locus_tag="ACL73E_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7448..7582)
                     /locus_tag="ACL73E_000987"
     CDS             complement(7448..7582)
                     /locus_tag="ACL73E_000987"
                     /inference="COORDINATES: protein motif:HMM:NF037495.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800975.1"
                     /translation="MFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW
                     "
     gene            complement(7747..7887)
                     /locus_tag="ACL73E_000988"
                     /pseudo
     CDS             complement(7747..7887)
                     /locus_tag="ACL73E_000988"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            8099..9115
                     /locus_tag="ACL73E_000989"
     CDS             8099..9115
                     /locus_tag="ACL73E_000989"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS0800976.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKPYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVAVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9137..10036
                     /gene="galU"
                     /locus_tag="ACL73E_000990"
     CDS             9137..10036
                     /gene="galU"
                     /locus_tag="ACL73E_000990"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGS0800977.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQDEGKDGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFARKFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(10103..10780)
                     /locus_tag="ACL73E_000991"
     CDS             complement(10103..10780)
                     /locus_tag="ACL73E_000991"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGS0800978.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYMTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRLYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(10764..11303)
                     /locus_tag="ACL73E_000992"
     CDS             complement(10764..11303)
                     /locus_tag="ACL73E_000992"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGS0800979.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(11315..12445)
                     /locus_tag="ACL73E_000993"
     CDS             complement(11315..12445)
                     /locus_tag="ACL73E_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGS0800980.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(12513..13211)
                     /gene="dapD"
                     /locus_tag="ACL73E_000994"
     CDS             complement(12513..13211)
                     /gene="dapD"
                     /locus_tag="ACL73E_000994"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGS0800981.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(13441..14352)
                     /locus_tag="ACL73E_000995"
     CDS             complement(13441..14352)
                     /locus_tag="ACL73E_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0800982.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(14417..16882)
                     /gene="pbp1b"
                     /locus_tag="ACL73E_000996"
     CDS             complement(14417..16882)
                     /gene="pbp1b"
                     /locus_tag="ACL73E_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGS0800983.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALVPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            17024..18280
                     /gene="tyrS"
                     /locus_tag="ACL73E_000997"
     CDS             17024..18280
                     /gene="tyrS"
                     /locus_tag="ACL73E_000997"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGS0800984.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(18358..20421)
                     /locus_tag="ACL73E_000998"
     CDS             complement(18358..20421)
                     /locus_tag="ACL73E_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS0800985.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(20423..20701)
                     /locus_tag="ACL73E_000999"
     CDS             complement(20423..20701)
                     /locus_tag="ACL73E_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGS0800986.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            20853..21701
                     /locus_tag="ACL73E_001000"
     CDS             20853..21701
                     /locus_tag="ACL73E_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGS0800987.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            complement(22040..22255)
                     /locus_tag="ACL73E_001001"
     CDS             complement(22040..22255)
                     /locus_tag="ACL73E_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800988.1"
                     /translation="MCYYVKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFS
                     FRGSVWGLVLALYHLLFIDKFVISNRK"
     gene            22322..22894
                     /locus_tag="ACL73E_001002"
     CDS             22322..22894
                     /locus_tag="ACL73E_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0800989.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGIYLAQLWDKNDAIPNNGRINF"
     gene            complement(23939..26197)
                     /gene="glgP"
                     /locus_tag="ACL73E_001003"
     CDS             complement(23939..26197)
                     /gene="glgP"
                     /locus_tag="ACL73E_001003"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGS0800990.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(26223..27755)
                     /gene="malQ"
                     /locus_tag="ACL73E_001004"
                     /pseudo
     CDS             complement(26223..27755)
                     /gene="malQ"
                     /locus_tag="ACL73E_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            28290..29561
                     /locus_tag="ACL73E_001005"
     CDS             28290..29561
                     /locus_tag="ACL73E_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGS0800991.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            29672..30964
                     /locus_tag="ACL73E_001006"
     CDS             29672..30964
                     /locus_tag="ACL73E_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGS0800992.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            30966..31808
                     /locus_tag="ACL73E_001007"
     CDS             30966..31808
                     /locus_tag="ACL73E_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGS0800993.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            32061..32861
                     /locus_tag="ACL73E_001008"
     CDS             32061..32861
                     /locus_tag="ACL73E_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGS0800994.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            32871..33857
                     /locus_tag="ACL73E_001009"
     CDS             32871..33857
                     /locus_tag="ACL73E_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0800995.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(34193..35134)
                     /locus_tag="ACL73E_001010"
     CDS             complement(34193..35134)
                     /locus_tag="ACL73E_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS0800996.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(35112..36875)
                     /gene="aspS"
                     /locus_tag="ACL73E_001011"
     CDS             complement(35112..36875)
                     /gene="aspS"
                     /locus_tag="ACL73E_001011"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGS0800997.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT        11180 a         7970 c         7029 g        10859 t
ORIGIN      
        1 agacttgata agaactctag agttagctcc ccatgttgaa ggtggctatt ttagacaaac
       61 aaaaaaagct tcagacacta taaaccttgc tggtaaggga agggcgcttt ataccagtat
      121 ttatttctta ttaagaagaa acgaatcctt cacattttca ccgattgaca gcagatgaaa
      181 tctggtattt tcatgcagga tccccactta ctgttcacat gatcacagca gatggtcact
      241 acgaagcagt cactttaggc ctggacatat ccaaagggca acaacttcac tactgtgttc
      301 ctaagggcac tatttgggga tcaacagttg ataaggatga tgctctggtt tcttgtcttg
      361 ttgctcctgg ttttgaattt gaggattttg aattatttga aagggtagat ctactggcga
      421 cctatccaga gcacaaggag atgattgagc gtttgaccag atactagtct tgataagcaa
      481 atttaatctg atttagcaat gttaggattt ctgataattg tgttataatg ttaccaatag
      541 gagataatag atgacaaaac aagtcttatt agtggatgat gaagaacaca ttctgaaatt
      601 gcttgactac catttaagta aggaaggctt ttctactcaa ttggtaacaa atggacggaa
      661 ggccttagct ttggcagaaa cagaaccctt tgattttatc ttgcttgata tcatgttacc
      721 acaattagat ggcatggaag tttgtaagcg gctgagagcc aaaggcgtca aaactccaat
      781 tatgatggtt tctgcgaaaa gtgatgaatt tgataaggtt ttggccttgg aattaggggc
      841 tgatgactac ctgaccaagc cttttagccc tagagaattg ctggcgcgtg tcaaggctgt
      901 cctcaggcga actaaaggag aacaagaagg agatgattca gataatatcg ctgacgattc
      961 ttggctattt gggaccttga aagtataccc tgagcgtcat gaagtctaca aggcgaataa
     1021 gttactgagt ttgaccccaa aagaatttga actcttgctc tatcttatga aacatcccaa
     1081 catgacactg actagagagc gtcttttgga acgtatctgg gggtatgact ttgggcagga
     1141 aacacgtttg gtggacgttc atattggtaa gttgagggaa aaaattgaag acaatcctaa
     1201 agcccctcaa tttattcgaa ccattcgggg ttatggttat aagttcaagg agttatagat
     1261 gaaacgctac cttcaatttt ggctagtcaa tctaagtgtt agcctcattc tgattgcagg
     1321 gatggcatta acttggatca gtaaaggcat cggtctcttt cttctagccc tttctttggg
     1381 acaaggtggc tactggctct tttgcctttg gaaatgggaa gttgcttttg agaccttgca
     1441 ccaacctctc ttgaccagta gtgaatactt tttagaaaaa gggcaagaag acttaaagtc
     1501 tttggctcag tatgtgtctg gcctaaaaac caaagtctcc caacaggatc agcaatacaa
     1561 ggacctagcc gaaacaatgg aggttcttct gtcgcaccta accatgggga cgtttttagt
     1621 ttccgctcaa ggtcagatgt tattatccag tcgctctctg cctcattatt ttcccgatgt
     1681 ggacggcgac ataagttcac ttgatgacct caaacggatg gatattcgaa atttagttca
     1741 ccaagccttt gatcaaaaaa caaggttaaa acaagaagta agtgggtttc atgagggtga
     1801 cttgatttta gaagtaacag cagttcccgt ttttagcccc acccaatctg tggaagctgt
     1861 gctcgtcttg ctatatgatt taacaacgat tagaacttat gaaaagttaa atttagcctt
     1921 tgtctcaaat gcctcccatg aattgaggac accagttact tcgattaagg gctttgctga
     1981 aaccattaag gggatgtcag ctgaagaaga agcgctcaag gatgactttc tagacattat
     2041 ttacaaagaa agtttgcgtc ttgagcatat tgttgagcat cttcttacct tatctaaggc
     2101 tcaacaaatg cctatacaat ggacgaccct ttctttggca gaatttgtac aggatttgac
     2161 tcaaagcttg caacctcagc tcaagaagaa ggatttacag ctaaaggtgc aggtgccaga
     2221 tgatgtcacc ctcgtatcag atagtcaatt actttcccaa atcttactca atcttttatc
     2281 caatgccatc cgttacactg aacaaggggg aaaaattgag gtcaagaccc aaaaggtgaa
     2341 cgaaggcatt aagatttctg tatcagatac agggattggt attagtcaat tagagcagga
     2401 tcgtattttt gaacgttttt accgagttaa taaaggtcga agcagacaaa ctggtggcac
     2461 tggtcttggc cttgccattg tcaaagaact cagtcaatta ttaggtggcc aagtcacggt
     2521 gacgagtcag cttggcagag gcagttgctt cacgattttt cttcctaacc aatctttcgc
     2581 acaggactaa taatttttaa agctattttt aggagcagcc atttttcaaa agtggctttt
     2641 tttgattctt tacacaatct ttacatgaat cagggataaa cctttacaaa gacttgttag
     2701 actataaatg tagtaagcct acacaagaaa aatacataga gataaaggtg attattatga
     2761 aattcaaaaa aatgcttact cttgcagcca ttggcttatc aggatttggg cttgttgcct
     2821 gtggcaatca gtcagctgct tccaaacagt cagcttcagg aacgattgag gtgatttcac
     2881 gagaaaatgg ctctggaaca cggggtgcct tcacagaaat cacagggatt ctcaaaaaag
     2941 acggtgataa aaaaattgac aacactgcca aaacagctgt gattcaaaat agtacagaag
     3001 gtgttctctc agcagttcaa gggaatgcta atgctatcgg ctacatctcc ttgggatctt
     3061 taacgaaatc tgtcaaggct ttagagattg atggtgtcaa ggctagtcga gacacagttt
     3121 tagatggtga ataccctctt caacgtccct tcaacattgt ttggtcttct aatctttcca
     3181 agctaggtca agattttatc agctttatcc actccaaaca aggtcaacaa gtggtcacag
     3241 ataataaatt tattgaagct aaaactgaaa ccacagaata tacaagccaa cacttatcag
     3301 gcaagttgtc tgttgtaggt tccacttcag tatcttcttt aatggaaaaa ttagcagaag
     3361 cttataaaaa agaaaatcca gaagttacga ttgatattac ctctaatggg tcttcagcag
     3421 gtattaccgc tgttaaggag aaaaccgctg atattggtat ggtttctagg gaattaactc
     3481 ctgaagaagg taagagtctc acccatgatg ctattgcttt agacggtatt gctgttgtgg
     3541 tcaataatga caataaggca agccaagtca gtatggctga acttgcagac gtttttagtg
     3601 gcaaattaac cacctgggac aagattaaat aaaatgtttg ctccataaat ctctaaagag
     3661 atgcagacgt ttcatcgtac aataagataa agaaggcaag tagggaggtg tcgtatctcc
     3721 cttactttct tcactagaaa ggacaagatg tgacaaaaca agccttcaaa gaagcagttt
     3781 ttagggcaat ttttttcatg agtgcaacag tagctgttgt agctattttg ctaatctgtt
     3841 tctttatttt tagtaatggc ttacctttca tagctaacta cggctttgcc cgttttttat
     3901 taggcagtga ttggtcgcca acgaacattc cggcaagcta tggtatttta ccaatgatcg
     3961 ttggttcctt attaattacc ttaggagcga ttgtgattgg ggtgccaaca ggcatcttga
     4021 catcggtgtt tatggtttat tattgtccaa agcccgtcta tggcttctta aaatcagcta
     4081 tcaacttgat ggcagccatt ccatctattg tttatggttt tttcggccta caattattgg
     4141 tgccttggat tagaagcttt ttaggaaatg gcatgagtgt cctaaccgct tcgttactat
     4201 taggaataat gattttgcca actattatca gtttgtcaga atctgctatc cgaacagttc
     4261 ccaaaacgta ttattctggt agcttggctc taggagctag tcatgaacgg agtattttta
     4321 gtgtcatctt gccagctgcg agatctggta ttttatcagc agttatttta ggaatcggtc
     4381 gcgcagtagg tgaaaccatg gcagttatct tggtggcagg caaccagccg attattccaa
     4441 gtggactctt ttcaggaacc agaaccttaa caaccaatat tgttctggaa atggcttacg
     4501 catcaggtca gcatagggaa gcccttattg caacctcagc agttctcttt ttccttattc
     4561 tcttgattaa tgcctacttt gcctacttga aaggaaaatc atcttatgag taaatacctg
     4621 ctaaaacttc tcgtttattg tttttcagct ttaacctttg gctctctctt tttaatcatt
     4681 ggttttatcc tcatcaaagg cttacctcat ctaagtctat ccctcttttc ttggacttat
     4741 acttctgaga acatttccct tatgccagcg attatttcca ccgttattct ggtctttggt
     4801 gctcttcttt tagccttgcc catagggatt tttgctggtt tttatcttgt ggaatataca
     4861 aaaaaagatt ccctttgtgt taaaatcatg cgattggcct cagatacctt gtctgggatt
     4921 ccttccattg tttttggtct gtttggcatg ctcttctttg tagtcttctt aggttttcaa
     4981 tactctctgt tatcaggaat cttaacctca gtcatcatgg tgttgccagt cattattcgc
     5041 tcaacagaag aagccctttt atctgttagt gatagcatgc gtcaagcaag ttatggactt
     5101 ggggcaggta agttacggac tgtttttaga attgttctac cagttgccat gccaggtatt
     5161 ttagctggag tgatactagc tattggccgt atcgttggtg agacagctgc cctcatgtat
     5221 acattaggta cctctaccaa tacgccaagt agtctcatgt cttcaggtcg ttctctagcc
     5281 ctgcatatgt atatgctgtc aagtgagggg ctacatgtca atgaagccta tgctaccggt
     5341 gtgattttga ttattactgt tttaatgata aatactctat caagcttatt atctcgaaaa
     5401 cttgtgaaag gagcttccta gtatgggaac attttcagtt agacacctag acttatttta
     5461 cggggatttt caagccttaa aaaatatttc gattcaatta ccagaaaggc agattactgc
     5521 cttgataggc ccatctggtt gtggcaaatc aacttttcta aaaaccctta accggatgaa
     5581 cgatttggtt ccttcttgcc atattgaagg ccaagtcctc ttagatgagc aagatattta
     5641 tagtagcaaa ttcaacctta atcagctacg taagcgtgta gggatggttt ttcaacagcc
     5701 taatcccttt gccatgtcta tctatgataa cgtggcttat ggcccaagga cacatggtat
     5761 tcgagacaaa aaacaattag atgccttagt ggagaaatct ttaaaagggg cagccatttg
     5821 ggaagaagtc aaagatgatc ttaaaaagag tgccatgtcc ttatctggcg gtcagcagca
     5881 acgcctttgc attgcgcgag ctttagcagt agaacctgat attctgttaa tggatgagcc
     5941 gacttcagcc ttagacccta tctccacttt aaaaattgaa gacctcattc agcaactaaa
     6001 aaaagattat acgattatca ttgttaccca taacatgcaa caagcttcac gtatttcaga
     6061 taaaactgct tttttcttaa caggagaaat ttgcgaattt ggagataccg ttgacgtgtt
     6121 taccaatcca aaagatcagc gcacagaaga ctatatttca ggacggttcg gataaggaag
     6181 gaaaaaccta tgagaaatca atttgactta gaattgcatg aattagaaca atccttttta
     6241 ggactagggc aacttgtcct tgaaacagct tcaaaagcct tactggcctt agcctccaaa
     6301 gacaaggaga tggcagagct aattatcaat aaggatcatg ctatcaacca aggtcaaagc
     6361 gctatcgaat tgacctgtgc ccgtttgttg gccttgcagc agccacaagt gtctgacctt
     6421 cgatttgtga ttagcatcat gtcttcttgt tcagaccttg aacgtatggg agaccatatg
     6481 gcaggcattg ccaaagctgt tttgcaacta aaagaaaatc aactagcccc tgacgaagaa
     6541 cagttacacc aaatgggtaa attatccctc agcatgctag ccgatttatt ggttgccttt
     6601 cctttgcacc aagcctcaaa agctattagt attgctcaaa aagatgaaca gattgaccaa
     6661 tattattatg ccttatcaaa ggaaatcatt ggacttatga aagaccaaga aacctcaatt
     6721 cccaatggaa cacaatacct ttatatcata gggcatctgg aacgcttcgc tgattacatt
     6781 gctaacattt gtgaacgcct agtctaccta gaaacaggag aactagtgga tttgaattaa
     6841 ttcaactaat ccttaaaaga gaagagtacg attaagtgct cttttttatg gttgtaaaaa
     6901 agttcatttg aacaatttaa gcagtgtaga tagtgaggag ctgtttcaat tctatcgtga
     6961 acgagggaat gctgaaaact ttatcaaaga aaggaaagca ggattctttg gggataagac
     7021 agatagttcg accatgatta agaatgaagt acgtatgatg atgggctgtc tggcttataa
     7081 tctctacctc tttttaaagc agctagctgg tgatgaagta aaggccttga ctatcaagcg
     7141 ttttcgacgt ctcttccttc atattgccgg aaaatatgtc tctactgcta gacgacatat
     7201 tctcaaattc tcaagtctat atgcctcttc aaaacagttt caagccttat ttgatacaat
     7261 ctgccagata aatctgatac tccctgttcc atatagagct agagggcagg ggaaaacatg
     7321 cctaacagaa taagtcacct tattttaaaa atcgagcatc aaaccaaggg aggagtctgc
     7381 ccttttttag gaaaaaatca agacaaatct cctcaattat gtctcgaaca tcagaaatta
     7441 agcaaaatca ccagaaggac agtatttcaa ctagcttttc tggtaatttt tgaactgtgt
     7501 agttcgttag tgccagatat gaataatttg ggatgataaa tctttcttcc tcaggtagcc
     7561 tatcataata ctcttcaaaa atcttatcaa aacactctct ttcttttggg cgatagtttc
     7621 atcttcgtat gtaggagtcc tcatcaagaa atacttcaat tctaggtatt ccttatccaa
     7681 ctctatataa cttggcatca acttgtaatc ttcaaccccc aaacgttcag cgatatattt
     7741 taactttgtt agtgttggtc tggattctcc attttcaatt ctaattaatt gacggatact
     7801 taattcagac tcatcaccac aaaattctga acgactgatt tttttagcca aacgtaatct
     7861 tttaattttt tcgccaaact ttcgcaacct acaagaacct cctgagttgt ttacctctat
     7921 ttatagcata tactgaatca aactatctat cagatttctt ctcactttaa ctaaagacta
     7981 agagtttatc ccttcatctc gatctttgtg tatttttcca ccatacccca gtaatgcaag
     8041 tgcaaaatcc cctagaatat gatataataa gagaaagaaa tctatcaagg aggaaatcat
     8101 ggaaaaacaa accgtcgccg tcttggggcc tggttcttgg ggaaccgccc tttcacaagt
     8161 cttaaatgac aatggacacg aggtacgtat ttggggaaat cttcccgagc aaatcaatga
     8221 aattaataca caccatacta ataagcccta ctttaaagat gtcgttctag acgaaaatat
     8281 cattgcctac accgacttag cagaaacatt gaaaaatgtg gatgcgattt tgtttgttgt
     8341 cccaacaaaa gtgacacgac ttgttgccca gcaagttgca caaaccttgg accataaggt
     8401 tatcatcatg cacgcatcaa agggattaga acctgatagc cataaacgat tatcaaccat
     8461 tcttgaagaa gaaattcctg aacatctccg tagtgatatc gtcgctgttt cagggcctag
     8521 tcatgcagaa gagaccattg tgcgtgacct aactttaata actgctgctt ctaaagattt
     8581 acaaacagct caatacgttc aggagctatt tagtaatcac tacttccgac tttataccaa
     8641 tacggatgtt atcggggttg aaactgctgg tgctcttaaa aatattattg ctgtcggtgc
     8701 tggagcttta catggtcttg gatttggtga taatgctaag gcagccatca tcgctcgagg
     8761 tttagcagaa atcacccgcc taggggtagc actcggggcc agtccattga cctatagcgg
     8821 cttatctggt gtgggagatt tgatcgtaac gggaacttcc atccactctc gtaactggag
     8881 agctggagat gctctcggac gaggagaatc cctagctgat atagaagcta atatgggcat
     8941 ggtaatcgaa ggaatttcaa cgactcgagc agcctatgaa ctagcccaag aacttggagt
     9001 ctatatgccc attacacagg ctatttacca agttatttat cacggaacca atatcaaaga
     9061 tgccatttat gacatcatga acaatgaatt taaagcagaa aatgagtggt cttaaccctc
     9121 tatagaaagg atttttatga catcaaaagt tagaaaggca gttatccctg ctgctggact
     9181 aggaactcga tttttaccag caaccaaggc ccttgccaaa gaaatgttgc caatcgtaga
     9241 caaaccaact atccagttta tcgtggaaga ggctctcaaa tcaggtattg aagatattct
     9301 agttgtcact ggtaaatcaa aacgttctat tgaggaccac tttgattcaa actttgagct
     9361 tgaatacaat cttaaggaaa aaggcaaaac ggatttgtta aaattggtag atgaagcaac
     9421 tggcatgcgc cttcatttca tccgccaaac tcaccctcgt ggtcttggag acgctgtctt
     9481 acaagccaaa gcttttgtag gaaatgaacc cttcgttgtt atgctgggtg atgacttgat
     9541 ggacatcaca gacgagaagg ccgttccttt gacaaaacaa ctgatgaatg attacgaaaa
     9601 gacacacgca tcaaccattg ctgtcatgcc cgtaccacac gaagacgttt catcatatgg
     9661 agtcattgct cctcaagacg aaggaaaaga tggtctttac agtgttgaaa cctttgttga
     9721 aaaaccagct cccgaggaga ctccaagtga tttggcaatc atcggtcgct atctactcac
     9781 accagaaatt tttgagattc tcgaaaagca agctcctggt gctggaaatg aaatccaact
     9841 tactgatgca atcgatactc ttaataaaac acagcgtgtt tttgcccgta aatttacagg
     9901 agctcgttac gacgttgggg ataagtttgg ctttatgaaa acatctattg actacgccct
     9961 caaacatcca caagtcaaag atgatttgaa gaattacctc atccaacttg gaaaagaatt
    10021 gactgagaag gaataaaata aaaagataag gttcaaaaaa tgccttatct tttttcatta
    10081 cacaaatttt ctttcaactt cgtcacattc ccattccctt gtagaaaagc aaaatggcga
    10141 gtcctacgaa caagactacc gctcctaatc tctggctggt gttatacagc cgtttttctc
    10201 ctctaactgg aaagataact gctagaaatg cgccaccaac tgctccaccg atatggcctg
    10261 ctaggctgat ccctggaatc agaacacttc caataatgtt aaccacaaaa agtgtcatat
    10321 aggattggcc caactgctgg atataaggat tacgcgttgc atagcgaaga atgataatcg
    10381 cggcaaatag cccataaaga gaggtagagg cgcctgctgc taaggattta ggactaaata
    10441 caaaaacaaa gagattgccc atcattcctg ataagagata gagaaaaaag aactgcttag
    10501 agccgaaaat ctcctctacc tgccttccaa gataataaag tgaaagcata ttaacaatga
    10561 aatgttccca cccaatatga acaaaaatgg cagacaagag acgccaaacc tgctcgggaa
    10621 agaggcgaat agctggccca tacatggctc caaatcgaaa taatgtatct gccctgtcaa
    10681 agtttccgcc tgcagtgacc aacattagta aaaataccaa ggccgtcact aagaggaaga
    10741 aactcgtcac agggtaacgt ctatcaaaga tttccttcat caattaatac ctcctgaaca
    10801 ggaatatcat ggttttcagg tataaagtcc tgaatttgac aaggatgaac cgtactcaaa
    10861 gtatgaccag aaaaatgttc cagatagcgg tcataataac ctccaccata tccaatccga
    10921 tatccatccg tcgtaaaagc caggccagga acatgaatca aatcaatctg agatacatcc
    10981 accacttcca aatctccctg tggctccagt aaggcaaagg cagtttttac caactgctgc
    11041 agatcataga ctacaaagtc catgcgcccc ttgggataag ttttgggtat taaaaccttc
    11101 ttgccgtcct tcagcgcctg ctcaatcagt tcccgcgttt gaaactcatg agaaaaagag
    11161 aggtaggttg cgatgacctt ggcttcttga taaaaggggt gttgtaaaat tcgctcggtt
    11221 aaagcttggt ctatagcctg tttttgttct tgagataaag ccttcatttc atgcaagact
    11281 tgcttgcgta attccgattt catagacaag ccctctattc tgctgccttc tttttcagga
    11341 aactagacac cgcagccacc ccaatagcta agacttcttc cttaggactc atttgagggt
    11401 gatgaagagc gtagggacta tcgataccta gccaaaacat cacgccatca acctttgaaa
    11461 ggagataacc aaagtcctcg cctgtcatag caggttcgat atcaatcaac tcgattccgt
    11521 ctttctcgtc aaagaagtcc atcagttcac gcgccaaggc tggattgttc tcaacaggta
    11581 ggtatccacc ttgtttgagt tccacttcga cttccatatc aaaggcagct gcaacccctt
    11641 ctgcaactgt ttttaccctc ttttgcacca agagactcat gtcctgtgtc aaggcacgaa
    11701 tagttccatg taaaaaagct gtgtctgtga tgacattgtt ggtggttcca gcttgaaaaa
    11761 cgccgaaggt caccactgct ccctcgattg ggttgacatt gcggctaaca actgactgca
    11821 cttgggtcac aaagtaacta gccgccacca aggcgtcatt ggcttcatga ggaaaagctg
    11881 cgtggccacc tttgcctttg aaacggatct tcacctcgca agttcctgca aagagtgtat
    11941 gagtattagt cgcaatctgg ccgactttca aatctggacg aacatggaga ccatagaatt
    12001 ggtttggcaa ccaatctcca aaagcaccag cctcatacat gagcatacca ccagcttcat
    12061 tttcttcagc aggctgaaat agaaagagca gattattttt aggttgctcc tcaagggcgc
    12121 gctcaagaca gcctaaggca atggtcatat gaaaatcatg gccacaggca tgcatgcgac
    12181 cttggtgttg agaagcaaaa ggtagacctg tttgttcgac gataggcagg ccatcaatat
    12241 ctgtccgcca accaatggtt cgctccggct gacttccctg caggtagacc aaaatccctg
    12301 tccgccaagt acgaatttga acaaaatcct tgcccgtagt caatttctca atcacatcca
    12361 gcaaataagc ctgagtcttg aactcctcca agccaatctc tggtatctgg tgtaaatctc
    12421 gtctagtctg aatcaaatct aacatctatc tgtcctccga tatagcagaa agaggctgga
    12481 aaaagggttc cgcctctttt ttacttttac aattacaagg tacgaagcgc atcctctagc
    12541 gctgtttttt gttgagtttg ggcatcaatt tctttgatga tacgagctgg aacacctgct
    12601 actaccacgt tttctgggac atcttgggta acaatagctc ctgctgcgac aactgaacca
    12661 ctaccgattt ggactccttc gataaccact gcattagcac cgataagaac attgtctccg
    12721 acacggactg gttcagcact agctggctca atcacacctg ccaaaactgc acctgcacca
    12781 acgtggctat tttttccaac gatggcacgg ccaccaagga tggcacccat gtcaatcatg
    12841 gttccagcac cgatttcagc accgatattg ataacagctc ccatcatgat aacagcattg
    12901 tcaccaattt ccacctggtc acggataata gcacctggct cgatacgagc gttgatagca
    12961 cgcttatcta gcaaaggaac tgcagaatta cgagcatctt gctcgacaac ataatcttga
    13021 ttttctacca aaccttcaag aagcggagcc acgtccttcc agtctccgaa taggacattt
    13081 cctagtttga caacagagct aggcacagca gttgcgagtt gcccctcaaa ggttactttg
    13141 acactggttt tcttttcagc attggcgata aattggataa tttcttgagc gttcattttt
    13201 gtagcagtca taggtgcctc ctggttcgtt ataatgatac ctattctacc aaaaaaggcc
    13261 tcaaatttga aacctttttg tctgttttta ggtatgattt tttagggatg tgagataaaa
    13321 cgtgctgtcg gtaaaagcaa gcccctaccg atacaaccta aaaacactct tcacaactat
    13381 ctccccgtgt tttattgact attctagtat agcacacttt tagaattaag aaaagacttt
    13441 ttatctactt tctttcgctt cttctataga caaaaatatc atgggtaaaa taatcaaggc
    13501 tatagctaga aggagggacc aatccactac taatcctaag aacaaaacac tcaagagagc
    13561 agaagagaga ggttcactgg cactgataac ggaaaccacc aaaggagaaa ccaaggacac
    13621 agccttcatg gaaatgaaaa aagcaaaagc cgttccaaag aaagcgataa tgaggcaaat
    13681 caagatactc caaatatcaa gagtaaagga aagctgataa accggcgaga ggacattgct
    13741 aaacaaacct gccaaaatca tcccccaccc aaccgtagga acaaaaccat aacgcttagc
    13801 aaaaggttgg ggcaagataa cattaaacat aacacccatg gcactcagca aacctgttat
    13861 aagagctagc ggcgtcatgg ataactgaga gaggtctccc tttgtcgcca tcaagcaaac
    13921 acccagcatg gcaaccaaaa catagaaaac agcgcttttt gacgctcgtt tttgataaac
    13981 caagcgattg taaaagagga taaagacagg gctaataaac tgtaaaatag ttgctgtcgt
    14041 agcatttgag tattctacac agagatagaa aaaatactga actgaaaaaa tccccaaaat
    14101 agcataggct aaaaagggca ggtaattttt cttgtctcgc caaatatcta gcacttgcga
    14161 ttttaattgt attgcagacc aaatgagtac aagactccct gccagtgtca aacgcataga
    14221 ggtaatccag cccgaagaca cctgataatg agtaaagaag tactctccta aaattccaca
    14281 gattccccat attaagccgg ataggagcga ataaattttt ccgttaacaa tctttttctg
    14341 atactgattc atacccttat tgtaacacga aaggaaaaaa gtggcaatcc attgattggc
    14401 cacttcattt agagaattat cgtctcgccc ttgaagaaga aggtcgtgta gtacttgagt
    14461 tactgctatc gctagaacta ctacttgaac tgctggagct ggatggagtt ggtagactcc
    14521 ccacaatact agaccaagca ttctgataat ccgcatcact tccgccaata gcaaagcgat
    14581 aacttgtcgc tggcgctcct gacttattag cccaatagct ggtaacagtc gaacctgtga
    14641 cctctacttc ttttccttca acagaaacct tccctggttt ttgacctgtt gatttcaaga
    14701 cttccgattt cactacacta ggaactaaag caaagcgctc gttcccccaa atgcttgggg
    14761 aagcttgctg aatcgcattt actagatgag ccatgtaatt agagttatta gaataacctg
    14821 ctctacgtga caatgaatga ttatcatcat gcccaatcca gccacctagg gttaatctag
    14881 gtgtcgaaag catgagccac atattttcgt cttggttggt tgtaccagtc ttcccaatcc
    14941 aatctgcatt agccagagta ggatttaaag aagtcaggtt agacttgaag gttgttgtca
    15001 cacgagagga tagaacttct cgtagcaatc cctgcataat cgtcgcagta gcttttgaat
    15061 agacttgaac cggtttatcc tgatactcat acaccactct accatctgct gcttcaatct
    15121 ttgaaatcac atgcttctga tgataaactc cattattagc taaggtctga tagccattgg
    15181 tatgctgggc aactgtgact tcaataccac cacccattgg caagctctca ataccgtact
    15241 caggaatctc gtaacccatc ttttccatat aacccttgac atcaacaccc ttttcacgga
    15301 gcatacgata ggtccagtaa gcagggatat tccatgaata gttcagagct tctcccaagg
    15361 tcatcattcc tgttcccttg ctattagcat acataatcgg attgccatta gcaaagtttg
    15421 ttggatagtt agatagaatc gtttcacttc ccatcaagcc ctgatcaata gcaataccgt
    15481 aggccagcaa gggcttggta gtagaagctg gcgaacgttt ggtatcaaag gcatgattat
    15541 tttgattttc ttgataatta cgaccaccta caaagcctag aatagcacct gtttggttgt
    15601 ccatcaagac attccctact tctacacgac ctgttccatc gtctaaaaga tagccataat
    15661 cagcaaccgc actttgcatg gcagaatgaa ttttctgatc tatggtagta gtaatcttat
    15721 aaccaccatt ttcaatttcc ttggctgcca aatctcgata aaacttctga gttgcctcat
    15781 ttttcaactc cttagcggag acattgtctc tctgagctag atagtcatac atacgttctt
    15841 gagcttctgc caaagttgta aagtataaat agtctcgtga aattcctgta acagtgcccg
    15901 atggtaaaaa gtcctgttta aggtcataat ccttgtactg agaatactcg tctttgctta
    15961 atgcacctgt acgatacata ctgtaaagaa ctgccttagc ccgtcttaag ccaatttcta
    16021 ggtcttcatc actcttcaac tccccagtat tttcataagg agagtaagta atgggactct
    16081 gtggaagtcc tgctaaaaat gctgcttgag gaacagtcaa ctgactggca tctacaccga
    16141 aaattccctc agctgcttgc cgagcccctg caatattctg tcccttatta tttcggccaa
    16201 agggagccac attgagatag gtcgttaaaa tctcatcttt attcatggcg cgttccaagg
    16261 caagagcatc cacaatctct gccgccttac gagccaaggt cggcgcatcc ccaaccacct
    16321 gctgtttaat tagttgctgg gtcaaggttg aacccccact agaggaaccc aaacctacaa
    16381 atttccccaa ggtcgcacga atcaccgcct tgggtactac acccttatgt tctttaaagt
    16441 gttcatcttc tgtcgcaatg atagccttct tcagattttc cgaaatttgc tcagatgaga
    16501 tagaagtgcg caacaaatca ctctctatgg aagcaatcac cgtcccgtcc gaataggtaa
    16561 tctctgaaat agaagagatg tccttgacct gattcaccaa ttcttctgtc tgaggcaccc
    16621 gaaccttgtc aaataaggcc actccgtacc ccaaagcaat cccagctccc aacattcctc
    16681 ctagaaaacc gagtacaaag agtaagttaa ataaggcttt tatactcagt aaaatagctg
    16741 ggaaaatggc tgacttatct aaggttttag attttttggt acttgaacct ttcttgccag
    16801 gtctagctga ttttttattt ttttgttttt gctggaaaaa ttccagcatt tttcgtttta
    16861 attcatttaa ttgattttgc atggatttcc tcactctatc tattatacca caaaagggaa
    16921 attttcaata aaatagccac tttcttccct attctgctag gctattgccc aagtttgtga
    16981 tacaataggt agaaacaata attttaaaaa ggagaaaaga cacatgcaca tttttgatga
    17041 gctaaaagag cgtggtttga tatttcaaac gactgatgaa gaagctttgc gtaaagccct
    17101 agaagaaggt caagtttctt attatactgg ctacgatcca actgctgaca gccttcacct
    17161 aggccacctt gtcgcaatct tgacaagtcg tcgcttgcaa ctagcaggtc acaaacctta
    17221 tgcgctcgtt ggcggtgcta caggtctcat cggagatccg tccttcaaag atgctgaacg
    17281 tagtctccaa acaaaagaca cagtagatgg ctgggtcaag tctatccaag gacaactttc
    17341 tcgttttctt gactttgaaa atggcgaaaa caaggctgtc atggtcaaca actacgactg
    17401 gtttggcagc atcagcttca ttgacttcct ccgtgatatt ggaaaatact tcacggtcaa
    17461 ctacatgatg agtaaggaat ctgttaaaaa acggatcgaa acaggaattt cttacactga
    17521 gttcgcttac caaatcatgc aagggtacga cttcttcgtc cttaaccaag accataatgt
    17581 cactcttcaa atcggtggtt ctgaccagtg gggaaatatg acagctggta ccgaattgct
    17641 tcgtcgtaag gcggacaaga ctggtcacgt tatcactgtt ccactaatca cagatgcaac
    17701 tggtaagaaa tttggtaaat cagaaggaaa tgccgtctgg ctcaatcccg aaaagacttc
    17761 tccatacgaa atgtaccaat tctggatgaa cgtgatggac gctgacgctg ttcgcttctt
    17821 gaaaatcttt actttcttgt cacttgatga gattgaagat attcgtaaac aatttgaagc
    17881 agcgccacac gaacgcttgg ctcaaaaagt cttggctcgt gaagttgtta cacttgttca
    17941 cggagaagaa gcctacaaag aagcacttaa catcactgag caactctttg caggaaacat
    18001 caaaaacctt tctgtcaaag agctcaaaca aggacttcgt ggtgtgccaa actaccaagt
    18061 acaggcagac gaacataaca atatcgtgga actgctcgtc tcatctggta tagttaactc
    18121 aaaacgccaa gcccgtgaag acgtccaaaa cggagccatc tacgtaaacg gcgaccgcat
    18181 ccaagacctt gactatgtct tgagtgacgc tgataagtta gaaaatgaac tgactgttat
    18241 ccgtcgtggg aagaaaaaat actttgtatt gacttactaa actattcaac atttatctat
    18301 aaacaaagga gttaacctcg agaaaggtaa ctcctttttg ctgttaataa ctctcatcta
    18361 tctattttta atagacaagc tacgcaagac aatgcgcaag gttgttagat tatgtaagat
    18421 agagagattt gaaggactga accaattaaa taagccaaag ccaatcaaac tactatttac
    18481 gacaacggta tcttgaatat ttttcttgat gagtgtttgc aaagatgatg ataacgaatc
    18541 caactcttgg aagaaatcca aacgattatc taacaataag atatcactca tctgcttaga
    18601 aatatctgca ctctcattca tcaccacacc gatatctgat agagttaaag ccgctgagtc
    18661 attcaatcca tctccaacca tcaaaatagt gtgacctgct ttctgcagtt tctctactaa
    18721 ctcaaatttc ccatcaggtt tcaagtctgt atagacctga tcaaagggca aatctttgac
    18781 taattcctct gtcctaatca aggtgtctcc tgttgccaga atcaattttt tcccctgtgc
    18841 cttaagttta tccaaggctg tttttgcttc ttttctcaaa ggagtatgaa tgcagaacat
    18901 tccaatcaat tcattttgat aagccaagaa taagagattg tagtgactct tgtactcttc
    18961 aattaaagca ttttgttctg aactgatatg aatctgctca tcctgcatca agacataatt
    19021 cccaataaga actggttggc catctatatg agatttgatc cccttgcttg cgatatattg
    19081 gagtttccca tgcatttcct catgttcaat tccctctatc tcagcttgct tgacgatggc
    19141 attagcaata ggatgataaa tgtgttcctc aagacaggca ctgattctga gaatatcttc
    19201 ctcactatag tctccaaaag gtaacacctt ttcaactata ggataactag ttgtgattgt
    19261 tcctgtctta tcaaacaaga aagtatcaac ttccagatat ttctccagaa catctccatc
    19321 cttaatcacc atttcacggt tcaacccctc cttgataact gtcaaataag ctacaggagt
    19381 agagattttc aaagcgcagg agaaatcgac caataggaaa gaaatagcct tagaaaaaga
    19441 acctgtcaat aggtaagtca gcccagcccc caagaaatta tatttgacga ctttatccgc
    19501 catcttgatg aaatagcgtt gtttcgtttt cttgttttct tcagatttct tcatcaactc
    19561 aatcagctgt aaaatacggc tgttcatctg attatctgtt acacgaatgc gtaactctcc
    19621 agtttctaat actgtatttg cacaaaccaa atcagactct cttttttcaa ctggaaaact
    19681 ctctcctgtc aaggaacttt cgttgaccat acctaaacct gaaactactt gcccatcaaa
    19741 cagaatttca tttccttgag ataagatcaa gacatctcct atttgaacat cggaactctt
    19801 tatactaaca accgtatcgc cctgtactag gaatacatcg ctctcttttg caagaagact
    19861 ctgttctaaa tctgttgcag tttttttcaa ggaccactga tctaaatgat tccccaaatc
    19921 aagcataaac atgatattgc tagctgtctt ggattggttc ataaacaaag acaataaaat
    19981 agccgaacag tccaagactt ccatagttag ttccttacgc gctagtgttt gataggcttc
    20041 tctaatataa cccaaagcct gataacaagt ccatatatag cgaataggat acggcacaaa
    20101 actacgaaaa agtacacgct taaccgctgc acctgaaaca atagaataag cactctcttc
    20161 tctacgaatg ggaagagtca tcaactcaga aactttccct ttatcaattc tttttaaaaa
    20221 ggcttctgca ttatctaata cagaaaagcc ttcttttatg cgtagagtaa agtgctgttg
    20281 atccatgtaa aactggatag actcaatccc cttttcatct ctcgccaagg aacgaagata
    20341 gtcttgaata tccaaggtaa gtgaaaaaga agatgatagt cggatatgtt ggtatcctct
    20401 atgtagcact ttaaaagaca tattattcac ctataaggct atctaattgc tcttcttttt
    20461 tctcttgctc gtacaaatat ttggcatctt gcaagacatc gtctccatgt tgcttcacaa
    20521 cagaaacaga tgcatctagc tcgtctttca acttgtaagc cttagccaaa gctttagaat
    20581 aacctttttt agcttcctta cttgctaaga ttttcaaacc aagggtacca aatgcgacac
    20641 cacccaaaaa taatgaagat tttttcgcaa cttttgcaac ggttaatact tcttttaaca
    20701 tacttatttc ctccttatca ttattatata gcaatttaga tataaaagca atttcattct
    20761 ataaattgga gaattagttt tatttctact gaatctccca tctacttatt cctaaagttg
    20821 ctttcatttg cctcttttga tacacttaaa ctatgaatac aaatctcaag cccaaacttc
    20881 agcgttttgc ttctgcgact gcctttgcct gtcctatctg tcaagaaaat ctgactctgt
    20941 tagagactaa tttcaagtgc tgcaaccgtc attcttttga cttggcgaaa tttggctatg
    21001 tcaatctagc acctcaaatc aagcaatctg ctaactataa caaggaaaat tttcaaaacc
    21061 gtcaacaaat cctagaagcc ggcttttacc aagctatctt agatgctgta tctgacttgc
    21121 ttgcaagctc aaaaactacc acaacaattt tggatatcgg ttgtggtgaa ggattctatt
    21181 ctcgcaaact acaagaaagt cactctgaaa aaactttcta tgcctttgac atctccaaag
    21241 attcagtcca aatcgctgct aaaagtgaac ccaactgggc agtcaattgg tttgttggcg
    21301 acttggcacg acttcctata aaagacgcta acatggatat tctgcttgat atcttctcac
    21361 ctgccaacta tggagaattt cgtcgcgttt tatccaaaga cggtatcttg ataaaggtta
    21421 tcccaactga aaatcacctc aaagaaatcc gtcaaagagt acaggaccag ctgacaaaca
    21481 aggagtattc taaccaagat atcaaggagc atttccagga acactttacc atcctatcta
    21541 gtcaaactgc ctctctgact aagactatca cagcagaaca actccaagcc ctactcagta
    21601 tgactcctct cctctttcac gttgaccaga gcaagattga ctggagccaa ctgacagaga
    21661 ttaccatcga agcagagatt ttggttggga aagcattcta aactagactt cccaaaggta
    21721 taaaacttac cgaaaatctt caatattata aaaacgcata agaacaggta cacaaacctt
    21781 aatcttatgc gttttgttat agtttccata cacattaagg ggaaatagtt gaaatcagtt
    21841 ctcttaataa ccattgaata ccatatacta catttacccc aaatatgata taggccgtat
    21901 aaatcaagta tttcgatttc tcccgtctca aagaataaat cttgtacaaa atagataaat
    21961 ttaaaataat aaataataga gacaaaatct tcctccaaaa tcaatattaa aagtagccag
    22021 tcaatcatag ttctaatctt tattttcgat tcgaaattac aaacttatca atgaacaata
    22081 agtgatataa ggccagtacc agaccccaaa cgctaccacg aaaagagaat tcttgatgat
    22141 tgagagtaaa caaatcatgg ttaccaatat agaggcaggt caaaataaca aataaaatcc
    22201 aaaataaatc cgtccattta tattttgaaa aatatttttt aacataatag catatttttt
    22261 tgactataat aacagtatat gataaaatgt aagcagatac aaataaaaag gagaaaagct
    22321 catgaacaaa ttaatgaaat ttatttcggt ttttttgacg tcaattgtgt taattgtatc
    22381 agcgattcca agtgtttcag ctgtatacgc ttctgaacaa gtatcacaaa ttgaaacaaa
    22441 tatggaactt caacctgtca cttctctaac agaagaacaa atcaatacac ttgcaaacga
    22501 aatccaatct tttcatccag acgtctcaca acaatggatc aaagaagtaa ttaaccgaca
    22561 attacaaggc gattatacaa tcccacctac atactctcca tttagagcag cttggcaagg
    22621 tattacagtt aatcaaatgg gtgctctatt agatactgca atagctttag cattaggagg
    22681 aactactgca ggccttgcaa atctaattaa agtaaaagga aaacatgcag caaaaagtgc
    22741 tattcgttca gcaatttcta gatatctagg tagttggttt gtaaatgatg ttgctttaga
    22801 attcgctatg aatttattat caccggggat ttatttagca caattatggg ataaaaatga
    22861 tgccattcct aacaacggaa ggattaactt ttaatcatga gatatacaat aaaattaatt
    22921 gggtataacg tattttcgtt gtttatattc tttatcttat caatgttgtt taaagttccc
    22981 tttaggtggt ggatcagcat tgcaatgacg acttcgtcgt acattgtata taattactta
    23041 aagaaaaaga gagaaaagga atgatcttat accagatcat tccttttctg ctttctgtaa
    23101 atccctcgga gtgtgtttgg cgctttgata cgaagtgtca aagctgtata aacgttacta
    23161 tttccaaaaa agtaacagaa aattcctgct ttgtaggact gctttgggtg agtaatagac
    23221 atgtagactc accctatctc ctgatggcga aaagaattta gcaatgatgc aagttgttct
    23281 gaactcgaga aaaaacatgc cgaaatcgaa gaaaagcgtg cagaacttga agcgaagaag
    23341 caagaaatgt tgaagctctt ggataaatag aatttagaaa acagaaaaaa ctaaaaaaaa
    23401 tgtagggttt atttccctac attcttaaaa taacttagta cataaatgac aatgctgcca
    23461 ctgccgtcaa tattgcaaaa actattttcc aaattttttt attttttcca aaaatcttat
    23521 caggtaacaa gcttattaca agaaaggtaa taaacaacac caatttaagt gtgtatatca
    23581 taaaaacacc ttctttccta caattatatt ataatacttt atgtaagcga atataataga
    23641 tgtgaggtaa ccaactacga aaaaatataa ggctgaagac agtaaaaacc agcatttaaa
    23701 gccttcactg tatctaggat ttccctattt ttagacaaga ttgacccaaa tccacagcat
    23761 ttaaaaaagc gaatttcaat tgaaactcgc ttttttacaa gatgtattag tataaatttg
    23821 tatcttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa
    23881 gcaccgcttt gaggttgcag ataaagctga cgtggtttga agagattttc gaagagtatt
    23941 agttcaagtg ccagatgtct tcgttatact gagcgattgt acggtcagat gagaagaatc
    24001 ctgctttaga aatgttaacg atgactttat ccaaccatgc gtcacggtct tcgtagtcag
    24061 caagcatttg ctctttgact ttgatgtagt cttccaaatc aagaagagtc atgaaccagt
    24121 ctttgttgat caattcattg taaagacgtt ccaagcgctc tttgtttcca gctgcaagaa
    24181 ctgcatcact aacgatgaag tcaaccaatg gtttgatagc ttcacgagcg tagaattcgc
    24241 ttgatttgta agctgctttt gcgtaaaggt cgataacagt ttctgaattt tcaccgaaga
    24301 tgtagatgtt ttcttctcca accaactcag cgatttccac gttagcaccg tccatagtac
    24361 caagtgtcaa agctccgttc aacatgaatt tcatgttacc agtacctgaa gcttctttag
    24421 aagcaagtga gatttgttct gagatatcac atgctgggat aaggaaactt gctgcagtaa
    24481 cgttgtagtt ttcaaccata actacttgca agtgtggagc tactgctgga tcgttagcaa
    24541 taacttctga catgcaaagg attaaatgga taatgtcttg agcgattgtg taggctggag
    24601 ctgctttacc accaaagaag attgtgattg gacgagcagg gatgttacca gctttgatgt
    24661 caaggtattt gtggatcacg tacaaagcgt tcatttgttg gcgtttgtac tcgtgaagac
    24721 gtttgatttg gatatcaaag atagaatttg gattgatttc cacaccttgg tgttctttca
    24781 agtgacgagc caatttacgt ttgttgtgag ccttgatgct ttccaatttt tctttgacag
    24841 ctgctttgtc ttcataagac aacagttttt caagctcatc tgcttcatgg tgccaaccat
    24901 ctccaagaat ctcatccaag tagtgagaca atcttgggtt agcatgcata agccaacgac
    24961 ggaaagtgat accgtttgtt ttgttgttga acttttctgg gtaaaggtcg tagaaggctt
    25021 tcaactcaga atttttcaag atttcagtat ggagtgctgc aaccccgtta acactgtatc
    25081 cgtagtggat atccatgtga gccatgtgaa cacgtccgct ctcatcgatg atttgaacag
    25141 ctggatcttt gtactctgcc ttcacacgac ggtccaattc ttcgatgatt ggtaccaagt
    25201 gaggaaccac ttcttgcaag aattcaagag gccatttttc aagcgcttca gcaaggattg
    25261 tgtggttagt gtaggcagtc atgctacgaa caattgagat tgcttcgtca agatcgatac
    25321 cacgtgcagt caaaagacga atcaattcag gaatcaccat tgatgggtga gtatcgttga
    25381 tttggacaac tgcgtagtca gcaaggtcat gcaagttgct tcctttttcg attgcttcgt
    25441 cgatgatcaa ttgcgcaccg tttgaaacca tgaagtattg ttggaagata cggagcaatt
    25501 caccttgacg gtcactatca tctgggtaaa ggaagagagt taagttgcga gcgatatctg
    25561 tcttgtcaaa gttgatacca tctttaataa tagaagaatc aactgaatcc aagtcaaaca
    25621 aacgcaagcg gtttttagtc gctgtttcat aaccagtaac atcaatatcg taaagagttg
    25681 atgtcaaagt aaagtctgca aatggtactt ggtagctacg gcttgagcga accaaccagt
    25741 tttgctctgt caaccatgca tttggaattg tttcttgttg gttgttttta agaacttgtt
    25801 ggaaaagacc aaagtggtag ttaagaccaa caccgtcacc attcaaacca agagtagcaa
    25861 ttgagtcgat aaagcaggca gccaaacgtc ccaaaccacc attaccaaga gatggttcca
    25921 attcaacttc ttcaacttcg atcaagtctt tacctgcagc tgcaagttct tttttaacat
    25981 cgtcgtaaag accaaggtta atcaagttgt ttgacaagag tttaccaatc aagaactcag
    26041 ctgagatgta gtaaactttt ttcttaccag tgttgactgg tttttggctg cttgcaagct
    26101 tgctgtagtt aagaagagca aggtaaagct cttcattgct acattctgca atggttttat
    26161 tgtaacgatt ttgtacaaat tcttgtagtg ataacatgtt tagttgtctc ctgattattg
    26221 tcttatttct ttaaatctac caaattttca ttaattcggc gataaattgt tgtcaagtca
    26281 agcaaacctt cctcgacagc tggtgtcaat tgatcttcag tcatacgcca agaccagttt
    26341 ccaccaaggg tagatgggaa gttcatacga gctgcctcat ccaattctag taaatcttgc
    26401 atagttgcaa ttgccataaa gctaactgat gaaaatactg tacgaagcat agcgtgtacc
    26461 actgtttcgt attctttacg gttcgtgtaa cgagccatgt actcacgagt cgcatcatca
    26521 atctcattac ggtaccaacc aagaaccgta ttgttatcgt gtgttcctgt gtacataact
    26581 gagttagcag gtgccaagtg tgggctatca atgctttcgt cttctgggtt gaaggcaaat
    26641 tgaagaatct tcattcctgg gaagccagta cgttcacgca attcgatcac ttcatctgtc
    26701 atgaagccaa ggtcttctgc gatgatgttt agctcaccaa gttcttcctt aacggctgca
    26761 aaaagcttgt agcctggacc tttcacccac tcaccaggtg ctgctgtatc ggaaccagca
    26821 gggatttccc agtaagattc gaagccacgg aagtggtcga tacgaacgat atcgtagatt
    26881 ttgaagcttt cacgcaagcg ttcaatccac catttgtagc cgtctttgtc cattgcttcc
    26941 cagtcataga ttgggttacc ccaaagctga ccagttacag aaaactcatc tggtgggcat
    27001 cctgcgatac aagtagcctt accattgaca tctgttttga agagatgtgg atttgcccac
    27061 atatcacttg aatcttccgc tacgtagatt ggcatgtccc caacgatttc gatgtggttg
    27121 tcgttagcgt aagctttcaa tttcaaccat tgttggaaga agaagtattg agtcacacgg
    27181 tggtaaacca acttgtctgc caattgctca cgatagcttt caagtgctga agctttacga
    27241 gcacgagcat ctgcatctgg ccattcagtc caagcaagat tgtcaaaata ctctttgata
    27301 gccatatact cagcaaagag ctcaagccat gattggttgt cttgagcaaa tttctcaaaa
    27361 tctttaacat ctccgacttc aaagaaacgt ttcaccgctt tttctaaaag aggacgacgt
    27421 gcatagtaga ttttagcata gtcaacttca gacgcatcgc taccaaagtc aactccttca
    27481 aggtcacttg cttccaacaa accttgctcc accaagatat ctaaatcgat aaaatgagtg
    27541 tttcctgcga aggctgagaa agattggtaa ggagaatccc cgtaactagt tgctcctaat
    27601 ggaaggattt gccagtaacg ttgttttgta cggaccaaga aatcaacgaa gtcgtaagca
    27661 ctttgaccaa atgatccgat tccgtaagct cctggaagag aagagatgtg catcaacaca
    27721 ccactttgac gttttttcat aatagcacct cgtgtgttaa aataatggaa cgttgcgtat
    27781 tttgcagacg caaacgtttg cgttacttat aagtatactc cttttcaagc ataattgcaa
    27841 gcgtttttaa aaaacttttt tgattatttt taaggagact aactcatttt agcaaagata
    27901 acttaaaact atctaatcct aaggtttgac tctcacgaga cagtctacaa agtacaaaac
    27961 ctccttaggg agcttgaatt tatatgtaac aaagcacaaa cgtccataga aaatagatag
    28021 ggattagaac cagggaggta gcccctcctg gtttccctct ttagacagat tccatatatt
    28081 tttattaaaa atactgtatt cttatctatt tcatactttt cttctattaa aatgcaaaat
    28141 tatgctatca aatcaagctt aaaaattttt taaaattttt acaaaaaata cttgcaaccg
    28201 ttttctattt gtgctatact aagctcataa aggaaaacgt ttgcgtttcc ttatcaataa
    28261 aacttgctat tctttgggag gaatacacta tgtcatctaa atttatgaag agcactgcgg
    28321 tgcttggaac tgttacactt gctagcttgc ttttggtagc ttgcggaagc aaaactgctg
    28381 ataagcctgc tgattctggt tcatctgaag tcaaagaact cactgtatat gtagacgagg
    28441 gatataagag ctatattgaa gaggttgcta aagcttatga aaaagaagct ggagtaaaag
    28501 tcactcttaa aactggtgat gctctaggag gtcttgataa actttctctt gacaaccaat
    28561 ctggtaatgt ccctgatgtt atgatggctc catacgaccg tgtaggtagc cttggttctg
    28621 acggacaact ttcagaagtg aaattgagcg atggtgctaa aacagacgac acaactaaat
    28681 ctcttgtaac agctgctaat ggtaaagttt acggtgctcc tgccgttatc gagtcacttg
    28741 ttatgtacta caacaaagac ttggtgaaag atgctccaaa aacatttgct gacttggaaa
    28801 accttgctaa agatagcaaa tacgcattcg ctggtgaaga tggtaaaact actgccttcc
    28861 tagctgactg gacaaacttc tactatacat atggacttct tgccggtaac ggtgcttacg
    28921 tctttggcca aaacggtaaa gacgctaaag acatcggtct tgcaaacgac ggttctatcg
    28981 caggtatcaa ctacgctaaa tcttggtacg aaaaatggcc taaaggtatg caagatacag
    29041 aaggtgctgg aaacttaatc caaactcaat tccaagaagg taaaacagct gctatcatcg
    29101 acggaccttg gaaagctcaa gcctttaaag atgctaaagt aaactacgga gttgcaacta
    29161 tcccaactct tccaaatgga aaagaatatg ctgcattcgg tggtggtaaa gcttgggtca
    29221 ttcctcaagc cgttaagaac cttgaagctt ctcaaaaatt tgtagacttc cttgttgcaa
    29281 ctgaacaaca aaaagtatta tatgataaga ctaacgaaat cccagctaat actgaggctc
    29341 gttcatacgc tgaaggtaaa aacgatgagt tgacaacagc tgttatcaaa cagttcaaga
    29401 acactcaacc actgccaaac atctctcaaa tgtctgcagt ttgggatcca gcgaaaaata
    29461 tgctctttga tgctgtaagt ggtcaaaaag atgctaaaac agctgctaac gatgctgtaa
    29521 cattgatcaa agaaacaatc aaacaaaaat ttggtgaata aaaaatttgt tcaagggggg
    29581 tggaaatcaa atcccccttt gaatttatca atagagacac aaataattta gctttcttat
    29641 aaaaaagtag tatcctatga aaggagttaa tatggaaaag caacaaccta gtaaagcagc
    29701 cctgctgtct atcattcctg ggttaggaca gatttacaat aaacaaaaag ccaaaggttt
    29761 tatcttcctt ggtgtaacca tcgtatttgt cctttacttc ctagcacttg caacccctga
    29821 attgagcaac ctcatcactc ttggtgacaa accaggtcgt gataattccc tctttatgct
    29881 gattcgtggt gccttccatc taatctttgt aatcgtttat gtactctttt atttctcaaa
    29941 tatcaaagat gcacatacga ttgcaaaacg cattaacaat ggaattccag ttccacgcac
    30001 actcaaagac atgatcaaag ggatttatga aaatggcttc ccttacctct tgatcattcc
    30061 atcttatgtt gccatgacct tcgcgattat cttcccagtt atcgtaacct tgatgatcgc
    30121 ctttaccaac tacgacttcc aacacttgcc accaaacaag ttgttggact gggttggttt
    30181 gaccaacttt acaaacattt ggagcttgag taccttccgt tctgcctttg gttctgttct
    30241 ttcttggact atcatttggg ctttggcagc ttctacttta caaatcgtaa ttggtatctt
    30301 cacagctatc attgccaacc aaccatttat caaaggaaaa cgtatctttg gtgttatttt
    30361 ccttcttcct tgggctgtcc cagccttcat cactatcttg acattctcaa acatgtttaa
    30421 cgatagtgtc ggtgctatca acactcaagt attgccaatc ttggctaaat tccttccttt
    30481 ccttgatgga gctcttattc cttggaaaac agacccaact tggactaaga ttgccttgat
    30541 tatgatgcaa ggttggctcg gattcccata catctacgtt ctgaccttgg gtatcttgca
    30601 atctattcct aacgaccttt acgaagcagc ttatattgac ggtgccaacg cttggcaaaa
    30661 attccgcaac atcactttcc caatgatttt ggctgttgcg gcacctactt tgattagcca
    30721 atacaccttc aactttaaca acttctctat catgtacctc ttcaatggtg gaggacctgg
    30781 tagtgtcgga ggtggagctg gttcaaccga tatcttgatc tcatggatct accgtttgac
    30841 aacaggtaca tctcctcaat actcaatggc ggcagctgtt accttgatta tctctatcat
    30901 tgtcatctca atctctatga tcgcattcaa gaaactacac gcatttgata tggaggacgt
    30961 ctaagatgaa taactcaatt aaactcaaac gtagactgac tcaaagcctt acttaccttt
    31021 acctgattgg tctatcaatt gtaattatct atccactgtt gattaccatt atgtcagcct
    31081 ttaaagcagg taacgtctca gcctttaaac tagatactaa tatcgacctc aattttgata
    31141 actttaaagg cctcttcact gaaaccttgt acggtacttg gtacctcaac actttgatta
    31201 tcgccttaat taccatggct gttcaaacaa gtatcatcgt acttgctggt tatgcttaca
    31261 gccgttacaa cttcttggct cgtaaacaaa gtttggtctt cttcttaatc atccaaatgg
    31321 tgccaactat ggccgctttg acagccttct tcgttatggc gcttatgttg aacgccctta
    31381 accacaactg gttcctcatc ttcctctacg ttggtggtgg tatcccgatg aatgcttggc
    31441 tcatgaaagg ctacttcgat acagtgccaa tgtctttaga cgaatctgca aaactagacg
    31501 gtgcaggaca cttccgccgc ttctggcaaa ttgttctacc acttgttcgc ccaatggttg
    31561 ccgtacaagc tctctgggcc ttcatgggac ctttcgggga ctacatcctc tctagtttct
    31621 tgcttcgtga gaaagaatac tttactgttg ccgtaggtct ccaaaccttc gttaacaatg
    31681 cgaaaaactt gaagattgcc tacttctcag caggtgctat cctcatcgcc cttccaatct
    31741 gtattctctt cttcttccta caaaagaact ttgtttcagg acttacaagt ggtggcgaca
    31801 agggataatt tatccccgcc accctttttc attttatact cttcgaaaat ctcttcaaac
    31861 cacgtcagct ttatctccaa cctcaaagtt gtgctttgag caacctgtgg ctagtttgca
    31921 ctttgatttt cattgattat tagcaattgt cactgtaaat aatatccttg tagcaagcaa
    31981 tttttctcct agacttgaaa taaagcgcat ttctctatat aataatactc atatagaaaa
    32041 caccttttag aaagatacct atgcttccat atccattttc ctatttttca agtatttggg
    32101 ggtttcgtaa gcccctgtcc aaacgtttcg agctcaactg gtttcaactt ctctttacca
    32161 gtatcttcct tatcagcttg tctatggtac ccattgctat ccaaaacagc tcccaggaga
    32221 cctatccgct agaaactttt atcgataatg tctatgaacc tctgacagat aaggttgtcc
    32281 aggatctctc tgaacatgct acaattgtcg atggcacatt aacttatact ggaacagcta
    32341 gtcaagcccc ttctgttgtg attggtccaa gtcaaatcaa ggaattacct aaggacttgc
    32401 aactgcattt cgatacaaat gaactagtca tcagcaagga aagcaaggaa ctgacccgca
    32461 tctcttaccg agccattcag actgagagtt tcaaaagcaa agacagcttg acccaagcaa
    32521 tttctaaaga ctggtaccaa caaaatcgtg tctatatcag cctcttccta gttctcggtg
    32581 cgagcttcct ctttggtttg aatttcttta tcgtctctct aggagctagt cttctccttt
    32641 atatcactaa gaaatcacgc ctcttttcat ttagaacctt taaagagtgc tatcacttta
    32701 tcttgaactg tttaggattg ccgactctga ttacacttat tttgggatta tttggccaaa
    32761 atatgacaac cctgattact gtacaaaata ttctttttgt tctgtatctg gtcactatct
    32821 tttataaaac acatttccgt gatccaaatt accataaata ggagattttt atgcccgtta
    32881 cgattaaaga cgtggccaag gctgctggtg tttcgccttc aaccgtaacc cgtgttattc
    32941 aaaataaatc aaccattagc gacgaaacaa aaaaacgcgt tcgcaaagct atgaaggaac
    33001 tcaactacca cccaaacctc aacgctcgta gcttggtaag cagctatact caggttatcg
    33061 gattagttct tcctgatgac tcagacgcct tctaccagaa tcctttcttt ccatcggttc
    33121 tacgtggcat ctctcaagtc gcatctgaaa accactatgc cattcagata gcaacaggga
    33181 aagatgagaa ggagcgtctc aacgctattt cacaaatggt ctacggcaag cgtgtagatg
    33241 ggctaatctt tctctatgcc caagaagaag accctctcgt aaaactcgtc gcagaagaac
    33301 agttcccctt ccttatccta ggtaaatctc tatctccttt catcccactt gtcgacaacg
    33361 acaatgttca agctggtttt gatgcgactg aatatttcat caaaaaaggc tgcaaacgca
    33421 ttgcctttat cggaggaagt aaaaagctct tcgtgaccaa agaccgttta acaggctatg
    33481 aacaggcgct taaacattac aaacttacca ctgacaacaa tcgcatctac tttgccgacg
    33541 agtttctgga agaaaagggc tataaattta gcaagcgatt attcaagcac gatccacaaa
    33601 ttgatgctat catcacaacc gatagcctcc tagctgaagg tgtttgtaac tatattgcca
    33661 aacaccagct ggatgtccct gttctcagct ttgactcggt taatcccaag ctcaacttgg
    33721 cagcctatgt cgatatcaat agtttagagc ttggtcgtgt ttcccttgaa actattctcc
    33781 agattattaa tgataataaa aacaataaac aaatttgtta ccgtcaattg atcgcccaca
    33841 aaattatcga aaaataagag actgggcaaa aagtcgttaa aagcaaaaac gcatactatc
    33901 aggtattgaa aaaacttgat actatgcgtt ttattgtggg aagatttact tccttttctt
    33961 ctgaaattga gttgttaccc aagatctttt tatactcaat aaaaatcaaa gtgcaaacta
    34021 ggaagctagc cgcaggttgc tcaaaacact gttttgaggt tgtggataga actgacgaag
    34081 tcagctcaaa acatggtttt gaggttgcag atagaactga cgaagtcagt aacataccta
    34141 cggcaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtattaat cactaattat
    34201 ctatctcaac aaatcttcct agaatatgaa cattttccga gacagagaca aaggagcttg
    34261 gatccacttg tgtcataatc tgtttaaatt cattaaactc tgcacgtgta atgacagtga
    34321 ttaaaactgc ctttctctcg tgattatagg ttccttctgc atcgtggatc atggttgctc
    34381 cgcggtgcaa ttttttatgg attttttcaa ttaccttctc tggatgattt gtcacaatca
    34441 tggcctgcat acgcttttgc ttagtaaaga ctgcgtctgt cacacggcta gagacaaaga
    34501 tggtaatcat agaataaaga gcgtatttcc aaccaaaggt caaacctgct atcagcatga
    34561 tagttccatt taccaagaaa gaaatactac cgacattctt acccgttttc ttgcgaatag
    34621 tcaggctgac gatatccgtc ccaccactgg agatattgtt tcgaagagca aaaccaatcc
    34681 ccaaacccat aacaacaccc ccaaaaaggg aattgataat gggatcctcc gtcaaggttg
    34741 ccacagggac aaactggata aagaaggaac tcatagatac cgtgataaag gtaaagacgg
    34801 tgaacttatg gccaatctga taccaagcta agaccatcaa agggaagtta atggcgtaga
    34861 agcttagcga aatcggaata tgaaaaccaa accagtgatt actcaaggca gagataatct
    34921 gtgccagacc tgttgcacca ctcgaataca catgccctgg ttggaaaaag aaattaactg
    34981 ctactgctga taaaaaacca tagaccagag aggccgaaat cttctcatca tacttttctc
    35041 gagagatact ttgtaagaca cgtaaaattt ttatctgata agcaaagcgg cgcagataat
    35101 agcgccaccg cttaattcgt tttgtttgtt tcatcttctt ctacttgtaa gctgagttcc
    35161 tctagttgtt tgagagcgac tgttgatgga gcttgtgtca ttggatcagt tgccttgttg
    35221 ttcttaggaa aggcaatgac ttcacggata ttttcttctc cagcaagcaa catgacaaaa
    35281 cggtcaagcc cgatagccaa accaccgtgt ggtgggaaac catagtccat ggcttcaaga
    35341 aggaaaccaa actggtcatt ggcttcttca gctgagaaac caagagcctt gaacatgcgt
    35401 tcttgaaggt ctttttggtt gatacgaagg ctaccaccac caagctcata accgttcaag
    35461 acgatatcgt aagcaatggc acgaacctta gccaaatcac cttctaattc gtgagcagtc
    35521 tcttcctgtg gaagtgtgaa tggatggtgg gcgctcatgt agcggccttc ttcttcagac
    35581 cattcaaaca tcggccagtc aaccacccaa aggaagttga acttatcatt atcaatcaag
    35641 ccaagctctt tagcaatacg tccacgaagg gcacccagtg ttgcattagc cacttcaagc
    35701 gtatccgcca caaagagaac caagtcctta tcttcaagag caagcgctgt tgtcaattct
    35761 tcttggatac cagtcaagaa cttggcaact ggtccgttta attctccatc aaccaccttg
    35821 acccaagcaa gacctttggc accatactgt ttggctactt ccgtcatctt gtcgatgtct
    35881 ttacgtgaat agttgtccgc agctcctttg accacaatcg cttttacagc aagtgcttct
    35941 gaaaagactt taaagtctac acctttgacc acttctgtca agtcctgaag caacatgtca
    36001 aaacgagtat ctggcttgtc agaaccgtaa agagccatag catcatcgta tttcatacga
    36061 gggaacggta gcgttacttc gatgcctttt gtttccttca tcacacgcgc gatcaagcct
    36121 tctgtaatat cttggatttc ttgctcagta aggaaggacg tttccaagtc gacctgagta
    36181 aattcaggct ggcggtctcc acgcaagtcc tcgtcacgga aacatttaac gatttggtag
    36241 taacggtcaa aaccagcatt catcaagagc tgtttcgtga tttgtggact ttgaggaaga
    36301 gcgtaaaaat gccccttatt aacacgagac ggcactaaat aatcacgcgc cccttcaggc
    36361 gttgacttag aaaggaatgg tgtctccacg tcgataaact ccaactcatc caagtagttg
    36421 cggatagagt gggtcacctt ggcacgaagt ttaagatttt ccaacatttc tggacgacga
    36481 aggtcaaggt aacggtaacg caaacgtgta tcgtcatttg cctcaatgcc atccttaatc
    36541 tcaaatggtg ttgtcttagc tgtgttaagc acaataagag ctgtcacgtt taactcaacc
    36601 gcaccagttg gcaacttatc attggcttgc tcacgcgcag cgacctgacc agtcacctca
    36661 ataacaaatt cgctacgaag gctttcagct gttgccataa cctctgcaga tactttttca
    36721 gggttgataa ccaactgcat gattccttca cggtcacgaa gatcgataaa gatcaaacca
    36781 ccaaggtcac gacgacggcc aacccatcct ttcaaggtta tttcttgtcc gatgtgttcc
    36841 tcacgaacac gaccagcata catactacgt ttcattattt ctctcctctt ttattctgtt
    36901 actattttac cataaaagcg caggctcttc atgaaaatca tcagaaaagt ttgccagtct
    36961 ttaaaagtca ggtgaaagcc ctaaaaatta gcgctaatgc tcttcgaaaa tctcttcaaa
    37021 ccacgtcagc gtcgcctt
//
LOCUS       DBERDS010000018        34619 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.018, whole genome shotgun sequence.
ACCESSION   DBERDS010000018 DBERDS010000000
VERSION     DBERDS010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.018"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            215..2107
                     /gene="pepO"
                     /locus_tag="ACL73E_001012"
     CDS             215..2107
                     /gene="pepO"
                     /locus_tag="ACL73E_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGS0800998.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2229..2858)
                     /locus_tag="ACL73E_001013"
     CDS             complement(2229..2858)
                     /locus_tag="ACL73E_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS0800999.1"
                     /translation="MKIYKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            3852..6074
                     /locus_tag="ACL73E_001014"
     CDS             3852..6074
                     /locus_tag="ACL73E_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015968 - stringent response [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HGS0801000.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            6104..6547
                     /gene="dtd"
                     /locus_tag="ACL73E_001015"
     CDS             6104..6547
                     /gene="dtd"
                     /locus_tag="ACL73E_001015"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGS0801001.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6814..6999)
                     /locus_tag="ACL73E_001016"
     CDS             complement(6814..6999)
                     /locus_tag="ACL73E_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801002.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(7018..7431)
                     /locus_tag="ACL73E_001017"
     CDS             complement(7018..7431)
                     /locus_tag="ACL73E_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801003.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(7562..8269)
                     /locus_tag="ACL73E_001018"
     CDS             complement(7562..8269)
                     /locus_tag="ACL73E_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter family
                     protein"
                     /protein_id="HGS0801004.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGL
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQISQKQVKLAVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(8388..9038)
                     /locus_tag="ACL73E_001019"
     CDS             complement(8388..9038)
                     /locus_tag="ACL73E_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGS0801005.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMVIAKQLYVEKIN"
     gene            9150..9992
                     /locus_tag="ACL73E_001020"
     CDS             9150..9992
                     /locus_tag="ACL73E_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0801006.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQLHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            10068..10505
                     /locus_tag="ACL73E_001021"
     CDS             10068..10505
                     /locus_tag="ACL73E_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGS0801007.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10574..10876
                     /locus_tag="ACL73E_001022"
     CDS             10574..10876
                     /locus_tag="ACL73E_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801008.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSFISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(10967..12040)
                     /locus_tag="ACL73E_001023"
     CDS             complement(10967..12040)
                     /locus_tag="ACL73E_001023"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGS0801009.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPSQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPK
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            12196..12873
                     /locus_tag="ACL73E_001024"
     CDS             12196..12873
                     /locus_tag="ACL73E_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0801010.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12866..13840
                     /locus_tag="ACL73E_001025"
     CDS             12866..13840
                     /locus_tag="ACL73E_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGS0801011.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13889..15832)
                     /gene="thrS"
                     /locus_tag="ACL73E_001026"
     CDS             complement(13889..15832)
                     /gene="thrS"
                     /locus_tag="ACL73E_001026"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGS0801012.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15890..16213)
                     /locus_tag="ACL73E_001027"
                     /pseudo
     CDS             complement(15890..16213)
                     /locus_tag="ACL73E_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(16470..16833)
                     /locus_tag="ACL73E_001028"
                     /pseudo
     CDS             complement(16470..16833)
                     /locus_tag="ACL73E_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17070..17699
                     /locus_tag="ACL73E_001029"
     CDS             17070..17699
                     /locus_tag="ACL73E_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS0801013.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTPDFPEEFKPLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            17840..18109
                     /gene="rpsO"
                     /locus_tag="ACL73E_001030"
     CDS             17840..18109
                     /gene="rpsO"
                     /locus_tag="ACL73E_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGS0801014.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18924..19538
                     /locus_tag="ACL73E_001031"
     CDS             18924..19538
                     /locus_tag="ACL73E_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGS0801015.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19831..20580)
                     /locus_tag="ACL73E_001032"
     CDS             complement(19831..20580)
                     /locus_tag="ACL73E_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGS0801016.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20713..23049
                     /locus_tag="ACL73E_001033"
     CDS             20713..23049
                     /locus_tag="ACL73E_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGS0801017.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            23151..23828
                     /locus_tag="ACL73E_001034"
     CDS             23151..23828
                     /locus_tag="ACL73E_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGS0801018.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            23815..24612
                     /locus_tag="ACL73E_001035"
     CDS             23815..24612
                     /locus_tag="ACL73E_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGS0801019.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24629..25732
                     /locus_tag="ACL73E_001036"
     CDS             24629..25732
                     /locus_tag="ACL73E_001036"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGS0801020.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25988..27007
                     /gene="galE"
                     /locus_tag="ACL73E_001037"
     CDS             25988..27007
                     /gene="galE"
                     /locus_tag="ACL73E_001037"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS0801021.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKVMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            27009..27974
                     /locus_tag="ACL73E_001038"
     CDS             27009..27974
                     /locus_tag="ACL73E_001038"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0801022.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAAHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(28025..28231)
                     /locus_tag="ACL73E_001039"
     CDS             complement(28025..28231)
                     /locus_tag="ACL73E_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGS0801023.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            28283..28759
                     /locus_tag="ACL73E_001040"
     CDS             28283..28759
                     /locus_tag="ACL73E_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGS0801024.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISFSSSSQPEQSSELESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            28768..29439
                     /gene="cmk"
                     /locus_tag="ACL73E_001041"
     CDS             28768..29439
                     /gene="cmk"
                     /locus_tag="ACL73E_001041"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGS0801025.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            29570..29908
                     /locus_tag="ACL73E_001042"
     CDS             29570..29908
                     /locus_tag="ACL73E_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGS0801026.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            29911..30540
                     /locus_tag="ACL73E_001043"
     CDS             29911..30540
                     /locus_tag="ACL73E_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGS0801027.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            30780..31931
                     /locus_tag="ACL73E_001044"
     CDS             30780..31931
                     /locus_tag="ACL73E_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0801028.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32244..32993
                     /gene="truA"
                     /locus_tag="ACL73E_001045"
     CDS             32244..32993
                     /gene="truA"
                     /locus_tag="ACL73E_001045"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGS0801029.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFILDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRKLAGPTAAPNGLYLKEIRYEE"
     gene            32983..33756
                     /locus_tag="ACL73E_001046"
     CDS             32983..33756
                     /locus_tag="ACL73E_001046"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS0801030.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            33734..34195
                     /locus_tag="ACL73E_001047"
     CDS             33734..34195
                     /locus_tag="ACL73E_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0801031.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            34420..34619
                     /locus_tag="ACL73E_001048"
                     /pseudo
     CDS             34420..34619
                     /locus_tag="ACL73E_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        10021 a         6484 c         7907 g        10207 t
ORIGIN      
        1 taataactga aaaatagatt ctaaagataa ctttcaggat aaatttctaa attataaaac
       61 gcatagtatc aagtgtaaaa aacttggaat tatgcgtttt atcatggaaa gattttttat
      121 aatagctaaa aaataatagt taaatggtta ttaattgcat tccctagtga tttttgttaa
      181 gataaatgca aatacaaatg aaagcgagaa caagatgaca cgttatcaag atgattttta
      241 tgatgctatc aatggagaat ggcaacagac agctgaaatc ccagcagata agtctcaaac
      301 tggaggtttt gttgatttag accaggaaat tgaagacctg atgctggcga caacagacaa
      361 gtggttagca ggtgaagagg tgcctgagga tgctatcttg gaaaactttg tcaaatacca
      421 ccgcctagtt cgtgattttg acaagagaga agctgacggt atcacacctg tcttaccact
      481 ccttaaagaa ttccaagaat tggaaacttt tgcggatttt acagctaaac tagcagagtt
      541 tgagcttgca ggaaaaccaa acttccttcc ttttggtgta tcgccagact ttatggatgc
      601 tagaatcaat gttctatggg ctagcgctcc aagcacaatc ttgccagata cgacctacta
      661 tgcagaagaa catcctcagc gcgaagaact cttgactctt tggaaagaaa gcagcgcaaa
      721 tctcctcaag gcttatgatt tctctgatga agaaattgaa gacttgctag aaaaaagact
      781 tgaattggac cgccgagttg cggcagtggt gctctctaat gaagaaagtt cagaatatgc
      841 taaactctat catccatatt cttacgaaga tttcaagaaa ttcgcgcctg ccctaccttt
      901 ggatgacttc ttcaaagcag ttattgggca attaccagac aaggttattg tagacgagga
      961 acgtttctgg caagcagcag agcaattcta cagtgaggaa gcctggtctc tccttaaagc
     1021 aaccttgatt ttgagtgttg tcaatctttc aaccagctat ttaacagagg atatccgtgt
     1081 tttgtctggt gcctacagcc gtgccctttc tggagttcca gaggcaaaag ataaggtcaa
     1141 agcagcttat catctagcac aagaaccttt caagcaagcc ctgggtcttt ggtacgcccg
     1201 tgagaagttc tctccagaag ccaaggcgga tgtggagaaa aaagtggcaa ccatgattga
     1261 tgtttataag gagcgtctgc ttaagaatga ctggctcact ccagaaacct gtaaacaggc
     1321 tatcgtgaag ctcaatgtga tcaaacctta tattggctat ccagaagaat tgcctgcacg
     1381 ttacaaggat aaggtagtga atgaaactgc cagtcttttt gagaatgctc tagcctttgc
     1441 gcgtgtggaa atcaagcaca gttggagtaa gtggaaccag cctgtagatt ataaggaatg
     1501 gggcatgcct gctcatatgg tcaatgccta ctacaatcct cagaagaacc tgattgtctt
     1561 tccagcggcc attttacagg cgcctttcta tgacttgcat cagtcatctt ctgctaacta
     1621 cggtggtatt ggggcagtga ttgcccatga aatttcccac gcctttgata ctaacggggc
     1681 ttcctttgac gaaaatggta gcctcaagga ttggtggaca gagagcgact atgctgcctt
     1741 caaggagaaa acacaaaaag tcattgacca atttgatgga caggattctt atggagcaac
     1801 cattaacggt aaattgactg tatcagaaaa cgtggctgac ttgggaggaa tcgcagcagc
     1861 gcttgaagca gctaagagag aagcagactt ctcagcagaa gagttcttct acaacttcgg
     1921 tcgcatctgg cgcatgaaag gtcgaccaga atttatgaaa cttttggcta gcgtcgatgt
     1981 gcacgcacca gccaaactcc gtgtcaatgt gcaagtacca aacttcgacg atttctttac
     2041 aacctatgat gtcaaagaag gagacggaat gtggcgttca ccagaggagc gcgtgattat
     2101 ttggtaatac aaaaaatcta gtcatcagaa aaaggcatcc aatcacgtgt gaaaaccttg
     2161 ataggatgcc ttttgtaata gaaagatttg ctggatagtt tacttaaatt tcgattgtca
     2221 tcatcttgct aaaaaaaggg attgaaggcc ttttcgtgag cgatagtagt agctggacca
     2281 tgtcctggat agacatcgta gtttggtagg gtgaagagtt gggtctggat actatgaagg
     2341 agttgctcca tgctaccagt cggaaggtcg gtccgtccga tagtttcgcg gaatagagca
     2401 tctcccgtca agactaggtg agcatcagga aagactaggg aaacaccacc gatagagtgc
     2461 cctggggtcg gtagaacctt aaaacgaaat tcctctagtt ggtattcttc gtgaaagaca
     2521 aaggtgtgtt ctgcaggttt tgtgaccaca tctgccatat catcgtggcg agggagaccg
     2581 gagagattat cgacaggagt gtagagccag ctggcttcgc tctctgcgat atagacagga
     2641 ggattgccaa acgtctcgcg aaccaagtcc agactcatga tatggtcata atgggcgtgg
     2701 gtcaagagaa tagcacagat cggtttgttg atcttctcga ttgtctgacg aatggcttcc
     2761 caatgactac caggatcgac gacgatgagg tgcttttcgc cttctagata ataggtattt
     2821 tcataggcaa caggattcac ggttttatag attttcatac tagctccaat ctcaaagaat
     2881 atactaatac tcttcgaaaa tctcttcaaa ccgcgtcaac tttatctgca acctcaaagc
     2941 agtgctttga acagcctgcg gctagctttc tagtttgctc tttgattttc attgagtata
     3001 aattaagtat agcacagtta gggagaatag gtaaggattt aaaatgaact taaaaaccag
     3061 catgactaga tgaagacagg ctggttatca atttatcaat attggaaagg tgtcaattgc
     3121 ccttcatagg ttgcataaac tccgtcatta gcttgtttga tagacgtgat gtttagagtg
     3181 ctaccgtagt tggcttctca tttgtcgcta tattcactat aagttatcct actgggcagg
     3241 ttctggtcgt tagcatagta ttgaacgagt tttttatagc tttgctggct gaataggaac
     3301 aggcagcaaa ctcctaacat taggagagca aagatagaaa tagcagtttt tttcataggt
     3361 attctcctta taaactaaag gatagaagaa agtatcttga ggatttttat actcttcaaa
     3421 aatctcttca aaccgcgtca acgtcgcctt gccgtatata tgtgactgac tttgtcagtc
     3481 ttatctacaa cctcaaagca gtgctttgag caacctgcgg ctagtttcct agtttgctct
     3541 ttgattttca ttgagtatta attccaaaat ccagtcaagg taccagtgta tgtgatacga
     3601 gttccaccgt ttatctttcg tatcttcaat ggaattgggg aaatcagaaa gtctttgggt
     3661 tacaatatgg tttccgttct tctatctctc cttctatcac ctaagtttaa aatctaactt
     3721 cgtagtatat tatgggccaa taattcagaa ttatcaagca attttgaatt atttttttct
     3781 tattctgttc caatctagtt ttcatattct taaaaaagtg ataaaatggt aggaagaatt
     3841 ggagagtaga gatgccgaaa gaagtgaatt taacaggcga agaagttgtc gctttaacca
     3901 aagaatattt aacggaagag gatgttcatt ttgtccataa ggccttggtc tatgctgttg
     3961 aatgccacag tggtcaatat cgcaaatcag gcgagcctta tatcattcac cctatccaag
     4021 tggcaggtat tttagctaag ctaaagctgg atgctgtaac agtagcttgt ggattcttgc
     4081 atgatgtggt ggaagataca gatgcgacct tggacgattt ggaaagagag tttggtcctg
     4141 atgtgcgggt gattgttgac ggagttacca agcttggcaa ggtcgagtac aaatcgatcg
     4201 aggagcaatt agcggaaaat catcgcaaga tgctcatggc catgtctgag gacatccgcg
     4261 ttattttggt caaactgtct gaccgcttgc acaatatgcg gaccctgaaa catcttcgaa
     4321 aagacaagca ggagcgtatt tccaaagaaa ccatggaaat ctatgcccca cttgcccatc
     4381 gtttggggat ttccagtgtc aaatgggaat tagaagactt gtctttccgt tatctcaatc
     4441 caacggagtt ttacaagatt acccatatga tgaaggaaaa gcgcagggag cgtgaggcct
     4501 tggtggatga ggtagtcaca aaattagagg agtatacgac agaacgtcac ttgaaaggga
     4561 agatttatgg tcgtcccaag catatttact caattttccg caaaatgcag gacaagagaa
     4621 aacggtttga ggaaatctat gatctgattg ctattcgttg tattttagat acccaaagtg
     4681 atgtttatgc catgcttggt tacgtgcatg aattttggaa accgatgcca ggtcgcttca
     4741 aagactatat tgccaaccgc aaggccaatg gttatcagtc tatccatacg actgtttatg
     4801 gaccaaaagg gccgattgaa ttccagattc gaaccaagga aatgcacgag gtggctgagt
     4861 acggggttgc ggctcactgg gcttataaga aaggtataaa ggggcaagtt aacagcaagg
     4921 aatcagctat tggaatgaac tggatcaagg agatgatgga gctccaagac caggctgatg
     4981 atgctaagga atttgtggac tctgttaagg aaaactattt ggctgaggag atttacgttt
     5041 ttaccccaga tggagctgtc cgttcccttc ccaaagattc aggaccgatt gattttgcct
     5101 acgaaatcca taccaaggtc ggtgaaaaag caactggtgc caaggtcaat ggccgcatgg
     5161 ttccactgac aaccaagtta aagacagggg atcaggttga aattatcgcc aacccgaact
     5221 cctttggacc tagccgtgac tggctcaata tggtcaagac tagcaaggcg cgcaataaga
     5281 ttcgccagtt ctttaaaaac caagataagg aattgtctgt caacaagggt cgtgagatgc
     5341 tgatggctca gttccaagaa aatggctatg tggcaaataa atttatggac aagcgccaca
     5401 tggatcaagt tctgcaaaag accagttaca agacagaaga ctccctcttt gcggccattg
     5461 gttttgggga aatcggtgcg attaccgtct ttaatcgtct gactgaaaag gaacgccgtg
     5521 aggaagagcg tgccaaggcc aaggctgagg cagaggagct tgtcaaaggt ggcgaggtca
     5581 aggttgaaaa taaagaaact ctcaaggtca agcatgaggg gggagtggtt attgaaggtg
     5641 cttctggtct cctagtgcgg attgctaagt gttgtaaccc cgtgcctggt gacgatattg
     5701 ttggctacat taccaagggt cgtggtgtgg ctattcaccg tgtggactgt atgaacctgc
     5761 gtgcccaaga aaactacgag caacgtctcc ttgatgtgga atgggaagac cagtactcta
     5821 gctcaaataa ggagtatatg gcccatatcg atatctacgg tctcaaccgt acaggactgt
     5881 tgaacgatgt actgcaagtt ctttcaaata caaccaagaa tatttcaacg gtcaatgccc
     5941 aaccaaccaa ggatatgaag tttgctaata tccatgtgtc cttcggtatt gccaacctct
     6001 ctacactgac cacggttgtc gataaaatta agagtgtgcc agaagtttac tctgtcaaac
     6061 ggaccaacgg ctagttgtcc tagctcttac tagaaaggct attatgaaaa tcattatcca
     6121 acgggttaaa aaagcccaag tgagtataga aggccagatt cagggaaaaa tcaatcaggg
     6181 acttttattg ctggttggtg ttggaccaga ggaccaagag gaagatttgg actatgctgt
     6241 gagaaaactg gtcaatatgc ggattttttc agacgcagaa ggcaagatga acctgtctgt
     6301 caaagatatt gaaggagaaa tcctctctat ttctcagttt accctctttg cggatactaa
     6361 gaaaggcaat cgtccagcct ttacaggggc agctaaacct gatatggcat cagacttcta
     6421 tgatgctttc aatcaaaaat tagcgcaaga agtgcccgtt cagacaggta tctttggagc
     6481 agatatgcag gttgagctgg ttaataacgg acctgttacc attatcctag atactaaaaa
     6541 gagataagaa agaccaagcc cagtcggctt ggtctttctc atctatcata aaatactcca
     6601 aaaagaaatc ggttcttgat atgcttgggg gaagtctctt ttcaggcttt ggcagatgcg
     6661 ataggaaggg atgagatgtc ctaggatgag gagagttccc tgaaggaaaa gtggaatatc
     6721 acttaaagac accaaggaga gaatcatcag gctatcccat aggagaattt gtaaagcaaa
     6781 acgccagaat ctcggtctaa tctgggaata gagttaacta aagtggtcac aaagttggtt
     6841 tgaaagatag gtcaatagca caggatgaaa gaaaatgagc caaccgctat aaatcaaaat
     6901 ccagtcccaa gtaagccccc ttttaaatgt caaaaatgcc agcatgattc catcaatgac
     6961 aaggagttga atggttttga tgaagatgat ttttttcatg ctaaaacctc cttttcctta
     7021 gagacactcc cataaagaga tgtgtttgtc gtaaaagtct ggatagtttt ctcttaggta
     7081 gtcagctgtc atataataaa aagtagaatg gcaagcagtg ataattgaca taagagatga
     7141 aaaacgctga gaactaatga aggctaagag aacaaaaaat agaaaatcaa tggtgagaac
     7201 ccctaaatag tagaagcgaa tctttttatt gatttgagga taaatctcag cgaattgatg
     7261 tttgagtcgg acgatcaaga gaaatagcag gagtccttga gcaaggaaga aaattaaacc
     7321 agagagcaag agccactcaa aagatgtctc gagtctaatg ataaaaaatg caaatagtag
     7381 caaatcaata actgcaattg ctataaaatg gattctatag agttttttca tgacaagacc
     7441 tccctctttt atctaacttc attctactcc aaaagaatgg gagttacaac taaaatgata
     7501 aaaatagcag aagggagatt ctcttaagtt ggctagtatt ctttatttga gtttccttct
     7561 attatctaac ttcttcatca ttccagacaa ataaagctcc gattgcattg aggatataaa
     7621 agatgtattt accgatattg gcgaagtttc cttgaatacc agcttttgtc agctgaacga
     7681 aattgtaaat caaccaaaag ccccactgag ttgttagttt taatgcattc aaagcattgg
     7741 caatgaggga tagtgcaaag gcaatagttg ttacgtaggc aaggagattc atcttgccct
     7801 catatccgat atagttggtc acaaaggcaa agaggaaggc gatgatggaa atgatgatga
     7861 ccgccaattt tacctgtttt tggcttattt ggttgggtct gccttcttgc gaagctttcc
     7921 atttctttat agcaaaggta taaatgagga aggtgacggg ataggtaatg atggccgcct
     7981 tatttccaag gatataatca atagcaccgg acaaaatggt attaacaata ccaaagtaat
     8041 ttccccattt gcttaatttc cccgtgaaac gagtggacaa catggaaatc ccaacgttgg
     8101 ttacggaaat caatccaaag ggtacaagag ctgtccatag tccccagtct acaaatttat
     8161 cgaggcgtga gttgagataa ccagatgcaa tcgcaatccc aacgaccaaa gcaaccccga
     8221 agaggtcaaa ccatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     8281 cctttctttt tttttcaaat attctaccac caaatgaaag taaaataaaa tgatagaaat
     8341 aaaaccctga aaataaaact ttcagggttg gtaggggact tgagaaatta gttgattttc
     8401 tcgacataga gttgttttgc aatgaccata ttcacttgta aatcctcgtc gttactgagg
     8461 atagtgaagg tattgctgaa gccatcaaac tgcttgactt ggagctggtc accgatgtga
     8521 agtgagtgct tgtccagata atggagaatg tcaaaactat cgtgcacccg agtcaggcgg
     8581 taggcgccag cttccttgat atcagctagt gggaggttat tgatttcaac gaggagttct
     8641 cccttggcag gaatagttcc tccgtggggg caggttttag ggaaacctag cagtttatct
     8701 agtctttcca cgaacaggtc agagacagtg tgttccaaga cctcagcttc ctcgtgaatc
     8761 tggtcacttg tatagtctaa atgatgaact agaaaaactt caatcaagcg gtgcttacga
     8821 tagagctcag agaccagttt gagaccgagg tcagtcagta gatagccaca ttccttgtcc
     8881 tttaggatga gattttcact tttcattcgt ttgatcattt cagttacggc agggggagag
     8941 acttgcatgc gagccgcaat ttccttgttg gtaatcttat gcaggtctat gccaatttca
     9001 taaatacatt ttagatagtc ttctttgttt ggggtcattc gtttcctctt gtctaatatc
     9061 tttatctagt atatcaaaaa aagctagatt tctctagctg tgacttttta tgttatactt
     9121 attgcaagag aaaaaacgag gagatggata tgacgaaaat agctcttctt tcagatattc
     9181 atggaaatac caccgccttg gaggctgttt tggcagatgc tcggcagcta ggagtggatg
     9241 aatactggct tttgggagat attctcatgc cagggacagg acgtagaagg attttggact
     9301 tgttggatca actaccgatt acggctagag ttttgggaaa ctgggaagac agtctttggc
     9361 atggtgtccg taaggaattg gatagtactc gccccagtca acgctatctc ttgcgccagt
     9421 gccagtatgt tttagaggaa atttccctag aagaaattga agtgctccac aatcaacctc
     9481 ttcaacttca tcgtcagttt ggggatttga cggtgggaat tagccatcat ctgcctgata
     9541 agaactgggg gcgagagttg attcatactg gcaaacaaga ggagtttgac cgcttggtga
     9601 ctcatcctcc ctgtgatatt gctgtttatg gacatattca ccagcagttg cttcgttacg
     9661 ggactggtgg gcaattgatt gtcaatccgg gttcgattgg ccaacctttc tttttggacg
     9721 ctcagctacg gaaggacttg cgggcccagt atatgatttt ggagtttgat gacaagggcc
     9781 tggtagatat ggacttccga cgggtagact acgatgtggc agctgaattg cagctggcta
     9841 aagacctgag acttccctat tttgaggttt attatgaaag tctggtcaat gggatccacc
     9901 atactcatca tcaggaattt ttgagagaat tggctcagaa agagggctgc gatcgggagt
     9961 tagacgactg gttgaaaagt ggtaacgatt gacattacaa ctaaaaaggg tataataata
    10021 gaaaaagaag agtagaggca gggtagcctc gtaaaaagga gaagaggatg caaattccaa
    10081 gtagatttac cattgcgact catatgctga taatcattgc cctcgagggg aaggaaagca
    10141 aggtgaccag tgattttctg gctgctagtg tcggggtcaa tcctgtcatt atcagaaaga
    10201 tcttgtccca gttgaagaag gcagagctga tttcagtagc gcgtggaacg ggcggaacag
    10261 agattgtcaa ggaccttaag gatattagtc ttttagatgt ttatcaggcg gtcgaatgtc
    10321 ttggtaagac aggtcaactc ttcagtttcc atgacaatcc gaatcccaat tgccctgtag
    10381 gagctcatat tcatgatgtt ttggatcaaa aattggagag aattcagttg actatggagg
    10441 cagaacttgg tcagaccagt ctagaaaaag tcgtggccga tgcagagagt cagatgaagg
    10501 attaagaggg ataaatgccc tctttttttc tttggataat tatgataaaa tgtagctatt
    10561 aaaggagtaa gaaatgtatc ttgttatagg aattgtatta gcctttatag tgtcattttg
    10621 gaaggataat agaagtttgt ggaatccagt attattttta ttatccttca tttcaagtta
    10681 tttttatcta tcctaccttt tttataaaaa tggatacgag aatgttcagt tagcttttta
    10741 tgtatttgcc tttgtcttac ttcctttttt gctttttcta agtggcatct ttttaatcta
    10801 taatggggtc attttgttga aacgagaggg acgttccaag ccccattatc tctcaatgct
    10861 ctttgatttt tattgactat tagattctat ttaaaaagac ttagaatgca catgaaagta
    10921 tgtattctag gtcttttgtt ttgtatacat ttaattttca agagtattat ctatttttcc
    10981 atgcatggta acgagtatca atcaataact gggtaaggcg acccaaggtt tctctttctt
    11041 ttggagtgag ggattgagct tggacaaaga gatgatgaat gtattcaagc gcctttaagg
    11101 aagccaagtc attgatagag ctaataccag catcaagaat agtgccaaag aagaggtcga
    11161 agtagagctg aagttcttcg tcagggactg tggccaccca ttctttaaag gttgtgtcta
    11221 cttgccggct atcactgttg gtcttatcca gttgaacgaa gtgcttgtcc tcaatctgcc
    11281 aactaaaggt atcgtgctgg gcgatgccac ccagggcagt actctgaacg atgatttggt
    11341 gagcaggaat ttccagcatc ataccgataa tggaaccttg tggaatgaat atcttgcttc
    11401 tatccattat cctttgataa cccgcagtct gtgtcaattc ttgatggaga ccaggtgcat
    11461 caaatgtata aactgctgtg atctgatttt gcaaactttg ctcaatttgg ctagcagcat
    11521 agatagcgag atttcctccc ttggaatgcc cagccagaat aaccttttgc ttaggatgat
    11581 gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg agaaggaatt tccttcatat
    11641 aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc atctgtccca cgaaagacaa
    11701 tcagataggt atcgaggctg acacgataag tcatagccgc aaattgcttt tgcagttcag
    11761 ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt gaagcgcttg tgttgagcca
    11821 attcatctaa taattgaagg cgatttttgc tagtaagcat ggtgggctct cttggaacct
    11881 gaggtgctag atctaaaaga cgttgaggaa gtgtggagac cagattatca aaggagaggt
    11941 aggtgatttc tattaaggtt agaatgtcta actcattcaa gggaaggtcg taataagaat
    12001 catatgcgac atctttcaga tagtcaaaaa tattggccat aagagctcct ttctttttat
    12061 ttatcttagc aaatttccct caaattagct agtagcatag cctgtttgtg ctggctaaaa
    12121 acaggctatt tcaaattcag tttcagacca tctagcatgg aaaaatctgt tataataatg
    12181 gaaaaggaga agcgcatgca caagatttta ttaatagaag atgatcaggt cattcgtcaa
    12241 cagattggga aaatgctctc tgaatgggga tttgaagtgg tcctggtaga agactttatg
    12301 gaagttttga gtctatttgt tcagtcggaa cctcatctgg tcctcatgga tattggtttg
    12361 cccttgttta atggttatca ctggtgtcag gaaatccgca agatttccaa ggtacctatc
    12421 atgtttcttt cttcgagaga ccaggctatg gatattgtca tggcaatcaa tatgggggcg
    12481 gatgactttg tgaccaagcc ttttgaccag caggttcttt tagctaaggt tcagggcttg
    12541 ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc tggaatatgc tggtgttatc
    12601 ctcaatacca aatccatgga tttacattat caagggcaag tcttgaattt gaccaagaat
    12661 gaattccaga ttttacgcgt gttatttgag catgcaggca acatcgtagc acgtgacgac
    12721 ctgatgcggg aactttggaa cagtgacttt ttcattgatg ataataccct ctctgtcaat
    12781 gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg taggatttat cgagaccaag
    12841 aaaggaatag ggtatggatt gaagcatgct tgattggaaa caattttttc tagcctatct
    12901 gcgctcccgt agtcgtcttt ttatctatct gctttctttg gcatttcttg tcttactctt
    12961 tcagttttta tttgccagtc taggaattta cttcctctac tttttcttct tgtgttgctt
    13021 tgtaaccata ttatttttca cttgggacat attggtggaa acgcaggtct atcgccagga
    13081 acttctctat ggagagaggg aagccaagtc tcctttggaa atagctttag cagaaaaatt
    13141 agaagcgcgt gagatggaac tctatcagca gaggtcaaaa gcagaaagaa aactgacgga
    13201 tttgctggat tactatacct tgtgggtcca tcagataaag acccccattg cagccagtca
    13261 actcttagtt gcagaagtgg tcgaccgcca actgaagcag cagctagaac aggaaatttt
    13321 caaaatcgac tcctatacca acctagtttt acagtacctg cgtttagaaa gtttccatga
    13381 tgatttggtc ttaaagcagg ttcaaattga ggacttggtc aaggaaataa ttcgtaaata
    13441 tgctcttttc tttattcaaa aaggcttaaa tgtcaatcta catgaccttg ataaagaaat
    13501 cgtgacggat aaaaagtggc tgctagtggt tattgagcaa atcatctcaa acagtctcaa
    13561 gtacaccaag gaaggtggtc tggagattta tatggatgac caagagcttt gtatcaaaga
    13621 tacgggaatc gggataaaaa acagtgatgt cctccgagta tttgaacgtg gcttttcagg
    13681 atacaatggc cgtttgaccc agcagtcctc tggacttggc ctttatctat ctaagaaaat
    13741 ttctgaagaa ctggggcacc agattcgtat cgagtctgag gtcggaaaag gaacgacagt
    13801 gcggattcag tttgctcaag tgaacttagt ccttgagtaa aaatagatga gaaaaagcct
    13861 ccagattgga ggcttttatg ctagactctt atttctcaac gcgtgatttg ttggcgatat
    13921 cagctaggat agcttgaaca aaattatcaa ctgagacagt ttgtgtttct ttttggccgt
    13981 agcgacgaac gttgactgtt tcgtcttcca tttctttgtc tccaacaatt aattggtaag
    14041 gaatcttgct agtttgtgaa gcacggatct tgaactgcat tttttcattg cgctcatcta
    14101 cgtctgcacg gacaccgcgg tcacggagtt tcttggctac ttcccaagcg tagtccacgt
    14161 gtttttcgtt agatactggg ataagggtta cttggtgtgg tgccagccat gttgggaagg
    14221 cacccttgta gttctcaatc aagatagctg tgaagcgttc catagttgag ataaccccac
    14281 ggtggatcat gactggacgg tgatcttcgc catcagctcc gatgtatttg aggtcgaagc
    14341 gttctggcaa caagaaatca agttggatag tagaaagggt ttcttctttt ccaagggcag
    14401 ttttaatctg gatatccaat tttggtccgt agaaggctgc ttcaccttcg gcttcaaagt
    14461 agtccacgcc catttcatca agggctgcac gaagcatggt ttgggcattt tcccacatct
    14521 catcgttatc aaagtactta tgagtatctt gagggtcacg aagagagagg cggaagcggt
    14581 agtcagtcaa gttgaagtct tcataaacat cgataatcaa ctgaagggca cgttggaatt
    14641 cttcttggat ttgttctgga gtaacgaata ggtgaccgtc gttgagtgac atttcacgta
    14701 cacgttgaag gccagtgagg gcaccagatt tttcgtaacg gtgcatcata ccgatttcag
    14761 cgatacggat tggcaattca cggtaagagt gaacatggtg tttgaaaact tggatgtggt
    14821 gcggacagtt cattggacga aggacaaatt cttccccgtc acccatgtcc atggttggga
    14881 acatgtcttc ttggtaatga tcccagtggc cagaagtctt gtaaagctca acagaagcaa
    14941 gtggtggagt gtagacgtgt tggtagccag aagccaactc tttgtttacg atgtagcgtt
    15001 ccaattcacg acggatagtc gcaccatttg gcaaccagaa tggcaaacct tgtcccactt
    15061 cttgtgaaat cataaagagg tcaagctctt taccaagttt acggtggtca cgttccttag
    15121 cttcttcacg catttgaagg tagtttttca agtctttctt gtcaaaccaa gctgtaccgt
    15181 agatacgttg catcatagcg ttgtcgctgt ttccacgcca gtacgcacca gctacatgga
    15241 gaaggtggaa gatttggata cgacctgttg atggaacatg aggtccacgg cagaggtcta
    15301 catattcacc ctgacgatag atagtcaaac cgccttcgtc ttctgagtgt tcttcaatca
    15361 attccaactt gtaagggtca tttttgaaga tttcacgtgc ctcgtcttta gtcacttctt
    15421 cacgaataga tgggaagttt tctttgacga ttttttgcat ttcttcttcg atacgaggaa
    15481 ggtcttcgtt agagatttga ccagctgtgt tgtcagtatc gtagtagaaa ccatcttcga
    15541 tggctggacc aactcccaag tgaatgtctg ggaaaagacg acgagctgct tgggcgaaca
    15601 agtgagctgc tgagtgacgc aagattggaa gggcatcttc gtgatcaggt gtcacaattt
    15661 cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat gagtttgccg ttgaatttac
    15721 cagccaaggc ttttttagct agggaattgc tgatagattg ggcaatttca aaagttgtta
    15781 cgccagattc gaattcacga acagcgccat ctgggaaagt aatgttaatc atgatgttct
    15841 ccttttttat tatttcatag tttctaagca ttgatttttt atcagcagac tacttccaag
    15901 tcctaacgtt caattgcttt tctttatcag agaggaagtt ttccatttcc gtcagaatgt
    15961 ctatatccaa acgttgagaa agttctaata gtcaccagat attttctgaa agtttttgtt
    16021 ccagtgtgta gggtgtttca tcatagtagc gtccttgttt tgtcatcacc agtcgttgga
    16081 aatttccaat atcattagat aaagccaaga ggtcttcttc taccgtccac ttggaatcat
    16141 gatgcttaac ttccagttcg ttataagctt gtcggattgc ccaactgcgc tccactaatt
    16201 cttgcaactc cataattagt atcctaataa aaaaatgcga catcctcgaa aggacgtcgc
    16261 aacgtggttc caccttcatt tatgtacctc aaaagagagg gacacctctg attggctcta
    16321 acgtggccac cgttttatgt tttcataaaa aactcaagag tagtatcagt ttagacttcc
    16381 tatgcgtttc cagcaaccac gcactctcta gtagaaaggg actaagtgac ttgtctctat
    16441 ggattattat agcatgattg tgagattttt caaggatttt gtgaaagttt tttgtttttc
    16501 attttttgta gaatatgctt gatgctaata ccagaatcca tgcccaccag agcaactgtt
    16561 tcatagatta gcaagtaaat tagtataaac tcaccaaagg ttatgatagt aaagtaaaag
    16621 agcagtccgt taccaactaa ccatcaaagt gagaaacgga aacggtagct atagagtaac
    16681 gatacaatca agattaccag aggtgtaaag aagagaagat tgtttatata gtgtaagggg
    16741 gtcagaaaca actagcaaga acaactcata aagtggccaa taaaagaata atatgaccag
    16801 atagtagggg agatgggaat agaatctacg catgataatc acctcgtttt aaaaaaacag
    16861 acaacttaga tctcttgcta tgattattat agcatattta aaacaagaaa gtaaatttgt
    16921 tgacaaagaa gatttttttt cactagaatc atggttagtt ttcttggtag aaatattttg
    16981 ataataatta agcaagacta ttgacattga ttattaagag tgtcacaatt gctgtaacta
    17041 aaataattac aacaagagag gtataaaaaa tgaaactagc agttattgca gcaaatggac
    17101 aagcggggaa agcaattgtt gaagaagcag tcaaacgagg acatgaagta acggctattg
    17161 ttcgttctga aaacaaaagt caagctgagt ctattattaa aaaagattta tttgagttga
    17221 caaaagatga tcttactgga tttgatgctg ttatttcagc gtttggtgct tatacaccag
    17281 atacgctacc gctccatagc aaatcaatcg aactatttaa tcagcttctt gctggaacac
    17341 agacacgttt tctagttgta gggggagcag gaagccttta tatagatgaa acaaaaacga
    17401 cacgactttt agatacgcct gattttcctg aagaatttaa gccactagca aaagctcaag
    17461 cggatgaatt tgatcttctt cgtacaaaaa ataatctcaa ctggactttt gtcagtcctg
    17521 ctgtagattt tattcccgat ggtgaaaaaa caggaaacta cattctagca ggagaaattt
    17581 ttactactaa tggaaaagga ataagccaga ttagttatgc agattatgct attggattgg
    17641 tagatgaact tgaaaaaggt catcatataa aagaacgtat ctctttactt gaaaaataat
    17701 aactatgaga gtattaatgt ttgacagaaa atttaaatct tggtaaaata gggattgtcg
    17761 taaagacaaa taacttcttc ttggttacag gcatgccaac ctgtcactcg gatgaagcca
    17821 aataaaaagg agaaacatca tggcaatctc aaaagagaaa aaaaatgaaa tcattgcaca
    17881 atatgcacgt cacgaaggtg atacaggttc agtagaggtt caagttgctg tccttacttg
    17941 ggaaatcaac caccttaacg aacacatcaa acaacacaaa aaagaccacg ctacttaccg
    18001 tggattgatg aaaaaaatcg gtcgccgtcg taacttgctt gcatacttgc gtaaaaacga
    18061 cgttaaccgt taccgtgagt tgatcaactc tctaggactt cgtcgctaat tcaagataca
    18121 aaggccgtca aaagcacaaa gcaaaaatag gaaaattgac gaagaaactt cagtttctag
    18181 gagattttat cttttttgcc aagtgcttag gccgtgttca attgagcata tcttgataat
    18241 gaagctactc taaattgggt agcttttttg cgttgtcacc ttacctcgat atactcaagt
    18301 ataatctttg gttacggttc ctagcactgt aaggtaaaat aaaccagctt ttctcccttc
    18361 ggggagattt tttttgtttc actgaaagtt tcgtacgatc ttcgcctcgt cgcctagtct
    18421 ataaacgatt tatctagcaa gaatcatgat gctaagggcg tcaaaaatcc gtatgaaaat
    18481 agggaaatga cacagtgttc gatgagcaca aggagtttca tctttttcac taggatttta
    18541 gcccgggctc aaatcagctc tctgacttca gagggctttt ttattgaggt tttatcggta
    18601 acaattttgg agactacaaa aacctcaaac ggtatcagct aattacacca taaaggtgcg
    18661 cagttactcg gcttttcaag ccgagtaact gtatgcaagc ccctagaaga gcccactctt
    18721 tacaaagtaa agtatagtat gttatacttt acatggaagt agtcactgaa ttccagttag
    18781 aaattacttt gtaactacgt tttgaggagg agtaaaatgc tttcctacgt tcgacattac
    18841 ccactagcga tagctaaatt aatgtgtctg tgctctccta aaatctgctg atttattact
    18901 gactaataca ggagtttttt tttatgggac agacaatcat atctgctatt ggtgtttata
    18961 tttccaccag tatcgattat ttaattattt taattatttt atttgcacag ctatcacaga
    19021 ataaacagaa atggcatatt tatgcggggc aatatctagg cacaggctta cttgtagggg
    19081 cgagtttagt tgctgcttat gtcgttaatt tcgtgcctga agaatggatg gttggattgc
    19141 ttggtttaat ccctatctat ttagggattc gctttgcaat tgttggagaa gatgcggaag
    19201 aagaagagga agaaattatt gaaagattag aacaaagcaa ggcaaatcaa ctgttttgga
    19261 cagttacatt gctgacaatt gcgtctggcg gagataattt aggtatctat ataccttatt
    19321 ttgcttcgtt agattggtca cagaccctcg tggccttgct tgtgtttgta atcggcataa
    19381 ttatcttttg cgagattagt cgggtgttat cctctattcc gttaatattc gagacaattg
    19441 aaaaatacga gcgaatcatt gtgcccttag tattcattct acttggacta tacatcatgt
    19501 atgaaaatgg cacgatagag acttttctga tcgtgtagat ttttttgttt cactaggatt
    19561 ttagcccgag ctcaaatcag ctctctgatt ttcagagggc tttttcattg agtataaatg
    19621 gacaatctta aagttactct attgtagagt ggcttttgat ttgattagga gattcttata
    19681 aatatagtaa aatgaaacaa aaacaggaca aatcgatcag gacagtcaaa tcgatttcta
    19741 aaaatgtttt aagaagtaga ggtgtactat tctagtttca atttgatata taaatgaaaa
    19801 ccttagctgt ttggccaagg ttcatttctt ctatgcaagt tcttctcttt tcttatctgg
    19861 gttccagatg aagcttgcga taaagctaaa gatgatggtt aggatagcga ggataatagc
    19921 aaggatgagg gcagggatgc ggataaacca ccagagtgga tttggttttt tatcattgtg
    19981 ccattgtttc gtttcttcgt ccagacgttg gaattctgtt tgaatacgat tggcgactgt
    20041 ttcaatgcct tcatcattca ttttcttgat atctgagata tcgattggat ttccaaagtt
    20101 catatcgaca cgttcacggc taatcaagcc cttcaaagtc atgggaccgg tgtaggtaac
    20161 cggcatgata cggaccttgg ccattttggc aatcagtgct gcgcccccct tgacatcgtt
    20221 tgagtggcgg ctaccacttg gaaacatgat gagagagcgg tcactttttt tgagaacgtt
    20281 gataggatat ttgatggctg aggcgctggg attttcacgg tcgatgggaa aggcgccaca
    20341 catacgaatc caccaaccaa agatacggtt ggtaaagagt tctttttttg ccataaagat
    20401 gaactgtttt ggcttggtcg caaaggccat ataaacagga tcccaccagg tacggtgagg
    20461 cgcaactaaa atataatttt catcttgatt aggaatttta tcagtattat gatagtgagc
    20521 attgccattg atggaccata agagcaatac aactaatcca cgcaaataag tataaaacat
    20581 gcgatctcct tcgattgttt tcttgttatt attatacctt atcaaaggag ggctggcaaa
    20641 cttttccctt gactagatgc atatttggga tgaaattaga attctgttaa aaaaaatgat
    20701 ataatagaat ttatggataa aaataagatt atgggattaa cccaaagaga agtcaaggaa
    20761 agacaggctg agggtttggt caatgacttt accgcatcag ccagtaccag cacttggcaa
    20821 atcgttaaac gaaatgtctt tacccttttt aacgctttga actttgccat tgctttggcc
    20881 cttgcctttg tgcaggcttg gagcaatctg gtcttctttg ctgttatctg ctttaacgct
    20941 ttttctggga ttgtgaccga gctacgagcc aaacacatgg tggacaagct caatctcatg
    21001 accaaggaaa aggtcaaaac catccgtgat ggtcaggaag ttgctcttaa tcctgaagaa
    21061 ttagtgctag gagatgtcat tcgtttgtct gcaggagagc agattcctag tgatgccttg
    21121 gttttggaag gctttgcgga agtcaatgaa gccatgttaa cgggagaaag tgatttggtg
    21181 caaaaggaag ttgacggctt acttttgtca ggaagtttcc tagccagtgg gtcagtttta
    21241 tctcaagttc accatgtcgg tgcagacaac tatgctgcca aactcatgct tgaggctaag
    21301 accgttaaac ccatcaactc ccgtatcatg aaatcgctgg acaagttggc tggttttact
    21361 gggaagatta tcattccctt tggtctggct ctcttgctgg aagccttgct tttaaaaggc
    21421 ctgcctctca agtcatctgt tgtaaattcg tcgacagctc ttttgggaat gttgcctaag
    21481 ggaattgccc ttttgaccat tacttcgctt ttgactgcag tgattaagct aggtttgaaa
    21541 aaggtcttgg tgcaggagat gtactctgtt gagaccttgg cgcgcgtgga tatgctctgt
    21601 ctggacaaga cgggcaccat cacccaagga aagatgcagg tggaggctgt tcttccactg
    21661 acggaaactt acggtgaaga ggctattgcc agcatcttga ctagctacat ggcccatagt
    21721 gaggataaaa atccaacagc tcaagccatt cgccagagat tccaaggtca agtagtctat
    21781 cctatgctct ctaatcttcc cttctccagc gaccgcaagt ggggagccat ggagttagaa
    21841 ggtttgggaa tagttttctt aggggcacct gagatgttgc tggattctga ggtcccagaa
    21901 gccagagagg ccttggagag aggttcacgt gtcttggtct tagctctcag tcaggagaaa
    21961 ttagaccatc acaaaccaca gaaaccatct gatattcagg ctctagcctt gctggaaatc
    22021 ttggatccta ttcgagaggg agcggcagag acgctgaact atctccgttc tcaggaagtg
    22081 gggctcaaga ttatctctgg tgacaatcca gttacggtat ccagcattgc ccagaaggct
    22141 ggttttgcgg actatcacag ctatgtcgat tgttcaaaaa tcacggatga ggaattgatt
    22201 gctctggcgg aggagacagc gattttcgga cgtgtttccc ctcatcaaaa gaaactcatt
    22261 atccaaacgc tgaaaaaagc gggtcataca acagctatga ctggggatgg agttaatgat
    22321 atcctggctc ttcgtgaggc ggattgttct atcgtaatgg cggagggaga cccggcaacc
    22381 cgtcagattg ccaacctggt tctcttgaac tcagacttta atgatgttcc tgagattctt
    22441 tttgaaggtc gtcgtgtggt caataacatt gcccacatcg ctccgatttt cttgataaag
    22501 accatctact cattcttgct cgcagttatc tgtatcgcca gtgctttact aggtcggtct
    22561 gaatggatct tgattttccc cttcattcca atccagatta ccatgattga ccagtttgtg
    22621 gaaggtttcc caccattcgt tttgactttt gagcgaaata tcaaacctgt cgagccaaac
    22681 ttcctcagaa gatccatgct tcgtgcccta ccaagtgccc tcatggtcgt gtttagcgtt
    22741 ctttttgtga aaatctttgg aacgagtcaa ggttggtctg agttagaaat ctcaactctc
    22801 ctctattatc tcttggggtc aattggtttc ttatccgtat ttagagcctg catgccattc
    22861 actctatggc gagtcctatt gattgtctgg tcagtaggag gcttcctagc cacagctctc
    22921 ttcccaagaa ttcaaaaact gcttgaaatt gcaaccttaa cagaacaaac gttgcctgtt
    22981 tatggtgtca tgatgttggt ctttacagtg attttcatcc tgactagtcg ctatcaagct
    23041 agaaaataaa gaaagactgc aatctgtgga ttgcagtttt tttaggtaca agattgccag
    23101 ccgaaatgtg gtataataag aggtaataga gttttggaaa gtgagagaag atgatttcaa
    23161 agagattaga attggtagct tcctttgtgt cacagggggc tattttacta gatgtgggaa
    23221 gtgaccatgc ttatctgcct atcgagttgg ttgagagagg ccaaatcaaa agcgctattg
    23281 caggtgaggt ggtggaaggt ccctatcagt ctgcggttaa aaatgttgag gctcacggcc
    23341 taaaggagaa aatccaagtc cgtttagcca atggcttggc agcttttgaa gagactgacc
    23401 aagtgtctgt cattaccatt gctggcatgg gtggtcgttt gattgctagg attttagaag
    23461 aaggtttggg gaagttagct aatgtagagc gtttgatcct ccagcccaat aatcgtgaag
    23521 acgacttgcg tatctggcta caggatcatg gattccagat tgtagcagaa agcatcttag
    23581 aagaagctgg caagttttac gagattttgg tggtggaagc aggacaaatg aagctatcag
    23641 ccagtgatgt tcgctttggt cccttcttgt ccaaagaagt cagtccagta tttgtccaaa
    23701 aatggcaaaa agaagctgag aagctagagt tcgccctcgg acaaatccca gaaaaaaatc
    23761 tggaagaacg tcaagttcta gtagataaga ttcaagctat caaggaggtg ccccatgtta
    23821 gcaagtgaag tgatccaagc ttatgaagcc ttttgccctc aggaattttc tatggaggga
    23881 gacagccgtg gtctgcaaat tggcacttta gacaagggta tccaaagggt catggttgcc
    23941 ctcgatattc gtgaagagac agtggcagag gccattgaaa agggtgtgga cttgattatc
    24001 gtcaagcacg cgcctatctt tcgtcctatc aaggacttgc ttgccagccg tccgcaaaat
    24061 cagatttaca tcgacctgat taagcatgat atcgcagttt atgtcagcca taccaatatt
    24121 gatatcgttg aaaatgggct caatgactgg ttttgtcaga tgctaggaat cgaggagacg
    24181 acttatctgc aggaaacagg tccagaacgt ggaattggac gtattgggaa tattcagcct
    24241 cagacatttt gggaattggc ccaacaggtc aagcaagtct ttgacctaga tagccttcga
    24301 atggtgcatt atcaagagaa tgatttgcag aagcctattt caagagtagc aatttgtggt
    24361 ggaagcgggc agtctttcta taaggatgct ttggcaaagg gggcagatgt ctatatcact
    24421 ggcgacatct actaccatac tgctcaggat atgctgtctg atggcttgtt agcattggat
    24481 ccaggtcact atatcgaagt gctttttgtg gaaaaaatcg cagcactcct tactcaatgg
    24541 aaagagaaaa aaggctggga actagagatt ttacctagtc aagcatcgac caatcctttc
    24601 cgtcatatct agttagaaag tgaagacaat gaaaaaagtt gccattattg gagcaggaat
    24661 tgtgggagca acagctgcct actacctctc gagagaaagt gacttagagg tgaccgtttt
    24721 tgaccatgag caaggtcaag ccaccaaggc cgcagcagga attatcagtc cttggttttc
    24781 caaacgccgt aataaagcct ggtacaagat ggcgcgcttg ggggctgatt tttatgtgga
    24841 tttattagct gatttagaga aatcaggaca agaaatcgac ttttaccagc gttcgggagt
    24901 ctttcttttg aaaaaggatg aatccaagtt ggaagaactt tatcaactgg ccctccagcg
    24961 cagagaagaa tctcccttga tagggcaatt agccattctg gaccaagctt cagctaatga
    25021 attattccct ggtttgcagg gatttgaccg cctgctctat gcttctggtg gagcgagagt
    25081 agatggccaa ctcttggtaa ctcgtttgct agaagccagt catgtcaagc tggtcaaaga
    25141 aaaagtgact ctgacaccgt tagcatcagg ctaccagatt ggcgaagagg tgtttgatca
    25201 ggttattttg gcaacgggag cttggttggg ggacatgtta gagcctttag gttatgaagt
    25261 ggatgtccgt cctcaaaaag gacaactacg agattatcag cttgcccaag acatggaaga
    25321 ttaccctgtt gtcatgccag aaggggagtg ggatttgatt ccctttgcag gtgggaaatt
    25381 atccttgggc gctacccatg aaaatgacat gggatttgat ttgacggtag atgaaccctt
    25441 gctccaacaa atggaggagg ccaccttgac tcactatctg attttggctg aagctacttc
    25501 aaaatctgag cgtgttggaa tccgtgccta caccagtgat ttctctcctt tctttgggca
    25561 ggtgcctgac ttaactggtg tctatgcagc cagtggacta ggttcatcag gcctcacaac
    25621 tggtcctatt attggttacc atttagctca actgatccaa gacaaggagt tgaccttgga
    25681 ccctgaaaat tacccaattg aaaactatgt caaacgagta aaaagcgaat aatactcaat
    25741 gaaaatcaaa gaacaaacta ggaaactagc cgcgggttac tcaaagcact gctttgaggt
    25801 tgtggataga actgacgaag tcagtaacca tacccatggc aaggcgacgt tgacgtggtt
    25861 tgaattggat tttcgaagag tataagcatt ttactgaaat tttatcaggt agtttaggat
    25921 ggcaaatgac attccctgtc aaaaatggta aaataagaaa aaataatctg agaatcgagg
    25981 aaaaaagatg caagaaaaga ttttggtaac tggtggtgcc ggttttattg gaacccacac
    26041 tgttattgaa ttgatccaag caggccatca agttgttgtg gtggataatc ttgtcaatag
    26101 caatcgtaag agtttagaag ttgttgaaag aatcacagga gttgagattc ctttctatga
    26161 ggcagatatt cgtgacacag ataccctcag agatattttc aagcaggaag aaccgactgg
    26221 tgtcattcac tttgctggtt tgaaggctgt tggcgaatca acacgtatcc ctcttgccta
    26281 ctatgacaac aatatcgctg gaactgtcag ccttttgaaa gtcatggaag aaaacaactg
    26341 taaaaacatc atcttcagtt cttctgcgac agtttacggg gatccgcaca cagtgcccat
    26401 cttggaagat ttcccacttt cagtgaccaa cccatacggt cgtactaagc tcatgctaga
    26461 ggaaattttg actgatattt acaaagcaga ctcagaatgg aatgttgtct tgcttcgtta
    26521 ctttaaccca atcggagccc atgagagtgg tgatttggga gaaaatccaa acggtattcc
    26581 aaacaatctc ttgccatatg tgactcaagt agccgttgga aaattagagc aagtgcaagt
    26641 gtttggagac gattacgata cggaagatgg aacaggtgtt cgtgactata tccacgttgt
    26701 cgatttggct aagggtcacg ttgcagcttt gaaaaaaatc caaaaaggtt caggactaaa
    26761 cgtttataac cttggaactg gtaaaggtta ctcagttctt gaaattatcc aaaacatgga
    26821 aaaagcggtg ggacgtccta ttccttaccg catcgtagaa cgtcgcccag gtgatatcgc
    26881 tgcctgctac tcagatccag caaaagctaa agcagaactc ggttgggaag cagaactcga
    26941 catcacccaa atgtgtgaag acgcatggcg ttggcaaagc aagcatccaa atggatttga
    27001 agactaagat gatgatttca atcatcgtcc cttgtttaaa cgaagaggaa gtacttcctc
    27061 ttttttatca ggctctggaa gctttacttc cagatttgga aacagaaatc gagtatgtct
    27121 ttgtcgatga tggatcgagt gatgggacct tggaactctt aaaggcctat cgggagcaaa
    27181 atccggcagc ccattatatt tctttctcgc gaaattttgg caaagaagca gccctttatg
    27241 caggcttgca atatgcgaca ggagatttgg tggtggtgat ggatgcagac ctccaagatc
    27301 ctcctagtat gttgtttgag atgaaaaatg tactagacaa aaatgtagac ttggactgcg
    27361 ttgggacacg gagaactagt cgggagggag aacccttctt tcgcagtttc tgtgctgttc
    27421 tcttttatcg cctcatgcaa aaaatcagcc cagtagctct gccgtcgggt gtccgtgatt
    27481 ttcgtatgat gagaaggtct gtggtcgatg ccattttaag cttgactgag tccaatcgtt
    27541 tttcaaaggg gctcttcgcc tgggtgggtt tcaaaaccta ctatttggac tatccaaatg
    27601 tcgaaaggca ggctggcaag accagttgga gttttaggca actctttttc tactccattg
    27661 aagggattat taatttttca gattttccct tgattatagc ctttgtagct ggtctcctat
    27721 cttgttttct ttctctgctg atgacctttt ttgttgtggt tcggaccctc attttgggca
    27781 atccgacatc tggttggacc tctctgatgg ctgttattct ctttcttgga ggcattcaac
    27841 tcttgaccat tgggattctc ggaaagtata tcagtaagat ttatttagag actaaaaaaa
    27901 gaccacttta tcttatcaaa gaaaaaagtg accttcctga ttttacagaa aaaaataaag
    27961 tgaaaagact ataattttac atggaaatat gctaaactag agggagtgga ttatcgccat
    28021 tgatttaggc ttcctggttt ccaatcaggg cgcgagttgg gcaattttta acagcctcta
    28081 agacatcctg actaggagaa atttcttttt ccagttggtc agggtcatcg taaaaacgca
    28141 cgattccatt atcgtggtaa tcaaataaat cagaataagt ttggcaaagc ccacaggcga
    28201 tacatcgttc aggtataagt gtgattttca tgttcatatt tatattgtaa taagaaaagt
    28261 aaaaaaaaac aaggagtaag gtatggcaaa agaaccgtgg caagaagata tctatgatca
    28321 agaagaatca agagcagagc gtcggcatcg aaaccacgga ggggctgata ggatggctaa
    28381 tcgtattttg acgatcctag ctagtatttt ctttgtaatt gtggtggtga tggtcatcgt
    28441 tctcatctat ctatcatcgg gggggagtaa tcgcacagca gccttaaaag actttcatga
    28501 ttctgatgca agtgtagtac aaatctcatt ttcaagcagt tctcagcctg agcagagttc
    28561 agagctagaa tctacttcta gtagttcaga agaagctgct aatcctgaag gaacgattaa
    28621 agttctcgca ggagaagggg aagcagctat tgccgctcgt gcaggaatct ccattgctca
    28681 gttagaggcc ttgaatcctg ggcacatggc tacaggatct tggtttgcta atccaggtga
    28741 tgttataaaa ataaaatagg agccgatatg aaaacaattc aaattgctat tgatggtcct
    28801 gcttccagcg gtaagagtac ggtcgcaaag attattgcta aggattttgg attcacctac
    28861 cttgatacag gagctatgta tcgtgcagcg acctatatgg ctcttaagaa ccaattagga
    28921 gttgaagaag tcgaagccct tctagccttg ttggaccagc atccaatcag ctttggacgt
    28981 tcagaaactg gagaccagct tgtttttgta ggagatgtgg atattaccca tcctatccgt
    29041 gaaaatgaag tgaccaatca tgtttctgct attgcagcaa ttcctgaagt gcgtgagaaa
    29101 ctggtttctc tccaacaaga aattgcccag caaggcggga ttgtcatgga tggtcgcgat
    29161 attggaactg ttgtattgcc acaagcagaa ttgaaaattt tcctagtagc ttctgttgat
    29221 gagagagcag agcgtcgtta caaggaaaat attgccaagg gaattgaaac agaccttgaa
    29281 accctaaaaa aggaaattgc tgcgcgtgac tacaaggata gtcatcgtga gacttctcct
    29341 ctcaaacaag cagaggatgc tgtctacctt gatacaactg gtttgaacat tcaagaagta
    29401 gttgaaaaaa tcaaagcaga agctgaaaaa agaatgtaaa tgtagaaaag ccgatagatt
    29461 gatatcggtt tttttctaaa tttgtcaaaa tgctgatttt agggtataat agttgctgtt
    29521 cgagaaattt tgattttcaa agaatagtga atgatgataa ggagaaacca tgaacaattt
    29581 accaaattgt ccaaaatgta actcagagta tgtctacgaa gacggtgccc tactggtttg
    29641 cccagagtgt gctcatgagt ggaatcctgc tgaagttgca gaagtagaag aaggtcttgt
    29701 cgctatcgat gccaacggaa ataaattgac tgatggtgat acagtaactc tcatcaagga
    29761 cttgaaagta aaaggtgcgc caaaagattt gaaacaaggg acgcgcgtga aaaatatccg
    29821 catcgtagaa ggcgaccaca atatcgactg taagattgat ggttttggtg ccatgaaact
    29881 taaatcagag tttgtgagga agatttaagc atgtcaaaac actataaact tgtattttat
    29941 agccgtatct tcttgtttct agcggctttt acgggagttt atcttgaaat tactaggcat
    30001 ggtggttttg ggatgcttct ctattacacg gttctgtcca acctcttggt aactattttt
    30061 accctttatc ttctaaaggt tatgagccgt gtaggtgaaa attggcaaag gccaagtctc
    30121 ttgcgcttaa aaggtggggt caccatgagt atcatgatta cctgtgtgat ttaccatttc
    30181 ctcttggcgc ccattgcgac taatttctat accctagaaa atttcctttg ccactatatc
    30241 gttcccatct ggtttttagc ggataccctc ttttttgaca aacagggtca atacaagatt
    30301 tgggatccag cagtgtggac cattttaccc tttctgtata tgatgtttgc tctttttaat
    30361 ggcttggttc taaaactcaa tattccaaat gccaaggata atcctttccc ttacttcttt
    30421 ttgaatgtga acaagggttg gaatgttgtg tttaagtggt gtctgattat ctttgttgcc
    30481 tatatggtag caggatttat tttctacttt atcaagcaaa tcaagagaaa gtcatcctaa
    30541 tactcttcga aaatctcttc aaaccacgtc agtttccatc tgcaacctca aaacactgtt
    30601 ttgaacaacc tgcggctagc ttcctagttt gctctttgat tttcattgag tataagatac
    30661 aagggattca ttttcgaatt taagaaggag tctacaaacc aatgaggctt cttcttttct
    30721 tgcttatttg ataactatca aaaaagtaga agattaagag aaatatagaa agagatttca
    30781 tgaaacaatt tttagaacgg gccagcattt tggctctctc cctcgttttg attacctcct
    30841 tttccatttc gagtgctcta ccagccatgt ttgactatta tcagggttat tctaaggaac
    30901 aaattgagct cttggtgagc ttgccttcct ttggaatcat gatgatgtta ctgctaaatg
    30961 gtttcttaga aaaaatattt cctgagcgct tacagattag tttgggcttg ctgattttat
    31021 cattgagcgg tacagctccc ttctggtacc aagcctatcc ctttgtcttt ggaacacggc
    31081 ttctctttgg tttgggtctt gggatgatca atgccaaggc catttctatt atcagtgaac
    31141 gctaccaagg aaaaaggcga attcagatgt tagggctacg cgcttctgca gaggtcgttg
    31201 gagcttctct cattaccttg gccgtcggtc agttgttggc ctttggttgg acagctatct
    31261 ttctagccta tagtgctgga tttttggtgc tgccccttta tctgctcttt gtcccttatg
    31321 gaaaatcaaa gaaagaagtc aagaaaagag cgaaggaagc aagtcgttta actcgagaaa
    31381 tgaaaggctt gatttttacc ttagctatcg aagcggcagt tgtagtttgt accaatacag
    31441 ctattaccat ccgtattcca agtttgatgg tggaaagagg attgggggat gcccagttat
    31501 ctagttttgt tcttagtatc atgcagttga tcgggattgt ggctggggtg agtttttctt
    31561 tcttgatttc tatctttaaa gagaaactgc tcctctggtc tggtattacc tttggcttgg
    31621 ggcaaattgt gattgccttg tcttcatcct tgtgggtggt agtagcagga agtgttctgg
    31681 ctggatttgc ctatagtgta gtcttgacga cggtctttca acttgtctct gaacgaattc
    31741 cagctaaact cctcaatcaa gcaacttcat ttgctgtatt aggctgtagt ttcggagcct
    31801 ttacgacccc atttgttcta ggtgcaattg gcttactaac tcacaatggg atgttggtct
    31861 ttagtatctt aggaggttgg ttgattgtaa tctctatctt tgtcatgtac ctacttcaga
    31921 agagagctta ggattgattc ctaagttttt cttttgatac tcaatgaaaa tcaaagagca
    31981 tagttgattg agtttggaat agtacgctgt agttgctaaa atatttctag aaattaattt
    32041 gacttttcta atagagttat tcatatctta tttcaatcta ctatagaaag ctagccgcag
    32101 gttgctcaaa atagtgtttt gaggttgcag atggaaactg acgtggtttg aagagatttt
    32161 cgaagagtat gagattttta tacccataca atatttgttt taggtccttg tttacagact
    32221 aatttcttga taaaatagag gttatgacga gatataaagc aactatttcc tatgatggtt
    32281 atgcctttgc tggctttcag cgccagtctc atgcgcgtag cgttcaggaa gaaattgaaa
    32341 aaaccttgac cagattaaat aaagggcaaa ccattactgt tcacggtgct ggtaggacag
    32401 atagtggggt tcatgccctg ggacaggtca ttcattttga cctgccttat cagatggatg
    32461 aggagaaact ccgttttgcc ttggataccc agtctcctga agatattgat gtgatttcga
    32521 ttgagcttgt ggcagatgat tttcattgcc gttatgccaa acatagcaag acctatgagt
    32581 ttattttgga tagaggacgt cccaaaaatc ctatgcgccg tcactatgcc acccactttc
    32641 cctacccact cgatgtggaa cgaatgcaga ttgcaatcaa aaagctagag ggaacccatg
    32701 attttaccgg ttttacagcc tctgggacta gtgtagagga taaggttcgc accatcacag
    32761 aagctagttt aatagtcgat gagacaggac aatttttgac ctttaccttt tcaggaaatg
    32821 gtttcttgta taaacagatt cgcaatatgg tggggactct tctcaaaatc ggtaacaacc
    32881 gcatgccagt agagcagatt gatctcatct tggagaagaa ggacaggaaa cttgcaggtc
    32941 ccactgcagc accaaatggt ttgtatttaa aggagattcg ttatgaagaa taatcgtatt
    33001 ttagcacttt ctggaaatga tatttttagt ggtggtggac tgtcagctga tttggctacc
    33061 tataccttga acggcttgca tgggtttgta gcagtgactt gtttgacagc cttgacagaa
    33121 aaaggatttg aagtctttcc aactgatgat accatttttc aacatgaatt agatagcttg
    33181 cgtgatgtgg aatttggggg aattaagatt ggtcttctcc ctactgtcag tgtggctgag
    33241 aaggccttgg actttatcaa acaacgccca ggagtacctg tggtgttgga tcctgtcttg
    33301 gtctgcaagg aaacgcatga tgtagctgtc agtgagctct gccaagagtt gattcgcttt
    33361 ttcccttatg tcagtgtgat tacgcctaat ctcccagaag cagaattatt atccggtcag
    33421 gaaattaaaa ccttggaaga catgaaaact gcagcgcaga aattgcatga tttaggagcg
    33481 ccagcagtca ttatcaaggg aggcaatcgt cttagtcagg acaaggctgt ggatgtcttt
    33541 tatgatggac agacctttac tatcctagaa aatccagtta tccaaggcca aaatgctggt
    33601 gcaggttgta cctttgcctc tagcattgcc agtcacttga ttaaaggtga taaacttttg
    33661 ccagcagtag aaagctctaa ggctttcgtt tatcgtgcta ttgcacaagc agatcagtat
    33721 ggagtaagac aatatgaagc aaacaaaaac aactaaaatc gcccttgtat ccctattaac
    33781 cgccctttct gtggttctag gttatttctt aaaaatccca acacctacag gaattctaac
    33841 tcttttagat gctggtgtct tctttgcggc cttttacttt ggtagtcgtg aaggagcggt
    33901 agtcggagga ctagcaagtt tcttgattga cctcttatca ggctaccctc agtggatgtt
    33961 ctttagcttg gtcaaccatg gcttgcaggg atttttcgca ggatttaaag gaaaaagtca
    34021 gtggttaggc cttattttag caactattgc catggtagga ggctacgcct tgggttctac
    34081 tttgatgaat ggctgggcag cagccctccc agaaattcta ccaaatttca tgcaaaatat
    34141 ggtagggatg attgtaggat ttattcttag tcaaagtatc aagaagatta agtaatactc
    34201 ttcgaaaatc tcttcaaacc acgtcagttt ccatctgcaa cctcaaaaca ctgttttgag
    34261 cagcctgcgg ctagctttct agtctgattt tcattgagca taaagaggtt gagtaaaaag
    34321 tctttcaaat aagaaaaacg catagtatag gatgttgaaa tgatgaactg ccccccaaaa
    34381 gttagacaga aaaaatctaa cttttggggt gtttttatta tgaaactaac ttatgatgat
    34441 aaagttcaga tctatgaact tagaaaacaa ggatatagct tagagaagct ttcaaataaa
    34501 tttgggataa acaattctaa tcttaggtac atgattaaat tgattgatcg ttacggaata
    34561 gagttcgtca aaaaaggaaa aaatcgttac tattctcctg tttaaaacaa gaaatgatt
//
LOCUS       DBERDS010000019        32557 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.019, whole genome shotgun sequence.
ACCESSION   DBERDS010000019 DBERDS010000000
VERSION     DBERDS010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32557
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.019"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..278)
                     /gene="tnpB"
                     /locus_tag="ACL73E_001049"
     CDS             complement(<1..278)
                     /gene="tnpB"
                     /locus_tag="ACL73E_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0801032.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWLSTEKDVKALAPE"
     gene            complement(259..444)
                     /locus_tag="ACL73E_001050"
     CDS             complement(259..444)
                     /locus_tag="ACL73E_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801033.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(748..2310)
                     /gene="guaA"
                     /locus_tag="ACL73E_001051"
     CDS             complement(748..2310)
                     /gene="guaA"
                     /locus_tag="ACL73E_001051"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGS0801034.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2452..3150
                     /locus_tag="ACL73E_001052"
     CDS             2452..3150
                     /locus_tag="ACL73E_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0801035.1"
                     /translation="MLPAYMKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3193..4089)
                     /locus_tag="ACL73E_001053"
     CDS             complement(3193..4089)
                     /locus_tag="ACL73E_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGS0801036.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4098..5033)
                     /locus_tag="ACL73E_001054"
     CDS             complement(4098..5033)
                     /locus_tag="ACL73E_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGS0801037.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTASELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5030..5755)
                     /locus_tag="ACL73E_001055"
     CDS             complement(5030..5755)
                     /locus_tag="ACL73E_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGS0801038.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     SYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5839..6474)
                     /locus_tag="ACL73E_001056"
     CDS             complement(5839..6474)
                     /locus_tag="ACL73E_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGS0801039.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6476..7303)
                     /locus_tag="ACL73E_001057"
     CDS             complement(6476..7303)
                     /locus_tag="ACL73E_001057"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0801040.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7325..7661)
                     /locus_tag="ACL73E_001058"
                     /pseudo
     CDS             complement(7325..7661)
                     /locus_tag="ACL73E_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(7662..8378)
                     /locus_tag="ACL73E_001059"
     CDS             complement(7662..8378)
                     /locus_tag="ACL73E_001059"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGS0801041.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRVQAPLVIKEVNGIKVALLAYSYGFNGIEQYISKEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSEMVEKDGDKKLIIY"
     gene            8891..9502
                     /gene="def"
                     /locus_tag="ACL73E_001060"
     CDS             8891..9502
                     /gene="def"
                     /locus_tag="ACL73E_001060"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGS0801042.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9547..10275
                     /gene="rlmB"
                     /locus_tag="ACL73E_001061"
     CDS             9547..10275
                     /gene="rlmB"
                     /locus_tag="ACL73E_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGS0801043.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10314..11225)
                     /gene="trxB"
                     /locus_tag="ACL73E_001062"
     CDS             complement(10314..11225)
                     /gene="trxB"
                     /locus_tag="ACL73E_001062"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGS0801044.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11291..11515)
                     /locus_tag="ACL73E_001063"
     CDS             complement(11291..11515)
                     /locus_tag="ACL73E_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGS0801045.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11593..12336)
                     /locus_tag="ACL73E_001064"
     CDS             complement(11593..12336)
                     /locus_tag="ACL73E_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0801046.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12336..13136)
                     /locus_tag="ACL73E_001065"
     CDS             complement(12336..13136)
                     /locus_tag="ACL73E_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0801047.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13294..13650)
                     /locus_tag="ACL73E_001066"
     CDS             complement(13294..13650)
                     /locus_tag="ACL73E_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS0801048.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13663..14175)
                     /locus_tag="ACL73E_001067"
     CDS             complement(13663..14175)
                     /locus_tag="ACL73E_001067"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGS0801049.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNK"
     gene            complement(14175..14669)
                     /locus_tag="ACL73E_001068"
     CDS             complement(14175..14669)
                     /locus_tag="ACL73E_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS0801050.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14804..15250
                     /locus_tag="ACL73E_001069"
     CDS             14804..15250
                     /locus_tag="ACL73E_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGS0801051.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15247..15894
                     /locus_tag="ACL73E_001070"
     CDS             15247..15894
                     /locus_tag="ACL73E_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGS0801052.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15915..16496)
                     /gene="pdxT"
                     /locus_tag="ACL73E_001071"
     CDS             complement(15915..16496)
                     /gene="pdxT"
                     /locus_tag="ACL73E_001071"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGS0801053.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREGILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16497..17372)
                     /gene="pdxS"
                     /locus_tag="ACL73E_001072"
     CDS             complement(16497..17372)
                     /gene="pdxS"
                     /locus_tag="ACL73E_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGS0801054.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17524..18903)
                     /gene="nox"
                     /locus_tag="ACL73E_001073"
     CDS             complement(17524..18903)
                     /gene="nox"
                     /locus_tag="ACL73E_001073"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGS0801055.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19197..20120
                     /locus_tag="ACL73E_001074"
     CDS             19197..20120
                     /locus_tag="ACL73E_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGS0801056.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20180..20785
                     /locus_tag="ACL73E_001075"
     CDS             20180..20785
                     /locus_tag="ACL73E_001075"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS0801057.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20804..22048
                     /locus_tag="ACL73E_001076"
     CDS             20804..22048
                     /locus_tag="ACL73E_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGS0801058.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22165..22422)
                     /locus_tag="ACL73E_001077"
     CDS             complement(22165..22422)
                     /locus_tag="ACL73E_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGS0801059.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22464..24500)
                     /gene="glyS"
                     /locus_tag="ACL73E_001078"
     CDS             complement(22464..24500)
                     /gene="glyS"
                     /locus_tag="ACL73E_001078"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGS0801060.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24712..25629)
                     /gene="glyQ"
                     /locus_tag="ACL73E_001079"
     CDS             complement(24712..25629)
                     /gene="glyQ"
                     /locus_tag="ACL73E_001079"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGS0801061.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(25824..26585)
                     /locus_tag="ACL73E_001080"
     CDS             complement(25824..26585)
                     /locus_tag="ACL73E_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGS0801062.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDLNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26858..27700)
                     /locus_tag="ACL73E_001081"
     CDS             complement(26858..27700)
                     /locus_tag="ACL73E_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGS0801063.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSITISRIQANLDCFGIELSHKERETLKTIAVQLGAPRVD
                     DVDF"
     gene            complement(27814..29205)
                     /gene="pgdA"
                     /locus_tag="ACL73E_001082"
     CDS             complement(27814..29205)
                     /gene="pgdA"
                     /locus_tag="ACL73E_001082"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGS0801064.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29443..29811)
                     /locus_tag="ACL73E_001083"
                     /pseudo
     CDS             complement(29443..29811)
                     /locus_tag="ACL73E_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            30032..31009
                     /locus_tag="ACL73E_001084"
     CDS             30032..31009
                     /locus_tag="ACL73E_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS0801065.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            31006..32088
                     /locus_tag="ACL73E_001085"
     CDS             31006..32088
                     /locus_tag="ACL73E_001085"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGS0801066.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(32152..>32557)
                     /locus_tag="ACL73E_001086"
     CDS             complement(32152..>32557)
                     /locus_tag="ACL73E_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGS0801067.1"
                     /translation="RYCYGAVDAHTGESFFLIAGRCNTEWMNAFLEELSQAYPDDYFL
                     LVMDNAIWHKSSILKIPTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRILEDV
                     MNQLQDVIQGLEKEVIKSIVNRRWTRMLFESR"
BASE COUNT         9663 a         7307 c         5835 g         9752 t
ORIGIN      
        1 tgttcaggtg cgagagcttt gacatccttt tctgtactta gccaagtcag ttttccgttc
       61 tcaaagcgtt tatataatat ccaaaatcct tgaccatccc agtaaaggac tttaaagcgg
      121 tctttacgtc caccacaaaa gagaaagact tgatcggaga aaggatccaa ttcaaagtgg
      181 gttttaacca gataagccag tgaatcgatt ccttgtctca tatccgtttt cccacatacg
      241 agatagacct gccctaggct agatagatga attgtcatag agcaacacct tatccaaaag
      301 ctgttctatc atttcgagat tgagagattg aaaaaaactt acttcaagct tgccaatacg
      361 aattttaagc agaatatcat ttctcttttt agaatcaaaa ggacgagatt gtggaatctc
      421 tacaggaaca ataggttgtg gcattaaaat atcctccaat agttttactt tactaatagt
      481 atacaggagg agctccatga atgatagata ccttgttatg acgcgcttac tatattagaa
      541 agttggctct ctaattaaat taattctcat tatatatatc aaaagaccgc agtttgaaaa
      601 ctacggtcta attttttgtc caaatgtaaa ccacttggaa ctattattca atttattctt
      661 tttagcaaat gttcccgttt taatcccagt tacagttttt aatcctctgt aaccgttgat
      721 tttacaaagc ttttaatttt tttgcgatta ttcccactca actgttgcag gtggtttact
      781 tgtaatatcg tagacgatac ggttaacatg atccacttca tttacgatac gtactgagat
      841 tttttgaagt acttcccatg gaattttggc aaaatcagca gtcataccat cgatagaagt
      901 gatagcacgg attgcaatcg tgtagtcata cgtacgaccg tcacccataa caccgactga
      961 acgaacgcct gtgttaacag tgaagtattg ccaaatatcg cggtcaagtc cagctttagc
     1021 gatttcttca cgaagaatag cgtctgattc acgaacggtt tcaagtttct cttcagtgat
     1081 ttcacccatg acacggatag caagtcctgg tcctgggaat ggttggcgcc atacgatatg
     1141 gtctggcata ccaagctctg taccaagagc acgaacttca tccttgtaaa gagtattgag
     1201 tggttcaatc aattcaaact gcatatcttc tggaagacca cccacgttgt ggtgtgactt
     1261 gatagtttga gctgtatccg taccagactc gataacatct gtatataaag taccttgagc
     1321 aaggaatttc acatctttga gcttgcttgc ttcgtcatcg aatacataga caaactcgtt
     1381 accgatgatt ttacgttttt gttcaggatc agaaacgcca gcaagtttgt caaggaaacg
     1441 tttagcagcg tctgctttga cgatattcaa accaaactta ccaccgagca tgtccataac
     1501 ttgatcagct tcgcctttac gaagaagacc gtggtctacg aagatacaga tcaattgatc
     1561 gccaatcgct ttttggagaa gaaccccaac gacagatgag tcaacaccac ctgatagacc
     1621 aagaaggaca cgtttatcac cgacggtttc acgaattttt ttgatctgca tgtcaatgaa
     1681 attatccatt gaccagtcac ctttagcctt acaaatgtta agggcaaagt tacgaaggat
     1741 atcatttccg tatacagaat gacgaacttc tgggtggaat tggataccgt aaatgtgttt
     1801 atctgggttt tcgatggctg cgtatgggca gtcagctgat gtacctgtac gaacaaagtc
     1861 agcaggaatc tcagtaaccg catcaccatg gctcatcaaa acagtctgtt catcaggtgt
     1921 tgattcaaaa agcgctgatg gtgtgtgagt tagggttgat tgaccgtatt cacgatttcc
     1981 agcatcacct gcaggaacaa cttttcctcc aagtttatgg gtcaataact gcataccata
     2041 acagattccc aaaattggaa ttccgagttc gaagatttct gggtcaatat caaatgaacc
     2101 atcttcatat acagaatttg gaccacctga tagaataatt cctacaggat tgacttcacg
     2161 aacttcagca gctgaaattt tatggctttt tagttctgaa aaaacaccaa tctcacggat
     2221 acggcgtgaa atcagctggt tgtactggct accatagtcc aatacgatga ttttttctac
     2281 atcttgcaaa tcagttgaaa tgttgctcat ctttttcctt tctcaaaaga aatatctttt
     2341 cccaatattc tatcacaaat aagggcgaat taccaactaa acaaggcgaa gtttgacttt
     2401 ttctagttta ttggggtaca atagagaaaa gatagaaatg aagtgaaaaa tatgctacct
     2461 gcttatatga aaatccatga tcagataaaa aaggatattg acgagtaccg ttgggctatt
     2521 ggtgagaggc ttcccagtga aagagatcta gctgagcagt ttgcggtcag tcgcatgacc
     2581 ctccgccaag ccgtatctct attagtcgaa gaaggcgtct tagagcgccg tgtaggaagc
     2641 ggcacctttg tttccagtac tcgagtacaa gaaaagatgc gagggacaac cagttttact
     2701 gaaattgtca aatcccaagg taaagttccc tctagccagc tcatttccta caaaaaaacc
     2761 attcccaatg agcaagaagt tgccaagcta ggaatttttc caacggacaa tattatccga
     2821 atggagcggg tccgctatgc cgaccaagtt cccctagttt atgaagttgc ttctattcct
     2881 gaaaaattca ttaaggactt taaaaaagaa gaaatcacca gtcatttctt ccaaaccttg
     2941 caaaaacatg gctatcgtat cggcaaatct caacagacca tctatgctcg ccttgctaaa
     3001 gaaaagattg cccactattt ggaagttgaa aaaggacatg ctattcttgg attgacccag
     3061 gtttcctacc tagaagatgg tactgctttt gaatacgtaa aaagtcaata tgtaggcgaa
     3121 cgctttgaat tttatcttga aaataattag attaccacgc aaaaactctc tgtcacgaac
     3181 aaagagtctt ttttattttt ctaagaataa atctttcaaa gaaatcaaag ttacagcaaa
     3241 caatatcatt gccataccaa gaaaatcaat gggataaaat tgttcattca ttattaagaa
     3301 ggcaaagaaa atcgccgata ttggctcaat tgaagccaac aagcttgact tgaccggtcc
     3361 tatcagactg gctcctttaa ggaaagctgt ataggcaaag acagtcccga taaggataat
     3421 gcctgcaaac gcaaggagaa aatcaagact agtcgggata tcggcctgta gaacccctgt
     3481 aaaaggaagg gcgaccaaac ctgctatgac cattcccaca ccaatgacca agctgctccc
     3541 ccacttttta atcaaggcta tgggtaaaat gatatacaga gcataagtca aggcagaaaa
     3601 gagaccccag aacagaccag caggtgtcat ggataactgg tccaactgcc catgtgttgc
     3661 gatcaggaag gttcctccga tggcgaatat gatggaaact atctctccca gtgtcggtgc
     3721 caccctatcc ttgatacagc tataaattaa aattccgaca ggacaaacat actgaagcac
     3781 cgtcgctgtt cccgcattgg tctcctgaat agcagacaga taggcgaatt ggttgagaaa
     3841 aagaccaatc agagcaaaaa taagaagaga cagcaaactc tttctatcct ttaaaaagac
     3901 cagtatttta tcctttgcag tagcataagc caagagcatg agaattccac cagcgattaa
     3961 aagacgcaag ttagtcaaga ccagagccga aattccgtgt gccattaggt attggccact
     4021 cgttcctgac aacccccaag caataccagc cacaactgtt agtaaagtcc cttttaaact
     4081 atttgacatg tctctcctta ctcttctttg cgaatcaagt tcatcacttg attgcggtct
     4141 aatatccatt gagctctctc gtccttttca taggtacgat tcgataggaa aatagtggct
     4201 tcttgcttct gacgattcca catgataaag gtacctgtat agcccgtatg gtctagccaa
     4261 tctccttcca aattccatgc taaagaacgt tccttgtcat ccaaaggaga aaaattttga
     4321 tttaagtctc ttgcaaaatc atctgctaaa tagtgttcta aaaagatttg taaatccttt
     4381 atagtcgaaa ataaaccagc actcccagca tgtctaccca ggagacgagc cttgggatca
     4441 tgcactatgc ctgcctctac acctctaact gttggaacag caagctcaac tggcccaaac
     4501 ttggtttccg tcattcccca aggtttccag acttgatcct ttaaaatcac atccaaatct
     4561 tgattaaaaa ttctttccaa aataaagccc aacagcaaaa aatggacatc cgaataaaga
     4621 aaggctggct gacttcgtct gttgagatga aacatcgctt cctttaattc agaggctgtt
     4681 aaaagatcac gattaggaat aaaaggatca aggtctgttg catgagtcaa gagctggcga
     4741 atagtgatgt ctggataatc actctcaggt aaaaaatcta ttaccagtct atcaatatct
     4801 aattgaccta tttcccacaa gaaggtacaa actgtgccaa ccccaacaac cttgctgaca
     4861 ctagctaggt cataaactag tcctgcctca gtctgcaagc catgctctgg ggcactctgg
     4921 cctaaataga actctgtcca ttgattgtcc ttaaaatacg caaaagaggc tccgggataa
     4981 attcctgcct cgatttgttc ttctattttt ttaataatct tggtccactt catacttctt
     5041 caaaccacaa ttcaacatta tttctatctt taccaaggaa gaatttttca gacttaggaa
     5101 taaaatattc agtagactca aacttctggc gaagacttgc tatgtctaat tcattgacca
     5161 agaacttgag catagataag tcccaggtaa ccgtattgtc cacagtcaaa tcctgcccct
     5221 gagctggaat aaaatcaagg gatgccccaa tttcagatga ttccaagaaa ctttcgatat
     5281 cagttgggag atgtaattcc atagaaatct caaatttact taaagaaatt gatgccaaat
     5341 ctgtttgaaa ttcaggcttt tctcctactt ctactagact tgctatgtca tcttccgcat
     5401 gaatcaaaat caaatcatct tctggtgaga aaatttcaaa agcgtagcta ttttgacctt
     5461 tatataatcg atgaatcgaa tctgttttag ataagattcc ttcaatttct aagggatttt
     5521 ccaccttgac aatcaatcta gctagttttt ttcttccctc taccttacga gtacgcatac
     5581 tgggagcttc ttctaaaacc agcttttcaa gacccgtttg gtcacctagt gacagaaagg
     5641 ccgattcttc taacaaggcc ttcattccaa gggtttcaat ataaaatgtt tcatttaatt
     5701 ttctattatt agcttttaaa gtaggaataa tccgtacaat ctgatttaca ttcataaatt
     5761 cctccgtcac tttttatttt aaaggatttt agaatttttt acaagatatt atgctcaaat
     5821 ttaacattat ttagctattt agtaaagata gtctttcaag gcttttgaca aagcctgata
     5881 accagcaata ctgaggtgca gtccatcagt tgtatattct tttttgagtt ggcctgcttg
     5941 gtctgtcaaa caatcaaata ctggcacaaa ttccacctgc atataggcag atgcaagctc
     6001 ttgataggct tgattccagt tctgaatttt ttcattcgag cggatataga ctgcctgctg
     6061 gtactcctct ctctcattga caggcaaaat ggaaagcaat ttaatctctg tcaatggata
     6121 atcgcgagca acggattgaa tgatagcttc gagattattg agagcctcat tcacaggaac
     6181 atcctttccg atatcatttg tcccaatcag aagaaaaatt ttatctactg ctccaccata
     6241 tagatgagca tcaaggttct ctagtaacag tcctgtctga tagccacgaa ttcctcgatt
     6301 gacaatcgtc tttgaagtcc caaatagctc ctgtagagga taatactcga caatggaatc
     6361 cccaataaaa agaatgtttg gttctacaac agaaatgtga tttaggtgac gatacttagt
     6421 ttgaattttt tcttgttcct ttaggagcca attttctaat aactgtactg ccacttcatt
     6481 ctcctttttc taaccagttt tccaaaactt gataaactcc tccttggctg ttggctggtg
     6541 ctagagcagt cgccacagct ttggctttct catcagcatt ttccatcgca taggcaattc
     6601 cagccatttc aagcatttca acatcatttt cactatcacc aaaagccatg atttcttggg
     6661 atttcaagtc ccagcgcttg agtaattcct ccaagcccca tgctttatga atcccagctt
     6721 ggaggatatc aatgcaacca tagccactgg atacagctcg gacacggcca tcaaagagag
     6781 cattgatttc ttccaaaacc gaactcaaac gttcctcacc aacaaccatg ctcatcttga
     6841 gcacaccacc aaagaggtca gatgttaatt catccacaaa ttgcatccgt tggtagaatt
     6901 tttcaatcat ttctggagtc ataaaacttt caagatctgt aaaaatcgta ccttccttga
     6961 caaaatcacc cttcatcccc gttacaacaa actggtcctg acacgctcga cccttgaaat
     7021 gagccaaagc cttgttgaca atggcgtcat cccatgtctg agcctgaatc aattcattgt
     7081 tttcaaaaat acgagcgcca ttagcaacaa ccagaaccac tcgatccacc aagggactca
     7141 gtagttgtct catgcggtga atttcattgc ccgtcgcaat gacaaaacga atgccccttt
     7201 gatccaactg atctaaaatc ttttccaatc gtgggagatc aagctgaccc ctagcatcca
     7261 gcaaggtccc atccatatct gtcgcaatta ccttaatcat catttacttt cctctggatt
     7321 caagctaata ccacttcaat cccacatgtt cattcatttc tttataggct gtatcaattc
     7381 gttccttagt cgcttcatct aactggtcac gatgactgcc acccctctat aaaatcttcc
     7441 aaaatataag tttggtaatg atacaaggga tatccttctg gtgaaaaggt tccctttggt
     7501 gttcgattga cccaagtagg atgagcttta gctgttccga tagttgtttt tccatccttc
     7561 ttcttgatgg tgacatccat gagaacacca cgttcagtcc acttagcatt ctcttcatct
     7621 cccatagatt caattcgttg attggaaatg aagttcccca tttaatagat aatgagtttc
     7681 ttatctccat ctttttcaac catttcagat ggttcaacaa cgtgaggatg ccctccaaag
     7741 ataatatccg ctccccaatc gatcatcttg tgataaagag ctttttgttc ttcagttggt
     7801 tccaatcgat actcaacacc catctgaagc atgataatgg tgatatctgc ttccttctct
     7861 gcccgttcaa tttcagcctt catcttatct tcgtttaaat ctgaaagata acgattatag
     7921 tcttccttag aaatatactg ctcaattcca ttgaaaccat aggaataggc taacaatgca
     7981 accttgatac cattcacttc cttaatgacc agcggagcct gaacacgtgg ttcgtgcgta
     8041 taaactccga ttggagtgat tccagctttc tcaataatat cggccgttga aataactccc
     8101 tcaatttgcg aatccaaaat atgattatga gctaaatcca gcacatgata acctgcctcc
     8161 ttaatagcat ccataacttc aacaggagca ttaaagagaa gataacccgc taaataatga
     8221 tccttattaa tggttccttc aaaatcacca atagctaaat ctgcttgctt gagccaagga
     8281 gtcacatact caaaattttc atgaaagtca taggtaccgt cttctttttt agctgaaaag
     8341 aaaagtccat cgtggtagag caaatccccg tgggccataa ttctggcagt tttttcctct
     8401 tcctactcct gagacttttg cttagtcccc tcttgagaaa tagtatctcg tttttgacta
     8461 gtcaagggat tccttggaag ctttcaaaca acaagaccaa gcccattgat aaaccaactg
     8521 ctagcaagag tatcgccaca aatcccttat tgctccactt gcgataactc ctaaaaagtt
     8581 taccaagccc ttcataaaac gaaaagctaa accaccctga tttcgatttt gtcttctttg
     8641 tatcttcgtt ctccctactt tcttatgcaa gccttttctt tttattatat cacagataag
     8701 tatttctttc acaattgaat tgaacttcct atctattttc tataaatcct aaatgccata
     8761 atgctttcaa ttcttgtcat tttgtgatat catgtagagg aaatgaacta atccacagtg
     8821 gcttattcca agtataccac ttgggctttg gcagtagcta actgcactaa acataatata
     8881 aggagagaaa atgtctgcaa tagaacgtat tacaaaagct gctcacttaa ttgatatgaa
     8941 cgatattatc cgtgaaggga atcctactct acgcacggtt gctgaggaag tcactttccc
     9001 cctatctgac caggaaatca tcctaggcga aaagatgatg caattcctta aacattccca
     9061 agatcctgtc atggctgaaa aaatgggact ccgcggtggt gttggactgg ctgctcccca
     9121 gttagatatc tcaaaacgca ttatcgctgt tttggtacct aatattgttg aagaaggcga
     9181 aactccacag gaagcctacg atttggaagc cattatgtac aatccaaaaa tcgtctctca
     9241 ctctgttcaa gatgctgctc ttggcgaagg agaaggttgc ctgtctgttg accgtaacgt
     9301 gcctggctat gttgttcgcc atgcccgcgt tactgttgac tactttgaca aagatggaga
     9361 aaaacaccgt atcaaactca aaggctacaa ctccattgtt gttcagcatg aaattgacca
     9421 cattaacggt atcatgtttt acgatcgcat caatgaaaaa gacccatttg cagttaaaga
     9481 tggtttactg attcttgaat aaagaaaatc ccgttgcaag acggggtttt gtgttataat
     9541 agaggcatga aaacaaatga tattgtctat ggtgtccacg ccgttaccga agccctcctt
     9601 gcaaatacag gaaacaaact ctacctccaa gaagatctcc gaggtaagaa tgttgagaaa
     9661 gtcaaggaac tagctacaga aaagaaggtg tccatttctt ggacatcaaa aaaatctctc
     9721 tctgagatga ctgaaggtgc tgttcatcaa ggttttgttc tacgagtgtc tgaatttgcc
     9781 tatagcgagc tagattacat ccttgcaaaa acacgccaag aagaaaatcc acttctattg
     9841 attctagatg gtctaactga tccccataat ctgggttcta tcttgcgaac agccgatgcg
     9901 accaatgttt caggtgtcat cattcccaag caccgtgctg tcggagtaac tcctgtcgtt
     9961 gccaaaacag ccacaggtgc tattgaacac gttccaattg cccgagtgac aaacctcagt
    10021 caaaccttag ataaactcaa ggatgaaggc ttctggacct ttggaacgga tatgaacggt
    10081 actccttgcc acaagtggaa tacaaaaggg aaaatcgccc tcatcatcgg aaatgaagga
    10141 aaaggcatct ctagcaacat caaaaaacag gtcgatgaaa tgattaccat tccgatgaat
    10201 ggacatgttc aaagcctcaa tgccagtgtt gctgcagcca ttctcatgta cgaagttttc
    10261 cgaaatagac tataaaaaag tttccagtca tctgattgga aactttttta tgattaacta
    10321 tgttctgtga taaacttgta ggcttcttga ccagcgatag ctccatctcc aactgctgtt
    10381 gttacttggc gaaggtcttt caagcgaaca tctccaactg caaagatacc gtcgactgca
    10441 gttttcatgt ggttatctgt cacaatccat cctgcctgat cttggatatt caattcttta
    10501 acaaaatcgc taagagggtc caatccaaca tagataaaga caccaccgaa ggcttgttct
    10561 gtcacttgac ctgttttcac attttcaaat acgactgatt ctactcggtt ttcacccttg
    10621 attttcctta ctacagaatc ccatataaag ctgattttct cattggcaaa ggcgcgatct
    10681 tgtaaaacct tttgggcacg aagttggtca cgacggtgaa caatggtaac agtcttagca
    10741 aaacgagtca agaagagggc ttcttcaaca gctgaatctc caccaccaac taccaataaa
    10801 tcttggtcac ggaagaaagc accatcacac acagcacagt aagaaacacc acgactgttc
    10861 agttcttctt ctccaggcac tcccaaagga cggtgtttag aaccagttgc tacgataact
    10921 gtacgtgttt catatgtttg gtcatcagtc atcactttct taaaatcacc atggtcttcg
    10981 acattttcaa cataaccata aatgtgctcc acaccaagat tttcaagtgg ttcaaacatc
    11041 ttttcagcca attcaggtcc actaatatta gcgtatcctg ggtaattttc gatatcagat
    11101 gtattattca tctgaccacc tggcagacca ccttcaatca aagctacttt tagattgctt
    11161 cgagcagcat acaaggccgc agtcatccct gcaggtccag caccgataat aatagtatcg
    11221 tacatataga ttccttcttt cttgttgtaa ctatctttat tctaactctt tcttgtcaat
    11281 cacgcaagga ttatgccttg aaaacaagaa ttaaactcat aaccgcaaag gataatactg
    11341 ggacaaccaa gactccaatc ataatcatat catagagatg ggcttggcga gccttggctg
    11401 tcttatcaac tcccgacatg gctctcagac caatccaaat ccctaaaaaa atcagaacaa
    11461 ggatggtggt caatatcaaa ctctcgaaat ataaagaaaa tagttgcagt agcatgattt
    11521 ctctcatttc tatctttttt aaagagtaaa ctcagctagt ccaactaact gagttttcct
    11581 ttatctatta tatcaaatat aagtccgttt gtaactagcg aagaattctt ttgtccgctc
    11641 ttctttaggg gtgtggataa tctcatccgg agttccagac tcgatgattt tccccttatc
    11701 taagaagaga atcttatccg caacttgagc tacaaaggac atgtcatgac tgaccaaaat
    11761 catggtctga cctgacttag cagcatctgc aatagacttt tctacttcac cgaccaattc
    11821 tgggtcaagg gctgaagttg gttcgtctaa gagcaaaaca tctggtttca tagcaagcgc
    11881 acgcgctagg gcaacccgtt gcttctgtcc acctgataaa tggcgaggat aatggttttc
    11941 acggtccgaa agcccaacct tagccaactc ttccttggca atcttagtcg cttcttggtc
    12001 agataatttc ttgacaacaa ccaagccttc tttcacatta tcaagtgctg ttcggcgttc
    12061 aaacaaatta aactgttgga aaaccataga caacttacgg cgtagggcaa ggatttcttc
    12121 ttgagtaatt ttagaaaaat caactgaaaa accatcaatc tgaatagagc cactgtcagg
    12181 tgtttcaaga taattgagac tgcgaagaaa ggttgatttt ccagctcctg aagaaccaat
    12241 caaggctaca acttcccctt tttgaatatc caagtccaga tgatccaaga cagtctgtcc
    12301 tgaaaaggat ttgcttaaat tcgaaatctt aatcattaac gaaggtctcc tttcacatct
    12361 gtttgcactg tatcaggtgc agaaatagcc atttttctct cgatgaaacg accgaggctt
    12421 tcaattccga tattgactac ccaataaaca agggcaacgg agatgaagcg ttcaaaatag
    12481 cgataatcag ctccacctag aatctgagct tgggcaaaga cttccacaac acccgcacta
    12541 aaagctagag atgttccctt ggtcaaaccg atgagggaat taatcaaggt tggagtagct
    12601 accaccgctg cattaggaat aatcactcgt cgataaactt gcgctcgggt catacccaga
    12661 ctgcgtgccg cctcaatctc accaggatta actgagagaa tggctgcacg aatggtttca
    12721 ctagcataag ctgcctcatt aaaggcaaag gcgacaatcg caaaagctgc agctggaatc
    12781 gcattgatat tgagaccagt tccccattgc tgattgaggg ctttcaaagc caaagggatt
    12841 ccgtagtagg tcaacatgag ttgcaccaaa atcggtgtcc cttttaagaa actaacaaag
    12901 aaggcctgca agggatataa aatcttgaca cgattgatct tcacaatggc aaaaagaagc
    12961 gccaaaacca agccaaaaag ggcaccacca attgtcaaca taattgttgt tggaagttgt
    13021 tggacaattc tagggattcc atcaaagacc gaacgtaggc taaacagctt gccatccgga
    13081 atcaattgca tcaagttttg gtaccaatct gatgctaaaa tcgttgtaac attcataaaa
    13141 acatcctctt ctgataatga ttcattctac catgcttctg ccgtcaatga aattatttgc
    13201 tacggtcaga tacagacttt gtctacctac tagtttatca tactttgaaa cagggaagtt
    13261 atatatttta tctatcaaag agatagataa aaactatttc agtcccagtt cttcataaga
    13321 ttttcgataa ccgatttgct taacagttcc attttctact aaaatgggcc gttttaacaa
    13381 cataccgtca cttgctaaca actcagccgc ttcttggttt gacaaacttc ctaccttatc
    13441 ttttagccct aattcacggt atttgattcc actggtgttg aaaaattgct tcaattcaaa
    13501 tcctgaggtt tctagccaat tcaaaatgac ttcttggcta ggtgtttctt ccacgatatg
    13561 gacggcttta tagtccacac ctaattgatt taattcttgt tttgcttttt tacaagttga
    13621 acatttgggg tattcgataa attctaacat gtgcttctcc ttctatttgt ttctatcttt
    13681 aaaatctact ccttcatgct ccaagagcca agctttcttt tccactcctg cagcatagcc
    13741 tgtcagacgc ttgcctgctc ccaacacacg atgacaaggt actaggatag accaaggatt
    13801 gcgtcccact gctccaccaa ttgcttgagc agaagccact tgcaggtctt gagcaatttg
    13861 tccataggtc actgtctgac cataaggaat tccctgtaaa taggaccaaa ctctcttttc
    13921 aaaattcgtt ccaattggcg ccaagagcaa gttggataaa tcctgaggct cgcctttaaa
    13981 gtaatcatct aagcaagcaa taactgggtc taaaatagga tgactaacaa cttcttctat
    14041 cgtttcatct cctagtcccc tctcaaaatg cttctgctcc tgaacccaaa ttccatacaa
    14101 ataatggtca tcagctacaa gtgatagaat accaattggt gaggagtaga ggatttttac
    14161 atacttcttt tgcattattt ctttaatttt tgataggcca agcgttcgcc atctactggc
    14221 accttaccaa cttgtttaaa accaagtttt tcaaaaatat gttgcataac cttgttttca
    14281 gcatgcgtat ctgagcgaaa atcaagataa tcaaaacctt caatcaagcc ctctaagaag
    14341 gtttgagcaa ctccttttcc ctgcacatct gctgccacag caatacggtg aaagactaga
    14401 tactctgact ctccagcttg ccagtttccc tcataaatag cttcataggc ctcctctgga
    14461 ctcttggtca cagcagcata ggctagcagt tctccctctt ccaaggctac gtaggcttgc
    14521 cctgagatga tatcatcgat aataacatct gcatttggat agccattttg ccactggtta
    14581 ctaccagcat ctgctaaaca ttttttggca tcctctatca cctgcatgat ggcatctact
    14641 tcatttggaa aagctaaacg aatttccatc ttttttcctc atttctgact agtttctccc
    14701 atcatagcat aatttaagtc tttctacaag cagttaaaac ttgactttgt atttttgtta
    14761 ttttataatc tagttatcaa aactatataa aaaggagttg aaaatgaaaa ctaccttttc
    14821 ctacccaaaa tgggcagaaa ttccaaacat taacctctat ctggaccagg ttttgctcta
    14881 tgtcaatcag gtctgcgccc ctatctctcc taataaagac aaaggcctaa cagcatctat
    14941 ggtcaacaat tatgtgaaaa atggttacct gacaaagcct gacaaaaaaa aataccaacg
    15001 ccaacagatt gcccgtttga ttgctatcac aaccctcaag tctgtatttt ctattcaaga
    15061 aatagcccag acacttaata ctctacaaac tcaagcaagt tcagaccaac tctacgatgc
    15121 ttttgtggac tacatgaacc aaggaattga cccagctaac cctattatcc aaaccagctg
    15181 ccaaaccgtt aaactctatc atcaaactct agacttaatc gatcatactc aagaggaggt
    15241 aatccaatga acactagtct taaactcagc aaacaactca gttttggaga ggagattgct
    15301 aatagcgtga cccatgctgt gggtgcagtc atcatgctta tcttgctgcc tatttcatcc
    15361 atctatagtt atgaagcaca cggattttta tcctctatcg gcgtttccat tttcgtcatc
    15421 agtctctttc tcatgttcct atcatccacc atttatcact ctatggccta tggttcgacc
    15481 cacaaatatg ttttgcgaat cattgaccat tctatgattt acgttgccat tgccggctca
    15541 tacacgcccg ttgtcttgac cttgatgaat aactggtttg gctatctgat tattgtcatc
    15601 caatggggaa cgaccatctt tggtattctc tataaaatct ttgctaaaaa ggtcaatgag
    15661 aaatttagcc ttgctcttta cctgattatg ggctggttgg ttctggctat cattcctgcc
    15721 attatcagtc aaacgacacc cgttttctgg agtctcatgg taactggcgg actctgttat
    15781 acagttggag ctggatttta tgccaagaaa aaaccttatt tccacatgat ttggcatctc
    15841 tttatcctag ctgcgtccgc acttcaatac atcgctattg tttattacat gtaaaaaagt
    15901 tgagaaattc aatctcaact tttttcttta cacatattga taaagtactg gtgcaagcgc
    15961 acatcatcag tcaattctgg atgaaaagaa cttaccaaca tatttttttc ttgggctgca
    16021 acaatttgat tgttcactgt tgctagaatt tctacaccct caccaacact actgataatc
    16081 ggaccacgga taaaggtcat tggaatcttg ccaactccct tacattctgc ttccgtgtag
    16141 aaacttccta attggcgccc ataagcatta cgctcgacca ccatatccat agttcctaga
    16201 tgactctctt tctgagaagt gatttcctta gccagcaaaa ttaagcccgc acaggtccca
    16261 aacactggta agccagatag aatgccttct cggatgggaa gtagcatgtt ctggtcacgt
    16321 aagagcttgc ccatggttgt agactcacca ccaggcaaaa tcaaacccga caagtcactc
    16381 tgatcttgct gaaaatcatc tagatttctg agttctacac tctcgacacc taattgatct
    16441 agcacttttg catgttctgc aaaggcccct tgcaaggcca atattccgat tttcatctat
    16501 tttcctcgtt cagccatgag aatttggatt tcattttcat taataccaac catggcttct
    16561 cctaaatctt cagagatttg agctaggatt tgaggattac ggaagttagt cacagcctta
    16621 acaatggcac tcgctcgttt aacaggatct cctgacttga aaatacctga accgacaaag
    16681 accccctctg cccctaattg catcattaac gcagcatctg ctggcgttgc aacacctcca
    16741 gcagcgaaat ttacaactgg caattttcca tgttcatgaa catattggac caattctaca
    16801 gggacttgca aatccttggc agcaacataa agctcgtcct cacgtaagtt ttgaatgcgg
    16861 cgaatttcct gattcatcat acgcatatga cgaacagctt ggacgatatc ccctgtccct
    16921 ggttctcctt tggtacgaat catggaagca ccttcagcga tacgacgcaa ggcttcaccc
    16981 aaatccttag caccacagac aaaaggaact tggaattctt tcttgtccac atggaaacgg
    17041 tcatcagctg gagatagaac ttcactctcg tcgatataat caatttcaat agcctctaaa
    17101 atctgagctt caacaaaatg cccgattctg accttagcca ttactggaat actaaccgct
    17161 tcttggattt ccttaatcat ctttgggtcg ctcatgcggg aaactcctcc agctgcacga
    17221 atatcagccg gaattcgttc caaggccatc acagctgccg caccagcagc ttctgcgata
    17281 cgagcctgtt caggattctg cacatccata ataacaccac ccttgagcat ctgtgccaag
    17341 tttttattta gttcataacg attttcagtc atttgtttta tcctcatcat ttgtattggt
    17401 agctaccttt tcattttaag tcagaacaga atgaagcaca agataaaaaa actataattg
    17461 tatggggaca gattagctaa aaactatctg accttaactt aaggccagat agctcattca
    17521 tttttatttt tcagccgtaa gggcagccat tgtgatgtag ttgtatggtt tgttgaagtg
    17581 tggcaagaag aagaggtctg tcaatgccaa tttatcaatt gtcacatgct cttggatagc
    17641 aagtgagaac atgtggattc ccatgctaat tgcaatatca tgtgaaacca tttgggcacc
    17701 aagaatttca cggctatctt tgtcaaagac aatcttaatt gctacttcat ggttgtcatg
    17761 tttcatgaat tctggttttt gaagatcgtt aaagcctgtt tcagttgcgt tgtaaccagc
    17821 agctttcgct ttttcaagag tcaaaccagt tgaaaccatg tgaagaccgt agattgagat
    17881 accatttgaa ccttgaacac cgattccttc caattcatgt ccacaagcgt tgtaggcacc
    17941 aacgatacca gtgcgaacag catttgaagc aagagcgata tagcttgtat ctttacgagc
    18001 attgtcataa acagtcgcac agtcaccaac agcgtaaacg cctgggatag atgtttcttg
    18061 tttcttgtct acaaggaagg caccgttgcg gaagagttcg atcttaccat ctgcaagggc
    18121 tgtgtttgga cggaaaccaa ctgcaaggat aaccatatcc acgtcaaagc tttctttgtc
    18181 agtaatcaag cgttcaactt taccgtcacc ttcgattgct ttaacagttt gacctagagc
    18241 caagcggatg ttgtgatctt ccaagttctt cgccatcatt tgtgtgaagt ctttgtcata
    18301 gtaaccgttc aagacagtat caacgatatc aacaaggaca acttcttttc caagacgttc
    18361 aaaggcttca gcaagttcaa caccgatgta accaccacca acaacggcga tacggtcgag
    18421 gtgttggctc ttgtcagaaa gtttattgat aacttcttca gcattttggt acaatttcac
    18481 gaattgtacg ttttcaagag ttgctttaaa ttcgcggttt cctttaacaa tttcaacacc
    18541 ttcgattggt ggcaagattg gtgtagaacc tgtagcgaaa atcaattttt cgtatgattc
    18601 tttgtgctct tttccttcaa cttccgctgt aactactttg ttatcatagt cgattgaaag
    18661 aacaggtgag ttcatgtaaa ctttagcacc tttagcttcc aatttttctt tatcagaata
    18721 gaacaagcct tcagcaccgt caatttgttc accaatccaa agagccattc cacatcctag
    18781 gaaagagatg ttagagtttt ggtcaaatac aacaatttcg ttctcatttc caaaattatc
    18841 caacatggta ttgatacatg ctgtaccagc gtggttagca ccgactacaa cgattttact
    18901 cataaaaatt tcctgccttc attctaaatt taccttacta gtataccatt taccgttagc
    18961 gtttacaagg ggggtactat tatttcagca ttttttatca aaaataattc cccatttatc
    19021 ctgttttcaa gcctcatgaa ttttatgagc atatttcttg actttttcca aattttgttt
    19081 gtgaaaattc taactttatg gtattataat aacatgaaaa tgaaatgtaa gggcttcaat
    19141 ttagatgatt atttgatatt acaacttatt ttctataaga gaaaggagtt ggtagcttga
    19201 ctcttcgttc acattctgaa cggctaatgg ggactactat cactatttca ttagtggatg
    19261 agcaagccga tatctttctc caaaaatcct ttgacttgct caaagaactt gaataccgct
    19321 tcaacgccaa tagtcaagaa tctgagttga tggaaatcaa ttatcaagca ggaatagccc
    19381 ccgtcacggt tcatccagac ctgtttgagc tgatttcact tgggttagag catagcctag
    19441 cgctctctag ccacctcaat atcagcattg gtcccttaat tcaaacctgg cgtatcggtt
    19501 tttcagatgc caaggtcgcc cagcctcaag aaattgaatc ggtgctgcct ctaatcaatc
    19561 ctcatggtat cgagttagat tcttctactt ctactgtgtt tttaaaacag aaaggaatga
    19621 agatcgatct aggttgttta gccaaaggat acagtgcgga taaggttgcc caatttctta
    19681 ggaaagaggg ggtgacttct gccttgatca atctgggagg gaatatcctg accattggaa
    19741 aaaatcaggc aagaggggat aacccatggc aaatcgggat tcaagaccca gccaatccta
    19801 ggggaaatca tttaatgacc atccctgttg tcaataaatc tgtcgtgact tcaggcattt
    19861 atgaacgtca cctgaccgtc gatggacaag attaccatca catttttgac agtcaaacag
    19921 gatatcctgt tgaaacggaa ctagcgagtc taacaatcat ctctgataaa tcagtcgatg
    19981 gcgaaatctg gacgactcga ctctttggag aaagacctgc ttctatcctc tggcaagtcg
    20041 aaagtttgga gggcatcgaa gtcatcctca tcgataaaga aggccaccta agctgttctt
    20101 caggaattcc tactctatag agacaactgt ttcaatggaa ttttaaaatt gtattatgta
    20161 aaaagagaaa ggaaatctca tgttaaaact tattgctatt gttggaacaa attcaaaacg
    20221 ttctacaaac cgtcaattgc ttcaatacat gcaaaaacac tttgctgaca aagctgaaat
    20281 tgagcttgtt gaaatcaagg ccattcctgt cttcaacaaa ccagctgaca agcaagtacc
    20341 tgctgaaata ttggaaattg ctgctaaaat cgaagagaca gatggcgtta ttatcggtac
    20401 tcctgagtat gatcactcta ttccagctgt tttgatgagc gctcttgctt ggttgtctta
    20461 tggtatttac ccacttttga acaaaccaat catgattaca ggtgcttctt acggtacgct
    20521 tggttcatct cgtgcccaat tgcaacttcg tcaaatcttg aatgctcctg aaatcaaggc
    20581 aaatgttctt ccagatgaat tcttgctctc acactctctt caagcattta acccaagtgg
    20641 cgacttggtt gaccttgatg ttatcaagaa attggatgcc atctttgatg acttccgtat
    20701 ctttgtaaaa atcacagaaa aattacgtaa tgcacaagaa ttacttcgca aagatgctga
    20761 agactttgac tgggaaaatt tgtaagatag gagaccaaaa agaatgaaat ttgttggact
    20821 tgttggatca aactacgatc aatcatataa ccgtaagctc ttggaattta tccgtcgcta
    20881 cttcaaactc aaatttgaat tagaagttct tgaaattgac gaagttccaa tgtttaacca
    20941 agatgaaaaa tgggatgaaa gtttccaatt acgttattta tataacaaaa ttactcgtgc
    21001 agatggtgtt atcattgcta ctcctgagca taaccacact atctcagctt cactcaaatc
    21061 tgtacttgaa tggctttcat acgaagttca tccatttgaa aacaagcctg ttatgattgt
    21121 gggtgcatca tactatgacc aaggaacatc acgtgctcaa gttcaccttc gtaaaatcct
    21181 tgatgctcca ggtgttaatg cctacacgct tccaggtaac gaattccttc ttggtaaagc
    21241 taaggaagct tttgataaca acggaaatat caccaacgaa ggcactgtta aattccttga
    21301 aacttgctta gataactttg ttaaatacgt aggagtcgtt tcgaaattga aaaaaccaaa
    21361 accaatcgaa tcagaagact tggattgtgg aaaaccaatc gctacaacca tcacagaagt
    21421 tgaccctgac gatccagaat gggtagaaaa agttgcagca atcactggtg ctgtttctgg
    21481 tgatacctat gtcaaattgg accacggtat cctaacagtt aaccaaattg atatgttctt
    21541 gaaagctatg ccatttgaat tgacatacgc tgacgataac aaccaattcc tctactacaa
    21601 caacgctcac caagatccag acactatgtt cgctaaacgt gtaccacctc aatcaggtag
    21661 ccgtatgtcg actgttcatg gttctcttcc accagcacgt atgaagaacg tagagtgggt
    21721 tatcggaaca cttcgcaacg gaaaccaaga atacgtccgt acgatcgttc caggttctcc
    21781 tgcaggtgtt atcaacactc acaactacca agcaatgtac tatcctgatg gatcatacgc
    21841 tggtatcaat gaaatcgtct ttaacttcca accatggctt gactggtacc taaaagagac
    21901 tggtcaacgt ttggtgggtg gtagcggacc atttgctcct gctgccggag gtcatggaga
    21961 cgccgatgct acttctggcg cttctgattc aggggatgct ggaggccacg gtggtgacgc
    22021 agacgctaca gccggtgcaa gttactaatg atagttttta ggaaccatta tggttccttt
    22081 tttagcgaaa aaagactagc aaacacaaac tgctagtctc tttgttatcg tttcatctat
    22141 ctttgttaaa agaaagaata catattatga atttggatca tcaagactac ggccatgtaa
    22201 tcctttttca cgttgtactt ggcgtagttt ttctggtgta acatcgtttc cttcttcgtc
    22261 cacaattttg attccttcaa tgtggtgacg aacagcgcgg cgataacctt cgatgtactc
    22321 ctcacgtagt ttggcttgtt ccactttttc ttctggtgtt aagccttctg tttttttctt
    22381 tttagcaagc tcattgatac gagcaatttt tttcggatcc atttcttctc ctctgtaata
    22441 agataaagtc cgtttatcaa attttattta gtgttaattt ggttaaaaca agcaaactta
    22501 gctgctttct tggttagttg tgacaagatt gccaaacgat tttgacggac agcctgatct
    22561 tcagccatta ccatagtatt ttcaaagaaa gcatcaatga ctgggctaag cgcaaagagt
    22621 tgtttcaatt gctgacttgc aggtcctgat aaaacgagtg tttctactgc ttctgccaaa
    22681 gctttttctt ggtcattctc aaatagtgct gaatcaaccg tagcaacccc ttctgccttc
    22741 tcagccaggt taaaggcacg agaaagtgat tcaacagatg gtttaaaatc ttcttccttg
    22801 cttacttcta cgagagcact tgctgcttcc aacatatctg ccacaacaaa gtttgaacct
    22861 gcaagaactg cttctttgat atcttttgga gtagagccca tcatcttatc aacacgagcc
    22921 ttgataaagt ccataacctc tgctttattt tcataagtca aactgtcaaa tttcaatgca
    22981 taaaggctat caatcagctc atccatagca atgtgccaac caaaggcatc caagatacga
    23041 accacacctt gagttgcacg acgaagggca taagggtcat tagaacctga tggaatcaat
    23101 cctactgaga agaaactcaa aatcgtatcc aatttgtctg caatggctag aactgcgccg
    23161 accttgctct ctggaagttc tccttcagct gatgtaggca tgtagtgttc acgaatagca
    23221 gctgccaccg ctggagtttc accagcaaga agggtgtatt tttcacccat aattccttgg
    23281 agttcgtcaa attcaccaac catacctgtc aacaagtcaa acttgtaaat ggctgctgca
    23341 cgagcaaggt caactgtttc atccactgac aaaccagctt tttctgccaa aagtacagtg
    23401 atttgacccg tacgaatcat gtgttcacga agggaaccaa tcttctcatg gaaggtgaca
    23461 ttgtttaatt tttcaacaag atctgaaatc accaattttt ggtcttcacg ccagaagaat
    23521 tctccgtctt ccaagcgggc taccaagact ttttcatttc ctttgatgac atttttcaaa
    23581 cgctctgcgt ttccgttacg aacagaaatg aagtttggca agagttttcc atcttgatca
    23641 cgaacaacaa agtaacgctg gtgttccttc atagaagtca ccaagacttc ttctggaact
    23701 tcaaggtatt tagcatcaaa acttcccatg aaggcagttg ggtattcaac caaattcaag
    23761 acttcattca gcaaatccgc atcaatttcg atacgtacac catgttttgc ctcaatttcc
    23821 ttgatttggt caacaatcat ttgctcacgt tcacatggat ctgcgattac aaactgctta
    23881 cgaaggtctt cttcatagct caatgctgac tgaattttgg tttctttccc caagaaacga
    23941 tggccacggc tcacacgact tcccttgata tcaaggaaat ccaagtcaaa ctcttgctca
    24001 tccaagagaa cagttaaagt gtggacaggg cggatgtatt caaagctatt tccagcccag
    24061 tgcatgctga cagggaaagt caatgacttc aagacatcta caacaccagg aacaatggct
    24121 tcaactgctt gaccaacttc ttccttagtg acatagacat attcttcacc cttgatttca
    24181 cggaattcga tatcttcaac agtcaagcct tttccacgga caaatccttg agctgctttg
    24241 gtgaagtttc catcactatc caaggcaatt ttctttgctg gtcccttgaa atcttctgtc
    24301 aaatcagact gtttgtctga taaaccagtc acacgaacag ccaaacgacg tggtgttgag
    24361 aaggtttgaa tggcttcaaa agacaggcgg ttttccttga ggaaggctgc cattttttcg
    24421 cctagttgtt tttcacttgg tgtgacaaca taggctggta attcttcaag accgagttct
    24481 actaataagt tttttgtcat gttttttctc cgaaaagtat ctttttattt tccagtttgc
    24541 cttatgtgat tggcacgcaa gcaaccaact tcgttgtttc attgctaaaa ttggagccaa
    24601 aagtctccaa ttttgcctag tatccttagt ttcactaagg ataccttcat cactgcggca
    24661 actggctcag ggctcactct gttcgcccat tttcgtaatt tgtcactctc tttattctgc
    24721 gtcttctgct aaaagtttaa ctcgtgtttc ttcatccaaa agtgggtaac ctaggcgttt
    24781 gcgttctgca acaaaggttt tggctacaac acgggccaag ttacggatac gagcgatata
    24841 gcctgcacgc tctgttacag atacggcacc acgcgcgtca agcagattaa aggtatgtga
    24901 acatttgaga acatagtcat aggcagggtg taccaagcct tcttctaatg cacgaccagc
    24961 ttctttttca aacttatcaa agttttcaag caacatttct tggtccgaaa tttcaaatga
    25021 atattttgag tgctcatact caggctggat aaagatttct ccgtatttta caccatcagc
    25081 ccactcgata tcatagacag agtctacttc ttgaatgtaa gaagccaagc gctccaaacc
    25141 ataggtaact tccgcagtca cagggccagt tgccaatcca ccgacttgtt ggaaataagt
    25201 gaactgagtg atttccattc cgtcaagcca aacttcccaa ccaagaccag ctgaaccagt
    25261 tgatgggttt tcccagttgt cctcaacaaa acgaatatcg tgctccaaag gattgattcc
    25321 caatttttcc aaagactcaa ggtaaagttc ttggatattt gatggagaag gcttcatgac
    25381 cacctggaat tggtggtgtt ggtagagacg gttagggttt tccccataac gaccgtcagc
    25441 aggacgacgt gatggctcta cataagctgc attccatggc tcaggtccga tagcacgaag
    25501 gaaagtgtaa ggactcattg ttcccgcacc tttttcatta tcataagcct gcataagcat
    25561 acaaccttgg tcattccaaa attgttgcaa agtcaaaata atttcttgaa atgttaattt
    25621 cttagacatt gaatactcct taataaaaaa taattacttg cgacacgagt ctgcctcgtc
    25681 gatcatacga ggcaagacga gttagtactg cgtctagctc aggcactcta gtgctgagcg
    25741 tggggcagtc cgactgtaag gaggtttctg ccactgatgc agtgaaatgt taatttctca
    25801 gacattgaat actcctttag tttttatatt tctttttcaa ttaatttctg ctgaacaaac
    25861 caatctaaca agggaaaagt tttttctgta tttgcccata aatgataaga atcaaagacc
    25921 gcttgtacac tacctaaatt ttctaccaac ttatctactg tcaaaaagct gcgccagtat
    25981 tcataaaaaa tacttgcata gttcttatca taagtcgaag aaccaaaatc attcaatgaa
    26041 tgccaaccat acttcttctg aaaaagttct acgagagatt gattacaaat tttttccgct
    26101 tgaaattcct cttctgtcaa gaaatacttg cgactaatat attcaaccat cccctcttcg
    26161 aaccagatat aagagtcata accatcaaaa tcatctaaaa aatgctccga ccaatgagct
    26221 aactcatgtc ctacaatctg taagaggaaa ttttcagata aagaatgata gtggctttct
    26281 attgcttgag tttgctcaga acactcgtag tccatcaact gatacaaata caactctttc
    26341 caaacagcta aatcaggcgt cataaccatt cgtctattat ttgtataggc tggaacagca
    26401 ctttccctaa taatctgtgt agcagcatta agatctgacc aaataacggc ttgcggtaaa
    26461 tcacagactg caagttcatt ctttaaaaaa gattgataat ctttcaactt ttcagtattt
    26521 cttactacaa aatcacgaaa tgtagctagt tgactatcgt cttttacaag ataaaggttg
    26581 tccacggctc tcctttcttt cacacaatag actgaataag caaaagaacc acatctgaca
    26641 agcctaggtt gatttaacct aggggcgtca gaaacgcggt tccaccctaa tttattactt
    26701 cattgttttt gaaaatacta cagaaagcgc cagcccatta ttttgcccta cttggctccc
    26761 actgtcccaa gctcgcttga agaacgccat aagactttct ttcctgctga ctattatatc
    26821 aaaaattaga ataatgtaca attcttttta tgattttcta gaaatccaca tcatcaactc
    26881 gtggagcacc caattgaaca gcaatcgttt ttaaggtttc tctctcctta tgactcagtt
    26941 caattccaaa gcaatcaaga ttagcctgaa tacgagagat tgtgatagat tttggaagtg
    27001 gtaaaaatcc ttctgccaag ctccaggcca aggctatctg agcaaccgat tttccgtgat
    27061 ttgctgctat ttcttggact tgcttgctat caaacagttc tccttgtcca aaaggccccc
    27121 aagcttccaa taaaattccc ttttcacgac agtaagctac gacttgatct tgatacacac
    27181 ctggcgccaa gcgaacttga ttgaccgcag gaacgatagt tgcagtttca agcaaggcat
    27241 ccaaatgatg gggaagaaaa ttgctaacgc cgatagcacg gattttccct tcttgataga
    27301 ggtcttccat cgctctccaa acttccgcat tgcgagtttt ccatgcgtca ttttctctga
    27361 gcggttttgg gttcggccaa tgaatcaaat acaaatccaa ataatccaag cccagttttt
    27421 ctatagattt ttccaaagct tgacgagttt gctcataggt ttgctgacta ttccaaagct
    27481 tggtagttac gaacatttct tcacgtggaa ctccgctatc tttgattgct tgaccaacac
    27541 tttcttcatt ctgataaatc gccgccgtat caatatgacg ataaccagcc ttcaaggctt
    27601 ctaacactgc acgataggct tcttctccat ccttagcctt aaaagttcca aatcccaata
    27661 ctggaatttc tactccatta tttaattgat aggtattcat atgcttctcc ttctatttta
    27721 ttcatcaatt atagcataaa acatttttta agtagtacta tcttctgtaa aaaataagtc
    27781 tgtcaaatat ctaacagacc tattttttct tgcttattca tcacgactat agtacagctc
    27841 atgagctttt aggcgagtat tgagcatctc tggtatggtc acaaaggtat aaccttgatt
    27901 tttcaaatac tcaatgaccc ttggcaaggc attgactgtc ggactgtgaa tatcatgcat
    27961 caaaacgata gagccgttag ctacttgatg ctgaatttct gtcaaaatag atgcttcatt
    28021 tttactcttc cagtccagac tatccacatc ccacatgata aagctcaaat ccaagctatt
    28081 gcgaatatca tctgtaatag caccataagg tggacgcatg agtttagaac tagaacccag
    28141 cactttagtt agcacatcct cagtatcagt aatctgcttt ttagcttcat caagagagag
    28201 ttgcgagaga atcggatggc tccaactatg gtttccaaca acatgacctt cagattttat
    28261 cctcttcacc aagtcctcat tcccagaaac atttttccca agcacaaaga aagtcgcttt
    28321 aatatcatat ttagctaggg tctctaatac ctgcggggtc gttgctggat ttggaccatc
    28381 atcaaaggtt agagcgacaa ctttttgatg tttcttatca aagtaagatt ggtacaaggc
    28441 cgcatctttt tcgagtaagt acgaagattg gataacatca aagaaagcag atactggcaa
    28501 ggctatctct tctaaatttt caaccacagg acttggataa aggataatct gactatcctt
    28561 gtaatcaaaa ttccatgcag acaagtcttg gtcagagaag ttttttacaa tctgctcact
    28621 ctggtcttgc tctatttttt tatcctctat gaaggaggtc aactctttta tcagctgttc
    28681 cttagcctta ctagcatctg aaaacagttg gtcaagtgta aaaggttgcc catcttctgt
    28741 taagtgaacc tttcctagac tggtcttttc agtctcttca atcttaaaag caactaaatc
    28801 atagatttgt ttggtcacat tacgattaac gactcccttt aaacctgact cttcttgctc
    28861 tgtatagtag aaaacaagat tgtccttact ttctagcttg tccttaacat cttgatttat
    28921 cagctcccta acagaggaaa tcactttctc cccttggaga ggataatagg caatcacttc
    28981 ggcttgcccc tgacgaaaat gctccttctg atttccctca ctcaattgat catctttctc
    29041 ttttttgagc gattcaatct tttgctcaaa acttttttgc tggtagatct taaaagcaat
    29101 aaatccgcct aataggcaaa tagaaattgc taaaatacca atcaaagcca ataatacatg
    29161 tctcgttttc ccgtgtctgc cacgtcctag tctactttta ttcatattta tatcataaca
    29221 aatttgagca ataatttcaa tgatacaatt tggcaatcca caattcctct agcaagccaa
    29281 agcatcttac atcaactcca acatccgtat ctgtagagat tatgtagttt tctatctatg
    29341 gaatttctag tagattgaag ctagaatagt agacctatac ttctaaaaca ttgttagaaa
    29401 tcgatttgac tgtcctgatc gatttgtcct gttctcattt catttcacta taaaactatg
    29461 aaaagctagg tcatctgaga agtaattact atcgacaatt gcgatagcgt atactagtgc
    29521 gatttgtttg tagctctggt gggtatcacc ttcacgttgg cgaatttttt ctaggttttg
    29581 attaacctga ctgcacagat aagcccatag gcgattgatg aaaaaattct gatgatgaac
    29641 ctgaatttcg atgataactt ggattccatt atctaactcc gccaagacgt ctatactagt
    29701 atagaaatct tgcgctgagt agggcatgga aggcaagacg tgaatgttac ttccctccaa
    29761 aatcgtcaca ttttttgctg gcaagtccag catatcgcgg ataaattgac aaatcattag
    29821 ttgggctgat acctggatgt ctgagaatcc tccttttcct ccttctatta tagcacattt
    29881 ttaaatctag gtttgctaga ttctatgctt ctatctattt attcggaaaa gaaagctaat
    29941 agcttatttg aaattttctc ctctctgttg gatagtcccg tctatctatg ttataatgaa
    30001 agaaggattt aaaatcggaa aaggagtatt tatgctaaaa ttaggtgtca tcggaactgg
    30061 cgctatcagc catcatttca tagaagcagc ccataccagt ggagaatacc aactggtcgc
    30121 aatctattct agaaaactag aaactgcagc aacctttgct tctcgctatc agaatatcca
    30181 actattcgat caattagaag tcttcttcaa atcttctttt gatttagtct atatcgccag
    30241 tccaaactcc ttacattttg ctcaggcaaa agctgccttg tctgctggta aacatgttat
    30301 tcttgaaaag ccagctgtca ctcaaccaca agaatggttt gatttgattc aaacagctga
    30361 aaaaaataac tgttttatct ttgaagcagc tcgtaattat cacgagaaag cctttactac
    30421 tatcaaaaac tttttagcag ataagcaagt gttaggagca gatttcaact atgccaaata
    30481 ctcttccaag atgcctgact tattggctgg acaaacacca aatgtctttt cagaccgttt
    30541 tgctggtgga gccctcatgg atttggggat ttatcccctc tatgctgctg ttcgtctttt
    30601 tgaaaaagct aatgacgcga cttaccatgc tcaacagctt gacaatagca ttgacctaaa
    30661 tggagatggt atcctcttct acccagacta tcaagttcac atcaaggctg gaaaaaacat
    30721 cacttccaat cttccttgcg agatttatac aacagatgga accttgactc tcaacacgat
    30781 tgagcatatt cgctcagcta tttttaccga ccaccaagga aatcaagtcc agcttcctat
    30841 ccaacaggct cctcatacga tgactgagga agtcgctgca tttgcacaca tgatccagca
    30901 accagatctg aatctctacc aaacttggct gtatgatgca ggctctgttc atgagctact
    30961 atataccatg cgccagactg ctggcgttag atttgaggca gaaaaatgaa aaccaaacta
    31021 ccgactgaat ggcaagaact gagtgaccaa ctcggtttcc aagaattcac ccccattcaa
    31081 actcaactat ttgagctcct tcttgctgga gaaaacctcc taggagtgag ccaaaccgga
    31141 actggtaaga ccctagcgta tctcctacca agtcttctca gactacaaaa gaaaaaagcc
    31201 caacaactct tgattctagc accaaacacg gaacttgctg gacagatttt tgatgtatgt
    31261 aaaacgtggg cagaagctat cggattgact gctcaactct tcctttcagg ttcaagtcag
    31321 aaacgacaaa ttgaacgtct taaaaagggg ccagaaattc tgattggaac tcctggccgt
    31381 atctttgaac tcattaaact taaaaaaatc aagatgatga atgtggaaac catcatcctg
    31441 gatgaatttg accaattact agatgattct cagattcact ttgtagagaa aatcactcac
    31501 tacgcacctc gtgaccacca actggtctac atgagtgcca cgaccaagtt tgaccaagaa
    31561 aagattgtgc cgaatacacg cactattgat ctctctgatc aaaaattgga caatatccag
    31621 catttctaca tgcaggtaga ccaacgtcat cgagtggata tgctacgaaa actggctcat
    31681 gtagaggatt tccgtggtct agtcttcttc aatagcctgt cagaccttgg gaatgccgag
    31741 gaaaaactac agtatcgtga tatattggct gtttccctcg ctagtgatgt taatgttaaa
    31801 tttagaaaaa tcatcttaga aaagtttaaa gataaccaac taaccctgct tcttgcaact
    31861 gaccttttgg ctcgtggaat tgatatcgat agcctagaat gtgtcgtaaa ctttgatatt
    31921 cctagagata gcgaaaccta cacacaccgt gctggccgta ctggtcgtat gggcaaggaa
    31981 ggttatgtta tcactctcgt cactcatcca gaagaaatca aaaaacttaa aaagtttgca
    32041 agtatccgag aaattgtcct aaaaaaccaa gaactctata tcaaataaag ccccattgct
    32101 ctatacacat ccagtgtatg gagctttttt ataagcaatt caattttata ctcatctgct
    32161 ttcaaaaagc attctagtcc atctccgatt aacgatggac tttatcacct ccttctccaa
    32221 tccttgtatg acatcttgaa gttgattcat gacatcttcc aaaattcgaa aggctttatt
    32281 cttaaatcca cgtttacgaa tctctttcca cacttgttca atggggttca tctctggtgt
    32341 gtatggagga ataaatgcaa aaccaatatt agtcggaatc tttaagatac ttgatttatg
    32401 ccatatagca ttgtccataa cgagtaaaaa ataatcatct ggataagctt gtgaaagctc
    32461 ttctaaaaag gcgttcatcc actcagtatt acatctacca gctattaaga aaaatgattc
    32521 gcctgtatgg gcatcaacag ctccataaca atagcga
//
LOCUS       DBERDS010000020        32315 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.020, whole genome shotgun sequence.
ACCESSION   DBERDS010000020 DBERDS010000000
VERSION     DBERDS010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32315
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.020"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            139..1128
                     /locus_tag="ACL73E_001087"
     CDS             139..1128
                     /locus_tag="ACL73E_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0801068.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            1156..1959
                     /locus_tag="ACL73E_001088"
     CDS             1156..1959
                     /locus_tag="ACL73E_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGS0801069.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            1983..2894
                     /locus_tag="ACL73E_001089"
     CDS             1983..2894
                     /locus_tag="ACL73E_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0801070.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2950..4284)
                     /gene="pepC"
                     /locus_tag="ACL73E_001090"
     CDS             complement(2950..4284)
                     /gene="pepC"
                     /locus_tag="ACL73E_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGS0801071.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(4501..5223)
                     /locus_tag="ACL73E_001091"
     CDS             complement(4501..5223)
                     /locus_tag="ACL73E_001091"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS0801072.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(5491..5721)
                     /locus_tag="ACL73E_001092"
     CDS             complement(5491..5721)
                     /locus_tag="ACL73E_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS0801073.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(5731..6972)
                     /locus_tag="ACL73E_001093"
     CDS             complement(5731..6972)
                     /locus_tag="ACL73E_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGS0801074.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(6994..7146)
                     /locus_tag="ACL73E_001094"
     CDS             complement(6994..7146)
                     /locus_tag="ACL73E_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801075.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(7167..7445)
                     /locus_tag="ACL73E_001095"
     CDS             complement(7167..7445)
                     /locus_tag="ACL73E_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGS0801076.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(7438..7701)
                     /locus_tag="ACL73E_001096"
     CDS             complement(7438..7701)
                     /locus_tag="ACL73E_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGS0801077.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(7803..12194)
                     /locus_tag="ACL73E_001097"
     CDS             complement(7803..12194)
                     /locus_tag="ACL73E_001097"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGS0801078.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(12298..14379)
                     /gene="fusA"
                     /locus_tag="ACL73E_001098"
     CDS             complement(12298..14379)
                     /gene="fusA"
                     /locus_tag="ACL73E_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGS0801079.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(14804..15274)
                     /gene="rpsG"
                     /locus_tag="ACL73E_001099"
     CDS             complement(14804..15274)
                     /gene="rpsG"
                     /locus_tag="ACL73E_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGS0801080.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(15294..15707)
                     /gene="rpsL"
                     /locus_tag="ACL73E_001100"
     CDS             complement(15294..15707)
                     /gene="rpsL"
                     /locus_tag="ACL73E_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGS0801081.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16124..19966
                     /gene="spuA"
                     /locus_tag="ACL73E_001101"
     CDS             16124..19966
                     /gene="spuA"
                     /locus_tag="ACL73E_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGS0801082.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            complement(20066..21115)
                     /locus_tag="ACL73E_001102"
     CDS             complement(20066..21115)
                     /locus_tag="ACL73E_001102"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGS0801083.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(21386..23194)
                     /gene="glmS"
                     /locus_tag="ACL73E_001103"
     CDS             complement(21386..23194)
                     /gene="glmS"
                     /locus_tag="ACL73E_001103"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGS0801084.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(23386..24765)
                     /gene="bglA"
                     /locus_tag="ACL73E_001104"
     CDS             complement(23386..24765)
                     /gene="bglA"
                     /locus_tag="ACL73E_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS0801085.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            complement(24865..26718)
                     /locus_tag="ACL73E_001105"
     CDS             complement(24865..26718)
                     /locus_tag="ACL73E_001105"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGS0801086.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(26731..27990)
                     /gene="rseP"
                     /locus_tag="ACL73E_001106"
     CDS             complement(26731..27990)
                     /gene="rseP"
                     /locus_tag="ACL73E_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGS0801087.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(28012..28815)
                     /locus_tag="ACL73E_001107"
     CDS             complement(28012..28815)
                     /locus_tag="ACL73E_001107"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGS0801088.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(28824..29582)
                     /locus_tag="ACL73E_001108"
     CDS             complement(28824..29582)
                     /locus_tag="ACL73E_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGS0801089.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(29813..30385)
                     /locus_tag="ACL73E_001109"
                     /pseudo
     CDS             complement(29813..30385)
                     /locus_tag="ACL73E_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            complement(30366..31364)
                     /gene="ruvB"
                     /locus_tag="ACL73E_001110"
     CDS             complement(30366..31364)
                     /gene="ruvB"
                     /locus_tag="ACL73E_001110"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGS0801090.1"
                     /translation="MSRILDNEMMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            31498..31590
                     /locus_tag="ACL73E_001111"
     CDS             31498..31590
                     /locus_tag="ACL73E_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGS0801091.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT         9362 a         7525 c         6232 g         9196 t
ORIGIN      
        1 acatatcaac atacaaaaat aaaaattttt taatttttta tgataaatag ttgctttttt
       61 tatgaaaacg gtttatactt aaacagtctt aaagttttct taaatgaaaa ctaaaacaaa
      121 aaaggaggaa tgacaataat gagtatcgga atcattattg cgagccacgg cgaatttgct
      181 gcgggtattc atcagtcagg atctatgatc tttggtgaac aagaaaaggt tcaagttgtg
      241 acctttatgc caaatgaagg tcctgatgat ctatacgcta agtttaataa cgctgttgct
      301 gcatttgacg cagaagatga ggttctagtt ttggctgacc tttggagtgg ttctccattt
      361 aaccaagcta gtcgcgtgat gggagaaaat cctgagcgta agtttgccat catcacagga
      421 cttaacttac cgatgttgat tcaagcctac acagagcgcc tcatggacgc tgctgcaggt
      481 gtagaaaaag tcgctgctaa tatcattaaa gaagccaaag atggcatcaa agctcttcca
      541 gaagagctaa atccagttga agaagttgca agcgctgcag ctgctccagt tgcccaaact
      601 gctatcccag aaggaactgt tatcggagac ggtaaattga aaatcaatct tgcccgtctt
      661 gacacacgtc tacttcacgg tcaggttgca actgcttgga ctccagattc aaaagcaaat
      721 cgtatcatcg ttgcttcaga taacgtggct aaagacgacc ttcgtaaaga attgattaaa
      781 caagcagctc caggtaatgt caaggctaac gtggttccaa ttcaaaaact gattgagatt
      841 tcaaaagacc cacgttttgg agaaacacat gcccttatct tgtttgaaac acctcaagat
      901 gcccttcgtg ccatcgaagg cggcgtgcca atcaagactc ttaacgttgg ttctatggct
      961 cactcaacag gtaaaacatt ggtcaatacc gttttgtcta tggacaaaga agatgttgct
     1021 acatttgaaa aaatgcgtga cttgggtgtt gaatttgatg tccgtaaagt accaaatgat
     1081 tctaaaaaag atttgtttga cttgattaac aaagccaatg tcaaataagc cattatttat
     1141 gaaaggattt taaacatgtc tattatttct atggttttag tagtcgttgt agccttcttt
     1201 gcaggtcttg aaggcatcct cgaccagttc caatttcacc aaccacttgt agcctgtacc
     1261 cttattgggc ttgtaacagg tcacttggaa gcagggatta tcctcggtgg atcgcttcaa
     1321 atgattgccc ttggttggtc aaatatcggt gctgctatcg ctcctgatgc tgcacttgct
     1381 tctgtcgctg ctgccattat catggttctt ggtggtgact ttaccaagac tggtatcggt
     1441 gttgcccaag cggttgctat ccctcttgcc gtagctggtc tattcttaac tatgattgtt
     1501 cgtacaattt cagttggatt ggttcacact gctgatgctg ccgctaaaaa aggtgacttc
     1561 ggcgctgtgg agcgtgctca tttcattgcg ctacttttcc aaggacttcg tatcgcgctt
     1621 cctgcagctc ttctccttat ggtaccaact gaaactgtac aaagtatcct tagtgccatg
     1681 ccagactggc tcaaagatgg tatggctatc ggtggtggta tggtcgttgc cgttggttac
     1741 gccatggtta tcaacatgat ggcaactcgt gaagtatggc cattcttcgc tcttggtttc
     1801 gttcttgctg ctgtgtcaga tattactcta atcggattcg gtgctatcgg tgttgctatc
     1861 gctcttatct accttcacct ttctaaaact ggtggaaatg gtggcggagg agccgcaact
     1921 tctaacgacc caatcggcga tatcctagaa gactactaag ataagaaagg actgaaaaca
     1981 tcatgactga aaaacttcaa ttaactaaat cagatcgtaa aaaagtttgg tggcgttcaa
     2041 ccttcttaca agggtcttgg aactttgaac ggatgcaaaa cttgggctgg gcttatacac
     2101 tcattccagc tatcaaaaaa ctctatacta aaaaagaaga tcaaatcgct gctcttgagc
     2161 gtcaccttga gttcttcaac actcatccat acgtagctgc tccagtcatg ggggttactc
     2221 ttgcgcttga agaagaacgt gctaacggtg tggaaatcga tgacgctgct atccaagggg
     2281 ttaaaatcgg tatgatggga cctcttgctg gtatcggtga cccagtattc tggtttacag
     2341 tacgcccaat ccttggatct ctcggtgctt cacttgccct tactggcaat atcttggggc
     2401 cactcctctt ctttgttgca tggaacttga ttcgtatgtc attcttgtgg tatgttcaag
     2461 agattggata caaggctgga tcagaaatca ctaaagatat gtctggtggt atccttcaag
     2521 atatcactaa aggagcttct atccttggga tgttcattct tgctgtcctt gttcaacgct
     2581 gggtaaatat taaatttgct ttcgatgttt ctaaagttca actagatgaa aaggcttata
     2641 tccattggga taaattgcca gaagggtcta aaggtatcca agaagcattc gcacaagtag
     2701 gacaaggatt gtctcaaact cctgaaaaag ttactacttt ccaacaaaac ttggatatgt
     2761 tgattcctgg attatcagga ctactcctta ctttactttg catgtactta cttaagaaaa
     2821 aagtatctcc aatcactatt atccttgccc tcttcgcagt gggtattgtg gcacatgttc
     2881 ttcacatcat gtaatcaagc aactaaaaag gaaccaggtt ctaaaatctg attccttttt
     2941 tctatgcttt tattcagcca aggctcccat tggatcccat ggtgcaagta cgattggttc
     3001 tgctccatag gcagcttgtt cttctgctgt cagcaattcc ttacgaacaa cgatttggta
     3061 tgtgtattcg tccatccaag cgtctgaggc aacaaagtaa ccatctgtac cgaccttgtc
     3121 tccccatgag ttttcaacct tccacttggt tgatttacca ttttcgtcca agtcaacacc
     3181 tgtcaagacc atggcgtggg tcatcaagct ttcgctatag tccaaacgtc cagccttgtc
     3241 ttgagtaagt ttaatgtcca tgcttgattc aaagtcataa acatctgtcg caaggatgcc
     3301 agccttacgg ttgctgagct ggccgacatc agaaccaaac caaacagtct cacctgcttg
     3361 catttgggca atcgccaatt ctttcaagcg ctccattgga acgttgatgt agcgaactgc
     3421 acggctacca accacattcc ccaacatctc aactgtgtaa gattttccgt aaggtttatc
     3481 agcagttgga gcattgataa cagaaacgta gtcttctaaa ggaagattga catatttctt
     3541 gtaaaactct tgtggtgtga ttcctttttc acttttatag ttgttatctt tatcgcgata
     3601 agcaaagtca aacttgcgtg gtggaagtcc taatgacata gcaagaaagt taaagatttc
     3661 ttgcaagagg tcttctttct tagcttgaac agtcgcttga tctgcaccag aaacaagcaa
     3721 atcacgcaag atttgagcat cttgacgaag caatttatta aggatcgcat ttagctcacg
     3781 actgctgcta gatgaaacag actcaggata aactgactta ggcacgacac cgtatttttc
     3841 aaagagggaa acgaccatat cccattgacc gccatcttgt tgaggtgttt ggagtaagaa
     3901 gctaaccttg cggctagtca attcttggtc tgaagtcgca atgacttgct ccaagaacca
     3961 gtttgatttc tcatacttat cccagaagaa agtgtgggct tgtgacaact caaagttctc
     4021 caatttgtat tgcgagatga gtttgtggcg gaaggtgttg agagccgcaa acatccagca
     4081 acgaccagac gctttctggt tagtgacctt gtccttggtt aaatccaatg agaaaacagg
     4141 tgtgttgtct acatggcttt ggcgacattc cagagctgca aaaattccgt tgtggctggc
     4201 agcattttca atcgcttggt attttacatt tgcttcatag ttggcaaata gtttatcagt
     4261 aaatgattct tgaatcgcgt tcatagattc ctccttttat tctacagtct attataactc
     4321 ttttcacaaa ggaagcaact aaaaaacata aaaggcgagg acattgtccc tcaccttttt
     4381 cgaatttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg ccgtactcaa
     4441 gtacagcctg cggctagttt cctagtttgc tctttgattt tcattgagta ttaaactaaa
     4501 ttaaataata ttagcgcgga gaatttctaa ttcttccttg gtcaagcgac gccattcccc
     4561 tcgttccagg ttctcatcta atactaaagt tcccatagtc aatcgttgca agtccaccac
     4621 ttccttgcca cagtagccca ccatacgctt gatctgatga aacttccctt ctgcaatggt
     4681 cacacggatt tggctctgat tcttttctgc atctgtggaa agaatctcca gtctagcggg
     4741 ctgacaggta aagtctttga gcggaatgcc cttgataaat gtctccacat cttcttgggt
     4801 cataattccc ttgacctgag cctgataagt cttgtccaca tgacgcttgg gcgaaagaag
     4861 aacatgagcc agctgaccat tattggtcaa gagcaaaaga ccatgcgtgt caatatccaa
     4921 gcgtcctact ggaaaaactt ccttactccg cgccaagtca tccaacaagt ccagaacggt
     4981 tctgtgcttg ggatcctcag tcgctgagat aactcctttg ggcttgttca tcatgtagta
     5041 gacaaactct tcatactcca acacttgccc atcaaagcga atctcatcta ttttttcatc
     5101 aatctgcaat ttagctgatt tttctttttt accatttaca gtcacgcgcc cagccttgag
     5161 caagtttttg acctcagtcc gacttcccac cgcacaggca actaaaaatt tatctaatct
     5221 catagaacta ttatatcata tcaaaaggag gctagtacaa tgaccaacct ccttttcgtt
     5281 tcatactctt caaaaatctc ttcaaaccgc gtcaacgtcg ccttgccgta tatatgttac
     5341 tgacttcgtc agttctatct gcaacctcaa aacagtgttt ttagctgact tcgtcagttc
     5401 tatctgcaac ctcaaagcag tgctttgagc aacctgcggc tagtttccta gtttgctctt
     5461 tgattttcat tgagtatcag atttaggaaa ttaacttcct cgtctccaaa aaatagctaa
     5521 aacaatcatg gctcctaaaa tcgctgggat aatagctgtt cctgataaaa ctggccccca
     5581 agttccaaag agcaagtgac ctagaaaggc tccgatccaa ccgagaaaca tttttccaaa
     5641 acatcccatt cgctctccac gattggtcat agcacctgct aaaaatccca ctaggagacc
     5701 aacgaacata cttcctaaca tattatctcc ttaatttgcc caattcccat tacggaaaag
     5761 aggtacccgc gttccatcct cacgaatacc atcgatatcc atttggttag aaccaatcat
     5821 aaagtctacg tgaacatctg aacggttaag ccctgcagct tcaagctcct cttcgctcat
     5881 ctccgctcca tcaacaacgc tagtcgcata ggctgcaccg atagccaagt ggtttgacgc
     5941 attttcatcg aaaagggtgt taaaaaaggt aatgcctgac tgagaaattg gacttggatc
     6001 tggtaccaag gcacattcac ccaaggcacg cgcacccgca tttttaaaga caaggtcttt
     6061 cataacctga tcacccttct cagcagtgat atctacgatt tgtccatcct taaaggtcac
     6121 cttaatgcct tcaatgatat ttccgttgta gctaagcggt tttgtagaag tgacataacc
     6181 atctgcacga cggaagtcag gcgctgtgaa gacctcttct gtcggcatat ttggcaagaa
     6241 ttcttcgccc tgtgcattga cagcaccagc tgattcccaa acgtggttct ttggcaaacc
     6301 aagtgttaaa tctgttcctg gcgctgtgta gtgaagggct gaaaattgct ccttattaag
     6361 catatcggcc ttgctcttga gaatggctgc atgttcctcc caagccttaa caggatctgc
     6421 ttcgtagaca cgacaagttt tgaagatttg atcccaaagg aaatcaactg cttcttcgtc
     6481 gctcgcagca tttgggaaga ctttcttagc ccactcaagt ccagcagcgg ctgctacagt
     6541 ccagctaacc ttgttagatt gagttgcgat acgcataggc ttcatggcaa gtcccatagc
     6601 tttagcagaa gctgaaagct tgtcagcgtc cactccgttc aaggcacctg gatcagatga
     6661 acgaacccca agacggctag ccttgttctc caaaagatag ttcatctcag caatcttgta
     6721 ttctggcaca ttgtccaaac gctccatcgg ggcatggagg aatttctcac ggttaatcac
     6781 atcatctgtc cactgaacga tgacctcatg cgcacccaag gcataagctt ctttcacgat
     6841 tagatgtgcc aattcacgtt gctccacatc aatagagaga gccaaagtgt gaccaggttg
     6901 cacgttaatt ccgttcgcaa ccaacaattt cgcatatttt cctagatttt ctttaaaatt
     6961 tggtaaaacc attctgtttt ctcttttcta tttttatttt tctttcaaag cagaaaagat
     7021 tcctgctaaa gcaatagcac ctgacaagag tgctgtcgat agaagaattg tacgatcagc
     7081 aagttctaat tgatattcaa ataccttctt agccggctta tcttccgcaa atattcttag
     7141 tttcatgaga acccccttaa aatagattaa aataaatcac tgtgactgcc tgtcctcagc
     7201 aaatttaaaa tcaattccga cttgtctact ttataaacca aaagccaatc tggctgggta
     7261 tggcattcac gaactccttg aaaatgcttg gatgccgtca atgaatgatc acgatatctg
     7321 gcaggatgtt ctttttcttg aaccagaaaa ttcaaaactt cttctaataa ttctgccttc
     7381 aaaccacgct tcatagccaa cttaaaatct tttttaaact gtttatgata acgaatctta
     7441 agcacgtaag tcctccatca aatctgagac tgattcaaaa gactggctca tattacgatt
     7501 ttggtctaaa tccgttaacg cttggagcaa cttccgattt tcgtctagtc taacatcaaa
     7561 aggtaatccc tgatattgaa ttgcctgacg aaggaaaata ttaatagctg ttgtcatatc
     7621 cattcccaga ttactaaaca cctgttgggc ctgctcctta acctcactat ccagacggat
     7681 gcttatactc atctttgaca tactctcacc ctctttccat agactatttt aacaaaaaag
     7741 aaagctaatg taaatctatt ggatatacgt tagcctcttt taatagatta ttaagcaatt
     7801 ttttaaaaca actcatcaaa caaactcaac tggttatcct ctggcatatt tccaagaata
     7861 cccatctcat ccatcttttc aaccaaggtt gatgagagtc caccacgctt gcgtagttct
     7921 gttttagaga ggaattctcc ctcttcacgc gcccgcacca gttgcttggc aacgttctct
     7981 cccagaccat ccattgctac aaatggtggg ataagggtat ccccgtcgat gaggaactct
     8041 gtcgcctgac tacggtagag atctaattta ccaaacttga aacctcgttc ccacatctca
     8101 ttgacaatct caagagttgt atagagatcg atttccacat tagaggcttc attgttcttc
     8161 cgtttttcag agatttcttc cattctgcgc ttgatgacct ccaagcccgc acccatggtc
     8221 ttgatatcaa aagccttagc acgaatggag aagtaagcac agtagtaata aataggatgg
     8281 tgaaccttga agtaagctac acgcaaggcc atcataacgt aggctgccgc atgggcctta
     8341 gggaacatgt acttaatttt cccacaggat tcgatatacc actctggcac cttattagcc
     8401 ttcatggctt cgatatagcc atttctctcc tcttctgaaa tctttagcca caaaccctta
     8461 cgtacccgtt ccataatggt aaaggccatc ttaggttcca gacccgcatg catgaggtaa
     8521 accatgatgt cgtcccgaca accgataaca gtcgataggt ccgctattcc ttgcttaatc
     8581 agatcctgag cattccccaa ccaaacgtca gtaccgtggg acagaccaga cagctgaagc
     8641 aattccgcaa aggttgtcgg atgggtttcg tctaccattc cacgtacgaa atttgttcca
     8701 aactctggaa tccccaacat acccgtaggc gttccaattt gttcaggtgt tacccctagt
     8761 acatcagtcc cagaaaagag tgccatcacg ccttcgtcat ccataggaat tttattaggg
     8821 tcaataccag acaaatcctg aagttttcga atcatggtcg gatcatcatg tcccagtaca
     8881 tcgagtttga ggacgttctc atcgatatcg tggaagttaa agtgagtggt ctgccattca
     8941 gccgtgacat catctgctgg atactggaca ggcgtaaaat cgtagacatc catgtagttc
     9001 ggaataacaa cgattccccc cgggtgttgg cctgttgtcc gcttgacacc cgccgctcct
     9061 tgagcgaggc gttctacttc tgcatcacga taaaacttgc cataatctcg ctcgtaaccc
     9121 ttgacaaatc cataggcagt cttggcagct accgtaccaa ccgttcccgc acggaaggca
     9181 tattcttcac caaagatatc acgcacatcc aagtgggcgc taggctgatc ttctcccgag
     9241 aagttcaagt caatatcagg aaccttatcc ccatcaaaac caaggaaggt ctcaaacgga
     9301 atatcctgtc cgtttttact gagtttgtga ccacagtttg gacagtcctt atggggcata
     9361 tcaaatcctg aaccgtacga accatctgtg ataaactcac tgtactgaca ctgaccacag
     9421 acatagtgag gagagagagg attgacctcc gtaatcccaa tcatggtcgc aacgaaacta
     9481 gatccgacag acccacgaga accaaccaaa taaccccgtt cattagaacg ttgcaccagc
     9541 atctgcgatg ccagataaat cacagcaaat ccattcccca gtatggatgt taattctttt
     9601 tcaatccgca aatcaacaat atctggcagc ggatttccat aaatctcaaa agctttctta
     9661 taggtcaact cagcaactgt ttcttcagcc ttgtcgatga aaggcgtata caagtcaccc
     9721 ttaacgactt caacggattc aaatatttct gccaaggcat tggtgttttc aataaccagt
     9781 ttacgagcca gttcctctcc caaaaaggca aattcatcca acatctcatt agtcgttcga
     9841 aaatgagcct ttggaagtgg tgctggttgg gcatgttcac catgaccgat agttcgatta
     9901 atcatcgcac cctgtcccaa actacggacg ataatttcac gataaatctc ttcttccggt
     9961 tcgatatagt gaacatttcc cgtagccaga acaggcttgc caaggcggtc tccaacctct
    10021 atcaaactct tgataatggt ctggagttcc tccatatcct tgacctgctc tttggcaatc
    10081 aagggtgcat agatagccgg tggcatgacc tcgataaaat cataatactt ggccacctca
    10141 accgccgcat ccacaccttg agaaacgacc acgtcaaaaa cttcaccctc tgaacaggct
    10201 gaacctaaaa tcaagccctc tcgatgggca tctagaaccg ttctcggaat ccgtggcact
    10261 ccttcaaaat acttggtatt agacaaggaa accagcttaa agatattttt tagacctacc
    10321 tgattcttga catagatggt cgcatgcttg atccgagctt ttttgtaaga atctggactg
    10381 attagatcaa tgttgagtct agctaaatcg gtcacaccat gtttttctgc tacctctttg
    10441 ataaagatga aaagcagacg accagtcgct tccgcatcgt agttggccat gtggtgatgt
    10501 tccaaggcca caccaaaacg cttggtcaaa ggccccaaac catggcgttt atactcagga
    10561 tagaggtttc tagcaaactc cagcgtatca ataactggct gactaatctt tggaagatca
    10621 tgccgctcat aattagcatt cataaagcca acgtcaaagg tagcattgtg ggcaactagg
    10681 accgtatcct tgcaaaattc ttggaattct tgcaaaactt gttctagtgg tttggcattt
    10741 ttgacatgat catctgtaat tccagttaac tctgtagtaa aggctgacaa gggatgccca
    10801 ggattgataa attcatcaaa ttcagcaata acattcccct tgtacatctt agaagccgca
    10861 acctgaatca agtcattata gatagctgaa agtcccgtcg tttccacgtc aaagaccacg
    10921 taggttgctt ctgacaagtc catctccact tcgttataga cgatagggac acggtcctcc
    10981 acgatattgg cttccatccc atagatcagc tggattcccg ctttcttagc cgccttatag
    11041 ccatgtggaa aggactggac attcccatgg tccgtgatag caaccgcctt gtgtccccac
    11101 ttagcagctg ttgcaacaat ctcttcgacc tctggcaaag catccatagt cgacatgtta
    11161 gtatgagcat gaaactcaac ccgacgctca ccttctggca tcaaatcctt ccgctcatag
    11221 tgaacaactt cctgcagatc ctgtacgttc atagtcaaat cgcgtgtgaa gttattcatc
    11281 tccacattcc ctcgaactcg gagccaagaa ttcttcttga tgaggtcaaa cttctgggcc
    11341 tcttcctcgt ttttaaccca cttttgcata gaaaaacttg aagtatagtc cgtcatttta
    11401 aagttgatta aaacacgacc tgttctagtc actttttgct ccacatcaaa aacaacccct
    11461 tcaaatacca gacgattttc ctctgtcgtc acttcgatca taggagtaat ctccgcctta
    11521 tccagcttgg gtttagctgc agcttttttc gcttgaaaat caaaggctgg tttctcttcc
    11581 gctggaggag gtgccatctg ctccagttgt tccatagcac ggagcgcttc ctcattggca
    11641 gcttgaacaa tctgctcatt ttcagcatga aaggcctctt cctgctcttg ggtcaggaca
    11701 tcattcttct cgacttgaca gttaaaagtt ggaaaaccaa acttttcaag ttgtttggct
    11761 aaattaggaa gatgattctt cttaaaatgt tccttatcaa tcgcttcaga tccttcaata
    11821 aatagctgat taccctcagc acgaacttgc aaattttgat aaagggactt aaaaccttga
    11881 ctagcacatg gaccttcaga gaaagcctcc ctatagtagg actgcaagag ctgatttgaa
    11941 aattcttgag accgagcctt aatttcaaaa acagctttat tgcctgtctt agaaaattct
    12001 tcgctcaaac ctttctttaa ttctaaaaag atttcaatcg gtaaaatatt agaaaatacg
    12061 aaatgaaact cccatacctt actaatttta tgaaccacaa ctcgctcaat attggcctgt
    12121 gctaaagcag gagcctgtct catttcagca ggcatcccca attgattcat caaaatttca
    12181 aaactatttg acattcattt tcctcacatt attcttctac tattttacca tatttagagg
    12241 tattttctaa agacaaaagg aagccactaa gtgacttcct tctagagtga ggacggatta
    12301 gtcttcacct ttatttttct taataatttc ttcttgtact gacttaggta catcttcgta
    12361 gtggtcaaat accatcatga atgtaccacg tccttgagat gcagaacgaa gaactgttgc
    12421 gtaaccgaac atttcagcaa gtggaacgta agcacgaacg atttggctgt taccgtgtgc
    12481 ttccatacca tctacacgtc cacgacgagc agttacgtga cccataacat caccaaggtt
    12541 ttcttctgga acagtgattg ttacaagcat cattggttca aggatagctg gttgtgctga
    12601 tttagcagct tctttaaggg aaagtgaagc cgcaatcttg aaggcagttt cagatgagtc
    12661 gacatcgtga tatgaaccat cataaagctt agctttaacg tcaaccattg ggtaacctgc
    12721 aagaacaccg ttagccatag attctaccaa acctttttca accgctggga taaattcacg
    12781 aggaaccaca ccaccgacga ttgcgttttc gaattcgaat cctttacctt cttcgtttgg
    12841 agtaaattca atccatacat caccgaattg acctttacca ccagactgac gtttgaagaa
    12901 tccacgtgct tgagtagaag cgcggaatgt ttcacggtaa gatacttgag gagcacctac
    12961 gttcgcttca actttgaact cacgacgcat acgatcaaca aggacgtcaa ggtgaagttc
    13021 acccatacct gagataactg tttcaccagt ttcaacgttt gtttcaacgc ggaatgttgg
    13081 atcttcttca gccaattttt gaagggcgat acccatcttg tcttggtcag ctttagattt
    13141 tggctcaacc atcaattgga taactggttc tggaacgttg attgactcaa ggatgatttt
    13201 agctttttca tctgtcaatg agtcaccagt tgtagtatct ttcaaaccaa cggcagcagc
    13261 gatatcacct gagtaaacag tgtcgatttc ttgacggctg ttagcgtgca tttgaaggat
    13321 acgtccgata cgttcacgtt tacctttaga agtattcaat acgtatgaac ctgattgaag
    13381 aacacctgag taaacacgga agaatgtcaa acgacctacg aatgggtcag tcatgatctt
    13441 gaaggcaaga gctgcaaatg gctcttcgtc agatgctgga cgaatttctt cagcgtctgt
    13501 atctgggtta atacctttga ttgctgggat gtcaagtggg cttggaaggt agtcgataac
    13561 cgcatcaagc atcaattgaa cacctttgtt tttgaaggct gaaccacaca atactgggaa
    13621 gaattcaacg ttgatagtcg ctttacggat accagctttc aattcttcgt tagtgatttc
    13681 ttcaccttcg aggtatttca tcatcaattc ttcgtcagtt tcagcaactg cttcaatcaa
    13741 tttttcacgg tattcttgag cttggtcaag gtattcagct gggatgtctt cttcaaggat
    13801 atccgtacca aggtcgttag tatagatttc agctttcatc ttgatcaagt caatgatacc
    13861 acggaagtca tcttcagaac cgattggcaa ttggattggg tgtgcatttg cttgaagacg
    13921 atcgtgaagt gtgcttacag agtaaaggaa gtcagcaccg attttgtcca ttttgttggc
    13981 aaatacgata cgtggaactc cgtactcagt tgcttgacgc caaactgttt cagtttgagg
    14041 ctcaacacct gattgtgagt caagaacggt aaccgcacca tccaatacac gaagagaacg
    14101 ttgtacttcg attgtgaagt ccacgtgtcc tggtgtgtcg atgatgttta cgcggtggtt
    14161 gttccattga gctgtcgtcg cagcagatgt gatcgtgata ccacgttctt gctcttgctc
    14221 catccagtcc atttgtgacg caccttcgtg agtttcaccg attttgtgga ttttaccagt
    14281 gtagtaaaga atacgctcag tagttgttgt tttaccggca tcgacgtgag ccatgatacc
    14341 gatattacga gttttttcaa gtgaaaattc gcgtgccatg aggtttgttt ctcctattta
    14401 tttttgattt ctattctatt ataacacgat tttaataaaa acggataggc aggacctacc
    14461 cgttctcaat gttttcatgc tattgttggt ttcaacttac gagatggtaa gctgagttat
    14521 agctaatact aatcgattta gctaatttga acccgggcta aagttagtta gccgatgtga
    14581 gctggaacgg gatgctgcgt gaaaaagata aaactccttg tattcgtcga atactgcgtc
    14641 agtttcctat ttttaccttg catccttacc gttcctagca tcatgattta gttgagctca
    14701 agctaaaagt ctggagaaaa agatgaatct cattggttgc aaccgcaacc tgcttcgatt
    14761 ccctattttc tctgggactt tcttaacgct ttcgcatcct atcttaccaa cggaagtgtg
    14821 cgaatgcacg gttagcttca gccatacggt gagtatcttc acgtttctta actgctgcac
    14881 cagtgttgtt agcagcatcc aagatttctt ttgcaagacg gtcttgcatt gtgtgttcac
    14941 cacgaagacg agcgattgtt accaaccaac gaagtccaag tgttgtacga cgttctggac
    15001 gaacttcaac tgggacttgg tagttagaac caccaacacg acgtgcacgt acttcaagta
    15061 caggcatgat gttttccata gctgtttcaa atacttcaag tgcatcgttg ccagtagctt
    15121 ctttgatttg ctcaaaagca ccgtaaacga ttgaagcagc agtaccacgt ttaccatcaa
    15181 gcataacgcg gttgataaga cgagtaacta gttgtgaatt gtatagcgga tctggcaata
    15241 cgtcacgttt tggagctcta tttttacgac tcatttctct ttatcccctt tccttatgct
    15301 tttggacgtt tagtaccgta tttagaacgg ccttgtttac gatcgttaac acctgcagta
    15361 tcaagtgcac cacggacgat atggtaacgt acccctggaa ggtcttttac acgtccaccg
    15421 cgaagaagca ccacgctgtg ctcttgcaag ttgtgtccga tacctgggat gtaggcagta
    15481 acttcgataa ggttgctcaa acgtacacga gcgaatttac gaagggctga gttaggtttt
    15541 ttaggtgtca ttgttccaac acgagttgca acaccacgtt tttgtggtga agaaacgttt
    15601 gtttgaactt ttttatgact attgtaacca acgttcaaag ctggtgattt agatttttct
    15661 acttttgatt tacgcggttt gcgaaccaat tggttaattg taggcatcta cattctcctg
    15721 tgttttttta tttttggtga tgatacactt ggtgacagat atcatctgtg tgtacttttg
    15781 caacatttgt cagcacgtcc ctgtacactc ttgagagacc aaaagtaaaa agtaccgtct
    15841 attattgtaa caaaattttc ccttgcttgt caagatattt ttctttttta ttggtaatgt
    15901 tagagatcaa tttctgaata aaaatagctg agaacacatc atcttcctaa taacacggct
    15961 tggcttacgt gacattttta tctccgtcat ttatactgat atataaaata gtacggaaaa
    16021 cttctcaaaa gtaagaattt ctttcacaaa tcaaagaaaa cgcttgcata ttgttttact
    16081 acatgctata ctgatataga aatttattga ttggagaatc attatgagaa aaacaccatc
    16141 tcacactgag aaaaaaatgg tctacagcat ccgttccctc aaaaatggaa ctggttctgt
    16201 ccttatcggc gcaagccttg tcttgcttgc catggctaca ccaactatct catccgacga
    16261 aagtacacca accactaacg aacccaacaa cagaaataca accacccttg cccaacctct
    16321 tactgataca gcagctggct ctggtaagaa cgaaagtgat atttcttcac ctggaaatgc
    16381 aaacgcttcc ctagagaaaa cagaagaaaa acctgctgca agcccagccg atccagcacc
    16441 acaaactgga caagatcgtt caagtgagcc aactacttct actagtccag taacaactga
    16501 aactaaggca gaagagccca tcgaagataa ctacttccgt atccatgtca aaaaacttcc
    16561 tgaagaaaac aaggatgctc aaggactatg gacttgggac gatgttgaaa aaccatctga
    16621 aaactggcca aacggagctt tgtccttcaa ggatgccaag aaagatgact acggctatta
    16681 cctagatgtc aaattaaagg gagaacaagc caagaaaatt agcttcctca tcaacaatac
    16741 agctggaaaa aatctaaccg gcgataaatc tgtagaaaaa ctagttccaa aaatgaacga
    16801 agcttggtta gaccaagatt acaaggtttt ctcttacgag ccacagcctg caggaactgt
    16861 tcgcgtcaac tactaccgca cagatggcaa ctatgacaag aaatctctct ggtactgggg
    16921 agatgtgaaa aatccaagta gcgctcaatg gcctgacgga acagacttta cggctacagg
    16981 caaatatggc cgctatatcg acattcctct taatgaagcc gcaagagaat ttggattttt
    17041 attactagat gagagcaaac aaggagacga cgtgaaaatc cgtaaagaaa attataagtt
    17101 cacagatttg aaaaatcata gccaaatttt cctaaaagac gatgatgaat cgatttacac
    17161 aaatccatac tatgtccatg atatccgtat gacaggagcc caacacgtag gcacttctag
    17221 cattgaaagt agcttttcaa cacttgtcgg tgctaaaaaa gaagatatcc tcaaacactc
    17281 caacatcact aatcacctag gaaacaaggt aactattacc gatgttgcaa tcgatgaagc
    17341 tggtaagaaa gtgacctaca gcggagattt ctctgacaca aaacatcctt atactgttag
    17401 ctacaattcc gaccaattca ctaccaaaac aagctggcgc ctgaaagatg agacatacag
    17461 ctatgatggc aaactgggag ctgacctaaa agaagaagga aaacaagttg atttgaccct
    17521 ttggtcacca agtgctgata aggtttctgt tgttgtctac gacaagaatg accctgacaa
    17581 agtagttgga actgtcgctc ttgaaaaagg ggaaagagga acttggaaac aaactctaga
    17641 cagcacaaac aaactcggaa tcacagattt cactggctac tattatcaat accaaatcga
    17701 gcgtcaaggt aaaactgttc ttgcactcga tccttacgct aaatctcttg ctgcttggaa
    17761 tagcgacgat tccaagattg acgatgccca taaagtggct aaagccgcct ttgtagatcc
    17821 agctaaactc ggacctcaag acttgactta tggtaagatt cacaatttca agactcgtga
    17881 agacgccgtt atctacgaag ctcatgtgcg tgatttcact tcagatcctg ccattgcaaa
    17941 agacttgacc aaaccatttg ggacttttga agccttcatt gaaaaactag actatctcaa
    18001 agacttgggt gtaacccata tccagctcct tccagtcttg tcttactact ttgtcaatga
    18061 attgaaaaac catgaacgct tgtctgacta cgcttcaagc aacagcaact acaactgggg
    18121 atatgaccct caaaactact tctccttgac tggtatgtac tcaagcgatc ctaagaatcc
    18181 agaaaaacga atcgcagaat ttaaaaacct catcaacgaa atccacaaac gtggtatggg
    18241 agctatccta gatgtcgttt ataaccacac agccaaagtc gatctctttg aagatttgga
    18301 accaaactac taccacttta tggatgccga tggcacacct cgaactagct ttggtggtgg
    18361 acgcttgggg acaacccacc atatgaccaa acggctccta attgactcta tcaaatacct
    18421 agttgatacc tacaaagtgg atggcttccg tttcgatatg atgggagacc atgacgccgc
    18481 ttctatcgaa gaagcttaca aggctgcacg cgccctcaat ccaaacctca tcatgcttgg
    18541 tgaaggttgg agaacctatg ccggtgatga aaacatgcct actaaagctg ctgaccaaga
    18601 ttggatgaaa cataccgata ctgtcgctgt cttttcagat gacatccgta acaacctcaa
    18661 atctggttat ccaaacgaag gtcaacctgc ctttatcaca ggtggcaagc gtgatgtcaa
    18721 caccatcttt aaaaatctca ttgctcaacc aactaacttt gaagctgaca gccctggaga
    18781 tgtcatccaa tacatcgcag cccatgataa cttgaccctc tttgacatca ttgcccagtc
    18841 tatcaaaaaa gacccaagca aggctgagaa ctatgctgaa atccaccgtc gtttacgact
    18901 tggaaatctc atggtcttga cagctcaagg aactccattt atccactccg gtcaggaata
    18961 tggacgtact aaacaattcc gtgacccagc ctacaagact ccagtagcag aggataaggt
    19021 tccaaacaaa tctcacttgt tgcgtgataa ggacggcaac ccatttgact atccttactt
    19081 catccatgac tcttacgatt ctagtgatgc agtcaacaag tttgactgga ctaaggctac
    19141 agatggtaaa gcttatcctg aaaatgtcaa gagccgtgac tatatgaaag gtttgattgc
    19201 ccttcgtcaa tctacagatg ccttccgact taagagtctt caagatatca aagaccgtgt
    19261 ccacctcatc actgtcccag gccaaaatgg tgtggaaaaa gaggatgtag tgattggcta
    19321 tcaaatcact gctccaaacg gcgatatcta cgcagtcttt gtcaatgcgg atgaaaaagc
    19381 tcgcgaattt aatttgggaa ctgcctttgc acatctaaga aatgcggaag ttttggcaga
    19441 tgaaaaccaa gcaggatcag tcggaattgc caacccgaaa ggacttgaat ggactgaaaa
    19501 aggcttgaaa ttgaatgccc ttacagctac tgttcttcga gtctctcaaa atggaactag
    19561 ccatgagtca actgcagaag agaaaccaga ctcaacccct tccaagcctg aacatcaaaa
    19621 tgaagcttct caccctgaac atcaagatcc agctccagaa gctagacctg attctactaa
    19681 accagatacc aaagtagctg atgcggaaaa taaacctagc caagctacag ctgattcaca
    19741 agctgaacaa ccagcacaag aagcacaagc atcatctgta aaagaagcgg ttcgaaacga
    19801 atcggtagaa aactctagca agaaaaatat acctgcaacc ccagatagac aagctgaact
    19861 tccaaataca ggaattaaaa acgaaaacaa actcctattt gcaggaatca gcctccttgc
    19921 gctccttggt ctcggtttct tactaaaaaa taaaaaagag aactaaacta gccctcctat
    19981 agaaaaatcc cccaagcatt atagctcggg ggattaattt tcgtacaata tttgttgtcc
    20041 taataaactt gattaggatt ttttattaag cctctttcat agcaaaataa gctcgtactt
    20101 tgggtgcaac ttgtgttccg aagagttcaa tagctctcag aacctggtca tgaggcatag
    20161 aaccaagcgg tagatgaagc atgaagcggt ccaatcctaa atcctctatc atgcgaatca
    20221 atttttcggc cacctgatct ggattgccaa caaacatggc gccatttgac cctacctgct
    20281 ccaaatattg ctcataacgc aattcctgcc agtgcggacg gtctttggaa atagcatcca
    20341 ccacttgctt agtcggatgg aaataatctt tcaccgcctg ctcaccatct tccgcaatcc
    20401 acccccaaga atgggctccc actttcaagt ctttgtcagc atggaccgct tcgcttccaa
    20461 tctcacgata agcctgaatc aactttttaa aataacgtgg attaccacca ataatagcat
    20521 atacaatcgg tagaccagcc tgagcaatct tcactgttga ttcgacatga ccacctgtag
    20581 ctatccacaa gggcaatttg tcctgaactg gacgaggata aacttcttta ccagcaatcg
    20641 tttgagtcaa tcgaccttgc cagtctaact tggtcttttc attgactaac tgaagcaagt
    20701 ctaatttctc atcaaaaaga gagtcgtagt ctttcaagtc ataaccaaac agagggaaag
    20761 attccgtgaa agagcccctt ccagccataa tctccgctcg tccatttgac aaagcatcga
    20821 tagtggcata ctgttggaac aaacgaatcg gatccatgct tgacagaatg ctgactgcac
    20881 tggtcaaacg gattttcttg gtattgactg ccccagcggc caggacaatc tctggggctg
    20941 atactgcaaa atccgcccga tggtgctcgc caatcccata tacgtccaaa ccaaccttgt
    21001 cagccagctc aatctctgcc accaactggc gaatgcgttc agcatgactg taagtttgtc
    21061 cagtcccttc aagctccgtt atttccccaa atgttgaaat tcccaattct accattgtga
    21121 ttctccttgt ctatctctgt ccttcaattt gaaaaattat tctaacactc aatgaaaatc
    21181 aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac agtgttttga ggttgtggat
    21241 agaactgacg aaatcagtaa ccatacctac ggcaaggcga cgttgacgtg gtttgaagag
    21301 attttctaag agtataacac gaatcttgag tacaagcaac caatttgctc acaagaaaaa
    21361 gcctagataa ctagactttt ttagcttatt ctaccgttac tgacttggca aggttacgtg
    21421 gtttgtccac atcgaggcca cggtggaggg ttgcaaagta agcgactaat tgcgttggta
    21481 cgaccattga aattggtgag aggtatggat gtacggtcgt aaggacgata tcgtcggtat
    21541 ctttggctac attctcttct gcgatagtga ggactttggc accacgggct gcgacctctt
    21601 ggatatttcc acgagtatgg ttggcaagaa ctggatctga caagagagcc aaaacaggcg
    21661 ttccttcttc aatcaaggca atggttccgt gcttgagttc tcctgccgca aaaccttcac
    21721 actggatata agaaatctct ttgagtttga gacttgcttc catggctacg taataatctt
    21781 gaccacgtcc gatgtaaaag gcgttacgag ttgtttcaag aagttcacga accttggctt
    21841 caatggtttc tttctctgaa agagttgatt caatagactg agctacgatt gacaattcat
    21901 gaaccaggtc aaaggcttgc gctttagcat taccatttgc ttctccgact gcttttgcaa
    21961 ggaaggcaag ggctgcgatt tgcgctgtat aggctttagt tgatgccacg gcaatttcag
    22021 gacctgcgtg aaggagcatg gtatagttgg cttcacgtga gagggttgaa cctggaacat
    22081 ttgtcactgt taagcttgga attcccattt cattagcctt gaccaaaact tgacgactat
    22141 ccgctgtttc accagattgg ctgataaaga tgaagagtgg tttcttgctg agaagtggca
    22201 taccgtagcc ccactcagat gagattccaa gttcaactgg tgtatctgtc aattcttcca
    22261 acatcttctt agaagcaaat cctgcatggt aagatgttcc agctgcaagg atgtagatgc
    22321 ggtctgcgtc ttgaacagcc ttaatgatat ctgggtctac gacaacttga ccagcctcat
    22381 ctgtgtaggc ttggatgagt ttccgcataa cagttggttg ctcgtcaatt tccttgagca
    22441 tgtagtaagg gtaagttccc ttaccgatat ctgacaagtc aagttcagca gtgtagctag
    22501 cacgctcacg acgatttcca tcatagtctt gaacttccac gctatcagcc ttgacgatta
    22561 ccaactcttg gtcatgaatt tccatgtatt ggttggtttc acgaatcata gccatagcat
    22621 ctgagcagac catattgtag ccttccccaa gaccaatcaa aagtggagat ttgtttttcg
    22681 ctacatagat gacatctgga ttttcagagt caatcaaggc aaaggcatat gaaccacgga
    22741 taatatgaag agctttttta aaggcttcaa gaactgagag accgtcttct tccgcaaatt
    22801 ttccaatcaa atgtacggcg atttccgtat ctgtttgccc tttgaagtgg tgcccagcaa
    22861 ggtattcttc tttaatttca aggtagtttt caatcacccc attgtgaacc aagacaaaac
    22921 gttctgtctc agagcggtgt gggtgagcat tgtcttccgt tggtttccca tgagttgccc
    22981 aacgagtatg tccgatacca gttgttccct caacaccagc tgtcttggca gacaattctg
    23041 cgatacgacc aacagccttc accaaatggt tatcagcacc atctaggaca aaaattcccg
    23101 cagaatcata gccacggtat tcaagctttt caagcccttg aatcaaaata tcagttgcat
    23161 ttgtgtttcc aacaacacca acaattccac acatagtata tacgacacag gcaagctgtg
    23221 ctttctcctt aaaattggta tagtctaatt catcttttat agaatcagca aaaacagtat
    23281 atacttgttt ctttcacttg tcaagagtaa aaattggtat agttcaaatt aagctcctgt
    23341 aagcaaaaaa ctctgaccga ttgggataat cagtcagagt cctttttaaa atccattatt
    23401 atcgcttaat tttttgaacc agtggcctga tttcttcaga cgacgttctt gcgtttccaa
    23461 gtctaattcg accaaaccat agcgattttt atagctgttg agccatgacc agcagtcaat
    23521 aaaggtccaa atcaagtagc ccttacagtt ggcaccatct tcaatggcac ggtgaagttc
    23581 acgaagatga ccttttacaa agtcaatacg gtaatcatct tgaatcattc catcttgacg
    23641 gaatttttct tccccttcaa cacccatacc attctcagtc aacatccatt caatattgcc
    23701 ataattttcc ttgatatttt gggcgatgtc ataaatccct tgctcataaa tctcccaacc
    23761 acggtgagaa ttgattttac gtccaggcat cacataaggc tcgtaaaaat gttctggtaa
    23821 gagtggactc tctggatgct tagcaaatcg aggagccata acacgcaaag gttgatagta
    23881 gttcacacca aggaagtcca ccgtattatc atgaatgagt tccaactctt cctctgtagc
    23941 atcaggtaaa agaccgtgtt catgcaagat ttctaccaac tcctgtggat aagtccccaa
    24001 gacagatgga tctaagaaag attgggcctg aaaaagggcc gcaatacgag ctgccttgac
    24061 atcagcagga tgctggctac gtggataagc cggtgtcaag ttgaggacaa tcccaatctt
    24121 ggaatcaggc aaaagttcat ggcaagcctt aacagcccgg ctgctggcca attgtgtatg
    24181 ataggctacc ttaacagctg cctctgcatc caccttatgt ggataatggg catcataaaa
    24241 ataaccaaat tctacaggaa cgatgggctc gttaaaggta atccattgat ccactaaatc
    24301 tccataagtc tcaaaacaaa aacgagcata gtcttcatag gctgagactg tcgccttatt
    24361 ttcccaacca tcaccatcct cttgaagggc aaaaggtaaa tcaaaatgat agagattgac
    24421 taacagacga attcctttag ccttaatagc ctcaaagacc ttacgataaa aatccacacc
    24481 ttgagggttg acttttccac agccttgtgg aaaaatccgt gaccactgaa tagaagtccg
    24541 aaagactgtg tgaccagtct ctaacaaaag ctcaatatcc cgctcccaat tttcataaaa
    24601 agtcgatgtc ttatctgaac caatcccatt atagtaacga tttggctcca cttggaacca
    24661 gtaatcccag agattgtctc ccttaccgtc accagctaca cgtccttctg tctgcggtcc
    24721 agaagtagag gatccccaga caaaatcctt tggaaatctt agcataacat ttacctcttt
    24781 atctactcat ttctcccatt atacagaaaa aacaaggtaa aaactagtta cattttttcc
    24841 ttgtttttct tctgattata gtttttattt cttgcttagg atttcaagcg tttcaagcac
    24901 gttatctgca tgaacctcaa tggtgtcacc agttgccttg atcttaactt ctacaatgcc
    24961 atcggccgct tttttaccaa cagtgatacg gattggaaga ccaatcaagt cactatcgct
    25021 aaatttaaca ccgacacgtt cgttacggtc atctgtcaag acttcataac cagctcccat
    25081 caagcttgct tcaagttttt ctgtcaaggc ttgcgcttct tcatccttga cattgacagt
    25141 aatcaaatgc acatcaaatg gtgccaattc tttagggaaa ttgattcccc aagcgtaacg
    25201 gtattcacct tttggcgttt tgttaacaaa gaggcgagcg tgttgctcca tcactgctga
    25261 aagaagacgg ctgacaccga taccgtaaca tcccatgatg attggcacag cacgaccatt
    25321 ttcatccaag acatctgctc ccatgcttgc tgagtagcga gttccgagtt tgaaaatatg
    25381 accgatctca ataccacgcg caaagttaag gacaccttgt ccatctgggg aaatttcacc
    25441 ctcacgaact tcacggatat ccacatattc tgcagtaaaa tcacggcctg ggttcacacc
    25501 agtcaagtgg tagccatctt cgttagcacc gacaactgca ttgcgaacat cttgcacctt
    25561 acgatctgca ataattttaa tattctctgg caaaccaact ggtccaagtg aaccaaatcc
    25621 tgcttgaaca acattcgcca cttcttcttc gctagcaacg tcaaagaaat ctgctcctaa
    25681 gtggtttttc aacttgactt cgttgagttg gtcatttcca actagaaggg ctgcaacaag
    25741 ctcaccatct gcaatgtaga agagggtttt aatcgtttgt tcttctggaa cattgaggaa
    25801 agctgcaact tcatcaattg atttaacatc tggcgttgca acacgagtaa cttcttcttc
    25861 agcgacaaca cggttgcttg gtttgtactc gtttgttgcc atttctaagt tagctgcata
    25921 gctagactca cttgagtaag caatggtatc ttcaccagag actatccatt tgagcaattc
    25981 tgccttgatt tcttcttgca cttctgcagg aatttcgtca aatgaggcaa ctgacttgtc
    26041 caagacaacc cagcggtcaa ggtctgtacg agcagatgta atggccataa attcttggct
    26101 atccttacca cccatggctc caccgtcacc aataatagcc ttgaagtcta aaccactacg
    26161 agtgaaaata cgctcatagg ctgctttgta ctcatcataa acactatcca aactatcata
    26221 gttagcgtgg aaactataag catccttcat gataaactca cgtgtacgaa gaagtccatt
    26281 acgtgggcgt ttttcatcac gatacttggg ctgaatttga taaaggttga gtggcaattg
    26341 cttgtaagat ttaacagaat cacggacaat agctgtaaag gtttcttcgt gagttggacc
    26401 taagataaag tctgattttt cacggttttt tagtttgtaa aggtcttcac cataggtttc
    26461 gtaacgacct gattcacgcc acaattctgc actaagaagg gctggagcca acatctcaac
    26521 agcaccaatc ttttcgaatt cttggcgcat gatgttttta gctttttcaa tcacacgatt
    26581 ggcaagtggt agataagaat aaacacctgc tgaaacttgg cgaacataac cagcacgcaa
    26641 cataagagca tggctgataa cttgagcatc gcttggcatt tcgcgaagcg ttgggatagg
    26701 cattttactt tgtttcataa tattcctcga ttatctaaaa aagagtcgca taatgtcatt
    26761 ccaagtcaca gcaatcatca agacaaccat gatgaccact ccggccaagg tgacataggt
    26821 ttcaatttct tgtttcaatg gtttgcggcg gatggcttct aggatattga gcacaatctt
    26881 accaccatcc aaggctggaa tcggaataag attaaaaatc ccaatattga tggaaatcat
    26941 tgccaagaag tacaagatat tttcaattcc atttttagca gcatcactac ttgccttaaa
    27001 gatagcaaca ggtccaccca acttgttcaa atccggttgg aaaatcagat ttttcagagc
    27061 tgagagaatt cggagagctg agtcagcagc agttgtaaaa ccacctacaa acatggatag
    27121 aaaatctgac ttaacccccg gttgaacacc tagaaggtaa cgaccttgac tatcttcggg
    27181 tgtaacagtg acttgtttgt cactcccctt ttcagaaata gtcacatcca aagtcggtgc
    27241 cgtcttatct ttggtttctg tttccacagc ttggatcaag ctttcccagt tgctaacctc
    27301 atgtgagcca atcttggtaa tttgtgccgt ttctggtact cctaccttgg ccaaggcacc
    27361 ttggggcatg atatggaact gattggtatc aacatctctg acaccaccct gcataaagat
    27421 taaaacccaa aaaacaacga cacctaagat aaaattgttc ataggacctg caaaattggt
    27481 aatcagtttg ccccagatag tcgcattttg atattgaaca tctaaaggtg caatccgaac
    27541 ctcagtacca tctgcttcca caaccgttgc atcgtgatcc actgcaaatg ttttttcttc
    27601 ttccagaacc aatcctttga taaagagctt gtcttcaaaa tcaaactggg tcacctgcat
    27661 agggagggct gtttgatcca attttttacc tgagagattg atgcgtttaa ccttaccatc
    27721 atcagcaagt gtcaaactaa caggcgttcc tgtcttgatt tcagttgtat catcacccca
    27781 accggccatg cggacatagc cacccagagg caagattcga atggtatagg ccgttccatc
    27841 cttgccaatg tgagcaaaaa ttttaggtcc cataccgatg gcaaattcac gtactaaaat
    27901 ccctgatttc ttggcaaagt agaagtgccc gaactcgtgc accactacaa taatcccgaa
    27961 aaccagaata aaggttaaaa ttccgagcat agcgtttcct ccgtcttttg attaaaagag
    28021 tccaaataag tgcatgattg gaaatacaag caacatacta tcgaaacgat ccaaaacacc
    28081 accatgtcca gggataaatt tcccagaatc cttaacacca aaatgacgtt tgatcgaact
    28141 ttctagtaaa tcaccaaatt gtccagcaat gctaaagaaa atagcaaaga ctgacatctt
    28201 gtaaattcca tatggaagag caactgtact gtcaactatc ataaagataa tggttactaa
    28261 aattgctcct aaaataccac ccaaggcacc ctcaagggtt ttattaggcg atacccttgg
    28321 tgctaacttt cgtttcccat agttcatccc aacaagatag gcaccactgt ctgtcgccca
    28381 gacgatacac aaggctaaga gagccttgtc caaacctgca acacgagcat ctagtaaagc
    28441 attaaatcca aagcccacgt agaagctcat agcaagaggg aaaaccgcat cctcaatcgt
    28501 ataagacttg ctaaaaacgg tcgttcctaa catgattgaa atcaaaacac tataggcaac
    28561 cacattccca tcaactggca aaaaagtcag gtaattctcc aagggaatgg tcaatgcaaa
    28621 ggttgcaaag agggtcaaga ggccctccat cgtcatggtc tctagacctc tcatcttcaa
    28681 aagttcatgc atggctagca tggctatgat tccgattgct atctgaagca agaggccccc
    28741 aatcattaaa attggtagga aaatagccag ggcaatccct gcaaacaagg ttcttttctg
    28801 taaatcctgg gtcatatttc ctcctaaact cctccaaatc ggcgatgacg acgattatag
    28861 gcaagaatag cttcctgcaa ggccgcttcg tcaaaatcag gccataaggt gtccgtaaaa
    28921 taaagctcac tataggctcc ctgccatgga agaaaattgc tcaaacgtaa ttctccacta
    28981 gtacggataa tcaagtctgg gtctcgtaag tccttaggca aatgctgagt aaagagatag
    29041 ttaccaatca attcctctgt gatgtcacct gggttgattt tggcatctaa aacatcctgg
    29101 gaaatcaact taagcgcctg tgtaatctca gcacgtccac catagttaag agcaaaatta
    29161 agaatcaatc ctgtgttgtt cttagtcaat tcctcagcct tggttaaagc ttcaaaggtt
    29221 tgcttaggca ggcggtctgt ctccccaatc atttgaatct taacattatt cgcatgtagt
    29281 tccgggacat aattatcata aaactctact ggcaagttca tgataaactt gacttcctga
    29341 tctggacggg tccagttttc cgtagaaaaa gcatagaccg taataacctt gacgcccagt
    29401 ttgttggctg ccttggtcac ggtttgcaat gcttccatgc ccgccttatg tccaaaaact
    29461 cgcggttgca tacgtttttt agcccaacgg ccattgccat ccatgatgat gccgatatga
    29521 gcaggaacct gtgtcggaac ctctacttcc acagccttat ctttcttaaa aaatccaaac
    29581 atgatcttat tcctattcaa aaatctatcg tttcattata ccatatttcc ccattttctt
    29641 ctatcactaa gctatttatt ctcaggcacc atgcccattt ttcaaaaaaa taagccgcct
    29701 gattgggcga ctttattttt atagggagat tattatgaaa aagttttagg agtttaagtt
    29761 aaggtcttct taacttatga acttagtgta cactccctag cttaaagttt ccttaagtat
    29821 ttttaaaaat caaatttttc catttctcct gccaattttt cttggataaa cgtgtttgat
    29881 agagttccat tcggtcttca ttttctaaga aatgaggagt tggacgaact tgaaaattca
    29941 aaatatcctc caaaccataa ggtgcataga gttcaaaatc tgattcttca ttcaagcgca
    30001 gtccaactgc cgtacaccgt tctggatact tactcatagc atcacgagaa ctggtatagg
    30061 aagcagtgtg aggactgtgc tgatgcatat agacctgatt tttcaattcc cactggtact
    30121 gaggaaaatc ctctctcagc tttttctcca gtaataaggt ttcctcataa gaaaaatctg
    30181 gatcaaagaa aatcacatct atatctgttt catgatcaaa aggggatttg tctgacaaaa
    30241 gattccagat gaaatttctg acagaacctg ctgccaacta cgagtctttc aaaccaaggt
    30301 ctcggatgat cgtcagaatg gccatcatat ctggattttc tctaaaagcc tctaagattt
    30361 cttgcttatt tttcactgta ttcataacct aagtgctcat atgccttagc agtcgccacc
    30421 cgtccagacc gtgtccgcat gataaaacct ttttgaatca agtaaggctc atacatgtct
    30481 tcaactgtct cacgctcttc ggcgatattg acagaaagag ttcctagacc aacaggtcct
    30541 ccactgtaca tctcaatcat ggtacgaagg attttttgat ccacatagtc caaaccttca
    30601 tggtcaacat ccagcatagt caaagcctta tcggtaataa tatcatcgat taccccattc
    30661 cccattatct gggcaaaatc gcgcacgcgc ttgaggagac gattggcaat acgaggggtt
    30721 ccacgactac gtagggccaa ctcagatgct gcctcatgag tgatttccat ctcaaaaata
    30781 tctgccgtcc gctcgacaat ttctgtcaag tcagcatggg cataatactc catatgacct
    30841 gtaatcccaa aacgtgcccg tagtggattt gagagcatac cagcccgagt cgtcgcacca
    30901 atcaaggtaa aaggaggcaa ctccaaatga acactgcgac tgccttcacc agccccaatc
    30961 ataatatcga tgtagaagtc ctccatggca ctataaagca cttcttccac tgacatgggt
    31021 aagcgatgaa tctcgtcaat aaagaggaca tctccaggct ctaactcatt caaaatcgct
    31081 accaaatcac ccgctttttc gataacagga ccagacgttt gcttgagatt gactcccagt
    31141 tcattggcaa tgacaaaagc catggttgtt ttcccaagcc ctggagggcc aaataagagc
    31201 acatgatcca gcgcttcatc ccgcatttta gcggcttcga taaagatctg aagctgatcc
    31261 ttaaccttat cctgaccaat atattcacgt aaatactgag gacggagcgt gcgttctact
    31321 aactcctcat cacccatcat ctcattatct aaaattctac tcatggctct attatatcaa
    31381 aaaaacaagc cacaaacaaa aaagccacct gattgggtga ctcctaagtt tagcacttat
    31441 gtggtataat attatacggc acttctacac cgcctacgaa aggaggtgag atagcccatg
    31501 atggaattag tactcaaaac tatcatcgga ccaattgtgg tcggtgtcgt tcttcgtata
    31561 gtcgataaat ggctaaacaa ggacaaatag tgtcaaaaaa gacctcaagc ttatttggtc
    31621 gtgagcttgg ggtcttttct agcctatgat atagaactag tactcaattc ctttttatta
    31681 tcccatagtt cacgaatttt gtcaaaggtt tacattttct tcaaccgctg tacgacaaga
    31741 cggttaagat taagagaacg ttagggattc tatcaatttc atagaaattt tgatttcgta
    31801 aacgaagaga caatcttaca tgtcacttct catttaatac gccactacta gacaagcaaa
    31861 atcattatta cagtagttcc agtccttcaa ttaacagtca cttacaatca aattgagttt
    31921 gaactagctg aagcgaccac agacctattt cttagtcata ttcgctaaaa aagtccccgc
    31981 caattccccg accaaaatcc gaaaaatacc gaaaaatatc gaaaaattat ttttagaata
    32041 gtccccaaaa gcctgaaata gagctaaaaa actccacctg attgggtgga gttaagggag
    32101 attattatga aaaagaaaag tttaggattt tattaaataa agttaggagg tctttattta
    32161 ataactacat gatacaagac gaaacttaaa actagcttaa cttttctaaa attttaccat
    32221 tttgcaaaaa atttctatca ccagcacctc accacgcaaa aaagccacct gattgggtgg
    32281 cttcattagg agattgtgat gaaaaaagtt tagga
//
LOCUS       DBERDS010000021        29663 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.021, whole genome shotgun sequence.
ACCESSION   DBERDS010000021 DBERDS010000000
VERSION     DBERDS010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.021"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            366..1529
                     /locus_tag="ACL73E_001112"
     CDS             366..1529
                     /locus_tag="ACL73E_001112"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGS0801092.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGNYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLTMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1526..2203
                     /gene="aroD"
                     /locus_tag="ACL73E_001113"
     CDS             1526..2203
                     /gene="aroD"
                     /locus_tag="ACL73E_001113"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGS0801093.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2193..3047
                     /locus_tag="ACL73E_001114"
     CDS             2193..3047
                     /locus_tag="ACL73E_001114"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGS0801094.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3066..4133
                     /gene="aroB"
                     /locus_tag="ACL73E_001115"
     CDS             3066..4133
                     /gene="aroB"
                     /locus_tag="ACL73E_001115"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGS0801095.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4143..5309
                     /gene="aroC"
                     /locus_tag="ACL73E_001116"
     CDS             4143..5309
                     /gene="aroC"
                     /locus_tag="ACL73E_001116"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGS0801096.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5319..6422
                     /locus_tag="ACL73E_001117"
     CDS             5319..6422
                     /locus_tag="ACL73E_001117"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGS0801097.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            6433..6771
                     /locus_tag="ACL73E_001118"
     CDS             6433..6771
                     /locus_tag="ACL73E_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGS0801098.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6863..8146
                     /gene="aroA"
                     /locus_tag="ACL73E_001119"
     CDS             6863..8146
                     /gene="aroA"
                     /locus_tag="ACL73E_001119"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGS0801099.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8139..8615
                     /locus_tag="ACL73E_001120"
     CDS             8139..8615
                     /locus_tag="ACL73E_001120"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGS0801100.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8612..9460
                     /gene="pheA"
                     /locus_tag="ACL73E_001121"
     CDS             8612..9460
                     /gene="pheA"
                     /locus_tag="ACL73E_001121"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS0801101.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9457..10731
                     /gene="psr"
                     /locus_tag="ACL73E_001122"
     CDS             9457..10731
                     /gene="psr"
                     /locus_tag="ACL73E_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGS0801102.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11010..11855
                     /locus_tag="ACL73E_001123"
     CDS             11010..11855
                     /locus_tag="ACL73E_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGS0801103.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVVFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11845..12948
                     /locus_tag="ACL73E_001124"
     CDS             11845..12948
                     /locus_tag="ACL73E_001124"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGS0801104.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12950..13936
                     /locus_tag="ACL73E_001125"
     CDS             12950..13936
                     /locus_tag="ACL73E_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGS0801105.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13952..15385
                     /locus_tag="ACL73E_001126"
     CDS             13952..15385
                     /locus_tag="ACL73E_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGS0801106.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15414..16448
                     /locus_tag="ACL73E_001127"
     CDS             15414..16448
                     /locus_tag="ACL73E_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGS0801107.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16590..17327
                     /gene="mecA"
                     /locus_tag="ACL73E_001128"
     CDS             16590..17327
                     /gene="mecA"
                     /locus_tag="ACL73E_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGS0801108.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17477..18763
                     /locus_tag="ACL73E_001129"
     CDS             17477..18763
                     /locus_tag="ACL73E_001129"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGS0801109.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18765..19634
                     /gene="thrB"
                     /locus_tag="ACL73E_001130"
     CDS             18765..19634
                     /gene="thrB"
                     /locus_tag="ACL73E_001130"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGS0801110.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGSTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19974..20912
                     /gene="msrB"
                     /locus_tag="ACL73E_001131"
     CDS             19974..20912
                     /gene="msrB"
                     /locus_tag="ACL73E_001131"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGS0801111.1"
                     /translation="MTEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20970..22694
                     /locus_tag="ACL73E_001132"
     CDS             20970..22694
                     /locus_tag="ACL73E_001132"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801112.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLIPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVKLFKGTIRSNLTLGLNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            22696..24444
                     /locus_tag="ACL73E_001133"
     CDS             22696..24444
                     /locus_tag="ACL73E_001133"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801113.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFVKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24746..26005
                     /locus_tag="ACL73E_001134"
     CDS             24746..26005
                     /locus_tag="ACL73E_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGS0801114.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26081..26216
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26255..26755
                     /gene="rplJ"
                     /locus_tag="ACL73E_001135"
     CDS             26255..26755
                     /gene="rplJ"
                     /locus_tag="ACL73E_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGS0801115.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26831..27199
                     /gene="rplL"
                     /locus_tag="ACL73E_001136"
     CDS             26831..27199
                     /gene="rplL"
                     /locus_tag="ACL73E_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGS0801116.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27386..27556
                     /locus_tag="ACL73E_001137"
     CDS             27386..27556
                     /locus_tag="ACL73E_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801117.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            27556..27804
                     /locus_tag="ACL73E_001138"
                     /pseudo
     CDS             27556..27804
                     /locus_tag="ACL73E_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            27818..28158
                     /locus_tag="ACL73E_001139"
                     /pseudo
     CDS             27818..28158
                     /locus_tag="ACL73E_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28151..28531
                     /locus_tag="ACL73E_001140"
     CDS             28151..28531
                     /locus_tag="ACL73E_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGS0801118.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            28544..28777
                     /locus_tag="ACL73E_001141"
                     /pseudo
     CDS             28544..28777
                     /locus_tag="ACL73E_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            28780..29367
                     /locus_tag="ACL73E_001142"
     CDS             28780..29367
                     /locus_tag="ACL73E_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0801119.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            29569..>29663
                     /locus_tag="ACL73E_001143"
     CDS             29569..>29663
                     /locus_tag="ACL73E_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGS0801120.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFST"
BASE COUNT         8830 a         5443 c         6643 g         8747 t
ORIGIN      
        1 ttgagtttgt aacaaaaggc ttctctataa aatcaaattt tccagatatc tactgaagct
       61 gatttatttc ttcatctttc ttctactacc tttgtcacta aatttgacag acacatattg
      121 ctgatacaac ctctctacct ataatctcac agttaacctg aggctagttt catagtttgc
      181 tatttgattt tcgttgataa aaaaaatgct cctccaagac ggaagagcat tttttattgt
      241 gattcttaca catttacttc ctagttttgc aggaagtcta gtataccatt ttttaaaaga
      301 agagtaaaaa agcaagggta gtttcttttt tgagaattgt ctaaaagttt gatataatgg
      361 tagttatgaa tagaataaga gtcagcaaaa gggttgaaaa gaagcttgct aaggggctag
      421 ttttactaga agccagtgat cttgagaatg tcaatcttaa ggatcaggaa gtagaggtgc
      481 agggtcagga aggaaacttt cttgggactg cctacctttc tcagcaaaac aagggcttgg
      541 gctggtttgt cagcaaagac aaggtggcct tcaatcaagc tttctttgaa acgttgttta
      601 gaaaagccaa agaaaagaga agcgcctact atcaagatga tttaacaact acctatcgtc
      661 tctttaatca agagggagat ggctttgggg gtctgacagt ggacctttat ggcaactacg
      721 ccgtcttttc ttggtataac tcttatgttt atcagattcg tcagactata tcagaagcct
      781 ttagacaggt tttccctgag gttttagggg cttatgagaa aatccgcttt aaaggtttgg
      841 actatgaatc tgcccatgtt tatggtcaag aagcacctga ctttttcact gttttagaaa
      901 atggtgtcct gtatcaagtc tttatgaatg atggcttgat gacaggaatt ttcctagacc
      961 agcatgaggt tcgcggtagt ttagttgacg gcttgactat gggtaaatcc ttgctcaata
     1021 tgttttccta cacagcggct ttttcagtag ctgcggccat gggaggagct agccagacaa
     1081 cttctgttga tctagccaaa cgttcacgag aattgtctca agcgcatttt caggcaaatg
     1141 ggctcagcac agacgagcat cgttttatag tcatggatgt ctttgagtat ttcaaatatg
     1201 ccaaacgcaa agacttgacc tacgatgtga ttgtcctaga tccgcctagc tttgctcgga
     1261 ataaaaaaca aactttctct gtggccaagg attatcacaa gttgatttcc cagagtcttg
     1321 agattttaaa tccgggaggg attatcattg ccagtaccaa tgctgccaat gtttcccgtc
     1381 agaaatttac agaacaaatt gataaaggct ttgcaggaag aagttaccag attttaaaca
     1441 aatatggtct tccagcagat tttgcctata ataaaaaaga tgaaagtagt aattacctca
     1501 aggtgattag tatgaaggtt agtaaatgaa attaatcgtt tcagtaatgc caagaagttt
     1561 agaggaggct caggctctgg atgccacgag gtacctggat gccgacatca ttgaatggcg
     1621 tgccgactat ctgcctaaag aagcgatttt gcaggtagct ccagccattt ttgaaaaatt
     1681 cgcaggccgt gagttggttt tcacgctacg aactcgctcc gaaggtggag aaatcgacct
     1741 ttctccagaa gagtatatcc atctaatcaa ggaagttgcg caattctatc aaccagacta
     1801 tattgatttt gagtactata gctacaagga tgtttttgag gaaatgctgg acttcccaaa
     1861 tcttgttttg agttaccata atttccaaga aacacctgag aacatgatgg aaatcttgtc
     1921 agagttgacg atcctaaatc caaaacttgt taaggttgcg gtgatggctc acacggagca
     1981 ggatgtctta gacttgatga actatacacg aggctttaaa accctcaatc ctgaacagga
     2041 atatgtgacc atttctatgg gtaaggtggg caaggtctct cgtatcactg cggatgtgac
     2101 tggttcgagt tggtcttttg ccagtctgga tgaggttagt gcccctgggc agatttctct
     2161 agctagcatg aaaaaaatca gggagatttt ggatgaagct tgatggctat acacgtttag
     2221 ctgcagttgt tgccaatcct attaagcatt ctatttctcc cttcatccac aatagagcct
     2281 ttgaggcgac agctaccaac ggtgcttatg tggcttggga gattgaagcg agtgacttgg
     2341 cagaaacagt ggccaatatt cgtcgctacc agatgtttgg catcaatctg tccatgccct
     2401 ataaggagca ggtgattcct tatttggata agctgagcga tgaagcgcgc ttgattggtg
     2461 cggttaatac ggttgtcaat gagaatggca atttaattgg atataataca gatggcaagg
     2521 gattttttaa gtgcttgcct tcttttacaa tttcaggtaa aaagatgacc ctgctgggtg
     2581 caggtggtgc ggctaaatca atcttggcac aggctatttt ggatggcgtc agtcagattt
     2641 cggtctttgt tcgttccgtt tctatggaaa aaacaagacc ttacctagac aagttacagg
     2701 agcagacagg ttttaaagtg gatttgtgtg ctttagagta tgtttctgaa ctgcaagcaa
     2761 ggattgccga gtcggatttg ctagttaatg ccaccagtgt gggcatggat ggccaatcct
     2821 ctcctgttcc tgaaaacata gtcttaccag aaactctctt agttgcagat atcatatacc
     2881 aaccctttga aacaccgttt ttgaaatggg ctagaagtca gggcaatcca gcagtcaatg
     2941 gtctgggaat gttgctatat caagctgcag aagcttttca actgtggaca ggcaaggaaa
     3001 tgccgacaga agagatttgg cagtctttaa cagaaaaata ccaataaaga aagggagact
     3061 ctcctatgaa aatcagaatc gatattcctc atcatcctta tgatattcag attgaaaaag
     3121 gttgtatggc ccaggctggt cagtggttgc gagaactctg gcaaccgcaa aaggtagtca
     3181 ttgtgacaga taaccatgta gcctctctct atgcagagaa ggtcaagctc agcctagaag
     3241 atgctggttt tcaggtagct gtttttgatt tcttagaagg tgaagaaaga aagaatttaa
     3301 ctactgttca gaaagtctat gaatttctag tcaagcaagg tctgactcgt agcgatggaa
     3361 tcgttgctct tggtggtggc gttgttgggg acctggctgg atttgtagcc tctacctata
     3421 tgcggggtat tcactttgtt cagattccga ctagtttgac agctcaggtt gattcttcta
     3481 tcggtggaaa gacaggcgtt aacacaccat ttgctaaaaa tatggtgggg acctttgccc
     3541 aaccagatgg ggttctgatt gatccacttg ttcttgaaac cctcggaaaa agagagttga
     3601 ttgaagggat gggtgaagtt atcaagtatg gcttgattga ggatccagaa ctgtgggctc
     3661 tcttgacggg gctgaatggt tctgttgaga gcattttgga acatgcagag accttgattg
     3721 aacattcttg tcaggtgaag cgcaagatgg tggttgaaga tgagttggac aatggtattc
     3781 gtctttacct caattttggc cacactattg gccatgccat cgaagcgact gccggttatg
     3841 gcaaggtcat gcatggagag gctgttgcca tgggaatggt acagatttcc aagattgctg
     3901 aggaaaaagg cctcatgcca gctggcatta cccaatctat cacagagatg tgtcagaaat
     3961 tcggcttgcc tgttgactat gaaaattggg aagttgacaa gctttatcag gctcttactc
     4021 atgacaagaa agcgcgtggt aacaccttga aattggtctt ggtgccagag cttggttcag
     4081 cgaccattca tccagtttct ctggaagaga tgaaagacta cttggtaaaa taaggagagt
     4141 gtatgagata tttaactgca ggagaatcac acggcccccg tctaacagct attattgagg
     4201 gaattccagc tggacttcca ttgacagctg aggatatcaa tgaggacctt agacgccgtc
     4261 agggtggcta cggtcgtggt ggtcgtatga agattgagag tgaccaggtt gtctttactt
     4321 cgggcgttcg ccacgggaag acgacagggg cgcctattac tatggatgtc atcaataagg
     4381 accaccagaa atggctggac atcatgtctg cggaggacat tgaagaccgc cttaaaagca
     4441 agcggaaaat tactcatcct cgcccaggtc atgccgattt ggttgggggg attaagtacc
     4501 gttttgatga tttgcgaaat tctttggagc gttcatcagc tcgtgaaacc accatgcggg
     4561 tggcagttgg tgcagtagcc aaacgtctct tggctgagct ggatatggag attgccaacc
     4621 atgtcgtggt ctttggtggc aaggaaatcg atgttcctga aaatctgaca gtcgctgaaa
     4681 ttaagcaaag agctgcccag tctgaagttt ctattgtcaa ccaagaacga gaacaggaaa
     4741 tcaaggacta tattgaccaa atcaaacgtg atggtgatac catcggtggg gttgtggaga
     4801 cagtcgtcgg aggcgttcca gttggtcttg gttcctatgt ccaatgggat agaaaattgg
     4861 atgcaagatt ggctcaagct gttgtctcta tcaatgcctt taaaggggtg gaatttggtc
     4921 ttggctttga ggctggttat cgtaaaggca gccaagttat ggatgaaatt ctctggtcta
     4981 aagaagacgg ttatactcgc cgtaccaata atctaggtgg ttttgaaggt ggtatgacta
     5041 atgggcaacc catcgttgtt cgtggggtta tgaaacccat tcctactctt tataaacctc
     5101 ttatgagtgt ggatatcgaa acccacgaac cttacaaggc aaccgtggag agaagtgatc
     5161 cgactgctct tccagctgca ggaatggtca tggaagcagt tgtagcaacg gttctggcgc
     5221 aagaaatcct cgaaaaattc tcatcagata atcttgagga actaaaagaa gcggtagcca
     5281 aacaccgaga ctatacaaag aactattaag gagttcctat ggcaaaaaca atctatatcg
     5341 caggtcttgg gttgattgga gcctctatgg cacttggtat caaacgcgat catccagatt
     5401 atgaaatttt aggttataat cgtagtcaag cttcgagaga catcgccttg aaagaaggca
     5461 tgattgaccg tgcaacggat gattttgcta gttttgctcc tttggcagat gtcattatcc
     5521 tcagcttgcc aatcaaacaa actattgctt tcattaagga gttggccaat ttggatttgc
     5581 gagaaggcgt tattatttca gatgctggtt cgaccaagtc aaccattgtg gatgcggcgg
     5641 agcagtattt ggctggcaag tctgttcgct ttgtcggggc ccatcccatg gctggtagtc
     5701 acaagacagg ggctgcttcg gcagatgtca atctttttga aaatgcctat tatatcttta
     5761 caccttcaag cctgacaagt caggacacgc ttaaggaaat gaaggatctg ctttcaggtc
     5821 ttcatgctcg ttttatcgag attgatgcca aggagcatga tcgtgtcact tctcagatta
     5881 gccattttcc tcatattttg gcttctagtc tcatggagca gactgcggtc tatgctcaag
     5941 agcatgagat ggcaaggcgc tttgcggcag gtggttttcg agatatgacc cgaattgcgg
     6001 aaagcgagcc aggaatgtgg acctccattc tcttgtccaa tagcgagacc attctggata
     6061 gaattgagga tttcaaggaa cgtttggaag cgattggtca ggccattagt aagggagatg
     6121 aagagcaaat ttggaacttt tttaaccaag cgcgtgaaca acgccagaca atggaaatcc
     6181 ataagcgtgg tggtgtggat agctcttacg acctctatgt tgacgttcct gatgaagaag
     6241 atgtcatcct gcggattttg gaactgctac gtgggacttc cttggttaac atccacatca
     6301 acgaggaaaa tcgtgaggat attcacggaa tcctacaaat ttcatttaaa aatgctcaag
     6361 acttggaaag agccgagcat ctcataacaa aaaataccga ctatacagtc gtcattaaat
     6421 aaggagaaga acatgtcaaa tatttacgat agtgcaaacg aactcagtcg cggtctacgc
     6481 ggattaccag aatacaaggc tgttaaagca gctaaagatg cgattgcagc agatgctgag
     6541 gcaagcaaaa tctttacaga atatcttgcc tttcaagagg aaattcaaaa actagcacag
     6601 acaggtcaaa tgccagatgc gtccttccaa gctaagatgg aaggctttgg taaacagatt
     6661 caaggaaata gcctcttgtc agaattcttt accaagcaac aacaattggc catttacctt
     6721 tctgacattg aaaaaattgt tttcgaacca gtttcagaat tgctgaaata agaaaagaac
     6781 tatcctaaag tcaggaattt ttaaggaatt tctggctttt tatgataaaa taggtaaaag
     6841 tattgcaagt atgaggtcca gtatgaaact aaaaacaaac attcgccatt tacatggtag
     6901 tatccgcgtc ccaggtgaca agtctatcag ccaccgttcc attatctttg gaagtttggc
     6961 tgagggtgag accaaggttt atgatattct gcgaggtgaa gacgttcttt cgaccatgca
     7021 ggtttttcgt gaccttggtg ttgaaattga ggataaagat ggggttatta ccgttcaagg
     7081 tgtaggcatg gctggcttaa aagcgccgca aaatgccctt aatatgggaa attctggcac
     7141 ctcgattcgc ctgatttcag gtgtccttgc tggtgcagat ttcgaagtag agatgtttgg
     7201 agatgatagt ctttccaaac gtcctatgga ccgtgtgacc cttccactga aaaaaatggg
     7261 cgtcagcatc tcagggcaaa ctgaacgaga cttgcctccc cttcgcttaa aagggacgaa
     7321 aaacctaaga cctattcatt atgagttgcc aattgcctct gcccaagtca agtcagcctt
     7381 gatgtttgca gccttacaag ctaaggggga gtcagttatt atcgaaaaag agtacacccg
     7441 taatcatact gaagatatgt tgcaacaatt tggtggtcat ttaagtgtgg atggtaagaa
     7501 aatcacagtc caagggccac aaaaattgac gggacagaag gtggtcgtac caggagatat
     7561 ttccagtgca gccttttggt tagtcgcagg tttgattgct ccaaattctc gtctagtgct
     7621 gcagaatgtg gggataaacg aaactcgcac cggtattatt gatgtcattc gtgccatggg
     7681 tggaaaattg gaaataactg aaatcgatcc agtcgctaaa tctgcaacct tgattgttga
     7741 gtcttctgac ttgaaaggaa cagagatttg tggcgctttg attccacgtt tgattgatga
     7801 attgcctatt attgccctac ttgcgaccca agcccaaggt gtaacagtta tcaaggatgc
     7861 tgaggagctc aaggtcaagg aaacagaccg tattcaggtt gtggcagacg ccttaaatag
     7921 tatgggagca gatattactc ctacggcaga tgggatgatt atcaaaggaa aatcagctct
     7981 tcacggtgct agagtcaata cgtttggtga ccaccgtatc ggcatgatga cagctatcgc
     8041 agccctattg gttgcagatg gagaggtgga gcttgaccgt gcagaagcca tcaataccag
     8101 ctatcctagt ttctttgatg atttggagag cttgattcat ggctaaggtg ttattagggt
     8161 ttatgggggc tggaaaatcg actattgcaa gaggcttgga ccctaattac cttgatatgg
     8221 atgctctgat tgagaagcgc ctaggtatgt ccattgcgaa ttttttcgct gaaaagggag
     8281 aagcagcctt tcgtcaggta gaatcagaag tcctagctga tttattacaa agagaccaag
     8341 tcgtgtcaac tggaggagga gtggttattt ctcagagaaa tcgtgactta ctcaagacta
     8401 atacagataa catctacctg aaagcagatt ttgaaaccct ctacctacgt atcgcagctg
     8461 ataaggacaa tcagcgaccg ctttttctaa ataatagcaa ggaagaacta gtagctattt
     8521 ttcaagaaag acaggcttgg tatgaggaag tggctagtcg ggttttggat gtgaccaagc
     8581 taagcccaga ggaaattata gaggaactaa gatgaaaatt gcttatctag gtcccaaagg
     8641 atcattttca caccacgttg tgcagacagc ttttcctcat gaggaattgc aggcttttgc
     8701 caacattaca gatgtcatca aggcttatga gcaaggatta gtggactatt ctgtggtgcc
     8761 agttgaaaat tctattgagg gtagtgttca tgaaaccttg gactatcttt ttcatcaggc
     8821 tcacatccaa gcagtagcag aaatcgttca gcctattcat cagcagttga tggtggttcc
     8881 aggccatact aagattgaaa agattttttc acatccacag gccttggctc aaggaaagaa
     8941 attcatcgat gaacaatatc cagaggctca aatcgaggta acagctagta cagcttatgc
     9001 ggcccgtttt atttccgaac atccagatca gccctttgca gcaattgcac ctagaagttc
     9061 tgctgaagaa tatggattgg aactgattgc cgaggatatt caggaaatgg aagccaattt
     9121 cacacgtttc tggcttctag gagctgaaaa gcctagtatt cccttgcaag cacaaactga
     9181 aaagatgagt ttggccttga cattacctga caaccttcca ggtgcacttt ataaggccct
     9241 gtcgaccttt gcttggcgag gaattgactt gacaaaaatt gaaagtcgtc cactcaagac
     9301 agcactgggt gaatactttt tcattatcga tgtggattat accgataagg acttggtcca
     9361 ctttgcccaa aaagaattag aagcgattgg aatccagtat aaaattctgg gtgcctatcc
     9421 tatttatcca atatcagacc atggaaagga gagaagatga gtaaagaaaa tcccttaagt
     9481 catcatgagc agttgcgtta tgattatttg ctaaaaaata ttcactatct caatgagaga
     9541 gaaaaaaatg agtttgtcta tttgcaagaa aagctaactc ttgctagggg aaatagtagc
     9601 tctagcttgg aacaagaaag agaagagcag gttgacttac caagctatgc gaaccggagt
     9661 cgctcacaat ccaaatcaca agcactctct ttccctccaa aaaagaaaag acggaagctc
     9721 cgtcttaaac gaatttttat ggtgattttt tcacttttgg tctgtgtggc tttggccatg
     9781 gtattcatgt ttttgcgtgg ttaccaagat gctagcgcaa agaaaactgc tgatgcccgg
     9841 gcagctcaag tagaagtctt taatggtcag gacactagag atggagttaa tattttaatc
     9901 atgggtactg atggtcgaat cggccagaac agtgttgaga cacgaactga ctctattatg
     9961 gtattaaatg tcgggggctc agataagaaa atgaagctag tcagtttcat gcgtgataat
    10021 ttggtctata tagatggtta tagtcaagtg attaacggta gaaaacagac agataacaag
    10081 ttaaacgtag cctacgagtt aggagaacaa gaagggcaaa aaggggcaga aatggttcgc
    10141 caagtcttga aagataattt tgacttggac attaagtact acgccttggt tgatttccag
    10201 gcctttgcca cagcgattga cacgcttttc cctgatgggg tgacgattga tgctcaattt
    10261 tcaacattga atgggcgtcc cctaacagaa gctacagtcg gagatgattt atacgctacc
    10321 gagactgagt ctccaaccca aaccattaaa gtcggaaaac agcagatgaa tggctcgacc
    10381 ctgctcaatt atgctcgttt ccgtgatgat gatgaggcgg attacggccg tacaaaaaga
    10441 cagcaacaag ttttaacagc aattttagag caaattaaag atcccactaa acttttcact
    10501 ggttctgaag ctcttggaaa ggtttttgct atgacctcaa ccaacgtacc ctatactttc
    10561 ctcctaacaa acggtttatc tgttttggat ggagcaaaaa atggtattga aaaattgacg
    10621 attccagaac tgggtgactg ggtagatgcc tatgatgttt atggaggctt gggcttgctg
    10681 gttgatcaaa acaaatatca aaccaagctc gctcaaatgg gcttgagata agataatact
    10741 caatgaaaat caaagtgcaa attaggaagc tagccgcagg ctgctaaaaa cacagttttg
    10801 aggttgtaga taagactgac gaagtcagtt acctatacct acggcaaggt gaagctgacg
    10861 ttgtttgaag agattttcga agagtataag acagaaaaat caaagtttga tagctatttg
    10921 gatagcagtc aggctttgat tttttacagt ctgcaataga ttttcacccc ttgtttgtgg
    10981 tataatgaaa cgatacgata gaaagaataa tgaacaatat gactgattta aaagcaattc
    11041 aggctcgtag tctggagatg gctgaatatt ttgtggtctt ttgtaaagaa catgatttgc
    11101 tctgttatct ctgtggcgga ggcgctattg gtgcccttcg aaacaaggga tttattcctt
    11161 gggacgacga cctagacttt tttatgcctc gtaaagatta tgagaaatta gcagaattat
    11221 ggcctcgtta tgcagatgaa cgttatttct tgtcaaagag tcacaagaat tttgttgatc
    11281 gtaatctttt tattaccatt cgtgacaagg aaaccacctg tatcaagcct tatcagcagg
    11341 atttggattt gccacatggt ctggccttgg atgttttgcc tttggattat tatccgaaaa
    11401 atccagctga gcggaaaaaa caggttcgtt gggccttgat ttattcactc ttttgtgcgc
    11461 aaactattcc agaaaagcat ggtgctctca tgaaatgggg aagtcgcatt ttactgggtt
    11521 tgactccaaa atctctccgt tatcgcatct ggaaaaaagc tgagaaagaa atgactaagt
    11581 atgatttggc tgattgtgat ggcattacag aattatgctc aggtcctggc tacatgagaa
    11641 acaagtaccc aatcacatct tttgaagaca atcttttctt gccatttgaa ggaacagaga
    11701 tgcctattcc aatcggctat gatgtctatc tcagaactgc ttttggggat tatatgacgc
    11761 ctccaccagc agacaagcag gtaccgcatc atgatgctgt catcgctgat atggataagt
    11821 cttatacaga atacaaggga gaatatggtg gctaagaaaa aaatcttatt ttttatgtgg
    11881 tctttttctc ttggaggtgg tgcagagaag attctatcaa ccattgtttc aaatctggat
    11941 ccagaaaagt atgatattga tattcttgaa atggagcact ttgacaaggg atatgaatct
    12001 gttccaaagc atgtacgcat tttaaaatcc cttcaagatt atcgccaaac cagatggtta
    12061 cgagcttttt tgtggagaat gagaatttat tttccaagac tgactcgtcg tttgcttgta
    12121 aaagatgatt atgatgttga agtttctttt accattatga atccaccact gttgttctct
    12181 aaaagaagag aagtcaagaa gatatcttgg attcatggaa gtattgaaga acttcttaag
    12241 gatagctcta aaagagaatc acatagaagc cagttggatg ctgcgaatac aattgtaggg
    12301 atttcaaaaa agaccagcaa ttctatcaag gaagtttatc cagattatgc ttctaaatta
    12361 cagacaatct acaatggata tgattttcag actattctag aaaaatctca agagaagatc
    12421 gatatcgaga ttgctcctca aagtatctgt actatcggac ggattgagga aaataagggt
    12481 tctgaccgtg tagtggaagt gatacgatta ttacaccaag agggaaaaaa ctatcatctc
    12541 tattttatcg gggctggtga tatggaagag gaactgaaaa aacgagtcaa agagtatgag
    12601 attgaggact atgtacattt ccttggttat caaaaaaatc cttatcagta tttatctcag
    12661 acgaaagttc tcttgtctat gtctaaacaa gaaggctttc ctggagtgta tgtggaggcc
    12721 ttgagtctgg gactcccttt tatctctacg gacgttggag gggctgagga attatcccaa
    12781 gaaggacgat ttggacaaat cattgagagc aatcaagagg cagctcaggc gattactaat
    12841 tacatgactt ctgcctcaaa ctttaatgtc gatgaggcta gccaattcat tcaacaattt
    12901 acaattacaa aacaaatcga acaagtagaa aaactattag aggagtagca tggaaactgc
    12961 attaattagt gtgattgtgc cagtctataa tgtggcgcag tacctagaaa aatcgatagc
    13021 ttccattcag aagcagacct atcaaaatct ggaaattatt cttgttgatg atggtgcaac
    13081 agatgaaagt ggtcgcttgt gtgattcaat cgctgaacaa gatgacaggg tgtcagtgct
    13141 tcataaaaag aacgaaggat tgtcgcaagc acgaaatgat gggatgaagc aggctcacgg
    13201 ggattatctg atttttattg actcagatga ttatatccat ccagaaatga ttcagagctt
    13261 atatgagcaa ttagttcaag aagatgcgga tgtttcaagc tgtggtgtca tgaatgtcta
    13321 tgctaatgat gaaagcccac agtcagccaa tcaggatgac tattttgtct gtgattctca
    13381 aacatttcta aaggaatacc tcataggtga aaaaatacct gggacgattt gcaataagct
    13441 aatcaagaga caaattgcaa ctgccctatc ctttcctaag gggttgattt acgaagatgc
    13501 ctattaccat tttgatttaa tcaagttggc caagaagtat gtggttaata ctaaacccta
    13561 ttattactat ttccatagag gggatagtat tacgaccaaa ccctatgcaa agaaggattt
    13621 agcctatatt gatatctacc aaaagtttta taatgaagtt gtgaaaaact atcctgactt
    13681 gaaagaggtc gcttttttca gattggccta tgctcacttc tttattctgg ataagatgtt
    13741 gctagatgat cagtataaac agtttgaagc ctattctcag attcatcgtt ttttaaaagg
    13801 ctatgctttt gctatttcta ggaatccaat tttccgtaag gggagaagaa ttagtgcttt
    13861 ggccctattc ataaatattt ccttataccg attcttatta ctgaaaaata ttgaaaaatc
    13921 taaaaaatta cattagaacg ggggtgacca agtgattgat gggaaacgat tattatttag
    13981 tttgaccata gtcagttata ccttgacgct agtaagtgga attgtgtatc tgtttaataa
    14041 taataatgtt agcttacttt ctactttatt gttcttgttg gttagtagct taattgcttg
    14101 ttggaatgat atcaagtatt acttaatcca ttttattttc tatttaacca tttttgtatt
    14161 tctggtatca agaccgacca ttgattattt tagggatggt gctttggata cctatcatcc
    14221 aatagcctat cgttttgcct ttatagttgt catggtttcg attctgggct tgaccacagg
    14281 aggcgtcctg gctcgttact tcatagctag gaagaaaata aaagtagcaa atataggaaa
    14341 ttctctaaaa gaggtttata tcaagcggtt acgctttgta tcactaggag tttttcttct
    14401 aacttatcct ttctatttca ttcggttatt tgaacggctc ttgtatcgtt tgcagacttc
    14461 ctactatgcc tactatgcaa attttgaaag taaactgcct tattttacct acattttgtc
    14521 tacctttacg gtctatgcaa tgtgtatgta tctggcaacc aagccaaaga aattgcaggc
    14581 cacagcagtg cttgtctcct ttattgcagc taatactatt catttggcaa ttgggacacg
    14641 aaatcccttt attttaagta ttttatttgc ttttgtttat tactttatgc gggagcaaac
    14701 tgaaaaagga aaatggattg ggtttaaaga aaagttagcg atttttgtag gttctcctat
    14761 tctcatgtta gcgatgggag tactcaatta tgtacgggat aatgtccaag tttcccatac
    14821 aggtttctgg gatatcttac ttgactttat ctataaacaa gggactagtt ttggtgttct
    14881 ggctcgaggt tttctattta acagtagcct cccttaccga gatttccgta attttacttt
    14941 tggtcctgtt cttgattatt ttgcaagggg gagtttggga gccattttcg gaggaaaagc
    15001 ctttgaacat acaaccaata gtgtggaact agctattgat agtaatagtt atgcccacaa
    15061 tctatcctat cttgtcttga acaaggaata cttgaaaggg catggtatcg gaagtagtta
    15121 tatcatggag ttgtataccg actatggtat gattggagtc tttctgctta gtttcttact
    15181 cggcgtatta tttatagcca tgctgcaagt agcctatcgc tcaaggacaa tcctatttgc
    15241 tttatcccta ctcatcttga ataatctatt ctttatgcca agaagcagct tttcagaaag
    15301 tttcttcaat ttatttacaa tgcaattctg gggaattgtt cttgtgatta tatttgtagc
    15361 aaaaatgctt acaaaggaaa actagtatct actaaacaaa ggagaaaaaa atcatgtttg
    15421 aacattattc agtagctgat ttgtttgcaa atctttataa aaagcgaaaa gcaaatattt
    15481 tagctctcat cgctttattt gctctcattg ctgtaccatt tacaattaaa gcagttagga
    15541 ataaaaatac tgtcaaagat acaacaagtt attcaactta tcttatctat aaaatcactc
    15601 ctccaaaaga gtcggccaaa acgattttga atcatcaaat tggtggttat agtgattttt
    15661 atgggaaatt gattgatggt aatttgaatg gagcttatct tttcaatgat gtagaaccca
    15721 gtgagttgaa aaaaattgcc agtgaattag acacgacaga aacaaccttg aaaaattcaa
    15781 cgaatgacta ttggtggaaa aaattgaccg tctactatat gattgacgat gcaggggttg
    15841 gtgtgaaaat tttgacatca agtaaagatg ccaatgactt gttagagaaa aaaattgatg
    15901 ggttgattga gaaatttaaa catgcttatg caaatgtgaa aattgaaaaa ctggaaacca
    15961 tcaactctaa agaattgaac gcaaatggtg aaacagcgct tggcttaaat gtgaaaaatc
    16021 tgattcttcg tttagttgtt attggagtgg tttgtgtgat tttggttgtg atgggaaatg
    16081 tgttagttta tctctttaat ccaacaatca atagagtagg tgatttttct cagtatcaaa
    16141 ttgattttgt aacagagatt acaacaattg ctaacctagc agatgttttg tcatacaaaa
    16201 atactggaca ggaattgacc atcgttagct caaataaagc tatcctagat aaattgaaac
    16261 agagtcaaga agctttaaaa ggaatgcatt ttgtagattt acaggatgta tcatctcttt
    16321 tggaaagaga tacagtcctt cttgttgaag agtacggagt gactcgttat aagaaatttg
    16381 agcaaagtct tcaaattctc agaaacttaa atcgttctat cctcggtgta gcaaccttta
    16441 aattataagt attctgatgt ataaggtctt caaagtcggc taagagccga ttttgaaggc
    16501 tttttctatc tgtctgcaga aattttcttt tgataaaatc gtaaaaatct agtataatag
    16561 atagaactga aagtatgagg ttactagcaa tgaaaatgaa acaaattagt gatacaactt
    16621 taaaaatcac gatgtcttta gaggatttga tggatcgtgg aatggagatt gctgactttc
    16681 tcgttcctca agaaaaaaca gaagagttct tttatgctat cttggatgag ctagagatgc
    16741 ctgatagctt tctggataca ggcatgttga gcttccgtgt gactccaaaa cctgataagg
    16801 tagatgtctt tgtgaccaag tcaaagattg accaaaatct agattttgaa gacttatcgg
    16861 atttgccaga tatggaagaa ttggctcaaa tgtctccaga tgaatttatc aaaaccctgg
    16921 aaaaaagcat cgcagacaaa accaaggatg atatcgaagc cattcaatct cttgagcaag
    16981 ttgaagccaa ggaagaagag caagagcagg ctgaacaaga agctgagagt aagaaagaac
    17041 cttacatcta ctacatcctt tcttttgcta agttggctga cttggtagct tttgccaaga
    17101 cagtgacttt tgaaatggaa acttctgaac tctacaaaat gaacgagcgc tattatttga
    17161 ccattttagt ggatattgaa aatcatccaa gcccatatcc agcttggctg ttggcccgta
    17221 tgcgcgagtt tgcagaggat agtgatatca gtcgctcagt cttacaagag tatggtcaag
    17281 tcttgatgag tcacgatgca gtgctcaatc tgcaaaaaat cggctaatcc tttctggaaa
    17341 gctatttcag attttaagaa gagcgaatcg tctgattcgt tttttctttt tatactgaaa
    17401 tagtgattta ctataatagg aattttcaca aaattctgtt ataatggcta tattagaaaa
    17461 tttcgaggag ataaagatga cagttaaaat tgctttacta ggatttggta ccgttgcaag
    17521 tggtgtgcct ttcctcctaa aggaaaatgg aggaaaaatc aatcaatcag cacattcaga
    17581 tatcaaagtt gctaaggtat tggtcaagga tgaagatgaa aaaaatcgct tgcttgcagc
    17641 agggaatgac tttaactttg taaccaatgt ggatgatatt ttatcagacc aggatattac
    17701 tatcgtagtg gaattgatgg ggcgtattga gcctgctaaa acctttatca ctcgtgcctt
    17761 ggaagctgga aaacacgttg ttactgctaa caaggacctt ttagctgtcc atggcgcaga
    17821 attgctagaa atcgctcaag ctaacaaggt agcactttac tacgaagcag cagttgctgg
    17881 tgggattcca attcttcgta ctttagcaaa ttccttggct tctgataaaa ttacgcgcgt
    17941 gcttggagta gtcaacggaa cttccaactt catggtgacc aagatggtgg aagaaggctg
    18001 gtcttacgat gatgctcttg cggaagcaca acgtctagga tttgcagaaa gcgatccgac
    18061 gaatgacgta gatgggattg atgcagccta caagatggtt attttgagcc aatttgcctt
    18121 tggcatgaag attgcctttg atgatgtagc ccacaaggga atccgcaata tcacaccaga
    18181 agacgtagct gtagctcaag agcttggtta cgtagtgaaa ttggttggtt ctattgagga
    18241 aacttcttca ggtattgctg cagaagtgac tccaaccttc ctacctaaag cgcacccact
    18301 tgctagtgtg aatggcgtaa tgaacgctgt ctttgtagaa tctatcggta ttggtgagtc
    18361 tatgtactac ggaccaggtg cgggtcaaaa accaactgca acaagtgttg tagctgatat
    18421 tgtccgtatc gttcgtcgtt tgaatgatgg tactattggc aaagacttca acgaatatag
    18481 ccgtgacttg gtcttggcaa atcctgaaga tgtcaaagca aactactatt tctcaatctt
    18541 ggctctagac tcaaaaggtc aggtcttgaa gttggctgaa atcttcaatg ctcaagatat
    18601 ttcctttaag caaatccttc aagatggcaa agagggtgac aaggcgcgtg tcgttatcat
    18661 cacacacaag attaataaag cccagcttga aaatgtctca gctgaattga agaaggtttc
    18721 agaattcgac ctcttgaata ccttcaaggt gctaggagaa taagatgaag attattgtac
    18781 ctgcaaccag tgccaatatc gggccaggtt ttgactcggt cggtgtagct gtaaccaagt
    18841 atcttcaaat tgaggtctgc gaagaacgag atgagtggct gattgaacac cagattggca
    18901 aatggattcc acatgatgag cgtaatctct tgctcaaaat cgctttgcaa attgtaccag
    18961 acttgcaacc aagacgcttg aaaatgacca gtgatgtccc tttggcgcgc ggtttgggtt
    19021 cttccagctc ggttatcgtt gctgggattg aactagccaa ccaactgggt caactcaact
    19081 tatcagacca tgaaaaattg cagttagcga ccaagattga agggcatcct gacaatgtgg
    19141 ctccagccat ttatggtaat ctcgttattg caagttctgt tgaagggcaa gtctctgcta
    19201 tcgtagcaga ctttccagag tgtgattttc tagcttacat tccaaactat gaattacgta
    19261 ctcgcgacag ccgtagtgtc ttgcctaaaa aattgtctta taaggaagct gttgctgcaa
    19321 gttctatcgc caatgtagcg gttgctgcct tgttggcagg agacatggtg accgctgggc
    19381 aagcaatcga gggagacctc ttccatgagc gctatcgtca ggacttggta agagaatttg
    19441 cgatgattaa gcaagtgacc aaagaaaatg gggcctatgc aacctacctt tctggtgctg
    19501 ggtcgacagt tatggttctg gcttctcatg acaagatgcc aacaattaag gcagaattgg
    19561 aaaagcaacc tttcaaagga aaactgcatg acttgagagt tgatacccaa ggtgtccgtg
    19621 tagaagcaaa ataaagaata gaagatagga tggggaaact cttgaccaga gggtttcata
    19681 tcctttttgt gaaaagaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    19741 ccgcaggctg ctcaaaacag tgttttgagg ttgtggatag aactgacgac gtcagctcaa
    19801 gacactgttt tgaggttgca gatagaactg acgacgtcag ctcaagacac tgttttgagg
    19861 ttgcagatag aactgacgac gtcagtaaca tatatacggt aaggtgacgc tgacgtggtt
    19921 tgaagagatt ttcgaagagt attagttaaa aacgtgataa aggagaaata aaaatgacag
    19981 aaatttatct agcaggtggt tgtttttggg gcctagagga atatttttca cgcatttctg
    20041 gagtgctaga aaccagtgtt ggctacgcta atggtcaagt cgaaacgacc aattaccagt
    20101 tgctcaagga aacagaccat gcagaaacgg tccaagtgat ttacgatgag aaggaagtgt
    20161 cactcagaga gattttactt tattatttcc gagttatcga tcctctatct atcaatcaac
    20221 aagggaatga ccgtggtcgc caatatcgaa ctgggattta ttatcaggat gaagcagatt
    20281 tgccagctat ctacacagtg gtgcaggagc aggaacgcat gctgggtcga aagattgcag
    20341 tagaagtgga gcaattacgc cactacattc tggctgaaga ctaccaccaa gactatctca
    20401 ggaagaatcc ttcaggttac tgtcatatcg atgtgaccga tgctgataag ccattgattg
    20461 atgcagcaaa ctatgaaaag cctagtcaag aggtgttgaa ggccagtcta tctgaagagt
    20521 cttatcgtgt cacacaagaa gctgctacag aggctccatt taccaatgcc tatgaccaaa
    20581 cctttgaaga ggggatttat gtagatatta cgacaggtga gccactcttt tttgccaagg
    20641 ataagtttgc ttcaggttgt ggttggccaa gttttagccg tccgatttcc aaagagttga
    20701 ttcattatta caaggatctg agccatggaa tggagcgaat tgaagttcgt tctcgttcag
    20761 gcagtgctca cttgggtcat gttttcacag atggaccgcg ggagttaggc ggcctccgtt
    20821 actgtatcaa ttctgcttct ttacgctttg tggccaagga tgagatggaa aaagcaggat
    20881 atggctatct attgccttac ttaaacaaat aaaacagaga gtggggcttc ccactttctt
    20941 catttctaga atatgaatag aagggattta tgaaacacct attatcttac ttcaaaccct
    21001 acatcaagga atcaatttta gcccccttgt tcaagctgtt agaagctgtt tttgagctct
    21061 tggttcccat ggtgattgct gggattgttg accaatcttt acctcaggga gatcaaggtc
    21121 atctctggat gcagattggc ctgctcctta tctttgcagt aattggcgtt ttagtggcct
    21181 tgatagctca attttactca gcaaaggcag cagtaggttt tgctaaggaa ttgacaaacg
    21241 atctttatcg tcatattctt tccttgccca aggacagcag agaccgtctg acaacttcta
    21301 gtttggttac tcgcttgact tcggatacct accagattca gactggtatc aatcaattcc
    21361 tgcgtctctt tttacgagcg cccattatcg tttttggtgc catttttatg gcttatcgaa
    21421 tctcagctga gttgactttc tggttcttag tcatggttgc cattttgacc attgtcattg
    21481 tagggttatc tcgattggtc aatcctctct acagtagtct cagaaagaaa acggaccaac
    21541 tggttcagga aacgcgccag caattgcaag ggatgcgggt tattcgtgct tttggtcaag
    21601 aaaaacgaga gttacagatt tttcaaaccc ttaaccaagt ttatgctaga ttacaagaaa
    21661 agacaggttt cttgtctagt ttattaatac ctctgaccta tctgattgtc aatggaactc
    21721 ttctcgttat tatctggcaa ggctatattt caattcaagg aggagtactc agtcaaggtg
    21781 ctctcattgc tcttatcaat tacctcttac agattttggt ggaattggtc aagctagcca
    21841 tgctgatcaa ttccctcaac cagtcctata tctcagccaa gagaatcgag gaggtctttg
    21901 cggaatctcc cgaaaacatc cattcagaat tagaacaaaa gcaagttacc agtggtcggg
    21961 ttttacaagt ccaagaattg acttttacct atcctgatgc ggcccagcct tctctgagag
    22021 acatttcctt tgatatgact caaggacaaa tccttggtat cattgggggg actggttctg
    22081 gtaaatcaag cttggtgcaa ctcttacttg gactttatcc agtagacaag gggaacattg
    22141 acctttatca aaatggacgt agtcctctta atttggagca gtggcggtct tggattgcct
    22201 atgtacctca aaaggtcaaa ctctttaagg gaactattcg ttccaacttg actttaggtt
    22261 taaatcaaga agtatctgac cagaaactct ggcaggcctt ggagattgcg caagctaagg
    22321 attttgtcag tgaaaaggaa ggacttttgg atgccctagt tgaggcaggg gggcgaaatt
    22381 tctcaggtgg acaaaaacaa aggttgtcta tcgcccgagc agtcttgcgc caagctccgt
    22441 ttatcatcct agatgatgca acctcggcac tggataccat tacagagtcc aagctcttga
    22501 aagctattag agaaaatttt ccaaacacga gcttaatttt gatctctcaa cgaacctcga
    22561 ctttacaaat ggcggaccag attctcctct tggaaaaagg tgagttgcta gctgttggca
    22621 agcacgatga cttgatgaaa tccagccaag tctatcgtga aatcaatgca tcccaacatg
    22681 gaaaggagga ctagaatgaa acgacaaact gtaaaccaga cgctcaaacg tttagccgta
    22741 gatttagcaa accatccctt cctccttttc ctagcctttc taggaactat tgcccaagtt
    22801 ggcttatcaa tttacctacc tattctgatt gggcaggtca ttgaccaagt cctagtggct
    22861 ggttcatcac cagttttttg gcagattttt ctccagatgc tcttggtggt aataggaaat
    22921 actctggtac aatgggccaa tcctctcctc tataatcgtc taatcttctc ttataccaga
    22981 gatttacggg agcgaatcat ccataaactc catcggttac cgattgcctt tgtagatagg
    23041 caaggtagtg gagagatggt tagtcgtgta accacggaca tcgaacagtt ggcagctggc
    23101 ttgaccatga tttttaacca atttttcatt ggtgttttga tgattttggt tagtattcta
    23161 gccatgctcc aaattcatct cctcatgact ctcttagtct tgctgttgac gccactgtcc
    23221 atggtgattt cacgctttat tgccaagaga tcctatcatc tcttccagaa gcaaacagag
    23281 acgaggggaa ttcagactca gttgattgaa gaatcgctta gccagcagac tataatccag
    23341 tccttcaatg ctcaaacaga atttatccaa agattgcgtg aggctcatga caactactca
    23401 ggctattctc agtcagccat cttttattct tcaacggtca atccttcgac tcgctttgta
    23461 aatgcactca tttatgccct tttagctgga gtaggagctt atcgtatcat gatgggttca
    23521 accttgaccg tcggtcgttt agtgactttt ttgaactatg ttcagcaata caccaagccc
    23581 tttaatgata tttcttcagt gctagctgag ttgcaaagtg ctctggcttg cgtagagcgt
    23641 atctatggag tcttagatag ccctgaagtg gctgaaacag gtaaggaagt cttgaccagt
    23701 gaccaagtta agggagctat ttcctttaaa catgtctctt ttggctacca tcctgaaaaa
    23761 attttgatta aggacttgtc tatcgatatt ccagctggta gtaaggtagc catcgttggt
    23821 ccgacaggtg ctggaaaatc aactcttatc aatctcctta tgcgttttta tcccattagc
    23881 tcgggagata tcttgctgga tgggcaatcc atttatgatt atacacgagc atcattgaga
    23941 cagcagtttg gcatggtgct tcaagaaacc tggctcacac aagggaccat tcatgataat
    24001 attgcctttg gcaatcctga agccagtcga gagcaagtaa ttgctgctgc caaagcagct
    24061 aatgcagact ttttcatcca acagttgcca cagggatacg ataccaagtt ggaaaatgct
    24121 ggagaatctc tctctgtcgg ccaagctcag ctcttgacca tagcccgagt ctttctggct
    24181 attccaaaga ttcttatctt agacgaggca acttcttcca ttgatacacg gacagaagtg
    24241 ctggtacagg atgcctttgt aaaactcatg aagggccgca caagtttcat cattgctcac
    24301 cgtttgtcaa ccattcagga tgcggattta attcttgtct tagtagatgg tgatattgtt
    24361 gaatatggta accatcaaga actcatggat agaaagggta agtattacca aatgcaaaaa
    24421 gctgcggctt ttagttctga ataagccatt ctcttttgaa agtttatgga cgaaaaaagt
    24481 tgccttcgag tgactttttt gttacaatag ctagaaaaat tgttcactgt aatactcaat
    24541 gaaaatcaaa gagcaaacta ggaagctagc cgtaggttgc tcaaaacact gttttgaggt
    24601 tgcagataga actgacgaag tcagctcaaa acactgtttt gaggttacag atagaactga
    24661 cgaagtcagt aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac
    24721 ttgtctttta gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg
    24781 tgatcaagat ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt
    24841 ctatgtcggt caagataagc cagcgttttt agagcaagct gagcagatta tagactatca
    24901 gggagcttgg attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct
    24961 gagagggatc cgagatgaca gcaatctcca tgaatggctc aatgactata tttggccagc
    25021 agaatctgag tttactcccg acatgactac caatgcggtc aaagaagccc tgacagagat
    25081 gctccagtca ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca
    25141 gcaaatttat caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt
    25201 ttcttcagag acagaaacaa ctgctgagac tataagtaga actcgatcca tcatagacga
    25261 aatcttaaaa tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag
    25321 ctgcagtaga gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct
    25381 ccatgtccat gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa
    25441 acgccccctt gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca
    25501 cggggtcgaa ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc
    25561 ccacaatcct atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca
    25621 aaaagcggga gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga
    25681 tatgtttgag gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag
    25741 ccagtttcca atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg
    25801 aatggaaaat cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca
    25861 accacaaggg aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc
    25921 agttaaatct agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg
    25981 tcaagtcctg acagtagaac tttaaaagaa aaattacgaa aaattttaaa aaaagtttgc
    26041 aaaaatcttg cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc
    26101 taagacagta ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa
    26161 aaagaagcgt attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc
    26221 cccaagcaaa ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa
    26281 agcggaacta gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt
    26341 agacgctcgt ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag
    26401 cgaagttgag tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg
    26461 tcttgaagat cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga
    26521 tgttatcgca ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat
    26581 taaaggtggt gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac
    26641 tcttccaaac cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg
    26701 caacgttgct cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta
    26761 agctacacag cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga
    26821 ggaaataaca atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat
    26881 ccttgaattg aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc
    26941 tcctgtagct gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga
    27001 cgttgaattg acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat
    27061 cactggtctt ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa
    27121 agaaggcgtt gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc
    27181 ttcagttact cttaaataat agagtatcgc aatttgattg cggaatccct atttaccagt
    27241 ctttgagagc gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa
    27301 ttctttggca ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc
    27361 ctttttttgt gtttcggagg taattatgca aaaggaagga cagtcatcac gtcaattcgt
    27421 gaagagtcat ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga
    27481 tgaaatggaa caagtaggtt taatccgatt tgatgaattt ggaaatgttg gaattttagt
    27541 cttggaggga caataatgaa gcgtattacc gctaatcaat atcagacatc agagcgttat
    27601 tataagctcc ccaaactttt atttgagagt gaacggtata agaatatgaa actggaggtt
    27661 aaggtggttt actcagtttt aaaagatcgg ttggagttgt ctttgagcaa aggttggatt
    27721 gatgaggatg gggctattta tttgatttat tccaattcaa atttgatggc acttttaggc
    27781 tgttcaaagt caaaattact ctccatgtga gtttgaagtg acatttttag atgattacca
    27841 taaaaaacat aactacccac tattttacga atcctatctt caaaacgtta tggaattcct
    27901 tgaaagtcaa gacataaaga atggggttga tgcctttgta gatgatcatc aaaatctcgt
    27961 ttttgtttta tatggacaag gctatcgagc cgagggaaaa gagggaatac ttacaaccca
    28021 agtaactgta aaagcttatg atgaagacaa gaaaccgatt aacttcgcaa atttattaga
    28081 ttccttaatt tattagattc cttaatcgtc tcagaatatc aaatggaacc gaatctttgg
    28141 gaggtctccc atgattgatc tctatctaag taaaaataga caaagaaatc aacttctttt
    28201 agatttcttc caaaactatg gcatagaggt atcttgtcat tcagtttctg aaatgacaaa
    28261 ggacaaatta attgagatga tgagctattc ttcagattgt tttgagtttt tatctcccaa
    28321 tttattacga tttaagaacc gtgacaatct aagattaacg gatttcgttg agataatttt
    28381 aaaaaatcct gaactaacca tcagacttcc tcttgcggtt tcaaataagc gagtttatcc
    28441 aagtctgaat ttggaagagg ctagagctct attgccaaga gatacgaaac aattgattta
    28501 catggcgcaa acacattatt tatctaacta aaggagaagc aatatggctg aacgattttg
    28561 ggagaacttg tccattattt tggctgaaag aaatatcagc tggattgagt taaccagaaa
    28621 aatgtttgcg ggagagtttc actatccaag tgaattgaat cgtttgtatc aaaagattcg
    28681 ccactagaag atggaacaat gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt
    28741 attagattta gattatgaag atttatttcg gaggtaacta tgaaaagaat aattccagtt
    28801 tatatattcc aacaagtaaa tgtcctattg gtatctctat acttattgaa atttctttgt
    28861 atcggtgagt taactatact acagattctc tatggttcgt cactcatttc ttttttatgg
    28921 atgtatggcc aacgcaaaca agcgcataag gtcaatatga aatctaggat gaaatggctt
    28981 ggtgttgaat ttgttagcct actgattata agtctatgtt ttagtctgat tcatgctcaa
    29041 ggaagcacga atcaagcaaa cttaattggc cttcaacatc aaattccttg gttttcattt
    29101 ttattgttct taatcaatgc gagtatggtt gaagaatttc tgtatcgaga aattttatgg
    29161 aatttggtca gaaaattaga tatcagagtt gctttgacaa gtgttttatt tgccttagca
    29221 catcatacag gaaccattct agcttggtgt ttgtatgttt cacttgggat gtttttaggt
    29281 atggtgcgct ataaatctga cttatggggc agtatgggac tacatttggt gtggaaccta
    29341 ctagtttata gtttgctgct tttttaaaat aggtgacctg atttttaggt aacttctaaa
    29401 actaacttcc agttttggga gagagatgga agttactttg aaaagttacg gaaacattat
    29461 tttctatgtg acaacattgt ataattgctt gcattttact ggtggagaga gtataatgag
    29521 ggtggataaa gtacttaatc ccaaaaattt aaataggagg agctagctat ggcagaagaa
    29581 gtattaaatc ttcaattagt atctgttcaa gttgacgaaa cagatgaagt tgatggaatg
    29641 cgatttagta cattcagtac aaa
//
LOCUS       DBERDS010000022        29068 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.022, whole genome shotgun sequence.
ACCESSION   DBERDS010000022 DBERDS010000000
VERSION     DBERDS010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29068
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.022"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            14..827
                     /locus_tag="ACL73E_001144"
                     /pseudo
     CDS             14..827
                     /locus_tag="ACL73E_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            849..1588
                     /locus_tag="ACL73E_001145"
                     /pseudo
     CDS             849..1588
                     /locus_tag="ACL73E_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            1601..2767
                     /locus_tag="ACL73E_001146"
     CDS             1601..2767
                     /locus_tag="ACL73E_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS0801121.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(3258..4928)
                     /locus_tag="ACL73E_001147"
     CDS             complement(3258..4928)
                     /locus_tag="ACL73E_001147"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGS0801122.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVDAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWGKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            5158..5847
                     /gene="coaB"
                     /locus_tag="ACL73E_001148"
     CDS             5158..5847
                     /gene="coaB"
                     /locus_tag="ACL73E_001148"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGS0801123.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            5859..6410
                     /gene="coaC"
                     /locus_tag="ACL73E_001149"
     CDS             5859..6410
                     /gene="coaC"
                     /locus_tag="ACL73E_001149"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGS0801124.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            6394..6957
                     /locus_tag="ACL73E_001150"
     CDS             6394..6957
                     /locus_tag="ACL73E_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0801125.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGITLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            7239..7766
                     /locus_tag="ACL73E_001151"
     CDS             7239..7766
                     /locus_tag="ACL73E_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0801126.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            7778..8293
                     /locus_tag="ACL73E_001152"
     CDS             7778..8293
                     /locus_tag="ACL73E_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGS0801127.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(8290..8757)
                     /locus_tag="ACL73E_001153"
     CDS             complement(8290..8757)
                     /locus_tag="ACL73E_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGS0801128.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(8830..9318)
                     /locus_tag="ACL73E_001154"
     CDS             complement(8830..9318)
                     /locus_tag="ACL73E_001154"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801129.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(9284..9847)
                     /locus_tag="ACL73E_001155"
     CDS             complement(9284..9847)
                     /locus_tag="ACL73E_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS0801130.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            complement(9857..11845)
                     /gene="uvrB"
                     /locus_tag="ACL73E_001156"
     CDS             complement(9857..11845)
                     /gene="uvrB"
                     /locus_tag="ACL73E_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGS0801131.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(11922..12875)
                     /locus_tag="ACL73E_001157"
     CDS             complement(11922..12875)
                     /locus_tag="ACL73E_001157"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGS0801132.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAIVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            13045..15210
                     /locus_tag="ACL73E_001158"
     CDS             13045..15210
                     /locus_tag="ACL73E_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGS0801133.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            15210..15950
                     /locus_tag="ACL73E_001159"
     CDS             15210..15950
                     /locus_tag="ACL73E_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0801134.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            16099..17586
                     /gene="zwf"
                     /locus_tag="ACL73E_001160"
     CDS             16099..17586
                     /gene="zwf"
                     /locus_tag="ACL73E_001160"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGS0801135.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(17632..18909)
                     /gene="ftsY"
                     /locus_tag="ACL73E_001161"
     CDS             complement(17632..18909)
                     /gene="ftsY"
                     /locus_tag="ACL73E_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGS0801136.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(18913..19731)
                     /locus_tag="ACL73E_001162"
     CDS             complement(18913..19731)
                     /locus_tag="ACL73E_001162"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0801137.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(19731..20525)
                     /locus_tag="ACL73E_001163"
     CDS             complement(19731..20525)
                     /locus_tag="ACL73E_001163"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0801138.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            complement(20522..24061)
                     /gene="smc"
                     /locus_tag="ACL73E_001164"
     CDS             complement(20522..24061)
                     /gene="smc"
                     /locus_tag="ACL73E_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGS0801139.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(24052..24750)
                     /gene="rnc"
                     /locus_tag="ACL73E_001165"
     CDS             complement(24052..24750)
                     /gene="rnc"
                     /locus_tag="ACL73E_001165"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGS0801140.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(24933..25004)
                     /locus_tag="ACL73E_001166"
     tRNA            complement(24933..25004)
                     /locus_tag="ACL73E_001166"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24969..24971),aa:Arg,seq:ccg)
     gene            complement(25068..26054)
                     /locus_tag="ACL73E_001167"
     CDS             complement(25068..26054)
                     /locus_tag="ACL73E_001167"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGS0801141.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(26229..27545)
                     /locus_tag="ACL73E_001168"
     CDS             complement(26229..27545)
                     /locus_tag="ACL73E_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGS0801142.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IVVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(27532..>29068)
                     /locus_tag="ACL73E_001169"
     CDS             complement(27532..>29068)
                     /locus_tag="ACL73E_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGS0801143.1"
                     /translation="IRFNFENPIFDMKRSTNEFIGRSAMVTKLLCIYTEGDPFFGVNI
                     NSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKLGTMLFEYSKLFMENKE
                     DNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTDGNEDQIGFVQ
                     FHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGGQDNFDEAWDS
                     YLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYELYKDKNYNKQ
                     EYYKSGGKTVLETLRKRFGLKDYISPEEVETDKKFVFIIDEINRGEISKIFGELFFSI
                     DPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFDFAMRRRFRFV
                     EVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPSYFLKLKDVDF
                     DYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVADDNEGDENDD
                     ADY"
BASE COUNT         8502 a         6388 c         5325 g         8853 t
ORIGIN      
        1 gagttttctg acaatgaatc aatcctactt ttatctaaaa atgaaagaac acaaactcaa
       61 ggttccttat acaggtaagg agcgccgtgt acgtattctt cttcctaaag attatgagaa
      121 agatacagac cgttcctatc ctgttgtata ctttcatgac gggcaaaatg tttttaatag
      181 caaagagtct ttcattggac attcatggaa gattatccca gctatcaaac gaaatccgga
      241 tatcagtcgc atgattgtcg ttgctattga caatgatggt atggggcgga tgaatgagta
      301 tgcggcttgg aagttccaag aatctcctat cccagggcag cagtttggtg gtaagggtgt
      361 ggagtatgct gagtttgtca tggaggtggt caagcctttt atcgatgaga cctatcgtac
      421 aaaagcagac tgccagcata cggctatgat tggttcctca ctaggaggca atattaccca
      481 gtttatcggt ttggaatacc aagaaaaaat tggttgcttg ggcgtttttt catctgcaaa
      541 ctggctccac caaccgctat atcgagtgcc agaaactatc gcctgaccaa cgcatcttca
      601 tctatgtagg aacagaagaa gcagatgata cagacaagac cttgatggat ggcaatatca
      661 aacaagccta tatcgactcg tcgctttgct attaccatga tttgatagca gggggagtac
      721 atctggataa tcttgtgcta aaagttcagt ctggtgccat ccatagtgaa atcccttggt
      781 cagaaaatct accagattgt ctgagatttt ttgcagaaaa atggtaagtt aagaaaggaa
      841 aaaacgaaat gcatattgaa catcttagcc actggagtgg tcatcctaac cgtgaaatgt
      901 accttaaccg ttatggacat ggtgggattc cagttgtggt ctttgcttca tcaggtggta
      961 gtcacaacga atactatgat tttggcatga ttgatgcctg tgcttccttt atcgaggaag
     1021 gccgtgtcca gttctttacc ctatctagtg tggatagtga gagctggttg gctacttgga
     1081 aaaatgctca tgaccaagcg gaaatgcacc gtgcctacga acgttatgtg attgaggagg
     1141 ccattctttt atcaagcaca agacaggtta gtttgatggc atgatgacga caggttgctc
     1201 tatgggagcc tatcatgcac tcaatttctt cctccagcat ccagatgtct ttaccaaagt
     1261 gattgctctc agtggtgttt acgacgcacg tttctttgtc ggtgattact acaacgatga
     1321 tgctatttac caaaactcgc cagtagatta tatttggaac caaaacgatg gctggtttat
     1381 tgaccgttac cgtcaggcag agattgtgct gtgtacgggg cttggagcct gggaacaaga
     1441 tggtttacca tccttttaca agctcaaaga agcctttgac cagaaacaaa ttccagcctg
     1501 gtttgctgaa tggggacatg atgtcgccca cgactgggaa tggtggcgta aacaaatgcc
     1561 ttatttcctc ggtaatctct atttataaaa ggagttacct atgaattacc ttgttatttc
     1621 tccctactat ccacaaaact ttcaacagtt taccatcgaa ctagctaata aaggcatcac
     1681 agtcttggga attggtcaag agtcttacga gcaattggat gagcccttgc gcaatagctt
     1741 gaccgagtat tttcgtgttg ataatcttga gaacatagat gaagtcaaac gtgcagttgc
     1801 ttttctcttt tataaacatg gtccaattga ccgcatcgag tctcacaatg aatactggct
     1861 tgagctagac gcaacactca gagaacaatt caatgttttt ggtgccaaac cagaggatct
     1921 caaaaagacg aaatataagt ctgaaatgaa gaaacttttc aaaaaagcag gtgttcctgt
     1981 ggtacctgga gctgttatca agacggaagc agatgttgat caagcagtga aagaaatcgg
     2041 tcttccaatg attgccaaac ctgataatgg agtgggagca gccgcaacct ttaaacttga
     2101 gacagaagac gatatcaatc acttcaagca agaatgggac cattcaaccc tttatttctt
     2161 tgaaaaattt gtcacttcca gcgaaatctg tacctttgac gggctcgtgg acaaggatgg
     2221 aaagattgtc ttctcaacaa cctttgacta cgcctataca ccgcttgacc tcatgattta
     2281 taagatggac aattcttatt atgtgctcaa ggatatggat cctaaactgc gcaagtatgg
     2341 ggaagcaatt gtcaaagaat ttggtatgaa agaacggttt ttccatattg agttcttccg
     2401 tgagggggac gattatatta ccatcgagta caataaccgc cctgcaggtg gttttaccat
     2461 tgatgtttat aactttgctc attccttgga cctttatcgt ggctatgcag ctattgtcgc
     2521 aggagaggag ttcccggcgt cagactttga aactcagtat tgtttggcta cttctcgccg
     2581 tgcaaatgct cactatgttt attcagaaga ggatttgctt gccaaatata gccagcagtt
     2641 caaggttaaa aaagtcatgc cagctgcctt cgcggaactt caaggagatt acctgtatat
     2701 gctgacaact ccgagtcgac aagaaatgga tcagatgatt gctgatttcg gacaacgtca
     2761 agaataagaa ctatcggatt aaggaaattc actcccttaa tccttttgtt ttgtctggta
     2821 aaaaataaga gcatcctaac aaggtagcta tcataaaact tgttcgataa ctatttgaag
     2881 caggattagg tggctagaaa ttgaatttta acatttcaat ttagtcatag tattgtgttt
     2941 tcgtatcctt aaatcagcta aaaggatcca tgacgacacc tatacgatat agttttcagg
     3001 ataccaaacc agtctattaa tactcaatga aaatcaaaga gcaaactagg aagctagccg
     3061 caggttgctc aaaacactgt tttgaggttg tggatagaac tgacagagtc agtatcatat
     3121 acctacggca aggtgaagct gacgtagttt gaagagattt tcgaagagta taaatcttat
     3181 tgatgaactg cttgcagtct gagaaaaaat gagcttggat attatttcca aactcactta
     3241 aagtcaattt caatccacta gaacaagcct agtacagttc catcgctttc aacatccatg
     3301 ttgagagctg ctggacgttt tggaagacct ggcatggtca taacatcacc agttaaggca
     3361 acgatgaagc ctgcacctaa ttttggtacc aattcacgaa tggtaatttc aaagttttct
     3421 ggtgctccaa gcgcatttgg attgtctgag aaactgtatt gagttttagc catacaaatt
     3481 ggcaatttgc cccaaccatt ttgaacgatt tgagcaattt gtgtttgagc tttcttctca
     3541 aagttcactt tgctaccacg atagatttca gtgacaattt tttcaatctt ttcttggaca
     3601 gaaaggtcat tatcgtacaa acgtttatag ttagctggat tttcagcaat tgtcttaaca
     3661 actgtttcgg caagtgctac tccaccttct gctccatcag cccagacact agccaattca
     3721 actggtacat cgattgaggc acagagttct tttaaggctg caatttcagc ttctgtatca
     3781 gatacaaatt cgttaatagc tacaactgct ggaataccga acttacggat attttcaacg
     3841 tggcgtttca agttagcaaa acctgcacga actgcatcta cattttcttc agtcagagcg
     3901 tctttagcca caccaccatt catcttaagg gcacgaaggg ttgcgacaat aacaactgca
     3961 tctggagatg ttggcaagtt tggtgtcttg atatcaagga atttctcagc accaaggtcc
     4021 gcaccaaaac cagcttcagt aacagtgtaa tcagccaagt gaagggctgt tgtcgtcgcc
     4081 aaaacagagt tacagccatg agcgatattg gcaaatggac caccgtgtac aaaggcaggt
     4141 gtaccgtaaa ttgtctgaac caagtttggc ttaatagcat ccttcaaaat caaagccaag
     4201 gcaccctcaa cctgcaaatc acctacagaa acaggcgtac ggtcatagcg ataaccaata
     4261 acgatattcg ccaaacgacg tttcaagtcc tcgatgtccg ttgccaagca aagaattgcc
     4321 atgatttctg aagcaactgt aatatcaaaa ccatcctcac gtggaatacc gtttagagga
     4381 ccaccaagac caacagtcac atggcggagc gcacggtcgt tcaagtccac aacgcgtttc
     4441 cagaggatac gacgttgatc aattcccagc tcattccctt ggtgcaagtg gttgtcaatc
     4501 aaggcagaaa gggcattgtt ggcagttgta atagcatgca tatctccagt aaagtggagg
     4561 ttgatgtctt ccattggcag aacttgtgca tacccaccac cagcagcacc acccttgatc
     4621 cccatgactg gaccaagaga cggttcgcgg atagcaatca tggttttctt gccaatcttg
     4681 ttcaaggcat ccgcaagacc aatggtaagc gtcgactttc cttcacctgc aggtgttggg
     4741 ttgatggcag taaccaagat caatttacca actggattgc tctcaactgc acgaatttta
     4801 tcaaagctga gtttagcctt gtactttccg tacaactcca aatcgtcgta agaaatacca
     4861 agtttctcta caacatcaac aattggcttc aactcaatac tctgtgcgat ttcaatatct
     4921 gttttcattc aaaattcctc taacctctta tatgataatt cattatatca caaaacaaga
     4981 tttttaacat cctaaaactc tctaaacgtt cgtaaatatc tctgttttta aggcttttag
     5041 agtcctttct taaattttat atggctttat agtttgaaac tatagtaaat cttcgttttt
     5101 accaaaaatt tatcactttc attttactta ccgcttattt ttgtgtacaa tagtgctatg
     5161 aaaattttag ttacatcggg cggtaccagt gaagctatcg atagcgtccg ctctatcact
     5221 aaccattcta caggtcactt ggggaaaatt atcacagaga ctttgctttc tgcagggcat
     5281 gaagtttgtt taattacgac aaaacgagct ctgaagccag agcctcatcc taacctaagt
     5341 attcgagaaa ttaccaatac caaggacctt ctaatagaaa tgcaagaacg tgttcaggat
     5401 tatcaggtct tgatccactc aatggctgtt tctgactaca ctcctgttta tatgacaggg
     5461 cttgaggaag ttcaggctag ctccaatcta aaagaatttt taagcaagca gaatcatcag
     5521 gccaagattt cttcaactga tgaggttcag gttttgttcc ttaaaaagac acccaaaatc
     5581 atatccctag tcaaggaatg gaatcctact attcatctga ttggtttcaa actgctggtt
     5641 gatgttaccg aagatcatct ggttgacatt gcacgaaaaa gtcttatcaa gaatcaagca
     5701 gatttaatca tcgcgaatga cctgactcaa atttcagcag gtcagcaccg agctatattt
     5761 gttgagaaaa atcagcttca aacagtccag actaaagaag aaattgcaga actcctcctt
     5821 gaaaaaattc aagcctatca ttcttagaaa ggaaaactat ggcaaacatt ctcttggctg
     5881 taacgggttc aatcgcctct tataagtcgg cagatttagt cagttctcta aaaaaacaag
     5941 gccatcaagt cactgtctta atgactcagg ctgctacaga gtttatccaa cctttgacac
     6001 tacaggtact ctcacagaat cctgtccact tggatgtcat gaaagaaccc tatcctgatc
     6061 aggtcaatca tatcgaactt ggaaaaaaag cagatttatt tatcgtggta cctgcaactg
     6121 ctaacactat tgcaaaacta gctcacggat ttgcggacaa catggtaacc agtacagctc
     6181 tagccctacc aagtcatatt cccaaactaa tagctcctgc tatgaataca aaaatgtatg
     6241 accatccagt aactcagaat aatctgaaaa cattagaaac ctacggctat cagctgattg
     6301 ctcctaagga atccctacta gcttgtggag accacggacg aggagcttta gctgacctca
     6361 caattatttt agaaagaata aaggaaacta tcgatgaaaa aacgctctaa tattgcaccc
     6421 attgctatct tttttgctac catgctcgtg atacactttc tgagctcact tatctttaac
     6481 ctttttccat ttccaatcaa accgaccatt gttcatattc ctgtcattat tgccagcatt
     6541 atttatggtc cacgagttgg gattacactt ggatttttga tgggattact tagcttgacg
     6601 gttaacacga ttacgattct accgacaagc tacctcttct ctcccttcgt accaaacgga
     6661 aacatctact cagctatcat tgccatcgtc ccacgtattt tgattggttt aactccttac
     6721 ttagtctata aactgatgaa aaacaagact ggtctgattt tagctggagc ccttggttcc
     6781 ttgacaaata ctatctttgt ccttggagga atcttcttcc tatttggaaa tgtttataat
     6841 ggaaatatcc aacttcttct ggcaaccgtt atctcaacaa attcaattgc tgaattggtc
     6901 atttctgcaa ttctaaccct agccattgtt ccacgactac aaaccttgaa aaaataaaaa
     6961 caatctccgc tttcaaacct gaaggtggag attttgctct atacagtttc tttttaatga
     7021 aatctttact atagtaaaac gaaataagaa caggacaaat cgatcaggac agtcaaatag
     7081 atttctaaca atgttttaga agtagaggtg gactattcta gtttcaatct actataactt
     7141 ttaactaaaa aatgatctat aaacccaagt aaattcttgc tttattgtct ggtttattgt
     7201 accatactag tgtatatgca gttaaaaagg agattcttgt gaatacacgg aaaaagacac
     7261 aatttatgac aatgacagcc cttttaacgg ctattgcgat tttgattcca attgttatgc
     7321 ctttcaagat tgtcattcca cctgcttcct atactttggg gagccacatc gctattttta
     7381 tagccatgtt cttgtcgccc ttgatggcag tttttgtcat cctagcctct agttttggat
     7441 ttttgatggc tggctatccc atggttatag tttttcgggc tttttcccat atatcttttg
     7501 gtgctttagg agctctttac ctacaaaaat tccccgatac cctagataaa ccaaaatctt
     7561 cctgggtttt caattttgtt ttggctgttg ttcatgccct tgctgaagta ttagcctgtg
     7621 tcctttttta cgcaacttcg ggtaccaatg tagaaaacat gttctatgtt ctatttgtac
     7681 tagttggatt tggcacaatt atccatagta tggtagacta tacattagca ctagctgtct
     7741 ataaagtgct tcgaaaacgc cgttaaaagg aaaagctatg acaaaagatc gcaaacaagc
     7801 cctgctccaa ctcttgaaag aagctcctaa agcccttaat ggccaaagtt tggcggaaca
     7861 ttttcatgtc acacgtcagg tcattgtgca ggacattgca attttgagag ccgatggcgc
     7921 tcctatccta tccaccaatc gtggctacat ctataagcaa attgatacca atccttatgt
     7981 tcacaaactt ttcaaagtga aacatgaagt tgaagaaatc ggtcaggaac tccttgctat
     8041 tgtcgataat ggtgggcatg tccagaatac tttgattgac catcccgttt atggagaaat
     8101 tgaaaccttg cttaaactgt cttgccgccg agacgttcaa cattttctag aacaagtcga
     8161 gcattctgat tttaaacctt tatctgaatt gacagatggt gtccattacc acctagtcga
     8221 agccgaaaca caacaagacc tccactatat cgaggaggcc ttggatcagc taggttattt
     8281 agtaaaggat tagaaaattt tcttttccca atcgtcttct gtacggcgag ggtagaaaaa
     8341 ttcagatttg tccgatgctt ccatcatctc catcaaaggt agcatatcat aggccagatc
     8401 caagtttgga atctggtctt tttgcaccca agaaacttct ccttcatctg aagagcgaag
     8461 ggtaccagag aactcagttg ccttataaca aacgacaata tagcgcccac ctgtatctag
     8521 tggccaattt ttaatgccga caagttgagg attttggata gtcaaccctg tttcttcata
     8581 gatttcacga atgacagact ctgcgaaaga ttcgccattt tctacatggc ctcctggaaa
     8641 ggcataacca gaccagcgat tagtttcagg agcgcgatac tgcatcacca cgcgctgagc
     8701 ttcgagatct tcaatcagac aaatatttgt taaaatcgtt aattgtgctc gagacataaa
     8761 tttactcact ttctaattta ttaaattttt agacttgata ccagtaccat tagcttctac
     8821 tttttaaaat tatttagaat agaataccat ccgtttttcc tttatgggct ttccaagttc
     8881 aagtatcttt tcttgttcat caaaagtaaa gcccattttt tgatagaaag caattgcgcg
     8941 cttattatct ttcaataccc ataagaaaat ttcagaaaaa tgattaagag caatcaaagc
     9001 tgcttttatt aacttttgtg cgataccttt tccataatag tcttttaaaa catataaagc
     9061 aataatttcg ccagcttgaa tagtctcatc acgaaagttg ccataactga taaaaccaac
     9121 taccttcata ccatccatcg caatcaatgt attttctgga tacttttgac taaagaatcg
     9181 acatctttct aatgtcattg tctcctgaaa ttctgcaggc aaaaggccat cataagcctc
     9241 tctccacgtt tgccagtgaa caaggggctt accttctatc tcttcaggag tttccattga
     9301 tttgataata accgtcattt gttttctccc agtcttctct caaaatacca tatttaatac
     9361 tatcaaaata tttaccttga taataacgaa cttttggaat atgagcttct tttttcattc
     9421 ttaatttttc agcaagtttc atcataccaa gattccctga ccaagttgtc aaacccagat
     9481 gctccaactc caagtaatcc tgaaacgtcc tatctatcca ctgcaacata gcaactttcc
     9541 caataccagt gttccagaat tttttatcat aaataccaat tcccaattcc atccatcttg
     9601 tttgtttaca tacccaataa cgcgaaacag tcccaactag tttatcatca acaaaaatac
     9661 caaggcgatt tgagttgctt aaaatggatt ctgatttttg tagttcgaat tctttaaaat
     9721 ttgaaaaata ctgataatca tcataatagg gagcatcata ctgtttccaa actggattaa
     9781 gttgtgaata agccatttcc cataaagaca tcaaatcttc tctctttaac tttcttaaat
     9841 aaatcatact attcccctaa tccaaggcct tgacttccaa catcatatca cggatctgag
     9901 ccgccagttc aaagtcaagt acttcgacgg cttcttgcat ttgtttttct agtttcttga
     9961 cgagttcttt gcgctcttgt ttgttgaggc tattgatgtc gacttccttg tcctcttcct
    10021 tagcaactgc cttggtcaca gcaatcaggt cacggatttc tttcttgatt gtctgtggta
    10081 cgataccatg ctcttcatta taggccatct gaattttccg acggcgggca gtttcatcga
    10141 tagcacgttg catagactgg gtaaccgtgt ctgcatacat gatgacatgg ccttcactgt
    10201 tacgagcagc acgtccaata gtctggatga gtccacgttc gttgcgaagg aaaccttcct
    10261 tgtcagcatc gagaatagct acgaggctca cttcaggaac gtcaattcct tcacggagca
    10321 ggttaattcc gaccaagaca tcaaagacac ccaagcgcag gtcacggata atctccgtcc
    10381 gttccaaggt cttgatatcc gagtgcatgt acttaacctt gatacccatt tccttgaagt
    10441 agtcggtcaa gtcctctgcc attttcttgg tcaaagttgt gataaaggta cgctcatttt
    10501 tttcaacgcg ggcattgatt tcacccaaga ggtcatcaat ctgtcccata gtcggacgga
    10561 cttccacctc tggatccaag agtcccgttg gacgaatgat ttgctcaatc actgtctcgg
    10621 tctgttcatt ttcatagtca ccaggtgtcg ctgaaacgta aacaatctga tgaacgtgac
    10681 tctcaaactc ctcccgacgg agaggacgat tgtccaaagc agacggcaaa cggaaaccat
    10741 aattaaccag catttcttta cgcgaacggt ctccattgta catgcccttg atttgcccta
    10801 tggtcatatg actctcgtca atcataatca agaaatcatc tgggaagaag tcgagaagcg
    10861 tataaggagg ctctccttcg ctccgtccat ccatgtggcg agaataattt tcaaccccat
    10921 tggtatagcc catctcacgc aacatttcga tatcatactc tgtccgctgt ttcaaacgct
    10981 gggcttcaag cagtttacct tccttttcaa agacagctaa ttgttcttcc aactcggcct
    11041 gaatctttgc aatggcaact tccatgtggt cgtcattggt cacaaagtgt gtcgctggga
    11101 aaatcgctaa atgatccact tctcccaaca cctgacctgt cagagcctca acttcacgaa
    11161 tacggtcaat ttcgtctcca aaaaattcta ctcgaaaggc atgttcatct cgggaagctg
    11221 ggaaaatctc taccacatcc ccacgaacgc gaaatcttcc gcgttggaaa tcaatatcat
    11281 tgcgttcaaa ctgaatatcg accaagtcat tcaagagttt atcacgagaa atctctagac
    11341 caggacggag actaacgaca ctatcagcgt attccttggg cgaacccaaa ccatagatac
    11401 aagagactga ggccacgaca ataacatcat tacgctccaa aagggctgag gtagctgagt
    11461 ggcgaagctt gtcaatctcg tcattgacag aactatcctt ctcaatatag gtatcgctag
    11521 aagggacata ggcctctggc tggtaataat catagtagga tacgaaatac tcaactgcat
    11581 tttcagggaa aaattcctta aactccccat agagctgacc agccagagtt ttattgtggg
    11641 caataaccag agttggttta ttgactttag aaatgacctg actcatagta taggtcttcc
    11701 ctgttccagt cgcccccatc agaatctgag ctttttctcc cccctcaatg ttatccacca
    11761 actgctcgat agcttggggt tgatctcctg atggttgata ttttgatact agtttaaatt
    11821 gattatctgt aatgtgattg atcataagaa tcctctctcc atgtgctatt cctattttag
    11881 catacttata gtattttcac gaagaaaagg acggaccgaa gtcacatcct ttcattttct
    11941 ttctttaatt tattagcaag atagacaatc agcagtagta ataccagact tgtcataatg
    12001 gaaccttcta tgccaaaaga accacctgat aaccaatctt gattgccttg tggtaaaaag
    12061 gtcatcagag acgttcctga cggttgacca ctaactaaaa tcccaaagag attaccctga
    12121 gcaaaattcc aagcaccatg aatacctgca acaccccaaa ctgtatcagt tttgagaagg
    12181 taaagagcca tggcaactcc gaataaaaag agatttacta gagatagagg ggtgaggcca
    12241 gaattgccca tatgaagcag ggtaaagaac aggctagata taagaatagc tagttttaga
    12301 ttggttcttg aggccaattg aggaagtagc caagcacggg ccaccacttc ttctgctgtc
    12361 ccctgtaaaa tccaaaatgg gatagtaaag acgacaaagg caagagaata aggattcaag
    12421 tgaatggatt ccaaacgata ttgacctaag accaccaaac ctaacaaggt cagaagaaaa
    12481 agtgccagac ctagactaaa tcctttcaga agattgctga ggcaattctc tctataaaat
    12541 cccaaggttc gaataggtct tttctcaact tttcttgtcc atctgaacac agtgttaaga
    12601 ataaaaccaa aggccagtaa tcctaaaatt aaacgaaagt cacttgtttt atccgtcaag
    12661 ctctgatgca aggtctgcaa gtaggttgca agattttgac cagcctctcc aaaatttcta
    12721 gcaagtccga tgagagctaa caagccaata ccatacaaag taaaagccac aaactctcct
    12781 atgaagacaa aaacaatggc taacaagggg cttgtgtaaa tgtttaaact catttttgaa
    12841 gcttggaagt ctttaaatat tcttttgttc ttcatatccc cgtcctcttt tcttctatat
    12901 atactattat tatagcactt tttaatagca attcaagaaa aggaaaaaat caatgttata
    12961 ttttctgaca cgaaaaatat aaaaatttgc ctttttttac tttttctgat ataatgagag
    13021 aatattcgga aaaggagact aaaaatgaag aaaaaatttc tagcattttt gctaatttta
    13081 ttcccaattt tctcattagg tattgccaaa gcagaaacga ttaagattgt ttctgatacc
    13141 gcctatgcac cttttgagtt taaagattca gatcaaactt ataaaggaat tgatgttgac
    13201 attattaaca aagtcgctga gattaaaggc tggaacattc agatgtccta tcctggattt
    13261 gacgcagcag tcaatgcggt tcaagctggg caagccgacg ctatcatggc agggatgaca
    13321 aagactaaag aacgtgaaaa agtcttcacc atgtctgata cttactatga tacaaaagtt
    13381 gtcattgcta ctacaaagtc acacaaaatt agcaagtacg accaattaac tggcaaaacc
    13441 gttggtgtta aaaacggaac tgccgctcaa cgtttccttg aaacaatcaa agataaatac
    13501 ggctttacta ttaaaacatt tgacactggt gatttaatga acaacagctt gagtgctggt
    13561 gccatcgatg ccatgatgga tgacaaacct gttatcgaat atgccattaa ccaaggtcaa
    13621 gacctccata ttgaaatgga tggtgaagct gtaggaagtt ttgctttcgg tgtgaaaaaa
    13681 ggaagtaaat acgagcacct ggttactgaa tttaaccaag ccttggctga aatgaaaaaa
    13741 gatggtagtc ttgataaaat tatcaagaaa tggactgctt catcatcttc agcagtgcca
    13801 actacaacta ctctcgcagg attaaaagct attcctgtta aggctaaata tatcattgcc
    13861 agcgattctt cttttgcacc ttttgttttc caaaattcaa gcaatcaata cactggtatt
    13921 gatatggaat tgattaaggc aatcgctaaa gaccaaggtt ttgaaattga aatcaccaac
    13981 cctggttttg atgctgctat cagtgctgtc caagctggtc aagccgatgg tatcatcgct
    14041 ggtatgtctg tcacagatgc tcgtaaggca acttttgact tctcagaatc atactacact
    14101 gctaatacca ttcttggtgt caaagaatca agtaatattg cttcttatga agatctaaaa
    14161 ggaaagacag tcggtgttaa aaacggaact gcttctcaaa ccttcctaac agaaaatcaa
    14221 agcaaatacg gctacaaaat caaaaccttt gctgatggtt cttcaatgta tgacagttta
    14281 aacactggtg ccattgatgc cgttatggat gatgaacctg ttctcaaata ttctatcagc
    14341 caaggtcaaa aattgaaaac tccaatctct ggaactccaa tcggtgaaac agcctttgcc
    14401 gttaaaaaag gagcaaatcc agaactgatt gaaatgttca acaacggact tgcaaacctt
    14461 aaagcaaacg gtgaattcca aaagattctt gacaaatacc tagctagcga atcttcaact
    14521 gcttcaacaa gtactgttga cgaaacaacg ctctggggct tgcttcaaaa caactacaaa
    14581 caactcctta gcggtcttgg tatcactctt gctctagctc ttatctcatt tgctattgcc
    14641 attgtcatcg gaattatctt cggtatgttt agcgttagcc catacaaatc tcttcgcgtc
    14701 atctctgaga ttttcgttga cgttattcgt ggtattccat tgatgattct tgcagccttc
    14761 atcttctggg gaattccaaa cttcatcgag tctatcacag gccaacaaag cccaattaac
    14821 gactttgtag ctggaaccat tgccctctca ctcaatgcgg ctgcttatat cgctgaaatc
    14881 gttcgtggtg gtattcaggc cgttccagtt ggccaaatgg aagccagccg aagcttgggt
    14941 atctcttatg gaaaaaccat gcgtaagatt atcttgccac aagcaactaa attgatgttg
    15001 ccaaactttg tcaaccaatt cgttatcgct cttaaagata caactatcgt atctgctatc
    15061 ggtttggttg aactcttcca aactggtaag attatcattg ctcgtaacta ccaaagtttc
    15121 aagatgtatg caatccttgc tatcttctat cttgtaatta tcacactttt gactagacta
    15181 gcgaaacgct tagaaaagag gattcgttaa tggcaaaatt aaaaattgat gtaaatgatt
    15241 tacacaagca ctatggaaaa aatgaagtcc taaaaggaat tacgactaag ttctatgaag
    15301 gagatgttgt ttgtatcatc ggtccttcag gttctggtaa gtcaactttc ctccgtagcc
    15361 tcaatctttt agaagaagtc actagcggtc acatcactgt gaacggctat gatttaactg
    15421 aaaaaacaac caatgttgac cacgtccgtg aaaatatcgg catggtattc caacacttca
    15481 acctcttccc tcatatgtct gtattggaca acatcacctt tgctcctatt gagcacaagt
    15541 tgatgactaa ggaagaagct gagaaattgg gaatggagtt gcttgaaaag gttggactag
    15601 cagataaagc taatgccaat ccagatagcc tatcaggtgg tcaaaaacaa cgtgtggcca
    15661 tagctcgtgg cctagcaatg aatccagaca tcatgctctt cgatgaacca acttctgccc
    15721 ttgaccctga gatggttgga gacgtactta acgttatgaa ggaattggct gagcaaggca
    15781 tgaccatgat tatcgtaacc catgagatgg gatttgctcg tcaggttgcc aaccgcgtta
    15841 tctttactgc agatggcgag ttccttgaag acggaacacc tgaccaaatc tttgataacc
    15901 cacaacaccc tcgtctgaaa gagttcttag ataaggtctt aaacgtctaa actcaaactg
    15961 taaggatttc cttgcagttt ttctacctcg tattggaatt tttgattttt cggaaaatta
    16021 tgttagaatt aagtttatga aatgaggttt cctcatacct agcaagacta ggaataaaaa
    16081 tagaaattag gtagctagat gtcatctaag gttattgtta caattttcgg tgcgagtgga
    16141 gacctggcta aacgcaagct ctacccttcc ctttttagac tatataaatc cggcaatctt
    16201 tccaagcact ttgccgttat tggaactgcc cgtagacctt ggagtaagga atattttgaa
    16261 tctgtagttg tcgagtccat ccttgatttg gcagatagta ccgagcaagc ccaagaattt
    16321 gctagccact tctactatca aagccatgat gtcaatgatt cggaacatta tattgctttg
    16381 cgtcaattac aagctgagct taatgaaaaa taccaagctg aacacaataa gctcttcttc
    16441 ttgtctatgg cacctcagtt ctttggaacc attgccaaac acctcaaatc tgaaaacatt
    16501 gtcgatggca aaggttttga gcgcttgatc gttgaaaaac catttggtac agattacgca
    16561 actgcaaaca agttgaatga cgaactccta gcaacatttg acgaagaaca aattttccgt
    16621 atcgaccatt atcttggtaa ggaaatgatc caaagcatct ttgcagttcg ctttgcaaac
    16681 ttgatttttg aaaacgtttg gaacaaggat tttatcgaca atgttcaaat tacctttgcg
    16741 gagcgcttgg gtgtagaaga acgtggtggc tactatgacc aatccggtgc cctccgtgac
    16801 atggtccaaa accacactct acaacttctt tcgctcctcg ccatggacaa accagcaagc
    16861 ttcacaaaag acgagattcg tgctgaaaag attaaggtct ttaaaaacct ctatcatcca
    16921 actgatgaag aactcaaaga acactttatc cgtgggcaat accgctctgg taagattgat
    16981 ggcatgaaat acatctctta tcgtagcgag ccaaatgtga atccagaatc aacaactgaa
    17041 acctttacat ctggtgcctt ctttgtagac agcgatcgat tccgtggtgt tcctttcttt
    17101 ttccgtacag gtaaacgact gactgaaaaa ggaactcatg tcaacatcgt ctttaaacaa
    17161 atggattcta tctttggaga accacttgct ccaaatattt tgaccatcta tattcaacca
    17221 acagaaggct tctctcttag cctaaatggg aagcaagtag gagaagaatt taacttggct
    17281 cctaactcac ttgattaccg tacagatgcg actgcaactg gtgcttctcc agaaccatac
    17341 gaaaaattga tttatgatgt cctaaataac aactcaacta actttagcca ctgggatgaa
    17401 gtttgtgcgt catggaagtt gattgaccgt attgaaaagc tctgggctga aaatggtgcc
    17461 ccacttcatg actataaagc tggaagcatg ggacctcaag ccagctttga cctacttgaa
    17521 aaattcggtg ccaaatggac ttggcaacca gatatcacct atcgtcaaga tggtcgctta
    17581 gaataaaaaa atttcctgca agtttatgcc ttgcaggatt tttgcttctg attagattaa
    17641 accttccaag agacctttca taaagttttc tgagttaaac tctccaatat catcgatttt
    17701 ttcaccaaaa ccaatcaatt ttacaggaat attgagttct tcacgaatgg ctagaaccac
    17761 acctcctcga gcagttccat caatcttagt caaaacaatt cccgttaaag gtgtgatttt
    17821 cgaaaattct ttggcctgta ctagggcatt ttgacctgtt gatgcatcaa gtgccaagaa
    17881 ggtttcatgt ggtgcttctg gcacaacacg tttgataata cgaccaatct tttccaactc
    17941 agccataagg ttatccttat tttgcagacg accagcagta tcaatcatga gaatatcgat
    18001 accttcagcc acggcacgtt ccataccatc aaagaccacg ctggctggat cagctttttc
    18061 aggtccagtt actactggaa catctactcg tcggccccat tcagctagct gagctactgc
    18121 acccgcacgg aaggtatctg ctgcaaccag catgaccttc ttaccagctt gtttgtagcg
    18181 gtgggctagt tttccgatag aagttgtttt cccaacacca ttcacaccaa caaagagcat
    18241 aactgtcaag ttatcttgga agtggatgct ttcatcgtag ctaccatcct tttcataaag
    18301 ctcaaccaat ttctcaatga tgacacgacg aagtgcatca ggtttcttgg cattttcaag
    18361 cttggcttcg taacgtagtt cctccgttaa gttagaagcg acttggacac caacatcact
    18421 cataatcagc agttcttcca gttcctcgaa aaattcttcg tcaacagagc ggaagttagc
    18481 aaagaaggca ttcaagcggg caccgaaacc tgtacgagtt ttcttaagac tgcggtcata
    18541 tttttcctga acggtttctt ctgcttgagg cctttctggt tcaagaactt cagaattatt
    18601 ttcttctata gtctctagaa actcagtatt cccttcttct gagtgtggaa attcttcgac
    18661 ttctttttga gaaacttcta caactggctc taaatccaga ctttcttcaa ctgtgtcttg
    18721 gatttcctct tcttggaaca cagcttgttc aacaatttca acctctgctt cttcctgaga
    18781 aacttcctca acttctgtga aggtaggatc aacatcttca gacaaatcaa gattttccag
    18841 agcttctttt acaacttctt cgattttagg ttcttctttt tttccgaata gacggtcaaa
    18901 caatcccata tcttagttct cctttagcac atattcttcg atagcccagg cgacagcttc
    18961 ctcatcgttg gtcatcggcg tcactacatt tgcggctgcc tttacttcag gaacagcgtt
    19021 ttgcatagca acaccaagac ctgcccattc aatcatagag aggtcattgg cctcgtcacc
    19081 acaagccatc acttgacttt ggtcgattcc aagatggctg attagttttg ccaaacctgt
    19141 tgctttatga acattctttg gtgaccattc tagcaacatt tcacgtgatt taaagatttc
    19201 atattggtca aacaattctg gagaaatctt ctgaatggct gcatccaagg gttcttgagc
    19261 aaaggcagtc acgcatttgt tgtaggtcat ttgactagat aagtcttcaa agtccactgg
    19321 aacaaaggtc aaagctggat tgaatttggc ataaagactt tcttggtccg attggatttg
    19381 ataaactgtt ccttctgaga tggcatcaag aggcagtgat aatttctctg tttcttcata
    19441 caaacgtgcc acatcatcat atgaaaagac tgttttatca aggatttctc ctgtattttt
    19501 ctgaactaat ccaccattaa aagtaatggt atactcatct tcctgaccgt cagtccctaa
    19561 ctcatggaga aagaaatcca tggcttttaa gggacgacca gttgtcaata cgaccttgat
    19621 accacgatca cgcgcagctt tcaaggtttc cttggtacga tccgtcagcc ttttatcagt
    19681 agtcagcaag gtcccgtcca agtccaatgc aatcaatttt atatctgcca ttataagccc
    19741 tccatataag ctataaccga ccgttcctta tggtgaccaa tcacagtctt tgctaattct
    19801 aaaatttcag gtcgtgcatt ttcaggagct acaggatgtc ccacaacctg catcatatgt
    19861 aagtcattaa gattgtctcc aaaagccatg acctgatcca ttgtgatacc aagtttttta
    19921 gctaattcaa caatagctac acccttatcg acatagtcca gaacaatatc aatagattca
    19981 aagccagttg tcatggcctt aacaccaggg acatgttcat taacccaagc ttcaccagct
    20041 tctagcgttt cttctgtgaa gttggttgta aatttgaaaa tgtcatctgt gatatcttcc
    20101 aaactcgcta ctttttggat attttcatta taatgctgac tcactttcaa ataggtctca
    20161 tcaaccgtat ctagaacata tgaacccttc ttacccgtca agagcagttt attgatatct
    20221 acataaggtg acgttttcag cttttcaaaa gttgccagat aaaagtcacg agacatagtc
    20281 gcttcataca agtcctgacc ttgatactct accaaactgc cattttccgc gatgaaaata
    20341 atgtcatcac gaacatcagc aaataatttt tccagagaca gaaatccccg acccgaagcc
    20401 accgcaaagt aaatcccttt ttccttgtag gaagccaaga gagacttgag acgatccata
    20461 tcaaagcgtc cattcccatc taggaaggtt ccgtccatat ccgttgctac tagtttaatt
    20521 gtcatccttc aatactttct aaatctttta acttaactga aacaatcttt gaaacacccg
    20581 attcttgcat ggtcactcca tagatggaat cagccgctgc catggttccc ttacggtggg
    20641 ttacaacgat aaactggctg tccttgtcaa agcggttgag gtaatcccca aaacgtttaa
    20701 cattggcttc atccagcgca gcttccacct catccaagat gacaaaagga atggtcttga
    20761 cacgaataat ggagaaaagc aaggcaagag ccgatagagc tttttcacca ccactcatga
    20821 ggttaagcga ctggattttc ttacctggag gttgaacaga aatctccaca ccagctgtta
    20881 aaaggtcgcc ctcagtcaat atcaagtctg cctgacctcc gccaaacatc tgcttgaagg
    20941 tcactttaaa ggactcacga atagcttcaa aggttgattt aaagcgttcc ttgacctcat
    21001 cattcatctc tgtaatggtt tcaaggagca gatttttcgc tgacaaaata tcatctcgct
    21061 gactatttag aaagtccaga cggttgtgaa cttcttcgta ctggtcaata gcttccaagt
    21121 tgacaggtcc caatgagcga atagccttct ctaaatcctg cacctcttgc tctgccagat
    21181 tgaggttttc caattcatgt gccttttcta gtgcttcagt atagctaatc tggtactggt
    21241 ctgttaattg attttgtaga tggcgcaagc gctcgctgac cttttctttc ttggcttcag
    21301 cacgtgtttg cttgcgaatc cactcctcat tctgctggcg agcttgatcc aagtgactgg
    21361 caatatcatc cagttgacct tctatatcat ccaactcaaa ctgcttgcga atcaaacctt
    21421 gttggagatt tgttttctga gttttggatt cttccgcctg ttgactgagc aattctgtat
    21481 caaccttctc aagattgtca actttttctt ggagcatgcg ctgaatttct tcttgttcga
    21541 tattaagatt gtccaattcc ttgcctaaac gctcaatatc agctacttca taacgttttt
    21601 gcccttgcag ttctgtctta agcaagcgag cttgcgccac ctcttcctgc aaattttgat
    21661 agcgttcttg gatggcgttt ttattagact taatttcttc aatctcagct tccagatttt
    21721 gcttttcact ggcgatagta gcaaggctct cttgacattt ttccttatcc gcttgccaat
    21781 ctccctcaga aagacgatct atttcctctt cttggagttt ccaaagagtt tccagttctt
    21841 caacttgctg actagtttgc tgataagcga gggacaagcc ttgctcctga atacgtgcct
    21901 gctctccttg agatttgatg gcttctaatc tttctgtcaa tgcagccatc tggtcttgca
    21961 aggtcttcaa agccgcttct tctgaaccca agcttgcttc atctgcagca atttcttttt
    22021 gtaattgctc cagttctggc ttgatgaaaa tactgttatt ttggcgattg gcaccacccg
    22081 cataggaacc acccgtgcgt aattctgtcc catccaatgt caccatacga acctgataac
    22141 gaacttgtcg agcagcttca cgcgcatgtt ctacggtatc aaagatagcc gtcgtagcta
    22201 gcaagttctt gaaaatggct tccagtctag tatcaaaagt caccaactca tctgccatcc
    22261 caaggaaacc tgggcttaca gcgatagcat cttggttctg actagaaatc gtacgcgcct
    22321 taatagtggt caaaggaaga aaggttgcac gaccgactct gtttcgtttg aggaaatcaa
    22381 tagctttggt tgccgactct tcatcttcta cgatgatatg ctggctactt gcccctaagg
    22441 caatctctag ggcagtttga taataaacat caaaggtcag atgctcactg actgcaccaa
    22501 taatcccacc taggcgatct ttttcttgga gaacactctt aacacctgca taaaagttac
    22561 tatgatttct caggatattt tccaaacttt gagctctggc ctgcttgttt ttgagactat
    22621 ccagacggtc aaagagttga ctttgttgag cttgatagga agttttctgc tcctcttgct
    22681 ccttggcaat agcttgatag tcagccaata atttctgaac ctgcaccttg gcagtttcaa
    22741 gctcgtcttt ttgctgacta gccttctctt tagctgtagc taattgctct ttcagctttt
    22801 ctagttgatc tgcttgtttt tgagaaagct gacgactatt ttccaactca ttctcaatac
    22861 gggtcaactg gtttgagaca tccgcttctt cttgtaaaag agctacaaag cgttcacgta
    22921 agagctcaat catctgatca ggatcgtctg agaaagccag caattcagct tctaaacgat
    22981 tgagtttttg attattttgg actagatttc cctctaacag agctaaagag ctttctttat
    23041 catacttttc tttgctgagt gaatttctct tatcctccaa agcagccaaa cgagcttgtg
    23101 cctcctgttg attcagggcc acttgctcgg actccagttt cgatagggct aattttcttt
    23161 ctaaatcact aatcagacta gtcaagtcca tcaaactgcc ttggtctttg gccatttcag
    23221 cctgtaaatc ttggcgttgc tttttaagag tttgattttc ttcttctaat ttttcacgct
    23281 tttggtaata actcatcaag agttcttgaa cctgagccaa ctcttcttct gtcgactcta
    23341 gttctgcctt attttccttg atttgagcaa ccagaacgtc taaataaata gccttacgtt
    23401 gtccttccaa gtctaaaaac ttacgggcat tctcagcttg cttctcaaga ggcttgattt
    23461 gattatccaa ctcgtagata atgtcctcta agcggtccag attatcctga gtttgctgca
    23521 gtttactctc ggtttctttt ctgcgagtct tgtattttaa aactccagca gcttcttcaa
    23581 aaatagctcg tcgttcctca ggcttggaat taaaaatctc ctcaaccttc ccttgggaaa
    23641 taatagagaa ggaatctcgt cccaatccag tatccaagaa gaggtcatga atatcacgca
    23701 gacggacttt cttgccgtca atcttgtatt cgctatctcc actacgatag atatggcgtt
    23761 ccaccctgat ttcttgacct gcatccttga taaatccgtc atgattatcc agagtcacaa
    23821 ctacagaagc ataattgagc ggtttgcgac tttctgttcc agcaaagatg acatccggca
    23881 tcttgccccc acggagactc ttgacactag actcccccaa agcccaacgc agactttctg
    23941 taatattgga ctttccagat ccattgggtc caacaactgc cgtcacacct tggtcaaaaa
    24001 cgaccttggt cttatcagca aaagacttga acccctgaat ttcgatttcc tttaaataca
    24061 tgaatccagc cctttctcaa cggcattttt ggcagcttcc tgctctgcta atttcttaga
    24121 acgaccttgg ccttgaccga tgctcttacc ttcaacaaga acttctacat caaagacctt
    24181 atcgtgagca ggccctgttt cagaaatcac ttgataacga atagccacat caccattgac
    24241 ctgaagcaac tcttggagat gggttttata gtctgtaatc atctcaaatt cgcctgcttc
    24301 taccttagga atcataactt ggtagataaa ttccttgacc tttgccacat ccttatccaa
    24361 aagaagggca ccaagaaagg cttcaaaggc atcaccaaga atggtgtcac gattgcgacc
    24421 accagatttt tcttcccctt tacccaactt gataaactgg tcaaactggc aatcacgcgc
    24481 aaaaccagct aaactctcct cacggacaat catagcacgg agttttgata ggtcaccttc
    24541 aggcttttta ggatattttt tatatagata ttctgaaatc aataactgta gaacagcgtc
    24601 tcctaaaaat tccaagcgtt cattgtgtga aatttttaag aggcggtgct cattggcata
    24661 actcgtatga gtaaaggcag tttccagtaa ctttttgtct gcaaattcga tttcaaaatg
    24721 attctttagt acagtttgta attctttcat accaacttct ttctaactga taatagtcct
    24781 ttttattata tcaaaaaaag ccccctgagt cactctaaaa cgggactgga aagcatttgg
    24841 gaattcttta gacagagatt ctcagtttta gcggcaaatt tgggtcagga taaagaaaaa
    24901 agccctatta aaggcttttt aggatgttta catccaccct gagggaatcg aacccccatc
    24961 tcaagaaccg gaatcttacg tgatatccat tacactaagg gtggaaactt gttttattat
    25021 aacagaaatt tgctctaata acaagttttt tggtcaaaga ccccgtctta gtgggaagca
    25081 tccccattcc agatggagtt tttcacgatc acataatcaa cgtgtttaag gtcagcaacc
    25141 tgacgtccac ctgcataaga aatagcactt tgaaggtctt gttccatctc agttaaagtg
    25201 tcttgcagat gacctttagc aggaagcaag atacgtttgc cttccacatt tttgtaagca
    25261 cctttctgat attgtgaggc tgaaccataa tattctttga actgttcacc atcgacttca
    25321 atcgttttcc ctggactttc aatgtgtcct gcaaagaggg aaccaatcat gatcatgcta
    25381 gcaccgaagc ggatagactt ggcaatatca ccgtgagtac gaattcctcc atcagcgata
    25441 atcggtttac gcgcagcctt ggcacaccag cgtagagcag ccaactgcca accacctgta
    25501 ccaaaaccag tcttaacctt ggtgatacaa accttaccag gaccgattcc gaccttagta
    25561 gcatctgcac cagcattttc caattcacgc acagcttctg gtgttcccac atttccagca
    25621 atgacaaagg tatctggcaa ttctttcttg atgtgttgaa tcatagaaat cacgctatcc
    25681 gcatgaccat gagcaatatc aatagtgata tactcaggag catcagcctt gagctggcta
    25741 acaaaatcat actcataatc cttaacaccg acagatatgg aagcaatgag cccttgatcg
    25801 tgcattcgtt taataaaagg aatgcgtcct gcctcatcaa aacggtgcat aatgtagaag
    25861 taaccacctt tagccagttg ctctgctaca ttttcatcca aaatcgtctg catattcgct
    25921 ggcacaacag gtagtttaaa ggtgtgattt cctaaagtga cacttgtatc cgcttctgca
    25981 cggcttttaa tgacacattt atttggaatc aattgaatat cttcgtaatc aaaaattgga
    26041 aattcattta acatatcgat gtctcgtttc ttttgtaatg acctacctat gctctcgcat
    26101 cactacgcct tttccgacgt ttccttaatt tattataaac caaagtacag tttttgtcaa
    26161 attattttat gaattaaaat atattgttcg gattttgctt gtgttaaaaa taaaagaaag
    26221 aggggaaatt attttctccc cacttcttca tcaataatcg ctttaaaatt ttcttctgaa
    26281 ttttccatca ttttacaaaa tgcactataa gatgaagact tctgaggaat ttggatagac
    26341 catttcttca acaaagctcc ataacctgct aggtttccta tctcattatc aatgaccttg
    26401 tccttgctcg gaaaaacaag tccagccttc tcagctttta aaatataaga ataggaaatc
    26461 agctggaata agtcctcacg gttgattcct ttttcagtca attccagttt tttatatttt
    26521 gcatctagaa caatctttcg ttctctgtca taaaaatctg gatatacttt tcgtttccca
    26581 acagaaaata ctgaaattcc atccgtctta tccttatttc tgggatgtac aaaacctttt
    26641 ggcaacaagg tgtaaacata ctcttcccaa agccaggcaa catcaaagag aataccatag
    26701 attttttgat cttgataccc taaaccgtgc ttttcttggt ttaggatcat cagacaaagt
    26761 tcttgtaagt ttctgtactc gtgaaagtat gcatgacgta taggtttaga ttgatttctc
    26821 cgagtaatct tagcacgatc agctagttta taagagggcg ttacacgcac gatttcagat
    26881 acgttttcac gactagttga gagattatct agtacccctt gaccaatgct tttctgattc
    26941 ttaatgtatt caatagtgtg acggaccaac tgcatgaggg gattatcata ggtgaactct
    27001 ctcgttgtgt aggcaatatt tcccgtgaaa ggaagatttt tcttgagatg gtttcttaca
    27061 acaatcactc ccttaacatt actgtcgtta tgagaaaatc gatgatattc cttataaaga
    27121 ccttttcgaa tagcagcttg tagatacttg gggaagagat acatcaaaag ttgataaagc
    27181 ctctcttcac gagacaaagc aacatctaaa ctagtgagat tgatataaag aaccttgttt
    27241 aagagataat gcaaaaaatg gtcattactc tcatcagaaa atcgtgagga aatcgttaat
    27301 ctttcctgac catatccaag aaaaccaatc acgttccctg tcttgatttt ctgattgact
    27361 gtttcaaaaa tcttttgatc cttatccaaa tcaggagtat gagtcaaatc atttggaaaa
    27421 atgaaaatac gttcatcttg ggatagactt tccaaggttc tgtctaaaag aagattgctt
    27481 agtttaggat attcttcaac aaatttttct ttaataatct tgtgttgatt atcagtaatc
    27541 cgcatcatcg ttttcatcac cttcattgtc atcagctact gcctgatctt tttgctcatt
    27601 atttgtcagt tcaaatgctt ttttcaaagt ttccaaagtt tcaacctcat cataagaacc
    27661 tcgcaagtag tcttctagga gaggcttaat ataatcagac cagagtaatt catagtcaaa
    27721 atctacatcc ttcaacttaa gaaaataact tggtccaata tgataatgac tgtttaattc
    27781 ctgaacattt tcgatagcag cgttcaagtt tcttagacga atttttgctt cttctgcatg
    27841 gatattcagc tctttatcca acatgccaac ttgaccctcg gcagtaactt caacaaaacg
    27901 aaaacgacga cgcatagcaa aatcaaaggt atccactgaa cgatcaatat cattcatagt
    27961 tccgatgatg taaacatttt cggggatata gaacttttca tcagtttcgt gtagatttgc
    28021 atattgggta gaaacacttc ctttttcacc acgatagcca gggtcgatag aaaaaaagag
    28081 ttcgccaaaa atcttagaaa tctccccacg attgatctca tcgatgatga aaacaaattt
    28141 cttgtctgtt tcaacctctt ctggagaaat atagtctttc aaaccaaatc tctttctcaa
    28201 tgtttctagg acagtttttc caccactttt gtagtattct tgcttattat aatttttatc
    28261 tttatacaac tcgtaaacat atttgctagg tagtgaccat cctggaacac cactatcata
    28321 atttactgac aaattttgtc tactattaac agataagtaa gatgtttttg ttatatattc
    28381 tttttcttca gcaacattta tatattctaa gtaagaatcc caagcctcat caaaattatc
    28441 ttgtcctcca atcaattggg tttcttttgc tttctgacaa aaatctttaa aaataccgtc
    28501 ctgtagccta aactcaatag ctccatcccc atttgatact ggtcttaaac cttctacaaa
    28561 atccgtataa tcataggatg ggtgaaattg tacaaatccg atttggtctt cgttaccatc
    28621 cgttaattct ttggcaattt ctttagcaag ataagtcttt cctgtgccag gagcaccacg
    28681 aaggataagg tttggagact ttaatagaga ttgagttaat tgatgactaa aattgtttga
    28741 tgaatccatt gtactattgt cttccttatt ttccataaaa agcttagaat actcaaaaag
    28801 catagttcct aatttcgatg gctccaactc aggataagtt ttggacacca gttcaattat
    28861 tttatgattt tgcagataag gtccaccttg atttgtctga gaaacaaagt ggttccaaaa
    28921 ttctttctga ctattaatat ttacaccaaa gaaaggatct ccctcagtat agatacaaag
    28981 taattttgtc accatagcag aacgaccaat aaattcattt gttgatcttt tcatatcaaa
    29041 aataggattt tcaaagttaa aacgaata
//
LOCUS       DBERDS010000023        26567 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.023, whole genome shotgun sequence.
ACCESSION   DBERDS010000023 DBERDS010000000
VERSION     DBERDS010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26567
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.023"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..990
                     /gene="lytB"
                     /locus_tag="ACL73E_001170"
     CDS             <1..990
                     /gene="lytB"
                     /locus_tag="ACL73E_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGS0801144.1"
                     /translation="LKSDGKIAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKTTNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1051..2706)
                     /gene="pavA"
                     /locus_tag="ACL73E_001171"
     CDS             complement(1051..2706)
                     /gene="pavA"
                     /locus_tag="ACL73E_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGS0801145.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKITSMKKS"
     gene            2811..3308
                     /gene="ybeY"
                     /locus_tag="ACL73E_001172"
     CDS             2811..3308
                     /gene="ybeY"
                     /locus_tag="ACL73E_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGS0801146.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3289..3684
                     /locus_tag="ACL73E_001173"
     CDS             3289..3684
                     /locus_tag="ACL73E_001173"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS0801147.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3701..4600
                     /gene="era"
                     /locus_tag="ACL73E_001174"
     CDS             3701..4600
                     /gene="era"
                     /locus_tag="ACL73E_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGS0801148.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4649..5473
                     /gene="mutM"
                     /locus_tag="ACL73E_001175"
     CDS             4649..5473
                     /gene="mutM"
                     /locus_tag="ACL73E_001175"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGS0801149.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5473..6078
                     /gene="coaE"
                     /locus_tag="ACL73E_001176"
     CDS             5473..6078
                     /gene="coaE"
                     /locus_tag="ACL73E_001176"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGS0801150.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6065..7264
                     /locus_tag="ACL73E_001177"
     CDS             6065..7264
                     /locus_tag="ACL73E_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGS0801151.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRIFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7264..7413
                     /gene="rpmG"
                     /locus_tag="ACL73E_001178"
     CDS             7264..7413
                     /gene="rpmG"
                     /locus_tag="ACL73E_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0801152.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7453..7686
                     /gene="secG"
                     /locus_tag="ACL73E_001179"
     CDS             7453..7686
                     /gene="secG"
                     /locus_tag="ACL73E_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGS0801153.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7788..10142
                     /gene="rnr"
                     /locus_tag="ACL73E_001180"
     CDS             7788..10142
                     /gene="rnr"
                     /locus_tag="ACL73E_001180"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGS0801154.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQTLGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDTVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10105..10572
                     /gene="smpB"
                     /locus_tag="ACL73E_001181"
     CDS             10105..10572
                     /gene="smpB"
                     /locus_tag="ACL73E_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGS0801155.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10588..11448
                     /gene="tehB"
                     /locus_tag="ACL73E_001182"
     CDS             10588..11448
                     /gene="tehB"
                     /locus_tag="ACL73E_001182"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGS0801156.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11521..12474
                     /gene="coiA"
                     /locus_tag="ACL73E_001183"
     CDS             11521..12474
                     /gene="coiA"
                     /locus_tag="ACL73E_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGS0801157.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12493..14295
                     /gene="pepF"
                     /locus_tag="ACL73E_001184"
     CDS             12493..14295
                     /gene="pepF"
                     /locus_tag="ACL73E_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGS0801158.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14297..15010
                     /locus_tag="ACL73E_001185"
     CDS             14297..15010
                     /locus_tag="ACL73E_001185"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGS0801159.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            15077..16018
                     /gene="prsA"
                     /locus_tag="ACL73E_001186"
     CDS             15077..16018
                     /gene="prsA"
                     /locus_tag="ACL73E_001186"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGS0801160.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16137..16478)
                     /locus_tag="ACL73E_001187"
                     /pseudo
     CDS             complement(16137..16478)
                     /locus_tag="ACL73E_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16892..16987
                     /locus_tag="ACL73E_001188"
                     /pseudo
     CDS             16892..16987
                     /locus_tag="ACL73E_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(17240..17860)
                     /locus_tag="ACL73E_001189"
     CDS             complement(17240..17860)
                     /locus_tag="ACL73E_001189"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGS0801161.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(17860..18342)
                     /locus_tag="ACL73E_001190"
     CDS             complement(17860..18342)
                     /locus_tag="ACL73E_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGS0801162.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18342..19184)
                     /locus_tag="ACL73E_001191"
     CDS             complement(18342..19184)
                     /locus_tag="ACL73E_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGS0801163.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSH
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19279..20079)
                     /locus_tag="ACL73E_001192"
     CDS             complement(19279..20079)
                     /locus_tag="ACL73E_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGS0801164.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20223..21602
                     /gene="glmU"
                     /locus_tag="ACL73E_001193"
     CDS             20223..21602
                     /gene="glmU"
                     /locus_tag="ACL73E_001193"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGS0801165.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGNNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21612..22157
                     /locus_tag="ACL73E_001194"
     CDS             21612..22157
                     /locus_tag="ACL73E_001194"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0801166.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            22169..22483
                     /gene="macP"
                     /locus_tag="ACL73E_001195"
     CDS             22169..22483
                     /gene="macP"
                     /locus_tag="ACL73E_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGS0801167.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            22500..23192
                     /locus_tag="ACL73E_001196"
     CDS             22500..23192
                     /locus_tag="ACL73E_001196"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGS0801168.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            23269..23760
                     /gene="rocS"
                     /locus_tag="ACL73E_001197"
     CDS             23269..23760
                     /gene="rocS"
                     /locus_tag="ACL73E_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGS0801169.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23858..24448
                     /locus_tag="ACL73E_001198"
     CDS             23858..24448
                     /locus_tag="ACL73E_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGS0801170.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            24457..26220
                     /locus_tag="ACL73E_001199"
     CDS             24457..26220
                     /locus_tag="ACL73E_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGS0801171.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMDRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            26434..>26567
                     /locus_tag="ACL73E_001200"
     CDS             26434..>26567
                     /locus_tag="ACL73E_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS0801172.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     T"
BASE COUNT         8090 a         4824 c         5818 g         7835 t
ORIGIN      
        1 ctcaaatctg atgggaaaat agctgaaaaa gaatgggtct acgattctca tagtcaagcc
       61 tggtactact tcaaatctgg tggctacatg gcgaaaaatg agacagtaga tggttatcag
      121 cttggaagcg atggtaaatg gcttggagga aaaactacaa atgaaaatgc tgcttactat
      181 caagtagtgc ctgttacagc caatgtttat gattcagatg gtgaaaagct ttcctatata
      241 tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa gcgcttggct
      301 attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc gctagatgct
      361 agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca ctatgtggct
      421 cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg caagaaatat
      481 tattcggcag atggcctgca ttttgatggt tttaagcttg agaatccctt ccttttcaaa
      541 gatttaacag aggctacaaa ctacagtgct gaagaattgg ataaggtatt tagtttgcta
      601 aacattaaca atagcctttt ggagaacaag ggcgctactt ttaaggaagc cgaagaacat
      661 taccatatca atgctcttta tctccttgcc catagtgccc tagaaagtaa ctggggaaga
      721 agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga tacgacccct
      781 tacctttctg ctaagacatt tgatgatgtg gataagggaa ttttaggtgc aaccaagtgg
      841 attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc ttctggtatg
      901 aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt gatgatgaaa
      961 atcaatgaga agctaggtgg caaagattag tactataagt gaatatgatt tgagtgaata
     1021 gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg taattttttt
     1081 ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc cgggttttcc
     1141 accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca gattcgacag
     1201 gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtcttgactg catcagatgg
     1261 gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat ggaaccaaag
     1321 ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt ttcgtccgac
     1381 atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc gtttctggat
     1441 tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac ggatttcagc
     1501 gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat agagaatagt
     1561 ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga gtttctgata
     1621 ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa gcgcaatcat
     1681 gataggttgg ttggtatagt agttgtctag gataacctgg tcttggtcgt taggcacttg
     1741 gtggaggaag gttgtcagca attctccttt ttgacgaaat tcttcagcgt tgtctgtcgc
     1801 cagtaattct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt cattttcaac
     1861 acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct tatccttata
     1921 gtaggtgtcc aacaaatcag aaagatttgc aaaaggctct cccacctgat ttgcaaaagg
     1981 aactggactg aaggaagtct cagtcaagca tggcttggtt tcctgattga aaaaatttcg
     2041 gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgccg tatcgcgtcc
     2101 cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt gcaggatttc
     2161 aaagagcttt tcatccttga tagtaaaagg attgagagat tctgtacttg gcggagcgat
     2221 ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaagccga cgtgtttgat
     2281 aacttcgagg attttatgac tgcttttatc gaccagtaga atattactgt gtttccccat
     2341 aatttcgata atcaaggtag cctggatatg gtctccaatc tcgtttttat tggaaactgt
     2401 catttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg ccccctgcaa
     2461 atactttctc aaaaccatga taaaggtaga aggttgggct ggattttcaa aagtcgtttg
     2521 ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat ggctttggcg
     2581 attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt tctggatgcg
     2641 accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa atccgtcaaa
     2701 tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag gtagaataaa
     2761 atcatggaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac atgtatattg
     2821 aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc caagaaattt
     2881 tggaatttgc agccaaaaaa ttaggaaaag aagacaagga gatggcagtc acttttgtga
     2941 ccaatgagcg tagtcatgaa cttaatctgg agtaccgtga caccgaccgt ccgacagatg
     3001 tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag gatttgcttg
     3061 aaaatccaga attggcagag atgatgtctg agtttgatgc ctatattggg gaattgttca
     3121 tctctatcga taaggctcat gagcaggccg aagaatatgg tcacagcttt gagcgtgaga
     3181 tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac tatactccgg
     3241 aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat ggactcacaa
     3301 gacaataaac gaaaatggaa aaatcgtgac ctgatatcca gtttagaatt tgccatcaca
     3361 gggattttta ctgctatcaa ggaagaacgc aatatgcgaa aacatgcagt gacggctcta
     3421 gtggtcatcc ttgcaggttt tggttttcag gtgtcacgaa tcgaatggct ctttctccta
     3481 ttgagcattt tcttggtggt agcctttgaa attatcaatt ctgctattga aaatgtggtg
     3541 gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga tatggcggct
     3601 ggcgcggtat tagtggtttc tctttttgca gccttaacag gcgcattgat ttttctccca
     3661 cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta aatcaggctt
     3721 tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc acgttatggg
     3781 gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa tcatgggaat
     3841 ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc acaaacctaa
     3901 aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg aagtggacac
     3961 tgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata tgattatcga
     4021 gcgtctcaag gctgccaagg ttcctgtgat tttggtggtg aataaaatcg ataaggtcca
     4081 tccagaccag ctcttgtctc agattgatga cttccgtaat caaatggact ttaaggaaat
     4141 tgttccaatc tcagcccttc agggaaataa cgtgtctcgt ctagtggata ttttgagtga
     4201 aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagacc atccagaacg
     4261 tttcttggtt tcagaaatgg ttcgcgagaa agtcttgcac ttaactcgtg aagagattcc
     4321 gcattctgta gcagtagttg ttgactctat gaaacgagac gaagagacag acaaggttca
     4381 catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca tcggtaaagg
     4441 tggcgctatg cttaagaaaa tcggtagcat ggcccgtcgt gatatcgaac tcatgctagg
     4501 agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg ataaaaagct
     4561 agatttggct gactttggct ataatgaaag agaatactaa gtagaggtag gctcatgcct
     4621 gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg aaaccgtttg
     4681 tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa ttcgctaccc
     4741 caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc agattatcga
     4801 gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg tcttgatttc
     4861 ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg aacgcaagca
     4921 tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg atgttcgcaa
     4981 gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta tttctaaaaa
     5041 attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaat ctgcccttgc
     5101 caagtccaaa aagcctatca aatcccatct cctagaccag accttggtag ctggacttgg
     5161 gaatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta gaccttccca
     5221 gactttgaca gcagaagaag cgactgccat tcatgaccag accattgctg ttttgggcca
     5281 ggctgttgaa aaaggtggct ccaccattcg gacttatacc aatgcctttg gggaagatgg
     5341 aagcatgcag gactttcatc aggtctatga taagactggt caagaatgtg tacgctgtgg
     5401 taccatcatt gagaaaattc aactaggtgg acgtggaacc cacttttgtc caaactgtca
     5461 aaggagggac tgatgggaaa aatcatcgga atcactgggg gaattgcctc aggtaagtca
     5521 actgtgacaa attttctaag acagcaaggc tttcaagcag tggatgccga cgcagtcgtc
     5581 caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca ctttgggcaa
     5641 gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct catcttttca
     5701 aatcctgaag agcaaaaatg gtctaatcaa attcaagggg agattatccg tgaggaactg
     5761 gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga tattccccta
     5821 ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta tgtggaccga
     5881 gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga agctgagtct
     5941 cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca ggttcttgat
     6001 aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga gggaggtagg
     6061 caagatgaca gagattaact ggaaggataa tctgcgtatt gcctggtttg gtaattttct
     6121 gacaggagcc agtatttctt tggttgtacc ttttatgccc atcttcgtgg aaaatctagg
     6181 tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct ctgctatttc
     6241 cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc gaaaacccat
     6301 gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct ttgtcccaaa
     6361 tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt ttgttcctaa
     6421 tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg ccttaggtac
     6481 tttgtctaca ggcgtagttg caggtactct aaccggtccc tttattggtg gctttatcgc
     6541 agaattattt ggcattcgta cagttttctt actggttggt agttttctat ttttagctgc
     6601 tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg aaaaggctat
     6661 tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca atctcttttt
     6721 aaccagtttt gtcatccaat tttcagctca atcgatcggc cctattttgg ctctttatgt
     6781 acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg tgtccagtat
     6841 gggcttttcc agtatgatga gtgcaggagt catgggcaag ctaggtgaca aggtgggcaa
     6901 tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc tctgtgccaa
     6961 tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggcttgg gaaccggtgc
     7021 cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg gcatttcgag
     7081 gatctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc ccatggcagg
     7141 ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacaa gcctttgtgt
     7201 tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag taaaggaaat
     7261 ctagtgcgag taaaaattaa tctcaaatgc tcctcttgtg acagtatcaa ttacctaacc
     7321 agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg tcccaaggaa
     7381 agaaaagtaa ccctacatct tgaatctaag tagattttat ggtaaaataa tagggatttt
     7441 aaggagtttg atatgtataa cctattatta accattttat tagtattatc tgttgtgatt
     7501 gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt tgatgccagt
     7561 tcaggtgatt tgtttgaacg cagtaaagct cgcggttttg aagctgtaat gcagcgtttg
     7621 acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt attatcaagt
     7681 agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta aaggatgttt
     7741 gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg aaagatagaa
     7801 taaaagaata tttacaagac aagggaaagg tgactgttaa tgatttggct cagactttgg
     7861 gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta atggaaagaa
     7921 agcaccagat tcgctttgaa gaagatggta gtctgacatt agaaattaag aaaaaacatg
     7981 agattaccct caaggggatt tttcatgccc ataaaaatgg ctttggcttt gttagtctgg
     8041 aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct attgatggtg
     8101 ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca gcagcagaag
     8161 ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa atcgttctgg
     8221 atcaggaaaa gcctaagtat gctggctata ttcgttcaaa aaatcagaaa atcagtcaac
     8281 cgatttatgt taagaaacca gccctaaagt tagaaggaac agaagttctc aaggtcttta
     8341 tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc gatgtagtgg
     8401 gacactcaac ggatgtcgga attgatgttc ttgaggtctt ggaatcaatg gacattgtat
     8461 ccgagtttcc agaagctgtt gttaaggaag cagaaagtgt gcctgatgct ccgtctcaaa
     8521 aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt gacggtgcgg
     8581 atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc aatctggagc
     8641 ttggggttca catcgcagat gtttcttatt atgtgaccga ggggtctgcc cttgacaagg
     8701 aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca atgcttccag
     8761 aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg acccagtctg
     8821 ctattatgga gattgataaa catggtcgtg tggtcaacta taccattaca caaacagtta
     8881 tcaagactag ttttcgtatg acctatagcg atgtcaatga tatcctagct ggcgatgaag
     8941 aaaagagaaa agaatatcat aaaattgtat caagtatcga actcatggcc aagcttcatg
     9001 aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc aatgaagcga
     9061 agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag cgtggtattg
     9121 ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc gaacatttca
     9181 gcaagttgga tttgcctttt atctatcgaa ttcacgagga gcctaaggct gaaaaggttc
     9241 agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatgggact gccagtgaga
     9301 ttagtcagga ggcacttcaa gacatcatgc gtgctgttga gggagaacct tatgcagatg
     9361 tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag cacaatcacg
     9421 gccactatgg actagctgct gactattata ctcactttac cagtccaatt cgtcgttatc
     9481 cagaccttct tgttcaccgt atgattcggg attacggccg ttctaaggaa atagcagagc
     9541 attttgaaca agtgattcca gagattgcga cccagtcttc caaccgtgaa cgtcgtgcca
     9601 tagaagctga gcgtgaagtt gaagccatga aaaaggctga gtatatggaa gaatacgtgg
     9661 gtgaagagta tgatacagtt gtatcaagta ttgtcaaatt cggtctcttt gtcgaattgc
     9721 caaacacagt tgaaggcttg attcacatca ctaatctacc tgaattttat catttcaatg
     9781 agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg ggtcagcaga
     9841 tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt tcattcgtac
     9901 ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcgtagt ggcagagggc
     9961 gtggttcaaa tcgtcgttcg gataagaagg aagacaagag aaaattagga cgctcaaatg
    10021 ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg aaagaaacct ttttacaagg
    10081 aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt cgcacaaaat
    10141 aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat ggtcctgact
    10201 ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg ctttgctcaa
    10261 gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg cgccttacga agagggcaat
    10321 atctggaacc aggaaccaga acgtcgtcgt aaactcctgc tccataaaaa gcaaattcaa
    10381 aaattggaac aagagaccaa agggacagga atgaccttag ttccccttaa ggtctatata
    10441 aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga ctatgacaaa
    10501 cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat gaaagctgtt
    10561 aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa acgcatgcct
    10621 ttgtggaata aacaaacaat gcctgaagct gttcagcaaa agcacaatac aaaagttggg
    10681 acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt gacagaagaa
    10741 ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat ggcccaacct
    10801 caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt ggaattttat
    10861 tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca ttcagaggtc
    10921 ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttaggttg tggtcagggg
    10981 cgtaattctc tttttctagc ccagcaagat tttgatgtga cagctgtaga tcaaaatgga
    11041 ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat gcctgttggc
    11101 ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt ttcaacagtt
    11161 gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat gcaggagaaa
    11221 accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga ttatccttgc
    11281 tcggttaact tcccattcac ctttaaagaa ggagaactgg cagactatta caaggattgg
    11341 gaattggtta agtacaatga aaatccaggc catttgcatc gtcgcgatga gaatggcaat
    11401 cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac acacatgaag
    11461 attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag gagggaattc
    11521 atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga taaacttgag
    11581 aagcaagcat acacctgccc agcttgtgga ggccagctcc atttgcgtca aggaccaagt
    11641 gtacggacgc attttgccca taaatcctta aaagactgtg attttttctt tgaaaatgaa
    11701 agtccagaac acctggccaa taaggaatcc ctctatcact ggttgaaaaa agagacaaag
    11761 gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt tgtaaatggc
    11821 aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa agagcgaagt
    11881 gagggctatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa actgtggctc
    11941 aaggagcgtt tgactcgtct acagcaaggt tttctttatt tcagtcaaaa catgggcttt
    12001 tatgtttggg aattagacaa ggaaaaacaa gttttaagac tcaaatacct gatttaccag
    12061 gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggtca aggtagttta
    12121 ttggaaatat tgcgtcttcc ctataagaga caaaaaatat ctcattttac agtttctgag
    12181 gacaaggaca tctgtcgcta tatccggcaa caactttatt atcaaaatct cttttggatg
    12241 aaagaacaag cagaagccta tcaaaaggga gaaaatatcc tgacttatgg actgaaagaa
    12301 tggtatccac aaattcgacc aatagtgggc aaatttttcc agattgaaca agacttgact
    12361 agctattatc agcactttta tacctattac caaaaaaatc ctcaaaatga ttggcaaaag
    12421 ctttatccac cagcctttta tcagcaatat ttcttgaaaa atatggtaga atagaaagga
    12481 tggaggaatc taatggtatt acaaagaaat gaaataaatg aaaaagatac atgggatcta
    12541 tcaacgatct acccaactga ccaggcttgg gaagaagcct taaaagattt aacagaacaa
    12601 ttggagacag tagcccagta tgaaggccat ctcttggata gtgcggataa cctactagaa
    12661 atcactgaat tttctcttga aatggaacgc cagatggaga agctttacgt ttatgctcat
    12721 atgaagaatg accaggatac acgtgaagct aagtatcaag agtactatgc caaggccatg
    12781 acactctaca gccagttaga ccaagccttt tcattctatg agcctgaatt tatggagatt
    12841 agcgaaaagc agtatgctga ctttttagaa gctcaaccaa agctgcaggt ttatcaacac
    12901 tattttgaca agctcttgca aggcaaggat cacgttcttt cacaacgtga agaagaatta
    12961 ttggctggag ctggagaaat ctttggttca gcaagtgaaa ccttcgctat cttggacaat
    13021 gcggatattg tgttccctta tgtcctagac gatgatggta aagaagttca gctatctcat
    13081 gggacttaca cacgtttgat ggagtctaaa aaacgtgagg ttcgccgtgg tgcctatcaa
    13141 gctctttatg cgacttacga acaattccaa cacacctatg ccaaaacttt gcaaaccaat
    13201 gttaaggtgc aaaattaccg tgctaaagtt cgtaactaca agagtgctcg tcatgcagcc
    13261 ctcgcagcga attttgttcc agaaagtgtt tatgacaatt tggtagcagc agttcgcaag
    13321 catttgccac tcttacatcg ctatcttgag cttcgttcaa aaatcttggg gatttcagat
    13381 ctcaagatgt acgatgtcta cacaccgctt tcatctgttg aatacagttt tacctaccaa
    13441 gaagccttga aaaaagcaga agatgctttg gtagtcttgg gtgaggatta cttgagccgt
    13501 gttaaacgtg ccttcagcga gcgttggatt gatgtttacg aaaatcaagg caagcgttca
    13561 ggtgcctact ctggtggttc ttacgatacc aatgccttta tgcttctcaa ctggcaggac
    13621 aatctggaca atctctttac tcttgttcat gaaacaggtc acagtatgca ttcaagctat
    13681 actcgtgaaa ctcagcctta tgtttacgga gattactcta tctttttggc tgagattgcc
    13741 tcaactacca atgaaaatat cttgacggag aaattattgg aagaagtgga agacgacgca
    13801 acacgctttg ctattctcaa taacttccta gatggtttcc gtggaacagt tttccgccaa
    13861 actcaatttg ctgagtttga acacgccatt caccaagcag atcaaaatgg ggaggtcttg
    13921 acaagcgatt tcctaaataa actctacgca gacttgaacc aagagtatta tggtttgagt
    13981 aaggaagaca atcctgaaat ccaatacgag tgggctcgca ttccacactt ctactataac
    14041 tactatgtat atcaatattc aactggcttt gcggccgcct cagccttggc tgaaaaaatt
    14101 gtccatggta gtcaagaaga ccgtgaccgc tatatcgact acctcaaggc aggtaagtcg
    14161 gactatccac ttaatgtcat gagaaaagct ggtgttgata tggagaagga agactacctc
    14221 aacgatgcct ttgcagtctt tgaacgccgt ttaaatgagt ttgaagccct tgttgaaaaa
    14281 ttaggattgg cataaaatgg ttgaatcgta tagtaagaat gctaaccata acatgcgtcg
    14341 tcctgtcgtc aaagaagaaa ttgtagactt gatgcgtcag cgtcaaaagc aggtcacagg
    14401 tttcttgaaa gaattggaag actttgcccg caaggaaaat attcctatta ttccccatga
    14461 aacggttgct tatttccgtt ttcttatgga aaccatgcag cctaaaaata ttctggaaat
    14521 tgggacggct atcggttttt cagctctctt gatggctgaa catgcgccaa atgctaagat
    14581 tacaactatt gatcgtaatc cagaaatgat tggttttgcc aaggaaaatt ttgcccagtt
    14641 tgacagtcgc aagcaaatca ctctcctaga gggagatgcg gtggatgtct tatctacact
    14701 gacagagtct tatgatttcg tctttatgga ttctgccaag tctaaataca tcgtctttct
    14761 gccagaaatc ctcaaacatt tggaagttgg tggtgtggtt gtcttggatg atatttttca
    14821 aggcggtgat gttgccaagg acattatgga agtccgtcga ggtcagcgaa ccatctatcg
    14881 aggccttcaa agactatttg acgcaacctt agacaattca gaactcaccg caacattagt
    14941 gcctttagga gatggtattc tcatgcttcg taaaaatgta gcagatgttc aattgcctga
    15001 cagcgaatga ttttcagaaa aatttaagaa aaaatagtaa aatagataga gtaacactta
    15061 tctcaaagga gtagacatga agaaaaaatt attggcaggt gccatcacac tattatcagt
    15121 agcaacttta gcagcttgtt cgaaagggtc agaaggagca gaccttatca gcatgaaagg
    15181 ggatgtcatc acagaacatc aattttatga gcaagtgaaa aacaaccctt cagcccaaca
    15241 agtcttgtta aatatgacca tccaaaaagt ttttgaaaaa caatatggct cagagcttga
    15301 tgataaagag gttgatgata ctattgccga agaaaaaaaa caatatggcg aaaactacca
    15361 acgtgtcttg tcacaagcag gtatgactct tgaaacacgt aaagctcaaa ttcgtacaag
    15421 taaattagtt gagttggcag ttaagaaggt agcagaagct gaattgacag atgaagccta
    15481 taagaaagcc tttgatgagt acactccaga tgtaacggct caaatcatcc gtcttaataa
    15541 tgaagataag gccaaagaag ttctcgaaaa agccaaggca gaaggtgctg attttgctca
    15601 attagccaaa gataattcaa ctgatgaaaa aacaaaagaa aatggtggag aaattacctt
    15661 tgattctgct tcaacagaag tacctgagca agtcaaaaaa gccgctttcg ctttagatgt
    15721 ggatggtgtt tctgatgtga ttacagcaac tggcacacaa gcctacagta gccaatatta
    15781 cattgtaaaa ctcactaaga aaacagaaaa atcatctaat attgatgact acaaagaaaa
    15841 attaaaaact gttatcttga ctcaaaaaca aaatgattca acatttgttc aaagcattat
    15901 cggaaaagaa ttgcaagcag ccaatatcaa ggttaaggac caagccttcc aaaatatctt
    15961 tacccaatat atcggtggtg gagattcaag ctcaagcagt agtacatcaa acgaatagtc
    16021 caaatcaatg agtcagggaa aaaactcgac ttcaggaaaa aatgaagcaa acattcccac
    16081 aataaaacgc atagtacaag gtttgtactg ccccccaaaa aagttagaca attaatttat
    16141 ccgaaggatt tagttctgta ttgcacagag ctaagtcctt ttagttttat cttaattctc
    16201 ttattgttgt aataatcaat atagtctata atggcttgtt ccaattgatt aagtgattta
    16261 aatgtttgct catagccata aaacatttcg gattttaaaa tgccaaagaa agattccatc
    16321 ctaccgttgt cttggctgtt tcctttgcgt gacatagatg cttgaattcc cttactctct
    16381 aggaagcgat gataagaatc gtgttggtat tgccagcctt ggtcactatg gagaatcgta
    16441 ttctcgtagt gcttctcttt gaatgcctgt tccaacatta acgatcaatc aatttaatca
    16501 tgtacctaat attagaattg tttatctcaa atttatttga aagtttctct aagctatatc
    16561 cttgttttct aagttcatag atctgaactt tatcatcata agttaatttc ataataaaaa
    16621 caccccaaaa gttagatttt ttctgtctaa cttttggggg gcagttcatt taacacctga
    16681 taatatgcgt tttttgattt taaagacttt ttgaccagtc tcattttttt aacttgatac
    16741 tcagtgcaaa gcaaagatta aactaggaag ctagctgtag gctgctcaaa gaacagcttt
    16801 gaggttgtag ataaaacttg tgaggtcacc aacatatata atgtgaagct gacgtggttt
    16861 gaatagattt tagaagagta tgagtctgga agttttaatg gataatgcaa gattccatag
    16921 aatgggtaag ctagagttct tatgtgaaga gtttgggcat aaacttttac cttttcctcc
    16981 ctactcatct tagtatagaa aagtgaatct gaaatagtac ataactgctt ctaaaacatt
    17041 cttataaatt gatttaaatt ctcaaatcat attattcagt tcttatttca ttttgttcta
    17101 caatcctgtt gagaagacac gtgttcatat caaaaaggta ttggcaagtt gcaatacctt
    17161 tttacgaggc tctgttgtct tatttttgtt tcaactgact atatctccta tggttctagt
    17221 tcagaaggct aggctataat tatgattgat aagaagtatc attccaagta ttgggagtga
    17281 atgtttcaaa atcatgggtt tctataatgg tcaggctggc atttgctaga ccgccatctt
    17341 tacgaagaag tggttcttta tagcctagga gagtacgaag actggcagta agattggcgc
    17401 cgtgtccgac aattagaata cgttcagctg gactatcttt taatgatttg ataaattgga
    17461 tggtccgttg agttgtacta tagagggatt cggctccgaa cattcgagtg tcaaattgag
    17521 caagatttga acgaaaagcc tggatttgtt gcgggtaaat agcttccaag gttgcaattt
    17581 tcaaaccttc taacttccca agttgccatt cacggagatt aggaacgatt tctaaagaac
    17641 agggggtata gagttgactt tggataatct cagcagattt gaccgctcga ggtaaatcac
    17701 ttgaataaat ctgatcaaaa ggaatttcct tgagatactg accaagtcgt tttagggttt
    17761 caatggattc aggaagaaga ggagaatcac cactagcacc ttgaaaacga ccttcttggt
    17821 tccagagggt acgaccgtgg cggacaaagt agagtttcat tacttgatgt cctccaaaat
    17881 atctacaaag tctgccttta caaagctagc caagtcttgt ggcgcgacga taatgctgtg
    17941 tccgacttcg cctgcagaga caatcatttg atccaaatct agagcaattt tatcgataaa
    18001 aatgggataa ttgtgtttct gacgaattcc gacaggatta ttggctccat gaatgtaacc
    18061 agttgttttt tctaagtcct tttgtggaat catgctcact tttttattgc cagaaatttt
    18121 agctagtttc ttttcagaca agtgctgagt gatagggaca attccgataa tcggtccggt
    18181 cttgtctccc aaaagcgcca aggttttgaa aatctgatct cgttcataac cttgaggaag
    18241 ctctccttct agggcattga tttgaatccc ctgatgaggg atagctgctt tagataggat
    18301 ttgttccacc aatgtttttt tgattttaac tttttttgcc attatttata tttatcctcc
    18361 aattgactca tccaaatacc aagccagatt cccagcgcaa agaagaaggc gatgatgaca
    18421 taaccgacaa gtgaaagtcc tgtgtattgg atactttcag cgtttcctgc atttggaatt
    18481 aagatcaaaa gggtacttga taggacgata ccgatgatga aatgatagac gtgtgagtgg
    18541 tagttgttta aggcataatc catcaatttt gaaaaaacga tgagagttgc acctgcacca
    18601 attccaatcg gaaagaaggt tcccaagaga tcaaaagttt taaaaccagt caacatagga
    18661 gcatagagtc ccaaaatcaa aagtaagttc gatgggctga ggccaggaac caagacgcca
    18721 agggccaata gtgcgcctgc taggacgaag ttaagaaagc tggcgcttaa ggttccaacg
    18781 acaaaattta aggcatagag tcctaatcca gaaatgataa aggttgtcca taaccaagct
    18841 aaatcaatct tgtctcggtc agattctcga gttgattctt tgaggaggct aggaactgta
    18901 ccgataatag ctcccgcaaa gctccataat acaaaaacct gataattttc aagcaggtat
    18961 tcaatcgggt aggaaaataa gccgattccc agaagcatac cgatggcaac tggaataaag
    19021 tacaaaacat tttctttaaa gtctttaaag ggatgggcca gaaagccaat cattcgttca
    19081 tagattccta agattgctgc tagaacccct ccggaaattc ccggtaggat aaatccaaga
    19141 gcaattacaa tccctttaat aacgcgtgct aaccatgaga gcatatattt cctccaacta
    19201 tttctatttc aaaaaatcct tactatattg tatcacaatc agacacaaaa agaaaaagca
    19261 aatgataaac aaatgctttt aaggttttaa aaaaagtttt cgaaaggttt cttctttatt
    19321 ttttaaggga gagataacgt tgatatctaa atcgtggtca aagccagcaa tttttccttt
    19381 agatgtgtat tggtgaatat cataatctaa atcagtttta ggactgctct ccaaaaatcc
    19441 tgagtctgag ccgtaggacg gaatccaaac agaggtaaac ttgcctgtat caatactgtg
    19501 ttcttccatg aagtagacac caacgtagat gccgatgttt ttagcaccta gtgatgctag
    19561 ttttgctcga aagttttcga caccttcgtt catattagac atggttttgt cttccacgtc
    19621 aagccaatag taactagggc tgtaaggaga ggcagcattg tagaaaactt cggcagcctt
    19681 ttccatttct tggacacttt ttccagctac ataagcgtag acagcaactg ggacattccg
    19741 cttttgaagt tcagtgatat gactcttata ggccttgtct attccattga taaatgaagc
    19801 atcattttct tttgttgttt gagcaccact gtgaacacga acaatagcac ctgaaatatt
    19861 ttgtgagagg gcatcgtagt tgatttcctc aggacgctgc cagccagaga ggtcaataat
    19921 cggtttgtct aagtgtttca aagcctgtgc ttcaatctgt gctatattgg attttgtttt
    19981 aaacgattgg ctgtcattaa gtgggcgatt gatgattaaa atgaacatca taatcccaaa
    20041 aaaactaaat aaaataagtg gatgaatttg ttttctcata tcttataatt ctaccctaaa
    20101 aatcaaaaaa aatcaaaaaa atgggttaag gaagagactt tagagcattt tttcattcaa
    20161 gagtgcggaa tgatttgaaa tatggtataa taaaagggaa tttctacaga aaagagaaga
    20221 ttatgtcaaa ttttgccatt attttagcag cgggtaaagg gactcgcatg aaatctgatt
    20281 tgccaaaagt tttgcacaag gttgcgggta tttctatgtt ggaacatgtt ttccgtagtg
    20341 tgggagctat ccaacctgaa aagacagtaa cagttgtagg acacaaggca gaattggttg
    20401 aggaggtctt ggctgaacag acagaatttg tgactcaatc tgaacagttg ggaactggtc
    20461 atgcagttat gatgacagag cctatcttag aaggtttgtc aggacacacc ttggtcattg
    20521 caggagatac tcctttaatc actggtgaaa gcttgaaaaa cttgattgat ttccatatca
    20581 atcataaaaa tgtggccact atcttgactg ctgaaacgga taatcctttt ggctatggac
    20641 gaattgttcg taatgacaat gctgaggttc ttcgtattgt tgagcagaag gatgctacag
    20701 attttgaaaa gcaaatcaag gaaatcaaca ctggaacata cgtctttgac aacgagcgtt
    20761 tgtttgaggc tttgaaaaat atcaatacca ataacgctca aggcgaatac tatattacag
    20821 acgtcattgg tattttccgt gaaactggtg aaaaagttgg cgcttatact ttgaaagatt
    20881 ttgatgaaag tcttggggta aatgaccgtg tggcgcttgc gacagctgag tcagttatgc
    20941 gtcgtcgcat caatcataaa cacatggtca acggtgttag ctttgtcaat ccagaagcaa
    21001 cttatatcga tattgatgtt gagattgctc cggaagttca aatcgaagcc aatgttatct
    21061 tgaaagggca aacgaaaatt ggtgctgaga ctgttttgac aaacggtact tatgtagtgg
    21121 acagcactat cggagcagga gcggtcatta ccaattctat gattgaggaa agtagtgttg
    21181 cagacggtgt gacagtcggt ccttatgctc acattcgtcc aaattcaagt ctgggtgccc
    21241 aagttcatat tggtaacttt gttgaggtga aaggatcttc aatcggtgag aataccaagg
    21301 ctggtcattt gacttatatc ggaaactgtg aagtgggaag caacgttaat ttcggtgctg
    21361 gaactattac agtcaactat gacggcaaaa acaaatacaa gacagtcatt ggaaacaatg
    21421 tctttgttgg ttcaaattca accattattg caccagtaga acttggtgac aattccctcg
    21481 ttggtgctgg ttcaactatt actaaagacg tgccagcaga tgctattgct attggtcgcg
    21541 gtcgtcagat caataaagac gaatatgcaa cacgtcttcc tcatcatcct aagaaccagt
    21601 aggagcctat catggagttt gaagaaaaaa cgcttagcag aaaagaaatc tatcaaggac
    21661 caatatttaa actggtccaa gatcaggttg aattaccaga aggcaaggga actgcccaac
    21721 gggatttgat ttttcacaat ggggctgtct gtgttttagc agtaacggat gaacaaaaac
    21781 ttatcttggt caagcagtac cgcaaagcta tcgaggcagt ctcttacgaa attccagccg
    21841 gaaaattgga ggtaggagaa aacacagccc ctgtcgcagc tgcccttcgt gaattagagg
    21901 aagaaacagc ctatacaggg aaattagaac tcttgtacga tttttattca gctattggct
    21961 tttgtaatga gaagttaaaa ctatatttag caagcgattt gacaaaagtg gaaaatccgc
    22021 gtccgcagga tgaggatgaa accttggaag tccttgaagt gagcttagaa gaagcgaaag
    22081 aattaatcca atcaggtcat atctgtgatg ccaagacaat tatggctgtt cagtattggg
    22141 agttgcagaa aaaatagagg aggtcagtat gggtaaatct ttattaacgg atgaaatgat
    22201 tgaaagagct aatagaggcg aaaaaatttc aggtcctcct ttgctagatg ataatgagga
    22261 aactaagatt ttaccaacct cttcttcccg ttttggttat gccaatccta aggatcatgg
    22321 ttttagccag gaaaccttga agattcaggt cgaaccatct attcataaaa gccgtcgtat
    22381 tgaaaatacc aagagaaatg tcttcaattc taagttgaat aaaatcttat tcgcggtcat
    22441 ctttctcttg attttgcttg ttttagcaat gaaacttttg taatagaaaa ggaattgaaa
    22501 tgaaaatagg aattattgct gctatgccag aagaactggc ttatctggtc cagcatttag
    22561 acaatgccca ggagcaagtt gttttgggga atacctatca tacaggaacc attgcttctc
    22621 atgaagtcgt tcttgtagaa agtggaattg gtaaggtcat gtctgctatg agtgtggcga
    22681 ttttggctga tcatttccag gtggatgccc ttattaatac gggttcagct ggggcagtag
    22741 cagaaggtat cgctgttggg gatgtcgtga ttgctgacaa attagcctat catgacgtgg
    22801 atgtcacagc ttttggctat gcttatggac aaatggcgca acaaccgctt tatttcgaat
    22861 cagacaaaac ctttgttgct caaatccaag agagtttatc tcaattggac caaaactggc
    22921 atcttggttt gattgctaca ggagatagtt ttgttgcagg aaatgacaag atagaagcga
    22981 ttaagtccca tttcccagaa gttttagccg tggagatgga gggggcagct attgctcaag
    23041 cagcgcatgc cctcaatctc ccagtcttag tcatcagagc tatgagtgac aatgccaacc
    23101 atgaagcaaa catctttttt gatgagttta ttatcgaagc tggacgtcgc tctgcccaag
    23161 tcttgttgac ctttttgaag gctttagatt aagtggaaat ttgacagttt ttctagctta
    23221 tgataagatt taagtaaaga aaagctagaa aacgtttcag aggatattat gagtattgaa
    23281 atgaccgtca gtgagattgc agaggtctta ggattatctc gccaagcaat caataaccgt
    23341 gtcaaagaat taccagaaga agacacagat aaaaatgaca aaggggtaac agttgttacc
    23401 agaagtggct tgattaagct agaagaaatc tataaaaaaa cgatttttga agatgaacct
    23461 gtcagtgaag atgtcaaaca acgtgaactg atggagattc tagtggatga gaagaatgca
    23521 gaaattcttc gtctttatga acaattaaaa gccaaggatc gtcagttatc agaaaaagac
    23581 gagcagatgc gtatcaaaga ccgtcagatt gctgagaaag acaaacaatt agatcagcaa
    23641 caacaattga cccttcaagc catgaaggat caagaaaatc ttaagctaga gctggaccaa
    23701 gcaaaagaag aagtccaatc cactaaaaaa ggcttttttg ctcgtttatt tggaggataa
    23761 tcaaggagct gtttaggtta aatgctaacc tgatggcttc ttttgtttgt gaatagtata
    23821 gttgattaga acagagacag tagaggagag gtacagaatg gaacgattag aagattacat
    23881 tgcttttgat ttagaattta atcagcatga aggacaaaca cacttgattc aagtatcggc
    23941 agtgcgtttt agagatggtc gggaaatcga tgcctatgat tcctatgttc ataccagcgt
    24001 ccctctaaaa agctttatca atggtttgac cgggattaca gctgagacct taaaagatgc
    24061 tcctccagtt gagaaagtct tagaagaatt ccaagagttt gtgggttctt tgctgatgat
    24121 aggctacaat gctgctaaaa gtgatttacc tattttagca gagcatggtt tagactatag
    24181 ccaacagtac aaggtggatt tgtatgatga agcttttgaa cgtcggagtt cagatttaca
    24241 tggtattgcc aatctcaaat tgcaaactgt tgcctcattt cttggatttc aaggtcagtc
    24301 tcataatagt ttagaggatg ctcggatgac ggcgcgtgtt tacgaatcct tcttagagtc
    24361 ggatcaagct agggaattgt tagagacaga aagtagctta tcaaacaatc cttttggtgg
    24421 cttggacttg tctcaattat ttgactagga gtgcctatga aacctgaaaa acctaaaaaa
    24481 ttgggtctta aacagattta cctcaatctt gataaaatcc tctttctatt tttcttgatt
    24541 tttatgatag tggagtattt gtgggtacca ttcaattcat ggttggctag cttcttatta
    24601 gatcagacag gttatctttt tatttcctat aacaatgtct tagccatcct tactcattct
    24661 ccattgatta gtctagcttt tttagccttg attgtaatta actttctggt tgcttatttt
    24721 caaataggac tcctctttat tggtgctcgt catctcctct ataatgaaaa gcgaaggcta
    24781 attgagtata tccgcaaggt tttccatgaa agttttgaat ttatgaaaaa gctaactggc
    24841 gctaaagcct tgtttatctt tttctatata gctatgctgt ttccttttat acggaaaatg
    24901 ctgaagattt attatcttaa taaaatcgtc attccagagt ttatccaagc ttatttagaa
    24961 gataaatatt ggatgtggtg gctgagcatc ctacttctat ctcttatctt tctctatgtc
    25021 tctgtcagat tgatgtttgc ccttccgaag attgtatatg atcagctgac tgttcgagaa
    25081 gcagtgatgt ttagcttgga gaaaaccaag aagagagtta ctttttatgc ttggaattta
    25141 ttttacatct tgctcaaagc acatttatta ttttatcttc ctttgattcc tttattattg
    25201 gctcaaactt tggtagatga tatcactcag agagagtctc tgattcttgg tattttgaat
    25261 tttgttgtga ttaaaaatct ctattatatg gctctgactt attttttggt taaatttgtt
    25321 tcatttttga caggaaagga gctggatatg cttcctagga gagaaaaaga tcacatcgtg
    25381 cgatggggtg tcatgacttg tgccagtctt ttctttgcct tagaaggtta tatttatctg
    25441 gaggctccca tggttcatct acctcaactt atttctcacc gaggggtttc caatgcaaat
    25501 gggattcaaa atacagtaga gtccttggaa actacagcac aactcaaacc agacttggtg
    25561 gagacggacg tgcaggaaac aaaagatggg cagtttgtca tgatgcatga tgctaacttg
    25621 aaaaatctag caggtatcaa taaaagtcct caagacttaa acttggagga gcttaaaggg
    25681 attgatattt ttgaaaatgg ctaccagact aaaatttcaa gctttgaaga ttatctcagt
    25741 cgagccaacg aacttggtca aaaattacta attgaaatta aaaccagtaa aaaagatagt
    25801 ccagacatga tggaccgctt tttagcccgt tatgctgcaa agctcaagat ttatggacat
    25861 caaatccagt ctttagacta ccatgttgtc gaaaaagtaa gacagtatga tgccgaactg
    25921 ccagtttatt tcatcatgcc ctacaattct gtctttccta aaacaagagc gacaggatat
    25981 actatggagt actcaacctt ggatgaatat tttgtaagca aactatggac aacggatcag
    26041 aaactttatg tctggactgt caatgattca gaagctatca gcaaatctct tcacttagga
    26101 gtagatggag tgattacaga tgatttggaa aaagttcagc gggaaataga agtagcccaa
    26161 gaagatccag aatatacgga tttgctcttg aaaaaagcat tggaattctt tgaattttag
    26221 taataaaaaa gaggaacggt tgttcctccc atgataggta agtattcttg tgaatgcttg
    26281 cttttttgtg gttgcaatcc gtttacgaga attgtttgta ttgttcttgt ttcaatttac
    26341 tttatagtgc tttgaagttg gaatgctaca ctataacttc taaaatatag tgaaatgaac
    26401 caaaaatagt acacaatgtg gtataatctt cttatggcat attcaataga ttttcgtaaa
    26461 aaagttctct cttattgtga gcgaacaggt agtataacag aagcatcaca cgttttccaa
    26521 atctcacgta ataccattta tggctggtta aagctaaaag agaaaac
//
LOCUS       DBERDS010000024        26304 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.024, whole genome shotgun sequence.
ACCESSION   DBERDS010000024 DBERDS010000000
VERSION     DBERDS010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.024"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..116
                     /locus_tag="ACL73E_001201"
     CDS             <1..116
                     /locus_tag="ACL73E_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS0801173.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="ACL73E_001202"
     CDS             135..1652
                     /locus_tag="ACL73E_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS0801174.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTSGRGEEVDSKEISESADSTSNIADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="ACL73E_001203"
     CDS             1777..3105
                     /locus_tag="ACL73E_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0801175.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3357..4223
                     /locus_tag="ACL73E_001204"
     CDS             3357..4223
                     /locus_tag="ACL73E_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0801176.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4239..5078
                     /locus_tag="ACL73E_001205"
     CDS             4239..5078
                     /locus_tag="ACL73E_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0801177.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="ACL73E_001206"
     CDS             5351..5803
                     /locus_tag="ACL73E_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS0801178.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="ACL73E_001207"
     CDS             5900..6244
                     /locus_tag="ACL73E_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801179.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVRLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     HDKIPNNGRINF"
     gene            6254..6448
                     /locus_tag="ACL73E_001208"
     CDS             6254..6448
                     /locus_tag="ACL73E_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801180.1"
                     /translation="MKALCIFLLYMLAWTVLAMIIRGGLDGFDEHTWRNILASALSSL
                     YIHYISIDRKRKKSKRKKKK"
     gene            6531..7175
                     /locus_tag="ACL73E_001209"
     CDS             6531..7175
                     /locus_tag="ACL73E_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGS0801181.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7344..8261
                     /locus_tag="ACL73E_001210"
     CDS             7344..8261
                     /locus_tag="ACL73E_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGS0801182.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKDKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8279..9163
                     /locus_tag="ACL73E_001211"
     CDS             8279..9163
                     /locus_tag="ACL73E_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGS0801183.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9179..10030)
                     /locus_tag="ACL73E_001212"
     CDS             complement(9179..10030)
                     /locus_tag="ACL73E_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGS0801184.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDGNCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10230..12287
                     /gene="pbp2b"
                     /locus_tag="ACL73E_001213"
     CDS             10230..12287
                     /gene="pbp2b"
                     /locus_tag="ACL73E_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGS0801185.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12298..12894
                     /gene="recR"
                     /locus_tag="ACL73E_001214"
     CDS             12298..12894
                     /gene="recR"
                     /locus_tag="ACL73E_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGS0801186.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13070..14113
                     /locus_tag="ACL73E_001215"
     CDS             13070..14113
                     /locus_tag="ACL73E_001215"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGS0801187.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14197..15570
                     /gene="murF"
                     /locus_tag="ACL73E_001216"
     CDS             14197..15570
                     /gene="murF"
                     /locus_tag="ACL73E_001216"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGS0801188.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAYLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGNQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            15557..16168
                     /locus_tag="ACL73E_001217"
     CDS             15557..16168
                     /locus_tag="ACL73E_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGS0801189.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEGSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDINRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPVLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            16259..16963
                     /locus_tag="ACL73E_001218"
     CDS             16259..16963
                     /locus_tag="ACL73E_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGS0801190.1"
                     /translation="MNLWDIFFTTQATKPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIVKEA"
     gene            17182..18555
                     /gene="ftsA"
                     /locus_tag="ACL73E_001219"
     CDS             17182..18555
                     /gene="ftsA"
                     /locus_tag="ACL73E_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGS0801191.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18572..19831
                     /gene="ftsZ"
                     /locus_tag="ACL73E_001220"
     CDS             18572..19831
                     /gene="ftsZ"
                     /locus_tag="ACL73E_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGS0801192.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19836..20507
                     /locus_tag="ACL73E_001221"
     CDS             19836..20507
                     /locus_tag="ACL73E_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGS0801193.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYIGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20517..21056
                     /locus_tag="ACL73E_001222"
     CDS             20517..21056
                     /locus_tag="ACL73E_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGS0801194.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21056..21319
                     /locus_tag="ACL73E_001223"
     CDS             21056..21319
                     /locus_tag="ACL73E_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGS0801195.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21316..22101
                     /locus_tag="ACL73E_001224"
     CDS             21316..22101
                     /locus_tag="ACL73E_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGS0801196.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            22110..22898
                     /gene="divIVA"
                     /locus_tag="ACL73E_001225"
     CDS             22110..22898
                     /gene="divIVA"
                     /locus_tag="ACL73E_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGS0801197.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23246..26038
                     /gene="ileS"
                     /locus_tag="ACL73E_001226"
     CDS             23246..26038
                     /gene="ileS"
                     /locus_tag="ACL73E_001226"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGS0801198.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEYGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT         7912 a         4813 c         5795 g         7784 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagggggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttag taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgaaac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgattt ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccat
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gtcaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatattgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgagt accttgtaaa cgggtttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac actttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cagatgcttt gaaagccttc
     3061 actgaaaaag cgaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 taaaaagtag ttttttaaag aacctaagag tgtatacccc cttttccctc tacacagata
     3181 gtgtaagaaa agggggcttt tgtttaaaat gtaagaaact gtcacgaaat taaaatgaag
     3241 ttcttacata agcgaaccat aaaaaatttc attttgattt taaaacagtt caagaaagtc
     3301 aaaaaattat tctatttgaa agagaggtgc cgactgtgaa agtcaataaa atccgtatgc
     3361 gggaaacagt gatttcctac gctttcctag caccagtatt attcttcttt gtcatctttg
     3421 tgttggctcc gatggtgatg ggcttcatta caagtttctt taactactca atgactaaat
     3481 ttgagtttgt gggcttagat aactatatcc gtatgtttaa agatcctgtc tttacaaaat
     3541 ctctgattaa cacagttatt ttggttattg gatctgtacc agttgttgtt ctattctcac
     3601 tctttgtagc atctcagacc tatcatcaaa atgtcattgc cagatccttc taccgtttcg
     3661 tcttcttcct tcctgttgta acgggtagtg ttgccgtgac agttgtttgg aaatggattt
     3721 atgacccgct atcagggatt ctaaactttg tccttaagtc aagccacatc atcagccaaa
     3781 acatttcttg gttgggagat aaaaactggg cattgatggc gattatgatt attctcttga
     3841 ccacttcagt tggtcagccc atcatccttt atatcgctgc catggggaat attgacaatt
     3901 cactggttga agcggcgcgt gttgatggcg caactgagtt tcaagttttt tggaagatta
     3961 aatggccaag ccttcttcca acaactcttt atattgcaat catcacaaca attaactcat
     4021 tccagtgttt cgccttgatt cagcttttga catctggtgg tccaaactac tcaacaagta
     4081 ccttgatgta ctacctttac gaaaaagcct tccaattgac agaatacggc tatgccaaca
     4141 caattggtgt cttcttggca gtcatgattg ctatcgtaag ctttgttcaa tttaaagtac
     4201 ttggaaacga cgtagaatac taaagaaagg agacagctat gcaatctaca gaaaaaaaac
     4261 cattaacagc ctttactgtt atttcaacaa tcattttgct cttgttgact gtgctgttca
     4321 tctttccatt ctactggatt ttgacagggg cattcaaatc acaacctgat acaattgtta
     4381 ttcctcctca gtggttccct aaaatgccaa ccatggaaaa cttccaacaa ctcatggtgc
     4441 agaaccctgc cttgcaatgg atgtggaact cagtatttat ctcattggta accatgttct
     4501 tagtttgtgc aacctcatct ctagcaggtt atgtattggc taaaaaacgt ttctatggtc
     4561 aacgcattct atttgctatc tttatcgctg ctatggcgct tccaaaacaa gttgtccttg
     4621 taccattggt acgtatcgtc aacttcatgg gaatccacga tactctctgg gcagttatct
     4681 tgcctttgat tggatggcca ttcggtgtct tcctcatgaa acaatttagt gaaaatattc
     4741 ctacagagtt gcttgaatca gctaaaatcg acggttgtgg tgagattcgt accttctgga
     4801 gtgtagcctt cccgattgtg aaaccagggt ttgcagccct tgcaatcttt accttcatca
     4861 atacttggaa tgactacttc atgcaattgg taatgttgac ttcacgtaac aatttgacca
     4921 tctcacttgg ggttgcgacc atgcaggctg aaatggcaac caactatggt ttgattatgg
     4981 caggagctgc ccttgctgct gttccaatcg tcacagtctt ccttgtcttc caaaaatcct
     5041 tcacacaggg tattactatg ggagcggtca aaggataata ctctgcgaaa atcgaatgca
     5101 aactacgtca gcttcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tatcaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actacctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctgataga
     5581 agggcatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgagtgac attggctttg ttcattgtca tgaacactac ccgctcttgt tgggttatca
     5701 caattttgcg attttcttcc caggtgagcc acatcagcca aatggttatg caggcatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat cttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgataa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagtatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aggggcattg tgaatggatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatggcgcg
     6061 ctcgatctta agtagggcag ctgcaactgc ggcagcaaga gtaagattat tgactaagat
     6121 ttttggatgg attttacgaa tagctgtgct cgcagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcacatga taaaatccct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg tatatgttag cttggacagt
     6301 gcttgcaatg ataatccgtg gagggctaga tggatttgat gaacacactt ggcgtaatat
     6361 tttagctagt gcgttgtcct cgctatacat acattatata tccatagata gaaaaagaaa
     6421 aaagtccaaa agaaaaaaga aaaaatagat ttgttcatgg tagggactta tgaaagcttt
     6481 actaacaaaa aagaaaacag tttacaaaga aaaatgatgg aggagcaaac atggcacaaa
     6541 aaggagtaag ccttatcaag gcagcatttg atacagataa ctttctcatg cgttttagtg
     6601 agaaagtctt ggacatcgtg acagccaatc ttctttttgt cgtctcttgt ttgcccatcg
     6661 tgacgattgg agtggctaaa atcagcctct acgagaccat gttcgaagtt aagaagagca
     6721 gacgggtgcc tgtttttaaa atctatctaa gatctttcaa gcaaaatctg aaactaggtc
     6781 ttcagctggg tttaatggag ttaggaattg tgtttcttac cctttcagat ctctatcttt
     6841 tctggggtca aacagctctg cccttccaat tgctgaaagc catttgtcta ggcattctga
     6901 ttttccttac gattgtgatg ttggctagct atccaatcgc ggcacgttat gatttaactt
     6961 ggaaagaagt gttacaaaaa gggcttatct tggctagttt taactttcct tggttcttcc
     7021 tcatgttagc cattcttgtc ctcattgtga tggttcttta tctgtccgcc ttcagtctac
     7081 tcttaggtgg ctcagtcttc ctactttttg ggtttggact attggtcttt atccagactg
     7141 gattgatgga gaaaattttc gcaaaatacc aataggagcc ttatttctga aactactttc
     7201 aaaggctcca aacgctattc tataagcgag aaactaaaat ctaagtgtct ataagatatt
     7261 gaaagccttt tcggtaaagt gtatactaaa gaagtaaaga aaaatctgct ttagcagaaa
     7321 ataaaaataa taggagaaaa tctatgtcag atttgaaaaa atacgaaggt gtcattccag
     7381 ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg cgtgccttgg
     7441 ttcaatactt cattgataaa ggtgttcaag gtctttatgt caatggttct tctggtgaat
     7501 gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg gcggtagcca
     7561 aagataaatt gaccattatt gcccatgttg cttgcaataa tactaaagat agtatggaac
     7621 ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca ccaatttatt
     7681 tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct gcagctccaa
     7741 acacagacta cgtgatttac aacattcctc aattggcagg ggttgctttg actccaagcc
     7801 tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct tctatgccag
     7861 ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc tttaatggtc
     7921 ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc ggtggtactt
     7981 atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat aaggacctag
     8041 aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc acttctgctc
     8101 atggaaatat gtacggtgtc atcaaagaag tcttgaaaat caatgaaggc ttgaatattg
     8161 gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt gtagaagcgg
     8221 ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atctaaaagg aggtatttat
     8281 gacatattac gttgcaattg atatcggtgg aaccaacatc aagtatggtt tggttgatca
     8341 agaggggcaa cttcttgaat cgcatgaaat gccaactgag gcgcataagg gtggacctca
     8401 tatcttacaa aagaccaaag atatcgtagc tagttattta gaaaaaggcc cagtagcagg
     8461 tgttgccata tcttctgctg ggatggtgga tccggataag ggtgagattt tctatgctgg
     8521 gccgcaaatc cctaactacg caggcaccca gttcaaaaag gaaatcgaag aaagctttac
     8581 tattccttgt gagattgaaa atgatgtcaa ctgtgcaggt cttgctgagg cagtatctgg
     8641 ttcaggcaag ggagcaagtg tgacactttg cttgaccatt ggaacaggta tcggtggttg
     8701 cttgattatg gataggaaag tcttccatgg ttttagcaat tcagcctgtg aagtcgggta
     8761 tatgcatatg caggatggag cttttcagga tctcgcttct acaacagctt tagtgaaata
     8821 tgtagctgaa gcccatggag aagatgttga tcagtggaat ggccgacgta tctttaagga
     8881 agctactgaa ggaaacaaaa tctgcatgga aggcattgac cgtatggttg actatctagg
     8941 aaaaggtctg gcaaatattt gctacgttgc caatccagaa gtggttattc ttggtggtgg
     9001 tatcatgggg caagaggcta tcctcaaacc taagatccgc acagccttga aagaggcttt
     9061 ggtaccaagt ttagcagaaa aaacacgatt agaatttgcc catcaccaaa atacagcagg
     9121 gatgttgggt gcatattatc attttaagac aaaacaatcc tagtttggct cagccaaact
     9181 aggattttct tacacgtttt tgtctacgat agccgttgag ttttttattt tcccagtagc
     9241 tattaaagat tttttccttg ctttcgcgat tgatttccaa aaagtaggca taaatcaaat
     9301 cgataaagaa gagcatagga agttgagcgg atattcgttg gatataggag ggttggctgt
     9361 gggtggctac aagaacagtc tctgtatagg tctggctatc tttattggga acacttgtaa
     9421 agagtacagt ctttgccccc atctccttgg catctaatag actatctaaa atagaaggag
     9481 ttgagcctga aagtgagaag cccagtacta gacaatttcc atccatgatg ctggttgtcc
     9541 aggcaaagcc gtcttggtct gtcaaagctt cgcagaccac acctagtcgc ataaaacgta
     9601 atttcatttc acgggcgacg aggccagaac tccctgttcc aaagaagtag atacgctcag
     9661 catcttcgat tagctgggca attcgctcta gttggatttc gtcaatcaag tcttgtgttt
     9721 gttccctcat attgctataa cttctgagga ctcgtttggt cagtggactg tgcttggaga
     9781 cttggttggc ttgattttct gcctgatgtt ggtattggaa aataaattct cggtagccag
     9841 taaagccaca ctttttagca aagcgggtca aagcagcttg agaaatatgt aatttttggg
     9901 tgacttgttg agaagataaa tcatctgtaa tcgtttcagc ttgcaaaaaa tagcgagcga
     9961 tttcttgctc taggtctgtc atttcttcaa aatgtgaatc aatgatagtt gcgatatctg
    10021 gtttgtccat agggaaagct cctttacatg agtcatactg gaagactaga tcagggaata
    10081 gtcacacttc attataacac ataatataag gatagataaa taaaaacgca tttctgtttt
    10141 aaaaacgaaa aaatcgaaaa agcttctttc ttttccataa ttttctactc aaattgtggt
    10201 acaattaaga gtaagatttt aagttagaaa tgagactgat ttgtatgaga aaatttaaca
    10261 gccattcgat tccgattcgg cttaatttat tgttttcaat cgtcatttta ctctttatga
    10321 ccattattgg tcgtttgttg tatatgcagg ttttgaacaa ggatttttac gaaaaaaagc
    10381 tagcctcagc tagtcagacc aagattacaa gcagttcagc ccgtggggaa atttatgatg
    10441 ctagtggaaa acctttggta gaaaatacgt taaagcaggt tgtttccttt acgcgtagca
    10501 ataaaatgac ggctacagac ttaaaagaaa cagctaaaaa gttactgact tatgtgagca
    10561 tcagttctcc aaatttgaca gaacgccagc tggcggatta ctatttggct gatcctgaaa
    10621 tctataaaaa aacagtggaa gctctcccaa gtgagaaacg cttggattca gatggcaatc
    10681 gtctatccga atcagaactg tataacaatg cggtcgatag tgtccaaaca agtcaactaa
    10741 actatacaga ggatgaaaag aaagaaatct atctttttag tcagttaaat gctgttggaa
    10801 actttgcgac aggaaccatt gctacagatc ctctaaatga ttctcaggtg gctgttattg
    10861 cctctatttc aaaggagatg cctggcatta gtatttctac ttcttgggat agaaaggttt
    10921 tggaaacttc cctttcttct atagttggga gtgtatccag tgaaaaagct ggtctcccag
    10981 cggaagaagc agaagcctat cttaaaaaag gctattctct aaatgatcgt gtaggaacct
    11041 cctatttgga aaagcaatat gaagagacct tacaaggaaa acgctcggta aaagaaatcc
    11101 atctggataa atatggcaat atggaaagcg tggatacaat tgaggaaggt agtaagggaa
    11161 acaatatcaa actgaccatt gatttggctt tccaagatag cgtggatgct ttactgaaaa
    11221 gttatttcaa ttccgagcta gaaaatggtg gagccaagta ttctgaaggt gtctatgcag
    11281 tcgcccttaa cccaaaaaca ggtgcggttt tgtctatgtc agggattaaa catgacttga
    11341 aaacgggaga gttgacgcct gattccttgg gaacggtaac caatgtcttt gttccaggtt
    11401 cggttgtcaa ggcggcgacc atcagctcag gttgggaaaa tggagtcttg tcaggaaacc
    11461 agaccttgac agaccagtcc attgtcttcc aaggttcagc tcccatcaat tcttggtata
    11521 ctcaggctta cggttcattc cctatcacag cggtccaagc tctggagtat tcatcaaata
    11581 cctatatggt ccaaacagcc ttaggtctta tggggcaaac ctatcaaccc aatatgtttg
    11641 tcggcaccag caatctagag tctgctatgg agaaactgcg ttcaaccttt ggcgaatatg
    11701 gcttgggtac tgcgacagga attgacctac cagatgaatc tactggattt gttcccaaag
    11761 agtatagctt tgctaattac attactaatg cctttgggca gtttgataac tatacgccga
    11821 tgcagttggc tcagtatgta gcaactattg caaataatgg tgttcgtgtg gctcctcgta
    11881 ttgttgaagg catttatggt aataatgata agggaggact gggtgacttg attcagcaac
    11941 tgcaaccgac agagataaat aaggtcaata tatccgactc cgatatgagc atcttgcacc
    12001 aaggttttta tcaggttgcc catggtacta gtggattgac aactggacgt gccttttcaa
    12061 atggcgcctt ggtatccatt agcggaaaaa caggtacagc cgaaagctat gtggcagatg
    12121 gtcagcaagc aaccaatacc aatgcggtgg cctatgcccc atctgataat ccccaaatcg
    12181 ctgttgcagt ggtctttcct cataatacca atctaacaaa tggtgtagga ccttccattg
    12241 cgcgtgacat tatcaatctg tatcaaaaat accatccaat gaactagaaa ggaaattatg
    12301 ctttatccaa cacctattgc caagttgatt gacagttatt ctaagttacc aggtatcggg
    12361 attaagacgg ctacgcgtct ggccttttat acgattggga tgtctgctga tgatgtcaat
    12421 gaatttgcaa aaaatctcct ttctgctaag agagaattga catattgttc tatttgtgga
    12481 cgtttgacag acgacgatcc ttgttctatc tgtactgatc cgactcgtga ccagacaaca
    12541 attttagttc ttgaggatag tagagatgtg gcagccatgg aaaatatcca agaataccat
    12601 ggactctatc atgtccttca tggcctcatt tctcctatga atggtatcag tccggacgat
    12661 atcaatctca agagccttat gactcgtctt atggatagtg aagtttcaga agtgattgtg
    12721 gcgactaatg ctacagcgga tggtgaagcg acttccatgt atctttcacg tttgctcaag
    12781 ccggctggta tcaaggttac gcgtctagca cgaggtctcg ctgtgggagc ggacattgag
    12841 tatgcggacg aagtgacact cttacgagcg attgaaaatc ggacagagtt gtaagtgtag
    12901 gcaaatttac gaactccatt catttataaa aaatcaaaga ggctgaaaat cgttcctatc
    12961 ggcctctttt tgtatagtgt gatgagtagg atcaggttca agttttaaaa aaccaagcaa
    13021 atatgatata ctaaagagcg agtattctag tagaattagg acaaataata tgaaacaaac
    13081 gattattctt ttatatggtg gacggagtgc ggaacgcgaa gtctctgtcc tttcagctga
    13141 gagtgtcatg cgtgcggtca attacgaccg tttcacagtc aagactttct ttatcagtca
    13201 gtcaggtgac tttatcaaaa cacaggaatt tagtcatgct ccggggcaag aagaccgtct
    13261 catgaccaat gaaaccattg attgggataa gaaagttgca ccaagtgcta tctacgaaga
    13321 aggtgcagtg gtctttccag tccttcacgg gccaatggga gaagatggct ctgttcaagg
    13381 attcttggaa gttttgaaaa tgccttacgt tggttgcaac attttgtcat caagtcttgc
    13441 catggataaa atcacgacta agcgtgttct ggaatctgct ggtattgccc aagttcctta
    13501 tgtggctatc gttgaaggcg atgatgtgac tgctaaaatc gctgaagtgg aagaaaaatt
    13561 ggcttatcca gtcttcacta agccgtcaaa catggggtct agtgtcggta tttctaagtc
    13621 tgaaaaccaa gaagaactcc gtcaagcctt aaaacttgcc ttccgatatg acagccgtgt
    13681 cttggttgag caaggagtga atgcccgtga aattgaggtt ggcctcttgg gtaactacga
    13741 tgtcaagagc acgctacctg gagaagttgt caaggacgtt gccttttatg actacgatgc
    13801 caagtatatt gataacaaga ttactatgga tattcctgcc aaaatcagtg atgatgtggt
    13861 ggctgtcatg cgtcaaaatg cagaaacagc cttccgtgcc attggtggcc ttggtctatc
    13921 tcgttgcgat ttcttctata cagataaggg agagattttt ctcaacgagc tcaataccat
    13981 gccaggtttt acccagtggt ctatgtaccc actactttgg gacaatatgg ggatcagcta
    14041 cccagaacta atcgagcgtt tggttgacct tgccaaggaa agttttgaca agcgcgaagc
    14101 gcatttgata taaaatgaaa gagagggtag aagccagaac catcactgca cggtgactag
    14161 agttctcgga cttcagccct ttttaaagga gtagaaatga aattaacaat ccatgaaatt
    14221 gcccaagttg ttggagccaa aaatgatatc agtatctttg aggacaccca gttagaaaaa
    14281 gctgagtttg atagtcgttt gattggaact ggagatttat ttgtgccact taaaggtgcg
    14341 cgtgatggcc atgactttat tgaaacagcc tttgaaaatg gtgcagcagt aaccttgtct
    14401 gagaaagagg tctcaaatca tccttacatt ctagtagatg atgttttgac agcctttcaa
    14461 tccctagcat cctactatct tgaaaaaacg actgttgatg tctttgctgt tacaggttca
    14521 aatggcaaga caacgactaa ggatatgttg gcgtatttac tgtcaacaag atacaagacc
    14581 tacaaaacac aaggcaatta caataatgag attggccttc cttacacagt tctccacatg
    14641 cctgaaggaa cagaaaagtt ggtcttggag atggggcagg accacttggg agatattcat
    14701 ctcttgtctg aattggctcg tccaaaaaca gccatcgtga ccttggttgg agaagctcat
    14761 ttggcctttt tcaaagatcg ttctgagatt gctaaaggaa aaatgcaaat tgcagacgga
    14821 atggcttcag gttccttgct tttagcgccg gctgacccta tcgtagagga ctatttgcca
    14881 actgataaaa aggtggttcg ttttggtcaa ggagcagagc tggaaattac tgacttggtt
    14941 gagcgcaaag atagtctgac cttcaaggcc aatttcttag agcaagtcct tgatttgcca
    15001 gtaactggca agtataatgc gacaaatgct atgattgcat cctatgttgc cttgcaagaa
    15061 ggagtttcag aggagcaaat tcatcaggcc ttccaagatc ttgaattgac gcgtaaccgt
    15121 accgaatgga agaaagcagc caatggagca gatatcctgt ctgatgtata caatgccaat
    15181 ccaactgcta tgaagttgat tttagagact ttctctgcca ttccagccaa tgaaggtggc
    15241 aagaaaattg cggttttagc ggacatgaag gaactgggta accagtcagt tcaacttcat
    15301 aatcagatga ttttgagcct ttctccagat gtgcttgata ccgtgatttt ctatggagaa
    15361 gacattgctg aattagccca attggccagt caaatgttcc caattggcca cgtttactac
    15421 ttcaagaaaa cagaagacca agaccaattt gaagacctag tcaagcaggt caaggaaagc
    15481 ctcagtgcca atgatcaaat cttgctcaag ggctctaact ctatgaacct agctatgttg
    15541 gtagaaagtt tagaaaatga aaccaagtga ttttgttaag tatctgcaaa gaatgattgc
    15601 ccttacagat actggcttaa cctttacaaa agatcctttt gaccgtgagc gctacgagga
    15661 cttgcgaagt ctgttatctg aaatgttgaa tcagggatca gacctggatg cagaagaagt
    15721 agcagaagtc ttgaaaccaa cttcagctta tgcgactccc ttaatggacg tccgtgcttg
    15781 gattgttgag gatgagaaga tttgtctggt taggggacaa ggagagggta gttgggcttt
    15841 gccaggtggc tttggtgaag tcggctattc tccaactgaa aatattctca aggaaattga
    15901 agaagaaacc ggttttaaag ccaaagttga aagactgcta gctgtttttg atatcaatcg
    15961 tttccaacta cagagcaaac aatatgcaaa gtttgttttt gaatgtaagc ttctcgatgg
    16021 acaattccaa gaaaatcaag aaattgcaga ccttcaattt tttgccattg atcaactgcc
    16081 agtcttatct gaaaaacgca ttaccaagga gcaaatagag attctttggc aggtttatca
    16141 aggtcagagg gagcaatatc ttgactaaga agatgattat cgtattttta aatccatttt
    16201 taacaactag catggtataa taatatgcag gaaaattttg aattatgagg aagactagat
    16261 gaatttatgg gatattttct ttacgactca ggcaaccaag ccgcccaaat ttgacctttt
    16321 ttggtatgtt agcctattta cgctcttagc cttaaccttt tatacagccc atcgctatcg
    16381 tgaaaagaag gtttaccaac gatttttcca aatcttgcag actgttcagt taatccttct
    16441 ttatggttgg tactgggtca atcatatgcc actgtcagaa agcctaccct tttaccattg
    16501 ccgtatggct atgtttgtgg tactcttgct tcctggtcaa tccaaatata aacaatactt
    16561 tgcattattg ggaacatttg ggacattagc agcctttgtt tatccagtgc cagatgctta
    16621 cccttttcca catatcacca ttctatcctt tatctttggt catttagcac tcttggggaa
    16681 ctctctagtt tatctattga gacagtataa tgcgcgattg ctggatgtga agggaatttt
    16741 tctcatgacc tttgccctaa atgccttgat ttttgtggtc aatttggtga caggtggcga
    16801 ttacggattt ttgacaaaac cgccattggt tggggatcac ggtctagtag ctaattattt
    16861 acttgtttca attgtgctgg tagctactat cagtttgact aagaaaatct tagaattctt
    16921 tttagctcaa gaagcagaaa aaatgattgt aaaggaagct taacacagag ctttcttttt
    16981 tgctcttaga gagtttttac aatcagctta taaaataaga atttctgaat agacaaactc
    17041 aaaaaatggc tgggaaattt aggaaaaaag caagcacgat taaatttttt gtgttataat
    17101 attttgtgaa tagctatgcc tatgtttagc tatggaataa tacgaagtgc gaaacttgga
    17161 agatagagag gaagcgatgt aatggctaga gaaggctttt ttacaggtct agatattgga
    17221 acaagctctg tcaaggtgct tgtggccgag cagagaaatg gtgaattaaa tgtaattggc
    17281 gtgagtaatg ccaaaagtaa aggtgtaaag gatggaatta ttgttgatat tgatgcagca
    17341 gcaactgcta tcaagtcagc catttcccaa gcggaagaaa aggcaggcat ttcgattaaa
    17401 tcagtaaatg tcggcttgcc tggtaatctt ttgcaggtag aaccaactca ggggatgatt
    17461 ccagtaacat ctgatactaa ggaaattacg gatcaagatg ttgaaaatgt tgtcaaatca
    17521 gctttgacaa agagtatgac acctgaccgt gaagtcatta cctttattcc tgaagaattt
    17581 attgtggatg gtttccaagg gattcgtgac ccacgtggca tgatgggggt tcgccttgaa
    17641 atgcgtggtt tgctttatac aggacctcgt actatcttgc acaatttgcg taagacggtt
    17701 gagcgtgcag gtgttcaggt tgaaaatgtt atcatttcac cactagcaat ggttcagtct
    17761 gttttgaacg aaggggaacg tgaatttggt gctacagtga ttgatatggg ggcaggtcaa
    17821 acgactgtcg ctacaatccg taatcaagaa ctccagttca cacatattct ccaagaaggt
    17881 ggagattatg taactaaaga tatctccaag gttttgaaaa cctctcgcaa attagcggaa
    17941 ggcttgaaac tgaattacgg ggaagcctat ccgcctcttg caagcaaaga aaccttccaa
    18001 gtagaggtta ttggagaagt agaagcagtc gaagtgacgg aagcctactt gtcagaaatt
    18061 atttctgcac gaatcaagca catccttgaa caaatcaagc aagaattaga tagaaggcgt
    18121 ctattggacc tccctggtgg tattgtctta atcggtggga atgccatttt accaggtatg
    18181 gttgagcttg ctcaggaagt ctttggcgtc cgtgtcaagc tttatgttcc aaatcaagtt
    18241 ggtatccgta atccagcctt tgcgcatgtg attagtttat cagaatttgc gggtcaatta
    18301 acagaagtta atcttttggc tcagggagcg ataaaaggtg agaatgactt aagtcatcag
    18361 ccaattagtt ttggtgggat gctgcaaaaa acagctcagt ttgtacaatc aacgcctgtt
    18421 caaccagctc ctgctccaga agtagagccg gtggcgccta cagaaccaat ggcggatttc
    18481 caacaagctt cacaaaataa accgaaatta gcagatcgtt tccgtggctt gatcggaagc
    18541 atgtttgacg aataaagagg aaaaataaat tatgacattt tcatttgata cagctgctgc
    18601 tcaaggggca gtgattaaag taattggtgt cggtggaggt ggtggcaatg ccatcaaccg
    18661 tatggtcgac gaaggtgtta caggcgtaga atttatcgca gcaaacacag atgtacaagc
    18721 attgagtagt acaaaagctg agactgttat tcagttggga cctaaattga ctcgtggttt
    18781 gggtgcagga ggtcaacctg aggttggtcg taaagccgct gaagaaagcg aagaaacact
    18841 gacggaagct attagtggtg ccgatatggt cttcatcact gctggtatgg gaggaggctc
    18901 tggaactgga gctgctcctg ttattgctcg tattgccaaa gatttaggtg cgcttacagt
    18961 tggtgttgta acacgtccct ttggttttga aggaagtaag cgtggacaat ttgctgtaga
    19021 aggaatcaat caacttcgtg agcatgtaga cactctattg attatctcaa acaacaattt
    19081 gcttgaaatt gttgataaga aaacaccgct tttggaggct cttagcgaag cggataacgt
    19141 tcttcgtcaa ggtgttcaag ggattaccga tttgattacc aatccaggat tgattaacct
    19201 tgactttgcc gatgtgaaaa cggtaatggc aaacaaaggg aatgctctta tgggtattgg
    19261 tatcggtagt ggagaagaac gtgtggtaga agcggcacgt aaggcaatct attcaccact
    19321 tcttgaaaca actattgacg gtgctgagga tgttatcgtc aacgttactg gtggtcttga
    19381 cttaaccttg attgaggcag aagaggcttc acaaattgtg aaccaggcag caggtcaagg
    19441 agtgaacatc tggctcggta cttcaattga tgaaagtatg cgtgatgaaa ttcgtgtaac
    19501 agttgttgca acgggtgttc gtcaagaccg cgtagaaaag gttgtggctc cacaagctag
    19561 atctgctact aactaccgtg agacagtgaa accagctcat tcacatggct ttgatcgtca
    19621 ttttgatatg gcagaaacag ctgaattgcc aaaacaaaat ccacgtcgtt tggaaccaac
    19681 tcaggcatct gcttttggtg attgggatct tcgccgtgaa tcgattgttc gtacaacaga
    19741 ttcagtcgtt tctccagtcg agcgctttga agccccaatt tcacaagatg aagatgaatt
    19801 ggatacacct ccatttttca aaaatcgtta agtaaatgaa tgtaaaagaa aatacagaac
    19861 ttgtttttcg agaagttgca gaggctagtc tgagtgctca tcgagagagt ggttcggtct
    19921 ctgtcattgc agttaccaag tatgtagatg taccgacagc ggaagccttg cttccgctag
    19981 gtgttcatca tatcggtgaa aatcgtgtag ataagtttct ggaaaaatat gaagctttaa
    20041 aagatcgaga tgtgacttgg catttgattg gtaccttgca aagacgtaag gtgaaagatg
    20101 tcattcaata cgttgattat ttccatgcat tggactcagt aaagctagca ggggaaattc
    20161 aaaaaagaag tgaccgagtc atcaagtgtt tccttcaagt aaatatttct aaagaagaaa
    20221 gcaaacacgg tttttcgaga gaggaactgc tggaaatctt gccagagtta gccagactag
    20281 ataagattga atatattggt ttaatgacga tggcaccttt tgaggctagc agtgagcagt
    20341 tgaaagagat tttcaaggcg gcccaagatt tacaaagaga aattcaagag aaacaaattc
    20401 caaatatgcc tatgaccgag ttaagtatgg gaatgagtcg tgattataaa gaagcgattc
    20461 aattcggttc cacttttgtt cgtataggta catcattttt taagtaggag agaaccatgt
    20521 ctttaaaaga tagattcgat agatttatag attattttac ggaggatgag gattcaagtc
    20581 tcccttatga aaaaagagat gagcctgtgt ttacttcagt aaattcttca caggaaccgg
    20641 ctctcccaat gaatcaacct tcacagtcgg ctggtacaaa agagaacaat atcaccagac
    20701 ttcatgcaag acaacaggaa ttggcaaatc agagtcagcg tgcaacggat aaggtcatta
    20761 tagatgttcg ttatcctaga aaatatgagg atgcaacaga aattgttgat ttattggcag
    20821 gaaacgaaag tatcttgatt gactttcagt atatgacaga ggtgcaggct cgtcgttgtt
    20881 tggactattt ggatggagct tgtcatgttt tagctggaaa tttgaaaaag gtagcttcta
    20941 ccatgtattt gttgacacca gtgaacgtta ttgtaaatgt tgaagatatc cgtttaccag
    21001 atgaagatca acagggtgag ttcggttttg atatgaagcg aaatagagta cgataatgat
    21061 ttttttaatt cgtatgattt ataatgcagt ggatatttac tccctgattt tggtagcctt
    21121 cgctgtcatg tcttggtttc caggtgccta cgaatccagt ttaggtcgtt ggattgtagc
    21181 gttggtgaaa ccagtgcttg ctcccttgca acgcctgcct ttacagatag cgggtcttga
    21241 tttatctgtt tgggttgcga ttgttttggt tcgattttta ggagaaaacc tagtgcgttt
    21301 tctggcgatg ataggatgaa taaagggatt tatcagcatt tctccataga agatcgtcca
    21361 tttcttgaca agggaatgga atggataaag aaggtagaag atagctatgc tcctttttta
    21421 actcctttta tcaatcctca tcaggagaag ctattaaaga ttttggccaa aacctatggt
    21481 cttgcttgta gcagtagtgg ggaattcgtc tcgagtgagt atgttcgagt tttattatac
    21541 ccagattatt tccaaccaga gttttcagat tttgaaatat ctctccagga aattgtgtat
    21601 tccaataaat ttgaacattt aacgcatgct aagattttag ggacagtcat caatcaatta
    21661 gggattgaac ggaaactttt tggagatatc ctagtagatg aagaacgggc gcagattatg
    21721 attaatcagc agtttcttct tctctttcaa gatggactaa agaaaattgg tcgtatacct
    21781 gtttcgctgg aggaacgtcc tttcaccgag aaaatagata agctagaaca gtatcgagaa
    21841 ctggatttat ctgtgtctag ttttcgatta gatgttcttt tatcaaatgt tttgaaacta
    21901 tctaggaatc aagcaaacca gttgattgaa aagaaacttg tccaagtaaa ttatcatgtg
    21961 gtagacaaat cagattacac tgttcaagtt ggagacttga ttagtgtgag aaaatttggt
    22021 cgcttgagat tacttcaaga taagggacaa acgaaaaaag agaagaaaaa aataaccgtc
    22081 cagttattat taagtaagtg aggaatagaa tgccaattac atcattagaa ataaaggaca
    22141 agacttttgg aactcgattc agaggttttg atccagaaga agtcgatgaa tttttagata
    22201 ttgtggttcg tgattacgaa gatcttgtgc gtgcgaatca tgataaaaat ttgcgtatta
    22261 agagtttaga agagcgtttg tcttactttg atgaaataaa agattcattg agccagtctg
    22321 tattgattgc tcaggataca gctgagagag tgaaacaggc ggcgcatgaa cgttcaaaca
    22381 atatcattca tcaagcagag caagatgcgc aacgcttgtt ggaagaagct aaatataagg
    22441 caaacgagat tcttcgtcaa gcaactgata atgctaagaa agtcgctgtt gaaacagaag
    22501 aattgaagaa caagagccgt gtcttccacc aacgtctcaa atctacaatt gagagtcagt
    22561 tggctattgt tgaatcttca gattgggaag atattctccg tccaacagct acttatcttc
    22621 aaaccagtga tgaagccttt aaagaagtgg ttagcgaagt acttggagaa ccgattccag
    22681 ctccaattga agaagaacca attgatatga cacgtcagtt ctctcaagca gaaatggcag
    22741 aattacaagc tcgtattgag gtagccgata aagaattgtc tgaatttgaa gctcagatta
    22801 aacaggaagt ggaagctcca actcctgtag tgagtcctca agttgaagaa gagcctctgc
    22861 tcatccagtt ggcccaatgt atgaagaacc agaagtagct ccaatgcatc cgataggtcc
    22921 aacaccagct acagaaactg ttgattcaat accgggattt gaagcaccgc aagaatctgt
    22981 tacaatttta taagaaatat tctgagaaca atatcttatc cttatatttc cagcgagcag
    23041 gagatggtgt gagtcctgta atccctattg ataagattat cctctcaaaa actcaagtct
    23101 gaagctagta agatttgacg tttcccacgt tacgggataa gagggagaaa gactaaatct
    23161 ttttccgaat aaaggtggta ccacgatttt cgtccttttt ggaagtcgtg gtttttaatt
    23221 tgttattatt tataaaggag ataccatgaa actcaaagac acccttaatc ttgggaaaac
    23281 tgaattccca atgcgtgcag gccttcctac caaagagcca gtttggcaaa aggaatggga
    23341 agatgcaaaa ctttatcaac gtcgtcaaga attgaaccaa ggaaaacctc atttcacctt
    23401 gcatgatggc cctccatacg ctaacggaaa tatccacgtt ggacatgcta tgaacaagat
    23461 ttcaaaagat atcattgttc gttctaagtc tatgtcagga ttttacgcac catttattcc
    23521 tggttgggat actcatggtc tgccaatcga gcaagtcttg tcaaaacaag gtgtcaaacg
    23581 taaagaaatg gacttggttg agtacttgaa actttgccgt gagtacgctc tttctcaagt
    23641 agataaacaa cgtgaagatt ttaaacgttt gggtgtttct ggtgactggg aaaatccata
    23701 tgtgaccttg actcctgact atgaagcagc tcaaattcgt gtatttggtg agatggctaa
    23761 taagggttat atctaccgtg gtgctaagcc agtttactgg tcatggtcat ctgagtcagc
    23821 acttgctgaa gcagagattg aataccatga cttggtttca acttcccttt actatgccaa
    23881 caaggtaaaa gatggcaaag gagttctaga tacagatact tatatcgttg tctggacaac
    23941 gactccattt accatcacag cttctcgtgg tttgacggtt ggtgcagata ttgattacgt
    24001 tttggttcaa cctgctggtg aagctcgtaa gtttgtcgtt gctgctgaat tattgactag
    24061 cttgtctgag aaatttggct gggctgatgt tcaagttttg gaaacttacc gtggccaaga
    24121 actcaaccac atcgtaacag aacacccatg ggatacagct gtagaagagt tggtaattct
    24181 tggtgaccac gttacgactg actctggtac aggtattgtc catacagccc ctggttttgg
    24241 tgaggacgat tacaatgttg gtattgctaa taatcttgaa gtcgcagtga ctgttgatga
    24301 acgtggtatc atgatgaaga atgctggtcc tgaatttgaa ggtcaattct atgaaaaggt
    24361 agttccaact gttattgaaa aacttggtaa cctccttctt gcccaagaag aaatctctca
    24421 ctcatatcca tttgactggc gtactaagaa accaatcatc tggcgtgcag ttccacaatg
    24481 gtttgcctca gtttctaaat tccgtcaaga aatcttggac gaaattgaaa aagtgaaatt
    24541 ccactcagaa tggggtaaag tccgtcttta caatatgatc cgtgaccgtg gtgactgggt
    24601 tatctctcgt caacgtgctt ggggtgttcc acttcctatc ttctacgctg aagatggtac
    24661 agctatcatg gtagctgaaa ctattgaaca cgtagctcaa ctttttgaag aatatggttc
    24721 aagcatttgg tgggaacgtg atgccaaaga cctcttgcca gaaggattta ctcatccagg
    24781 ttcaccaaac ggcgagttca aaaaagaaac tgatatcatg gacgtttggt ttgactcagg
    24841 ttcatcatgg aatggagtgg tggtaaaccg tcctgaattg acttacccag ccgaccttta
    24901 cctagaaggt tctgaccaat accgtggttg gtttaactca tcacttatca catctgttgc
    24961 caaccatggc gtagcacctt acaaacaaat cttgtcacaa ggttttgccc ttgatggtaa
    25021 aggtgagaag atgtctaaat ctcttggaaa tactattgct ccaagcgatg ttgaaaaaca
    25081 attcggtgct gaaatcttgc gtctctgggt aacaagtgtt gactcaagca atgacgtgcg
    25141 tatctctatg gatatcttga gccaagtttc tgaaacttac cgtaagattc gtaacactct
    25201 tcgtttcttg attgccaata catctgactt taacccagct caagatacag tcgcttacga
    25261 tgagcttcgt tcagttgata agtacatgac gattcgcttt aaccagcttg tcaagaccat
    25321 tcgtgatgcc tatgcagact ttgaattctt gacgatctac aaggccttgg tgaactttat
    25381 caacgttgac ttgtcagcct tctaccttga ttttgccaaa gatgttgttt acattgaagg
    25441 tgccaaatca ctggaacgcc gtcaaatgca gactgtcttc tatgacattc ttgtcaaaat
    25501 caccaaactc ttgacaccaa tccttcctca cactgcggaa gaaatctggt catatcttga
    25561 gtttgaaaca gaagacttcg tccaattgtc agaattacca gaagttcaaa cttttgctaa
    25621 ccaagaagaa atcttggata catgggcagc cttcatggac tttcgtggac aagcacaaaa
    25681 agccttggaa gaagctcgta atgcaaaagt tatcggtaaa tcacttgaag cacacttgac
    25741 agtttatcca aatgaagttg tgaaaactct actcgaagca gtaaacagca atgtagcaca
    25801 acttttgatc gtgtctgagt tgaccatcgc agaaggacca gctccggaag ctgcccttag
    25861 cttcgaagat gtagccttca cagttgaacg tgctactggt gaagtatgtg accgttgccg
    25921 tcgtatcgac ccaacaacag cagaacgcag ctaccaggca gttatctgtg accactgtgc
    25981 aagcatcgta gaagaaaact ttgcggaagc agtcgcagaa ggatttgaag agaaataaga
    26041 ttgaaaagtc taggcaaaat tcaatttgag aagaaaagac aactaatttt atagtctatt
    26101 aaacgcattg tatcacgttt ttgaatacct gatatgatgc gttttttatt tattttaaaa
    26161 atttgcgagg tatgactttt tatactcaac aagaatcaaa gagaaactta gcaagctaac
    26221 agtagtaaga taaaatagga atttgatatt agggataaga ttggtaaata gtgtaatatt
    26281 tttacaacaa taaatttata tagt
//
LOCUS       DBERDS010000025        25926 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.025, whole genome shotgun sequence.
ACCESSION   DBERDS010000025 DBERDS010000000
VERSION     DBERDS010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.025"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(1..644)
                     /locus_tag="ACL73E_001227"
                     /pseudo
     CDS             complement(1..644)
                     /locus_tag="ACL73E_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(1025..1885)
                     /locus_tag="ACL73E_001228"
     CDS             complement(1025..1885)
                     /locus_tag="ACL73E_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGS0801199.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1901..3178)
                     /gene="spxR"
                     /locus_tag="ACL73E_001229"
     CDS             complement(1901..3178)
                     /gene="spxR"
                     /locus_tag="ACL73E_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGS0801200.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(3171..3722)
                     /locus_tag="ACL73E_001230"
     CDS             complement(3171..3722)
                     /locus_tag="ACL73E_001230"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801201.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3738..4997)
                     /locus_tag="ACL73E_001231"
     CDS             complement(3738..4997)
                     /locus_tag="ACL73E_001231"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGS0801202.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGVSIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGTSVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(6152..6310)
                     /locus_tag="ACL73E_001232"
     CDS             complement(6152..6310)
                     /locus_tag="ACL73E_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801203.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(6320..7630)
                     /gene="obgE"
                     /locus_tag="ACL73E_001233"
     CDS             complement(6320..7630)
                     /gene="obgE"
                     /locus_tag="ACL73E_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGS0801204.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(7694..7828)
                     /locus_tag="ACL73E_001234"
     CDS             complement(7694..7828)
                     /locus_tag="ACL73E_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGS0801205.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7887..8063)
                     /locus_tag="ACL73E_001235"
     CDS             complement(7887..8063)
                     /locus_tag="ACL73E_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS0801206.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(8094..9419)
                     /locus_tag="ACL73E_001236"
     CDS             complement(8094..9419)
                     /locus_tag="ACL73E_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0801207.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRSSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(9435..10478)
                     /gene="cpoA"
                     /locus_tag="ACL73E_001237"
     CDS             complement(9435..10478)
                     /gene="cpoA"
                     /locus_tag="ACL73E_001237"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGS0801208.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(10593..10922)
                     /locus_tag="ACL73E_001238"
     CDS             complement(10593..10922)
                     /locus_tag="ACL73E_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS0801209.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10936..12045)
                     /gene="rpoD"
                     /locus_tag="ACL73E_001239"
     CDS             complement(10936..12045)
                     /gene="rpoD"
                     /locus_tag="ACL73E_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGS0801210.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(12048..13808)
                     /gene="dnaG"
                     /locus_tag="ACL73E_001240"
     CDS             complement(12048..13808)
                     /gene="dnaG"
                     /locus_tag="ACL73E_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGS0801211.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13898..14656)
                     /locus_tag="ACL73E_001241"
     CDS             complement(13898..14656)
                     /locus_tag="ACL73E_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801212.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(14653..15519)
                     /locus_tag="ACL73E_001242"
     CDS             complement(14653..15519)
                     /locus_tag="ACL73E_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801213.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMDLMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(15588..16592)
                     /gene="trpX"
                     /locus_tag="ACL73E_001243"
     CDS             complement(15588..16592)
                     /gene="trpX"
                     /locus_tag="ACL73E_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0801214.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(16705..16922)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(17005..19701)
                     /gene="ppc"
                     /locus_tag="ACL73E_001244"
     CDS             complement(17005..19701)
                     /gene="ppc"
                     /locus_tag="ACL73E_001244"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGS0801215.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWHNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFDSSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19721..20950)
                     /locus_tag="ACL73E_001245"
     CDS             complement(19721..20950)
                     /locus_tag="ACL73E_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS0801216.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(21106..21408)
                     /locus_tag="ACL73E_001246"
                     /pseudo
     CDS             complement(21106..21408)
                     /locus_tag="ACL73E_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21856..22077)
                     /locus_tag="ACL73E_001247"
     CDS             complement(21856..22077)
                     /locus_tag="ACL73E_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0801217.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(22757..23968)
                     /locus_tag="ACL73E_001248"
                     /pseudo
     CDS             complement(22757..23968)
                     /locus_tag="ACL73E_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428251.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(23970..25214)
                     /locus_tag="ACL73E_001249"
     CDS             complement(23970..25214)
                     /locus_tag="ACL73E_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit family protein"
                     /protein_id="HGS0801218.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQGLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMLVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            complement(25238..>25926)
                     /gene="galE"
                     /locus_tag="ACL73E_001250"
     CDS             complement(25238..>25926)
                     /gene="galE"
                     /locus_tag="ACL73E_001250"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGS0801219.1"
                     /translation="KKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYI
                     EVLLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPY
                     LNIFGVDYSTPDGTCIRDYVHVNDLVYGHRKALEYIFNTDEGLYEVINLGSGVGFSVF
                     EILHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKW
                     QQKHPNGYDD"
BASE COUNT         7923 a         5632 c         4281 g         8090 t
ORIGIN      
        1 aggctttatc ttcagctgtt agcggcttga gtttgctgga tttacgtgga gtttgtgctt
       61 gaggatatat cttcatgagc ccttgataac cactgtcggc caagatttta ccagcttgtc
      121 cgatatttct gcaactcatt ttgaacaact tcatatcatg actatagttc acagcgatat
      181 ccaaagaaac aattctccct tgacttgtga caatcgcttg agccttcata gcgtgaaatt
      241 tctttttacc agaatgattc gctaattctt tttttagggc gattgatttg tacttccgtc
      301 gcatcaatca ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgt aacaccactt
      361 tgaacaagag ttacttcaac ccattggctc cgacggatta agttgctttc gtgaatacca
      421 aaatcagccg caatttgttc ataagttcga tattctcgca catattgaag agtggccata
      481 agaaggtctt ctaggcttaa tttaggtttt cgtccacctt ttgcgtgttt aagttgataa
      541 gctgttttta atacagctaa tatctcttca aaagtcgtgc gctgaacacc aacaagacgc
      601 ttaaatcgtg catcagttag ttgtttactt gcttcatcat tcatagaact actataccat
      661 attttatttc gcaggaagtc taatctaaaa aaggtaaatt taagattggc aatacgaacg
      721 ttaaacagaa ttccatttct ctttttagaa tcaaaacgac aatattgtgg aatctctaca
      781 agaacaatag actgcgacac taaaatatcc tctcttagtt ttactttact aatagtatat
      841 aggaggagag ccctgaatcc tagacccttt gttatgatgc gcttacaaac agagttggaa
      901 aaaatcttaa aagcagaaaa acgcatgata tcagccccta acacttgata caatgcgttt
      961 tattatgaaa agatctactg gattttttat caaaataaac ttccagtagt cttttcactt
     1021 tttattaata agttccttct tcaccttggc tagtcaagat aacaggtcca tctttcgtaa
     1081 tgacaaattg gtgttcatac tgacatgaca atccaccgtc aatggtctta tgcgcccaac
     1141 cagttttcat atctgtatca atttcccaat cgcctgtatt gatcattggt tcaatggtta
     1201 agaccattcc ttcacgaaga cggagtccac gacctgcaat accatagtta ggaaccattg
     1261 gttcttcgtg catagttggg ccaacaccat gaccaaccaa atcacgcact acaccgtaac
     1321 cacgactttc agcgtattct tgaatagccg caccgatatc accgatacga tttccaacaa
     1381 cagcttgctc aatacccttg tacatagctt ctttggttac atccatcaag tttttgactt
     1441 cttcggacgg tgtaccaaca gcataagccc aacatgagtc tgctaaacca ccagaatagc
     1501 tctgagtgta ttttttcatt tgttcaacat tgttgaagtt taattttgag acatttaggt
     1561 cagatttagc aatgggacct cccaaaacca tatcaacttt gagcaaatca ccatctttca
     1621 agatataatg acgagggaaa gcgtgagcca cttcatcgtt aagagagcaa caggtagcat
     1681 aaggatagtc catcatggca ccgtcaaccc caatctgaag tggaaggaaa ttttcttctt
     1741 tacaacgacg gcggacatat tcttcaactt cccacatatc tacgcctggc ttaatcaaat
     1801 cacgtaagcc tatatgaata cttgctagaa aatcaccagc cttgtccata gcttcgattt
     1861 cacgagctga ttttaatgtt atcatctttt ctcctagttt ctaattaatt ttaacagtca
     1921 catttgcttt tgaaacaatc tggtgaccat gataaatatc gtaatcaatt atagctgacc
     1981 gtctcgtatg atgaataatc cgtgcctgaa tgcgcaatat atcatctatc tgaacagcct
     2041 gcaaaaagta gatcagcatc tgctcgataa tgagattgcg accactatta acaactaaat
     2101 cttgggtcat gtgggtcaga atttctgcca atacaccatt agccaaaact ccattttttt
     2161 ctagcataaa gggttccact gtaatgacta cttcatcatg gtgataagag agcttttgtc
     2221 caatctgctc agaaaaagtt ggtagagccg aaacttggga acggctcatc ttctccatga
     2281 catctcgtcg cgtcacaacg ccaagcaaag tttgattgct tcgaacaact ggtaccattt
     2341 caaagtcttc tgcgatcatc cgttgactca cattggcaat atttgtcgat aatccaacca
     2401 aaaatagact acgagacata accttatcaa ttgtcgtgct tggtgattta tcaccagcgt
     2461 ctctcatggt tacaacacca acaacgacct gatgttgatt gataacaggg aaacggctgc
     2521 tacgattctt acgaaccaag tccaaataat ctttaactgt atctgtctct cttagaaaac
     2581 catactcatg actagggcga taaagtttct caactgtcag aatatcagtc ttgatttgga
     2641 catttgacaa ggctttattg atcatggtcg cgacggtaaa ggtatcatgc ttacttctta
     2701 gaacaggaat ccctttttga ttggccagtt taagcacatc atcatgaacc tgaaatcccc
     2761 ctgtaaccag aactgcattt tcattttcca aggctagcaa ctgaatacgg gttcggtctc
     2821 cgacaatcaa gagcccccca tcatgaaggt aagacaagat attttgttca gtcatggcac
     2881 caattgaaaa cttactaaac tctctctcta aaccttcttg cccagccaga acctcagaag
     2941 aagtcacttc tgcaatttca gcaaacgtta atctctctat agcaactttc tgggatttaa
     3001 cacgaattgt tccacttcta ggacgggtct ccacaattcc acggttttca gcttctttaa
     3061 tagcccgata ggctgttcca tcactaactc ctagatgatt cgaaatgcta cgaacactga
     3121 cccttttacc tactggtaat tcctccaaat agcttagaat ttcctgatgc ttactcattg
     3181 aactctcctt ttacataccg aaattcaaga taatcccgca tttttcttgt gtaacgatca
     3241 cttcccttaa actgacggaa caaactaaat ccagacttaa gagcaactct ttggctagct
     3301 ttattttcaa ggtgggtaat gataaataat tgttttaagc caaattcctc aaaagaaagc
     3361 tgacaaattt ttctaacaac ctctgtcata aatccttgcg accaagcatc ttttctcaaa
     3421 aaatagccaa gctcagcttc ttttttgatt tcatctaact tctcaaattt aatagaacca
     3481 atcatttgtt gatttttctg gtcacaaatt gcccacactc ccaaagggga cttcataaag
     3541 taattggcca gtgcatattg actttcttcc agacttgcct gcgttgggaa aataaattga
     3601 agattttctg gatttgaagc tatctcgcgg aagtcctgac tatcactaaa aaagaaagga
     3661 cgcaaataca agcgatccgt ttcaaaaaaa gaaaacattg ctaatttggt ccaaatattc
     3721 ataaacacct ctacggttta atcctcaaca agtctaatat ccgctcctaa attacgtaat
     3781 ttttcgataa tatcagaata accacgtaag ataaactcga tattggtaat ttcagtttta
     3841 ccttcagcca taagcccagc aatgactagt gcagccccag ctcttaagtc ggtcgcttta
     3901 acactggtcc cacgtaaatc acgtccaccc gtgtacaaaa tatgaccatt tgttgtcgaa
     3961 atatccgcat ccatctttgc tagttcaaaa acatgattta cacgtttttc gtaaatcgta
     4021 tcgacaattg taccacgacc attcgctctt agtaaaagag gggtaagcgg ttgttgcaaa
     4081 tcagttgcaa agcctgggta aggagctgtc ttaatattga ttgctttcaa attagactgt
     4141 tcctcgacaa aaatgctgtc ttcagataca gtcattctca ctcccatttc ttccaactta
     4201 gcaataaacc cttccaggtg ttcgtaaaga acattattta tacgaattcc tttaccaact
     4261 gcagcagcta aagatatata tgttccagct tcaatgcggt ctggaatcac ctgatgacgt
     4321 gtcccatgta atctttcaac accatcaata atgatgatat tagttcctgc cccacggata
     4381 tgggcaccca tattattcaa gagagtagct acatcaataa tctcaggttc acgagctgca
     4441 ttttcaataa tagtacgacc atttgcttta accgcagcaa tcatcgtatt aatcgttgct
     4501 cccacactaa ccgtatccat gtaaatactt acaccatgaa gtcctgtatc tttagcagat
     4561 aacttcatgt tatctccctc gtagctagca gtggcaccca tagcttcaaa cgccttaagg
     4621 tgtaagtcaa tcggacgagg accaagatca catcctcccg gtagaccaac tgtcgcttca
     4681 ccaaaacggc ctaagaggct cccataaaaa tagtaagatg cacgaagact gttaatttta
     4741 ccataaggca ttggaatatt ttgaacacct cttggatcaa tctccaagac atcgtcataa
     4801 cgcttaacag tagctcccat caattccatg atttcgacaa gactggctac atccgaaata
     4861 tctggaacac aatccaaagt caccacatca tcagccaata taatagctgg aattaaggcc
     4921 acaacactat ttttagcacc actaatagta atttcacctt gcagtggtaa tccaccattg
     4981 ataacaattt ttctcattct aagttttcaa tactctttca agatttctaa taaggtcttc
     5041 aaaataaagt atatcataaa tttatccttt tttccatcct tttcaatttt attggctaaa
     5101 tcagagttga cgagttagta actgaattac taatactcaa taaaaatcaa agatcaaact
     5161 aggaaactag ccgcaggttg ctcaaaacac tgttttgaga ttgtagatgg aactgacgta
     5221 gtcagtatcc tacacatacg gcaaggcgat attgacgtga tttgaagaga ttttcgaaga
     5281 gtataatctt tctcgaatcg ctattgcccc ttttttatcc cctaaaactg agtaggagct
     5341 aagactagat ctcttatcta agtatcggaa tacggctgtt caactaaatt ttagcaagaa
     5401 cttctccccc ttctctcagt tcacagaagc gttttataca taccgtccta tcagacaatc
     5461 tattttaaag ataaccgtga ctcaggatca cttctatctg tcgttttctc tttatagtga
     5521 tagacctcac gggataagtc gtacatcttt cctcgtgtat acaagatatg agggcgttaa
     5581 aaggttacag tgaaaataga aaatcttagt acgaattcaa ttactctcgt gatttacgca
     5641 tataggttac gactaccttt ttggacttta gaatttgagg ccctcttatc cgctatatac
     5701 gccttattat cacgttcctg ttcgtagagc cacgatttcg ctatcccttc ttctgacaat
     5761 tcttatttcc agcgtcagac ttaaaacggt ctatccccag accattttaa tctgctacct
     5821 cacgatagtc aggcttggga atcgctattt gactcgccga gaactttgac atcagatata
     5881 ctataacaaa ttgaaataag aatcaaacaa tttaattttg aaattcaaat caatttataa
     5941 caatatagtt gattgaaact agaatagtac atctctgctt ctaaaacatt gttagaaatc
     6001 gattttactg tcctgatcga tttgtcctgt tctcatttca ttttactata ttttagaaga
     6061 tatgctgtgc tattccagat tcagtttgct atacatgcct gtcgtaccac aaaatcccgt
     6121 gtctgatgag gcacgggatt ttttagcttc tttactgaga tggattttcc tttttagttc
     6181 gtgccaatct caaggcacga tttggattga gacgattaaa tagttcttcc aatttctttt
     6241 cattccaaac gtctgcggcg gaaacaaaat taccatccgc atctcggaaa gatatcggtt
     6301 tatctcccat accagtctcc tagtctacaa attcaaactc aaatttacca atgcggacca
     6361 aatccccatc tttagctcca cgcgcacgaa gggcttcatc aacccccata ccacgaagct
     6421 gacgggcaaa tttcatgaca gattcatcac gatcaaagtt ggtcatatta aagagtttca
     6481 tgagtttttc accagaaagt acccatgtcg catcgtcatc acgactaatt tcaaaggctt
     6541 tttcttcttc gtcaaatcca tagtaagctt cttcttccat atcggactcg tcgtagagca
     6601 aaaattctgg tgtcttgtct aacaattcag ctgtagcatc taaaagtgtt gccagacctt
     6661 gcttggtcaa tccagaaatt gggaagatag ctggtaactc ttcaaattca tcataatttt
     6721 cagccaattt tttcttaaag tcttcaagat tttcctgact ctcaggcatg tccatcttat
     6781 tagctacaat aatctgtgga cgctccatga ggcgaagatt gtaagactcc agctctttat
     6841 tgatagctag gtagtcctca tatggatcac ggccttcgct agctgacata tcaatgatgt
     6901 gaaggataac acgtgtacgc tcgatgtgac ggaggaactg agttcccaaa ccaacacctt
     6961 gactagcccc ttcaatcaaa cctggcaagt cggctactgc aaaggattca cctgattggg
     7021 tgcgaaccat acctaaattt ggtacaatag tggtaaagtg gtaggcacca attttaggct
     7081 tagctgaggt aataacactt aaaagtgttg acttccctac agatgggaat cctactaaac
     7141 cgacatctgc caagattttt agttccaatt gtaactcacg ttcctgacct ggttctccat
     7201 tttcagagat ttccggtgca ggattttttg gtgtcgcgaa acgaatattt ccacgtccac
     7261 cacgaccacc gtgggcaacg ataaattctt gcccatgttc aatcaaatct gttaaaacct
     7321 tgccagtctc cgcatcacga acagtcgtac cttgtggtac tcgaactcta aggtcctcag
     7381 caccacgacc atgcatccct ttggtcatcc ctttttcacc agaatcagcc ttgaaatgac
     7441 gattgtagcg gaaatccatc aaggtacgta gtccttcgtc tacaacgaag accacattgc
     7501 ctccacgacc accatcacca ccccaagggc ctccattagg gacatatttt tcacgacgaa
     7561 aggcaaccat accatcgcca ccattaccag ccttgacctt aatcttagct gtatctaaaa
     7621 acatactcat tatttcttct cactttaaaa aagggctggg aaatcccagt cactaaattt
     7681 tcttgaatct attttataga ttactgaggg caccaattgc agttgcaaaa attcccaata
     7741 aacttgctac tagcatgata atcacgataa acaaggttat tttctcaaac atagtttttt
     7801 tacgatttcc attatctcca aatgccattt ttctctcctt cgttacattc tattttctat
     7861 tatcttagca tgaattgagc tagttttcaa tagtcagttg ctactggtgc gataatccat
     7921 aaaataatgt aagctacaat tccagctccg taacagcaag taagaacacc ccaaatgact
     7981 tgaacgatag tcggatccat atccagataa tgggccaccc cagcacaaac acccgcaatc
     8041 tttttatcac gaccgcttct cattaattgt ttttttcata gctgttcctc tttctattct
     8101 tcatggtctt tccaatagtc tctcatactg atcaactgtg tttttgaagc cttcaacatg
     8161 cgtctagatc cttttacagg tacagcaacc acctgttgct gaagatacaa aactgtctta
     8221 aagatacgct gactgaccgt atcatcttta gccaaatctt tctggaagtt atttgaaata
     8281 atggcatcca gataaaactc atgcactcgt ttcccaaagt tctcagctga aatctcatac
     8341 aatttctctg ataaggtatg ctcgttcatg tctggtgttg caatcagggc ttccaaaata
     8401 gcaccagcca aatcatgttc tccatagtac aaggttccaa acattttatc actgatgagg
     8461 ttgttcaaat aaggatttcc gtgagcaatg acaggtgttc cactggctaa gctttccaag
     8521 taggtcaaac cttgcgtttc gcttgtcgat gccgaaatga agaaatccgc cgctttatag
     8581 taaagagccg tctcactagg agcaatcatc cctgtaaaga tgactgagtc ttgaatctct
     8641 aggttctggg cttgctcttt gaggtcattc agataagggc catccccagc tactaccagt
     8701 ttaaccttgt cttcctcttt cagaacatca gcaaaggctg ctaaaactgc ttgaatattt
     8761 ttttcatagg agattctcga aagactaagc aacgtctttt caccatcttg aatccctagt
     8821 ttactacgca gttctttcaa attttcctgc ttgatttccg gacgctcaaa cttggctaat
     8881 tcaatcccag taggaatgac ccgtttttca accttgacct tataatcaga tagcaagtca
     8941 cggacaatct cactagggca aataacccca tccacatcat gcaggaaacc tctaaccaga
     9001 tacttgacca tactcgaccg gatcaacatc cccttagcaa tataatggac atagtcttca
     9061 tactgggtgt gataggtatg gatgactgga attttcaatt cacgcgcaat ccaaatcccc
     9121 aacaggccaa gagaaaattc tgtctgagta tggataatat ctagctgata ctgtttagca
     9181 atttcaagtg ccttgctaaa acctcggtag gcaaagcgac gatccttaaa agcaaagaaa
     9241 ggaacacttg gaatgcggat aatttgccaa tcttcgtagc gattgacatc cttatctgtc
     9301 gtcgtaaaga taaaaacagc atgtccctgc ttttcaagtt ctgttttcaa ggttcgaata
     9361 ctggtcgcaa caccagaaac ctgaggaaaa taggtatctg taaataaacc aattcgcata
     9421 gattacctca ctttttactt tctccctaaa gcggcttgtt tctcataaaa gtccaaccag
     9481 atttgtaaca gatgctcttc agaatactct ctggaaatat tcttggcctt ttctttgaga
     9541 tcttttaaga cagcaggatt tgcttgatat tccaaaatag cctctttcat ctcttctcta
     9601 cccgctgtcg cccgataatt tccctccaaa atcaccttat agagatctaa atcacgcaac
     9661 ataataggag cctcacaact cgcagcttct aaaatagtca taggaaagag ctcattgtaa
     9721 ctaggcaaca agaaaagatc cgctagagca tacaattcgc gcatccgctc tggcgataca
     9781 atgcctggaa aaatcaaatt tttaggggga ttttccataa ttttcttata gtgttcataa
     9841 ccatctgtca taccaccaaa agagaagcca ccagcccaga taaaggtaat ctgaggcaat
     9901 tcctcagcca gacggataaa gtcatcaatc cctttacgtt tctgaacttg cccagcacct
     9961 actacgataa actgattgtc actaagacca agatctgtgc gcagtctgac tacctcttct
    10021 tgtggtagag gatgccattt ttccttgttg acaaagttag gaatataggt cactttttca
    10081 cgtggaatac cagctgctac caaatcctca ataaacatag gattgaccac aaccaagtgc
    10141 tccatccggt tgtaaaaaga aaatacatag cgtttcacaa ttccctttaa gaaaaatgga
    10201 attttcaaac ttccttcaag tgtagctggc aagaaatgca catagccaat ctttctccct
    10261 gagcgtttct tttggaaggt tgataaataa tagggaaaat caatcgtatg aaagtgagtc
    10321 acatctgcct cgattggaag attttctgta acaatcaatt ggtccttggc agcacggtga
    10381 agaagacgaa ctaattcacg gtaagcacct gaaactccct gtcctgctac tttctcactt
    10441 gaactcaaca tattgatgcg taatttcttt ttctccataa ctactattat atcattttct
    10501 ttgaataaaa tcagcaaaag aaaggagaga ctagaggaaa agaggggaaa tttcctcgct
    10561 tttccaacag tctctcacat gcttttatat gtttacttaa tgcctagggc aatgcgggca
    10621 tagcgactca ttttttcaac tgtccaggct ggataccaga ctaatttaac ctcagtatcc
    10681 gttacttctg gaacctctat catagcatca taaatctggt ctgtcaaaag gtctgctaag
    10741 ggacaaccca tagttgtcaa agtcatgtca atctctgttt gccctgtgtc accgtcaaaa
    10801 cgaatctcat agatcaaacc aagattgaca atatcgattc ccaactcagg gtcgatgact
    10861 tcttccaagg ctgttaaaat ccgtgttttg atgttttcaa tttgctcttc tgtataagcc
    10921 atattttcct cactcttagt cttcaataaa atcacgaagc ggtttgctgc ggcttggttg
    10981 gcgtagtttt ctcaaagcct ttgcttcaat ctgacggata cgctcacgag ttacgttaaa
    11041 gactttcccc acatcttcaa gtgtgcgcat ttttccatca tctagtccaa aacgtagacg
    11101 cagaacattt tcttcacggt ctgtaagagt atctaagatt tcatccaatt gctcacgcaa
    11161 gacgatacga gtcgtataat ccactggatt ttcaattact tcatcttcga taaagtctcc
    11221 aaggtggcta tcgtcctctt caccgatagg agtttcaaga gatactggtt cttgggcaat
    11281 cttcaagatt tcacgaacct tatcaggtgt catatccatt cgttcagcaa tctgttctgg
    11341 tgtcggatct tgccccaatt cttgaaggag attccgctgt tcacgaacca atttattgat
    11401 agtttcaacc atgtgaactg ggatacggat ggtacgagct tgatccgcaa tagcacgagt
    11461 gatagcctga cgaatccacc aagttgcata agttgaaaac ttgaaccctt tagaatagtc
    11521 aaacttgtca accgccttca tcaagcccat atttccttct tgaatcaagt caaggaactg
    11581 catgccacga ccgacatagc gtttggcaat agaaacaacc aaacgaagat tggcttccgc
    11641 aagacgttgt ttggcttcga tatcgccagc ttcaacagcc agtgccaact ctttctcctc
    11701 ttcattggtc aagagaggaa cgacccctat ttctttcaag tacatacgga cagggtcatt
    11761 gaccttagca gaagttgacc caatcaagtc ctcatcgctg agttctggtt cttcttcatt
    11821 gctaagaaca cgcgcacttg gatttccttc gttatctgtg atagaaatgc ctgcatcctg
    11881 aatccgttgc aagagatctt caatcccatc agcgtccaag gtaaaaggaa taaccagact
    11941 tgcattgatt tcatcatctg ttgctgtccc tttttgctta tgattacgga taaattctgc
    12001 tacctgtacg tcaaatgttg ttacttcttt ttgttttgtt gccattatta ctccattctt
    12061 ctcttttggg aaattaaacg ttccaattct tctagggctg tatctgtatc tcctacatgg
    12121 ctagcttcct gcaccttctt tttgattctc atattgtcct gattcaagag agccttgttt
    12181 cgagtcatct ctacttcact aagttcctgc ggcgatatct cagcaggcaa atcctgagct
    12241 aaaacttggt accaagctct ttcaacttcc tctgtctgct ctgctaaaac ttctggagga
    12301 agatttccat actggccaag caagtcatat aagacctgaa attcaggtgt agcaaatgca
    12361 aagtcttctc gcaaacggta atcgttcaaa acaagagggg attccatcat ccgatagagt
    12421 agatgggctt ctgccctcat aatagccgat aactgcttgg tgataggcat ggtgattggc
    12481 gtcggtctgg aaattccttc catgcgattc tgcctttgca cctgacgact ctcattaaca
    12541 atctgctcaa tctgggtata atcaaaggac gccagactgt cagctaaaat atgaatatag
    12601 ctgttttgag cagcgatgga cttttcttga acaatcaagg gagctatttt ttcaataaac
    12661 tcaatctgag cctgcagatt ttcactgttt tcaggtttgt actgatgaat gtagaactca
    12721 atcggactaa tacgagtttt tgttaataga taggccaagt cttctggacc atttttttgt
    12781 agatactcat caggatccaa gttatcaggc atgctaacga tttgcacagg catatcacca
    12841 atttcatcca atgctttcaa tatcgcggct tgcccagcct tatctccatc gtaaacaaga
    12901 accaatttct tggttaacct tttcagatgc tcaacatgct ctcgactcaa ggccgttccc
    12961 atcgacgcca cagcattttc gattccagcc cgataggctg caataacatc catgaatcct
    13021 tccatcaggt aaatctcact agcttttcca gaagatcttt ttgccctatc catatgatat
    13081 aattcgtaac ttttgttaaa aattgcagtc gatcggctgt ttttatactt agaagtttgt
    13141 gaatccgttt tttgccagat acgacctgag aaggcaatga cctttccttg gtcatttgtc
    13201 aggggaaaca taatgcgatt gtgaaaggtg tctacaaatt gattggcatc cgagagataa
    13261 aacaggcctg aatccagtaa atcctcttca cgatactgat cagacaaacg ttgatagaga
    13321 tagtttcgtt ctggaggtgc taaaccaatc caaaaatgtt taagcacttc atctgtcaaa
    13381 ccccgctgat aaaggtaatt tctggcctct tctcccatag tcgttgtcat gagaatagca
    13441 tggtaaaatt tggctgcatc ttcgtgcata tcataaagag cttggtgagg cgaggctggc
    13501 ttctgttcac tataaagcgg tttttcaacc tcaatcccga cacgctgacc taagatttgg
    13561 acagcctcca taaaggtaac cccttggtac tcctcgatga atttaaagac atcacctgag
    13621 cgaccacaac caaaacagtg gtaaaactgc ttgtcctcta caacgttgaa agaaggtgtt
    13681 ttttcaccat gaaaaggaca gagccctaga tagttccgtc ctgccttttg taaagaaatc
    13741 acatctccta tgacttccac aatgttggca ttgtttttga tttcttcaat gacttgtttg
    13801 tcaaccatac acaatacctc catgttatca tagtttactt tatatagtat actttatttc
    13861 agaaaaaaag taaaccattt cactcatttt ccctacttta ttcaaagagt tgataataat
    13921 cagagatttt catttttgct ttttcttctt ggtttaaatc ttggataatc cgtccttctt
    13981 tcatgacaat caagcgattg ccgtatttga gagcatcttc catatgatga gtaatcataa
    14041 gggctgttag ctgatctttc ttaacaaatt catctgtcaa ttccatcaaa gcaacactag
    14101 tctttggatc cagggcagca gtatgctcat ctaacaggag taattcaggt cgcttcaagg
    14161 ttgccatcaa gagactcaaa gcctgtcttt gtccacctga taagaactca atcggtgtat
    14221 tcaagtgttt ctcaagacca tttcctactt tttcaatggt tgcctgaaat tcatccttat
    14281 agctagtcaa gcgtcttggt aacaatccac gcttttcacc acgaaacttg gcgattaaaa
    14341 gattttcagc gaccgtcata cggggagctg tccccatctt tggatcttgg aagacacgag
    14401 acaggtactt ggcacgcttc tcgggtgaaa acttagtgag atcttcacct aaaatacgga
    14461 tagttccact agttagtgat aaggtccctg ctatagtgtt aaagagagtt gattttccag
    14521 caccatttcc gcccaaaatc gtgataaagt cccgttcaaa aatttctaag gaaacatcat
    14581 ttaaaataat cttttcttca tcaaagccat ttttaacgat tttggttgca ttttttaatt
    14641 ctacaattgc tgtcatttgc ttaacttggc tcctttcaag attgtttgct taaatgttgg
    14701 aatcatgagg cagactgcta aaatcaaagc actgtataaa cgaaggtaac ttgtattaaa
    14761 gccaagtgcg ataactgccc acactaaaaa ttgataagcg atagaaccta caacgatagt
    14821 aaccaaacgc tctgccaagc tcaaactctt gaaaataact tctccaataa tcaaacttgc
    14881 aagccccaca acgataaccc cgatccctcg agacacatcg gcatagcctt cttgctgagc
    14941 aatgagggca cctgcaaggg caatcacacc atttgataag accaagccca tgagatccat
    15001 gcgtccagta tgaatcccga aacttctagc catatcagga ttatcccctg tagcaatata
    15061 ggcttgtccg agtttagtgt ccaagaaaaa gagcatgaga gcaataacaa tgctcacaaa
    15121 gatgagacct gtcaagagtt gattcaaatc cgaatcaaaa ggcaaaacat cctgaatttg
    15181 cttggttcca agcaggccta aatttgcacg tcccataatc aagagcatga ttgagtgaca
    15241 agaagtcatc accaaaatcc ctgagagcaa ggttgggatc ttcccttttg tataaagaag
    15301 gcctgctgcc attccagcca aacaacctgc tcctacagca acaagtgtcg ctaaaaatgg
    15361 attcacgcct ttggttatca aagtgacagc aacagctccc ccaagaggga aggaaccttc
    15421 tgtcgtcata tctggaaagt ttaaaatcct aaatgtcata aagattccca gacctagaat
    15481 agcccagaca aatccttgag aaataatgga aacaatcata ttttatttaa tcctttctat
    15541 attcatcttt ttaaaaaatg ggaagagtct cctcctccct accttattta ttcgatgact
    15601 tgtcctgctt ctttgagaac agactcagga atagtaatac ctagttcttg tgctattttt
    15661 ttattgataa ctgacttacc agttgaaaag acattgactg gggtatcggc tggttttgca
    15721 cctttcaaga cttgcacaat cattttacct gttgccacac caaggtcatg ttggtcaatt
    15781 acaactgatg ccaaaccacc tacttctacc atagctgtcg cactgggata aattggtttc
    15841 ttagaacttt gattgctaga gacaaccgtt ggaaatcctg atgcaatggt gttatcaatt
    15901 ggaacccaaa tagcatctac cttgctagtc ataacagtga cagttgaggc aatttcattt
    15961 gttgaaggaa ctgcaaatgt ttccactgtc agacctgctt tttcagcata agccttaaat
    16021 tcttcgacct gtgtttttga attgtcttcg ctacttgagt aaagagctcc gattgttttc
    16081 acattcggtg tcagagcctt gatgagttca acttgttgtt gagctggatt gtggtcagat
    16141 acccctgtaa cgttgccacc tggttttttc aaatctttaa ccaagttagc accaattggg
    16201 tctgtaatag cggccatgat aaccggtagg tcttttgttg cactagccaa cccttgggct
    16261 gctggtgttg cgataccaac cacaaggtca ttcccatttg caaccaattg tttactcatt
    16321 gtcgcaacct tactttggtc accttctgag ttcataaaat caattttaac ttgatcatct
    16381 ttatatcctt cttctgcaag tccatcttgg atccctttat aaatcaaatc aagggatgga
    16441 tggctcacaa attgaagcac accaatcttg gttattttct tctcatcctt attattctga
    16501 acttctgatt tattcattga agaataaatc aagcttcctg ctactaagac tgctaatgca
    16561 gcaataattc caattaaacg tttatttttc attctgtttc tcctttttat ttcctttaac
    16621 atatttcact tatctaaaca agcgacgcca ttgttttctt tccatactaa cctccatcaa
    16681 aaaaatcctc acacaaaaaa cttgtgtgag gacgtcgatg cgcggtacca cctcaattat
    16741 agggaatttc cctatcgctc agtctcgcaa taacgagatg cactgtaagg tgtgcttacc
    16801 gaatttttat aatttcaaat tctaaatagc attcagccca attttcatca ttgccactta
    16861 tctgttttca gctaccacag actctctaaa aagtttgtat gattactttt ctgaatggtt
    16921 aaattatatc atttttaaac tacttgtcaa tagtctatta gaattttttt gatattcact
    16981 tttagcattc actcttgaaa attatcaacc tgaattacgc aatcctgtcg caattccgtt
    17041 gatggtgata tgaatcaatc gttcttgatc actggacaat tctccacgac gttggcgttt
    17101 aatcaactct aactgaatat agttgagaat attaaagtaa ggcatacggt aatccagact
    17161 agcttttaga tatggattgt cagctaagag ttcgtcatgt ccttcaatag ccaagataac
    17221 gttcttagta acttgccatt catttaaaat agtctcatag atggccttaa cttgctcgtc
    17281 ttcacaaagt ttagcatatt caaaagcaat attcatattt gattttgaca aaaccatatc
    17341 aacatttgaa agaagcgatt ggaagaaagg ccaattttgg tacatatctc gtaagatagc
    17401 aatattctct ggatttttat tgataaattc cttgaagctt gaaccaaccc cgtaccatcc
    17461 agggaacata acacgactct gtgaccatga gaatacccaa gggatggcac gcaatccacc
    17521 gatttcagta atagtcttac gagcggctgg acgagaacca atattaaaac ttgaaatagc
    17581 cttgattgga cttgaatcga agaaataatc atagaaatgc tcattaccaa agaccaaatc
    17641 acggtagata tcgtaactac ggtccactac ttgatccata atggcttcat aacgatttgg
    17701 ggtattggta tcgctcttct tctgagtaat catacggtta atagctgccg atactagcat
    17761 ttcaaggtta tagtaagcgg cgtctttgtt accgtattta ttcccaatta cttcaccctg
    17821 ctccgtcaag cggatacgat ccttgataga cttgagcggt tgagatgtaa tggcttcata
    17881 ggttggccca ccaccacgac cgacagtacc accacgacca tggaagaagg taaccttaac
    17941 gccaaattca tctccaatag cagtcaattg ttgttgagcc ttgtagaggg tccaacatga
    18001 tgacaagtaa ccgccatctt tattactgtc agagtagcca agcatgattt cttggtagtt
    18061 atttcgtgag tcaatccatt ttttggcaag gctaagagaa agatattttc tcattgtttc
    18121 ctctgaatga tccaagtctt caattgtttc aaaaagggga acaatctgaa cacgcgccct
    18181 ttccgtatcc accagtccta cttcttttaa cagaatagct aattctagca tatcagaaag
    18241 gctggttgca tgtgaaatga tggtctgacg gatgacatca tctcccaact tatctttcaa
    18301 aacacgagcc gtcttaaaaa tagctaattc ttttgctaat aattctgatt tttctgcgtg
    18361 agtcgcagaa agaattcggg gatcttcttc taattctttc aagagaaggt cacacttttc
    18421 ttcttcgctc aactcgctat aacgagaatg aattcctgct gatttcaaga gttctgccac
    18481 acaggcttca tagacgctag agtcttgtcg catatcaatt gacgctaagt aaaaaccaaa
    18541 tatctctact gcctgcaata attccacaaa atcacctgaa atcaaggact cacccttatt
    18601 ttctagtaga gaatctcgaa tggcaatcaa atccttgtag aaatcattgg cggtttcata
    18661 acgagtccca acttcttcat cctcaatcag ataggtttta gttgcctgaa tttttgattg
    18721 aatatcaaac aaggcacgac ggtaaagctc tttttcgcgg taaatagagt tatccttgga
    18781 ttgacgagcc atttctctga cttgcttgct gacgttgaca atgctagttg aaagagaaaa
    18841 ttcacgataa agttggtaaa tctttttatc atagtagttc atgatgactt cacactgagt
    18901 gagtgcagac tgcttcaagg tctttgctgt aacaaatgga tttccatcac ggtcaccacc
    18961 tatccacata cccatggtga ttggtttagc ctgttttaaa ttcagaccat gcgcttgcgc
    19021 taagcgctta tactccgtcg tcaaatgagg gacagctttc aaaaaggagc tgttgtaata
    19081 ttccatagca ttcgtgattt cgttagtcac ttttaatttt ttctcacgaa tcatgtctgt
    19141 ctgcatgata atttcgatgt aacgacgcaa atcattgtgc catttatctt tattgattaa
    19201 ccccaactta acatcacggt atttacgcaa aagactatga atatgatttg ttaaatccaa
    19261 catacttttg cgttgcactt gtgttggatg ggctgtcaaa acagggacaa cattcaagtg
    19321 ttctaggatc tcaacggcat tttccttttc tgctaccaat ttaatcgttg tagataattt
    19381 acctaaatag tcctgatcaa tattattttg atgattgatt tcataagcta aatccacatc
    19441 ctctgaaata ttaatcaaaa gaggtaagat agagaaatag cgtgaaatat agaccatttc
    19501 atcatttgat aagctagtca ctagacggtt tagaccttga taatcttcct gcgttgataa
    19561 ttctttcaac tgtattattt tttcaaaggt ctctggggca agcatatttt tagtaatatc
    19621 ttccagtaat tctgttagaa tcaagacttc ttctttcaca acacttttat tactataatt
    19681 ttctaatttt tgaagagaca taaactatcc tttctttatc ctacttcaac agaaggttca
    19741 ttggttgatt ttccaattct cggtacaact tagcgcgttt ttcactggca tcaatattta
    19801 agacaaaggc tactgccact gataagacta gaagactatt tccaccctgg gataagaagg
    19861 ggaaagtcac tcctgtagat ggaatcaagc ccgaaatccc tccgatattg acaaatacct
    19921 gaaccaacat catccctccg acaccgagtg caaccatggc attgaaagga ttctccgctc
    19981 ggataccgac caagataatc cgcaaaatca tgaaaaacaa gagagctaaa ataagactgg
    20041 caccaacaaa gccaaattct tcaatcacga tagaaaagac aaagtctgta tgagcttctg
    20101 gcaaataacc tcgtttttca atcgagtttc caagacctag accaaaccaa ccgccattga
    20161 ccatggcaaa ataagaatta gctaactggt gacctgcatc agcacgatcg gcaaaaggat
    20221 taaaaaaggc actaaagcgc ttggctacat agccaaatac tggaattttt gaaaaggtct
    20281 caacaccgat taggctgata gtggtcaaga caaagacaga agtggcagat acgagcgcca
    20341 gaatggttga aaaccagcga taagcgattc cactaactgt atacataatc aaggaaacca
    20401 agactaaaat agtcgcattt cctaaatcag ggaaaattcc caaacttcca atcagaacta
    20461 ggagaacgaa tcgccaatca ttaaaagcac ggggaagcca ttgattttga gtcaaaactt
    20521 gaaaatcata agtagctatt tcttcttgct gtttggagaa tcggtgagct aaataccaaa
    20581 taataatgat ttttaagtac tcagctggct gaatagttac tcctgcaacc gaaatccaac
    20641 cgtatgcccc gtttacggaa ataccaataa aacgagccaa gaacaataaa agcatttcta
    20701 ttaatataac taaaatgatt agtcgctcat ttctcaaaaa atctagtctc aatttataaa
    20761 ttaaggcaat cagtatcaaa ctaacaatcc aaaagattcc ttggtttcga accaactgca
    20821 aggcactctt gccttcttca attaaaatag cactggtggt cgaatagacc acaatcaagc
    20881 ccaaaataga taaaagcaag tagggaatca agatggaata atttaataag tgcctcttac
    20941 taatcttcat agcatcacca ctctactagg atacagataa atctgttcca aattccgttt
    21001 tattttctag ttttgattgc tattatacca ttttttcaga aagaaaaaaa ctcttacctt
    21061 acaatccttc gaattttact gtttttacag aattaaggca gaatttgaaa tcgtaaaacc
    21121 attttgaata agagttgctt caacccattg actccgacgg attaagttgc tttcgtgaat
    21181 gccaaaatca gccgcaattt gttcataagt gctctattct cgcatgtatt gaatagttac
    21241 cataaggaga tcgtctagga ttaatttgct ttttcgtcca ccttttgcgc gtttacgttg
    21301 ataagctgtt tttaacacag ctaacatctc ttcaaaagtc gtgcgctgaa cacctacaag
    21361 gatcttgaaa cggctatcgc ttaattgttt acttgcttca tcatccatag ttttattgta
    21421 ttgtattttt gtttcgcagg aagtctatta ttcctttcgt tccaaggttt ttacgctttt
    21481 tcaagcaatc ctacacactc cacgtgatgc gtctgtggaa ctcaaaaggt tcggggaacc
    21541 ttttgaggat taattgcgtt tctctaacaa actcacacat tcaacgtggc atgactgatg
    21601 aagtcatcat aagaatttca cttgctgctc tttctcggtg gcagcctgaa cggtcagaag
    21661 tatcattgta tatcatttgt atcatggcat ataaagtatc gctctatttt attgatggtt
    21721 ttaatatcgc tcttatcatg gcgaaccatt caaatctgct ccacaaatga ggaaagtacc
    21781 attttggact attcaattgt caaagaacaa ataaaaaaaa tcttcgcatt ttcacactct
    21841 atgaaattga ggagattatt ttctaaagcg aattttatca ggaaaatccg tcaatcccaa
    21901 taggtagtct gtactgacat cgtaaaagtt tgagagagtt accaatatat ctgctgttaa
    21961 cgtatgctca ccccgttcaa ttttagcata agctgagtct gtaaacgaaa gtattttagc
    22021 tatttgtttt tgggtcaaat cgtgatcttc cctcaaatct ctcaaacgtc tgtacatcta
    22081 gctttctcct gagaaaagta taatatataa aactaagaaa tcattcaaag tgtccaaact
    22141 ggacattttg aactaaaatt aatttattaa acatatctca taagcatatc tattataggt
    22201 aagacaatat taagaaagac ggtcaaaatc tattaaccgt ctaaagatgt tataagctat
    22261 taaaaaatca gcagtaatcc ggtaacaaaa gtcacataat tttgttaagg aagggattaa
    22321 tgatgtccag attactacta accagcaaat tgaaaaatgg tcaacatgat atttctaatg
    22381 tgaatctctt actttcagaa cctaaaagtt gaataatagc caccccctac ttatcaataa
    22441 aattttccgt tgcattaaca gatgtatata gaccactcca tggatttcaa agcaattaac
    22501 tagactttat ttgtcaataa ccacaaaatt agattagaaa aatcattaaa aattaattgg
    22561 agtcctttgt gatgcttttt caataaaagt aatacttctc aatattttaa ctgaactaaa
    22621 gaaatagcat aatggtatct tgattgtatt cttctaaaaa ggattgccct tcacattcaa
    22681 ctgtgattga ttaaattcca aaaatatatt ccaaaggcgc tctaaattct ctatatcagc
    22741 tattttttat catctatcaa cttctatcat acctcttcaa tagcgtgcta aatattagcg
    22801 ataatatcgt aatagataca ccaataataa aaaaattaaa agtattgtta ggatttaaaa
    22861 ctactgagaa aaaaacagta cctagtggca taaaaagaat agctaccgta aagatgattc
    22921 caaatactct gccaagaaac tcattatcta cgtctctttg aacaatagag aaaaattgga
    22981 tattaaaaat ggaaagaaat agactaaata atgctggagt aaaggctaaa ataatgacgt
    23041 tgcggaacat ataatagatc ggcgctgtta gcattaacat caaacctgaa tatgctaaaa
    23101 agagcattaa acgtttgctt gacaaggatt tattgataaa tccacttaat atcgcaccaa
    23161 taaagccacc aatcgcttcg gctgttaaaa aggttccata tagcccactt gaaatacttc
    23221 caaacatttg attactgtat ggcagcaaca aattataggc tgctaggaaa aagttaacaa
    23281 gtgctgaaag ggcaattata gtgagaattt gtttatgact atatacatac gtaaatccta
    23341 tttttaaatc atcaaagatt cctcttatcg tcatattctc ttttgtatcc acctcctcat
    23401 ttacaggagt aatgaagaaa attagtgagg cagcaattaa aaacgataat ccatctagta
    23461 ataacacacc atgtattcca agtaacttat ataagaaaat tgcaatcata ggaattgtta
    23521 ctttaatcac agtacttgtt gtttctagca atgaattaag ttatgatata ctgtcctttt
    23581 ttacaatttc tttcgtaaaa gctttgtatg atggccctga aaaagcactc ataaaagcca
    23641 aaatgacatt tgttatgact atcgcataaa ccaaccattt ttcttgggat ataaatgaaa
    23701 gagttatgca agcaatacca cataagatat ttgtagtaat aataattttt ttccgcttga
    23761 aactatctgc aataactcca ccaaataaat taaatagaac acctatcata ctttctaatg
    23821 attgataaat tgcaaccact gatagagatg ttggattaag accagcaaga aaggtattat
    23881 tggcgaaatc aaacatgata tctccgattc gagatatcat cctactagct acaatggata
    23941 gaatattgtg atgttcttct ctaatcattt tattctcccg aatcagtaat cacatattta
    24001 aacttttgtg atatgtgctt aagttcatct aaccttttct caaattcaca actatttttg
    24061 caattaaatt ggaccaacat tgaattttcg actacatttt cagatacttt atagtaagta
    24121 tttggtttaa taaatatgta cacttttttt gcccaagcca attctttttc atcaggtacc
    24181 tcgataacct taccttgctt tctatataaa gcaaacgttg ctgagatatt agcaggtcta
    24241 gaaatcactt tagaaaaatt tatttttttc aatccttgtg aattagtcaa aatatcccaa
    24301 tattctttaa ttacatcaac tccatgacta tcctcaatta actggggaat atctccccct
    24361 ccaaatcttt ttccaacttc acaaaagact attttaccag ttgataattc aaggaaccat
    24421 tcaaaatgaa aaggggttat ttcagaattg atagaaaaaa cattcaaaac tttgcgacat
    24481 tcttccaatg ctttttctat gtattcaatt ttttcactat cattatataa cgaactagtc
    24541 cttacaagat aatatccact agaacttaag gtattgaaca atagttcctc atattcgtga
    24601 acataaaatc gcttaatctc acttccaatt gaataaccat cacatgttat catgttatcg
    24661 atatcaatgt attcctctat aatatagttt ttttcaaaat acactgaatc aattttctcg
    24721 ttagggtaaa ctttttttat tccattactt cctgcttcat ttctaggttt taaaattgca
    24781 gcagaagatt tacaattatt ccaaaaaaca cgtaaatcat tttctgattc taaaagccta
    24841 aaatacggtt gatttactac tccaactaaa aatgaacgca tgaagtattt gtctttaaat
    24901 aataaattag acacagagtg agtatttttt tctacaaaat gatcattcaa aaaacctact
    24961 atatccatgt cttcctcact caaggttgta atactctcaa cttctgtatt ttgacttatc
    25021 cttctaattt ctaagatgat atttggtaga ataaaatctt ctaaaaaaat gaccttaggt
    25081 agattatttc cttcagctag ataatcttca tatttttttc tttgaacctc aggtgcaata
    25141 attactacat ttctgttata cagatatttt agtttaacaa cccgtgcaga atatctaaat
    25201 aatactatat gcatgttaat cccaatcctt tcaattatta gtcatcatat ccatttggat
    25261 gtttctgttg ccatttccac gtatcttggc acattttcat aatatcatac cttggcttcc
    25321 atcccagtag ctcttctgct tttgaaatat ctgcaattga aacgtccata tctcctgctc
    25381 tccttgaagt tatcttatat ggaatatacg agcctatgac actctctaag ctgtgtagga
    25441 tttcaaatac actaaaacca acaccacttc ctaaattgat tacttcatat aaaccttcat
    25501 ctgtattaaa aatatactct aatgcttttc tgtgtccgta tactaaatcg ttaacgtgaa
    25561 catagtccct tatacaagtc ccatcaggag tactgtaatc aactccgaat atatttaaat
    25621 atggtaattt tccaattgca acttgtgtaa tgtaaggaac aagattattc ggaattccat
    25681 ttggatcctc tcctaaatca ccactttcat gtgcacccaa tggattaaaa tacctcagac
    25741 aaacaatttt ccaatttgaa ttcgaaataa acaaatcatt taaaagtact tctatatact
    25801 gttttgttct cccatacggg tttgaagctt ttaatggatt agtctcatag aatggcatga
    25861 taggagtact ttcgtataca gtagctgatg aactaaacac aaaattaaat accttatatt
    25921 ttttca
//
LOCUS       DBERDS010000026        25256 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.026, whole genome shotgun sequence.
ACCESSION   DBERDS010000026 DBERDS010000000
VERSION     DBERDS010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.026"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            129..284
                     /locus_tag="ACL73E_001251"
                     /pseudo
     CDS             129..284
                     /locus_tag="ACL73E_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            484..3759
                     /gene="rexB"
                     /locus_tag="ACL73E_001252"
     CDS             484..3759
                     /gene="rexB"
                     /locus_tag="ACL73E_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGS0801220.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3756..7406
                     /gene="addA"
                     /locus_tag="ACL73E_001253"
     CDS             3756..7406
                     /gene="addA"
                     /locus_tag="ACL73E_001253"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGS0801221.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDINHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEIFANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7666..8844
                     /locus_tag="ACL73E_001254"
     CDS             7666..8844
                     /locus_tag="ACL73E_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801222.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLMFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLGRLVI
                     "
     gene            9053..14722
                     /locus_tag="ACL73E_001255"
     CDS             9053..14722
                     /locus_tag="ACL73E_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGS0801223.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALPEAVVTDKG
                     EPAVQPELPEAVVTDKGEPEVQPELPEAVVTDKGEPEVQPALPEAVVSDKGEPEQVAP
                     LPEYTRPQAGAVVEPAIQPELPEAVVTDKGEPAVQPELPEAVVTDKGETEVQPESPDT
                     VVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYT
                     GKIEQPSAEDTKPENEASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELYTVENNK
                     YRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAHAENLIQ
                     HENNVISNDYTYYLPKTQQSETGVYTSFNLKKPLFKTLNTATIQNLSIKEANVSSKED
                     AATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTYDTTV
                     GYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYSYVEG
                     NVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAISGDNFDNMKED
                     HAYSSKGNKVVNVVQVDDELVTKDSDVQRGTVLDADKVKEKKAELVSKHSTKVEDFDF
                     TSRYTTIYNEVTGYQKSREQVYKNIEKLLPFYNRETIVKYGNLVDESSELFTKELLSV
                     VPMKNNEVITDINKNKQEINKLLLHFEGNKSQVLNIAYKNDFSKVAEYSIEYQGLLYT
                     PNTLLHDYSNIVDNVLTDLNSVQYDSNAIKKILDISDKVKNTELYLDEQFVKTKANIK
                     DTLSKLLSADAAIAENSNSIIDNYVIQKIKQNKEALLLGLTYLERWYNFKYGETKAKD
                     LVMYHLDFFGKSNSSALDNVIQLGKSGFNNLLAKNNVITYNVLLSKNYGTESLFKALE
                     GYRKVFLPTTSNNEWFKAQTKAYIVEEKSSIPEVSKKQSEQGTKYSIGIYDRLTSPSW
                     KYQSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRSKVHPKGDNLNKFVEDNVREAA
                     KRFRDHYDYWYKILEPENREKLYRSLLVYDAFKFGRDNTEDKVTYQADFETDHPAIKY
                     FFGPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGR
                     RSGLGPEFYAKGLLQAPDHPYDPTITINSVLKYDDSENSTRLQVADPTQRFNSAEDLH
                     NYMHNMFDLIYTLEILEGRAVAKLDYNAKNDLLRKIENKYKQDPDGNSVYATNVVRRL
                     TMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGTPGDL
                     MGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSKIKSYGKEVGLVTDKLVLEKVF
                     NNRYSSWVEFKKAMYNERIAKFNNLISVSFNNPNVSWGRTNRITITSIANLQNMINTA
                     VNEDAEDFRAQLYPDTNSRVLKLKKAIYKAYLDQTNDFRRSIFENKK"
     gene            14766..20060
                     /gene="zmpD"
                     /locus_tag="ACL73E_001256"
     CDS             14766..20060
                     /gene="zmpD"
                     /locus_tag="ACL73E_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpD"
                     /protein_id="HGS0801224.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTEKGEPEVQPALPEAVVTEKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVD
                     ENGNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKF
                     IGDNSVKQVSEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTKEKTAPV
                     LTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQ
                     NLDWFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTE
                     TPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLI
                     QHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPT
                     PKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRI
                     APIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQ
                     FLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVK
                     GTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRG
                     NYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRL
                     TRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVT
                     GMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNM
                     VEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYIKDLYLEESFA
                     ETKANLDKLVKSLVENADHQLNSDETAMKALVKKVDENKAKIMMALTYLNRYYDIKYG
                     DMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELH
                     GFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRM
                     ILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFW
                     SRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTW
                     KFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGH
                     RHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTRE
                     DIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPH
                     QWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMA
                     GIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDF
                     IIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTE
                     DLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
     gene            20227..21573
                     /locus_tag="ACL73E_001257"
     CDS             20227..21573
                     /locus_tag="ACL73E_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGS0801225.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFRLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSCLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKMDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            21988..22839
                     /gene="ylqF"
                     /locus_tag="ACL73E_001258"
     CDS             21988..22839
                     /gene="ylqF"
                     /locus_tag="ACL73E_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGS0801226.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            22826..23605
                     /locus_tag="ACL73E_001259"
     CDS             22826..23605
                     /locus_tag="ACL73E_001259"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGS0801227.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            23621..25171
                     /locus_tag="ACL73E_001260"
     CDS             23621..25171
                     /locus_tag="ACL73E_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGS0801228.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGVICVNLRLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         8448 a         4565 c         5168 g         7075 t
ORIGIN      
        1 actatattag attgaaataa gatacgaaca gcttgattag ggaaatcaaa ttaatttcta
       61 gaaatatttt agcatccacg atgtactatt atagtttcaa tttactatag ttcaatcatt
      121 ctatcaagaa tattgaatat ataaaggcac gtaatattaa aacttcttct gatatcgaat
      181 tagagtccga tgttgatggc gataaatcag acaatctacc cgtcgacatt aagatactgg
      241 gacaacacat tgaagtgtat tccgtaccta agaaacaatc ataaaactca aagtcttgtt
      301 accgaggctt ttttattatg tgattttcag tagccagact tattctatct aatacaagta
      361 aagctaagta tttaagattt agcagatgat gaagaaaaga aaggatggcc taaatatttt
      421 aacagattta cgaggctaat catggtataa tatagggtga tgaaaaattc caacgaggct
      481 gagatgaaat tactttatac tgatattcga acttctttga cagaaattct aacaagagag
      541 gcagaagagc tagttgcagc tggcaagcgg gtcttctaca ttgcccccaa ctctctttct
      601 tttgaaaagg aacgcgccgt gctggaatgc ttgtcccagc aggcttcttt ttctattacc
      661 gtcacgcgct ttgctcaaat ggctcgttat ctggtcctga atgatttacc agttaaaact
      721 actcttgatg atatcggtct tgggttggcc ttttacaaat gccttgccga actcgatccc
      781 aaggacttgc gtgtttatgg cgctattaag caggatcctc aattgatcca gcagttaatt
      841 gagctttacc atgagatgac caaatctcag atgagttttt tggacttgga gaatttaaca
      901 gatgaggata agaggacgga tttactcttg atttttgaga aagtaacagc ctatcttaat
      961 caaggtcagt tagcccaggg aagtcagttg tcccatttga ttgaggctat tgagaatgac
     1021 aaggtaagta gtgattttaa tcaaatcacc ttggtcattg acggctttac tcgtttttct
     1081 gctgaggaag agcgggttgt ggacttactt cacggcaaag gtgttgagat tgttatcggg
     1141 gcttatgcta gtaagaaagc ctataccagt ccttttagcg agggcaatct ctaccaagcc
     1201 agcgtaaaat ttctccatca tctggcttct aaataccaaa cgcctgctca ggactgttct
     1261 caaactcatg agaagatgga tagttttgac aaggcctctc gtttgttgga gtcttcttat
     1321 gacttttcag aactcgcttt ggatgtcgat gagaaagacc gtgaaaattt acaaatctgg
     1381 tcttgtttga cgcaaaagga ggagttggag ctagtagccc gtagcattcg tcagaaatta
     1441 catgagaact cagacctgag ctacaagcat tttcgtattc tcttggggga tgtagcttct
     1501 taccagttat ctctcaaaac catttttgac cagtatcaga ttccttttta tcttggtaga
     1561 agcgaagcca tggctcatca tcccttgact cagtttgtcg agtctatttt agctttaaaa
     1621 cgttaccgtt ttcgtcagga ggatttgatt aatcttctta gaactgattt gtatactgac
     1681 ctcagtcagt ctgatattga tgcttttgag caatatatcc gctatcttgg tatcaatggc
     1741 ttgccagcct ttcagcaaat cttcaccaaa tcccaccatg gaaaatttaa tcttgagcgt
     1801 ttgaatgtcc tccgcctgag aattttagca cctcttgaaa ccctctttgc cagccgaaaa
     1861 caaaaggctg aaaacctcct acaaaaatgg agtgtctttc taaaagaagg agctgtgacc
     1921 aagcagttac aagatttgac aaccactttg gaagctgtag aacaggaaag acaagccgaa
     1981 gtttggaagg ctttctgcca tgttttagaa caatttgcga ctgtttttgc tggttcacag
     2041 gttagtctgg aagacttcct agccttgctc cattctggaa tgagtttgtc ccaataccgt
     2101 accattccag caacagtgga cactgttctg gtgcagagtt acgatttgat tgcaccattg
     2161 actgctgact ttgtctatgc tattggacta actcaggaca atttaccaaa aatttctcaa
     2221 aacaccagtc ttctgacaga tgaagaaagg caaaatctaa accaagcgac cgaagaaggc
     2281 gttcaattac tgattgccag cagtgaaaat ctcaagaaaa atcgctacac tatgctttcc
     2341 ttggtcaatt ctgctcgtaa gcagttgttc ttgtcggctc caagcctttt taacgaaagt
     2401 gaaagtaagg aatctgccta tcttcaagag ttgatccatt ttggatttag gcggagagag
     2461 aagaggatga atcacaaagg actgtctaag gaggatatgg ggtcctatca cagtcttttg
     2521 tctagtctgg ttgcctatca ccagcagggt gagatgagcg atactgagca agatttgact
     2581 tttgtcaagg ttctgtcgcg tgtcataggt aaaaaactag atctgcaagg tctggaaaat
     2641 ccagctatcc caaccagtcc aagcagcaag accttagcca aggacacctt gcaagctctc
     2701 tatcctgcca aacaggagtt ttacctgtct acgtcgggtt tgacagagtt ttatcgcaat
     2761 gaatacagtt atttcctacg ctacgtttta ggcttgcagg aggaattacg tttgcgtcct
     2821 gatgcccgta gtcacgggaa tttcttgcat cgtatctttg aacgcgcctt acagttgcct
     2881 aatgaagatt cctttgacca acgtctagaa caagctattc aagaaaccag tcaagaacgc
     2941 gaatttgaag ctatttatca agaaagtttg gaagcccagt ttaccaagga agttttgctt
     3001 gatgttgcac ggacgactgg acatattctc cgacacaatc cagccatcga aaccatcaaa
     3061 gaagaagcaa attttggtgg aaaagaccaa gcctttattc aattagacaa tggacgcagt
     3121 gtctttgtac gaggcaaggt ggaccggatt gaccgtttga aagctaatgg agcgatagga
     3181 gtagtagact acaaatccag tctgactcag ttccagtttc ctcatttctt taatgggctc
     3241 aattctcagt taccaaccta tcttgctgcc ctaaaaagag aaggggagca gaactttttc
     3301 ggcgccatgt acttggaaat ggctgaacct gtccaatctc tgatggcggt aaaaagtctg
     3361 gcaggagcag tggtagaagc cagcaaatct atgaaatacc aagggctctt cttggaaaaa
     3421 gaaagcagtt atttaggcga attttataac aaaaacaagg ctaatcaact gacagatgag
     3481 gaatttcagc tcctactgga ctacaatgcc tatctttaca agaaagctgc tgagaagatt
     3541 ttagcaggcc ggttcgccat caatccttat actgaaaatg gcagaagcat tgccccatac
     3601 gtccagcaac atcaggctat tacaggcttt gaagccaatt accatctggg ccaagcccgt
     3661 ttcctagaaa agttggacct agctgatggc aagcgtctgg tcggagaaaa actcaagcaa
     3721 gcttggtttg aaaaaataag agaggagtta aatcgatgaa gcttattccc tttttaagtg
     3781 aggaggagat tcaaaaactg caagaagcag aagcaaattc gagcaaggaa cagaagaaaa
     3841 ctgccgaaca aatcgaagct atctacactt ctggtcagaa tatcctggtc tcagcatcgg
     3901 ctggttctgg aaagaccttt gtcatggtag agcgcattct ggaccaattg gcgcgtggtg
     3961 tcgaaatttc tcaactcttt atctcaacct ttaccgtcaa ggctgcaact gaacttaaag
     4021 aacgtttaga gaaaaaaatc agcaagaaaa tccaagaaac agatgatgtc gatctcaaac
     4081 aacacttggg tcgccagttg gcagacctac ccaacgctgc catcggaacc atggactctt
     4141 tcacacaaaa attccttggc aaacatggtt atctgcttga tattgcacct aatttccgta
     4201 ttttacaaaa ccaaagcgag caacttcttc tcgaaaacga agtctttcat gaggtctttg
     4261 aagcgcatta ccaaggtaaa cagaaagaga gctttagtca tttgctgaaa aactttgctg
     4321 ggcgtggcaa ggacgaacgg ggtctgcggc agcaagtcta taaaatctat gacttcctcc
     4381 aatccaccag taatcctcaa aagtggctga gtgaatcttt cctcaaaggc tttgagaaag
     4441 ctgattttac cagtgaaaaa gaaaaactga ctgagcaaat caaacaagcc ctctgggatt
     4501 tggaaagctt tttccgttac catctggata acgatgccaa ggagtttgca aaggctgcct
     4561 atttagaaaa tgttcagtta attctggatg aaattggctc cctaaatcag gagttcgata
     4621 gtcaggctta tcaggcagta cttgcgcgtg ttgtcgccat ctctaaggag aaaaacggtc
     4681 gagctctgac taatgccagc cgtaaggctg atttgaagcc cctggctgat gcctacaacg
     4741 aagagagaaa gacccagttt actaaactag gacaattatc agaccagata gcgattctcg
     4801 actatcaaga acgttatcat ggagacactt ggaaactagc taaaaccttc caatctttca
     4861 tgagcgattt tgtagaggct tatcgtcaga gaaaacgaca ggaaaatgcc tttgaattcg
     4921 ctgatatcag ccattacacc attgagattt tagaaaattt cccacaagtt cgtgagtctt
     4981 atcaggagcg cttccatgaa gtcatggtcg atgagtatca ggatatcaac catattcaag
     5041 aacggatgct ggaattgttg tctaatggcc acaatcgctt tatggtggga gatatcaagc
     5101 aatccatcta tcgtttccgt caggcagacc cgcagatttt caatgagaaa ttccaacgct
     5161 atgcgcaaaa tcctcaagaa ggcaagctca ttctcctcaa ggaaaatttc cgtagtagtt
     5221 cagaagtgct gtcagcaacc aatgatgtct ttgaacgtct catggaccaa gaggtcggcg
     5281 aaatcaacta tgataacatg caccagcttg tttttgccaa taccaaactg actcccaatc
     5341 cagacaacaa ggccgaattt ctcctctacg acaaggacga tacaggtgag gaagaagaga
     5401 gtcaaacaga aacgaaacta acaggcgaaa tgcgcttagt tatcaaggag atccttaaac
     5461 ttcatcagga aaaaggtgtt gcctttaagg aaattgccct tctgacctct agtcgtaatc
     5521 gtaatgacca aattctactt gccctgtctg agtacgggat tcctgtcaaa actgacggag
     5581 agcaaaacaa ttatctccaa tccctagaag tgcaagtcat gctagacacc cttcgtgtca
     5641 ttcacaatcc cctgcaagac tacgccttgg ttgcccttat gaagtctcca atgtttggtt
     5701 ttgatgagga tgagctagca cgtttgtccc ttcagaaagc agaggataaa gcccacgaaa
     5761 atctctatga gaaactagtc aatgcacaaa aaaaggcaag tagtcaaaaa ggcttgattc
     5821 acacagctct agctgaaaaa ctaaagcaat tcatggatat cctagcttct tggcgcttgt
     5881 atgccaaacc ccactctctc tatgacttga tttggaagat ttacaacgac cgtttttatt
     5941 atgactatgt tggggctttg ccgaatggtc ctgctaggca ggccaatctc tatgccctag
     6001 cactgcgtgc tgatcaattt gaaaagagca atttcaaagg tttgtcgcgt tttattcgta
     6061 tgattgacca agtcttagaa gcccagcacg atttggcaag cgtggccgtc gcaccgccaa
     6121 aagatgcagt agagctcatg accatccaca agagtaaagg gctggagttt ccttacgtct
     6181 ttatcctcaa tatggatcaa gatttcaaca aacaagactc tatgtcagaa gtcattctca
     6241 gtcgtcagaa tggtcttggt gtcaaatata ttgccaagat ggagacaggg gcagtagaag
     6301 accactatcc taaaaccatc aaactctcca ttcctagtct gacctatagg cagaacgaag
     6361 aggaattaca gctagcaagc tattctgagc agatgcgttt gctgtatgtt gctatgacgc
     6421 gggctgagaa aaagctctat cttgtcggca agggttctcg tgaaaagctg gaatccaagg
     6481 aatacccagc agccaaaaat gggaaactaa atagcaatac tagactgcaa gcacggaatt
     6541 tccaagattg gctttgggct atcagtaaag tgtttactaa ggacaagctc aactttagtt
     6601 atcgttttat tggcgaagat cagttgacca gagaagctat cggagagttg gaaaccaaga
     6661 gtcctctcca agatagctcc caagcagaca atcgtcagtc agataccatc aaagaagctc
     6721 tggaaatgct gaaggaggtg gaagtttata atactcttca ccgcgcagct attgaacttc
     6781 ctagtgttca aaccccaagt caaatcaaga aattctacga accagttatg gatatggaag
     6841 gtgtcgagat tgctggtcaa ggtcagtcag taggcaagaa aatcagcttc gatttgccag
     6901 atttttcaac caaagaaaag gtaactggag ctgagattgg tagtgctact cacgaactca
     6961 tgcagagaat tgacctcagc cagcaactaa cccttgctag cctaacagaa acactcaaac
     7021 aagttcaaac tagccaagct gtcagagaca agatcaatct tgataaaatt cttgctttct
     7081 ttgacacagc actcggtcag gaaatttttg ctaataccga ccatctctat cgcgagcaac
     7141 ctttctccat gctcaaacga gaccaaaaga gtcaggaaga ctttgttgtc cgtggtatcc
     7201 ttgatggcta tctgctttac gaaaacaaaa ttgttttgtt cgactacaag acagaccgct
     7261 atgatgaacc aagtcaactc gtagaccgct atcgtggtca gttagctcta tacgaagagg
     7321 ctttatcacg agcctattcg attgaaaata ttgaaaaata cttgatttta ctcggtaaag
     7381 acgaggttca agttgtaaaa gtataactta tactcttcga aaatctcttc aaaccacgtc
     7441 agcttcgcct tgctgtatat atggttactg acttcgtcag ttctatccac aacctcaaaa
     7501 cagtgttttg agctgacttc gtcagttcta tccacaacct caaaacagtg ttttgagctg
     7561 acttcgtcag ttctatctac aacctcaaaa cagtgttttg agctgactgc ggctagcttt
     7621 ctagtttgct ctttgatttt tattgagtat tagaaaggag acctcatgac acttccagtt
     7681 agaaaatccc tgcacgatgc agttttacag gcttcgaaag cggatacttg ggaacaagct
     7741 accaaggaat ggaatgaagt ttccttgatg tttaacggta tcggccgtag caattgtgtc
     7801 tgtggaaatg ccatcaaata cgcttatgaa ctctttaacg gtgtcacagg ccaacgcctc
     7861 tttccaattg gtagcgactg tgttcgtcat tttcatcgat tgtcccttga ccagcaattg
     7921 gaagaggaag aaaaactgct cagaaaggtt gaaaatctaa ccagaaaagc tcagaaaaag
     7981 gaaaaaatca aggtcaataa aagtgacttt gacgagcgac ttctaaaatg gctctgggaa
     8041 aaaggtgttt tcaaacccaa tcgtggcaat caatttgcgc ctgagagaga ctaccagctt
     8101 ttcctagaag tctttcaggg aggaagttgg accaaggcgg aaccaaagaa aaaggctcgg
     8161 atggaagaag tccttgaaaa gtgtatcaaa ccatttttac ttgggaaatc ggatgaccaa
     8221 ctctaccttg tcaagctagg caaggagaaa attgactacg aacaagaact ccgtatccag
     8281 gcagagaaag aacgcaagaa gagggataaa atcgccaagc aatatgcaga taatctggtt
     8341 ctagccatgg gacccgcaga gcgtgcttat caagattact ttggctttac agagaccctg
     8401 actcaagaag aacgcaagtg ggaaaaaatt ctttttggta aaaatagagc agaacgggct
     8461 atcaaggcca aacaatacca aaaagagctg gaaaaagacc aacgaattgc cagtcaggat
     8521 ccaattgaaa gaaaacagaa gcagacttgg ctcctcaatt cctattttcg agagcttcct
     8581 gaagaaaaag ctcgattttc taggctctta ttagaatatc gaaaaagtgg tgaagtaccc
     8641 ttttcaactg aatacctgtc agatcatctc atcgactttt tctataaaat gaaagccttt
     8701 gaatttgaaa tcgcaccaga acaagtccga gattttctaa aaaaaagcct gcaggaagac
     8761 catcgctcat cagcacaagg aagctggata gaaggaattc tcctcaactg cctcaaacca
     8821 tttttaggac gattagtgat atgagtaaca cctaccgtgt aaatttcatg gtaggtgtta
     8881 ttgtacccca aaataatata aaacaaagta tgaaagcgca tctcaatttt aagacttttt
     8941 tgtaaattaa gagtataatt aaggtatact gccttttcta tagataatag ataatacact
     9001 aatataataa aggtctttgt aacatatata aattttattt caaggaggaa taatggaaaa
     9061 gtattttggt gaaaaacaag agcgtttttc atttagaaaa ttatcagtag gacttgtatc
     9121 tgcaacgatt tcaagtttat tttttatgtc tgtattagct agttcatctg tggatgctca
     9181 agaaactgcg ggagttcact ataaatatgt ggcagattca gagctatcat cagaagaaaa
     9241 gaagcagctt gtctatgata ttccgacata cgtggagaat gatgatgaaa cttattatct
     9301 tgtttataag ttaaattctc aaaatcaact ggcggaatta ccaaatactg gaagcaagaa
     9361 tgagaggcaa gccctagttg ctggtgctag cttagctgct ctgggaattt taatttttgc
     9421 tgtttccaag aaaaaggtta agaataaaac ggtattacat ttagtattgg ttgcgggaat
     9481 aggaaatggt gtcttagttt cagtccatgc tttagaaaat catcttttgc taaattacaa
     9541 tacggactat gaattgacct ctggagaaaa attacctctt cctaaagaga tttcaggtta
     9601 cacttatatt ggatatatca aagagggaaa aacgacttct gattttgaag taagtaatca
     9661 agaaaaatca gcagccactc ctacaaaaca acaaaaggtg gattataatg ttacaccaaa
     9721 ttttgtagac catccatcaa cagtacaagc tattcaggaa caaacacctg tttcttcaac
     9781 taagccgaca gaagttcaag tagttgaaaa acctttctct actgaattaa tcaatccaag
     9841 aaaagaagag aaacaatctt cagattctca agaacaatta gccgaacata agaatctaga
     9901 aacgaagaaa gaggagaaga tttctccaaa agaaaagact ggggtaaata cattaaatcc
     9961 acaggatgaa gttttatcag gtcaattgaa caaacctgaa ctcttatatc gtgaggaaac
    10021 tatagagaca aaaatagatt ttcaagaaga aattcaagaa aatcctgatt tagctgaagg
    10081 aactgtaaga gtaaaacaag aaggtaaatt aggtaagaaa gttgaaatcg tcagaatatt
    10141 ctctgtaaac aaggaagaag tttcgcgaga aattgtttcg acttcaacga ctgcgcctat
    10201 tccaagaata gtcgaaaaag gtactaaaaa aactcaagtt ataaaggaac aacctgagac
    10261 tggtgtagaa cataaggacg tacagtctgg agctattgtt gaacccgcaa ttcagcctga
    10321 gttgccagaa gctgtagtaa gtgataaagg cgtaccagaa gttcaaccag cgttaccgga
    10381 agcagtcgta accgacaaag gtgagcccgc tgtccaacct gaattacccg aagctgttgt
    10441 aactgacaaa ggcgagcctg aagttcaacc tgaattaccc gaagctgttg taactgacaa
    10501 aggcgagcct gaagttcaac cagcgttacc cgaagcggtt gtaagtgata aaggtgaacc
    10561 agagcaggta gccccattgc cagaatatac aagaccacaa gcaggtgcag tagttgaacc
    10621 tgcaatccaa ccagagttac cagaagctgt tgtaactgac aaaggagaac cagcagtcca
    10681 accagagcta ccggaagcgg ttgtaactga caaaggtgag actgaggttc aaccagagtc
    10741 gccagatact gtggtaagtg ataaaggtga acctaaacag gtagcaccgc ttccagaata
    10801 tacaggacca caagccagcg ctattgttga accagagcaa gtagcaccac taccagaata
    10861 cacaggggta caagccggat cgatagtcga gccagagaaa gtagaagcac cgaaagaata
    10921 tactggtaaa atcgaacaac ctagtgcaga agatactaaa cctgaaaatg aggcaagctc
    10981 tacaaatggg gaatcggaac gtcctaaaga taaaattaaa gaagaaaaac aagtcgacaa
    11041 gaaactagaa cttagaaatg tttcaaacgt ggaattatat acggtagaaa ataataaata
    11101 tcgacatatt acggctgtag atggtgcttt agatagttca ttgaagtatt tcatgaaggt
    11161 aaaatcagaa aattttaaag atataatgtt gcctgttact aaaattgaaa gtacaacaaa
    11221 aaacaataaa gaagtataca aaattgtggc tcatgcagaa aatctaattc aacacgaaaa
    11281 caatgttatt tcgaatgact atacatatta tttaccaaaa actcagcaaa gtgaaactgg
    11341 cgtctataca tcatttaact tgaaaaaacc tttatttaaa actctaaaca ccgctactat
    11401 tcagaatctt tcaataaaag aagcgaatgt ttcttctaaa gaagatgctg ctacaatatc
    11461 gaaagaagca aaatacaata ctcttataga taatgttcat tctgatggta ttatagctgg
    11521 tgaacgtgga attggtggat tggtttcaaa agtagataac tcgagaattt ctaatagtag
    11581 ttttacaggc agaataacta acacatatga tacaactgta gggtatgaaa ttggtggttt
    11641 agtaggtaaa ctttctggtt cgcttgcttc tatagagaaa tcaatagcat cgattgacat
    11701 agcctctaat gcaaaatcag gagatcaaat tgttggtggt atagccggag ttgttgagaa
    11761 aagtgcgaca attaagtata gctatgttga aggaaatgtt aacaatgtgc gacactttgg
    11821 taaagttggg ggagttgcag gtaatctttg ggatagagat tcacaagatg taagtaaatc
    11881 aggtaaacta tcatatgttt taagtgatgt taatgtaaca aatggtaatg ctatatcggg
    11941 tgataatttt gataatatga aagaagatca tgcttatagt agtaaaggca ataaagtagt
    12001 aaatgtagtc caagtagatg atgaacttgt gactaaagat tcagatgtac aaagaggtac
    12061 ggtattagat gctgataaag taaaagagaa aaaggcagaa ttggtttcca aacacagcac
    12121 taaagtagaa gattttgatt tcacttcaag atacactact atttacaatg aagtaacagg
    12181 ttatcaaaag tcgagagaac aagtatataa aaatattgaa aaactattac cgttctataa
    12241 tcgagagaca attgttaaat atggtaattt agtagatgaa agcagcgagc tatttactaa
    12301 agaacttcta tcagttgttc ctatgaagaa taatgaagta ataactgata ttaataaaaa
    12361 taaacaagaa ataaacaaat tgttattaca ttttgaaggt aataaatcac aagtattaaa
    12421 tattgcatat aagaatgatt tctctaaagt tgctgagtat agtatagagt atcaaggatt
    12481 attatatact cccaatactc tattgcatga ctacagtaat attgtagata atgttttaac
    12541 tgacttgaat tctgtacaat atgattcaaa tgcaattaag aaaatattag atatctcaga
    12601 taaagttaaa aatacggaat tatacttaga tgagcaattt gttaaaacaa aagcaaatat
    12661 aaaagatact ttatcaaaac ttctgtcagc ggatgcagca atcgctgaga atagtaattc
    12721 gataattgat aattatgtta ttcagaaaat caaacagaat aaagaagctt tattgttagg
    12781 attaacatac ttagagcgtt ggtacaattt taaatatggt gaaacgaaag caaaagattt
    12841 agttatgtat cacttggatt tcttcggtaa atctaatagt tctgcattag ataatgttat
    12901 tcaattaggt aaatctggat ttaacaattt actagcaaaa aataatgtaa ttacttacaa
    12961 tgtattatta tctaaaaatt atggaactga aagtttattt aaagcattag aaggatatag
    13021 aaaagtattc ttaccaacaa cttctaacaa tgagtggttt aaagctcaaa ctaaagcata
    13081 tattgttgaa gaaaaatctt ctattccaga agtaagtaaa aaacaatcag aacaaggaac
    13141 taagtattct ataggaattt atgatagatt aactagtccg tcatggaaat atcaaagtat
    13201 ggtcttacca ctattaactt tacctgaaga aaaaacagta tttatgatag cgaatatttc
    13261 aacaatagga tttggtgctt atgatagata tagaagtaaa gtccatccta aaggagataa
    13321 cttaaataaa tttgtagaag acaatgtaag agaagctgca aaaagattta gagatcatta
    13381 tgattattgg tataaaatat tagagcctga gaatagagag aaactttata gaagtttatt
    13441 agtatacgat gcatttaaat ttggtcgaga taatactgaa gataaagtaa cttatcaagc
    13501 tgattttgaa actgatcatc cagctataaa atacttcttt ggacctgcgg ggaataatgt
    13561 tgttcataat ggacacggag catatgctac cggagatgca ttctattata tggcatatcg
    13621 tatgttggat aaagatggag ctgtaacata tactcatgaa atgacacata actctgatag
    13681 agaaatttat cttggaggat atggaagaag aagcggatta gggcctgagt tttatgctaa
    13741 gggcttatta caagcacctg accacccata tgatccaaca ataacaatta actctgtgtt
    13801 gaaatatgat gattcagaaa attcaacaag acttcaagta gctgatccaa ctcaacgatt
    13861 taatagtgca gaagacctac ataattatat gcataatatg tttgatttaa tatatactct
    13921 tgaaatatta gaaggtcgtg ctgtagctaa attagattat aatgcgaaaa atgatttatt
    13981 aagaaaaatt gagaataaat ataagcaaga tccagatggt aattctgttt atgcgacaaa
    14041 tgttgttcgc agattaacga tggatgaagt taataaatta aattcttttg atagtttaat
    14101 tgaaaatgat attattacta gcagagggta caaagaccaa gaatataaga gaaatggtta
    14161 ttatacaatt gatttatttt caccgattta ttcagctctt agtggagaga aagggactcc
    14221 tggtgattta atgggacgtc gtatagcatt cgaattatta gctgcaaaag gatataaaga
    14281 gggcatggta ccttatatct caaatcaata tgaaaaagat gcaaaagctg cgggaagtaa
    14341 gattaaatct tatggtaaag aagtaggttt agttacagat aaattagtac ttgaaaaggt
    14401 atttaataat cgttactcat cttgggtaga atttaaaaaa gcaatgtata atgagcgaat
    14461 agctaaattt aataatctaa taagtgttag ctttaataat ccaaatgtaa gttggggaag
    14521 aactaataga ataacaataa ctagcatagc caaccttcaa aatatgataa atacggctgt
    14581 caatgaagat gctgaagatt ttagagcaca attataccct gatacaaata gtagagttct
    14641 taaactgaaa aaagcaatat ataaagccta tcttgaccaa acaaatgatt ttagaagatc
    14701 aatttttgag aataaaaaat agtgtttact attaggaaat aaaaagtgaa tgtggaggat
    14761 tagaattgtc attattaaaa aaagataaat tttccattag gaaaataaag ggtattgttg
    14821 gttcgatatt cttggggagt tttttatttg cactgtcagt tgttggtgta tcgacttatc
    14881 attacttaga ttatagtact ttgacacaaa ctgaacgtga tcaactcaaa caaggtagac
    14941 ctgatgaatc aaaagagtca tatgctttgg tttatgaaaa agacgcatta ccaaacacag
    15001 gaagttctca atctattatg actgtattgg gtttgttagc tatagggagt cttattgtga
    15061 ttatcacaaa agataaaaag aggaaaaaaa tagctacatt tttgattgta ggggcgacag
    15121 gtttagttac actatcaact gcttcagcac ttaatttgaa tgctaacatc catgagtctg
    15181 gacgtgatgg tgtgttgcaa atttctggtt acagatatgt tggttacttg gagcttgatg
    15241 atagaactgt ttcgtcggtt tctccagcat caactgtttc tccagttgag caacccaaag
    15301 ttgtgaccga caaaggcgaa ccagaagttc agccagcgtt accagaagca gttgtaactg
    15361 aaaaagggga accagaagta caaccagcct tacccgaagc agttgtaact gaaaaagggg
    15421 aaccagaagt tcatgagaag cctgactata cgcaaccaat aggtgcaaac cttgttgagc
    15481 ctgaagttca tgagaagcct gactatacgc aaccaatagg tgcaaacctt gttgagcctg
    15541 aagttcatga gaaactagca tacactgaac ctgtaggtac aacaggagta gatgaaaatg
    15601 gaaacttgat tgagccacct gttaacgata ttccagagta tactgaacca atatctacag
    15661 tttcagaagt tgcatcagaa agagaagagt tgccttcttt acataccgat attcgtacag
    15721 agactattcc taaaaccact atagaagaat ctgatcctag caaatttata ggcgataatt
    15781 ctgttaaaca agttagtgag gatggcgaac gtcaaattgt tactagctat gaagagttac
    15841 atggcaaaaa aatcagcgag tcagttgaaa cagtaacaat tttgaaagaa atgaagcctg
    15901 aaattattgt aaaaggtaca aaagaaaaaa cggctcctgt tttaaccttg accaaagtaa
    15961 cagaagatgc tatgaatcgt tctgccaact taaattatga gcttgataat aaagataatg
    16021 ctgaaatatc aagtattgta gctgaaatta aagatggtga tacagtagtt aaaagggttg
    16081 atttatctaa agaaaaatta actgacgctg tacaaaattt ggattggttt aaagattata
    16141 agattgcaac aacaatgatt tatgatcgtg gtcaaggttc tgaaacgtct aaactggatg
    16201 aaagacctct gcgtttggag ttgaaaaagg tcgaaattaa aaatatcgca tctactaatt
    16261 tagtgaaggt aaatgatgat ggtactgaaa cacctagtga ttttatgaat gaaaaacctt
    16321 cagaagaaga tgttaaaaaa atgtacttaa aaatcactag tcgcgataat aaggtaactc
    16381 gtttaactgt agactctatt gaagaagtga ctgaagaagg tcaaaaactt tacaaaataa
    16441 ctgctgaagc acaagatttg attcaacaca cagacccaac gaaggttcgt aataagtatg
    16501 tttattatat agaaaaaccc catcctaaag aagataatgt ctactataac tttaaagatt
    16561 tagtagatgc tatgaatact gataaaaatg gtacatttaa acttggtgca gatttgaatg
    16621 ccactggtgt tccaacacct aagaaatggt atgttgacgg cgactttaga ggtacattga
    16681 agagtgtaga ggggaaacat tatactatcc acaacacgga gcgtccgtta ttccagaata
    16741 ttattggtgg tacagtaacc aaagtaaatc tgggaaatgt aaatatcaat atgccatggg
    16801 cagaccgcat cgcaccgatt gctgacacta ttaaaggtgg cgctaaaatt gaagatgtca
    16861 aagtgactgg taacgtatta ggtagaaact gggtatctgg atttattgat aagattgaca
    16921 accaaggtac actcagaaat gtagccttta tcggaaatgt gacatctgta ggtgatggtg
    16981 gtcaattctt gaccggtatc gttggtgaga actggaaagg actagtcgaa cgtgcgtatg
    17041 ttgacgcaaa tcttattggc aagaaagcca aggctgctgg tattgcttat tggacacaaa
    17101 acagtggtga caatcataaa gttggtgtcg aaggtgcagt caagaaagga attgtgaagg
    17161 gtaccattca ggtagaaagt cctgttgaag tcggcggtgc tgttggacgt ttgagtcatc
    17221 atggttatat cggggaagtc gtatctatga tgaaagttaa gaagggtgaa attttttatg
    17281 gttctagtga tatgaatgat gacccatatt gggtggcgaa taatgtacga ggaaattatg
    17341 tcgttaatgg tgtgagtgaa ggtacgatat cttatgctcg tgctaaagaa caccatcgta
    17401 tcaaaccaat ttcacagtca gaagcagata ctaaaattat gatgttaggt attacagcac
    17461 aagattttgc tatcaacgaa cctgtggtca atcgcttaaa ccgtttaacc agaaaagaag
    17521 atgaatataa gtcaacccaa gactataaag tagatcgaga tctggcttat cgtaatattg
    17581 agaaacttca accattttat aacaaagaat ggattgtcaa ccaaggtaac aaacttgcag
    17641 aagattcaaa cttagctaag aaagaagtcc tttctgttac gggtatgaag gatggacagt
    17701 ttgtaactga cttatcagat attgataaga ttatggttca ctatgctgat ggtactaaag
    17761 aagaaatgga cgtcactaag aatgctgatt ctaaagtgaa acaagttcgt gaatatacca
    17821 tcgctggaca aaacgttgtt tatacaccaa atatggttga gaaagaccgt aaccaattga
    17881 ttcaagatat caaagataag ttggcgtcag ttcaattgat ttctcctgaa gtacgtgctt
    17941 tgatggatgc acgtaagaaa ccagaagaaa atactgatga acgtaagaat ggttatatta
    18001 aagaccttta cttagaagaa agctttgctg aaacgaaagc taatcttgat aaattggtta
    18061 aatccttagt tgaaaatgca gatcatcaat taaatagtga cgaaacggct atgaaagcac
    18121 ttgttaagaa ggtggatgaa aataaagcta aaatcatgat ggctctgact tatctcaatc
    18181 gttactatga tatcaagtat ggggatatga ctatcaagaa cttgatgatg tttaaacctg
    18241 atttctatgg taaatcagtt gaccttcttg atttcttgat tcgaattgga tcaagtgaga
    18301 gaaatatcaa aggtgacaga actttggatg cttatcgtga tatgattggt ggaactattg
    18361 gtaagtctga attacatgga ttcttagatt acaatatgcg tctcttcact aacgatactg
    18421 atttaaatga ttggttcatc catgcagcta agaatgtata tgtatcagaa cctcaaacaa
    18481 cgaacccaga ttttgttaat aaacgacatc gtgcatttga tggtttgaac aacggtgttc
    18541 ataatcgtat gattctacct ctattaactc ttaagaatgc acatatgttc ttgatttcaa
    18601 cttacaatac aatggcttat agttcttttg agaaatatgg taagtataca gaagaagcta
    18661 gaaatgaatt caaaaaagaa attgataagg ttgcacatgc tcaacaaaca tacttagact
    18721 tctggtcacg tttagcattg ccaagcgtac gtgaccaatt actcaagagt gagaataggg
    18781 taccaactcc tgtgtgggat aaccaaaact atagtggtat taaaggaata aaccgtatgg
    18841 gttatgatga gaagaaagta ccaattgcgc caattcgtga gttatatggt ccaacttgga
    18901 aattccataa taccaactgg aatatgggag ctatggcatc tattttccca aatcctaata
    18961 acaatgacca agtttatttc atgggaacaa atatgattag tccgtttggt atttcagcct
    19021 ttactcatga aactacacac gttaatgata gaatgcttta cttcggtggt catagacacc
    19081 gtcaaggtac agacgtcgaa gcctatgctc aaggtatgct acaaactccg tcaagtattg
    19141 gtcaccaagg tgaatatggt gctttaggtt tgaacatggc ttatcatcgt gaaaatgatg
    19201 gtgaccaatg gtataactat gaccctgata agcttcaaac tcgtgaagat atcgatcgat
    19261 atatgaaaaa ctataatgaa gcactgatga tgctagatca tgtagaagca gacgccgtac
    19321 ttccacaatt gaatggtgat aatagcaagt ggttcaagaa aattgataga gaaatgcgca
    19381 gaaatcttgg ggatggtttg aataacttag tagcaccgca ccaatgggac aacgttcgtg
    19441 acttaaatca agaagagagt tctaagaaat tatcaagtat taacgatttg attgataata
    19501 atttcatgac caaacacgga aatccaggta acggacgtta tagaccagag gattttagac
    19561 caaactcagc ttacgtaaat gtcaatatga tggcaggaat ttacggtggg aatacgagtc
    19621 aaggtgctcc tggttcatta tcgttcaaac ataatgcctt ccgtatgtgg ggttattatg
    19681 gatatgacaa aggtttcact agttatgtat ctagcaaata tcaaggtgaa gctgataaac
    19741 aaaaccaggg tagattaggt gatgatttca ttatcaaaaa agtttcaaac aaccaattct
    19801 caaatcttga agattggaag aaatattggt atcatgatgt gaaatccaga gctgaaaaag
    19861 gattcacaga gattacaatt gatggacaaa ccattcacaa ctataatgaa ctgaaagact
    19921 tattcgacaa agctgtcaca gaagacctca agaaagctgg aaactactca aatactgaga
    19981 atttgaaatc caaagtcttc aaagctcttc ttaaaaacac agacggtttc tttaatccat
    20041 tgttcaaaaa agacatttaa accccaatta ttcaccccaa atctaaaaac catccagaat
    20101 ccttgcctta gcttagatcc tggatggttt ctttttcacc caatgggtgt tttttactag
    20161 acaaaaaaga gtttcccctt tatggtataa gtgtagaaaa aaaacacaaa aagaaaggaa
    20221 actcacatga acagtttacc aaatcatcac ttccaaaaca agtcttttta ccaactatct
    20281 ttcgatggag gtcatttaac ccagtatggt ggtcttatct tttttcagga acttttttcc
    20341 cagttgaaac taaaagagcg gatttctaag tatttagtaa cgaatgacca acgccgctac
    20401 tgtcgttatt cggattcaga tatccttgtc cagttcctct ttcgactgtt aacaggctat
    20461 ggaacggact atgcttgtaa agaattgtca gctgatgcct actttccaaa attgttggaa
    20521 ggagggcagc ttgcttcaca gccaacctta tcccgttttc tttccagaac tgacgaggaa
    20581 acagtccata gtttgcgatg cctcaacctt gaattggtcg aattcttttt acagtttcac
    20641 cagctaaacc aactcattgt agatatcgat tctacccatt tcacaactta tggcaagcaa
    20701 gaaggtgttg cttataacgc ccactatcgt gctcatggct atcatcctct ttacgctttc
    20761 gaggggaaga caggttattg tttcaatgcc cagcttcgtc ctggtaatcg ttattgttct
    20821 gaagaggcag acagctttat cacacctgtt ttagaacggt ttaatcaact tctctttcga
    20881 atggatagtg gctttgcgac cccaaaatta tacgatttaa ttgaaaaaac agggcaatac
    20941 tacctcataa aactcaagaa aaatactgtt ctgagctgtc ttggagacct ttccctccct
    21001 tgcccacagg atgaggactt aaccatcttg ccccactccg cctactcaga aactctctat
    21061 caagcaggat cttggtcgca caagcgtcgt gtctgccagt tctctgaacg aaaagaagga
    21121 aacttgttct acgatgttat ttctctcgtt acaaatatga cgagtggaac aagccaagac
    21181 cagtttcagc tttatcgtgg acgtggtcaa gccgagaatt tcatcaagga gatgaaggag
    21241 ggattttttg gcgataaaat ggatagttca accttaatca aaaacgaagt tcgtatgatg
    21301 atgagctgta tcgcctacaa tctctatctt tttctcaaac atctagctgg aggtgacttc
    21361 caaactttaa caatcaaacg cttccgccat ctttttcttc acgtggtagg aaaatgtgtt
    21421 cgaacaggac gcaagcagct cctcaaattg tctagtctct atgcctattc cgaattgttt
    21481 tcagcacttt attctaggat tagaaaagtc aacctgaatc ttcctgttcc ttatgaacca
    21541 cctagaagaa aagcgtcgtt aatgatgcat taaagaacag tcgagatgaa aaaatcgtgt
    21601 gacgcaccaa gggaggagtc tgcccttttg aggaaatcta gcgaggaaaa acgatactgg
    21661 aacagcagaa agtaaaactg acctcatgag gacatgaggt caggggtttt gtaagttaca
    21721 tctagttgag agaggtatga atgatttggg ttaaatgttt aaaacataaa gaggacagtt
    21781 ttttgctccc tctgaaaagt catcatttga tggctttttt ctatataggg taaaaggcta
    21841 tcatcggaca aaataaagaa ggcatgatat aatataaagt agatttttat gtcataaaac
    21901 aagaactgtt tggacatcat tcatttttag attgagatct cttagttcta gattaacagc
    21961 ttcagagcta cgaaaggaaa aaactcaatg gctactattc aatggtttcc tggtcacatg
    22021 tctaaagctc gtcgacaggt gcaggagaat ttaaaatttg ttgattttgt gacgatttta
    22081 gtagatgcac gcttgcctct atctagtcaa aatcctatgt tgaccaagat tgttggtgat
    22141 aaaccaaaac tcttgatttt aaacaaggcc gacttggctg atccagcaat gaccaaggaa
    22201 tggcgtcagt attttgaatc acaaggaatc cagacgctag ctatcaactc caaagagcaa
    22261 gtgactgtaa aagttgtaac agatgcggcc aagaagctca tggctgataa gattgctcgc
    22321 cagaaagaac gtgggattca gattgaaacc ttgcgtacca tgattatcgg gattccaaac
    22381 gctggtaaat caactctgat gaaccgtttg gctggtaaaa agattgctgt tgttggaaac
    22441 aagccagggg tcacaaaagg tcaacaatgg cttaaaacca ataaagacct ggaaatcttg
    22501 gatacaccgg ggattctctg gcctaagttt gaggatgaaa ctgttgcact taagttggca
    22561 ttgactggag ctatcaaaga ccagttgctt cctatggatg aggttaccat ttttggtatc
    22621 aattatttca aagaacatta tccagaaaag ctggctgaac gcttcaaaca aatgaaaatt
    22681 gaagaagaac cgtctgtgat tattatggat atgacccgcg ccctcggttt ccgtgatgac
    22741 tatgaccgtt tttacagtct cttcgtgaag gaagtccgtg atggcaaact cggtaactat
    22801 accttagata cattggaaga cctcgatggc aacgattaaa gaaatcaaag aactccttgt
    22861 gacagtcaag gagttagaaa gccctatttt tttagagctt gaaaaggata atcgctcagg
    22921 agttcaaaag gaaatcagca agcgtaaaag agccatccaa gctgaattag atgaaaattt
    22981 gcgcttggaa tccatgcttt cttatgaaaa agaactttat aagcaaggat tgaccttaat
    23041 tgcaggtatt gatgaggttg gtcgtggtcc tcttgctggt cctgtagtcg ctgcggccgt
    23101 tattttacct aaaaattgta agattaaagg tctcaacgac agcaagaaaa ttcctaaaaa
    23161 gaaacatctg gagattttcc aagccgttca agaccaagcc ttgtcgattg gaattggtat
    23221 catagataat caggtcatcg accaagtcaa catctatgaa gcaaccaaac tagccatgca
    23281 agaagcaatc tcccagctca gccctcaacc agagcacctt ttgattgatg ccatgaaact
    23341 ggacttgccc atttcacaaa cctccattat caaaggagat gccaactccc tctctatcgc
    23401 agcagcatct atagtagcca aggtaacacg tgatgaattg atgaaagaat acgatcagca
    23461 gttccctggc tatgatttcg ctactaatgc aggatatggc acagctaaac atctggaagg
    23521 cctcacaaaa ctaggagtta ccccaattca ccgaaccagc tttgaacccg ttaaatcact
    23581 ggttttaggt aaaaaagaaa gttaattgaa aggaaatacc atggaggaac agtcggaaat
    23641 agtccgttct aagaaagaat tcgcctttgc atccagcact atactatccc aagttggtcg
    23701 aggaatcatt gtcggcctca tcgttggaat tatcgtcgga tcctttcgtt tcttaattga
    23761 aaagggcttc cacatgatac aaggagttta tcaagatcaa gggtacttag tgcgcaatct
    23821 ttttgtactg gttttgtttt atatactcat ctgttggctc agtgccaaac taacacggtc
    23881 agaaaaagat attaaaggct caggaattcc tcaagtcgaa gccgaactga aaggcctcat
    23941 gtccctcaac tggtggggca ttctttggaa aaaatatgtg ctaggtattc tcgctattgc
    24001 cagtggactc atgctgggtc gagagggacc cagtattcaa cttggagcag ttggtggtaa
    24061 aggaattgcc aagtggctca aatccagtcc agtagaggaa cgttccttga ttgccagtgg
    24121 agctgcagca ggtttagccg cagcctttaa tgctcctatt gcagcacttc tctttgttgt
    24181 agaagaagtc tatcaccatt tttcgcgctt tttctgggtc tcaactctag cagccagcat
    24241 cgtagcaaac tttgtgtctc tactcatgtt cggtttgaca ccagtattgg atatgccaga
    24301 taacattcct cccatgaccc tagatcagta ttggatatat ctcgtcatgg gaattttcct
    24361 tggattttca ggctttctct atgagaaagc tgtattaaac gttggaagag tttatgactt
    24421 gattggtcaa aaaatccatt tggatagagc ttattatccc atcttggctt ttatccttat
    24481 cataccagtc ggaatcttct tacctcaaat cattggtggc ggaaatcagc ttgtcctttc
    24541 tttaactgaa caaaatttta gtttccaagt tttattagct tactttttga tccgctttat
    24601 ttggagtatg attagctatg gaagtggact gccaggagga attttcctcc ccattttagc
    24661 tcttggttct ttgcttggtg ccttaattgg tgttatctgt gtcaatctta gacttgtcag
    24721 tcaagagcaa ttccctatat ttgtcattct aggaatgagt ggctattttg gagccatatc
    24781 aaaagctccc ttaaccgcta tgatcctcgt aactgagatg gtaggagata ttcgcaacct
    24841 catgccactt ggtcttgtca ctcttgtttc ttatattatc atggatttgc tcaaaggtac
    24901 gccagtctat gaagccatgc tggaaaaaat gcttccagaa gaagtatcta gcgaaggaga
    24961 agttacactt atcgaaatac cagtttctga taaaattgct gggaaacaag ttcatgaact
    25021 caacttacca cacaacgtcc tcatcacaac tcaagtccat aatggcaaga gccaaacagt
    25081 taacggctca accagaatgt atctgggtga tatgattcac ctggttattc caaaaagtga
    25141 aattggaaaa gtcaaagatt tgttgttgta gtacaatcat ttacataatt tatattatgt
    25201 aaatgattgg cttgatttat ttagaaaacc gattctcaga aatgagatcg gttatt
//
LOCUS       DBERDS010000027        23925 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.027, whole genome shotgun sequence.
ACCESSION   DBERDS010000027 DBERDS010000000
VERSION     DBERDS010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.027"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..210)
                     /locus_tag="ACL73E_001261"
     CDS             complement(<1..210)
                     /locus_tag="ACL73E_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGS0801229.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYEAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMP"
     gene            404..901
                     /locus_tag="ACL73E_001262"
     CDS             404..901
                     /locus_tag="ACL73E_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGS0801230.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            901..2556
                     /gene="dnaX"
                     /locus_tag="ACL73E_001263"
     CDS             901..2556
                     /gene="dnaX"
                     /locus_tag="ACL73E_001263"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGS0801231.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2584..2778
                     /locus_tag="ACL73E_001264"
     CDS             2584..2778
                     /locus_tag="ACL73E_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGS0801232.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2928..3698
                     /gene="sufC"
                     /locus_tag="ACL73E_001265"
     CDS             2928..3698
                     /gene="sufC"
                     /locus_tag="ACL73E_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGS0801233.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3726..4988
                     /gene="sufD"
                     /locus_tag="ACL73E_001266"
     CDS             3726..4988
                     /gene="sufD"
                     /locus_tag="ACL73E_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGS0801234.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKDAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4999..6225
                     /locus_tag="ACL73E_001267"
     CDS             4999..6225
                     /locus_tag="ACL73E_001267"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGS0801235.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6212..6652
                     /gene="sufU"
                     /locus_tag="ACL73E_001268"
     CDS             6212..6652
                     /gene="sufU"
                     /locus_tag="ACL73E_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGS0801236.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6706..8118
                     /gene="sufB"
                     /locus_tag="ACL73E_001269"
     CDS             6706..8118
                     /gene="sufB"
                     /locus_tag="ACL73E_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGS0801237.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8349..9590)
                     /gene="pbp3"
                     /locus_tag="ACL73E_001270"
     CDS             complement(8349..9590)
                     /gene="pbp3"
                     /locus_tag="ACL73E_001270"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGS0801238.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9693..10802
                     /gene="cozE"
                     /locus_tag="ACL73E_001271"
     CDS             9693..10802
                     /gene="cozE"
                     /locus_tag="ACL73E_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGS0801239.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGVFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11448..11795
                     /gene="ssrA"
                     /locus_tag="ACL73E_001272"
     tmRNA           11448..11795
                     /gene="ssrA"
                     /locus_tag="ACL73E_001272"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11965..12052)
                     /locus_tag="ACL73E_001273"
     tRNA            complement(11965..12052)
                     /locus_tag="ACL73E_001273"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12016..12018),aa:Ser,seq:gga)
     gene            12214..12954
                     /locus_tag="ACL73E_001274"
     CDS             12214..12954
                     /locus_tag="ACL73E_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0801240.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12951..13862
                     /gene="pfkB"
                     /locus_tag="ACL73E_001275"
     CDS             12951..13862
                     /gene="pfkB"
                     /locus_tag="ACL73E_001275"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGS0801241.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13859..15811
                     /locus_tag="ACL73E_001276"
     CDS             13859..15811
                     /locus_tag="ACL73E_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS0801242.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15948..18200
                     /locus_tag="ACL73E_001277"
     CDS             15948..18200
                     /locus_tag="ACL73E_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGS0801243.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAVFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKEIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(18244..18678)
                     /locus_tag="ACL73E_001278"
     CDS             complement(18244..18678)
                     /locus_tag="ACL73E_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGS0801244.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            18841..20925
                     /locus_tag="ACL73E_001279"
     CDS             18841..20925
                     /locus_tag="ACL73E_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0801245.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKISALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GGLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            20935..21312
                     /locus_tag="ACL73E_001280"
     CDS             20935..21312
                     /locus_tag="ACL73E_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801246.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            21472..22614
                     /locus_tag="ACL73E_001281"
     CDS             21472..22614
                     /locus_tag="ACL73E_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS0801247.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEVLEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            22623..23837
                     /gene="thiI"
                     /locus_tag="ACL73E_001282"
     CDS             22623..23837
                     /gene="thiI"
                     /locus_tag="ACL73E_001282"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGS0801248.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGGDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
BASE COUNT         7082 a         4362 c         5222 g         7259 t
ORIGIN      
        1 aggcatacca gtcgtttcaa gataaggaat tttagaaggt ttttgaaagt catatttctt
       61 catttgactt ccgcactcag gacaagatgg agcttcatag tccagtttgg cgatgatttc
      121 cttgtgtgta tccttattga tgatgtctaa aatctggata ttagggtctt taatgtctag
      181 taattttgtg ataaaatgta attgttccat atgaatcttt ctaatgagtt gtttgatcgc
      241 ttttcattat aggtcatatg ggactttttt tctacacaaa aataggctcc ataatatcca
      301 taggggattt acccactaca aatattatag agcccaaaat cctttgttta ctaaacaagg
      361 gatttttctt ttgtctctgc tccttttttg atataatagt tctatgttaa aatcagaaaa
      421 acaatcacgt tatcaaatgt taaatgaaga attgtccttc ctattggaag gcgaaaccaa
      481 tgttttggct aatctttcca acgccagtgc tctcataaaa tcacgttttc ctaataccgt
      541 atttgcaggc ttttatttgt tcgatggaaa ggaattggtt ttaggcccct tccaaggagg
      601 tgtttcctgc atccgtattg cactaggcaa gggtgtttgt ggtgaggcag ctcactttca
      661 ggaaactgtt attgttggag atgtgacgac ctatctcaac tatatttctt gtgatagtct
      721 agctaaaagt gaaattgtgg tgccgatgat gaagaatggt cagttacttg gagttctgga
      781 tctggattct tcagagattg aggattacga tgctatggat cgagattatt tggaacaatt
      841 tgtcgctatt ttgcttgaaa agacagcatg ggactttacg atgtttgagg aaaaatctta
      901 atgtatcaag cactttatcg aaaatataga agtcaaaact tctcccagtt agttggtcaa
      961 gaagttgtgg ctaagactct taaacaagcg gtggagcaag agaaaataag tcacgcttat
     1021 cttttttctg gtcctcgtgg aacgggaaaa accagtgttg ctaaaatctt tgccaaggct
     1081 atgaactgtc ccaatcaagt gggtggcgaa ccttgcaata actgctatat ttgtcaagca
     1141 gtgacggacg gtagtttaga agatgtcatt gaaatggatg cagcttctaa taatggggta
     1201 gatgaaattc gcgaaattcg tgataaatct acctatgcgc ctagccttgc tcgttataag
     1261 gtttatatca tagatgaggt tcacatgctg tctacagggg cttttaatgc cctcctaaag
     1321 acgctggaag aaccaacaca gaatgtagtc tttattttgg ccactactga attgcacaag
     1381 attcctgcta ctattctatc ccgtgtgcaa cgttttgagt ttaaatcaat taagacacag
     1441 gatattaagg aacatattca ctatatctta gaaaaagaaa atatcagttc tgaaccagag
     1501 gctgtggaaa tcattgccag acgggcggaa ggtggaatgc gggacgcctt gtctattttg
     1561 gatcaagccc tgagtttgac acagggaaat gagctgacga ctgctatctc tgaagaaatt
     1621 actggcacca ttagcctatc agccttggat gattatgtgg cggccttgtc tcaacaggat
     1681 gttcccaaag ctttgtcttg cttgaatctt ctttttgaca atggtaagag catgactcgt
     1741 tttgtgaccg atcttttgca ctatttaaga gacttgttaa ttgttcaaac agggggagaa
     1801 aatactcatc atagttcagt ctttgtagaa aatttggcac ttcctcaaaa aaatctgttt
     1861 gaaatgattc gcttagcaac agtgaattta gcagatatta agtctagttt gcagcccaag
     1921 atttatgctg aaatgatgac cgtccgtttg gcggaaatca agcccgaacc agctctatca
     1981 ggagcggttg aaaatgaaat tgctacgctg agacaggaag ttgcccgtct caaacaagag
     2041 ctttctaatg caggtgcggt tcctaaacaa gttgcaccag ctcctagtcg accagctacg
     2101 ggcaaaacag tctatcgtgt cgatcgcaat aaagtgcaat ctatcttaca agaggccgtc
     2161 gaaaatcctg atttagcacg tcaaaatcta attcgtttgc agaatgcctg gggagaggta
     2221 attgaaagtc taggtgggcc ggacaaggct ctgctagttg gttctcaacc ggttgctgcc
     2281 aatgaacacc atgctattct tgcttttgag tctaacttca atgctggtca aactatgaaa
     2341 cgagacaatc tcaataccat gtttggtaat atcctcagtc aggcggcagg tttttcacct
     2401 gagattttag ctatttccat ggaggaatgg aaagaagttc gcgcagcctt ttcagccaaa
     2461 gccaaatctt ctcaaactga aaaagaagta gaagaaagcc tgattccaga aggatttgaa
     2521 tttttggctg ataaagtgaa ggtagaggaa gactaaagaa agatttcatg atacaataag
     2581 tttatgaata aacaacaatt tattattatg gcgctattta cagctgctga gacctatttt
     2641 ttcaatgaag cctggatgac tggccgctat attatggcag ccttttgggc aattttactc
     2701 tttagaaatt tccgagtcag ttatgtgatg ggtaaaattg ttgatgtcat cgatcagcat
     2761 tttaatagga aagactagcc ctcagcttcc agacaaaatc aaagcctttt aggctttttt
     2821 ttgttatact agaaaagtat atttatagaa tttttgctct atttctgggg aaatcagacg
     2881 tttttctagt aagtactgta aaagttttga aaaagaaagg aactatcatg tcagtaatag
     2941 agatcaaaga tcttcacgtt gagattgaag gaaaagaaat tttaaaaggg gttaacctga
     3001 ccctgaaaac aggagaaatt gccgctatca tgggaccaaa tggtacaggt aaatcgactc
     3061 tttctgccgc tatcatggga aatccaaact atgaagtaac taaaggtgaa gttttgtttg
     3121 atggcgtaaa catccttgag ttggaagtgg atgagcgtgc gcgtatggga cttttccttg
     3181 ctatgcaata cccatcagaa atccctggaa ttaccaatgc tgagtttctt cgtgccgcta
     3241 tgaatgcggg taaagaagat gatgagaaga tttcagttcg tgagtttatt actaagctag
     3301 atgaaaaaat ggaattgctc aacatgaaag aagaaatggc agagcgttac ctcaacgaag
     3361 gcttctctgg tggtgagaaa aaacgcaatg aaattcttca acttttgatg ttggagccaa
     3421 catttgctct tttggacgag attgactcag gtcttgatat tgacgctctt aaagttgtgt
     3481 ctaaaggtgt caatgccatg cgtggtgaag gttttggtgc tatgatcatc actcactacc
     3541 aacgtctttt gaactatatc acacctgatg tggtacacgt gatgatggaa ggtcgtgttg
     3601 tcctttctgg tggtccagaa ttggctgcgc gtttggaacg tgaaggatac gcaaaactag
     3661 ctgaagaact tggctacgac tacaaggaag aattgtaatt ccctcgtatc ttttaggaga
     3721 agtaaatgac tagagaaaat attaaacttt tttcagaaat gcacgctgaa ccaagctggt
     3781 tggctgatct ccgtcaaaaa gcttttgaca agattgagac tttggaatta ccagttattg
     3841 agcgtgtcaa attccaccgt tggaatctgg gtgatggaac gattacagaa aatgagccat
     3901 cagcaaatgt tccagatttc acagctttag atcatcactt gaagttggtg caagtaggaa
     3961 ctcaaactgt tttcgaacaa actccagttg agttagctga acagggtgtt gtcttcacag
     4021 actttcactc agctttagaa gaaattccag agctgatcga agaattcttc atgtcatctg
     4081 ttaagtatga tgatgacaag ttggcggctt accacacagc ttactttaac agtggtgctg
     4141 tactctatat tccagataac gtagaaatca cagagccaat tgaaggaatt ttctaccaag
     4201 atagcgatag caatgtgccg tttaacaagc atattatgat tatcgctggt aaaaattcta
     4261 agattagtta tctggagcgt ttagagtcac gcggtgaagg aagtgacaaa gtaactgcca
     4321 atatcacagt ggaagtgatt gcacgttctg gtgcgcaagt caagtttgct gctatcgacc
     4381 gtctaggtga aaacgtcact gcctacatta gccgtcgtgg taaattaggc aacgatgcaa
     4441 gtattgactg ggctatcggt gtcatgaacg aaggaaatgt cgttgctgat tttgatagtg
     4501 acttgattgg taatggtagc catgctgacc tcaaggttgt agctctttca agtggtcgtc
     4561 aggtacaagg gattgatact cgtgtaacta actatggctg caactctatc ggaaatatcc
     4621 tacaacatgg ggttatcctt gaaaaagcaa ctttgacttt caatggtatc ggccacatca
     4681 tcaaggatgc taagggagca gatgcgcaac aagagagccg tgttctcatg ctttcagacc
     4741 aagcgcgttc agatgctaac ccaattcttt tgattgatga aaatgatgtc actgcaggac
     4801 acgcagcgtc tatcggacaa gttgatccag aagacatgta ttacctcatg agtcgtggat
     4861 tggataaggc aactgcagag cgtttggttg ttcgtggttt ccttggatct gttatcgtgg
     4921 agattccagt caaggaagtt cgtgatgaaa tgattgcaac tatcgaagag aaattgtcaa
     4981 aacgctaagg ggaagcctat gttagatgta gaagcgattc gcaaggattt tccaatttta
     5041 gatcagattg tcaatgatga acctctggtc tatctggaca atgctgcgac gacacaaaaa
     5101 ccactagtag ttctgaaagc tattaacagt tactatgagc aggacaatgc caatgttcac
     5161 cgtggtgtcc ataccttagc ggaacgagcg acagcttctt atgaagctgc tcgtgaaacc
     5221 attcgtaagt ttattaatgc aggctctaca aaggaagttc tctttaccag aggaacgaca
     5281 accagcctta actgggtggc acgctttgct gaggaaattc tcgctgaggg agaccgggtc
     5341 ttgatttcag taatggaaca ccattctaat atcattccat ggcaggaagc ttgtcgaaag
     5401 actggagcag agcttgtcta tgtctatctt aaagacggtg ccttggatat ggaggatttg
     5461 cgagctaaat tgactgataa ggttaaattt gtttccctag ctcatgcctc caatgttctt
     5521 ggtgtggtca atccgatcaa ggaaatcact caattagccc accaagttgg ggcaattatg
     5581 gtagtggatg gtgctcaatc tacacctcat atgaagattg atgtccagga cttggatctg
     5641 gactttttcg ccttttcggg tcacaagatg gctggtccga ctggtatcgg tgtcctttac
     5701 ggcaaagaaa agtatcttga gcaaatgtct ccagtagaat ttggcggcga gatgattgat
     5761 tttgtctacg agcaatttgc tagttggaag gaattgcctt ggaaatttga ggctggaacg
     5821 ccaaatatgg caggagctat tggacttgcg actgcagttg attatctgga aaagattggt
     5881 atggatgccg ttgaagctca tgaacaggaa ttgattgcgt acgtctatcc aaaactgcag
     5941 gcaattgagg gattgaccat ttacggttct caggatttgg ctcaacgttc gggtgttatt
     6001 gcctttaacc taggtgatct ccatcctcac gatcttgcga cggctctgga ttatgaagga
     6061 gtggctgttc gtgctggtca ccattgtgcg caacccttgc ttcagtattt ggaagtccca
     6121 gcaacagctc gtgcaagttt ttatatctac aataccaagg cagattgcga caaactagtc
     6181 gatgccctac aaaagacaaa ggagtttttc aatggcactt tctaaactag atagccttta
     6241 tatggcagtg gtagcagacc attcgaaaaa tccacatcac caagggaagt tagaagatgc
     6301 tgagcaaacc agtctcaaca atccgacttg tggggatgtc atcaacctct ctgtcaagtt
     6361 tgatgcagag gaccgtttgg aagatattgc ttttctaaat tcaggatgca cgatttcaac
     6421 tgcttctgct agtatgatga cagatgccgt tttaggaaaa accaaacaag aaattttaga
     6481 actggcgact attttttctg aaatggttca agggcaaaaa gatgagcgtc aaggccaact
     6541 tggagacgcg gcattcttgt caggtgttgc caaattccct caaagaatca agtgtgcaac
     6601 cctagcttgg aatgccctta agaaaacaat tgaaaatcaa gaaaaacagt aagacaagtt
     6661 tcttttgtct tatgaattat tagaaatgaa gaaagaaagg atactatggc tgaagaaaga
     6721 gtagaaccaa aaccaattga ccttggtgaa tataaatttg gtttccatga cgatgtagag
     6781 cctgtcttat cgacaggaaa aggactcaac gaaggtgtta ttcgtgaatt atctgctgct
     6841 aagggtgagc ctgagtggat gttggagttc cgtttgaagt cttatgaaac cttcaaaaaa
     6901 atgcccatgc aaacttgggg agcagacttg tcagagattg actttgatga cttaatctac
     6961 taccaaaaac catctgacaa accagcccgt tcttgggatg atgtacctga aaagattaaa
     7021 gaaacctttg aacgtatcgg gattccagaa gctgaacgtg cttatttagc aggggcttct
     7081 gcccagtacg agtcagaagt ggtttaccac aacatgaagg aagagttcca aaaattaggt
     7141 attatcttta cagatacaga ttccgcactc aaggaatacc cagacttatt taaacaatac
     7201 tttgcgaagt tggtaccgcc gacagataac aagttggcag ccctcaactc agcagtatgg
     7261 tcgggtggaa cttttatcta cgtgccaaaa ggtgtcaagg tagatattcc acttcaaact
     7321 tatttccgta tcaataacga aaatataggt cagttcgaac gtaccttgat tatcgttgat
     7381 gagggagcaa gcgtccacta cgtagaagga tgtacagcac caacatattc aagcaatagc
     7441 ttacacgctg ccattgtaga aatttttgct ttggacggag cttatatgcg ttatacaact
     7501 atccaaaact ggtctgataa cgtctataac ttggtaacaa agcgtgctaa ggctcaaaag
     7561 gatgccactg ttgagtggat tgatggaaac ttgggtgcca aaacgactat gaaatatcca
     7621 tctgtttacc ttgatggaga aggagcgcgt ggtaccatgc tctctatcgc ctttgctaat
     7681 gcagggcaac accaagacac gggtgctaag atgattcaca atgctccaca taccagctcg
     7741 tctattgtgt ctaaatccat cgctaaaggt ggaggaaagg ttgactaccg tggacaagtc
     7801 acctttaaca agaactctaa gaaatctgtt tcccacattg aatgtgatac cattatcatg
     7861 gatgacttgt cagcatcaga tactattcca tttaatgaaa ttcacaactc gcaagtggct
     7921 ttggaacacg aagccaaagt atctaagatt tcagaagagc aattgtatta tctcatgagc
     7981 cgtggattgt cagaatctga ggcaactgaa atgattgtca tgggatttgt agaacccttt
     8041 acaaaagaac ttccaatgga atacgcagtt gagctgaacc gcttgattag ctatgaaatg
     8101 gagggatcag ttggataaaa tttgatttta tactcttcga aaatctcttc aagccacgtc
     8161 agcatcgcct taccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa
     8221 cagtgttttg agcaacctgc ggctagcttc ctagtttgtt ctttgatttt gagtattaga
     8281 tttactcaaa atcaaggatt ttgaagatga acttgtatca aaaaatcgcg gtttaaaatc
     8341 gcgatttttt ataatttctc gttaacaaag cggacaaact gattccacca aacttttaag
     8401 aagaaggctt tttcaatttt cttgtctgct accatttcga aactagggcg ctctgtggtg
     8461 atgtaacctt gaccaatcaa gtccttgtct tcataagtca aatggccaac cactgttcca
     8521 gcttcaagtg gtgctgggat tgctttggaa tcaggtgtga attgaacaga ttgggaagat
     8581 tgattcccaa tctgttcgat tagatagata tcctctggag ccactgcagt tactgtatct
     8641 tcttttccat cttgtacagg ggctttgcta tcttgatagg catcgccttg ttgaacgatt
     8701 ttgcgaagtg taaatgtaga agaaatataa tccattaggg aagatgtagc tgtaaatcga
     8761 gcgtaaggat tattgtcttg atgatctgca tttaaaacaa ctgtgatgac tctcatgcct
     8821 ttttcgacag tagtaccaac aaaagactct ccagccttat ctgttgttcc tgtttttagc
     8881 ccatcaaaac caccacggta agcaggcata ccttctaaca tgtagttggt tgaagtgatt
     8941 gtcatcccag caaaagtaga agaaggtttt ttggtgattt ctaagacttg tgggtatttt
     9001 ttgatgaggt tgcgagcaac gatagcgaca tcataagcac taagcttatt ttcctcatct
     9061 tttttagaac ctgggtaaat gttatcccct agagtttcat tgttaagacc tgtcgtattg
     9121 acaacagtgg catcctgaat tccccattcc aagagttttg cccgcatcat atcgacgaaa
     9181 tctttttctg agccagcaat tttctcagct agggcaatag cggcgctgtt ggcactagat
     9241 accagagttg cttcaagcaa ctcttcgaca gtataattac gggcctccat aggaatatta
     9301 ctggcttcag aatttgtcgt caattgataa ggataatcag aaatatctac aggagtggag
     9361 agggtaatac ttccgttttc caaagcttca tagaccagat aaacagtaat caattttgtt
     9421 atggaagcaa tttcgacagg ttgcgttgca tccttctcat agagaatttt accagtattt
     9481 gcctcaacag caatcgcatg tttagcggca atggtaaaat cttgagcaac agcagtagaa
     9541 gcacccccta aaagagagac agttaacaaa gttaaaaata tttttttcat agtagtctta
     9601 ttctatcata aagaaaaaaa atattcttgc tttaataatt catctgttaa gctttttgaa
     9661 aatatggtaa aataaagtga gggaggtaac tcatgtttcg tagaaataaa ttattttttt
     9721 ggaccacaga aattttactc ttaaccatca tcttttacct atggagacag atggggtctt
     9781 tgattaaccc ttttgttagc gtgcttaata caattatgat tccattttta ttaggggtct
     9841 ttctttatta tttgacaaac cctattgtta ctttcttaaa taaagtctgt aaactcaatc
     9901 gtttgcttgg tattttaatt accttgtgta ctttggtctg gggaatggtc ataggtgttg
     9961 tctatctctt acctattttg attaatcagt tatctagttt gattatatct agtcaaacta
    10021 tttatagtcg agtacaagac ttaatcatag acttatctaa ttatcctgcg ctccagaatt
    10081 tggatgtaga agctacaatt cagcagttaa acttatccta tgttgatatt cttcaaaata
    10141 tcctaaatag cgtatcaaat agtgtgggga gcgtcttgtc agctcttatc agtactgttt
    10201 tgattttgat tatgactcca gtttttttgg tttatttctt attagatgga cataaattct
    10261 tgcccatgct tgaaagaacg attctaaaga gggatcgctt gcatattgca ggcttattaa
    10321 agaatttaaa tgcgacgatt gctcgctata ttagtggagt ttcgattgac gcaatcatta
    10381 taggttgttt agcttatatt ggctatagta ttattggttt aaaatatgct ttagtttttg
    10441 ccattttttc tggtgtagcc aatttaattc cttatgtggg gccaagtatt ggtttgattc
    10501 ctatgatcat cgcaaatata ttcactgatc cccatagact gctgattgca gtgatttata
    10561 tgcttgttgt tcagcaggta gatggcaata tcttatatcc tcgaatcgta ggaagtgtta
    10621 tgaaggttca tccaatcacg attttagttt tacttttgtt gtcaagcaat atttatggtg
    10681 tagttggaat gattgtcgca gtgccaacct attctatctt gaaagaaatt tctaagttct
    10741 tatcccgttt gtatgaaaat cataaaataa tgaaagaacg agaaagagaa ttagctaagt
    10801 aaaagtcagg agaaccctga tttttcttta ctggaagtgg cctttagatt agaagactga
    10861 aaataagtta aagtcttaaa ctaattttca cagctaagaa tagtagaagt taatctgata
    10921 aaaatcgaaa aaaccagtgg aattctgtgt cagggtaagt tccactggtt ttcatagtct
    10981 attaaagttc gaatgaaacc tatttatagt agattgaaac tagaatagta cacctctaat
    11041 tctaaaacat tgttagaaat cgatttgact gtcctgatct attcgtccta ttcttatttc
    11101 attttactat attttggtgc aataagtgaa aagtagtccg aataatataa ggattgattt
    11161 tatagttttt aaactcaaat gaattaaaat aaagagagta cgaaaattct catctgaaag
    11221 tattttagaa taattctctt cgtgaatttc ttcaaaacag atagcttcat cttaggtatg
    11281 tgttaattgg atttcgtaag ctctatttac aatcgtaaag ttatgcactg agaaagttgt
    11341 agttagtctt ccagtttgct aaatttctcg aatagtatct tttttaggta tgtgatttct
    11401 ttttgcattt ttgagttaga taaggtataa tggttttatt gtcttttggg gtcgttacgg
    11461 attcgacagg cattatgagg catattttgc gactcgtgtg gcgacgtaaa cgctcagtta
    11521 aatataactg caaaaaataa cacttcttac gctctagctg cctaaaaacc agcaggcgtg
    11581 acccgatttg gattgctcgt gttcaatgac aggtcttatt attagcgaga tacgattaag
    11641 ccttgtctag cggcttgata agagattgat agactcgcag tttctagact tgagttatgt
    11701 gtcgaggggc tgttaaaata atacataacc tatggttgta gacaaatatg ttggcaggtg
    11761 tttggacgtg ggttcgactc ccaccggctc cattattcct ttgcattctt ttgcattcct
    11821 tggtaaaacg ttgttaaatc aacgtttttt atttttatct ttggtattcc tttgcattct
    11881 tttgctaaaa agggagtcac aaacagaccc tattttaaaa aaggatacaa catttgttgc
    11941 atcctaaaaa taatcttttt tcgacggaag acatgggatt cgaacccacg cacgctatta
    12001 cacgcctacc gcgtttccaa cacggcctct taagcctctt gagtaatctt ccaatactta
    12061 ctcaaatagt ctaccataaa ggctcttatc ttgcaataaa aattctagaa ataagaaaaa
    12121 tgatagattt tgaaagaaaa tgataaaaaa tgcttgactt cgaaataaag tatggtagaa
    12181 tgaatagtgt aaacgataac aggaggtgat tcagtgttaa aaacagaacg taaacaactg
    12241 attctagagg agttaaatca acatcatgta gtttctctag aaaaattagt tagtttgcta
    12301 gaaacgtcag aatcaacggt tcgaagagac ttggatgagt tggaagcgga aaacaagctt
    12361 cgtcgtgtgc atggtggagc agaactcccc cactccttac aggaagaaga aaccattcaa
    12421 gaaaaatctg tcaaaaacct tcaagaaaag aagttgctgg ctcagaaagc agcctctctc
    12481 attaaagaaa aagatgtcat ctttatcgat gctggaacaa caactgcttt tttgattcat
    12541 gaattggtca ataagaatgt tacagttgtg accaactcca ttcaccatgc cgctcagttg
    12601 gttgaaaagc agattccaac tgtcatggtt ggaggaaacg tcaagacggc gacagatgct
    12661 agtatcgggg gcgttgctct taaccagatt aaccaattgc actttgaccg tgcctttatc
    12721 ggaatgaatg gtgttgacga tggctattat acgactcctg atatggagga gggagctgtg
    12781 aaaagagcta ttttggagaa tgccaagcag acctacgtct tggtggattc gtcaaaaatt
    12841 ggacaaactt gctttgccaa ggtagcacca ctcaaacgcg ctatcgttat cactagtcaa
    12901 gggcatgagc tcttgcaggt tattaaggag aaaacggagg taatagaagt atgatttata
    12961 cagtcacact caatccatcc attgactata tcgttcgttt ggaccaagtc aaagttggta
    13021 gtgtaaatcg tatggacagt gatgataagt ttgctggtgg gaaaggaatc aatgtcagcc
    13081 gtgtcttgaa acgtttgaat ataccaaata cagcgacggg atttatcggt ggctttactg
    13141 gtaaatttat cacagatact ttagcagagg aagaaatcga gacacgtttt gtccaggtgg
    13201 cagaagatac tcgtatcaat gttaaaatca aagcagacca agaaacagaa atcaacggaa
    13261 cgggtccaac tgttgaatcg gttcagctag aagaattgaa agctatttta tctagtctga
    13321 cagcagaaga tacagttgtc tttgcaggtt caagtgctaa aaatctaggc aatgttatct
    13381 ataaggattt gatttccttg acgcgccaga ctggtgcgca agtggtctgt gactttgaag
    13441 gacagacctt aattgatagt ttggactacc agcctcttct tgtaaaacca aacaatcatg
    13501 aacttggagc gatttttggg gttaaactcg aaagtttaga tgaaattgag aaatacgctc
    13561 gtgagttact ggctaagggt gctcaaaatg ttattatctc tatggctggt gatggtgccc
    13621 ttcttgtcac atctgatgga gcttacttcg ctaaaccaat caagggaaca gtcaaaaatt
    13681 cagttggagc tggtgattct atggttgctg gattcacagg tgaatttgtc aaatcaaaag
    13741 acgcagtaga agccttcaaa tggggagtgg cttgcggaac ggcaactacc ttctcagatg
    13801 acttggcaac ggcggaattt attaaagaaa catatggaaa agttgaggta gaaaaacgat
    13861 gaaaattcaa gacctattga gaaaagatgt catgttgcta gatttgcagg caactgaaaa
    13921 aacagctgtc atcgacgaga tgattaaaaa tttgacagac cacggttatg taacagattt
    13981 tgaaacattt aaagaaggca ttttggcgcg tgaagctttg acttctactg gtttgggtga
    14041 tggaatcgca atgcctcaca gcaaaaacgc tgctgtcaaa gaagcgacag ttctatttgc
    14101 taagtcaaat aagggtgttg actacgagag cttggatgga caagcaactg acctcttctt
    14161 catgattgca gctccagaag gtgccaatga tactcacttg gcagccttgg cagaattgtc
    14221 tcaatacttg atgaaagacg gttttgcaga caaacttcgt caagcaacat ctgcagacca
    14281 agttatcgaa ctttttgacc aagcttcaga aaaaactgag gaacttgttc aagcacctgc
    14341 taatgactct ggtgacttta tcgtagctgt tacagcttgt acaacaggta ttgcccacac
    14401 ttacatggcc caagaagccc ttcaaaaagt agctgctgaa atgggggttg gtatcaaggt
    14461 cgaaaccaac ggtgctagcg gtgttggaaa tcaactaact gcagaagata tccgtaaggc
    14521 taaagctatt atcattgcag cagacaaggc cgttgaaatg gatcgatttg atggaaaacc
    14581 attgatcaat cgtccagttg ctgacggtat ccgtaagaca gaagagctaa ttaacttggc
    14641 tctttcagga gatactgaag tctaccgtgc cgctaatggt gccaaagctg caacagcctc
    14701 taacgaaaaa caaagccttg gtggtgcctt gtacaaacac ttgatgagtg gtgtatctca
    14761 aatgttacca ttcgttatcg gtggtggtat catgattgcc cttgccttct tgattgacgg
    14821 tgctttgggt gttccaaatg aaaaccttgg caatcttggt tcttaccatg agttagcttc
    14881 tatgttcatg aaaattggtg gagctgcctt tggtttgatg cttccagtct ttgcgggtta
    14941 tgttgcctac tctattgctg aaaaaccggg tttggtagca ggtttcgtgg ctggtgctat
    15001 tgccaaagaa ggttttgcct ttggtaaaat tccttatgcc gcaggtggtg aagcaacttc
    15061 aactcttgca ggtgtctcat ctggtttcct aggtgccctt gttggtggat ttatcgcagg
    15121 tgccttggtt cttgccatca agaaatacgt taaagttcct cgttcactcg aaggtgctaa
    15181 atcaatcctt ctattgccac ttcttggaac aatcttgaca ggatttgtta tgctagctgt
    15241 gaatatccca atggctgcaa tcaacactgc tatgaatgac ttcctaggcg gtcttggagg
    15301 aggttcagct gtccttcttg gtatcgtcct tggtggaatg atggctgttg acatgggtgg
    15361 accagttaat aaagcagctt atgtctttgg tacaggtacg cttgcagcaa ctgtttcttc
    15421 aggtggttct gtagccatgg cagcagttat ggctggagga atggtgccac cacttgcaat
    15481 ctttgtcgca actcttcttt tcaaagataa atttactaag gaagaacgta actctggttt
    15541 gacaaacatc atcatgggct tgtcatttat cactgaggga gcgattccat ttggtgccgc
    15601 tgacccagct cgtgcgattc caagcttcat ccttggttca gcagtagcag gtggactcgt
    15661 tggtcttact ggtatcaaac tcatggcgcc acacggagga atcttcgtta tcgcccttac
    15721 ttcaaatgct ctcctttacc tcgtttctgt cttggtagga gcaatcgtaa gtggtgtggt
    15781 ttatggttac ctacgcaaac cacaagcata aaaaatagaa aaatgaaaag attggaccgt
    15841 ttggtgcagt ctttttctct tcccgaaatg cctgtgaaat atggtataat agaagaatgg
    15901 caaacaagaa tacaagtaca acaagacgga gaccgtctaa agcagaactg gaaagaaaag
    15961 aagcgattca acgaatgttg atttcattag gaattgcgat tttattgatt ttcgcagtct
    16021 tcaaattagg ggctgcaggt ataacccttt ataatttaat tcgcttgcta gtgggtagcc
    16081 tagcttatct ggcgatattc ggcctattaa tctatctctt ctttttcaag tggatacgaa
    16141 aacaggaagg actcttatct ggctttttca ccatatttgc tggcttactc ttgatttttg
    16201 aagcctactt ggtttggaaa tatggtttgg acaagtccgt tctaaaaggg accatggctc
    16261 aggttgtgac agatctgact ggttttcgaa cgactagctt tgctggaggg ggcttgatag
    16321 gggtcgctct ttatattcca acagcctttc tcttttcaaa tatcggaact tactttattg
    16381 gttctatctt gattttagtg ggttctctcc tagtcagccc ttggtctgtt tacgatattg
    16441 ctgaattttt cagtagaggc tttgccaaat ggtgggaagg gcacgagcgt cgaaaagagg
    16501 aacgctttgt caaacaagaa gaaaaagctc gccaaaaggc tgagaaagag gctagattag
    16561 aacaagaaga gactgaaaaa gccttactcg atttgcctcc tgttgatatg gaaacgggtg
    16621 aaattctgac agaggaagct gttcaaaatc ttccacctat tccagaagaa aagtgggtgg
    16681 aaccagaaat catcctgcct caagctgaac ttaaattccc tgaacaggaa gatgactcag
    16741 atgacgaaga tgttcaggtc gatttttcag ccaaagaagc ccttgaatac aaacttccaa
    16801 gcttacaact ctttgcacca gataaaccaa aagatcagtc taaagagaag gaaattgtca
    16861 gagaaaatat caaaatctta gaagcaacct ttgctagctt tggtattaag gtaacagttg
    16921 aacgggccga aattgggcca tcagtgacca agtatgaagt caagccggct gttggtgtaa
    16981 gggtcaaccg catttccaat ctatcagatg acctcgctct agccttggct gccaaggatg
    17041 tccgaattga agcaccaatc cctgggaaat ctctaatcgg aattgaagtg cccaactccg
    17101 atattgccac tgtatctttc cgagaactat gggaacaatc gcaaacgaaa gcagaaaatt
    17161 tcttggaaat tcctttaggg aaggctgtta atggaaccgc aagagctttt gacctttcta
    17221 aaatgcccca cttgctagtt gcaggttcaa cgggttcagg gaagtcagta gcagttaacg
    17281 gcattattgc tagcattctc atgaaggcga gaccagatca agttaaattt atgatggtcg
    17341 atcccaagat ggttgagtta tctgtttaca atgatattcc ccacctcttg attccagtcg
    17401 tgaccaatcc acgcaaagcc agcaaggctc tgcaaaaggt tgtggatgaa atggaaaacc
    17461 gttatgaact ctttgccaag gtgggagttc ggaatattgc aggttttaat gccaaggtag
    17521 aagagttcaa ttcccagtct gagtacaagc aaattccgct accattcatt gtcgtgattg
    17581 tggatgagtt ggctgacctc atgatggtgg ccagcaagga agtggaagat gctatcatcc
    17641 gtcttgggca gaaggcgcgt gctgcaggta tccacatgat tcttgcaact cagcgcccat
    17701 ctgttgatgt catctctggt ttgattaagg ccaatgttcc atctcgtgta gcatttgcgg
    17761 tttcatcagg aacagactcc cgtacgattt tggatgaaaa tggagcagaa aaacttcttg
    17821 gtcgaggaga catgctcttt aaaccgattg atgaaaatca tccagttcgt ctccaaggct
    17881 cctttatctc ggatgacgat gttgagcgca ttgtgaactt catcaagact caggcagatg
    17941 cagactacga tgagagtttt gatccaggtg aggtttctga aaatgaagga gaattttcgg
    18001 atggagatgc tggtggtgat ccgctttttg aagaagctaa gtctttggtt atcgaaacac
    18061 agaaagccag tgcatccatg attcagcgtc gtttgtcagt tggatttaac cgtgcgaccc
    18121 gtctcatgga agagcttgag atggcaggtg tcattggtcc agctgaaggt accaagccaa
    18181 gaaaagtatt gcagcaataa aaaatagctt ctttccaagt ttggaaggag gctattttag
    18241 tgattattga ttagttttat tttccgaagt tggggtattg gactgttttt cgttttcagt
    18301 agcaggttta cttggagtag gagcaggagt agaagaatcc tgagttgatg ttttctgctc
    18361 ttcttttttc tcttccttga cgctggattt tggcgtttct tcttgttgtg ttttttcttg
    18421 agaagtctta ttttccttat tgggactagt attttcctga ggggattcct tttgaatttc
    18481 tttgacaatt gttgtcgtct ggcttgttgt aggttccttt ttagtatttt tgttattatc
    18541 caaggcgttc ataatcgtga tactagcggt aatcaagcca aggatactag cgatagtcgc
    18601 aacggttttt tgaaagactg taaagccttt tttgatgtgt tctgtttttg gttttgaagt
    18661 tctacgataa ttagacatac attctctcct ttaattaaaa tttattatac ctcatttctt
    18721 taaaaaaatc ttaaaaaaag aggagatttt tctacacgaa cttcagtaat tagttgaaat
    18781 aaaatatgac ttatgatata acaaaataaa gaaagcgatt tcaaaaaagg agggcgttat
    18841 atgttcgaaa ttagaaattt gagtctctct tttgcaggca ggcggttgct agagccaaca
    18901 gatttgatat ttgaaagggg aaaagtatat acaatatatg ggaagtcagg cgtaggaaag
    18961 tcttctttac tgaataaaat tggtttgctc tctgctacgg atcctagtgt ttcttatttc
    19021 ttcgatggaa aagagattga tatcgaaaat aagaaatcag tctctgtctt tatagctgaa
    19081 gaagttgcct ttgtatttca ggggcgaaat ctaataaatg atttgaccgt atttgaaaat
    19141 ttaagactag ctttaaactt ttatgacttg agtccagatg aaatagaaag caaaattgat
    19201 acagtattgg cggatttaca gatttcttct ttaaagcatg cttatccaga agatttatcc
    19261 ggtggtgaag aacaacgagt ggcaatcgca agagccttag ttacaggaaa gactctcatc
    19321 ttagctgatg aaccaacaag ttctttggat aaagaaaata gagaaaaaat ctccgccttg
    19381 ttaattgatt tagctcacaa atatcataaa attgtattga ttgtttcgca tgatgaggcg
    19441 atgattgcaa taggagatgt tcagcttcat tttaaagacc ataaattagt tgggaattgt
    19501 cttattttga attctgatga agggataaag gattctaaga agtggtcctc ctgtttgtcg
    19561 tcttctcata cgaagctatc cgttttgaaa catagaaggc cttttttacc tagattatta
    19621 gcgtttttta tctctcttgt agttgctata gcagtaacct ctattaactt tcagtcctta
    19681 tttgcagata agtatcacca actggtgaac aactcactcg aaaatggctt cttggtgatt
    19741 aatgattcgc ttcatttaca aactacaaaa gtgttggatg attttctcag ttttgataag
    19801 gaggaaatca cctcaattag cacaagtcag aatattcaaa ccgtcaatcc ttatatagag
    19861 tttctctctt tgggtatgac gtttgataat tcaaaagact attcacaact tcaaaagaac
    19921 tttcagccaa ctttgactat tgatggtcag accagaagct tgacaagaaa tttttcaatt
    19981 caacccttgt atcagacaaa tacaacacag aggcagatag agtattttga taggagcaat
    20041 gaaaaaggga tttatctatc tgagcaattc atttcagatg aaaaattacc aaatatagtt
    20101 tcgggaacta ccgtgacact gactttttat attccaattt ctttatatga atcaagtata
    20161 gagaaagagg ggaatatatt gaaaggagat ggcggtttat ttgtcaaagt ggataaaaca
    20221 tatcctgttt tagggattgt taaaaaaagt tatccgtttg aatattcccc ttatgggaac
    20281 accctattta tgaatattgc tgaaatggaa gaattgcaaa atgaagcaat tcaacagcat
    20341 cccatgacga agatggcttt agatggtttt cctttgaaat catggatgcc gagtgcgatt
    20401 catgtgttac taaaggatag cggtgctatt cctgaagaat tgagtagaat aagagcaatc
    20461 tcttcacaaa ttactatttt atcatcatat gaaaactacg aagaatttaa taaaggactc
    20521 acctatatca ggcaattttt aatgttgcta tccctagtct tactcatcct tgtcatcgca
    20581 gtattgtcct ttgttttctt tttgctcaat cgtcctcgac gctttgaagt agggatttta
    20641 aaatctttgg gatacagtac tcaaaatatt gtttggcttt tcttaaaaga attaattggt
    20701 tatggtaaaa caatttcgat attagcaagt tgtttactcg tcattctttc cattttagca
    20761 atgcaagtgc ttaaattgga aatttcagat gtttttaaat tctatctaac ttccgttttc
    20821 accttaattg gattatcagt ctcagtactg ataataagtg gcttactacc tatatacaca
    20881 acttgtaggc aaacagttgt cgatactatc cgaaagaatg gatgaggtga tatcatgaaa
    20941 cataagataa tgaaaaaaat aatagtggta gtgtttgcta tcccatggtt aacattttta
    21001 agtcaagtac atgcagatta tgtaagtaag tctagttctt tagacggtta tagcttggta
    21061 ggcttgaatg ttcttaatgt gacttttaat gcttctggct attctgatac ttatagtggc
    21121 agtgtgtcaa atatgtattt cactgactgg gcttggtttc ctaatacgat aagtaatcgt
    21181 tccacttgga aaagttcgat tccatatggt caacgcgcaa atggtacagt ccatataggt
    21241 gtaggagtaa attcgccttg gggagcggtt aatctctggg gcggacaaaa ttacttttct
    21301 ttagattttt aacagaaata atcaaagtta gatagaatga ataagaatgc tcttgatgat
    21361 ggtatcaaga gtattttatg ttattcagat taatgcaaac attgcccttt cttgtcgcag
    21421 gctccgtttc atgatacaat agaaggagtg attttagaaa gcgtgagaaa catgatttac
    21481 tttgataatt cggcgacgac caggccctat ccagaagccc ttgaaaccta tatgcaggtg
    21541 gcttcaaaaa ttttaggaaa tccatctagt ctccatcgtt tgggagacca ggcaacacga
    21601 attttagatg cttcccgtca acagattgca gatttaatcg gtaagaaaag tgatgaaatc
    21661 ttctttacat ctggtgggac agaaggggat aactggatca tcaagggagt agcatttgaa
    21721 aaagcccagt ttggcaagca catcatcgta tcagccattg aacatccagc agttaaggaa
    21781 tcagccctct ggttgaaagc tcaaggtttt gaagtggatt ttgctccagt tgataacaaa
    21841 ggatttgtgg atgttgaggt gctagaagat ttgataagac ctgatacgac cctcgtttcc
    21901 atcatggcag ttaacaatga aattggctct gttcagccca ttgaggctat ttcaaaacta
    21961 ttggcagaca agccaactat ttccttccac gttgatgcgg ttcaggcgct tgccaagatt
    22021 ccgactgaaa agtatctgac agaacgagtg gatttcgcga ctttctctgg tcacaagttc
    22081 cacggaatcc gtggtgttgg ttttatctat atcaagtctg gcaagaagat tacgcctctt
    22141 ttaacaggtg gtggtcagga acgtgattac cgttcgacaa ctgaaaatgt ggcaggaatt
    22201 gcagcgaccg ctaaggctct ccgtttatct atggaaaagc tagatatctt taggagcaag
    22261 actgggcaga tgaaggcagt gattcgtcaa gcacttctgg actatccgga tatatttgtc
    22321 ttttcagatg aggaagactt cgcccctcat attctgactt ttggaatcaa gggtgttcgt
    22381 ggtgaggtca ttgttcacgc ctttgaagac tatgatattt tcatctcaac gacctcggct
    22441 tgttcgtcca aggctgggaa accagccgga accctgattg ctatgggagt ggacaaggat
    22501 aaggctcagt cagctgtgcg tcttagtcta gaccttgaaa atgatatgag tcaggtcgag
    22561 cagttcttga ccaagctaaa attaatttac aatcaaacta gaaaagtaag ataggagcat
    22621 tcatgcagta ttcagaaatt atgattcgct acggtgagct gtcaaccaag ggcaaaaatc
    22681 gtatgcgttt catcaataaa cttcgcaata atatttcaga cgttttgtct atctatcccc
    22741 aagttaaggt aacagcagat cgcgaccgtg cccacgctta cctcaatgga gcagattaca
    22801 cagcagtagc agaatcgctc aaacaagtat ttggaattca aaacttttcc cctgtttata
    22861 aggttgaaaa atctgtagaa gttctgaagt ctgctgtcca agagattatg caggacatct
    22921 acaaggaagg catgaccttt aaaatctcta gcaagcgtag cgaccacacc tttgaattgg
    22981 acagtcgtga actcaaccaa acgcttggag gggctgtatt cgaagccatt ccaaacgtac
    23041 aagctcaaat gaaaagtcct gacatcaatc ttcaggtgga gatacgtgaa gaagcagcct
    23101 atctttctta tgaaaccgtt cgaggggcag gtggattacc agtgggaact tctggtaagg
    23161 gcatgctcat gttgtcaggg ggaatcgatt cccctgtagc tggctatcta gcgcttaaac
    23221 gagggggaga tatagaggca gttcactttg ccagcccacc ttacacgagt cctggtgctc
    23281 ttaaaaaagc ccaagatttg acccgtaaat taaccaaatt tgggggaaat atccagttta
    23341 tcgaagttcc ttttacagag attcaagagg aaatcaaagc caaagcgcca gaagcctacc
    23401 ttatgacctt gacgcgtcgt tttatgatgc gtattactga ccgtattcgt gaggtacgaa
    23461 atggtttagt tatcatcaat ggggaaagtc taggtcaagt agccagccaa acccttgaaa
    23521 gtatgaaggc tatcaatgct gttaccaaca ctcccatcat tcgtcctgtg gttaccatgg
    23581 acaagttgga aatcattgac atcgcccagg aaatcgatac ctttgacatt tcaatccaac
    23641 cgtttgaaga ctgttgtacc atttttgcac cagatcgtcc aaaaacaaat cctaaaatta
    23701 agaatgcgga gcagtacgaa gcgcgtatgg atgttgaagg cttggttgag cgagcagtgg
    23761 ctggaatcat gattactgaa atcacacctc aagccgaaaa agatgaagtt gatgacttga
    23821 ttgacaatct gctctaattc agaaaatcca aaagaatagc gaaaatcagt aaaaaaagtt
    23881 agttttttct ctaaaaacag gtaaaaaact aacttttttt atttt
//
LOCUS       DBERDS010000028        22511 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.028, whole genome shotgun sequence.
ACCESSION   DBERDS010000028 DBERDS010000000
VERSION     DBERDS010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.028"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(74..424)
                     /gene="rbfA"
                     /locus_tag="ACL73E_001283"
     CDS             complement(74..424)
                     /gene="rbfA"
                     /locus_tag="ACL73E_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGS0801249.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(675..3440)
                     /gene="infB"
                     /locus_tag="ACL73E_001284"
     CDS             complement(675..3440)
                     /gene="infB"
                     /locus_tag="ACL73E_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGS0801250.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAEPVAPKTEKVAAKPQSRNFK
                     AEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQ
                     QGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKE
                     ALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRD
                     DYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFH
                     ELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYG
                     IEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRV
                     ATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDG
                     VMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVE
                     ISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGT
                     LNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEK
                     SARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSA
                     SLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVE
                     IRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKV
                     ARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAY
                     VMEEIKR"
     gene            complement(3457..3756)
                     /locus_tag="ACL73E_001285"
     CDS             complement(3457..3756)
                     /locus_tag="ACL73E_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGS0801251.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIEDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(3749..4042)
                     /locus_tag="ACL73E_001286"
     CDS             complement(3749..4042)
                     /locus_tag="ACL73E_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGS0801252.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(4064..5200)
                     /gene="nusA"
                     /locus_tag="ACL73E_001287"
     CDS             complement(4064..5200)
                     /gene="nusA"
                     /locus_tag="ACL73E_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGS0801253.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(5244..5723)
                     /gene="rimP"
                     /locus_tag="ACL73E_001288"
     CDS             complement(5244..5723)
                     /gene="rimP"
                     /locus_tag="ACL73E_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGS0801254.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(5849..6484)
                     /gene="trmB"
                     /locus_tag="ACL73E_001289"
     CDS             complement(5849..6484)
                     /gene="trmB"
                     /locus_tag="ACL73E_001289"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGS0801255.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(6481..7275)
                     /gene="ccrZ"
                     /locus_tag="ACL73E_001290"
     CDS             complement(6481..7275)
                     /gene="ccrZ"
                     /locus_tag="ACL73E_001290"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGS0801256.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(7437..8048)
                     /locus_tag="ACL73E_001291"
     CDS             complement(7437..8048)
                     /locus_tag="ACL73E_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0801257.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(8199..8432)
                     /gene="blpZ"
                     /locus_tag="ACL73E_001292"
     CDS             complement(8199..8432)
                     /gene="blpZ"
                     /locus_tag="ACL73E_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGS0801258.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(8474..9163)
                     /locus_tag="ACL73E_001293"
     CDS             complement(8474..9163)
                     /locus_tag="ACL73E_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0801259.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRELLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(9215..9598)
                     /locus_tag="ACL73E_001294"
     CDS             complement(9215..9598)
                     /locus_tag="ACL73E_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGS0801260.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(10227..10546)
                     /locus_tag="ACL73E_001295"
                     /pseudo
     CDS             complement(10227..10546)
                     /locus_tag="ACL73E_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(10608..10769)
                     /locus_tag="ACL73E_001296"
     CDS             complement(10608..10769)
                     /locus_tag="ACL73E_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801261.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIVYMIAVMIYF
                     SLIKKKEKK"
     gene            complement(11066..11185)
                     /locus_tag="ACL73E_001297"
     CDS             complement(11066..11185)
                     /locus_tag="ACL73E_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGS0801262.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(11188..11418)
                     /gene="blpU"
                     /locus_tag="ACL73E_001298"
     CDS             complement(11188..11418)
                     /gene="blpU"
                     /locus_tag="ACL73E_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGS0801263.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(11487..11756)
                     /gene="blpJ"
                     /locus_tag="ACL73E_001299"
     CDS             complement(11487..11756)
                     /gene="blpJ"
                     /locus_tag="ACL73E_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGS0801264.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(12223..12420)
                     /gene="blpI"
                     /locus_tag="ACL73E_001300"
     CDS             complement(12223..12420)
                     /gene="blpI"
                     /locus_tag="ACL73E_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGS0801265.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            12710..13297
                     /locus_tag="ACL73E_001301"
     CDS             12710..13297
                     /locus_tag="ACL73E_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGS0801266.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            13224..14867
                     /locus_tag="ACL73E_001302"
     CDS             13224..14867
                     /locus_tag="ACL73E_001302"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGS0801267.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDVLASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            14878..16239
                     /locus_tag="ACL73E_001303"
     CDS             14878..16239
                     /locus_tag="ACL73E_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGS0801268.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANYLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            16296..16451
                     /gene="blpC"
                     /locus_tag="ACL73E_001304"
     CDS             16296..16451
                     /gene="blpC"
                     /locus_tag="ACL73E_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGS0801269.1"
                     /translation="MDKKQNLASFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(16496..17836)
                     /locus_tag="ACL73E_001305"
     CDS             complement(16496..17836)
                     /locus_tag="ACL73E_001305"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGS0801270.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(17850..18587)
                     /locus_tag="ACL73E_001306"
     CDS             complement(17850..18587)
                     /locus_tag="ACL73E_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGS0801271.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETDLLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(18592..18930)
                     /locus_tag="ACL73E_001307"
     CDS             complement(18592..18930)
                     /locus_tag="ACL73E_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0801272.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNI
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            19206..19535
                     /locus_tag="ACL73E_001308"
     CDS             19206..19535
                     /locus_tag="ACL73E_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGS0801273.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(19703..20752)
                     /locus_tag="ACL73E_001309"
     CDS             complement(19703..20752)
                     /locus_tag="ACL73E_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801274.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(20749..21480)
                     /locus_tag="ACL73E_001310"
     CDS             complement(20749..21480)
                     /locus_tag="ACL73E_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801275.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            21548..21958
                     /locus_tag="ACL73E_001311"
     CDS             21548..21958
                     /locus_tag="ACL73E_001311"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGS0801276.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            21968..22255
                     /locus_tag="ACL73E_001312"
     CDS             21968..22255
                     /locus_tag="ACL73E_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801277.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
BASE COUNT         7042 a         4918 c         3879 g         6672 t
ORIGIN      
        1 tttaaaagaa tatttttcca tttcaaattc aacctatttt cctccaccaa aaaagagggg
       61 caacccctct tctttagttc ttatccagat tgcgtagcat ctcgtcaatc ttgtttccat
      121 actcgatgga ctcgtctttg acgaaggtca aatctgggat tttgtacaat ttcaaattgc
      181 gaccaagttc acgtttgatg gtaccagttg ctttttcaag cccgatttgg gctttttggt
      241 tatccgaagc aaggttactc aaaatggtgt aataaacctt ggcaacagac aagtcaccca
      301 gcatctgaac atctgtgatg gtcacacctt ggacacgtgg atcacggact ttcttttgca
      361 aaatctcatt gacttcacgc ttgatttcca tgcccacacg atctgtacgg aaatgatttg
      421 ccatgatatt cctttctcta ctttgaacca aaagctaggc cagcagacct agctatttta
      481 aacttcttga ttttcagttt aaattgaaac gaagttcaat ttgaagtcat ctgcttcttt
      541 cgccgtggtg aaagtgatgg aactgattta tcagtcccat cacaggggat ttttgagacc
      601 ctaggctcaa aaataagcaa tgaaaccatc ggtttgcttg cgtccctcac cacctaagaa
      661 aggagcaaaa aatcttatct cttgatttct tccatgacat acgcctcaat cacatcatcc
      721 atcttaatat cattgtagcc gtcgatcatc aatccacctt cacggccgtt tgtaacttcc
      781 ttaacgtcgt ctttatagtg tttcaagctt gcgagttcac catcatagat aacgacacca
      841 tcacggataa cacggacttt agagtcacgg gcaaccttac cgttgataac cataaatcca
      901 ccgatagttc ccactttaga caccttgaag gtttcacgga taaccgcttc accaataact
      961 ttttcttcaa attctggatc aagcatccct ttcatagctt cttccatctc ttcgataacc
     1021 ttgtagataa tgctgtgaag acggatttcc acatcgtcag cttctgcttg ttgacgagct
     1081 tgtggtgtag ggcgtacgtt gaaaccaacg ataaaggcat ttgaagcttc ggcaagggtc
     1141 acgtctgatt cgttgatagc accgaccgct gagtggacga tagtcacttt gacaccttcc
     1201 acgtcaatct tttgaagtga ggcagaaagg gcttcaacag aaccttgtac atcagccttg
     1261 atgataacat taacagattt gagttcccca gctttaaggg tatcaaagag gttttcaagg
     1321 ctaacacgtt gggtagcttg acgttgtttc atgagggcac gtttggcacg ctcttcacct
     1381 gctgcacgcg cagatttttc atcctcgtaa acggcaaagt ggtcacccgc catcggtgct
     1441 tcgttcaaac ctgtgataga gactggtgtt gatggtccag caactttaac acgacgacca
     1501 aggtcgttgg tcatagcacg gacacgaccg aaggtatttc cgacaacgat tgggtcttga
     1561 acattcaagg taccttgttg tacaagaagg gttgcgaccg caccttttcc tttatccaag
     1621 cgcgcttcga taaccgtacc gattgcacgc actgttgggt ctgccttgag ttcttggatt
     1681 tcagctacaa gaaggactgt ttccaacaat tcttcgatat tttggttgaa tttagctgag
     1741 atttcaacaa attcagaatc tccaccccaa gcggttgaca tcacaccatg ctctgccaat
     1801 tcaccgataa cgcgttctgg gttagcacct ggtttatcaa tcttgttaat ggctacgatg
     1861 attggaacgt tagctgcttt tgagtggttg atggcttcaa tagtctgagg cataaccccg
     1921 tcatctgccg ctacgaccaa gatcgtaata tcggtaacag aagcaccacg cgcacgcatt
     1981 gatgtaaagg ccgcgtgtcc tggtgtatca aggaaggtaa tcttcttacc attttccacg
     2041 atttggtagg caccgatatg ctgagtaata ccacctgctt cacctgtcgc aacacgtgag
     2101 ttacgaagag tatccaaaag ggttgtttta ccgtggtcaa cgtgtcccat gatagtaaca
     2161 actggtggac gctcaaccaa ttcatcttca ttgagataac catcttcgac aaagaaacgt
     2221 tcgatgtcag cattatccac ttcaaccttt tgtttggctt cgataccgta atccaccatg
     2281 aggagttcaa ttgtttcccc atccaaggat tggttttgtg tggccatgac acccatcatg
     2341 aaaagtttct taacgatttc agctggttca cgtttgatac gttttgcgat ttccgcaacg
     2401 gtcataccat ctgtatattc aaattctgtt ggcaattcat ggaatttacg ctccgtaaca
     2461 ggttttggag tctgattacg gttgttcttg ttattgcctt ttttgttctt tttgttgtta
     2521 ttccagttac tattcttttg atttctcact tgattttgac tacttcgatt cttttgttgt
     2581 tttctaggac catcttcttc atgatcataa tcgtcacgat ttttgtctgg tcgagcttgt
     2641 tttttacgac gtgtatccac tgcaggttct tttttctcag ggacgacttc aaccactgct
     2701 tgaacttgct gtgcttgttc agctaactta gccgcttctt caaagatttc ctctggttcc
     2761 ttgcgtttgt tagcttgagc caaggcttct ttagcagcct gatactgctt gaagcgttcc
     2821 tcacttgaac gagcgtactc tgcattttgc tctgctttta gggctgctgc acgggcttta
     2881 aagtcaatac gtggagccgc ttgatttgaa cgtttatcct cttgctgacg gcgctcattt
     2941 ctacgttttt gctgaccttg ctgcttctta gcttggtcat taaagcgacg attgtcgcgg
     3001 ttgctttgac cttgttttcc accattacgg ccgtcgtttt tctgacggtt tccgttttgt
     3061 tgttggtcac ggttattgcc cttattttgc ttgcgtcgct ctgcctgctc tttagcacgt
     3121 gcttcacgct cagccttgaa attacgactt tgcggtttag ccgctacttt ttctgttttc
     3181 ggagcgactg gctcagctgg tttagctggc tcagattttt cggctttctt ttctgcactt
     3241 acttttggtg ctgcaggttt tgcttctact ttcggagcag ctgcaggctt aaagctggca
     3301 gcaatttttg cagcgacagc ttcttccaca cttgatgagt ggcttttcac atccaagccc
     3361 aactcttttg cacgcgctac aacttcttta ctttcttttc caagttcttt tgcgatttcg
     3421 tacaatcttt tcttagacaa atcatgtcct cctcttctat tccataagag acctcatttt
     3481 ctttgtaaat ccagcatctg ttacagccaa aacctttctc gatttcccga ctgctatgct
     3541 taattccagt gttgaaaaca cggttacaat ttctacttga taataatgac ttttatcttc
     3601 aatcttcttg gtcagattgg gtccagcatc atgagctaga aagaccaact tggccttgcc
     3661 gtcttgaatg gccttgacca ccaattcttc acccgatatg atgcgccctg ctcgctgagc
     3721 aagccccaag agattactta tcttttgctt attcaagtcc caactctctt cttttcactt
     3781 tgtgatccac ataagcgatc aactcgtcat aaaagctttc ttccacttcc atgctaaagc
     3841 tgcggttaaa gaccttcttc tttttcgcct ctagggcttc tgcattgtct agtttgatat
     3901 aagcgccgcg gccattggcc ttgcccgtag gatcaataaa gacttgtcct tccttgttct
     3961 tgacaatgcg gagcaaatca cgcttatcaa tcacttcgtt agacacaaca gacttgcgca
     4021 aagggatttt tcttgttttc atctttccct cctctagcag cttttattct tctacagtat
     4081 cgttttctac ttccaactct actgaagcag cgtcttccat ggcttcaaat tcgctagcag
     4141 acttgatatc gatacggtaa ccagtcaagt gagccgccaa gcgcacgttt tgtccacgac
     4201 gaccaatggc aagagaaagc ttgttatctg gaacaaccac caaggcacgt ttgctgtcgt
     4261 tttcatcaaa gataacttgg tcaacctcag caggagcgat ggcattgtag ataaattcag
     4321 ctggatctgc tacccactcg ataacatcga tattttcttc gattggtacc atgcggtcat
     4381 ttttagcatc gtaacgagct gggtggaatt tgctagtaat cttcttgata ttagcaccac
     4441 cacgtccaac gattgtaccg atagcatcca cgtttggatt gtggctacga acagcaacct
     4501 tcgtacggtc acctgcttca cgagccacgc tcatgatttc aacagttcca tcataaactt
     4561 ctggaatttc ttgctccatc aaacgtttga tcatttctgg atggctacgg ctaacaaaga
     4621 cgttcacacc acgagggttg tcttcaacct tgtaaacata aacttcgata cgatcatgag
     4681 aagcaaaaac ttctccagga atttggtctt gttttgacaa ttgggcttcg atgctaccaa
     4741 ggttgacata gataaagcgg ttgtcaaagc gttctactgt accagacatg atttcttgct
     4801 catgttcttt gtaagtattg taagtgatgg cacgtgtttg cttgcgcatt ttttccatga
     4861 tggtttgttt ggcagattgg gctgctacac gaccaaactc agctggtgct tcttcaaact
     4921 tgattttgtc tccaagttca taagctgaat taatggcaag agcatctttc aagctgattt
     4981 ccaaacggct atcaaatact tcatcaacaa cttcacggac agtataaact gtaaagtcac
     5041 ctgttttttc gttgaagtca atagctacgc tgtctgactg accatagcgt ctgcgataag
     5101 cggaacgaag cgactctact actgcgtcga tgatatcttc ttttttgatt cccttgtctt
     5161 cttccaaaat gcggaaggcc tctagcattt ctttactcat gttttcttca cttttgaatc
     5221 ctcaaaagct atcctttctt tttctataat ttaactgcta aacgtgcttt tgatactaaa
     5281 ctgtatggaa tttggacggt tttcttacgc gtcttgtcca tatattccat agtcaactcg
     5341 tcctcttcga aggccaacaa ggttccttca aagacctttt gcttatcgat ggcttggtag
     5401 agcccgacat ggatgtattt tccaaccgct ccagcgacgg catccttggt tttcaaagga
     5461 cgttccaaac ctggactggt aatttctagg aaatattgtt ctgggaaggg atctggcttg
     5521 atggtgtcta ggacaggact gatcatttct gtcaagtctg ccgtgtcgtt caaggtaatt
     5581 ccttcgggtt tatctacaaa aatactgaga atcatgtcac tgccaatctt tccatactcg
     5641 atatccacga gttcaaaagg agcttctatg acaggttcta caacttctct gactaattct
     5701 acgattgttg cgattgcgtc cacctcctca taagcaagag gcgaagatat ttccccgcct
     5761 cacttttcat attcttacta tcagtatagc acgtttgcca acttatgtaa agcaaaagca
     5821 cttgtacagc ctaattttag gctatctctt aaaattctgc ctcaactcgg tagataactt
     5881 gccccttgtt tgagaatttt tgctcgtatt ctgtcatgac attgccttca aaatcactgg
     5941 catgcaaatc tagccagaca ccattgagtt tcatgccata ttgagaaaag ctcactaaac
     6001 tgtactcaaa caagccacgg ttatccgtct tgaaatgaat ttctccattt tcaggcaaga
     6061 tacgtttgaa ggtatccaaa aaggtcttgt aggtcaaacg acgcttttca tggcgttttt
     6121 tcggccatgg atctgaaaag ttcagataca agcgatcaat ctcaccgtct tcaaagtagt
     6181 cagtcaagtc agaaccatct acccacaaga gcttgatgtt aggcactcca acttcaagca
     6241 ccttgtccaa agcgtagctc aaaacagact tttgaatatc aatcccgata tagttgatgt
     6301 cagggttttg cttggccata cctgaaacaa aggcaccctt tccacttcca acttccacat
     6361 gaatgggatt atcattgcca aacaagtccc gccattttgc cttggcttcc aagggattga
     6421 ggaccacata ctggggattt gcctctagta attctgttgc ccctttacga tttctaactc
     6481 tcatcttctc tttccatact tgtctcggaa atgacgcaaa ccatgaatct cccgattgac
     6541 attttctaaa tcttggttca tataatactt ggaaatctga ctcaaataag acaattgacc
     6601 ataccaatac aatttactta ataccgtttg attgtacttg taaccgtagt aggtcaacca
     6661 ttccttccac tgatgttctg aaatataatg gcagagcata tgggccacat caaacatgcg
     6721 atcggtcaag cgaaccgaat cccaatctac taaataaatc aagccactat ctgtctcaat
     6781 ccaattacta tgtcgtacat ctccatggac aatggtcgca tggtcctctc taaatcctgg
     6841 aatagtctga cgtaaatcag ccatcacttc actgataaaa tgatttttac gcaaagcatc
     6901 tggagccgtt tcttgccaag actgtagtaa atctacaggt gtttccatgg catagcccaa
     6961 acgactcaat tgtgtcatca acggacgtga gcgatgaaga cgggttaaaa tattgacgat
     7021 ttgcttacga ttcatatcat agggggtcaa tatcttgcct gtcaaccatt cttgagcaca
     7081 catatcacgc ccatctgcca aacgacgact ccataataat tgtggagcaa tttgttctct
     7141 agctagacca ggtaggattg gagaggtgtt catttttaca aagatgcgct tcccatcagg
     7201 atagctaccc atataagcct tgccactttt cccaggtatg ggagtcagtg ttagctcatt
     7261 atcacccaaa tccatttctt tcctccgtat aaagtttcct tactattcta ctagtttttg
     7321 gcctattcgt caaccactct aacccgattc tcaaagaaaa gcctctggag tggtttgggt
     7381 tatcattata gaaagaaaaa ggtaagcaca atctcctact taccttttca tgatttttat
     7441 aaataatata agagtggcca actgttgtaa agcatatgga ctagagtaga aacccataag
     7501 ttttggctct ttttataagc aaggcccagc aacaagcccc caagtagata aaaaataaac
     7561 gaagggacat tagaaggtcc atgcatgaaa gaaaagagag aggaagttag cacaagccct
     7621 aaccaagaat tgtcaaaaac cgcaccttga agaagtcctc tgaaaatgag ttcctcctgg
     7681 atggggccaa aaactgaggt agtcaaaatc aaagacaggg aaattcctct gctgacttcc
     7741 gccaagtgtt ggacccctga gccagaagaa acagcgaaga aatgaatata aaccagcgtc
     7801 tcaagtacac ttagaagaaa gattgcaatg aaaagcaaaa gttgtttctt gcttaacatc
     7861 ccaaaagaaa tcatttcaaa ctttctagca taagcaacac tcagcgaggt tacaagaaga
     7921 cttacaagaa tcaatgcaga ttcattttga aaaaaatccc catggttaat cgtataagga
     7981 actataatga caattattag tactaaaaat ccaaaacaca aggcatgaaa tttatcaaaa
     8041 aactccataa aattatcctc ctcaacaaac agacttccta cacgtcattc tttagttcta
     8101 gcctttccaa aacaaaccat tttatactct tcgaaaatca aattcaaacc acgtcaacgt
     8161 cgccttgccg tactcaagta cagcctgcgg ctagtttcct agtttgctct ttgattttca
     8221 ttgagtatta gtaaccaaaa tccgaccaca tagccagccc ctatgaatat agccattaaa
     8281 gctagcatgg aatttaggaa attaaaaacc accgcagata caaaggttag cacaaaaaca
     8341 ttaaaagcaa tggtgtcaga agccaagact agaatatagg gtgtcaaccg atctaaagtt
     8401 ttggaatcta ggaaaaataa gtgtttatac atgatgacct cctctatggc tgaaaagcaa
     8461 gccttttgtt tttttacccc aagaccctat gtagaaaagt gagcaaaaac gggaaggtcg
     8521 ctacaatatt attgatcaca tgcaccgcat aggatggata aatgctcttg gtatagcggg
     8581 tcaaaccagc aaagatgatt ccaactgttg caaagacgaa gatatctaac agactaggca
     8641 ggcttgaaaa atgagggaga gcaaataaaa tagaaggaag aagcaaatca agaccaaatc
     8701 gcgaatgctt aaagaaagca tgttgcagta attctctata gattaactct tccatcagtg
     8761 gaaccagaaa gaacagggct atataaatac ctagctctgc aaagttagtc ccactataac
     8821 caatcaatac agcccaacct tccgcagttg actgaacatg tttagctgtc tgaacgttaa
     8881 aagagatctg gaacactacc actaatactg tcaaaatcga ataccaaagc catttttttc
     8941 ttggaatgcg gaagagataa ccatggcctg tcttaacaag aaccacaatc atgactccaa
     9001 taaaaagtaa actcaagata ttttgaatcc agacgaaatt accaatctgg gaagaaaatt
     9061 gccaataatt ttggacgata agcgtcagct gagaaagacc aaatacgaaa aataagtaag
     9121 agaagactgc acttattttg aatagaagtt gatacttttt catagaaatc ctccctacta
     9181 tgacctcacc ttgtcaggct ctactgctgt aagattaaga agacagtttg ttttttttaa
     9241 ggctaacctg actactagat aatagataca ttaaggcatt aaagacaatg aaaatatgtc
     9301 catagaataa aatcaacctc gcatccaaac caagataaag tttgattatc aaaaagatga
     9361 gcaaaagaat ttgaaaccat aaggtttttc caaaaataaa tttaaagcga tttcgaatat
     9421 ctacttcctt gatttttacc gccacccctt tattagcaag aaggaaaact cctgcttcaa
     9481 acaaaccact gtaaagaaca agccacccaa tagatacgat agagatttgt aaaaatgtcc
     9541 ctaaaagaat atccaacaca ctactcaaga aaataacaaa aaataatctg tatttcatat
     9601 taaatacctc cattcattta tttcactaac aatttaatag agccttctac tcaaatatcc
     9661 tgtcagaaaa ggatagaaag ctacttttta taatacttca agccccacat gagcagaagc
     9721 gtgataaaca agcagagaat acacctatat aaacgattag ttgttgatag aattctgttt
     9781 ctgaaatacc tctatacaaa caaatgacaa acataaaatc tgccaagccg ataaacataa
     9841 gttgattggt tctaggacta accaaatcat catttactta tatttaagag tatctctttt
     9901 atgttagtgt atgttagcac tgaaaagcaa gacagaccaa taatatttaa aatgaacagt
     9961 aacggggtta agtctctaaa aaaattatct actgacacta caagaaatac tatacatatt
    10021 atagtcgaaa ctatcttttt cttatccata attatttact cctttcctaa caaatccagc
    10081 ttatcaatca agagcgattt ttaacataat gtagcagcac ccgttgcaac tttgacaatt
    10141 tcagtatagc actatttgtc aaagtttttc atccaaatct tgaattgtca tcaagacatc
    10201 ttaaattgca aaaactgcat tagcctctac tttttataat acttcaatcc ccaaatgagc
    10261 agaagcatga tggtcaagca gagaatagcg ccaatgtagg caattatttg ttggtaggat
    10321 tctcctgctg tgatccctct atacaaacaa ataatagaca taaagcctgt caagccgata
    10381 aacatgagtt gattggttct aggactaacc aaatcatcat cttcaaactc tcttaatctc
    10441 atttccctag taagataaac agtaaccaaa atagaagtca agttaataac cactaaaaga
    10501 aattggaaaa ctgacgaaat agaaatagat aagtagaaac aagcaaaggc aactgaccca
    10561 ggaacaatct cacaaagaat atgattcttt ttaatcaaga aaatctttca tttcttttct
    10621 ttctttttaa ttaaagaaaa atagatcata accgcaatca tatagactat ggtataaaat
    10681 agctgatacc aagcactctc cctaagcgga tatagaaaga tggacatgat tagatacaga
    10741 acgaaaataa tcagtatttt tttcttcata agatttcctc ctaaatgtgc gatttatctt
    10801 agttgagcaa gaacatttac actgctagta tagcacttat tttgaccttg gatcactcaa
    10861 atcataaatg gtcatcaaaa cctcttgaat tgtaaaaatt aaaaaagcaa gcatgaaaaa
    10921 catactttcc tctttatatt gtattgatac caacttgttt gtagactttt catcctgcta
    10981 tcacatatca ttttgacagg cgaaacaata ttaaagaaac tcccctgtaa attaagctag
    11041 caaatacagg ggagaaattt attttttagg gggtactatc tgtatccttt ttgggaaatt
    11101 ttgaaaatat ttttctaatt aaattatcca tataaggacc aaatatacca actactaaac
    11161 caataataaa acttttaaaa tccataatta ccaccaacat gttgctgcat aggctacacc
    11221 tccaagtata gctccacccg cagcaccagt tgctgcacct tgccatgttc ctgttttaat
    11281 gcctagttga agacctcttg ctgctgctcc tccaacacct gctttggcaa aatctcccca
    11341 attgcatccg ccaccttcaa cgcaagcaag catttcagta tccataacag aaaattgtga
    11401 catcattttt gtatccatga caaatactcc ttttttaaaa aactaaaata aatcagaata
    11461 gaatcctcat aattttacta taagtcttac caacttagtc ccaatttatc accaaccata
    11521 cctcctaagc atgttaatcc acccccaatt gcaccaatgt gtgctccaac aaatgcacca
    11581 gcaagtccag ctactcctaa agtggccaaa cctgctccag ttccaccagt tataattccc
    11641 gtagtgactc ctgtaatcag tgcattttga caatcagtgg agctataccc cccttcaact
    11701 ttcgcaagca tttcagtatc cataacctct aactgtgaca acatttttgt attcatgatg
    11761 aatacctcct ttttattttc aatttgttac caaagtctta aattcaataa acaaatagat
    11821 tttttatagt atctttttga ttttcttaaa aaagtatata cgtctactat cttcttaaaa
    11881 gtagcagtac ctatttttta gtctaagatt tcaataatct tgagtatcta aaatatctta
    11941 atttcgttat tctccttgca ataaaaagtt ttactatact atttattaac ttgcagaaag
    12001 caaaaaatat tagtaaataa tagtttatag ttaagttttt tattcctacc aatccatcaa
    12061 ctaagtaaag catcaacgat tacataaacg attgataata taattaaaat tttgctaact
    12121 atcttattct catcattctt agataacttt gatattttgt aagtaagtaa ataagacagt
    12181 aaattaatag cgataataat actatattta agaatcataa tcttacaaag aggacataat
    12241 tcctgaacct acacaaataa gtgttgctgc tcccccagtt atcggaccag tcgcagcagc
    12301 taatagtact gctccaatac aaccaccgat tgcagatcct aaattgcctc ttcctccact
    12361 aactatttcg agttcttcat tatccataac agaaaattgt tccatcattt ttgtattcat
    12421 gacaaatact ccttttttat ttttgtcttg ttgtaacttt gataagttta gtatatcatc
    12481 gttttttaaa atttttcatc cagatcttga attgtcatcg aaacgtcttg aattagcttt
    12541 tttatttcaa gccacctcta tttcaagcca cctctaaatg tttaaaaaaa ataatttcta
    12601 atcacttttt taccattcag gaagttttaa tgactattca agatttcata aaatatgaac
    12661 ttagttttat gacataatag acctatccac tatatgaaag gaattgccaa tgacttctta
    12721 taaacgtaca tttgttcctc aaatagatgc gagagactgt ggtgtcgctg ccttagcctc
    12781 gattgctaaa ttctatggtt cagatttttc tctagctcac ttgagagaac ttgcaaagac
    12841 caataaagaa gggacgactg ctcttggcat tgtaaaagcc gctgatgaaa tgggctttga
    12901 aacaagacct gttcaagcag ataaaacgct ctttgacatg agtgatgtcc cctatccatt
    12961 tatcgttcac gttaacaaag aaggaaaact ccaacattac tatgttgtct atcaaacaaa
    13021 gaaagactat ctgattattg gtgatcctga cccttctgta aaaatcacta aaatgtcaaa
    13081 agaacgcttt ttctatgaat ggactggagt agctattttt ctagctacca aacccagcta
    13141 tcaaccccat aaagataaaa agaatggtct actaagcaag cttccttcct ctgattttca
    13201 aacaaaaatc tctcattgct tacattgttc tctcaagctt attggtcact attatcaata
    13261 taggtggttc ttactatctc caaggaatct tggatgaata cattccaaat cagatgaaat
    13321 caactttagg aatcatctca gttggtctgg ttatcaccta tatcctccaa caagtcatga
    13381 gcttctccag agattatctc ctaaccgttc tgagccagag attaagcatt gatgtgattt
    13441 tatcctatat tcgccatatt tttgaacttc ccatgtcttt ctttgcgaca cgtcgtacag
    13501 gagaaatcat ttcacggttc acagatgcta actctattat agatgtcttg gcttctacca
    13561 ttctttctct ttttctggat gtttctattc tgattcttgt agggggagtc ttgctggcac
    13621 aaaaccctaa tctcttcctc ctttctcttc tttccattcc tatatacatg ttcatcatct
    13681 tttcttttat gaaacctttt gaaaaaatga accatgatgt catgcaaagt aattctatgg
    13741 ttagctctgc cattatcgaa gatatcaacg ggattgaaac tataaagtcg ctcacgagtg
    13801 aagaaaatcg ctatcaaaat atagacagcg aatttgtaga ttatttggaa aaatccttta
    13861 agctcagtaa atattctatt ttacaaacga gtttaaagca gggaacaaaa ttagttctga
    13921 atatccttat cctatggttt ggcgctcaat tagtcatgtc gagtaaaatt tctatcggtc
    13981 agctgattac ctttaacaca cttttttctt actttacaac tcctatggaa aatattatca
    14041 acctccaaac caaactccaa tctgcgaagg tcgctaataa ccgtttgaac gaagtctatc
    14101 tagtcgaatc tgaatttcaa gttcaagaaa accctgttca ttcacatttt ttgatgggcg
    14161 atattgaatt tgatgacctt tcttataagt atggttttgg acgagatacc ttaacagata
    14221 ttaatctcac gattaaacaa ggagataagg ttagcctagt tggagttagt ggttctggta
    14281 aaacaacttt agccaaaatg attgtcaatt tctttaaacc ctacaaaggg catatttcca
    14341 tcaatcatca ggatattaaa aacattgata aaaaagtctt gcgccgtcat attaattacc
    14401 taccccaaca agcctatatc tttaatggct ctattttgga aaacttaacc ttgggcggta
    14461 atcatatgat tagccaagaa gatattctaa aagcttatga attagctgaa attcgtcaag
    14521 acattgaaag aatgcctatg ggctatcaaa ctcagctctc tgatggagct ggtctatcag
    14581 gaggacaaaa gcaacgaatc gctctcgctc gtgctctttt aactaaagct cctgttttaa
    14641 tactagatga agctactagc ggtcttgatg tcttgactga gaaaaaggtt atagataatc
    14701 ttatatccct aactgataaa accattctct ttgtagccca tcgtctcagt atagccgaac
    14761 gaaccaaccg tgtcattgtt cttgaccagg ggaaaatcat tgaagttggt agtcaccaag
    14821 agttaatgca ggcgcaaggc ttctaccatc atctattcaa taaataagga gaatgtcatg
    14881 aatcctaatc tttttagaag cgtcgagttt tatcagagac gttaccataa ctatgcgaca
    14941 gtgttaatta tacctctttc attactgttt actttcatct tgattttctc ccttgttgcc
    15001 acaaaagaaa ttactgttac ttcccaagga gaaatcgccc ctacaagtgt cattgcatct
    15061 attcagtcga ccagtgataa tcctatcctt gctaattatt tagtggcaaa tcaagtagtt
    15121 gagaaaggtg acttactcat caaatactct gaaacaatgg aagaaagtca gaaaactgcc
    15181 ttagcaactc aattacaaag acttgagaag caaaaagaag gacttggaat tttgaaacaa
    15241 agcttagaaa aagcgactga tcttttttct ggcgaggatg aatttggcta ccataatacc
    15301 tttatgaatt ttactaaaca atcccatgat attgaactgg gtatcacaaa gactaacact
    15361 gaagtttcaa atcaagccaa tcttgccaat agcagttcat cagctattga acaagaaatt
    15421 acaaaagttc aacaacaaat tggagaatat caagagctga gagatgctat cataaataac
    15481 agagcacgct taccaactag caatccacac cagtcaattt tgaatcgtta tcttgtagcc
    15541 tcacaaggac aaacacaagg aacggcagag gagccatttt tatctcaaat taatcaaagt
    15601 attgcaggtc tggaatcatc tatcgcaagc ctcaaaattc agcaagctgg tatcggaagt
    15661 gtagcaactt atgataatag tttagcaacc aaaattgaag tactccgcac tcaattttta
    15721 caaacagctt ctcagcaaca actaaccgtg gagaatcaat taacagaatt aaaagtacaa
    15781 ctagatcaag caacgcagcg cttaggaaac aataccttaa ccgctccaag taaaggtatc
    15841 gttcatctga acagcgaatt tgaaggtaaa aatagaattc caactggtac agaaattgct
    15901 caaatattcc ctgtcatcac agatacaaga gaagtactaa tcacttacta cgtatcttct
    15961 gactatctac ctctactaga taaaggacaa actgtaagat taaaactgga gaagattgga
    16021 aatcacggca ccaccatcat cggccaactt cagacaattg atcaaactcc taccagaaca
    16081 gagcaaggta atctctttaa attaaccgct cttgcaaaac tatctaatga ggatagtaaa
    16141 ctcatccaat atggcttaca aggtcgcgtc actagtgtaa ctgcaaagaa aacatatttt
    16201 gattatttca aagataaaat tttaacccat tctgattaat tttcagataa cactctataa
    16261 ctatttatta tcttatcaaa aaggagaatc ataacatgga taagaaacaa aacctagctt
    16321 catttcaaga actaacaact accgaactca accaaattac aggtggagga ctgtgggaag
    16381 atatcttata cagccttaat ataattaagc ataacaatac gaaaggactt catcatccaa
    16441 tacaactata aaaaataaga ccgagtaaca agaactctcg gtcttatttt tttcatcatt
    16501 ctgtaggtat catagtaagc acctgacgaa agacttgatc ttgacaggta gtatttaaac
    16561 tggcattggg ataactttcc acaatcttca taacggtata gagaccgaca cctctctcct
    16621 cccctttaga actaactcca aaggagaaga tttcagaaat atcgatgccc tcttctttga
    16681 tggaattttc gatgatgaag gtctcctgtg ctccactttt taaaaaggca attgaaacat
    16741 gaggttgacc ggcctctgca ctcgcttcaa tagcattatc acaaaggata gacacaatgg
    16801 ttagaaaatc aagcagtctc atcccctcaa cctgaatctc ttcaggaact tcgacattaa
    16861 agacaatgtt cttatctcta gcttttataa attttccagc taggagactt ttgagggcac
    16921 gatcccgaac attcaccaat cggccaaggt catatttatt gtcctgcaat tttttactag
    16981 aatcctttaa gaccaagtca tagacctctt ttatctgctc catatcctcc tcttcaatac
    17041 ccagacgtaa acttgtcaag aggttggtgt agtcatggcg aaaactcctt acttccttgt
    17101 aaagttcctc tatatgccga ctatagcgtt ctatatctct atagcgcaag acctgctctt
    17161 ggtccagtct atcatggagt ttgtccttca aataggtatc caatttcttg ataaccccca
    17221 taaaaaatag gaggtagaac actaggatga gatggcgaac agtcgttgat tgaatacctt
    17281 gctcatattc aaagtaagac agactttgta tcaccaaata gtaagccccc attatccagt
    17341 taatcttagt cagggacttt tgaaaacctg tatctagaat ctcccttctc aaactagtaa
    17401 aatcatagtc caaccatttc aaaaaggcta gagaaatgaa gaaattgaaa attattatac
    17461 ataacccagt gaatgagtag ccatcatata cttgcccttg tcccaaaaat ggaagcacaa
    17521 aataggagac tcctctataa aagagattca ccaatatcat tggaaagaga ccataaaaga
    17581 aaaggagttt tttaggaagc cctcttaaca ataagaaaga caagcctatg ccgtacaagg
    17641 gttccataaa ataagatagg taaacatttc ctactatata gctaatcatt acaaaaacaa
    17701 agaccaacag tatcttcaaa agaaaggcct taaaaatcct ctcgaaagta agattaattc
    17761 catccacctt aaagaaaatg acaatttcta gcccattagt aataagtgta tgcaataata
    17821 tccaaacaat attcataaac tctcctagtt cagtgtaagt tattaatagc ctcagacact
    17881 tccctgacct tataacgcgc gatcagacaa cttccaccat tgggaaaaaa aaggagtttt
    17941 tctttcttat ccaaatgcac cacatttgca ggattgatga gaaaagagcg atggcactgc
    18001 aagagacggg gttcctgctt gaaaacctcc tctaaactcg ctgtaaattc cagcctgtct
    18061 gtcttggtat agagaataac acgatgggct ctgggagacg tttcgagata gtaaacctct
    18121 ttaaaaggat attggaattg ggcaaatttt gatttaaagt aaaagcaatc ttccgccaga
    18181 cttttactat cttgactatt ggcatagagg aggtctgtct cgattcgaga ttcaaactcc
    18241 tctgccgaaa gggccttatc aatatagtcc agagcagaca cttggtagcg aaaggacagg
    18301 ggcataaact ccgagtgagt cgtcacaaag acaatcaggg cataaggatc ccgatcccga
    18361 atctttctag ccacttccag tcccttcatc tcttcatttc gaatctcaat atccaaaaag
    18421 aatagctgat gggccccctt ctcatgcact tcagccagca gttggtccgg cttgccaaat
    18481 acctcaaaag agctaggaat gatatgatgt gctttcaaaa gtttctcaat cgtcgtttca
    18541 attctagtct gttgggaaaa atcatcctct aaaacaaata ttctcatctt cttactctcc
    18601 ctctttcaac catttttgac gaatttctct atagcgacgt ctggcatact tgacagcgta
    18661 ttgaccttct tctccgagaa aaaggattct ttcttgaaaa tcaatcgatt ttaatttatc
    18721 aagattaacc aaacaatttc gatgacatct catcaaggtt tccccacatt ggttctcaag
    18781 attacttaaa ttttgaagta tattaaaact agcttcttct gtaacaatct gtacggtatg
    18841 ggctttagtt ggatgtgttt ggatatagta gatatcgtcg atgtttactt tatagactgt
    18901 tttctgcgtc tgaataatca tatatttcat tggattctcc tcctaagaaa agaataacag
    18961 aaaaggtcta gcccaagcac acccaatcct aaacagtctt tgaaaactcc taaaaggatt
    19021 attttctaca acatcatgat gagcttacaa ctattttatc ataaaattca ctcagcgcaa
    19081 ttcaagacat ttcaatgaca attaaagatt tgaataaaaa aaaagaatta aaagtgataa
    19141 actaacagta tcaaaacaca gttgccagaa gtaagactgg cacccagatt aaaggaggca
    19201 ttcccatgac agatacagac cccatcaaaa gagctcatac tttgattact gacttaaaca
    19261 aagcctacca agcatgcaaa caggcaagcg ctgacgacgt ccgctttcag gagcaattaa
    19321 actctattct tggttttcta gccaaggctg aaacagtgga taatcgattc ttgattgaac
    19381 tagaaaaatt ttaccagact tccagtcttc tcatgggact cagcgctctt gatccagatg
    19441 ctccaactcg cgccgcttgg cgggcctatg accgcttcca ctttgaccaa gtcaagacca
    19501 agttaatact caatgaaaat caaagagcaa actaggaagc tagccgcaag ctgtacttga
    19561 gtacggtaag acgacgctga cgtggtttga agatattttc gaagagtata agtctctacg
    19621 gaccaaccat tatcctgtag taacaaaaaa gaagttgaga cagactgaac tcaacttctt
    19681 ttttagtgtc gtatcagcaa tgttagtcct gcatctgacg ttttacctga taaggcaaat
    19741 acaagactag taaaaccaaa ccagctccta gtaaggctag aagggctagt ttttcttgga
    19801 aggtaatcaa cccaacaact aattccacaa gtaaaacaaa actggtcaat cctcgaacta
    19861 cctcctgtaa gcctttttcc ttttgcccct tgtccagcgg aaagagttgg gtcaaatact
    19921 ggtagtcaaa ggcatgatag agggccagca actggaagag caagaggtag ttaaagagaa
    19981 ctaccactgc tgtcgcaatc caagcttgct cgataaaaac ctgcgccagt acggaaagta
    20041 agagaagacg aagactgaga gcaaagaggt cgccatttcg cagataagaa cgcagataga
    20101 gattttgcca aatcttccca ggcaccttct gaacagcctt taaaataaag tccagatagg
    20161 cacgacgctt aacgctgttt gaaattccct tgacctgcgt aaagagggca aagaaacgaa
    20221 gcaagacttg cttacgcttg ctttcttgag aaataagata gtcccagtcc agtccagttt
    20281 cagtgaaaaa tttgctggcc ttttgacaaa agtggaaata ttttcctacc cccaataaaa
    20341 gcacatagag cagaaaaact ggcaagccat aacccattgc caaaaataaa ggcgcaaata
    20401 acagcaagaa aagggtctgt acaaagagcc aaaagactag ggaaatgcca gtttgacgct
    20461 tgagatggag cttgatttcc tcttctccaa ctaagagaaa gagcttgtct ggagcctcca
    20521 tataggtggc aattcctccc caaagtaaaa gtaaaacaga cgtaattcct acaaacaaaa
    20581 ggataggcca atgattttca ggaaaatgtt gtaagagttg actgtactgg taggctagaa
    20641 agcccaacag gacaagcagg aacaagacaa agtggtcatt gagcacatag cgcagataac
    20701 caagacactc cttacgaaag gcctgctttc tctttaaaaa caagtctttc ataggtcctc
    20761 ctcttttgtc agagccaagt aaatatcatt caaactagcc tcaggcatat caaaggcttc
    20821 gcgtagttgc aggagattgc ctttggcacg cacctctccc ttgtgaagaa tgacaaaggc
    20881 atcacacatc ttctccgccg aatccagcac gtgggtactc atgagaatag acttgccctt
    20941 ttgcttctcc acttccaaaa gctgaatcaa atcagaaata gccagcggat caagaccaag
    21001 gaaaggctca tccacgatga aaaggcttgg atccaccaca aaagcacaga taatcatgac
    21061 cttctgcttc atcccttttg aaaaatgaac agggaaccag tctaatttct ggtccagacg
    21121 gaacatcttt aacaagggct ctactcgttc gaaagccact ttttgctcaa taccgtaagc
    21181 catagcaacc gtttcgatat gctctctgag ggtcaattcc tcatacagac taggcgtctc
    21241 aggaatgtag ccaatctgct tgcggtagct agtcgcatct ccttgcagag tcaggccatt
    21301 gatattgatg gagccactat aaggtgccaa cagaccgata atctcattga tcgtcgttga
    21361 tttcccagca ccattgagac caatcaaacc gaccaactgc ccactttcaa cagtaaagga
    21421 cacatctttc aaaacaggaa catgaacata gccacctgtc aggtttttaa tttctaacat
    21481 attttctcca aatctggtat aatgtagcta tattatatca aaatttagta cagtagaggt
    21541 agattttatg tcagattgca ttttttgtaa aatcatcgca ggggaaattc ctgcttcaaa
    21601 agtatatgaa gatgagcagg tccttgcctt tcttgatatc tctcaagtaa cactaggaca
    21661 caccttggtc gtgccaaaag aacactatcg caatcttttg gagatggatg ctacgagcgc
    21721 cagccaactc tttgcccaag taccaaaagt agctcaaaaa gtcatgaaag tcactaaggc
    21781 tgctggtatg aatatcattt ccaactgtga agaagtcgct ggtcaaacag tttttcatac
    21841 tcacgttcac cttgtgcctc gctacagtgc tgacgatgac ctcaagattg attttatcgc
    21901 ccacgaacca gactttgaca aacttgctca agtcgctgaa accatcaaaa acgcttaagg
    21961 agttgctatg aaattatcca acctactgct atttgcagga gctgcagccg gaagttatct
    22021 ggttacaaaa aatcgccaaa ccatcacaga tgaagtcttg aataccactg accgcgttca
    22081 agctatcaag gacgatgtgg atattatcca aaacagcctg caaatcatta accagcaaaa
    22141 agaacttatc aaggaatacc aagaagactt gacttacaag tttaaggtct tggaaaagga
    22201 tatccagact agactagctg tgataaaaga aatgcaggga actgaagata agtaaaaaga
    22261 gccccccggc tcttttttaa aacgtaaaca agttatagtg aattgaattt agaatagcac
    22321 accatagttt ctaaagcatt gttagagatt actttaaaat cctcttatca atttgttcat
    22381 attctatttc aatctattat atatatccca tcaactatgc atcataattt aggtaactca
    22441 tactcaataa aaatcaaaaa gcaaactaga aagctaggca cagactgctc aaaacaccgt
    22501 tttaaggttg t
//
LOCUS       DBERDS010000029        22202 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.029, whole genome shotgun sequence.
ACCESSION   DBERDS010000029 DBERDS010000000
VERSION     DBERDS010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22202
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.029"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(49..1185)
                     /gene="dnaJ"
                     /locus_tag="ACL73E_001313"
     CDS             complement(49..1185)
                     /gene="dnaJ"
                     /locus_tag="ACL73E_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGS0801278.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1587..1943)
                     /locus_tag="ACL73E_001314"
     CDS             complement(1587..1943)
                     /locus_tag="ACL73E_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGS0801279.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(1945..3768)
                     /gene="dnaK"
                     /locus_tag="ACL73E_001315"
     CDS             complement(1945..3768)
                     /gene="dnaK"
                     /locus_tag="ACL73E_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGS0801280.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4248..4772)
                     /gene="grpE"
                     /locus_tag="ACL73E_001316"
     CDS             complement(4248..4772)
                     /gene="grpE"
                     /locus_tag="ACL73E_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGS0801281.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4799..5833)
                     /gene="hrcA"
                     /locus_tag="ACL73E_001317"
     CDS             complement(4799..5833)
                     /gene="hrcA"
                     /locus_tag="ACL73E_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGS0801282.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(5997..6507)
                     /locus_tag="ACL73E_001318"
                     /pseudo
     CDS             complement(5997..6507)
                     /locus_tag="ACL73E_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            7115..9448
                     /gene="hsdR"
                     /locus_tag="ACL73E_001319"
     CDS             7115..9448
                     /gene="hsdR"
                     /locus_tag="ACL73E_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGS0801283.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKAHRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9461..10978
                     /locus_tag="ACL73E_001320"
     CDS             9461..10978
                     /locus_tag="ACL73E_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS0801284.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINAIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILPLDQGFKNRQAQTKQSPSSFIEII"
     gene            complement(11067..11216)
                     /locus_tag="ACL73E_001321"
     CDS             complement(11067..11216)
                     /locus_tag="ACL73E_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGS0801285.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFYKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            11181..11300
                     /locus_tag="ACL73E_001322"
     CDS             11181..11300
                     /locus_tag="ACL73E_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGS0801286.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(11396..12742)
                     /gene="glnA"
                     /locus_tag="ACL73E_001323"
     CDS             complement(11396..12742)
                     /gene="glnA"
                     /locus_tag="ACL73E_001323"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGS0801287.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(12779..13135)
                     /gene="glnR"
                     /locus_tag="ACL73E_001324"
     CDS             complement(12779..13135)
                     /gene="glnR"
                     /locus_tag="ACL73E_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGS0801288.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(13212..13739)
                     /locus_tag="ACL73E_001325"
     CDS             complement(13212..13739)
                     /locus_tag="ACL73E_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGS0801289.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDKSVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(13875..15071)
                     /gene="pgk"
                     /locus_tag="ACL73E_001326"
     CDS             complement(13875..15071)
                     /gene="pgk"
                     /locus_tag="ACL73E_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGS0801290.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(15161..20101)
                     /locus_tag="ACL73E_001327"
     CDS             complement(15161..20101)
                     /locus_tag="ACL73E_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGS0801291.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANPELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFALSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDNLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            20394..22025
                     /locus_tag="ACL73E_001328"
     CDS             20394..22025
                     /locus_tag="ACL73E_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGS0801292.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGFGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT         6443 a         4611 c         4199 g         6949 t
ORIGIN      
        1 ccatggcaag ccgacgctga cgtggtttga agagattttc aaagagtatt attctccatc
       61 aaaggcatct ttaatatgat caaagaagcc ttttttcttt ggatttactt tcaagtcacc
      121 agcagccgcg aattctttca aggctacttt ttggcggtcg ttcaagcctg tcggtgttac
      181 gacattaaca gtaacgtatt ggtcaccaac tgcaccgcca cgaaggctcg gtgccccctt
      241 actacgtagg cggaatttct taccagtctg agttccctct ggaataacca attcaacatc
      301 accgtgaaca gttggaatat ctactgtatc accaagagcc gcttggacaa agttgaggtt
      361 gagattgtag aagatagtcg ttccttcacg ttcaaacttg tcgctagctt ccacagaaac
      421 tactacatac aagtcaccat aaggtccacc gttaaagcct gcttcacctt gaccagcgag
      481 gcgaatttgt tgacctgttt ccacaccagc agggattttc acatgtacgc tatgagcttg
      541 tttctcatga cctgttccat gacaggttgt acatggatat ttgatttctt ttccttggcc
      601 gtgacagaca tcacaggtta cttggcgacg catcatacca agaggagtct gcgtatcgac
      661 gttaatgaca ccagcgccat gacagcgtcc acaagtgact ggacttgtcc ctggcttagc
      721 accagagcca ttacatgtac gacagccagc ttcacgatga tacttaactt ccttctcagt
      781 tccgaagata gcttcttcaa aggtcaaatt gacacgatac tggagatcat ctccttggcg
      841 aggagcgttt ggattgcgcg aagaaccgcc tccgccgaag aaacttgaga aaatatcctc
      901 aaaaccaccg aagccacctg ccccattgaa accgccgaaa ccaccatctc caccaaaacc
      961 accattggcg cctgcagcac catactggtc ataggcagca cgtttttggt cgtcactcaa
     1021 agtctcatag gcttcttgaa cttccttgta cttgtcctca gcaccaggct ccttgttgat
     1081 atctgggtga tattttttgg aaagcttacg ataagccttt ttgatttcgt ctgccgaagc
     1141 gtttttggat acccccagac gatcataaaa ttcagtattg ttcataattc aagatacaaa
     1201 gggcgtcaaa cggacacagc catctaggag ttttgacgac ggacgcttat gtcctagaaa
     1261 aaactatctt tttggcacag tccgtagccc gtgttcagtt acgaacaccc ttattccttt
     1321 ctattgatgt tctgaatcga accaccattt aggtcggatt caattccttt cttttatatt
     1381 tagtaagaaa ttctgaaacc cgtgttcagt tacgaacact ctttgttcct ttctattgat
     1441 gagacaaaac ccaaacaaat gagattccgt ccctttttat cgaaaaacag aggctgggtt
     1501 gcaacctctg caaataagta aattaacttt attttgattt taaatatcct ataagtacag
     1561 aaatatttat atatttttgt ctcttcttag tatttgccta tataattcca attgatcata
     1621 agaaatacaa ctactgtcca aatcatacca attatgaacg gtattacaaa tttatatgtt
     1681 tgtatttcta atgatatcat agctgatacc atcgccgata caaatgcaga caacaatact
     1741 gaagtaacaa aattccttac cgcttcatca tttttgacac aactatcatg ctcagctaat
     1801 ataatttctc tatatatagt caaacattct actggaatat tatctataaa accttttgct
     1861 gcttcatagt tgtcagcttg attacaaaaa tcattataaa cttttcgtgt attttttaga
     1921 tactcatcat ccaatacact catcttattt ttccgtaaac tctccgtcta cgacgtcatc
     1981 gcctgcgttt cctgttgctt gtgcgccttc tgctccttct tgagcttgtt gcgctgctgc
     2041 ggcttgttcg tagagtttca cagcaaggcc ttgagctttt tcgttcaacg cttcaagttt
     2101 cgctttcatg tcgtccaagt tgttgtcttc ttgagctttc ttaaggtcat caagggcagc
     2161 ttgggcagcg tcacgttctg cgtcgaagcc tttaccttca gtttccttga ttgtcttttc
     2221 agtcgcaaag attgcttggt ctacttcatt acgaaggtct acttcttctt tacgtttctt
     2281 atcagcttca gcgtttgctt ctgcatcttt catcatgcgg tcgatttctt cgtcagtcaa
     2341 acctgagttc gattggatga caatagtttg ttctttttga gttccaaggt ctttggcctt
     2401 aacagacacg ataccgttct tgtcgatgtc aaatgttact tcgatttgag gaattccacg
     2461 aggtgcagct gggatatcag tcaattggaa gcgtccaaga gtcttgttat ctgctgccat
     2521 tgggcgttca ccttgaagaa cgtggatatc aacggctggt tggttgtctg ctgctgttga
     2581 gaagacttgt gatttagatg ttgggattgt agtgttgcga tcgataagtt ttgtaaatac
     2641 tccacccatt gtttcgatac caagtgacaa tggcgttaca tcaagaagga caacgtcctt
     2701 gacatcacca gtaatcacac caccttggat agccgcaccc atagcaacta cttcatcagg
     2761 gtttactgat ttgtttggtt ctttaccagt ttcagcttta acagcttcaa caacggcagg
     2821 gatacgagtt gaaccaccaa caaggataac ttcgtcgatt tctgacaagc tcaaacctgc
     2881 atctgaaagg gcttgacgaa ctggaacttt tgtacgttca acaaggtcac gagtcaaatc
     2941 gtcaaatttc gcacgagtca aagtcatttc caagtgaaga ggtccagcct cacctgcagt
     3001 gataaatggc aagctgattt gtgttgaagt tacaccagaa aggtctttct tcgctttttc
     3061 agccgcatct ttcaaacgtt gcattgccat cttgtcagta gacaagtcga taccgttttc
     3121 tttcttgaat tctgctacca agtggtcaat gattttttgg tcaaagtcgt caccaccaag
     3181 tttgttgtcc cctgcagttg acaatacgtc gaagacaccg tcacccaatt caaggataga
     3241 gacgtcgaat gtaccaccac caaggtcaaa taccaagatt ttttcttctt tgtcagtctt
     3301 gtccaaacca taagcaagag ctgctgcagt tggttcgtta acaatacgtt ctacttcaag
     3361 accagcaatt ttaccagcgt cttttgttgc ttgacgttga gcgtcgttga agtaagccgg
     3421 aactgtgata acagctttgg ttactttctc accaaggtag tcttcagcgt agcctttcaa
     3481 gtattgaagg atcatagctg agatttcttg tggagtgtat tcttttccat ttgcagaaac
     3541 tttttcagaa gttcccatct tagatttgat agagataact gtatctgggt ttgtaactgc
     3601 ttgacgtttt gcagcatcac caacgatgat ttctccgttt ttgaatgaga ctacagatgg
     3661 agttgtgcgg tttccttctg ggtttgcgat gattttgctt tcagttcctt caagaactgc
     3721 aactgctgag tttgttgtac ctaagtcaat accgataatt ttagacatgt gtttttctcc
     3781 ttgttagtta attttctatt tttctttttg atactcttct taagtggcga cgccgtcaga
     3841 gcttgacttc gtcaatctct ttgactaaac tttgagccta aggtctcaaa atttgcgcaa
     3901 atagcaccac ggcgaagagt atcgtctttg gttcgcttcg ctcactatta caaagccaaa
     3961 catattttat ctttcttcat agtttattgt cgtttcggac aagttttcta ttatgtaaat
     4021 tgcgacacga ggagtcgaaa tcgattttat ttcgacgacg agttagtaag gaagctaggc
     4081 aaacgtcata gcgattgccg ttttctgacg agttgcttta gctaccgtca gaattgccga
     4141 atcgaacacg ccctaagctc tgagtaaaaa agatagattt tcttgtgttc atcgaacact
     4201 tcgtcaatct cctattttta ctgcgagctt tttacgagct ttgtatctta gttatacacc
     4261 actaccattg ctgggcgtag gatgcggtca tggagtttgt agcctttttg aaagacttgg
     4321 gcgatggtat ctactgggtg ttcatcgtct gctgggagag tttggatggc catatggtag
     4381 ttatggtcaa attcgccatc tgctgcgatt tcttcaattc cttcttcttt caaagcgtga
     4441 atcaagcttt cttgcaccat cgccaagccc ttcttcacat catctgtcaa accttcaact
     4501 gcaagtgcac gctcaaggtt gtcaagagat ggtaagattg cttttgccaa gtcctggcta
     4561 cgataacgtt gcaagttttg acgttcttca ttggcacggc gttggatatt ttgcatttct
     4621 gcatgagcgc gaagatattt gttttcgaac tcatctgcac gttcatttgc caagtccaac
     4681 tcagactttt caggagttgt ttcttcagct gtttccacaa cttcctcttc ttgaacttct
     4741 tctacttctt cattttttat atcttgggcc atgttcgcct cctttaatga tttcaatctt
     4801 aatgtacttc gtaatgatta ctgctgaggt agcggtaaaa atctgtcaac ttcatggtca
     4861 aaacacggtt gaccacattg atttgattga ttagctgttg gtaatccaga ttaactggac
     4921 cgataatggc tagaattcca actcctcgat aaggaatgag gaacttacta ctaatcactg
     4981 ctaggtcagc taaacaggac tcttgaccgt ctgcaacacg aacattttgc atctgatcct
     5041 cacgcaaccc ctcacgaatc tccaaggcca ccttttgcgg ttggtcaaag aactgatagg
     5101 ctgctagatt ggcaaaattc aagagatgga ccttgcccgc catcacaatg ttttcgttga
     5161 acatttcctt aaagatgtgt tcaaagagat cgatgacatt atccgttgtt gtaaagtaac
     5221 gctggataat ctgcggaatc tccgtccgaa tcttgtagtg aatatctaaa acggtgtgac
     5281 cgaggaaacg ttcctgaatg atgctcttca gtttcagcaa atcctcctgc aagaagttcc
     5341 ttggaatcag aaactgacta gtaaccgttc gcgactcgtc tagggtaaat accgccaagg
     5401 ctgtatgttg ccccaaaaca acgatatcaa aggctgtcaa acgttgcctg ctcggctcaa
     5461 catccagtgc cactaccgta cagccactca ggtctgttag taagttagca gcctcttgca
     5521 gaatatcctc caatttgaag aattcctgat caaaggcttt gacaatctca tatacctcat
     5581 tttcagccag ccggtcaaaa tccagtgagt gtttcacata gtactgaaaa ccagcaacac
     5641 ttggcatccg accgcttgaa gtatgagcct tctcaagcaa cccttgtttt tctagttccg
     5701 ccatgtcatt acgaatggtt gcactgctag agttaataga ctcttgcaag gcttttgatc
     5761 cgacaggttc gtgcgttttg gtaaagatgt caataatcag atttaaaata tcctgctgac
     5821 gctctgtaac catctcatca ctcctctctg tctgatcaat tagcactcaa tgcatccaag
     5881 tgctaactca tgattctatt atacaccctt agaagagaat gtcaagacaa aaactcaaaa
     5941 aattagcact cttttatcaa gagtgctaaa aatcaatctg aagacctaga accttgctat
     6001 tcatctactc ggtatttcct ttttagtctg aaataaccat aaattagata agaaatcaga
     6061 aaagcatata aaacaaaaat aagaaagaaa gacatagaaa gatcctctct aaacaaactc
     6121 atacaaacaa caagaccacc tgagaaagta gctgtacagg aacgaagtct agattgcata
     6181 acttcccatt tgagcccttt actcatacag acttgatcct ctggaagtaa atcagaagac
     6241 gatttacgaa gaatcgaaca agaacctact cctatcaatt cccaacctct atctctaaaa
     6301 tcttgcagtt catgcttata cttttttaag aaatctagaa tcatagatac ggtagatgac
     6361 atcgtctggt tgacattggt caaaatagaa caaaccaaaa cgactcgttc tatacctcca
     6421 acctttcaaa tgcatctcat gtaaatgttc ttcttccttg tccaaatcaa caatggtgaa
     6481 aatccgaaat tctactctgc tattcattgt cttaccccaa aattagaaaa catgcctggc
     6541 gttatttatt agataattct ttccactttt gactcaatct ccaaaaaata taagaaatct
     6601 gaatcgcaaa aactatcaat aaaacccaat ctattatgaa aatcaaaaac actttccaac
     6661 tgaaagaact acctccagtg acaaactttg agaaaaacgg tagtagagct aaaaagagaa
     6721 ataaaatagg aagcatccgc attgttaaaa tccgtttggc ataaaaaaat ctttatttaa
     6781 acgaaaatat tatggcaaaa tttacgccag tttttgaacg gctgatgtag atattttata
     6841 ctttcaaaat gtttaaatgt gattatttat ttttgaaaaa tagatcacca gcccgactga
     6901 aagtgcttat agaatgataa taagtcgcct gccgaaaaca gcgaaaaata gcggtgttat
     6961 gcggagataa tctgacgcga tgcgaaagta tattgcatac ttattttcaa caatttagca
     7021 gagtattttt ataagtgtga tataatagaa gtataatttg ttctgatagt ttattttatg
     7081 gagaagtaga tttttagaat gcggagggtt caatatggtt gagtttataa agtctaagaa
     7141 agaaatgagt gaggaggata ttaaagcaaa tttcatcact cctgctattg tatccaaagg
     7201 atggaaaaat ggtgagcata tcgcttacga agaatacttc actgatggtc gaattgaagt
     7261 tagaggagat aaggctcatc gtaaagaagg aaaaaaatca gactattcac tgtattacca
     7321 atttggaact cgaattgcaa ttgttgaggc aaaggataat aaacacagcg ttcgagcagg
     7381 attacaacaa gctattgaat atggagagat tttagatgtt ccatttgttt attcttcgaa
     7441 tggtgatggc tttattgaac acgaccgtat cacgagagaa gaacgtgagc tggagttaga
     7501 cgaattccct actcgtgaag aattattttc tcgtatgacg aaggaaaaag gattgacgta
     7561 cgaaattaca gaagctatct caactccata ctatacagac gccttctcaa tgaaaacgcc
     7621 acgctattat cagcaaatag ctatcaaccg tactattgaa acagttgcca gaggacaaaa
     7681 acgagtaatg tttgtgatgg caacaggaac ggggaaaacg ttcatggctt ttcaaattat
     7741 tcatcgcctt cgaaaagctg gtttggctaa acgagtttta ttcttagcgg atagaaacat
     7801 cttagtagac caaacgatgg ctgaagactt taggccattc gaaaaggtaa tgacgaaaat
     7861 tacaccaaaa cttttgactg ctcctgaaaa attaaattct tttgaaattt atctagggct
     7921 ttatcagcaa ctaactggtg aagatggaac tgaaacacat tatcaaaaat ttgacaaaga
     7981 cttctttgat ttaatcgtaa ttgatgaagc gcaccgtggt tcagctaagg aaaacagtaa
     8041 ctggcgtaag ataattgatt atttcagttc tgcgacacag attgggatga ccgctactcc
     8101 taaagaaacc aagaatgctt ccaatacgga atactttggt gagccaatct atacttatag
     8161 tttaaaacag ggaatcgagg atggtttttt ggctccatat cgtgttatga gagttaattt
     8221 agatgtagat gtggatggtt atcgtccaga aactggaaaa gttgatgcta acggacaatt
     8281 aatagaagat aggtactacg gcaggaaaga ttttgataaa accattgtca ttgatgatag
     8341 aacgcaaaga gttgccaagt ttgtttctga ttatatgaag caaaacaatg cacgatttga
     8401 taaaacaatt gttttttgtg ttgatattga ccatgccgag cgaatgcgtg ctgcacttgt
     8461 aaaagagaat ctagacttag tccaagaaga ctatcgttat gtcatgcaag taactggtga
     8521 caacgctgaa ggaaaagctc aactggataa ctttatggat gtcaattcta attttcccgc
     8581 tattgtaaca acgtctaaat tattaacgac aggagttaat gctaaaacat gtcgtttgat
     8641 tgttttagac tctaatatcc aatccatgac tgaatttaaa caaattattg gtcgtggcac
     8701 acgtctttat cctcaaaagg ggaaagaatt ttttacgatt attgattttc gaaatgttac
     8761 caatttgttt gctgaccctg attttgatgg tgatccagtg aaggtgctgg aaacaggtgc
     8821 gaaaacagtc agtggttcta cgcccggttt cgtaagtgag gaaggtgacc cagtagaaaa
     8881 atatatcgtt acagacaagc aggttaccat tcttaattct actgttcaag tattggatga
     8941 aaacgggaaa ctgattaccg aaagcctgac cgactacact cggaagaata tcttaggtag
     9001 ctacgccact ttgaacgatt ttatcacagt ttggcatacg gcggataaaa agaagcttat
     9061 cttagacgaa ctttataaaa aaggagttta tctagatgct attcgagagt cggagggaat
     9121 atcagaacaa gaaatcgatg attttgattt actcctaaaa cttgcctatg gtcaaaaaga
     9181 attaaccaaa acggaacgta tcaataagct caaacaaagc ggatatttat ataaatatag
     9241 tgaggaagcg cgtgctgttt tggaaatttt actgaacaaa tacatggata aaggtattgg
     9301 agaactcgaa agcattgaaa cattaaaact tccagaattt cagatatatg gtggaacctt
     9361 caaaatcatc aatacttatt ttggagataa aaaacgatat ttacaagcaa ttaaagaatt
     9421 ggagcaagag ctatttacag tagcttaatg aaaggaaagt atgtcaatta catcatttgt
     9481 aaaaagaatt caagatatca ctcgaaacga tgctggtgtt aatggtgatg ctcaacgtat
     9541 tgagcaaatg tcttggttat tattcttaaa aatttatgat agccgtgaaa tggtttggga
     9601 attagaagaa gacgagtatg agtcaattat cccagaggaa ttaaaatggc gaaattgggc
     9661 tcatgctcaa aatggggaac gggtattgac aggcgatgaa ttacttgatt ttgtcaataa
     9721 caagttattc aaagagttga aagagcttga aataacttca aatatgccta ttcgaaaaac
     9781 gattgttaaa tcagcttttg aagatgcgaa caactatatg aaaaatggcg tcttgttacg
     9841 ccaagtcatc aatgctattg atgaagttga tttcaatagc cctgaagatc gtcattcgtt
     9901 taatgatatt tacgaaaaaa ttcttaaaga tattcaaaat gctgggaact caggagaatt
     9961 ttatacgcca cgtgcagcga ctgattttat tgccgaagtt cttgacccaa aacttggaga
    10021 atcaatggca gaccttgctt gcggaacagg aggcttcttg acttcgactc tgaaccgttt
    10081 aagtagtcaa cgtaaaacta gtgaagatac caaaaaatat aatacagctg tttttggtat
    10141 tgaaaagaaa gcatttcctc atcttttagc agttacaaat ctgtttcttc acgaaattga
    10201 tgaccctaaa attgttcatg gaaatacttt ggagaaaaat gttcgtgaat atacgaatga
    10261 tgaaaaattt gacattatta tgatgaatcc accttttgga gggtcagaat tagaaacaat
    10321 aaaaaataac tttccagcag aattacggag ttctgaaaca gctgatttat ttatggctgt
    10381 cattatgtat cgtttgaaag aaaatggtcg tgttggagtt attttacctg atggttttct
    10441 atttggtgaa ggtgtaaaaa ctcgcttgaa acaaaaactg gtagatgagt tcaacttgca
    10501 tacgattatt aggttgcctc atagtgtctt tgcaccgtat acaggaatcc atacgaacat
    10561 tcttttcttt gataaaacaa agaaaacaga agaaacttgg ttttatcgtt tagatatgcc
    10621 agatggttat aaaaatttct cgaaaactaa gccgatgaag tcagaacact tcaatcctgt
    10681 tcgtgactgg tgggaaaatc gtgaagagat tctggaaggt aagttctaca aatctaaatc
    10741 atttacacct agtgaattgg ctgagttgaa ttataattta gaccagtgtg gttttccaaa
    10801 agaggaagag gaaatcttaa atccctttga gttgattcag aattatcaag cggaaagagc
    10861 aactttaaat cataagattg ataatgtatt agctgatatt cttccgctcg atcagggatt
    10921 caaaaatcga caagcacaaa caaaacagtc gccatcatca tttattgaga taatatagta
    10981 gattgaaata agatgtaaac aaatcgatta ggaaagttaa attagtttct agaaattttt
    11041 agcagatgta gtgtactatt ctagtctcaa tttactatgg cttcaaatat atctttcgaa
    11101 aaaatattta cagatgtgta attttgaagc ttgtaaaagt tagtaaactt gtagatttcg
    11161 atttgaagta acttgttttc ttgcccgata ttgtttttga aattgaattt ttccatagtg
    11221 actccttgat tttcttctac acgtctgatg ataaatctaa ttcgcaaaag agtcaagagg
    11281 atttttcgaa aaataaatag cgaccgaaat cgctatttta agggttatag gtatttgatg
    11341 gcttagactg ctgtgtgact gtttacccac aggcaatctt tcttctatat tagtattagt
    11401 aaaggtctaa ataattatca atttcccatt gtgaaacgaa ggttgcataa cttgcccatt
    11461 cgattcgttt ggcttcaagg aagctagtgt agatgtgatc tccgagagca gctttaacca
    11521 cttcatcttc tgtcaaagct ttcaaagcgt tgtgaagagt tgatggaagg tctgtaatac
    11581 cagcttcctt gcgctcttct gctgtcatga tgtagatatt ttcttcgata ggagctggtg
    11641 cttcgatttt attttcaata ccatacaaac caacttccaa aagaacagcc atagcaacgt
    11701 aagggttcgc cattggatcc actgaacgca actcaagacg agttcccata ccacgtgaag
    11761 caggtacgcg cacaagtggc gaacggttac gaccagccca agcaatgtaa acaggcgctt
    11821 cataacctgg aaccaaacgt ttgtatgagt taactgttgg gttcatgatg gcagtatagt
    11881 tgtaagcatg cttgatcaaa ccgcctagga aatggtaagc tgtttctgac aactgcattc
    11941 cttttggatc atttggatca aagaaggcgt tatttccttc tgcatcaaac aaggacatat
    12001 tacagtgcat acctgagcca gcaataccaa attttggctt cgccataaat gttgcgtaaa
    12061 gtccgtgttt gcgagcaatg gttttaacaa caagtttaaa gatttgaatc ttatcacaag
    12121 cacggagaac ttcatcgtac ttaaagtcaa tctcatgctg tccaaccgca acctcgtggt
    12181 gactcgcttc tacttcaaat cccattttgg tcaagacatt cacaatctca cgacgtgtgt
    12241 tgtccgcaag gtcagtaggt gccaaatcaa agtagccacc cttgtcattc acttcaagtg
    12301 ttgggtcccc attttcatcc aacttaaata ggaagaattc tggctctgga ccaaggttga
    12361 aggatttgaa tccaacttct tccatgtgac gaagagctcg tttcaaatta ccacgagggt
    12421 cacccgcaaa tggttcacct tctgttgtat agacatcaca gatcagacct gcaacacttc
    12481 cattttcatc tccccaaggg aagactgtcc atgtatccaa gtccgggtac aagtacatat
    12541 ccgactcatt gatacgtaca aaaccttcaa tagaagatcc atcaaacata accttgttcg
    12601 ataagacctt atctaactgt tcatctgtag caggaatttc gacgtttttc atggttccca
    12661 aaatatctga gaacataaga cgaataaagg taacattttt ttccttgact tcacgacgaa
    12721 tatctgcagc tgtgattggc ataagttttc tccttaatct atgactactt gcggttgcct
    12781 aaccgcgacc aaaaggtgac tgtactgaag caaaacgccc ctgttggagg agttcattgt
    12841 gaagtgcacg acgtacttca gtctgactaa ccgctttctt ggatttcgct tcacgttcag
    12901 catatttttt cttaatggca gcgatattat aaccttcaga gatataatct ttgatttcaa
    12961 gcagacgatc catgtcattc aaggaataca tgcgacgatt tccttcgttt cgatcgggct
    13021 tgatcaactc ttgatcttca taataacgaa tctgacgcgc cgataaatcg gtcaacttca
    13081 taacactgcc gataggaaaa acagccatat ttcggcgaaa ttctttttcc ttcatttaca
    13141 atttccttct ttctgtctat tatagtctaa aaaaagacaa acgtcaattg ataatgttat
    13201 aaaatgtaac attatttttc ttttttctct aaaaagagac gaatacgatc aatatcgtaa
    13261 tttacaataa ttgcgacaaa aactcccata aacgtttctg atacacgcac aaacacgtac
    13321 gaaattgtct caccacttgg aattgatagg gtaatgatta acatagctgc tacaccacca
    13381 ataacccctg ctttgttatt catggctaca tttgtcataa tggttaacat ggtgcagatt
    13441 ggaacaacta ccaaggtcac ccaaaaggct tcgtggaaaa aggtatttaa taagaagaag
    13501 accaaggcat agagtccacc gatactattt cctagaatac gcgaagtccc aaaatgaaca
    13561 ctcttatcaa aactctccct caggctaaaa acggctgtca aagcaccaat ttgaagacct
    13621 ttccagccaa aaaagccaaa aatcaagaga actagaaaaa cagcaatacc tgttttaaag
    13681 gttcgcatac caagtttgaa ctgggattta tcgaatttat attttttaaa ataactcata
    13741 atctcaactt tctatttcca ttttatcata aatcggtgat ttttatgagt aatagttgag
    13801 aggaagcgtt tttattttaa gcaaaagaaa agaggaactt tcatccctct cttctttgat
    13861 ttgtttataa aatcttattt ttctgtcaag gctgcaagtc ctggaagaac cttaccttca
    13921 agaagttcca ttgatgctcc accacccgta ctaatccatg agaacttgtc tgcacggcca
    13981 aggttaatcg ctgcggcagc tgagtcacca ccaccgatga ttgatttaac tcctggttgt
    14041 ttcacgatag cgtccatcac accgattgta ccagcttgga aatctgggtt ttcaaataca
    14101 cccataggtc cgttccatac aactgttttg gcaccagtca aagcttcgtc aaatttggcg
    14161 atagattttg gaccgatgtc aagaccaagg aagccttcag aaactgcttc accttcagtg
    14221 tcacgcactt cagtgtaacc agcaaatgcg ttagcttctt ttgagtcaac tggcaagatc
    14281 aatttaccat ttgctttttc aagaagagct ttcgcaacat ccaatttgtc ttcttctaca
    14341 agtgagttac cgatttcgat accttgtgct ttgtagaatg tgtaagtcat cccaccaccg
    14401 ataaggactt tatcagcttt ttcaagcaag ttttcgataa caccgatctt gtctgaaact
    14461 tttgaaccac caaggatagc cacgaatgga cgttctggag tttcaactgc ttcttggatg
    14521 taggcaattt cgttttcaag aaggaaacca gcaactgctt tttcaacgtt tgctgagata
    14581 ccaacgttag atgcgtgtgc acggtgagct gtaccgaatg catcgtttac gaagatacca
    14641 tctccaagtg atgcccagta tttaccaagt tcaggatcgt ttttagattc tttcttgccg
    14701 tcaacatctt cgtaacgagt gttttcaacc aagagaactt gtccatcttc aagagcgttg
    14761 attgccgctt ccaattcagc accacgagtg acacctggga aaacaacatc ttgaccaagt
    14821 tttgctgcca agtctgctgc tacaggagca agtgatttac cagctttatc agcttcttct
    14881 ttcacacgtc caaggtgaga gaaaagaatt gcacgtccac cttgttcgat gatgtactta
    14941 atagttggaa gagctgctgt gatacggtta tcgttagtga ttacgccatc tttcaatggt
    15001 acgttgaagt caacacgaac gaggactttt ttacctttca agtcaacgtc tttaacagta
    15061 agttttgcca tgttacaaaa actcctttat ttattttatt cgaaactatt atatcacact
    15121 ttggaaatat aaggaaagat ttcacaagat ttttcgatat ttaatcttta tcttctcttt
    15181 tccgtctcaa ggtcaaggct aaactagcaa gaccgaggct ggctaagcct gctattaggg
    15241 cttcattagc atcagctgtt cctgtatttg gcaattgttt gcttgcttct tctgatttaa
    15301 ctgctgtatt ttgagctggt ttttcctgtg tagctactac tgctggtact gtttttactt
    15361 ttgttccaat ttcaacaatt tctggaatcg cttcttggat gacttctgtt gaacgaagac
    15421 gacgctgacc gttttcatca acttcaaaga catgtcttaa cagtccatct cgtccctgta
    15481 taatgactcg ttgttcccca actagcatct cagcattttc atgctcttga cgatgaaagg
    15541 caaccttttc ctcttgaact tccaatttag gagccttttg ttgatcagaa gccggttgat
    15601 aagtaggttt tggaaggact ttgttttgtg gtgctggttt agcaggttgt ggtttttcag
    15661 cagattcata aacaaaggca taatgagtaa agtgaggtgc tgtaaagata acatgactat
    15721 ccgtttgttc aaaagccaat tctactgcct ctttgccttc aggtaagaaa aatactttct
    15781 taactttctt atctttttca attgggattt tcacaataga agcataagag agatcaacat
    15841 cttgaccttt ttcatccaaa ccttctattt caaagacatg agcatcttct ccagcaaagt
    15901 atttcttctc ttcagcactt gcttgaacac gctctacttt caaacccttg atgacagtct
    15961 tctctttatt tgagaagtgt acttcaacac ctgttttact atcagaaaag actgctgact
    16021 tgtcttcttt caataaagca accagatctt ttagactctg tttcgctgtt gcaagctctt
    16081 ctggactcaa atctactttt tcaaccaagg ccttgttttt ctcaagaagc ggagctaggg
    16141 cagaacctga aggatggttt ggtttggcag ccaagagttc ttgagcctca cctgttaagc
    16201 gatcaagctc tgtcttttct tccgtaaatt tctcttgacc attcagagct ttatgagctt
    16261 ctgtcaattt attaagtcgg tcattgactt gatcttgggt gctagtttca tggtctttca
    16321 acacttgttc ggccgcttca attgctttca agaaggcttc ttttacttct ggtgaagcaa
    16381 agttatagac caccttgttc ttagcagctt caacttctgc taatttttgt ttgaggtact
    16441 catcgttcaa tgctgctttt ggagatacca aaacatcaaa gttgacttca tgaccttggt
    16501 aacgaagcgt caaggtttga cgaccagtct tttgagcatc gtaaccagaa atttcaactc
    16561 cctcatcagt aaaggaatgt tcttccatgg tgtcattgct ataagccact gcaaagcgtc
    16621 cttcagacaa gtctaagtta tcaccaacta ggtaatcttt tttcggttcc tgacttactt
    16681 caattcccaa aatagttttc ggacttgctt catcttggcc agtgacagtc actgacaaat
    16741 tagcatttac tggttgtccc aaatattgga gagtaagatt ctgttctccc ttatgatgcg
    16801 tatcaaaacc tgatactgat acacctgcgt gagttaggcg aatgagttcg tcctcagttc
    16861 ctccttcata ctgaactcga agaacaccac ctctaaggtc caaatcctcc ccttcggcgt
    16921 agcttgtttt cttaggtcct gtttctaggc tgactgactt gattcttctg tcatcttttg
    16981 gaacggaaac tgctaggaca ttactaattt ccttgcctgg caactgggta cgataataaa
    17041 gaagaccaga ttgatttgtc aaatccaatg gtgcacttgc taggtctcct ccaacttcgc
    17101 tcttcaaggt tgcgagcgga gtttgagaat ttggattatc ataaacggta atagttgctc
    17161 cagccggtac atctgcaaag ccaacttgta ccttgttatt gcctagagaa cgggctgcag
    17221 ccttggccat cggaatattg acactctcag tatcaagctt ttcatacatt ttccagttat
    17281 agatacgaat agccttccat ggagttccat tgtcagaagt gacaacattc aagcgccagt
    17341 cttgagcagt gattggttta tcaagagtga tatctgtcac gtgtgctttg ttaccacgga
    17401 cttccttagc tagcttccac tcaccatctg catctttata ataaaggtca aagtctttag
    17461 tgttcatcaa gccatcgtta acagactcac caccagctcc tgcatgatcc atgacccatc
    17521 taacaacagt acgtggcttg gtcaaacgaa tatccacact accactcaac tgagctgaag
    17581 accatttatc tgacaagcta gtaatggtac cgttcaacat accttcaata ccttctccac
    17641 cttcagtctt agggaaagta ctatcaataa ctgttgcacc tggaacgata ttttcagcta
    17701 gtggttttgg taggctggta tcttttacag tcatacccca atcaaaggtt gtggttgcag
    17761 cttctgaacg aactccattt ttaccgactg ctacaacctt cagttcttga gttgtaccct
    17821 gagcacttgc tgagcggcta acttttggta gataaatagt tgtagaagat gagccagtta
    17881 gtaatttcca gctgtctcca tctttttcat aaacttcata gaaatctgca tccttgttgc
    17941 ctttaaattg cacaactgct tccgcttctt gggcattttt aagagattgt ttcactacag
    18001 aaaagcttgt cggcgattgt ggctcttggt gattgtccga gatagttaat tgtccgaggt
    18061 tgaactgata atcttttaca gcaccttcat gctcaaaaaa tagtttgact gcatagatgg
    18121 ttttacctgc tagtgagctg agagcaaatt cttcatttgt ccagttgtca gaaagggtta
    18181 gctctttcca tgcatctgca tcatcgaatt tgtagtctgg agttgtagag aatgccatat
    18241 aaactttaga accttttcct cccttgtggg caacacgaag tttggtcttc tcagttactt
    18301 ctaacttagt agaataaagt ctcacatcct gatctgtctt accggctaca tcaccagaga
    18361 atttaaggga atttccgcca ttataggcat ctgtaaaatc atattctgca cgaagttttt
    18421 cccctgttga agtctgccac cagcgccatg ttggaagaac acctgatact gaacgataat
    18481 tccactcaga atccttagaa accttaccat ctacgaacca ttttttacca tgacctgtat
    18541 taaaagaagt agtaaaagta ttacctaccg ctggcgtacg gtccgcaact aggttagcaa
    18601 taccatacca atctttgtca cctggttttt ggccagtagg gtctccttga taacctgtaa
    18661 agaagatatc ttcattttta tgataatctt caccagtttt tcctaaactt gtaatggtat
    18721 ctggggcaaa taaaccaaga gaaaggcgca atttcccatt ttcgtctaaa atgtcattcc
    18781 acttaacctt tgtcttgtag gaaccaccct gttgcaattc caaacctgca aatacatcat
    18841 aaggattacg accaatccag ttggcagttg caatagtgta atcattttta gccttatccc
    18901 agttaaagtt agcaaagaag ttatctgccg gaaccttatc tccttctggt tgcatgaatt
    18961 ggtagttgta ttctcccaaa ccatcttgat gataacgtcc atagttatag gtcatggcat
    19021 cgtaccaaga atacttgatt ggatggttta ccttagcagc atattccttg ctatagagca
    19081 taaactggcg catcttttct ccaagaggtt taaccaaatc tccagttgtt tcttggttga
    19141 tgaaatagcc atcatagcca taatacttgg ccatgtctac caatttacgg gcaattggga
    19201 agctaccatc tgcgtcttgc ttcaaagctt cagcaaatct ttcttgatct gcaatactat
    19261 tagaccagtt gaagaagagt gtaccgtata caggaacccc gttacggtga cctgcatcaa
    19321 taacgtcagg agttggtacg agaccttccc agaagaccat tgaatctaga tattgccaat
    19381 agtcaaaagc ataggccttg aactcttctc caccaacaga agcatggtct tttgctttag
    19441 aattggtgtt tgataaggct tgaacttttg cttccttgct agctttttca ttgactaaat
    19501 gacctgtccg acgtgaagcg aggacaacag atccgcggtt aatagcatca tcttcacgag
    19561 cacctggttc ccattttaac aattcttccc aagaattaaa tttgatttcc tttggtttta
    19621 atgttttttc tgtattttta gggacatctg gctggacttc tttttcagtc ttattagctt
    19681 ctgctgctgg tttagactca tccccttggt tagttgcttc gggctttgct tctgtttcct
    19741 tgtcagactt aggttttgct tctgcagatg gtgtttctgc aaccacctca cttgcttttt
    19801 cctctggttt agctgcgcta gctgcttctg cagtttcaga tgctatcgct actccttctg
    19861 ccttttctag cttgttttct ctagcatgtt ccccttcatt ctgcttatca gcttcattgg
    19921 tcgaatgctc actctctcct gaaacaagct ctggattagc tccgctattt tcaggaactg
    19981 cagtttcttc agccaaggct ggaccagcaa ataaaacagc accaatcatc agcgagcagg
    20041 ctcctactga taacttacga atactgtaac gacaacgtct ttcaaaaaat ggattcttca
    20101 ttttctcctc ctaaaagatt gattttgttg ttttcaagaa agcgctttat attctgtagt
    20161 tttttatcaa actctagaac catgataatc acatttttat cctaaaacat ttttagacaa
    20221 aaaacaataa ctgtttgcac aaatctaaaa taaggttaaa aactcttaaa aataatacac
    20281 ttatcaatta taattttctt ttacaaactt gacattaaca cttgttagat ttacttttat
    20341 cctttaaaat agaataggag atattccgcg attatttttc ggaggaaaaa gaaatgtcca
    20401 ttaattggca ggaaatttta tttcactttt taggtggtct ggggctattc ttatatagca
    20461 tcaagaccat gggagacggt ttgcaacaag ctgctggaga tcgccttcgt ttttacattg
    20521 acaaatatac tagtaatcct ttctttggag ttctggttgg tattgggatg actgctctaa
    20581 ttcagtctag ttctggtgta acagttatca cagtcggcct ggtcagtgcc ggtctcttaa
    20641 ccttacgtca ggctatcggg attgtcatgg gtgctaatat tgggacaact gtcacatcct
    20701 ttctcatcgg ttttaaatta ggtaactatg ccctacctat gctctttatc ggtgccgtct
    20761 gtctcttttt tacaaaaaat cggacagtca ataatatcgg acgcatcctc tttggtttcg
    20821 gtggtatctt ttttgccctc aatctcatga gcggcgcaat ggctccactc aaggatttac
    20881 aggtctttaa ggactatatg attgagctaa gtaagaatcc tgttttgggt gtctttgtcg
    20941 gtaccggctt gaccttgcta attcaagctt cttcggctac cattgggatt ttacaaaacc
    21001 tctacgccgg caatctaatt gacctacagg gagctttgcc agttctattt ggtgacaata
    21061 tcgggacaac cattacagcc atcattgcct ctttaggggc taatattgca gctaaacggg
    21121 tagcaggagc tcatgttgcc ttcaacgtta tcggaacagt cgtctgcgtt atttttctag
    21181 ttccttttac tgtcctgatt cattggtttg aagctacgct aaatctagca ccggaaatga
    21241 ccatcgcctt tgctcacgga acctttaata ttaccaacac cattgtccaa tttccattta
    21301 tcggagctct ggcttacttt gtaaccaaga ttattcctgg agaggacgag gttgtcaaat
    21361 acgaaccctt atatcttgat gaacatttca tcaaacaggc cccatctatc gctctaggaa
    21421 atgctaagaa agagctcttg cacttaggaa actacgctgc taaagccttt gacctttcct
    21481 ataagtacat cattgatttg gatgaaaaag ttgctgaaaa agggcataaa accgaagaag
    21541 caattaacac catcgatgag caattaacac gttatctcat tgccctttca agcgaagctc
    21601 tcagccaaaa agaaagtgaa gtgcttacca atatccttga ttcctcccgt gatttggaac
    21661 ggattggaga ccacacggag gctctactca atctgactga ctatcttcaa cggaaaaatg
    21721 ttgaattttc tgatgccgcc ttgaaagaat tagaggaagt ttaccgccaa actagtgact
    21781 ttatcaaaga tgctctggat agtgtggaaa acaatgatat tgaaaaagca cgcagtcttg
    21841 tagaacgtca tgaagcaatc aataagatag aacgtgttct cagaaaaacc cacatcaaac
    21901 gcctcaacaa aggcgaatgt tcaacacaag ctggggtcaa ctttatcgac atcatctcac
    21961 actacactcg tgtatcagac cacgctatga accttgctga aaaggttttt gcagaacaaa
    22021 tctaagaacc aagaagctat ccatcataat tggatggctt tttacttttt cctaagcaag
    22081 actaggctga atgaaactga aagagtattc tgcagatata tagtatattg aaactagaat
    22141 agtacacctc tatttctaaa acattgttag aaatcgattt gactgtcctg atcgatttgt
    22201 cc
//
LOCUS       DBERDS010000030        21747 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.030, whole genome shotgun sequence.
ACCESSION   DBERDS010000030 DBERDS010000000
VERSION     DBERDS010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.030"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..242)
                     /locus_tag="ACL73E_001329"
     CDS             complement(<1..242)
                     /locus_tag="ACL73E_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HGS0801293.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIFID"
     gene            complement(246..464)
                     /locus_tag="ACL73E_001330"
     CDS             complement(246..464)
                     /locus_tag="ACL73E_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0801294.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(1202..2833)
                     /gene="rlmD"
                     /locus_tag="ACL73E_001331"
     CDS             complement(1202..2833)
                     /gene="rlmD"
                     /locus_tag="ACL73E_001331"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS0801295.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2907..3881)
                     /locus_tag="ACL73E_001332"
     CDS             complement(2907..3881)
                     /locus_tag="ACL73E_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGS0801296.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVYAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3955..4569)
                     /gene="pmp23"
                     /locus_tag="ACL73E_001333"
     CDS             complement(3955..4569)
                     /gene="pmp23"
                     /locus_tag="ACL73E_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGS0801297.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4569..5543)
                     /locus_tag="ACL73E_001334"
     CDS             complement(4569..5543)
                     /locus_tag="ACL73E_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGS0801298.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5551..6807)
                     /gene="glyA"
                     /locus_tag="ACL73E_001335"
     CDS             complement(5551..6807)
                     /gene="glyA"
                     /locus_tag="ACL73E_001335"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGS0801299.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(6869..7300)
                     /locus_tag="ACL73E_001336"
     CDS             complement(6869..7300)
                     /locus_tag="ACL73E_001336"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801300.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7302..7901)
                     /locus_tag="ACL73E_001337"
     CDS             complement(7302..7901)
                     /locus_tag="ACL73E_001337"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGS0801301.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7888..8727)
                     /gene="prmC"
                     /locus_tag="ACL73E_001338"
     CDS             complement(7888..8727)
                     /gene="prmC"
                     /locus_tag="ACL73E_001338"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGS0801302.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(8727..9806)
                     /gene="prfA"
                     /locus_tag="ACL73E_001339"
     CDS             complement(8727..9806)
                     /gene="prfA"
                     /locus_tag="ACL73E_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGS0801303.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9816..10295)
                     /locus_tag="ACL73E_001340"
     CDS             complement(9816..10295)
                     /locus_tag="ACL73E_001340"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801304.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(10285..10884)
                     /locus_tag="ACL73E_001341"
     CDS             complement(10285..10884)
                     /locus_tag="ACL73E_001341"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGS0801305.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALTIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            11007..11189
                     /locus_tag="ACL73E_001342"
     CDS             11007..11189
                     /locus_tag="ACL73E_001342"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGS0801306.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11326..12699
                     /gene="mnmE"
                     /locus_tag="ACL73E_001343"
     CDS             11326..12699
                     /gene="mnmE"
                     /locus_tag="ACL73E_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGS0801307.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEEVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12746..13681)
                     /gene="dapA"
                     /locus_tag="ACL73E_001344"
     CDS             complement(12746..13681)
                     /gene="dapA"
                     /locus_tag="ACL73E_001344"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGS0801308.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     YPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13737..14813)
                     /locus_tag="ACL73E_001345"
     CDS             complement(13737..14813)
                     /locus_tag="ACL73E_001345"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGS0801309.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIVACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15399..15471)
                     /locus_tag="ACL73E_001346"
     tRNA            complement(15399..15471)
                     /locus_tag="ACL73E_001346"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15436..15438),aa:Thr,seq:ggt)
     gene            complement(15571..16080)
                     /locus_tag="ACL73E_001347"
     CDS             complement(15571..16080)
                     /locus_tag="ACL73E_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGS0801310.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(16078..16174)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            16203..16634
                     /locus_tag="ACL73E_001348"
     CDS             16203..16634
                     /locus_tag="ACL73E_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGS0801311.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            16716..17093
                     /gene="mscL"
                     /locus_tag="ACL73E_001349"
     CDS             16716..17093
                     /gene="mscL"
                     /locus_tag="ACL73E_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGS0801312.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(17135..18229)
                     /gene="hemH"
                     /locus_tag="ACL73E_001350"
     CDS             complement(17135..18229)
                     /gene="hemH"
                     /locus_tag="ACL73E_001350"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGS0801313.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVSISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            18384..19607
                     /gene="pepT"
                     /locus_tag="ACL73E_001351"
     CDS             18384..19607
                     /gene="pepT"
                     /locus_tag="ACL73E_001351"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGS0801314.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTTIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(19643..20293)
                     /locus_tag="ACL73E_001352"
                     /pseudo
     CDS             complement(19643..20293)
                     /locus_tag="ACL73E_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            20294..20458
                     /locus_tag="ACL73E_001353"
                     /pseudo
     CDS             20294..20458
                     /locus_tag="ACL73E_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(20729..21741)
                     /locus_tag="ACL73E_001354"
                     /pseudo
     CDS             complement(20729..21741)
                     /locus_tag="ACL73E_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1,RefSeq:WP_007521835.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6303 a         4530 c         4000 g         6914 t
ORIGIN      
        1 tcatcaataa aaatttgttt gctaatatct ctttcttctg attttgtttc aaggattatt
       61 gctacatcat tcatattttt aggtaaatac caaccatctg gcttatctga atatcccttg
      121 aagcctaatt gattaaaagt agttatttga ccagtacctt gattgatgtt ttcttcaact
      181 tcattaaagc ctaatacttc tcttgcataa tccctaactt gatcttctgt cctcaaagtc
      241 attttctatt cctcatcact aaaattatct tcaaaactaa taatatcatt aggagtgcaa
      301 gataaagcct tacatattct ttctaaattc ttaaatgtaa ttggtttatc ctttcccatt
      361 tgtgccataa catttgttgt aagtcctgcc atagctatta catctgtttt ctttagtcct
      421 ttttttgcta actgtatcca taatggttta tagttaagtg ccataatatc cctctttttt
      481 tcttcattag atttatttaa ttatagcata aatattgatt tcattcaatc ttacattgat
      541 ttagtgattt gttttagaga atttgttgtg ttattccgtc cttattttgc cataaattgt
      601 tttaagtggg acctcttatc cttaccattt ttacctccta attttgagta taaaaaagac
      661 gatagagttt ttaatttcta tcgtctgaga tttacatatt aaattttcat cacaaaataa
      721 gactctttaa agaatcttta aattcattgg tatgctaatt acaatatcca ttattaaaat
      781 ggatactata agcagcacac caactattta ttttttgagt tttaaacttt ggtagaagtc
      841 ttgaactcct tatatttaca taactatttg cctctataac tattatgaca cgaaaccaac
      901 aagcaagttc aagcacctcc atatctttat tcaaatgagg actaagatat tcacaaactt
      961 tatcataaac ctctttatct tttttcataa aaggggcata caacttagca aatttatcct
     1021 aaaatttttt gttgccttta tcaatcattt caacgctcct ttaaatataa aaatgatcct
     1081 atcaatcttt atattgagcc tattttctaa ttgatacctt gcaagaaagg aataatagct
     1141 gttcctatac caagtaggaa tgtaataaat gcagaaagtc atatactgtc attcttttct
     1201 attaaatcat tttgaagtgt ctcaaagcat ccatgatggc ttcttctttt tcaggtgtac
     1261 actgtggaat aatttgttta tcctttttag acttgttgta atgttctcgt aattctattc
     1321 cacatttctt ttttatctgt gcaatatata atgtcgaaac ttttaattca aatttattcc
     1381 aaacatattc tttgatttga gcatatgttg ctttgctctc cgcacttgtc aaattcatct
     1441 catccagctc aatttcaaca cttatgtgct tatcgacatc gagtttggac aaaagtgcta
     1501 ccgtctcgac gtgatgcgtt tgaggaaata gatccaccgg ctggactttc ttcaattcat
     1561 atcccaattc ttggtagagt ttgatatcac gcgccatggt tgcgacattg caggagatat
     1621 aggcgatgcg atcggctcct gtttgggcgc ttgctttgat aaagctttct gtcaagccct
     1681 tgcgtggagg atcaaccaag ataacggttg gttgaatccc atctttaagc caattcttca
     1741 tagcattttc agctgtgtca cagacataat gggcgtttga aatattgttc agctgagcat
     1801 tttttttact attctcaacc gcttctggaa tcagttcaac accgtagact tctttgacat
     1861 gcttggcgac tgataaacca atggttccaa taccagaata agcatcaata accacgtcat
     1921 ctttttttaa ctctgcaaag tcaatggctg tttgatagag tttctccgcc atttcagtat
     1981 tgacttggta aaaggctggg ccagcgattt ggaagtcatt tcccaacatc tggtccgtaa
     2041 tatagtcttg accataaaga gtgcgccact ccttaccaaa aatcgcattg gtattctggt
     2101 cgttgatatt ttgcatgaca gacacaatct ctgggaactg cttgataact tgttcaatca
     2161 attggtcaac acgaaaaact tttggacgag ttgtcaccaa aacgaccatg atttgtcctg
     2221 aatagtgacc acgacgcacc acaagattcc gaatcaatcc agactgttcc ttttcgtcat
     2281 aaggttttaa atcaaaacga cggagcaggt ctcgaagagc tactacgact tggtcaatga
     2341 caggatcctg gataaagaaa tcttcaaggg gcatgaggtt gtgcgaattc ttacggaaaa
     2401 atcctgtttc caagacacca ttcactcgac gaacgggcac ctgcgcctta ttgcgatact
     2461 tgactggatg ttccatacca agcgtttcag caacttctac atctgcaatt ccagcaatct
     2521 tgtagagact gtccttgact tgcttggttt taaacttgag ctgttctgga taagaaaggt
     2581 gtcctaaatc cgcgattcct gaacgcaggt aagccaaatc tagatcttga ttacggtgtg
     2641 gtgactggac aaggtatttt tcaacttttc caaagccaat ctttttattg accttgagga
     2701 cacgcatgag aattttttca ctcggtaaag cattctctac aaaaaagacc aaaccatcta
     2761 ccttggcaac tcctgcccct tcatgggtca aatcaacaat ttcaacttct acaatatcat
     2821 ttttctttaa cattcttttc tctttctatt ggccgacaaa aaagacggca acgttacggt
     2881 taccatccat tataccatga aatttcttaa gaaccaaaac tcttgaagaa gttgacaagg
     2941 gcttgccaga gggagcttaa gaagttacca ccgtcctcta gcgccttatc cgcatcaaag
     3001 ttaaggttga tatttttaaa actgtcgcca gcttgtgata cgatgctttg tttaaggtca
     3061 tttagggttt tagtgaaatc tgcattgctg aggatatcac tctttgagag attcaaggca
     3121 aaattgatga tgatattgat ctggtttcct gttatgacct gatcaagttt gtaatttttt
     3181 aaggtatctt caacaatctt gcggatatct tcttctgtca gatttccctt gctttcttta
     3241 gctttggcga gtcctgactt gatatcagct agggcaacgt ttaatttatt agcatcatag
     3301 cctgatttgt ccttgttttc agcattgata tctgacaaag cctttagctc ttcttgagcc
     3361 aaatctttat tggcttgcgg caccttggct ccattagctt ctagcgaata gtagatccca
     3421 gccaaagcac tctcacctgt aactggaatg ggtgctgcta cagtgatttt ggcgtgttcc
     3481 acacccaaag ttacggctgc atttcggtac atatcctgag ttaccttagt gatgttttca
     3541 ggtgtttcaa tcttgacctc aagtggcgat ttgtcaccta gcttttgaat cttggctgat
     3601 gaatacaact gtaagctaga gtcattggcc acattcatga ttttagaata aacatcaggt
     3661 gtcatggtct taagttcttt ggtatctgtt gaggcattgt agcccagttt tttaagagtt
     3721 tgattttttt ggtcttcaga tagggaagaa cctaggacat attcaggttg gacataggtt
     3781 tcatcgataa ctttttgaac atctgttgct gcatagacgc tattcatagc tgttactgcc
     3841 cacaagatcg cagcgctagt cagaaagagt ttctttctca tagggaattt cctcctttac
     3901 ttctttagag taatatatct atcttaaaga aaacttataa caaaaacacc tggtctagcc
     3961 agatgttgaa aagagagtga aacatttgat gatgtaaagg ttaagtcgta cctgtctaga
     4021 ataataatag tttcctccat ttacatagag ttcagcaccg tgaaaaatgg aaatgggatg
     4081 aatataacta taagtctttc cagtcgtatt accaagcaag ggggcaacag tctcacgaga
     4141 gtactgtttg gctagagcca aggtattttc cttgccattt tgggcgataa aatcgatata
     4201 ggcaggtcca aaattatagg cttgaacagc tgtccagata tctacaccct tcttctgcgc
     4261 cagatagaga ttgcctgtca gagtttgaat gccttgccga atgctagagg cattatcatt
     4321 gatggtgttg gtggaaccac ttgcagactc actagactgc ataacatcgc cttcttttcc
     4381 ttttgtttca gtataaatca tagcaagcac aagctcttcg tttgctgggg tgtctttttc
     4441 actcaatatt tctcgcacca tgggttgata ggtcatgact tgtttgacat cttgatgaac
     4501 gcggtaagct ttatagccag caaaaaggaa gactgctagt acaagcactc ttcgaattcg
     4561 tttaaacatt atttactttg gatatcctcg atatttttga ttaagataga gtaggttcca
     4621 ttttcgtttt ggataaactc aacagactcg gcgtcttgat agacgttatt gggaacgatg
     4681 agctcaattc catttgataa ggagagtttt tggttttcaa atttctttaa ttggcgactg
     4741 gcatcaattt catcaaattg aacaggttct ggtacggctt ctttgacttg gtcaataaag
     4801 ctcaaacgag ccgtcagatt gttgtcaaaa aggtcattag ccaatttctc aggtgacaat
     4861 tcattgcttt cttctaggtt gttgaaaatc gctgatttga ccttggattg aaattgaaaa
     4921 tcatctgtgt taaaagattc agcaattctc tgggctgttt tttccagttc cttgatagat
     4981 tttttaggag aaatcttagg agcgacagca agaagattat ctgaaaaata gttcaaaaaa
     5041 gtcccgttgt acttgattcg tttttcaatc aggtgatact tgcgactctg aagattgacc
     5101 accaaggcct cgtcagcacc cgttccaaat ccaggcaggt tattctgagt cagcttgatt
     5161 ggattatcaa cttctcctcc gaggtgggtc aaggtctccc gcagggcaat tcgcaagaaa
     5221 gcgaaatgtt ctacaccttc tttagaaaat tgaacaaaaa tcaagtcatt ggtcttgaga
     5281 ttttcagaaa tgctaaactc ctctttccag agattagcca gcgttactga tgtctccaac
     5341 aaatcgtctg taatatgatt gaagaaggga ttttcttctt cgaaaatccc agtcttggct
     5401 tcatctgaat acacatgttc aattttttta cgtaggtatt cttcgatttt tggagtaata
     5461 ttgagaaact tatctgctaa gaacagctcg gtatcatccg gactgaactg gtgaataatg
     5521 gctttcttaa tataaatatc cataaaagtt ttagtcctcg tataatggga aggcatctgt
     5581 caattctttg actgcacttc tcacttcttc taatacagcc tcattttctg aattcttaag
     5641 ggttttaatg atgagttcag ccactttgcg actttcttct tcaccaaatc cacgtgcagt
     5701 aatagctgct gctccgatac gaatcccact tgtcttgaat ggcgacaagg tttcgtaagg
     5761 gattgaattt ttatttaggg taatattgac ttcatccagc aagttttgag caacttttcc
     5821 gttttctaca accttagtca catcaacaag gaagagatgg ttttcagttc cacctgaaat
     5881 aatacggaaa tcagggtctt gcaagaagac atctgccata gccttgctgt tcttaattac
     5941 attggcagca tattccttga aggctggatc caaaacttct ttgaaagaaa ctgctttagc
     6001 cgccacaaca tgctctaaag gaccgccctg aatacctggg aaaatagctg aattgatttt
     6061 tttagcaagt tcttcgtcat tggtcaaaat caaaccacca cgaggtccac gaagggtttt
     6121 gtgggtcgtt gttgttgtga tatgagcgta tggaactggg cttggatgaa ggccagccgc
     6181 aaccaaacca gcgatatggg ccatgtccac catgagcttc gcaccgacag catctgcgat
     6241 ttcacggaat tttgaaaaat cgataatttg agaatatgct gaagcaccag ctacaatcag
     6301 ttttggtttt acttcttggg cttgtttcaa gatagcatca aagtctaaga gttccgtttc
     6361 aggatcaaca ctataagaaa caaagttgta ggtttgacca gagaagctaa caggagcccc
     6421 atgagtcaaa tgaccacctg atgccaaatc cattcccata accgtatcac ctggctcaat
     6481 caaggacatg taagccgcac agttagcttg gcttcctgaa tgtggttgga cattggcaaa
     6541 tttagcaccg aaaatttctt ttgcgcgttc aatagcaaga gtctctacaa cgtctactac
     6601 atcagttcca ccataataac ggcgtcctgg gtaaccctcg gcatatttat ttgtcaagat
     6661 agacccttga gctgccataa cagccttgga aactacgttt tccgaagcaa ttaactcgat
     6721 attattttgt tggcgttctt cttctttggc aatagcattc cagagatcag catcatatgc
     6781 tttaaaatca tctttgtcaa aaatcatagg tcttctcctt tattgtgtga ctagtccatt
     6841 agtttgattt tacaataaga aaatcaaact aaaagatgcg aataaaccgt ttctgcattt
     6901 tatcacaagt atagccaact ttttcataaa atgcatgagc acccagacga tgattggcag
     6961 aatttaagcg gataaaccca taaccacatc ttttggcttc ttgttccaac ccttgtagta
     7021 aacttttacc gataccttga ccttgcgctt gaggtgaaac tgctaaagct aagatattaa
     7081 atcctgcttt ggaatagagt gattcgtaaa cttcagcgtg gacatatcca agtaagacat
     7141 gattagctgc atcctcatag ccaagtagga aatgatggga atcctgagac agtctagcta
     7201 gttggctagc cgtttcctct ggactaaaag tataacccaa agcctcttgg ttgatgtcac
     7261 atatcgcttt cacatctgtt tcttgcaaat ctcttagcat ttcaagcctc ctcaaaagaa
     7321 atctctggca accgagcaag aatatcttct cgtttaattg cgccttggcg taagattttc
     7381 accttgtctc cagacaaatc cacaatagtt gaatcctgtc cagttagaaa agcatcgtct
     7441 tccagaccca gaacctcttg gtcaaaatcc ttcagaattt gttcaaaggt tacaccactt
     7501 gcctgacctg agatattggc agacggccca atcaagggac ctgtctctcg aattaaatcc
     7561 agtgtgatag ggtgactggg catccgaaat ccaatagttg caaggtcaga atttacccaa
     7621 tagggaactc ggtcattggc ttcgagaata atggtcaagg gacctggcaa aaaggtctct
     7681 acaagttttt gtagataagc tggctgattc ttagaaaagt gcaagatatc ctctaaagag
     7741 gcaacattga gattgagcgc cttgtctcta ggacgacgtt tgagctggta aacatggtca
     7801 actgcttttt cgtctaaggc cttggcaaaa agaccataaa ccgtctctgt aggcagaatg
     7861 acagctccac cattttccaa ctcttgtcta atcctgtcca tcatcaacca cgaccatcct
     7921 atcttgacca aattggtcct tgagtgttcg aacttttttt tcaggaagat gttttctaaa
     7981 aagttcggga acactttgac cttgcttgta tccaatttca aggtaaatct taccaccatc
     8041 tttgagatag tcttttgcat cttccgcaat tctacggtaa atagctaggc catcctcgtc
     8101 tgcaaagaga gctagatgag gctccgaata caagacattc aagcctacct ctgactcatc
     8161 ttcacgagag atatagggtg gattggaaac aattatatca tatttttcag aaatttctgt
     8221 aaaacagtca gattttttaa aaaatatttg aagattttga tttttagcat tttcgctagc
     8281 taaatctaaa gcctcttgag aaacatctgc tgctgtcact gaccaatctg gtctattttt
     8341 tgctagagcg agagcaatag ctccactacc tgttccaata tccagaactg aaagattcgt
     8401 ctcaagattt tcagttagaa taagctccac taactcctct gtttctggac gaggaatcaa
     8461 aacccgttca tccaccttta aatgcattcc ataaaaatct gcctgtccaa tgatgtactg
     8521 agctggcttg tgagctgcta gttgctggta aatatcttct acaaattgtt tttcttcctc
     8581 tgttgtcacc tcctgctgga gggcaaaaat aaagtctgta aaagatagat ttttcagact
     8641 acgatagaca aaagagaggc tttccgcttc ctctccttgt cttatcaact cttcttcaaa
     8701 atttgaaaat aattgagcta atttcattat ttgtttaatt cttctagttt ttgtgtttgg
     8761 tcataaagca ccaaggcatc cacaacttcg tccaatttac cagacaaaat cgtatctagt
     8821 ttttggaggg tcaagccgat acggtggtct gtgacacggt tttgtgggaa gttataagtt
     8881 cggatccgtt ctgaacggtc accagtaccg attgtcgact tacgctcagc gtcttgttca
     8941 tcctgagcaa tctgagcaaa gtggtcagcg acgcgtgcac ggataatctt catagccttc
     9001 tcgcggttct tctgctgggt acgttcttcc tgcatctcaa ccttgatatt ggttggcaag
     9061 tgaacgatac gaacggcagt cgcaacctta ttgacgttct gtccaccagc accagaggcg
     9121 tgatagatgt cgacacgaag gtcttttgga tcaatgtcgt attcaacctc ttcaacttct
     9181 ggcataacaa gaactgtcgc tgtcgaagta tgaacacggc cttggctttc tgtcacagga
     9241 acacgttgca cacggtgggc acctgattca tacttaagct tagagtatac agactgacct
     9301 gaaaccatag caaccacttc tttaaaacca ccgacaccat tcatagaggc ttccatgact
     9361 tcaaagcgcc aaccttgggc ttccgcatac ttttggtaca tagttagcaa atctccagcg
     9421 aaaagtgccg cttcgtctcc accagctgct ccacggattt caaggatgat attcttgtca
     9481 tcgtttggat cctttggaag gagcaaaatt ttcagttttt cttcatattc ttctttttca
     9541 gccttggcat ctttgagttc ttgcttggcc atttcttcca agtccgcatc tccgcctgat
     9601 tccttaatca tctcttcggc atcgacgata ttttgaagga cttgtttata ctcacggtag
     9661 gctattacgg tgtcacgatt ggaagcttct tcttttgaaa gctccataaa acgcttggtg
     9721 tctgaaacga catcagggtc actcagcaat tctcctagtt cttcataacg gtcttctaca
     9781 gcttgtagtt gatcatagat gttcattttt tctccttatt tctcaattgt taaatcatag
     9841 attgctacta cttcattctc ggatatttcc ccagtttctt taaatccata actgagataa
     9901 caaaatcttg cctgttcatt ttctggttca taagacaacc aaagtttatt gcttaaacct
     9961 gctggcgctg ttcgaacata gtctagtact ttatccataa ttggtttaaa atatccttga
    10021 ttttgaaaat tcttatcaat cataaaacga aatagtaaat aatttccact actaattacg
    10081 atctttttat cataagctat catcacaaaa cctataatta catcattatc ataaactgcc
    10141 aatggagcta caaaatctcc atttttagtg tagacgtatg cttcagctaa actaattgcg
    10201 ttggttgcaa tgaattgttt ttgatattcc ttgacatcca aatttaaaac atcaaaataa
    10261 ttttccattg taacatctct tagttcaatt gtcatagttt tgctccttgt tagaggttat
    10321 cattggcgca aaataatgtt tacggcaaac cgaaatatag gtttcattac caccaatctg
    10381 gatctgttct ccatcgtaaa cgggcagtcc atcctgtgtt cgcaacacca tggtcgcctt
    10441 tttcttgcaa tactgacaga tggtcttgat ttcgtcaatc ttgtctgcta aaagcaagag
    10501 atatttggaa ccttcgaaca attcattgcg aaagtcattt ttcaagccaa aagccatgac
    10561 gggtatgtct aactcgtcca caacacgagc taggtcgtaa acatggtggc gtttgagaaa
    10621 ctgggcttca tcgaccaaaa cacagtaagg tttttctggt aggtctcgga tatagccaaa
    10681 gatatccgtt gtttcctcaa tcgtaagggc agggcgtttc atgccaattc gactcgacac
    10741 atagccaaca ccgtcacgcg tatccagagc cgaagtcata atgacaacac cttttccttg
    10801 ctcctcgtag ttataggcca ctttgagaat ctcaatcgtt ttaccagagt tcatggtccc
    10861 ataacgataa tacaactgtg ccatgtttct tgcttcacgt ccatttctaa atttttgcta
    10921 cattctagta tatcataatt ttcttaagct ttaaacggca aaatgtggta aaatggaaga
    10981 aatcaaaact agtggaggaa gctattatgc catttgtacg catcgattta tttgaaggac
    11041 gcacgctcga gcaaaagaaa gctcttgcta aggaagtaac ggaagcagtt gtccgcaaca
    11101 ctggagcccc tcaatctgct gtccatgtca tcatcaacga catgccagaa ggaacttact
    11161 tcccacaagg ggaaatgcgt actaaataag ctagcttaag cagaattgct taggcttttt
    11221 caatctccaa gtagcattca ttgaagaaat atcctaaatt tgttacaatt tgaaaagaaa
    11281 cttggagaat ttccaagaaa atagctatta attaaaggaa acattatgat tacacgtgaa
    11341 tttgatacca tcgctgctat ctctactcca ctaggtgaag gggctattgg tattgtccgc
    11401 ctgagcggaa cagacagttt tgctattgcg caaaagattt ttaaaggaaa agacttgaac
    11461 aaggttgcca gccacactct caactacggt cacattattg atcctctgac tggtaaagtc
    11521 atggacgagg tcatggtagg agccatgaaa tctccaaaaa ccttcactcg tgaagatatt
    11581 atcgagatta acacccacgg tgggattgcg gtgaccaatg agattctcca gctagctatc
    11641 cgtgaaggag ctcgattggc tgaacctggt gaatttacca aacgtgcctt cctaaacggt
    11701 cgcgtagatt tgacacaggc tgaggcagtg atggacatca tccgtgccaa gactgacaag
    11761 gccatgaaca ttgcagttaa gcaattagac ggctcccttt ctgacctcat taacaatacc
    11821 cgtcaagaaa tcctcaatac acttgcccaa gttgaggtca atatcgacta tcctgaatat
    11881 gatgatgttg aggaagctac tactgctgtt gtccgtgaga agactatgga gtttgagcaa
    11941 ttgctaacca agctccttag gacagcccgt cgcggcaaaa tccttcgtga aggaatttca
    12001 acggctatca ttggacgtcc caacgttggg aaatcaagcc ttctcaacaa cctcttgcgt
    12061 gaggacaagg ctatcgtaac agatatcgct gggacaacac gagatgtcat cgaagagtac
    12121 gtcaacatca atggtgtacc tctcaaattg attgatacag ccggtattcg tgaaacagat
    12181 gacatagtgg aacaaatcgg tgttgagcgt tcgaaaaaag ccctcaagga agccgacttg
    12241 gttctactag tgctaaatgc cagtgaacca ctgactgcgc aagacagaca acttcttgaa
    12301 attagccaag ataccaatcg cattattcta cttaataaaa ccgacctgcc agaaacgatt
    12361 gaaacttcga aactacctga agaggttatc cgtatttcag tccttaaaaa ccaaaacatc
    12421 gacaagattg aagagcgaat caacaacctc ttctttgaaa atgctggctt ggtcgagcaa
    12481 gatgctacct acttgtcaaa cgcccgtcac atttccctga ttgaaaaagc agttgaaagc
    12541 ctacaagccg ttaatcaagg tcttgagctg gggatgccag ttgatttgct tcaagttgac
    12601 ttgactcgta cttgggaaat cctcggagaa atcactgggg atgctgctcc agatgaactt
    12661 attacccaac tctttagcca attctgttta ggaaaataag aaaaatccat gatccttcat
    12721 tcggtcatgg attttattgt ctttattagt aatctggtct taagacccct gttacagttg
    12781 ccttagttgc ttcgtagtcg ccatctacga caaccttgat aatgcgtttg gcatcttctt
    12841 ctggtgctgg aacaagaggt agacgagtgg gtccagcttc aaatcccata tagttaagaa
    12901 ctgccttaac tggagcagga cttggataag agaagagagc attaacctta ggaatgaatt
    12961 tacgctgaat tgctgcggct ttcttcatat cgctttctgc aatggcagta aacatctcgt
    13021 gcatttcatc cccatttgta tgagaggcaa cagaaataac cccatccgcc ccaaggttca
    13081 tggcatggaa agcatctcca tcctcacctg tataaatcaa gaactcttca ggcttgtgct
    13141 caatcaaata agccatatta gccaagctag tacattcttt gacaccgata atatttggat
    13201 agtcagccaa gcgaagcatg gtttctggag tcaattcgac aactacacgc cctggaatgt
    13261 tatagataat aattggtagg tcagaagcat ctgcaatagc cttaaagtgc tgatacatcc
    13321 cttcttgaga aggtttgttg tagtaaggaa caatagcaag cccagctgcg aaaccaccaa
    13381 attccgctac ttctttgaca aactcaatag agtcacgcgt atcattagta cctacacccg
    13441 caatcaaagg aacgcgtcca ttgacaacct tttgtacagc cgcaaacaac tccaactcct
    13501 catcgtgggt caaagttgga ctctcagcag tcgttcctgc gagaagaatt ccatccgtat
    13561 gatgggccaa taaatgctca atcaaggctg gaatagcatc aaagttaatg gaaccatcct
    13621 catggaaggg ggtaataaag gctgtaatga ttttacattc ttttaaatct tgataagaca
    13681 cgaaaacacc tctctatttc aaagaaggag ttcatctgaa ctcctaaacg atatgactat
    13741 tttaattcaa atttcaattc ggctgttgga cgaaccaatc cacgttcatg aagagtttca
    13801 gcaatctgaa ctgagttcca agcagcacct ttgagaaggt tatctgaaac aacccacatg
    13861 tgaattcctt tttctgcatc caagtcttta cggatacgac caacaaaggt atcacgcgaa
    13921 ccaactgcat tgatggcttg aggatagatt tgatgagcta catcatcttc aagaacagca
    13981 cctgggaagg ctgcgatagc tgcttttact tcttcgattg gagccacttc ttttgtttcg
    14041 atataaacag actcagagtg agctgacaag actggaatac gcacacatgt tgcagatact
    14101 gcaatgctat catcttccat aattttctta gtttccttgg tcatcttcat ctcttcgtac
    14161 gtgtaatcat tatcagtgaa aacatcaatt tgtggaagag cgttaaaggc gataggataa
    14221 tgtttcttgt caccacctga aggcaaaatt tccgcatgca aatcacatgg tttcacacca
    14281 tcattcaaga cttcacgaag ttcacgttgt gtctcaagaa ttgctcccat accagcacct
    14341 gaaacggctt gataagttga aacaatgata cggtccaagc cccatttttg gcgaaccggc
    14401 tcaagagcca ccatcatttg gattgttgaa caattagggc aggcaacgat tccgttgtga
    14461 gcatcaagtg catgagcatt gacctctgga acaaccaaag gaacatctgg attttgacgg
    14521 aaataagatg tattatctac tactaccacg ccagctttta ctgcgtatgg tgcatactta
    14581 gctgatgtag aaccacctgc tgaaaagaga gcaatatcaa ctccttcaaa agctgtttca
    14641 gtcgtttctt caatcgtaat atcttgatct ttaaatttca atgacttacc tgctgaacgt
    14701 gcagaagcaa ggtaacggat tttatcgatt ggaagtgttg attcttccaa catttttatc
    14761 atctgagcac cgacagcacc tgtcgcgccg actacagcaa ctgtatatcc cataaataac
    14821 ctctttcgga attttctaaa aatttctata atagaagtat tatactactt tttccatgaa
    14881 ttgcaaagct ttttcatcat tttttggaaa ataaaaatcc ccaatcgcta gactagggat
    14941 taagaggcat cttcatgtga tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt
    15001 tatgacctcc ttatgctcaa tagtagcccg aagactacct atcgactcat cgcatctact
    15061 attctactaa agagaatgac ttttgtcaac agacgaaact ctttatactc ttcgaaaatc
    15121 tcttcaaact tcgtcagcgt cgccttgccg tatgtatggt tactgacttc gtcagtttca
    15181 tctacaacct caaaaacatg ttttgagctg acttcgtcag ttctatctac aacctcaaag
    15241 cagtgctttg agcaacctgc ggctagtttc ctagtttact ctttgatttt cattgagtat
    15301 tagttttatt tacacaggtg cataagaaat atattggaaa aattgggggc agacataaca
    15361 aaaacccttg taaatcaagg gcttttctgt ctatttaatg ctaattgccg ggattgaacc
    15421 ggcgacctca tccttaccat ggatgcgctc tgccaactga gctaaatcag cttacttaag
    15481 aagtatacta taatcagaaa aacttgtcaa gtttccttag aaattttcca taggaaaaag
    15541 ccaggtaaga actacctagc ttatcttctt ctatttactt aaatcaattc gacgaccaat
    15601 tttaccaata ataatcgctc caataatcaa tgaagcaaat tcaccgattc ctgttgtaaa
    15661 ccaagtaagg aagaatggta attctgctac aatatttaac tctgcagcga tagtaaacat
    15721 ggaaattgaa aagaggattg aaaagaagaa atgatctttt cgaatcaatc cgttaaagag
    15781 gtaatccttg ctatattttg caaaaagcca aacacctaaa ctgaggaata ctaaggttga
    15841 accaccacca acaaagacat ctagcagtcc gaagctaaag aaattagcaa tcatacaacc
    15901 gatggtaact ccgatgatgt acttaggatt gtaaaaagcc ataaagttca tcatttctga
    15961 aatacgaaac tgataagcac catagctgat ggcatttagg ggcggtgtga cagtcaaaac
    16021 gacgtagata gcagcgacga ttgcaatatc tgcaacatca cgaatagtta attttttcat
    16081 cttttctcct ttggcggtta tccgcgtgta atatgcttgg tgaaagaagc taagcaccaa
    16141 gggttgattc attcaacctt actagtatag cacaatagcc tgctttatgc tatacttaaa
    16201 gcatgaaaaa acctattcaa aaatttttta acaatgaaat cttagcctat ctcttttttg
    16261 gccttgcgac aactctagtt tcgattctct cacgactagt catttatcaa ctaagtcatc
    16321 aggaactcct tgctacggcc ttggcaaata ttatcggtat cttatttgcc tttatcacaa
    16381 atgatacgat tgtatttaag caaaaaaaga aaaatagact tatccgttta gtgaaatttt
    16441 ctcttgctcg cctttctact tttctgttag acttgttttt aacttttctc tttgtaaccc
    16501 aatttcctca catcataggg caattcgtaa ctgaaaacat tgataagata aatgctattg
    16561 aaacaataat tgcacaaata ttcattatta tcatcaatta tatcttgagc aaggtctata
    16621 tttttagaaa ataatgctcc atttatgagc cttttaattg ccttctataa tgatttagga
    16681 tacaatgaaa cacgaaacat tgaaaggaaa acagtatgtt aaaaaatcta aaatcgttct
    16741 tgcttcgagg aaatgttatt gaccttgctg tcggtgttgt cattgcctct gcttttggtg
    16801 ctatcgttac ttcacttgta aacgacatta tcactcctct tattttaaat cccgctttga
    16861 aagctgctaa agtcgaacgt atcgctcaac tttcttggca tggagtcggc tatggtaact
    16921 ttttaagtgc tattatcaat tttatctttg tgggtaccgc cctcttcttt attatcaagg
    16981 gcattgaaaa agcacagaaa ctgactggca taaagaaaga aaaaactgcc gaaaaaaaac
    17041 caaccgaatt ggaagtcctt caagaaataa aagctctcct tgagaaaaaa taatcgatta
    17101 aaaggatcta gcgcaaagct aaatcctttt ttctttactc tttgggtaac ttgcctgctt
    17161 tttcaagcat ttttttgata agataaggca tcttaacatt ctcccgccct tttttctcaa
    17221 tcagtttttt cacaaattct ggcatttgta aatcttcaga ttcagctaaa atgtttttcg
    17281 tctcgtctga aggaactaac tcatcaaagg tctcttcttc tgggagaaat tccttaaact
    17341 cttgattttc attgactcta actgtattga ccaaagcatc aatcaaacga gaatctgtat
    17401 ttggcattgg tggacgatgg tagtttaccc caaattcctg gcataagtca taacattcta
    17461 catcattgtc aaacaagacc tcaatatgct cactgatgaa actaatagat acaaaaatat
    17521 aatggtctgg atgttctgtc tgttctctga gatactccaa aacatctggt ttaatccatg
    17581 gaataccaat atcactctca ctctgccaag tgttggtata ttgttctgaa ctcaagccca
    17641 gtttttcagc gactagcttg ctattttcga aaatttggtc tatataagga tcaccaaagt
    17701 ccaaggcaaa aatgggcaca ctatgggctg aaaagatgac tttaaagctg tcttgcttta
    17761 cttcttcttt taaaatctta gcaatttcat ctgcccaata gtttaagagc gcttcttcct
    17821 gataccagtc cttaatgacc aaaaattgaa tttgtttgct ttctaaaaat ttttcatagc
    17881 ccatgacaga gtagaaagaa taatggggct ccaaaatcaa gcaaatacac tgttcaattc
    17941 cgtctgcttc catttgaccg atcacatctg gaataaaggg actggaaaac ttattagcaa
    18001 agtagacact gtattcattc cccagcctag cttctaccaa ggcaacctct tgacgggtaa
    18061 ttttttgcag aggcgtgcct ccaattcgta cataattatc atagagagtc tgaatctcgt
    18121 ggtcttgggg tctcacccca cgacgaatat ttgtgaaaaa atcagctaca ccttcaaagg
    18181 taatctcttc tggtgaaccg aaggtcatca ttaaaattgc ttttttcatg actgcttcct
    18241 tgtgatgttt ttatcaagtt tattttatca ttaattcatc gataagtaaa cgctaacata
    18301 gggacattct caatcttctg tcttttgttt ttctcttctt tctatgatac aatggaaaaa
    18361 ataaattcaa aaggagtttt tttatgactt atccaaatct cttggaccgc ttcttaacct
    18421 acgttaaggt caacacgcgc tctgatgaac actctactac tactccaagt acacagagtc
    18481 aggttgactt cgcaacaaat gtcctaattc ctgaaatgaa acgtgttgga ctgcaaaatg
    18541 tttactatct accgaatggt tttgctattg gaaccttgcc agccaacgat ccgtctttaa
    18601 cacgtaagat tggttttata tcgcacatgg atactgctga ttttaatgct gaaggagtca
    18661 atccacaggt aattgaaaac tacgatggtg gtgtgattga actagggaat tctggtttca
    18721 aactcgatcc agctgacttc aagagtcttg aaaaatatcc aggacaaacg ctcatcacaa
    18781 cagatggaac aagcttgcta ggtgctgatg acaagtcagg aattgctgaa attatgacaa
    18841 ccattgaata tctaactgct catcctgaaa ttaagcactg tgagattcgt gttggttttg
    18901 gtccagatga agaaatcggt gttggtgcca ataaatttga tgcagaagat tttgatgtgg
    18961 attttgccta cactgttgat ggtggtccac taggtgaact tcagtacgag actttctcag
    19021 ccgctggtgc tgaattgcat ttccaaggcc gtaatgtcca ccctggtact gccaaagggc
    19081 agatggtcaa tgcccttcag ctagcaattg attttcataa tcaacttcca gaaaatgacc
    19141 gacctgagtt aactgaaggt taccaaggtt tttaccatct aatggatgtg acaggtagtg
    19201 ttgaggaggt gcgtgcaagc tacatcattc gtgattttga aaaagatgcc tttgaagcgc
    19261 gtaaagcatc catgcaatct atcgctgata agatgaatga agaacttggg agcgaccgtg
    19321 tcactctcaa cttgacagac cagtactaca atatgaaaga agtcattgaa aaagatatga
    19381 ctccaattac cattgctaaa gccgttatgg aagatctagg tatcacgcct attatcgaac
    19441 caatccgggg tggaacagac ggctctaaga tttcctttat gggaatccca actccgaata
    19501 tctttgcagg tggcgaaaat atgcacggac gttttgaata cgttagcctt cagactatgg
    19561 aacgtgcagt tgataccatc attggcatcg tagcttataa aggctaaaaa gacgaggtag
    19621 ctcagctact tcgcctttct ttttattcta ctggtttttc ttgatttcca gtagttgtag
    19681 aagattctgt tgtttcattt tctgaagttg attcagcagg tttagaatct cttgtattgc
    19741 ttggtttgtt ttcgtcgcta gcagtttcaa tgttagattc tgcagttgcg tttggttggt
    19801 tctcagcact ggtgttatca ctatttgctt cagcatttct tgctggactt gtttcttcac
    19861 ttgcgctagc ttttgactgg atttgatgat tcaaaactag aatagctttt gtcgattcaa
    19921 gtaaagctgt tttgtcttta ctcttagcag aaagttgatc taataatgca tccaccttat
    19981 caaagtccgc atcagatcca ttattacttt ctaaataaga gtgaagcgac atgagaatat
    20041 cgtagagttt ttgatagagt acaagtgtct gagaatcttg ctcagcattt tccttttctt
    20101 gttgaagggc gctagcgata cgagtcaaaa catcttttac ctgactgttt acttcatcca
    20161 agtctgcatc agccttgttt gtggcagctt ttagattttc tacttcttct gccaaggatt
    20221 gtctgattcc ttcttcatgg atttgttcca agagttgatt tgcattgttc aaaagacttt
    20281 ctacttcttc ctttctatct gtcgcagatt attggttgct atctaccatg tactcctaaa
    20341 acaggagagt tataatccaa gattacaagg ccttacagaa ataagaaatc cagataagac
    20401 aatgttcgtc caagacgcta ttcgcttcgc acagcagcac agattcaata tactttaatt
    20461 ttaaagttta ggtgtcaaga cctcttttta gtgtgcccaa aatttagaga agtaatcaat
    20521 caactaactt ttattttttt caaactttca gtaaactgac ctaaagctaa ctcaatctgt
    20581 ctttgtagat gcttctgcta tcagctagaa gttgatctac ttttgccaag actgccttct
    20641 catcaaaagt tccaggttga tagttggatt gcagggatgg aatcttgttt ttcaaagccg
    20701 cttcatatcc cttagtttga accttgatgt agtgattgtg gtcgccatga ggaatcacaa
    20761 aaccttctga atcttcactt ataattcgat tggcatcaaa aaccatgacc atcttcttcc
    20821 tcatggtgga catgtagtga cggattactt aatacagaac tagaagaact tcctacctct
    20881 tccgtgttag agtgtgatgg gggattgtta agagatgact taggaatata gtgatagtgt
    20941 tccccatgtc ttactatata agcatcacct atatctctga caatatcatt agggttaaag
    21001 acatatgtgg ctgctaattc acctgccgac aagtcactct caggaatgaa atgatagtga
    21061 ccaccatgtg gtactatagt aggttgaaat agaatatgag caaattgata aggggatttt
    21121 aaagtaattt ctaacaatga tttagaaact atgatgtgct attctaaatt caactcacta
    21181 tatataacca tcatcggtag tataacgtcc ctgtaatttt gctacagata cttctgcact
    21241 agctccttta tcgtctttac catgttcttg tttttggcga ttgatttcat cttttgttcg
    21301 tacattttct gcatgagctt gatctttaag gtaaacataa tactttccat ctaccttaat
    21361 aatatatcct cccttaacct aactgacgat atcttgatct ttcggctgat agttgggggc
    21421 tttcattagt agctcttcac taaagagcgc atcaaaagga actttaccat tatagtagtg
    21481 ataatgatcg ccatgagaag ttacataacc ttgatctgta atcttaataa caatttgttt
    21541 tgcttgaatt ccttcttttt gactaaccta gtctggagtc aaattttcag tcttcttagt
    21601 gtctttatta ctgtttacat atgaaacacg atttttatct gtattggcct gttagctatg
    21661 ttggttcaga gcataaacac acagacttaa ggaaaggata acaacagatc cagctgctat
    21721 atatttcttt ttaaatttca taattac
//
LOCUS       DBERDS010000031        20693 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.031, whole genome shotgun sequence.
ACCESSION   DBERDS010000031 DBERDS010000000
VERSION     DBERDS010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.031"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(509..2236)
                     /gene="ezrA"
                     /locus_tag="ACL73E_001355"
     CDS             complement(509..2236)
                     /gene="ezrA"
                     /locus_tag="ACL73E_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGS0801315.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2318..4264)
                     /gene="gyrB"
                     /locus_tag="ACL73E_001356"
     CDS             complement(2318..4264)
                     /gene="gyrB"
                     /locus_tag="ACL73E_001356"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGS0801316.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4279..4842)
                     /locus_tag="ACL73E_001357"
     CDS             complement(4279..4842)
                     /locus_tag="ACL73E_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0801317.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4927..5481)
                     /locus_tag="ACL73E_001358"
     CDS             complement(4927..5481)
                     /locus_tag="ACL73E_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGS0801318.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5492..6715)
                     /locus_tag="ACL73E_001359"
     CDS             complement(5492..6715)
                     /locus_tag="ACL73E_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGS0801319.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6752..9202)
                     /locus_tag="ACL73E_001360"
     CDS             complement(6752..9202)
                     /locus_tag="ACL73E_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGS0801320.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9402..10331)
                     /locus_tag="ACL73E_001361"
     CDS             complement(9402..10331)
                     /locus_tag="ACL73E_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGS0801321.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10471..10758
                     /locus_tag="ACL73E_001362"
     CDS             10471..10758
                     /locus_tag="ACL73E_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGS0801322.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10792..12126)
                     /gene="ciaH"
                     /locus_tag="ACL73E_001363"
     CDS             complement(10792..12126)
                     /gene="ciaH"
                     /locus_tag="ACL73E_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGS0801323.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12116..12790)
                     /gene="ciaR"
                     /locus_tag="ACL73E_001364"
     CDS             complement(12116..12790)
                     /gene="ciaR"
                     /locus_tag="ACL73E_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGS0801324.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12899..15445)
                     /locus_tag="ACL73E_001365"
     CDS             complement(12899..15445)
                     /locus_tag="ACL73E_001365"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGS0801325.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQHLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15568..16008)
                     /locus_tag="ACL73E_001366"
     CDS             complement(15568..16008)
                     /locus_tag="ACL73E_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGS0801326.1"
                     /translation="MIPQEMWNKYKQINPSIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15983..16852)
                     /locus_tag="ACL73E_001367"
     CDS             complement(15983..16852)
                     /locus_tag="ACL73E_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGS0801327.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16830..17330)
                     /locus_tag="ACL73E_001368"
     CDS             complement(16830..17330)
                     /locus_tag="ACL73E_001368"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGS0801328.1"
                     /translation="MEIKKHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17341..18039)
                     /locus_tag="ACL73E_001369"
     CDS             complement(17341..18039)
                     /locus_tag="ACL73E_001369"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGS0801329.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18032..18268)
                     /locus_tag="ACL73E_001370"
     CDS             complement(18032..18268)
                     /locus_tag="ACL73E_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGS0801330.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18368..19294)
                     /locus_tag="ACL73E_001371"
     CDS             complement(18368..19294)
                     /locus_tag="ACL73E_001371"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGS0801331.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19369..20184)
                     /locus_tag="ACL73E_001372"
     CDS             complement(19369..20184)
                     /locus_tag="ACL73E_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801332.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20188..20508)
                     /locus_tag="ACL73E_001373"
     CDS             complement(20188..20508)
                     /locus_tag="ACL73E_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGS0801333.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6223 a         4540 c         3674 g         6256 t
ORIGIN      
        1 tagtctagta taaatagcga gaaatatcta tcctatcttc tagaatgtct tccaaacgag
       61 aaaactctcg taaacaaaga ggttttagag gcctatttac cgtgggacta aagttgtaca
      121 agaaaagtgc aaataagaaa tctccagatt aggaactatc cgtgagttct ctagtctgga
      181 gatttttcaa tagacttcgt tattggacgg ttaccaagtt actcaaagta cagatttgaa
      241 gctgcagata agactgacga aatcacttta atactaaatg aaaatcaaaa agcaaactaa
      301 gaagctagcc tcaggctgta cttgagtacg gtaaggcgac gctgacgtga tttgaagaga
      361 ttttcgaaga gtataaaaca ctgttttgag gtggtggata aatcggctgg gtaaaaactc
      421 aatctcagga gaaaatgaag taaatctccc cacaactata gaaaaagatt tgattctgct
      481 cctcacacaa taaaatcttt ttcttttatt aaaaacgaat cgtttcacgt gttttctcat
      541 atgaggtaac aaagcgattg gttacaccag gctctgccac ttccaatgct tgagaaatct
      601 tgtcaaatga agcgtgataa tcaaattctt tttcaaaaat atctaaagct tcgttaaatg
      661 cttcttgaat gcgttcatca aatgagcgat agcggttaga atattgcaag agttgctctg
      721 tcaaagttgc atattgtaca atattataag tttccgtttc taaagcttcc atatcattcg
      781 ttgcaatttc aagaactcgg gtaacagatt caatgttaat cattttttgt tctaactcaa
      841 ccattaaatc ctcggtatta ttgcttgccg taaagaataa cttcaagaaa gtttgtggaa
      901 tacctggcag attgcgtttt tccatgtatc gcttgatagt atggagacga ttgacataaa
      961 cattggcctt ttgacgtgca ttaatatcat ctttctcaat ttgtgtcagg cgctcactaa
     1021 ctgaaatttg ctcatcttca atatctttta gttgagtttg taaatcctca agattttctt
     1081 caagaactga ataagcttgg gttggttctt cttgattcga agttacctca acaatagctg
     1141 cctcaaaact ctctaattct gtctgaatac gacgaacatg gcttgcagct gtctcaggaa
     1201 gtaaataggt cttgttcaaa cgtgcaatat cttctcccaa taaagtatta ttctctttca
     1261 tatgttgaag gtaagttgga agagttgcaa gtagattttc cactactttc tgagcagcaa
     1321 tttctcgagt aaaaatatca tacaaggcat tgatttcctc ttgtgcctgt ccattctcat
     1381 attcggcatt atccaattcc aactgacgaa tattctcttg gtttttcttg aatgcttcat
     1441 aaagcaagtg gaaacgcgct tcaatatccg tttcaacaaa atgataatta gcatcaatta
     1501 gtttacgata accggcttcc aaatcctgta attgatctgg caattctgta gaaagcgtcg
     1561 taaccaaggc tggaacacga tccacaatat gacttaaggc caaaatgtga ttttctgtat
     1621 tatccaaaat cactgcggct tccacagggt cacccgatga attcaaggtt acaaattgtg
     1681 aaaattcaga ttggatattt tctaattgtt tttcaatttc atccaaggct tgaccatact
     1741 gttctgaatt ttcagcaact ctatgctgaa gttcctcaaa taaatccaaa gcatgaagaa
     1801 cacgaccact atttttagat tcttgcttct ctaagtctgc caaagcattg cgaattgccg
     1861 caatatcttc ttcaatcaaa gtaatttgac tctcaatttg gtcaatttga tgactggcct
     1921 tgagaaaacg aaatgaatgg ttatagcctt ctgcttcaaa gagattattt tcaatatcgg
     1981 caaaagagtt gagagataaa tcgacccatt tttgattcca ttcacggaaa gccacttgac
     2041 tttgtccaat caagtgcata ttttttacag cttctacttc atcatttact ggaagattgt
     2101 atagttcttc ttttctttct tctagcgcct ctaatctccc ctcgtttcgc ttacgtagaa
     2161 agattgccac tacataagcc agaactaaaa tgactgcaat tgcaaccatt aaataaatta
     2221 gttgtccatt agacatatca aactcctttt ttacttgaaa caatcgtaac gattatatca
     2281 tattttttag accaagggaa ctacttctcc ctatttttta gacatcaagt gtactataga
     2341 cagcattttc ttcgataaac tcacgacgag gctctactcg atcccccatc aacatatcaa
     2401 agattttatc tgcttctgca gcatcatcta cagaaactct agccatcaag cgatgttcgg
     2461 gatccatggt tgtttcccac agctgatgat cgtccatttc acctagcccc ttataacgct
     2521 gaatagtcgg tttggtacga ccttcactat aacgggctaa agcttcttgg agtttgattt
     2581 cttgatctgc acccggctgg atatattctt taatctcgct tccaaccttg acaccataga
     2641 ttggtggttg ggcaatataa acataaccag cttctaggat tggtttcata taacgataaa
     2701 tcaaggttaa aagaagggta cgaatgtggg ctccatcgac atcggcatcg gtcatcaaaa
     2761 cgagtttttg gtaacgggct ttcgaaacat caaattctgc gccaaatcct gttcccatgg
     2821 ctgtgaaaag actacgaatt tcttcgttag ctagaatctt atccatactt gctttttcaa
     2881 cgttcaaaat cttaccgcga attggaagga tagcctgaaa ctcacggtta cgaccagatt
     2941 tggctgatcc accagctgag tctccttcga cgatgaagag ttctgtttca gcagggttat
     3001 tagaagaaca gtctgctagt ttccctggaa ggttggaaat ttccaaacca gattttttac
     3061 gtgtgacttc acgcgcacgc ttggcagcca cacgagcctt ggcagctaaa atcccttttt
     3121 ccacgatacg tttggcaatc tgtggatttt ccatgaggaa atcggagaag gcttcactga
     3181 agaggcgatt ggtaatcttg accacttcgc tatttcccaa tttggtcttg gtttgtcctt
     3241 caaactgtgg atttgggtgt ttaactgaga taactgcagt taagccttcg cgaacatctt
     3301 cccctgttag gttgtcttca ttgtctttca gtaacttatt tttacgagca taatcattga
     3361 taacacgtgt caaggctgta cggaaacctt gttcatgcgt tccaccttca tgtgtatgaa
     3421 tattattggc gaaactcatg acattttcat ggtaaccagt tgtgtactgc atggctacct
     3481 caactgtgat atcatccatc tcaccgtctg tatagattgg tgtatcaaag attacatcct
     3541 tgttctcgtt gatatattca acgtaactag caatcccacc ttcataatga taatgcttgg
     3601 tttgttccaa accttcacgc ttatctgtaa ttgaaatttg aagaccgcga tttagaaagg
     3661 ccaactcttg aatccgttta tttaatttat caaaatcaaa gattgttgtt tcagtgaaga
     3721 tttttgggtc cggtgtgaag tgaacagttg ttcctgtttt atccgtatct ccaactattt
     3781 caagatctgc gacaacatga ccacgacggt attcttggta atgaatctta ccatttttgt
     3841 gaacatgaac gtctaattga gtggaaaggg cattaactac tgacgacccc accccgtgaa
     3901 gaccacctga aaccttgtat ccaccaccgc cgaactttcc tccagcgtga aggactgtaa
     3961 agacggtctc aacagcagga cggcctgttt tttcctgaat atcgactggg ataccacgcc
     4021 catcatccac aacagtaatc gaatcatctg gctcaataaa aacttgaata tggctggcaa
     4081 atcctgccaa ggcctcgtca attgagttat caacaatttc ccagactaga tggtgaagac
     4141 cttcttttga ggttgatcca atgtacatcc ctggacgcat acgaacagcc tctaagccct
     4201 ctaaaacttg aatttgactg gcatcataat cctgtgcctg cagatttttg atttcttctg
     4261 tcatcttatt cctttttctt atatgtctaa tacttgtctt aaattcacga tactggtaaa
     4321 caagtgggta tcaagtcctg cagcttgacc tgcttcgata tcaatcggcc gatcaccaat
     4381 gacaagacca gagctaatct gatacttttc tcttaaataa agcatggatt cgggatttgg
     4441 ctttctctta aagcctgagc tagaagtcac cacttctgta aaataagctg ctatagaggt
     4501 tttttctaaa atttccaaaa cctgatcatt tcgatgagag accaaaaaat gacggccacc
     4561 ttgatttgaa atgacttcca ataggtcaga aactccttca aataaaatcg ggtgttcaag
     4621 ctctctggct tcattttcct tgtacttttc taaaaaattc tctaaattgg gagcgaatgt
     4681 ctcaatcgca aaaggagtag aaacctttaa agcttgatag acactgtcat ggtcttgtgt
     4741 gataccatac agtgccaatg tttcaacaaa tgcagctgtt gaagtttcat aattatccag
     4801 taaagttcca cctaaatccc agatgtaatc gtgatatttc atacccttca ttatagcatt
     4861 tttttatgaa aaaagcgatg atttccctga gttttccaca taaaaaacga gagaataact
     4921 cccgttttac tgatttttac caaagacatc ttgatagagc attcctgttc gtaaactctc
     4981 tgcgtcccct cctagttgct ccaccaactc gtaggcaaag gcaagggctg ttgaaggacc
     5041 ccgactggtt gtcaactgac catctaccac tactgtttcc ttgacatagt gaccatcaag
     5101 gatttgctct tgaacgccgt cataacaagt gtatcgctta tttttcaata tctctgcttg
     5161 attgagggca attggtgccg cacaaatggc tgctagtttc ttcccttctt gctcgaagct
     5221 ttgcaattct tgaatcaagg tctgattatc acgtaaatgt gcagaaccag gcatacctcc
     5281 aggaagaaca atcatatcat agtctgataa atctccatca aagacatgat ctgctcttac
     5341 ttggattgca tgcgaacccg ttacttgctc ttcaaaacca accatatcac atgtgatatt
     5401 ggctcgacgc aagacatcta caactgtcaa ggcttcaatt tcttcaaagc cctgagctaa
     5461 cataactgct acttttacca tgattttctc cttatttaat ttgttttaat acaacctttt
     5521 tccgtttgaa tgggactttt ccgctctttt cttcagctag attagtctgg taactcatcg
     5581 ataaaagcaa accaacacca atcagattac tgataatagc tgatccccct tgcgaaatga
     5641 aaggcaaggg aatccccgtc aaaggaagta gtccagtcac agcaccgata ttctcaaaga
     5701 tgtggaagag caacatcata atcaaacctg tggaaatata agtgtagaac tggttatttg
     5761 atttaagagt aatcttcaac atacggtaaa tcaacatgag atagagggca ataaccagga
     5821 cagagccaat aaagccaaaa tcttctgcaa taaccgtaaa aatcatatct gactctcgaa
     5881 ctgggataag cagattcgaa gcattaaatc cctgaccaaa taagccacca ctcccaatgg
     5941 caatctgccc ttgagcctgc tggtaagtcg ttgtttgggc aaactcaaag ggattgagcc
     6001 aagccaaaat ccgattaatt tggtaggtcg gcattccaat ctggtgaaga aaagctcgtc
     6061 cgtccttgct aataaagata gctaagaaac cagcaactcc tgttacagca gtcacaaata
     6121 ctgggataat aattttccaa gaaacccctg ataataaaac gattcctgag aaaatggcta
     6181 caaaaaccaa agccgtcccc aagtcacttt gaagtgctaa aagaactagg actggaatgg
     6241 taaagagaat catccagaaa attaacaaaa agtccagcgg aaccgtgcgt ctccattcct
     6301 tatgtttctt tgtaaattgg acaatgacac gagccaacat gaggatatag gatatcttca
     6361 taaattctga cggttggaat agggtaattc catttattga tacccagttt ttggcacccg
     6421 ttgatgcaac taagcttgga ttataaaata caatcggcaa gatcataagt cccaagccta
     6481 aaatatatag aaagggggtc accttccaaa gaaattctgt attaaagagc atgaccacaa
     6541 aaccaatcac aagccccaaa gcaatccagg cgacctgctg ccctaaaatg ggcagaatat
     6601 tattgggata atcatgacta acggctatat agatagccac cacaccgatg accagtagaa
     6661 aaaatactgg caagagcaaa ctgtaatcga ctcttgagtc gagagaacgt ttcatatata
     6721 ctaaccttat actttcatac aatactattt atcaaagttc attaaaaaat ctatcaatag
     6781 cctcgtcaac ttcggatcga gagatggttt taacagtcgc ttcttctgct agagatgcta
     6841 ctatttgttt gccgtatcgt tttccgacga ttctcctatc caaaataaga gttaaggaac
     6901 gttggtattc acgtctcata cttcttccca aagcctgttt taaacgaata atggccattg
     6961 gcaattgata atcataaaag gcatttttcc cttcttgatt cagttcttga ttaatctttt
     7021 tcgtcaaggg ttcttgagga ttttggaaag gaagcctcgg tacaacttga atcacaaaag
     7081 gatggcttga aaaatcaact ccctcccaga aacttgctgc accaagcaag atttgttgtt
     7141 cacctttttc aaagcgtttc tttagctgat gaacatcccc atttttatac tgggccaagt
     7201 ggctaactgt aagtaaatcc gatactgcta gaagcatgtc tttagcggta aagagaacca
     7261 aaatcggttg ctggaaagct tgaatttcca ctagtaaagc agctacctct ctggcataga
     7321 cttctaagga ggtttctgtt accagaggga aatctttgac catgaccact tcttgttcct
     7381 gttttccccg agattcaatc ttgacaaatt tggcttcagg atagcctaaa aggtctgcca
     7441 aagaaaccct ctgactaatc tcaagagtag ctgatactcc caagacttgg caactctcag
     7501 gaagtaaaga ggacagaaga gtacggcctg attttgtaga agaaatctga attttctttt
     7561 gactcgtttc agttacttca agccagtaat caccttcagc tgtaaaatag cgaaccagct
     7621 catcaaagcc ttccacttct aattctgaaa aatactgatg gagattgtcc agagaatcta
     7681 agatattttt cctagatttg ccagactgaa attgttctat caagtagaga cactcaaagc
     7741 gaatactttc tagtatccgt tgttgaaccc tgttttcttc tcctactaaa gccttatcaa
     7801 ttaaatcgat aatagattgt atatcgtagg tctcttgaag cagattttct agagctaaca
     7861 aaatcttttg gacttcatca ataatcagta aacggtcact gacaaattca ggattatctt
     7921 caagtctggt cacgagatag gcatgattag tcactaaaag cttgcaagtc tctgcccttt
     7981 cttgactacg tttccaaaaa tcttccgtca caaataagct ctgggatgat aaattcccat
     8041 catgacgaag gtctgctaga aaatgttggt aacggtagag ttgcccgatt tcatccaaat
     8101 ctcctgtctc tgtctcagta agccagacca agacttgcat tttaaagcgt ctaaataagc
     8161 gattttcatc attttcctgc aaggaatgat aaaaggcatc caacttcaga taattttgtg
     8221 gtccctttaa gctatgaata tctgtatgga acacttcctt gagacgttta ccttcttctt
     8281 ccatgatttg attttgaaga atctttgtcg gaacactaag aacaatttgt cgctctttgg
     8341 attgagataa agcgggtaag agatagccat aggttttccc aatccctgtc ggcgcttgaa
     8401 tcagagagac aggttcatct ttcaatagca agccaacctc tttagcaaaa ctttcttgtt
     8461 cctccctcac ttcaaggttc aacagagaaa tatttttaga aaagtcttga gatagttttc
     8521 gtagctccag agaagctgcc gttttcttaa aatacagacc ttgaacttgg accaagtctg
     8581 gagaactcag gatagattgg ttgcgataag tttcctcaat aaccaggtag gactcatata
     8641 ggagagcgtc agccatttcc agcaagcgtt ccaagagacc tttaggaagc tgggtcatct
     8701 tttcccgtaa aaaaagaagt aattctgctg tagcttgggc atctgaaagg gctgtgtgtg
     8761 cgtgtttaag aggaattcct aattctcgac acaaaatcgg caagctatat ttttccagtt
     8821 cagggaaaaa gacctgggcc aattcgaccg tatcaacacg agggtttctt agctcatagc
     8881 cttcaaaaaa taaattttcc gccaagagat tagcatcaaa ctgaacatta tgggctacaa
     8941 aaatcccatc ctccaccaag tcaaatattt ttctggcaac ttgcgaaaaa tcaggtgctt
     9001 gcgccagacg ttggtctgtc aatcctgtca gttctttgat atgagcatcc aagggttcat
     9061 gtggattgac atccgtcgta tagtgatcga cgatttctcc gtcctcaatc acgacaattc
     9121 ccacttggat aattttagcc ttactacctg tgctagttgc ctctaaatcc accacaacat
     9181 agcgattacc aatcgttttc attataaaaa attataccaa aaaaagggcc atttggcacc
     9241 tgcaaacata ggataatttt caaactcaag aacactactt ttcttaaaaa tcccatcgaa
     9301 tagagcattc tagcctgctg atttttgtaa aatagtgaag aaatacgaaa aattgagaga
     9361 agaaatgttt gcatcttcct tctctcaacg aatcatgtat tttatctaac catgtcagga
     9421 tcgtagtcat aaaatcctgt atcaaggaaa cggtttttag ggtgaagttt acgaacttct
     9481 tcatccagca agaaggcttg atcatggcta aagttgccct cttgaatcaa attacgcgct
     9541 tggataaaga gttttgcaat ctcaacaaag ttctgaccag gagtgtagag cccttctagt
     9601 ttccagcgag taaagccatg ctccaccaat tctgttaatt tgatcatcaa atcaaggtca
     9661 ttgttggcaa agatatgggt cccatgatta tcttcaaaaa tggaatagtg gctctctgga
     9721 tcacttggct cagccaagaa gaggtcacgt ttatgcgtct tttcatcatc gatatgtgta
     9781 aagttatagt agttttgcaa gagtggacgt ttagaatgat ggatgacgct agcaccgtaa
     9841 accaaaactt cagcaggaat ttccaaaatc tctggcattt tgaaaagttc agctgatgga
     9901 atttcacgcg ccaaaacagc ctcagatgcg ccagcctttt gcccccagaa gttaatctga
     9961 cgactgctag ttaccatggt tgaagcatcg tagatggtct taaatgaata accatcgcgg
    10021 ttaactacgt aaaagacgcc tgcatcccca atcgtaatat agtctgtctt gatttcttcc
    10081 aagaagtcta agaaaggctt gatacggtcc atcatatctt ggtgcatgag agcattgacc
    10141 gcaacgagca attccttacc agcatcatga accaacttag cgatttcacg taattggtca
    10201 taactaaagg tcgttggcag acgaaggcca aaatctttct caccgacata gatacggtct
    10261 acgccagctt cgagtagttg ttcaacttgt tcaatacttt cagcagttgc tgtaatgaca
    10321 atcttttcca taagaaaaat tataccacat ttctccaaaa tcagccatgc tttgaaaatg
    10381 aaaagggact ttattctttt tgtaaccttt ctgtaataat tctctgccga aaaaatgata
    10441 aaataggtat gtactgttaa ggagagaatc atgcccgtaa gaaaattaca atcctatgag
    10501 gtagactatc aagaagaatt aaaccagcag cttcctcatt accaagctta tacacctgaa
    10561 gcgcaatctg atgccaatct caaggaaatc ctatttttta ttaatatcgc tgttttttgt
    10621 atctgtattg ctatctttag ttttatcttt ttagcattaa aattatcaac tgctcttgcc
    10681 tttgccgcag caatcggatt cagcttactt gttttaaaag ttcaacggtc tattatcaaa
    10741 cgaaaacgta gaagataaat ccaaaatatc gccccaattg gagcgatatt tttatttttt
    10801 ctttttagat ggtgtctgaa tggcaatctt cacttcaaag attgttccct tgggtttatt
    10861 atctttgaca gtaacagttc cttttagagc atctacaatt tgcttggcta gggataatcc
    10921 taaaccaaaa ccaccttttt gccgggttct agctttgtct actcgataaa aacggtcaaa
    10981 aattttcttt ttatcttctg tcgaaatacc gattccatta tcagaaacaa gtaaataaag
    11041 attgcgatcg gtcgccgaga taagaaaatc aatttcacca tcctcctcag tatacttgac
    11101 ggcattatcg aaaagaatgg tcatcagttg tttcagaaga agctgatctg tgacaattgt
    11161 tcgatggata cgattttcaa aacggaagac acgattattt tccgaagcaa tcatctcgta
    11221 gtttgtgaaa gttgtattaa aaaagctagt tggaacttct gcaagctccg gcttaatccc
    11281 atcatctctc cgagctaagt tcagcaagct tgtcgttaaa aaacgcatat ttcggacttc
    11341 ttccaaactc gatgcaatgc tttcgctcac atccataatg gtagcttctg gcttacgaaa
    11401 aagggtctct aagcgatttt gcaaaactgc gagtggagtt cgtaactcat gactggcatt
    11461 ttccacaaaa gactgttgct tctgcatact ctcaagcagg ggcctaacac tgaccctagc
    11521 tagatagaga ctggcaagta aagacaaaat ccagaaacta gccatcacga ccacaatcaa
    11581 ttgctcatgc ttttgactag cctgctccaa ctgactggta ttaatcaaga cagcagcata
    11641 ctttatattg gttgaaaccg aactaatatt ggtctccatc aaaatcacac gatagatttc
    11701 ttcctgccca tagctattaa aaacctgaat ctggtagata tgtcctagtt ctttcttttc
    11761 taacttaatc ttatccaagc ccaaaaatcg atttccagaa agaagttgag taaagtcttt
    11821 atcaaagaga atgacttccg tattggaact gacattaggt tttatttcta ctttactagc
    11881 gtccgcccta gcattttcta aatctttaat ctcttctgtt gccctattta tagccagctg
    11941 aataactgct tgaggatttt cactcagtcc atgaagctta tcgtccaccg aagtataaag
    12001 actcgaatgc atgacttgta aaataatcag agtcattgta gaaaaaatca gggtgaagac
    12061 accgaagttg cggataaaat aactaaagtc atccgcatac catgtttttt taagtttact
    12121 gaacatcttt taaaagatac ccaacactac gcaaggtttg caaattctct gcaaaagtgg
    12181 ttccctttaa tttcttacgg acttttgaaa catagacttc gacaaccgaa atcgttgtat
    12241 cactatcaaa tccccataga cggtcaaaaa tctgcgtctt aggcaaaatc acattttgat
    12301 tttgaaggaa ataaactagt aaatcgaact ctttccccag caattcgaca ggagtatctt
    12361 caactttaac ggtattggtt gataaattaa ccacgatatt cccataagtc aaggtgtttt
    12421 cattaaactt ccctgaacgt ttgagaaggg cctgaatccg cattttaagt tcttctaggt
    12481 agaaaggttt ggtcagataa tcatccgctc ccagttcaaa tccatgtccc ttgtcatcca
    12541 aactttcctt ggcagtcata atcagaactg gtgtcgtaat tcccttttca cgcaattctt
    12601 ttaagacttg gaaaccattt ttttctggca acatcaaatc cagcaaaatc aagtcataga
    12661 caccactctc agcttcgtag agaccttctt ctccatcaaa tacctgcata acatccgcaa
    12721 aatcgtctaa aaagtcaaat actgaatttg acagacctag gtcatcctca accaataaga
    12781 tttttatcat gagaaactcc tccttattaa aactattata ccaaatttgc cttaaaaaaa
    12841 actcaactct ctgcatttta catgagatag ctgagttttc tttttatttt aggcttattt
    12901 atgcatttcc gtattgaaga acaactgctt cgactgcagc tttttcacgg ctaatcaagt
    12961 caacacgcgc tgcaatttcc ttgattccca taccgatgtt acggctaaga gcaaggtcag
    13021 aaagttgcgg ctcaaagaac tccttgtatt ccgccaagtg ttgctgagtc ttaaatacat
    13081 gagcaggaag gataacaaag ctatcaaagc tcatatctcc tccaagggct gccttaatcc
    13141 aagcccagtt ttcacgcgcc caagaccaag ctgttttctg agttgcttga tgagctagga
    13201 attggtaata ccaagcagac aagtcctgtg gtttgaccac aaatttgtcc ttccaagaag
    13261 taatcaagtt ttggatatta tccgcatctg tactgtatgc aagagctgct gccaactggc
    13321 gtttaaagac agcatctgtt gcgtgagtat aagtatcaag ataaagtgct aacaagtctt
    13381 tagtctcatg atgtttcatc tcattaatca gaacttgtga acgaatagct gctgggagtc
    13441 ctgcaagatt ctccttgtgt gttgcgaaga tttggctagc gacttgacta gcttctgcat
    13501 catttgagcg aatcatcatc gaaacagcca gctgacgaac caattcatcc tcatctgatt
    13561 ctccgtcttt agcttcaaaa ccaagacggt catagttatg acgagccaat ttagcaacca
    13621 gtcctttgaa ggctgtttca gcatccgttc cttcatcaat aaagcgctca agggctgaaa
    13681 tcacttgaga aacagctgaa accaccagat aagactcttc cttagcaagt ttatcaagaa
    13741 ctggaagcaa gtctgcataa gaaatgtgcc ctgcctcagc caacaaacga cgttcttgaa
    13801 caatttgcag tttgcttgtg ttatcaagtg tctctagctc agcaagaaca gcttctaaca
    13861 agtctccttg atagtcggta atatagtggg cagtattttc agtgttgaga cgaagagctc
    13921 cttcattttc agcaagaaga gctgcgtagc cagggatttc gatactttca gtttcgagtg
    13981 tatcaggcaa gcctttccag ttgctattga ggggcaccac ccagagacgg ttcttgtctt
    14041 cgttctcacc gatgaagaat tgtttttgtg aaatcttcaa gacatcattt tcaactttaa
    14101 cagtaagaac tgggtaacca ggctgttcca accaagaatc catgaaggct gcgacatcac
    14161 gtcctgacgc ttgaccaagg gcatcccaaa ggtcactacc aatggtgttg ctgtattggt
    14221 gtttttcaaa gtaggcgtgc aaacctttag caaaatcagc atctcctagc caacggcgaa
    14281 gcatgtgcat gagacggctt cctttggcat agacgatagc gccgtcaaag agtgtattga
    14341 tttcatctgg atgtttaact tcgacgtgga cagactgaac gccatcagta gcgtcacgtt
    14401 caagagcaag aggtactcca cctgtttgga aatcttcaaa gatattccag cttggttcga
    14461 tggtatccac acagacgtat tccatcatat tagcgaaact ttcattgagc caaaggtcat
    14521 cccaccattt catagtcacg aggttcccaa accattggtg agccaattca tgggccacaa
    14581 caagggcaac ttgttgacgg ctagcaaatg tagagttctc atcgacaacc aagtaaactt
    14641 cacggtaggt cacaagaccc cagttttcca tagcaccagc tgagaagtca ggaagggcga
    14701 tgtggagaga ttgaggaatt gggtacttaa ctccatagta atcttcgtaa aactcgatag
    14761 agcgaacagc gatatccagt gagaaatcaa gatttgaaag tggatgtgct ttggttgagt
    14821 agacacctac cagggtacca tttttagttt tagcggtcac cccttgcaaa tcaccagcaa
    14881 caaaggccaa caagtaagaa gacatgcgag gtgttgtctc aaacttccag atacctgttt
    14941 ccttacggtt ttcaacatcg atttctggca tgtttgacaa ggccaattca ccttctgctt
    15001 ggtcaaagcg aagagagagg tcaaaagttg ctttggcttc aggctcatcc acacatggga
    15061 aagcttcgcg cgcaaaatgg ctctcgaact gagtagacaa gacctccttc ttgactccat
    15121 caactgtata ataagaaggg taaatccctg tcatgttgtc tgtaatttta ccagaaaagg
    15181 caagaaccaa ttcaacttga ccagcctcag ccaattcgat atgaagggct tcattgtcat
    15241 ggtcaactgt aaatggacga gcttgacctg caacttctac agaggtgatt tccaaatctt
    15301 tttggtggag ggagatgcgg tcactctgtg cttgaccagt gatggtcact ttcccagaaa
    15361 aagtcttggt ctcacgactc aaatctaaaa ataaatcata atgttcagga acaaattgct
    15421 taataaaatg ttcaactgct tgcatagttt tctcctattc taagtttaag agctgctgct
    15481 cttcttcaaa caaacttatt atatcatatt ttgcttgaga aaaaaggatt ggacagcgat
    15541 ttccaaaact ttcttccttc taatagtcta cagtgggtag accttgcgaa attcttctaa
    15601 aacaaccttg ctttcaggtg taaaagtcaa tcctgcttca cccaagcagt ctctgaaaaa
    15661 atcctcatga acctggcgcc aatagacaag tgtcttgttt ccctcacctt ccttataggc
    15721 atggtcagct gacactcgat tgaagggttt aacagaaacc tttgtaattt cgacaatgca
    15781 gacagcctga ttttgactat ctaaaatgac atcgaaggtc cctacttggg gaagtggttc
    15841 gtcttctagt acatagaggt cataggctga tgctgttgct gtcttttctc ctttaaacac
    15901 caaatccgct aaaaggtctg gttcaactcc aaaagcccag gcatcgattt catctccgat
    15961 agaaggattg atttgtttgt atttattcca catttcttgc ggtatcatgg gtactccttt
    16021 gtaatttttt actttcttct tttatgtgtt taagatgatc tggatggtca atctctaaat
    16081 caaaaatctc tggaatagaa ctgtagtgga taatgcactt gatacccaac tgattcattt
    16141 tttgtatgaa agaagtattc agatagcctg ctacagcaaa attaatcttg ttctttcttg
    16201 ctttatcctg catatctctt agcatatcta acattattgg actttccata tcatgccatt
    16261 gactgtttct catagtcgca aaaacaaagg aagtcaaatc attcattcca actacaatct
    16321 ttgaaatgcc cgtttccagt atactagata agtcaaaata cgctgacggt aattcaatca
    16381 tcgttccgac tttcccagta aaaccctgct gacgcaatac tgtaatagct tgttttaatt
    16441 ggtcgtcatc attgacaaaa ggaaagataa cagatagatt ggggttggtt tgataaactt
    16501 ctgtaacgac atgtgcttca gcctgaaatt catccaaaca cgccagtaaa cgcctggttc
    16561 ctctatagcc aaacaaggga tgcccttcgt caaaaaactc tctagtcccc actaaacaat
    16621 tggcttctgt attcgttaat tcagaaaaac gataccaaac ttcttcatct gagtacaggg
    16681 agcagatagt ctctagataa tcttttacaa attgctgaca acttgctaat atgatgtttt
    16741 gattaagctc tctcaacaaa tattccccac gaatcatgcc gacgtggtga aatagttgag
    16801 gataaatttt ttcaagaatt ttttcgccac taagggcaag ttgatttctc atcattcacc
    16861 ttccaattca tgtaagaagt cttgtccagt tctggaaatc ctaataattc agacttaacc
    16921 ttcaagacta atggcgatgc attttcttct gtaatttctt gaatatccat ccaaatatat
    16981 ccaagtgaat cattcgcacc atcagacaca gcttccgaag tcgtaacttg aggtgcactc
    17041 tcattcattt caacatcata caaggccatg acatggtgaa ccataaaatt ttttaactct
    17101 tctctgacga aaacatcgta gattcgagga ttagagtagc ttctaacagt aaatctcgtc
    17161 tcttccataa cttctctagt cagcgtttcc gtcagtcctt caccaagttg ctgactgcct
    17221 ccaggtagat cataccgatg ttgataaggg cctctcgttt tttcaatgca aagtaacttt
    17281 ccattttcaa agcaaacaca gtagacccca aagtgttttt tgatttccat ccaactcctc
    17341 ctacttcaaa gaccagccac catctattgt caagatttgt ccttgcatgg cgctcgcttt
    17401 tccacttgct aaaaaaagac taagctctgc tatttcctct ggctcaatcc agcgcttgat
    17461 tggggtttca ctagccaccc agtcagccaa accacctggt tcaaaatccg cagcggtcat
    17521 agctgtcttg actgctcctg gagcgatacc aaagacctga atcccagctt cagcatagtc
    17581 tagagccaac tgcttggtga agccagccaa ggcatgcttg gatgaagtat aggcgtgacc
    17641 acctccacct gctaggctag aagcaatgga acacatattg atgatgattc cctttttatt
    17701 ttccagcatt tgtgtcaaat aataccgagt caactctact ggaataatgt agttgatttc
    17761 aaaaatctct tgaatgtcct gcgccgtttg ttccaacagt ggtttgtaat catccaaaac
    17821 tccggcagta ttacacaaaa catccacctg agggcaccag tcaaaaatag gttccaagtc
    17881 caaggtcaaa tctctctgta aaaagtgaaa atcaccctct aagagtggct tttcaccttg
    17941 gtcaactcca taaacttgat agcccttctc taaaaagagg cgagcttgag ccaatccgat
    18001 ccctgaactc actcctgtaa tgagtacacg tttagtcatg cacttctacc caatccgttg
    18061 ccaaaacatc acaagctgtc gggctccaca tggaaaaacc ttctccttct ccagacacgt
    18121 tgattaggaa ataaggtgtc acttcaagtg caagcccatt ttgctcgatg gtatcaaaga
    18181 gttggacata gttttccgca cctccccaac cagttcgtac atattttttc ttagccttta
    18241 agccaggtaa aatttcttca aatgtcatgt ttttctcctt taatgtcaat aattctcccc
    18301 ttcattataa caaaaaaacc gctttaaaac ggctttttga ctgtgattta ttcaaacctg
    18361 ctactactta cggcaaatta ttccctgcag caagataaat ttcataccat tcttttcttg
    18421 ttaagctaaa gtttgccgct cggctaactt ctctcaagtg cttaggattt gttgtaccta
    18481 cgactgcctg catttttgct ggataacgca atatccaaga aatggcaata gttgaagagg
    18541 ttactccata tttaatagct aaacgatcaa gtacttgatt taaagcttga aatttctcat
    18601 ttccaacaaa gttcccttta aaatacccga attgcaagac agaccatgct tgaatgacca
    18661 catcgtgtaa tttgcaatat tcaaaaatgc tgccatctcg catagctgct tgactatctt
    18721 ccatattaac atgaaaagct gattcaaatc ctggagtaaa agccgcactc aattgtagct
    18781 gattaacagc taacggctgc ttgacatctt ttttaagcaa ctccatcatc ataggatttt
    18841 gattagaaac tccaaaatct cgaactttac cttgtttata aaggagatca aaggcttctg
    18901 ctacttggtc agattccatc aaagcatctg gtcgatgaag gagcaagcta tctagatgat
    18961 caatcttcaa tctttgcaaa ataccgtcta ctgattttat aatatagtcc ttagaaaaat
    19021 caaaataggt aaattcttca atgcgaatgc cacatttgga ctgaatccac atcttttctc
    19081 ttaaatctgg acgatttttt aggacaagac ctaacagttc ttcacaacga ccacgaccat
    19141 aaatatcagc caagtcgaag gcattgattc caacagaaag tgctgtttct acaagctctt
    19201 caacttcttt tacagactta tcttttattc tcatcattcc gagaacaatt tctgataatt
    19261 ctttgtcatc ttgaccaaga gttatgtatc tcatcaaatt tttctccttt aatttctaac
    19321 attcttccct tcattataac aaaaaaccgc tttgcaacgg ctttttgact atacttcact
    19381 ccattttatc ttcttaaacc cacggaacaa gacaaagatt ccaataaaga ggacagctaa
    19441 aggaataact tttgtaagga aaacatttga aattcccatc cactcataat aacggagcag
    19501 agaacccacc acaagatggg caataatcat actgacaaat ggacgaaaga ccgcttcttt
    19561 ccaattccaa ataccgataa ctagcgaaat cgtaaagaca gacaaactat cccagggagc
    19621 cggaatataa aaggctcctt cttgtatgaa gcttgccatt cctacatatc ctaaaacaac
    19681 tagaagaact atagtcccaa caacaatgta agtgccaatt ttcattttag gagaatcttg
    19741 gactaaactt cttcgtaaaa ttgtggccac aagtccaaat ccaatcagaa aaataagaag
    19801 ttgccctaaa aatgtgagca aattgactgt taagagagga cctttagaaa aatcacttag
    19861 tagttgataa taacgtaata ccgccaggac aagaattggc gtcaaaaggg actctttgat
    19921 agaactgcga ggtgctccct tgagaatctc tttcattatt tttttaggat tcttacctag
    19981 ataatcctct gcactcatgc catctcgttc tgcttctgag aaatctagca tcatcaaata
    20041 gatctgctct ctgagatagt cttcatcata gagaaatcca gcaagattaa aactttccca
    20101 caactcctca aaatactttt gattctcctc agaaaactca tgtagcaaag cgcttgtttc
    20161 ttcgtaatac ttcattttct tcatggttta acccccattc ttaatccctt ctactttttg
    20221 actcaaatcg tcccattgtt gccaaaagac tgagacacgc tcttctcctt ctttcattaa
    20281 tgaaaaatac ttccgatctg gaccatctgg cgacgggcgc atgtcgcctc ttatccattg
    20341 atttttttct aacttttgca acaaaggata aatagttcct ggaacgatag tatcaaatcc
    20401 agcctctcgc aaagtctgaa ccaactcata accataccgc tctttttgac caatcatatc
    20461 caagacacaa ccttcaagaa caccttttaa tagctgagtt tctttcatca cttctccctt
    20521 ctaatctatt ttgtaatacc tactagtaac ttcacctata gtatatcact tctacactag
    20581 tttgtaaagc ataatagtta atactcttcg aaaatctctt caaaccacgt cagcgtcgcc
    20641 ctaccgtatg tagggttact gacttcgtca gtttcatcta caacctcaaa act
//
LOCUS       DBERDS010000032        20595 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.032, whole genome shotgun sequence.
ACCESSION   DBERDS010000032 DBERDS010000000
VERSION     DBERDS010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.032"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            74..193
                     /locus_tag="ACL73E_001374"
     CDS             74..193
                     /locus_tag="ACL73E_001374"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0801334.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLI"
     gene            212..1396
                     /locus_tag="ACL73E_001375"
     CDS             212..1396
                     /locus_tag="ACL73E_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0801335.1"
                     /translation="MLISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAY
                     RLSEGYGTDGPSAGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSL
                     FMAITIGLVTAEIYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGL
                     EAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDP
                     VWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKT
                     LGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTG
                     VILPWTMPPIIGGFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVG
                     GK"
     gene            1398..3284
                     /locus_tag="ACL73E_001376"
     CDS             1398..3284
                     /locus_tag="ACL73E_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HGS0801336.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            3452..3796
                     /locus_tag="ACL73E_001377"
     CDS             3452..3796
                     /locus_tag="ACL73E_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0801337.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            3806..5218
                     /gene="lacG"
                     /locus_tag="ACL73E_001378"
     CDS             3806..5218
                     /gene="lacG"
                     /locus_tag="ACL73E_001378"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS0801338.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            5288..6967
                     /locus_tag="ACL73E_001379"
     CDS             5288..6967
                     /locus_tag="ACL73E_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS0801339.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(7093..8532)
                     /locus_tag="ACL73E_001380"
     CDS             complement(7093..8532)
                     /locus_tag="ACL73E_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGS0801340.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(8536..9885)
                     /gene="trkA"
                     /locus_tag="ACL73E_001381"
     CDS             complement(8536..9885)
                     /gene="trkA"
                     /locus_tag="ACL73E_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGS0801341.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            10074..10922
                     /locus_tag="ACL73E_001382"
     CDS             10074..10922
                     /locus_tag="ACL73E_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGS0801342.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10937..11485
                     /locus_tag="ACL73E_001383"
     CDS             10937..11485
                     /locus_tag="ACL73E_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGS0801343.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            11492..11704
                     /locus_tag="ACL73E_001384"
     CDS             11492..11704
                     /locus_tag="ACL73E_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002668516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801344.1"
                     /translation="MKIKEQTRKQVAGCSKQCFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            11806..13488
                     /locus_tag="ACL73E_001385"
     CDS             11806..13488
                     /locus_tag="ACL73E_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801345.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            13473..14303
                     /locus_tag="ACL73E_001386"
     CDS             13473..14303
                     /locus_tag="ACL73E_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0801346.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            14496..14999
                     /locus_tag="ACL73E_001387"
     CDS             14496..14999
                     /locus_tag="ACL73E_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGS0801347.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      15053..15287
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            15452..16015
                     /locus_tag="ACL73E_001388"
     CDS             15452..16015
                     /locus_tag="ACL73E_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0801348.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            16005..16655
                     /locus_tag="ACL73E_001389"
     CDS             16005..16655
                     /locus_tag="ACL73E_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS0801349.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            16683..17072
                     /locus_tag="ACL73E_001390"
     CDS             16683..17072
                     /locus_tag="ACL73E_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGS0801350.1"
                     /translation="MKVNIADLHLTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            17077..17526
                     /locus_tag="ACL73E_001391"
     CDS             17077..17526
                     /locus_tag="ACL73E_001391"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801351.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKKIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            17654..18241
                     /gene="rpoE"
                     /locus_tag="ACL73E_001392"
     CDS             17654..18241
                     /gene="rpoE"
                     /locus_tag="ACL73E_001392"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGS0801352.1"
                     /translation="MKLEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVTPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            18631..20238
                     /locus_tag="ACL73E_001393"
     CDS             18631..20238
                     /locus_tag="ACL73E_001393"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGS0801353.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6104 a         3540 c         4580 g         6371 t
ORIGIN      
        1 aaaaaatata ttgacaacgc tttctgttag tggtatattt aatttataaa aaataaaaaa
       61 aggagttccg gtgatgaaca atattttagc gtttttagaa acaaaagtcg ctccgtttgg
      121 tgaaaaagtt ggcaaccaac ggcatttgaa agctattcgt gaaggattta tgatggcaat
      181 gcctttgatt tgagtcggat ctttatttct tattctaatc agttggcctc aagaggattt
      241 tacaaattgg ctgaatagtg ttggattgct aagtatcttg acaactatga atcagtcaac
      301 agtagcgatt atctccttgg tcgcttgttt cggtattgcc tacaggttgt cggaaggata
      361 tggtacagat ggtccgtcgg cagggatcat agccttatcc agttttgtat tgatggcacc
      421 tcgtttttcg agtatggttt atgataaaaa tggggagcag gtcaagcagt tatttggcgg
      481 cgcaatacca ttttctagcc tgaatgcatc ttctttgttt atggcgatta ctattggatt
      541 ggttacagca gagatttatc gtatgtttat ccagcgcgga attacgataa aaatgccaag
      601 tggtgtccca gatgtggtaa gtaaatcatt ttcagctctt ttacctggct ttactacttt
      661 tgttttgtgg gctctggtct taaaaggtct tgaagcggca ggagttgcag gaggtctcaa
      721 cggactccta ggtgcaattg ttggaacacc gcttaagtta attgcaggaa cgcttccagg
      781 tatgattcta tgtgttattg taaactcatt cttttggttc tgtggagtta atgggggaca
      841 agttttaaat gcttttgtag atccagtttg gttacaattt actacagaaa accaagaagc
      901 tgtggctgca ggacaaacac tccaacacat tattacatta ccgtttaaag atttatttgt
      961 atttattggt ggcggtggag cgactattgg tcttgcgatt tgtctcttcc tatttagtaa
     1021 gagtcgtgcg aataaaacat taggtaagct agctattata ccgtctattt ttaatatcaa
     1081 tacagctatt ctatttacgt ttccaacagt tttaaatccg attatgctga ttccgtttat
     1141 tgctactcct acaatcaatg ccttaattac ctatgtatca atggctgtag gattagtacc
     1201 ctacacaaca ggtgtaatcc ttccgtggac aatgccaccg atcataggag gcttccttgc
     1261 gacaggagct agttggcgag gagctctatt acaagttgtt ttgattttgg tttctgtagc
     1321 aatttattat ccattcttca aaattgcaga taaacgcaat cttgaaaaag aaaaagctac
     1381 tgttggaggg aaataagatg gttatcagag tatttgatca gcagaaaaat acttattcta
     1441 gctttgcctt agaggaatta agttactata taaatcgggt ctttaagact gacatagaac
     1501 ttgtcgagga gaaggaagcg gatatttttg taggattagt caataaagag gatagaaaag
     1561 accatgttct tatctcatta gacaagggta aggggagaat tgagtctaat acaattgtag
     1621 gtttacttat tggaatttac cgaatgtttc atgaatttgg ggttgtgtat actagaccag
     1681 ggcgcggaca tgactttgtt ccagagttac gatttgaaga ttttttagat aaagagctat
     1741 ctatagatga aacagccagt tactatcata ggggagtatg tatagaggga gcagattcat
     1801 ttgaaaatat actagatttc attgattggc tacctaagat tgggatgaac agttttttca
     1861 ttcagtttga aaatccctat tcttttttga aacgttggta tgaacatgag tttaatccat
     1921 acctaaataa agaaaaattc tcaaatgaat tagtacaaga attgagtgat aggttggata
     1981 aagaattgca aaaaagaggt cttattcatc atcgtgttgg tcatggatgg acaggtgagg
     2041 ttttaggtta ctcttcaaaa tttggctggg aatcaggtct tagtatttca gaggagaaga
     2101 aaccctatgt cgctgaaata aacgggaaac gagaattatt taatacggct ccgattttaa
     2161 ccagtctgga tttttcaaat ccagatgtgg cggataagat ggtagaaatt atcaaggatt
     2221 atgccaagaa aagacctgat gttaactact tacatgtatg gttgtcggat gctcgtaata
     2281 atatttgtga atgcgaaaac tgtagacaag aattggtttc ggatcagtat attcgtattc
     2341 tcaatcaatt ggatagggct ttaacgagtg agggattaga tacaaagatt tgttttctgc
     2401 tttaccatga gttgttatgg gcgcctcaga aagaaaaatt agataatcct gaacgcttta
     2461 ccatgatgtt tgcaccgatt acaagaacat ttgaaatgag ttatgcagat gtagattttg
     2521 acaattccat acctacgcct aaaccttatc tgcgtaataa aattatactt ccgaattctc
     2581 ttgaggaaaa tttatcttat ctttttgagt ggcaaaaaac atttaaagga gatagtttcg
     2641 tatatgacta tcctttaggg cgtgctcatt atggcgattt aggctatatg aaaattagtc
     2701 aaaccattta cagagatgta tcttatcttt ctaacctaca tttgaacggt tacatttcgt
     2761 gtcaagaatt acgtgccgga ttccctcata attttcctaa ttatgttatg ggggaaatgc
     2821 tctggaagaa gacaagaagt tatgaagaat tgattgaaga atacttttct gctttgtatg
     2881 ggtcaaattg gcagtctgtt gttgaatatt tagaaaaatt atccagttat tcctcatgtg
     2941 attattttaa tgcaattggc agtcgtcaaa atgatgtttt agcgaatcat tattatatag
     3001 cttacaatct agctgataat tttttgccaa ttattgagga aaatatttct aagttattaa
     3061 atagtcaaaa ggatgaatgg aaacagctca gttatcatcg tgaatatgtt gttaagatgg
     3121 cgaaggcttt atatcttcaa gcaaccggaa aaacaaggca agctcaagat gaatggagaa
     3181 atgtgttgaa ttatatccgt gggcacgaat tgctatttca atctaatttg gatgtttatc
     3241 gtgtaattga agtagcaaaa aattacgctg gtttccactt ataaatcata agtatagaaa
     3301 atgaaccaag gtattcagag aagattgatc ctaaatatta tgaaatttaa ggatttttaa
     3361 gatatttagg gtcgactttc tatttatatc gtagcgaagt cattttaata atgatgtgta
     3421 aaagatggat caagattgag gaggaagaaa gatgaaatca aaagaagaaa taaatatgct
     3481 tggttttaca attgtcgctt acgcaggaga tgcaaggtca gatttgatgg atgctttggc
     3541 gtttgcgaga gatggatatt ttgaacaggc aagagaattg gttgagtctg caaacgactc
     3601 aatagtgtct gcccatcgag aacagactaa tttattagcg gaggaggcat ctggagataa
     3661 ttttgaagtg agttttatca tgattcatgg tcaagatacc ttgatgacaa cgatgctatt
     3721 gtatgatcag gtcaagtttt ttattgatga atatgaacga attcgaaaga ttgaagaaca
     3781 tattggtttg caatgaggat tagtcatgga aaatttacag gttaaagcct taccgaagga
     3841 gtttttatta ggagctgcta ccgctgctta tcaagtagag ggtgcaacta gggtagatgg
     3901 caaaggaaca aatatgtggg atgtttattt gcaagaaaac agtccgttct taccagatcc
     3961 agctagtgat ttttattatc gttacgaaga ggatataact ttggcggcag aacatggttt
     4021 gcaggctttg cgtttatcta tttcttgggt tcgtatattt cctgatatag atggggagcc
     4081 taatatatta gctgttcgtt attaccatag agtctttcag tcttgcttaa aacataatgt
     4141 gattccgttt gtttctttac atcattttga ttcgcctcag aaaatgttag aaacagggga
     4201 ttggttgaat agagagaata ttgatcgttt catacgatat gctcgctttt gtttccaaga
     4261 atttacagaa gtcaagcatt ggtttacaat caatgaactg atgtctcttg ctgcaggtca
     4321 atatatagga ggtcagtttc ctccaaatca tcattttcaa ttatctgaag caattcaagc
     4381 gaatcataat atgttgttgg cgcatgctct tgcagtcctc gaatttcatc aattaggaat
     4441 tgagggagag ataggttgta ttcatgcttt aaagccaggc tatcctattg atgggcaaaa
     4501 agaaaatatt ttggcagcta aacggtatga tgtttataat aataaatttc tattagatgg
     4561 aacttttttg ggctactaca gtgaggacac gctttttcac ttgaatcaaa tattggaagc
     4621 taataattct agctttatta ttgaagatgg tgatttagaa attatgaaga gagctgcagc
     4681 tcttaatacg atgtttggga tgaattatta tcgttcagaa tttattcgtg aatacaaagg
     4741 tgaaaataga caagaattta attcaacagg aataaaagga cagtcttctt ttaaattaaa
     4801 tgctctaggt gaatttgtaa aaaaacctgg tattccgaca acagattggg attggaatat
     4861 ttatcctcaa gggttatttg atatgttgct tcgtatcaaa gaagaatatc ctcaacatcc
     4921 ggtcatttat ttaactgaaa atggtacagc ccttaaagaa gttaagccag agggcgagaa
     4981 tgatattatt gatgacagta agagaatccg ttatattgag caacatttac acaaagtttt
     5041 agaggctcga gatagaggag tcaatattca aggctatttt atatggtctt tgcaagatca
     5101 attttcttgg gcgaatggct acaataagcg atatggtctt ttctttgttg attatgaaac
     5161 acagaagaga tatattaaga aaagtgctct ttgggtaaaa gggctaaaac ggaattaagg
     5221 ttagcgattt gactgatgtt taatatattt taactatgag cttaaatttt ttacaggagg
     5281 agtttttatg gataagttag tcgctgccat tgaaaagcaa caagggaaat ttgaaaaaat
     5341 ttctactaat aattatatga tagctattaa agatggattt attgctacta tgcctttaat
     5401 tatgttttca agctttttga tgattattat tatgattcct aaaaatttcg gagtagagtt
     5461 accgagtcca gctattgcct ggatgaggaa agtgtatatg ctaaccatgg gagttttggg
     5521 tattattgtt tcagggacag ttgcaaagtc attggctgga aatgttaata gaaaaatgcc
     5581 tcctggaaag gtaataaatg atacttctgc aatgttggcg gccatatgtg gctatcttgt
     5641 attaactgta acgcttgtag ttgatgagaa aacgggatct acaagtttgt cgacaaacta
     5701 tttaggatct caaggattga taacttcgtt tgtcagtgcc tttattactg taaatgttta
     5761 ccgattctgt attaagcgag acattactat tcatttacct aaggaagttc ctggggctat
     5821 atcacaagct tttagagata tttttccttt ttcttttgtt ttacttatta gtggtttgtt
     5881 agatattgta tctcggttta gtttagatgt tccttttgcc caagtatttc aacaactatt
     5941 gactcctatt tttaaggggg cagaatcata tcctgctatg atgttgattt ggtttatgtg
     6001 tgctttgctt tggtttgttg gaattcatgg accatctatt gtcttacctg ctgttacagc
     6061 tttacaactg agcaatatgg aagagaatgc tcaacttctt gcaaatgggc agttccctta
     6121 tcattcttta acacctaatt tcgggaatta tatcgctgct attggaggaa cgggggctac
     6181 ctttgttgta ccatttattt tgattttctt tatgcggtct aaacaattaa aatcggtagg
     6241 taaagctaca attactcctg ttttatttgc ggtaaatgaa cctcttctat ttggtatgcc
     6301 tgttattttg aatccctatc tttttgtccc ttttttgatg actccaccag tgaatgtatt
     6361 tctaggaaag gtatttattg atttctttgg aatgaatgga ttttatatcc agttaccttg
     6421 ggcctttcct ggtcccttgg gattgttaat tggaacgaat tttcaactta tctcctttgt
     6481 atttttatct ttgatgttag ttgtcgacat attgatttat ttgccattct gtagagcgta
     6541 tgatagacag ttactggtga aagaagatat tgcaagctca aatgatatta ttttagagga
     6601 ggatacaagt gaaataatgc ctggtgagat agatgtaata aaaagtaagg agttgaaagt
     6661 actggttctt tgtgcagggt ctggaacaag tgcgcaatta gccaatgcaa ttaacgaggg
     6721 cgctcaatta gcagaagtta gagtgattgc gaattcagga gcgtacggag ctcattatga
     6781 tattatgggt gtttatgatt taattattct ggccccacaa gttcggagtt attatagaga
     6841 gatgaaggtg gatgcagaaa gattagatat tcagatagtt gctaccagag gaatggaata
     6901 tattcattta acaaagagtc caagtaaagc cttacaattt gtattggagc attaccaagc
     6961 tgtgtagtaa gtttttccat cttttatttg agtaaagatt ttgcttacag ataggcttgg
     7021 atttaaaaac gttccccctt ttttaatata agaatccctc tttcacaatt gtaaaaagag
     7081 ggattttgta ttttatctct tagaccaagt tctcttcata aagagaagga ggattgggta
     7141 aatctccaag cgccctgcaa tcattgcaaa ggataggaga atttttgaga tgggactaaa
     7201 gattgagaaa ctagaagtgg ttcctagaat aggcccgata ttattgaaac agctaaagac
     7261 agcgctggtc acgaccagaa aatcattgct atctaggctg acaataaaga taagcgctag
     7321 caaaatcata gcatagatga caaagtactt gagaatctta tgctgggtat ctttgtcaat
     7381 caccgtttta ttaacatgga gggtcaaaac acggtggggc gataggattg acaaaatttg
     7441 gtttttggca atttttgaaa ggatgaggcc tcgaataatc ttgagtccac ctgcagttga
     7501 tccagcagag ccaccgattg ccatgaggaa aaggaggata aactgggaga agaggggcca
     7561 gttggtaata tctccatatc caaaaccagt tgttgtaatg atgttggaaa cctggaagaa
     7621 ggtcatttca aagctctttg aaaaccctgg gtagaggtag agggtgttga ggctaatcaa
     7681 gcctgtagaa accagtacaa tgaccaagta agccctaagc tcttcatctc caaagaaggc
     7741 cttgatgcga cggagcatga ggtagtagta gaggttgaaa tttactccaa aaaccagaac
     7801 tccgatactg accagatagg taatcagtga gctgccatag tgggcaattc cgtcgttata
     7861 gacggtaaag cctccagttc ccgctgtccc catagcaata acaaaactat cgtagagagg
     7921 cataccggct agataataga tgatgacaaa gagggagaag agagctagat aaaggagata
     7981 gagaatctgg gcagtgtttt ttagtttgga tacaaccttg ccaaaaacag gacctggaac
     8041 ctcagccttc atcacctcta ggtggctatt tttggcattg tccataatag caagtgcaaa
     8101 aacaagcact cccatccctc caatcaagtg ggtaaaactt cgccagaaga ggagggaacg
     8161 gctgagaacc gaaacgtcgt tcaaaatact tgctccagta gttgtaaatc cagaactaat
     8221 ttcaaaaaag gcatcaataa ggctggggat ttgcccagaa aagacaaagg ggagaccacc
     8281 aaagaaagac caaaggatcc aacagagggc aacgatcaag actccctcct tggcataaat
     8341 ccgttgattt tttggcttct gtaaactccc tgaaccgcct aacaatacga gaatccctat
     8401 ggtcgaaaag agggctgtaa agacttggct cgattcacgg taatagacag caatcgcaac
     8461 aggaaccaaa agaagaacag cttcaatcaa aagtaatttt gaaaggaggt aacgaatcat
     8521 acttttattc atttcttacc tcgcgatcaa gtcataaatc ttggtgatgt ttggcaacaa
     8581 ggttgttact aggagcttgt ctccaacttc caacatatcc tccccagttg ggaaaatagt
     8641 cttgcccttt cgaataatgg ctgcaataag aacccctttt tttaatttca gttgagaaag
     8701 aggtttggca gtcattttat tggcttcctt gatatggaat tgcagggttt cgatttggcc
     8761 attggctaga tggtgcatgg cttgaaggtc tgaatactgg gcattaactc gaccacgaat
     8821 aaagtgcata atcgtatcta cagcgatgct tttaggtgtg atgatacttg aaaaatcagg
     8881 cgcattgata atctcgagga gactggtacg attgacctta gtaatatttt tctgtacacc
     8941 taccctgtca aggaacatag atgtaatcag attttcctca tcgacacctg ttagagtcgc
     9001 aacggcatca tagtgttgag cactttcttc cagcaggata tcttttgcgg ttccatctcc
     9061 ttgaacgatg tagagatttg ggaatttctc gctaaagaag ctggcgattt caggattgat
     9121 ttcaatgact tttgtatcga tacgactatc tttgagaata ccaagtagat aataggcaat
     9181 tctacctgcc ccaacgatga gaaggctctt cacggcgcgt gatttaaaat aattatggaa
     9241 gagtatcata tcgacacggt taccagtgac aaagattcta tctttatcct gtacagtcat
     9301 gtcaccgctt ggaatgataa tttgatgatc cctctctatc gcacagacaa tgacattacc
     9361 aaatttttta cgaaaatcag aaatgggcat ttggcaaaga ccgctggtgg acttgacgac
     9421 aaattccatg aggctaacgc gtccaccagc aaagcgttcg acagacaggg cgttggggaa
     9481 gtcaatgata ttcgcgatag cgcgggcagc caagagctca ggattaacga taagagaaaa
     9541 accgagaata ttcttttcct tgaaataaga gttagaatat tcagggttcc gcacccgaac
     9601 gatagtttct ttagctccca ttttcttggc tagaactgct gcaatcatgt tgacttcatc
     9661 gtgctcagtc agggcgataa agatatcaca atcttggacg ctggcttgct caagaatggc
     9721 aaaatcggcc ccgttaccaa ggataccaat gatatcaaag cgactgacaa tatgattgag
     9781 aacagcttcg tcttgctcaa tcagcaaaac atcatgcttt tctgcaacca aggagcgaca
     9841 gagggcaaaa ccaacttttc cccctccgac aaggataatt ttcataataa aacctacttt
     9901 ttcatgatgt aactatcata ccctttttca agaaaaaatg cacctactag ctaataacca
     9961 gagtttttag taggaaattt gctataagtt aaaactatac cctaaccaat tgaaatagct
    10021 attagcgact ttctctgaaa tatggtatga taaaggatat acaaggagat aaaatgaata
    10081 ataatttact ggtattacaa tcagactttg gtctggttga tggtgcggta tcggctatga
    10141 ttggagtggc tttagaagag tctccaacct taaaaatcca tcacttgacg cacgatatca
    10201 cgccttataa tatttttgag gggagctatc gtctctttca gacggtggat tactggcctg
    10261 agggaacgac gtttgtatcg gttgtcgatc caggtgtcgg ttcgaaacgt aagagtgtag
    10321 ttgccaagac tgcaaaaaat caatacattg tcacgccaga taatgggacg ctttccttta
    10381 tcaagaaaca cgttggcatt gtagccattc gtgagatttc tgaggtggcc aataggcgtc
    10441 aaaacacaga gcattcttat accttccacg gtcgtgatgt ctatgcctat actggtgcta
    10501 aactggccag tggtcacatt acttttgagg aagtagggcc agagctcagt gtggaacaga
    10561 ttgtagagct tccagtcgta gcgaccatca tagaagatca tctggtgaag ggagccattg
    10621 atattctgga tgtgcgtttc ggttcgcttt ggacctctat cacacgggaa gaattttaca
    10681 agttggaacc agaatttggt gatcgttttg aagtgaccat ctatcatgct gatatgctgg
    10741 tctatcaaaa tcaggttgtc tatggcaaat catttgcaga tgtgagaatt gggcaaccca
    10801 ttctttacat caactctctc tatcgtttag gtttggctat caaccaaggt tcctttgcca
    10861 aggcctataa tgtaggtgtc ggttcatctt ggaccattga aataaagaaa atagaaggat
    10921 aaaataggag aatagtatgg aaatcaaatt tacaattaaa caagttgttg ctgtcggaat
    10981 tggcgctgcc ctctttgtcg tcatcgggat gatcaacatt ccaacccctg ttccaaatac
    11041 aagcatccag cttcagtatg cggtacaagc gctactttct attatttttg gaccgattat
    11101 cggtttgctt gttgggttga ttggtcatgc aatcaaggac tctcttgttg gttatggtct
    11161 atggtggact tggattatcg ctagcggact ctttggttta gttgtgggac tttttagaaa
    11221 gtacgttcgc gtgatcaatg gtgtttttga ctggaaagat attcttattt ttaacctcat
    11281 tcaactactt gcaaatgccc ttgtttgggg tgtcttggca ccacttggag atgttgtgat
    11341 ttatcaagaa gcggcagaaa aagtatttgc acaaggaatt gttgcgggaa ttgccaatgg
    11401 tgtatctgta gctattgcag gaactcttct cttacttgcc tatgcaggaa ctcaaactcg
    11461 tgcaggaagt ttgaaaaagg actaatactc aatgaaaatc aaagagcaaa ctaggaagca
    11521 agtcgcaggt tgctcaaaac agtgttttga ggttgtagat gaaactgacg aagtcagtaa
    11581 ccatacctac ggcaaggcga agctgacgtg gtttgaagag attttcgaag agtataaaat
    11641 gatggggaag gctgggcaac tagtcttttt cgatgtttat agattagtta ggcaagtaag
    11701 ctaggatagg aatctttttg gcgctaagat tttaagagaa gagactgcaa gaagggcttg
    11761 atttatgata aaatagaagt ctaagaagcg aatgaagaga gtaagatgaa agaagctata
    11821 attgagtgga aggatttctc tttccggtat gaaacacaac aagaaccgac cttgcaaggg
    11881 atagacttga ccatttacaa gggagagaaa gtcttaattg ttggaccatc tggatcaggt
    11941 aaatctacct tgggtcagtg tttgaatggg attattccca atatttacaa gggtcagaca
    12001 tatggagaat ttttgataaa gggtcaaaca gcctttgata tgagcatcta tgataagtct
    12061 catctggtta gcacagtttt gcaggataca gatgggcagt ttattggctt gtctgtggca
    12121 gaagatttgg cgtttgctct ggaaaatgat gtgacagccc tagatgagat gaaaggtcgt
    12181 gtttataaat gggctgaaaa gctggacctt cttcctttac tggatcagcg ccctcaggat
    12241 ttgtcaggtg gacaaaagca gcgagtcagt ctggctggtg tcttgattga tgaaagtccg
    12301 attctcttgt ttgatgagcc actcgccaat ctagatccca agtcaggtca ggatattatc
    12361 gaattgattg accagattca taaggaagag gggacgacga ctctgattat cgagcaccgt
    12421 ttggaggacg ttctgcatcg ccctgtggat cggattgtct tgataaacga tggtcgtatc
    12481 ctttttaatg ggagccctga ccagttgctt gcgactgatt tattgactca aaatggaatt
    12541 cgagaacccc tttatctaac gactctccgt caattaggtg tggacttagt caaggaagaa
    12601 caattagcag atctggataa cttgtctatc tcaaaagggc aagtccagtt acagacggaa
    12661 ctggtaaaag aaaccccaga attgcagtca ctctttagac tagaggaagt atctttttct
    12721 tatgatgata gaccgatttt aaaatcccta catttagata ttaaaaaggg tgaaaagatt
    12781 gctattgtcg gaaaaaatgg agcagggaaa tcaactctag ccaaggctat aagtagcttt
    12841 attcagacgg aaggacgcta tctttgggaa aaacaggata taaaaggcga ttctgttgca
    12901 gagcgggcgg aacgagtagg ctatgtgcta caaaatccta atcaaatgat ttcaaccaat
    12961 atgatttttg atgaggtggc tctagggctc cgtttgcgag gtgtggatga gaaggaaatt
    13021 gaaacgagag tctatgaaac cttgaaaatc tgtggacttt atgaattccg taattggcct
    13081 atttctgccc tgtcatttgg tcagaaaaaa cgtgtcacca ttgcttcaat tttggtctta
    13141 ggagctgaaa ttattctcct agatgaaccg actgcaggtc aagatcagaa gaactatact
    13201 gagattatgg aatttctcga agagttacat caaaaagggc ataccattgt catgattacc
    13261 catgatatgc aattgatgct ggattattca gaccgggtcc ttgtcatggt ggatggagaa
    13321 ttgattgccg atactgttcc agccagtctg ttgagcgatc ctgagctgtt agtaaaagcc
    13381 aatctaaaag aaacctccat ctttaacttg gctaagaaac tagatgtgga tccactggat
    13441 ttaacggcat tttacaaaga aaggagagag ggatgcaagc taaattaatc ggttaccagc
    13501 atagagatac tgtgattcat cgcttgtcag gagctgggaa acttctcttt ttcattctgg
    13561 tatcattggc ggccatgatt agctatgata ccagaatgct cttgctgatt gccatctttt
    13621 cagtctttct cctctattta tcagaaattc gctttaaaga tgtttccttt gtagccgttt
    13681 ttgcgacggt atttgccgtt ttaaacgttt tgatggtcta tctcttttct cccgagtatg
    13741 gggttggact ttatggagag agaagtgtga tttggcaggg aatcggtgtc tacactctaa
    13801 ccagccagga gctcttttat ctgctaaatt tggccattaa gtatctttgc accattcctc
    13861 tggctattat ctttttgatg acaacccatc ctagtcagtt tgcttccagt ttaaatcaaa
    13921 ttggtgtgcc ctataagatt gcttattctg tcagcctgac cttgcgctat attccagatt
    13981 tgcaggaaga attctttact atcaagatgt ctcaggaggc gcgtgggatg gaattatcca
    14041 agaaagcttc tcttatgcaa cgaatcaaag gcaatctgct cattattacg cccttgattt
    14101 ttagctcgct agaacgcatt gataccattg cgactgccat ggagcttcgc cgctttggga
    14161 aagagaaaaa acgcacatgg tatagttatc aggccttgaa aaaaggagac tatattacct
    14221 tgctcttggc aaccttgttt ttagtagtta gtttactact tatcttgcag aatcagggac
    14281 gattttacaa cccttggaaa tagcttgaaa aaattgaaaa aatcaagtcg tttctattga
    14341 caatgattct gaaagtgtta tactaagaaa gtagtttcgc tgatttactt caaacctgtt
    14401 gtgaggtaag ttaacgatgc cttaaccacg ctgtttgctg agcttgactc cgggcagtgt
    14461 ggctattttt ttgcaatggt gaaaggaagc aagtcatgac aaatcacatt gtattatttg
    14521 aacctcaaat tccacaaaat acgggcaata tcgcgcgtac ttgcgctgcg accaattctc
    14581 ccctccacat catcaagcct atgggctttc ctattgatga ccgcaagatg aagcgggctg
    14641 gattggatta ctgggataag ctagagattt atttttacga gagtttggaa gatttcatat
    14701 ctcagatgaa gggaaaactc tatctgattt cgaaattcgc ggaaaaagtc tattctgagg
    14761 tggatttatc gactgacgag gaccattatt ttctctttgg acgtgaagac aagggcttac
    14821 ctgaagattt tatgcgagaa catcctgaga aggctctccg tattcccatg aatgatgaac
    14881 atgtccgcag tctcaatgtg tctaataccg tctgcatgat tgtctatgag gctcttcgcc
    14941 agcagaactt tgcaggtctt gagctcgtcc atacctatga agtggataaa ttgaaataaa
    15001 aaatgaaaat gaacaaaatg cttgcgcttg caagcgtttt ttgttatgat aaaagagtct
    15061 tcagggcagg gtgtgattcc cgaccggcgg tgactttaac taggaaatga tcttttcctt
    15121 ttatactttg ttgacaagct ttgcctaacc agaagttatg cctacagctt gtcgcctagt
    15181 ctaaaagaaa aatctctatt tccttctctt taaagaagtc cgcgagcgca agctgatgtg
    15241 gtgagattcc acaaccgaca gtatagtctg gatgggagaa gacgaaagaa tagctttgtc
    15301 tgttttgata gatttatagc cggattgtaa ccacttgctt tgtttttctt taatagagta
    15361 agagggaact tttgggatat aaaaagtgag aatagataga ggaatccttt ccaacttctt
    15421 ctgattttat agaaaattgg aggaacctgt tatgacaaat acacgtcgac tttcgaccat
    15481 tgcaatttta tcagccatct catttgtgct gatgtacttt gactttccgc ttttaccagc
    15541 ggcatctttc ctcaagatcg aatttagtat cttgccagtc cttgtgggtc tggtggtcat
    15601 ggatttgcct gctgctctag gagtgctctt gcttcgctca ctcttgaaat tgcttcttaa
    15661 cagccaagga gtgaatactt acattggttt gccgatgaat atcgtagctt tgggagtttt
    15721 tgtcatcgta tttgctttga tttggaaaaa ggaacggaca acccttcgtt tcctactagg
    15781 ctctctagct ggaactgttg gtttaacctt ggccatgttg gttctcaact atgtttatgc
    15841 tgttcctttg tacgctaagt ttgctaactt tgatattgga aaaattttgg gactttccaa
    15901 ctacctaatg accatggtat taccttttaa cttgattgag ggtgtaatct tttccgtttc
    15961 attctggttg ttgtacgtcc ttttgaaacc aaccttaaaa cactatgaaa gataaacaaa
    16021 catttttaat gaagggcagt tttgcccttt tacttttcgt tattcttggc tatatggtca
    16081 aattttaccc tgaaatgttg gtcaattttg accaatcgat tcagactgcc attcgaggag
    16141 acttaccaga ttatttgact attctttttc gagccctcac acgtctgatt gatatcccag
    16201 tgattatcac ttgggttgtc attacagctt ttgtctttta tcgtaagcga tggaagatag
    16261 aaagtttctt catgctggga aatctggctt tggcaggtct tttaatcgtg acctttaaaa
    16321 atatctacca gcgcccacga ccagctatct tacatctggt ggaagagaag ggattttcct
    16381 tcccaagtgg gcattctctg gctgtaactt tgatggtagg tactctgatt gtcattctca
    16441 gtcaacgaat taaaaatcca gtctggagaa aaatcgtaca aatcgtcctt ggcctctacc
    16501 tagtcagtgt gctggtatca agagtctatc tgggagttca ttacccatca gacgtccttg
    16561 ccagtctctg tgtgggcttg ggagtcctgt ttatcgagtt tcccttctat gacaagctcc
    16621 gcttccaatg gcgatttaaa ggcaaacaga agtgagtatc gaattccctt gaggagaaag
    16681 aaatgaaagt caatatagca gatcttcatc tgactcaact atatttatca gaaaagaagt
    16741 tgcaagatat tcagatgctt taccagtcgg cagaaacaat ccaagtcgat ccaatcagta
    16801 ttcttgcctt tggagattgt ttgctgatta cagatgggca tcacagggct tatcaggctt
    16861 tattggcagg tcgggatacg atttctgctg agtgggatag agatggtggt gatgaactat
    16921 atcatctcta tgcgcaagct tgcgaggaaa gaaagattta ctctgttttt gatttagaag
    16981 atcgtatcct agctcaagat gggtatgaag caaaatggta taactggtgt gatggtttta
    17041 atcaagcagc aactcttttg ttgaaaaggt agtgcattgt gttttgttcc ttattataag
    17101 gtcaatcatt gtgaggaagc ttttgcttgg tatcaggatg tgaacttggt ttacctcgta
    17161 gatggggtga agcttcctta cagtcaagcg accttggaag ccatgtattc ctatttggat
    17221 cggcatggtg agcttttttg gattgaagtc aaggagaagg gagaatggtt tccaattggg
    17281 gatattacac tatctcagga taatctcccc attgtgattg ggaattccgc ttaccaacat
    17341 cgaggacttg gaaaaaagat tctaagtgct ttgattgaat tggctcgagt aaaaggatgg
    17401 aaagaattga gagtcaagaa aatctacacc tacaatcatg cttctaggag gtgtttcaag
    17461 tcgcttggat ttgtggaaaa tggagcaaca gaaaaaggaa tgagttttat attggaatta
    17521 gtctaatcct gccactttct cccccttaac ctttgactat tccgcaaaat tatcgtaaaa
    17581 taaagagtga atgataaaat gaggtcagag tctgttcgct ctggcgatag tagtataaat
    17641 gaggagaaac gctttgaaat tagaagtatt tgctgggcaa gaaaaaagtg aactatctat
    17701 gattgaggta gcgcgtgcta tcttggaact tcgtggtcgc gatcatgaga tgcattttag
    17761 cgatcttgta aacgaaattc aaaactacct tggaacatca aacagcgata tccgcgaagc
    17821 tttgcctttg ttctacacag agttgaactt tgacggtagc ttcatctcac ttggggacaa
    17881 caaatggggt cttcgttcat ggtatggtgt ggacgaaatc gacgaagaaa tcatcgctct
    17941 tgaagaaaat gacgacgatg aagtaacacc aaaagctaag aaaaaacgtg tcaatgcctt
    18001 tatggatggt gattcagatg ccattgacta caatgcagat gatccagaag acgaagatgc
    18061 atacgaagca gatccagctc tttcatacga tgatgaaaat ccagatgatg aaaaaaatga
    18121 agtggaagct tatgatgcag aaatcaacga aatcgctcca gatgacttgg gagaagatgt
    18181 ggatctcaac gaagacgacg acgagttttc agacgacgac gctgaaacca gcgaggaata
    18241 agagttagct attgacaatt atcctatttt taggtatcat attgtttggg cacctctttt
    18301 agaggtcggg gctccctagt tcttagggag ctatttttgt tttttcaaga agttatcttc
    18361 ttgtatttta tactcaatga aaatcaaaga gcaagctagg aaactagccg taggctgctc
    18421 aaaacactgt tttgaggttg tagataagac tgacaaagtc aggaacacat atctacggca
    18481 aggcgacgtt gacgcggttt gaagagattt tcgaagagta ttagttgtga atctggtgca
    18541 gtcgtcccag attattctta ttagtagggt cttgttttct atatcccctc gtagttaaca
    18601 agaccttgag cattttagaa agaggaatct atgtctacga aatatatttt tgtaactggt
    18661 ggtgtggtat cgtccattgg gaaagggatt gtggcagcga gtctaggccg tctcttgaaa
    18721 aatcgtggtc tcaaagtaac cattcaaaag tttgaccctt atatcaatat tgatccggga
    18781 accatgagtc cttaccagca cggggaagtt tttgtgacag atgacggagc tgagacagat
    18841 ttggacttgg gtcactatga acgtttcatc gatatcaatc tcaacaaata ttccaacgtg
    18901 acaactggga aaatttacag tgaagttctt cgtaaagaac gccgtggaga ataccttggg
    18961 gcaactgttc aagtcattcc tcatatcaca gatgctttga aagaaaaaat caagcgtgcc
    19021 gctctaacga ccgactctga tgtcattatc acagaggttg gtggaacagt aggagatatc
    19081 gagtccttgc cattcctaga ggctcttcgt cagatgaagg cagatgtggg tgcggataat
    19141 gtcatgtata tccatacaac cttgcttcct tacctcaagg ctgctggtga aatgaaaacc
    19201 aaaccaaccc aacactctgt caaagaattg cgtggcttgg gaatccaacc aaatatgttg
    19261 gttattcgta cagaagagcc agctggtcaa ggaattaaaa ataaactggc ccagttctgt
    19321 gatgtggcac cagaagccgt tatcgaatcg ttggatgttg aacaccttta ccaaattcca
    19381 ctgaacttgc aggcacaagg gatggaccaa attgtttgtg atcatttgaa attagacgca
    19441 ccagcagcgg atatgacaga atggtcagcc atggtggaca aggtcatgaa cctcaagaaa
    19501 caagttaaga tttcccttgt tggtaagtat gtggagttgc aagatgccta tatctcagtg
    19561 gtcgaagcct tgaaacactc tggctatgtc aatgatgtag aagtcaaaat caattgggtc
    19621 aatgccaatg atgtgacagc agagaatgta gcagaactct tgtctgatgc ggacgggatc
    19681 atcgtaccag gtggttttgg tcaacgtggt acagaaggga aaatccaagc catccgctat
    19741 gcgcgtgaaa atgatgttcc aatgttggga gtctgcttgg gaatgcagtt gacatgtatc
    19801 gagtttgctc gtcacgtttt aggtcttgaa ggtgccaatt ctgcagagct tgcaccagaa
    19861 acaaaatacc ctatcattga tatcatgcgt gatcagattg atattgagga tatgggtgga
    19921 acccttcgtt tgggacttta tccgtctaag ttgaaacgtg gctctaaggc tgctgctgct
    19981 tatcacaatc aagaagtggt gcaacgccgt caccgtcacc gttatgagtt taataatgcc
    20041 ttccgtgagc agtttgaggc agcaggtttt gtcttttcag gagtttctcc agacaatcgt
    20101 ttggtagaaa tcgtggaaat tcctgaaaat aaattctttg tagcttgtca gtatcaccct
    20161 gaactgtcaa gccgtccaaa ccgaccagaa gaactctaca ctgcctttgt tactgcagcg
    20221 gttgagaaca gcaattagca aaatcagaac ctttgagaaa aatctcagag gttttttgca
    20281 tacgatgata ttgcagtata tctgaggtag gggtcctctg tatgtacctg ctaccgttga
    20341 aatcaatagc gactccctct tgccctgtgc tagtgaatgg atttatcagt atattgaaat
    20401 gaaataaaat ttgaacaaat taattcggaa agccaaatca atttctagca aagttttagg
    20461 aactggattg tatagtgaat tgaaataaga tgtgaacatc tctatcagaa aagtcaaatt
    20521 aatttataga aatattttag cagtcaagat gtactgttat agattcaata cattatactt
    20581 ttttaattta atcca
//
LOCUS       DBERDS010000033        20525 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.033, whole genome shotgun sequence.
ACCESSION   DBERDS010000033 DBERDS010000000
VERSION     DBERDS010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.033"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(19..192)
                     /locus_tag="ACL73E_001394"
     CDS             complement(19..192)
                     /locus_tag="ACL73E_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGS0801354.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(351..1958)
                     /locus_tag="ACL73E_001395"
     CDS             complement(351..1958)
                     /locus_tag="ACL73E_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGS0801355.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENSNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2112..3596
                     /locus_tag="ACL73E_001396"
     CDS             2112..3596
                     /locus_tag="ACL73E_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGS0801356.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3691..4173
                     /locus_tag="ACL73E_001397"
     CDS             3691..4173
                     /locus_tag="ACL73E_001397"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGS0801357.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(4469..6574)
                     /locus_tag="ACL73E_001398"
     CDS             complement(4469..6574)
                     /locus_tag="ACL73E_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS0801358.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(7183..8163)
                     /gene="mraY"
                     /locus_tag="ACL73E_001399"
     CDS             complement(7183..8163)
                     /gene="mraY"
                     /locus_tag="ACL73E_001399"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGS0801359.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(8165..10417)
                     /gene="pbp2X"
                     /locus_tag="ACL73E_001400"
                     /gene_synonym="pbpX"
     CDS             complement(8165..10417)
                     /gene="pbp2X"
                     /locus_tag="ACL73E_001400"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGS0801360.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(10421..10738)
                     /gene="ftsL"
                     /locus_tag="ACL73E_001401"
     CDS             complement(10421..10738)
                     /gene="ftsL"
                     /locus_tag="ACL73E_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGS0801361.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(10750..11700)
                     /gene="rsmH"
                     /locus_tag="ACL73E_001402"
     CDS             complement(10750..11700)
                     /gene="rsmH"
                     /locus_tag="ACL73E_001402"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGS0801362.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            11866..12060
                     /locus_tag="ACL73E_001403"
     CDS             11866..12060
                     /locus_tag="ACL73E_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0801363.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            12076..12618
                     /locus_tag="ACL73E_001404"
     CDS             12076..12618
                     /locus_tag="ACL73E_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HGS0801364.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            12629..12871
                     /locus_tag="ACL73E_001405"
     CDS             12629..12871
                     /locus_tag="ACL73E_001405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801365.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            12882..13217
                     /locus_tag="ACL73E_001406"
     CDS             12882..13217
                     /locus_tag="ACL73E_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801366.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(13327..14328)
                     /locus_tag="ACL73E_001407"
     CDS             complement(13327..14328)
                     /locus_tag="ACL73E_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0801367.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(14388..16289)
                     /locus_tag="ACL73E_001408"
     CDS             complement(14388..16289)
                     /locus_tag="ACL73E_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGS0801368.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(16311..16604)
                     /gene="yajC"
                     /locus_tag="ACL73E_001409"
     CDS             complement(16311..16604)
                     /gene="yajC"
                     /locus_tag="ACL73E_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGS0801369.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(16604..17422)
                     /locus_tag="ACL73E_001410"
     CDS             complement(16604..17422)
                     /locus_tag="ACL73E_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGS0801370.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            complement(17409..18188)
                     /locus_tag="ACL73E_001411"
     CDS             complement(17409..18188)
                     /locus_tag="ACL73E_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGS0801371.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            complement(18203..18694)
                     /locus_tag="ACL73E_001412"
     CDS             complement(18203..18694)
                     /locus_tag="ACL73E_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0801372.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(18705..19895)
                     /locus_tag="ACL73E_001413"
     CDS             complement(18705..19895)
                     /locus_tag="ACL73E_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGS0801373.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(19907..20335)
                     /locus_tag="ACL73E_001414"
     CDS             complement(19907..20335)
                     /locus_tag="ACL73E_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIA"
                     /protein_id="HGS0801374.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
BASE COUNT         6002 a         4644 c         3664 g         6215 t
ORIGIN      
        1 ttttgtcctg ctcttgtttc aattgactat attatcagcg taatagtcta atagatagtt
       61 aaatgtagtt ggatttccac taaaggttga tgagtaagtt tttgtatctg agcctgattg
      121 gccgcaagca gctaaaagca aagcagatgc aaaagtcagg cctgcactaa gaacacgctt
      181 ctttatgttc atcttctttc tccttaatag tgggaatttg taaagttaat tgaatttcga
      241 aaatgaaagt ttataaacct tggttataaa aaacaaagga tttctgcttt ttatacagtc
      301 ctcccttgtt tttatatgat ttcaatttta aatttttctg caaaaaatat ttatagtaat
      361 tccacacaga aagcatccca tggaactaag atttgttttt caaaaacttc ttgagctagg
      421 gtgttttcaa tcaagacaga tttgactttt ccttctactg tcaagtcttg ctcttcattg
      481 gacaagttag ccacaactag gaagcgacgg tcgccatcct tacgtatata agcaaagacc
      541 ttatcagccg tatcaagcaa ttcaaagtca gctcgaatta gccagctatt ctccttgcga
      601 atttggacca gtttctgata ggtatagaaa atagaatctg gatttgccag cgcttcttgg
      661 acgttgatca tctcgtaatt tggattaact gccaaccaag gttgacctgt tgagaaacca
      721 gcgtttttgc tctcgtccca ttgcataggg gtacgggcat tgtcacgtcc aataacacgg
      781 atactgtcca tgatttcttg catcggaaca cctttttcaa gagcctcacg cgcatagttg
      841 agagattcaa tatcttctac ttgatctagt gtttcaaacg gatagttggt catcccaatc
      901 tcctcacctt ggtagatata aggagttcct ctcatgagat gaagtaagat tgcaaaggct
      961 ttggcagatt tttcgcggta ttcttggtca tttccccaga ttgagacaat acgagggagg
     1021 tcatggttgt tccagaagag ggaattccag ccgtcctcaa ctcctaactc tgtctgccat
     1081 ttgttgaaga tttcttttaa cttagcgata ttcagttctt tttgatagtg ccatttaggc
     1141 tgaccttcct gatactgaag accgatatgt tcaaactgga agaccataga caattcttgc
     1201 ccctttggat cagagtagag cttggcaatc tctggcgttg ctccccaagt ctcccctact
     1261 gtcaagagat ccttatctcc aaaggtcgcc tgattcattt ccttgagata gggatggagc
     1321 ataggaccat tattgactac cttctcgtca ggaattttgc caatcatgtc aataacatcc
     1381 atacggaaac caccaatacc tttatcaatc cagaagttca tcatctcata aattttctgg
     1441 cgaagttttt cattttccca gttgagatcc ggctgtttct tgctgaaaaa gtggagatag
     1501 tattgaccag atttttcatc gtattcccaa gcagatccac taaaaataga atctaaatcg
     1561 ttaggctcat cccgccagat atagtaatct cgctcagggc tattagaatt ttcacaggcc
     1621 tctacaaacc aggcatgctc atccgaggta tgattgacca ccaagtccat gatgatacga
     1681 atgtcacgct tcttagcttc cgcaatcagt tgatccatat cctccatggt tccaaaaatc
     1741 gttgcaatcg cttgataatc agcaatatcg tagccattat catccatagg gctgtcataa
     1801 acgggagaaa gccaaatcgc tgtgattcct aacttagcta gatagtccaa cttactggta
     1861 atacctggca aatcaccaac tccatctcca ttactatcca taaaactctt tggatagact
     1921 tgatagacta cggcattatg ccaccatttt tcttgcatct gtttacctca ttattttcat
     1981 aatctatagt atatgataac actttttaaa attttgtgca agcgtttgct taatcttttt
     2041 aatttctttt ttagctccgt agtttcctaa cttccaattt tttattatat atagaggtca
     2101 gaggtaaaaa aatgaaaaaa caagctttta gttctgaaca atatttgaat ttacaacgcg
     2161 accatatttt ggaacgcatt aaccaatttg acggcaagct ctacttagag tttggcggta
     2221 aaatgttaga agatttccac gctgctcgtg tccttcctgg ttatgaacct gacaacaaaa
     2281 tcaagctctt gcaagaattg aaagagcagg ttgaggttgt gattgccatt aatgctagca
     2341 acattgaaca ttccaaagca cgtggcgact taggcatttc ttatgaccaa gaagttcttc
     2401 gtttgattga caaattcaat gaattaggga tttttgttgg ttccgttgtc attacacaat
     2461 acgctggcca acccgctgca gatgccttcc gcaatcaact tgagaaaaac ggaattgatt
     2521 cttatcttca ttatccaatc aaaggatatc cgacggatat ggatcacatc atttccccag
     2581 aaggcatggg caaaaacgac tacatcaaaa ccagtcgcaa cttgattgtc gtaaccgctc
     2641 ctggacccgg ttctggaaaa ttggcaacgt gtatgtccaa tatgtaccac gaccaaatca
     2701 atggcatcaa atctggctac gctaaatttg aaaccttccc tgtttggaat cttccccttc
     2761 atcatccagt taacttggct tatgaagctg ccacagctga ccttgatgat gtcaacatga
     2821 ttgacccctt ccatcttcaa acctatggag aaaccactgt caactacaac cgtgatatag
     2881 aaatcttccc agtgctcaag cgcatgttgg aacgtattct cggaaaatca ccatacgctt
     2941 caccgacaga tatgggtgtc aacatggttg gtttcgctat tacagatgac gaggctgctg
     3001 tcgaagcttc taaacaagaa atcatccgcc gttactatca aacagttctt gacttcaaag
     3061 ctgaaaaagt tggcgaagct gccgtcaaga aaattgagtt actcatgaac gacctcggta
     3121 tcacacctgc agaccgtaag gttgctgtcg ttgcgcgcca aaaagcagaa gaaactggtg
     3181 gaccagccct agcctttgaa ttgccaaatg gggaaatcat cactggtaag aactcagaac
     3241 tctttggccc tacagccgct gccttgatca atgccatcaa aaaatcagct gacatcgcta
     3301 aagaagtaaa actaatcgag cctgaagttg ttaagccaat ccaaggtctt aaaatcgatc
     3361 atctcggtag ccgcaatcca cgccttcatt caaatgaaat cctgattgca cttgctatca
     3421 cagctacaga aaatcctgat gctgcccgcg ctatggaaga actcggcaac ctcaaaggaa
     3481 gcgaagccca ctcaaccatc atcttgactg atgaagacaa gaatgtcctt cgtaaactgg
     3541 gtatcaacgt aacctttgac ccatactacc aatacgaccg cttatatcgt aagtaaagat
     3601 ttcaacctct ctagcctcgg agaggttttc tctctgtctc aggaacaacc tttatgatat
     3661 aatgagagaa gaaaactgaa aggatttacc atgtcaaaag aagttattgt cgaaagtttt
     3721 gaacttgacc acaccattgt caaagcaccc tatgttcgct tgattgggga agaaacagga
     3781 ccaaaaggag acatcatctc caattatgat attcgcttgg tgcaaccaaa cgaagactct
     3841 atccctactg ccggccttca cactatcgag cacctcttag ccaaactcat ccgtacccgc
     3901 attgacggca tgattgactg ttcaccattt ggttgccgca caggcttcca catgattatg
     3961 tggggacgtc acaccagtgc taaaatcgca gctgttatca aggattcgct caaggaaatc
     4021 gctgaaacta ctacttggga agatgtccca gggacaacca tcgaatcttg cggaaactac
     4081 aaggaccaca gcctcttctc tgctaaagaa tgggcaaaac tcatcttgga acaagggatt
     4141 tcagatgatg cctttgaacg tcatgtgatt taaaatcgag taggggataa tctctagccc
     4201 ctctcacacc accgtacgta ccgttcggca tacggcggtt caactaactt ttaacgcatg
     4261 tcgttcaagg taataatcca aacacgaaac cagtccacgt ttttcaagga ctggttttga
     4321 tatagcacgt ttaagtaccg acttctgagc tactatagta tattgaaact ggaataatac
     4381 acttctacta tacgacatgc ctgtcgtacc taaaaaggaa ccagtttttt tcagctggct
     4441 ccttcttttt tatcctcaaa attctatctt aggctttctc acgaataacc aaaacgccat
     4501 cttccatatc tgcttccaga tgtttagcat ctaaatgatc caagtggaag tctgtcacct
     4561 tatcacgaat ttcttgttca accacgcgac ggagaggacg aacccccatg acttcgtcgt
     4621 aaccttcttc tgtgatataa tctttagccg cttgactaac taccaagtca atgtctttct
     4681 tagccaaggt ttggttaact tcagccaaca tcaaatctac aatcttagaa aggtcttcct
     4741 tagtcaagtg tgagaactcg atgactgcat taaagcggtt gaggaattct ggacggaaga
     4801 agggtttcaa acggtccatc aattctggtt tatccgcatc ttctgtcaag ttggcttcat
     4861 agccaaatcc agcatttgag gtcgcaataa cgacagtatt cttgaagttt actgtatttc
     4921 cttgaccatc tgtcaaacga ccatcatcta gaacttggag gagaagggta ataacttgag
     4981 gatcagcctt ttcaatttca tccaagagaa tgatagagta tggattgcga cgaacacgtt
     5041 ctgttaaggt attgctattg tcatcataac ccacatagcc tgctgttgta ccaattagct
     5101 tagaaacagc tgtgcggtca ctgtattcag acatatccaa acggataatc gcatcctggg
     5161 ttccaaacat atcgagtgcc aattgcttag caagctccgt cttaccaacc ccagtagacc
     5221 ctacaaagag gaagctgccg attgggcgat ttccttcatc aaaaccagca cggttacgac
     5281 ggatagcacg agctacaact tctacggcct tatcttgacc aatcaccttt tcttgcaagc
     5341 gatgagccat atctttcaaa cgttcgatat ctgaagctcc catttgcgat actgggatac
     5401 ctgtcattcg ttccacagat tcagccacat cgttgacact tgcagtcact ttcatatctt
     5461 ctgtgtggtt ttcgattttc ctttccaatt ctgcaatgcg tgttttatag tttagagctg
     5521 cttcaaaatc ttctgcttca actgcttttt cttgcttgtc tttttccgtt tcgatttctc
     5581 gttcaacagc atgcacatct gttactggat gttgagccgc caagtgagca gccgttacat
     5641 cgacaaggtc aatagcctta tctggcaagc tacgttgagg aatgtattga acagaataat
     5701 ccaccgctgc tttcaagact tcgtctggca agatgacatt gtggtgttgt tgatagaggt
     5761 cacgaatgcc ttgaagaatt ttaaaagtat tctctgctga aggagcattg accttcactt
     5821 cgttgaaacg acgagcaaga gcagcattct tcaagatggt gttacggtat tcgtcttgag
     5881 ttgttgcccc aatcactgtc aattctccac gagagagagc tggcttgaga atatccgcaa
     5941 gtcctttaga accactgtct ccaccagtgc taccagcacc aagaatttgg tgaatttcat
     6001 caaagaagag gataatattc cctgcttctt tcacttcatt gactaagttt tggacatttt
     6061 cttcaaagct accacggtat tgagtaccag cctcaagacc tgagatatca atagaaataa
     6121 tttccttgtt cttgatagca gcaggaacat ctccgttcac aatggcttgc gctagacctt
     6181 cgacaactgc tgtcttacca acacctgcat ctccgaccaa aacaggattg ttcttggtgc
     6241 ggcgtgagag gatttcagat gtttcttgaa tttccttgtt tcgtccgata acaggatcca
     6301 acttgccctc acgcgcttct gctgttaagt ttcgacctag ttttgcaagg acaccgtctt
     6361 gtttcatacc tgatgcctgt tgtggcattt gcacatcagt ttctgcattt cctggtaatt
     6421 gaccagtcgc acgatagtga gcaaattcct caggtgtgac ttcgcgtcca ttaattaagt
     6481 aacggcgatt ttcagaacta tatcctcgca taccacccat caattggtta aataaatcat
     6541 ccatgttatt aaaattatta aagttgttat tcatattctt tacctctttt tgtttactta
     6601 gttatgatta ctgatattga ctatctttga ccattgtttt aaaaaattta gactagctag
     6661 atcgctaccc tacgtactat ttctggtttt tctttttcaa gcaggagtag actatcttta
     6721 cctctgaaga ttgctagatg aaacatagac tcacctcttt ctattttact ttaaataagt
     6781 gttctagtaa ggctttcatt taccttacgt tcataatata ctacattggt cagaaaaggt
     6841 caagagtttt gactttaact gaccaatatt tttttacact cttcgaaaac ctcttcaaac
     6901 cacatcagct tcgccttgtc tacaacctca aaacagtgtt ttgagctgac ttcgtcagtt
     6961 ctatcaacca tctcaaaact gtatagtaaa atgaaataag aacaggataa atcgttcagg
     7021 acagtcaaat cgatttctaa aaatgtttta gaagtagagg tgtactattc tagtttcaat
     7081 ctactatatt ttgagcagcc taaagttagc tttctagttt gttctttgat tttcattgtg
     7141 tatttaaaca caaaaacacc ctgaaacatc agggtgccat tcttacatca aatacaaaat
     7201 tgcaagggtc aggagacttg ctagaagccc aactccccaa aagaagaagt caaccttcca
     7261 ctcgctccaa ggatttcctt taccagacaa tcccccaagc tcaaaatggt gatgtacagg
     7321 cgtcatacgg aaaatacgtt taccacctgt cagtttgaaa taactgactt gcatcataac
     7381 agaagttgtt tcaaaaacat atacaattcc gataatcaag agagtccatt cttggtggag
     7441 agccatagag atagctgcca gcatcccacc tagggccaaa cttcccacat cacccataaa
     7501 gaccttagca ggcttatggt taaagatgaa aaaactgagc aaaccaccaa tcatggcaag
     7561 aatcactaga agaatatcca tctgaccttg cacataggca ataactccat aggcagacaa
     7621 actaatcaca acggaaatac tagctaaacc gtcaacaccg tctgtcaagt ttactgcgtt
     7681 tgaaaaaccg actagccaga aaagagcgaa gacaatatag aaaatcccta gatgcacttg
     7741 ataaccaaag acagaaagca tatcgccacc gcgctcatag aaaagataga agataactcc
     7801 acctagaagc tgaagagcta atttttgctt aggattaagc ccctcattga ttttacgaaa
     7861 gaccttgaga aagtcatcta aaaatccgac caagccatac aagaccaaga tgaacaaaat
     7921 cattcccata ttattgctga attggctact aaatagggcg aaaaagaaag caaccaaaac
     7981 agaagtaatc aagaaaacca aacctcccat tgtaggagtc ccagcttttg cctgatgctg
     8041 tttgacatcc tcatgcatct gctggcctgt aatttgcgcc tttctataaa attggataaa
     8101 ggccggaatt cctactaaag ttagtaaaaa tgtcacaatt ccagcactga tggaaataaa
     8161 catattagtc tcctaaagtt aatgtaattt ttttaatgtc cttgatagct gtgttagcac
     8221 gaacatcttg cttctgcaca gtagagcccg aaccttgaaa ttcaagttct atattgagcc
     8281 acttagcaag ggtctcagca gtctcctttg tccaaccata catatctgga acttcctcta
     8341 ctttatcaga taagataagg acttgctgat tcggggcaag attcttccct tcttcagcag
     8401 aactgttttt aatcttcgtt cctgttccca caacgatggg ttgtacaaga ttgcgacgca
     8461 attcttctgc taaatcacca ggtgaaatat ccttgacact aggcatagga taaggacttt
     8521 gttgacttac ttgctccaaa gctttagctg ttgtttgaag attgagagag tctttcatag
     8581 ctgaagcccg ctccaagata ggattggcaa attctcccaa ctgaatacct gaataatgtt
     8641 caggttgttg gaccgtcaca tacaagataa aatcaggatt ttcagccgga ctcatcgata
     8701 cagccgagaa aatatagtcg gttaacccga ctagataacc accatttttc tcgtcagcaa
     8761 tctgagccgt accagacttg agggctacat tttgcccagg aacagttaca gttggcttgc
     8821 ctgtgctgtg gttatacatg gttccataaa ccggatccgt ccctaccaaa accatgttag
     8881 tccgagttag actagctgca tctttagaaa caggatttcc cacaatttct ttttgagatt
     8941 tccgagcagt ttgatcattt ggatcataaa cggcactaat aaatttaggc tccagcatga
     9001 caccgtcatt agcaatagct gtaaaggcac gaatcatttg cgtctgggtc actgaaatcc
     9061 cttgtccaaa tgagctttgc gcaatgttga caatattatc cgcaggaagc tgaccagcat
     9121 actcatccgt caaaccgaaa cgggtcggaa ctccaaactt aaaacgatta agataatcaa
     9181 gccaggtagc atctcccatc ttttgctcaa ggagggtcat cccaacgtta cttgagtgtg
     9241 caaaaccttg agaaaaagtc atcattctgc caccagtcaa tccttcatta acgtcccaat
     9301 ctcgaatcgt ggcatctgca atttttaact cactactatt aaagacttct cctcctggaa
     9361 aggtattatt atcaatagca gcagccaaca tcatcacttt catagtggaa cctggctcat
     9421 agttactttg gtaaaggata tcacgccaaa caaagtcctc tgtaatgcct tcttttgtat
     9481 ctgcatcaaa ggtcggtcgt tgcgttgttg ccagaatttc ccctgtttta gcactgacca
     9541 aagtcgctgt catgtacttt ccttttacct tctcttgaaa agaatccatc tgggtttcca
     9601 taaaggactg gagggggctg gaaatggttg tataaacatc cttaccgtcc atcgttcgtt
     9661 gggaaacttg ttctgttccg ggtacaatat tacccagacg atccttttca taggtaataa
     9721 tgccgtctgt ccctgcaaga atactgttca aggaactctc cattccagag gttcccagca
     9781 agctcttgct tccatcttca ttttcatgga gctgagctag gccgataaaa ctagaagcaa
     9841 attgtccgtt tgggtaacta cgattgggac tggttgtaaa atcaatcccc ttgacctctg
     9901 cagcttccaa ttcttttttg atagacatca tattggcata ggtaatccca tttccctttg
     9961 ctccaaagga aacttgcttg agattaggtt gcgagagttg ctctcttaca taggattctt
    10021 ccatgtccag atacttatga aagacctctg caaccttgtt aaattgtgtt ttttctacgt
    10081 aaagaatctt acccgttgct gacttatagt tctcatcaat gaccgcatag acattatagg
    10141 aggttgcatc ctcagcaatc gggactccat ttcggtcata aatagtccca cgtttggcag
    10201 gaactgtacg ggtggtttga tgaaccttct tagcttcctt cgctaaatct gttccaaagc
    10261 gagtgcctgt cccaataatg accgcaaaat tgactaaaaa aatggcaaaa acaaagacag
    10321 ataataaact cagacttttt ccaactctgc gtctgttttc agccggcgat ttccgatttt
    10381 tggtcgcata acggattact ctttttgtcc acttcatatc ttactccgct attctaatat
    10441 tttcattgtt taattgcaaa tcgtgtgaat tggcaatttc tttcaaacgt tctgcacgta
    10501 atagttcatt gacctcttgc ttggcatcgt ccaattcggt cttcttttcc tctatctgcg
    10561 cattgatttt tgtcaaatca ttctgcactt gcaagagctt ggtctgcata aaaataatac
    10621 taatggctac aataagagtg gttacagcaa tggaaaagta aaaagctttt tccacacgcg
    10681 aaaaccgttt aagttgcatc tgtagtattt gacctgtttt ttccattttt tctgccatct
    10741 ttttccctct tacttgtgaa tttttctggc cacgcgcaac ttggctgagt gcgagcggtt
    10801 attggcttct aactcttccg cacttggcaa gattggctta cgggacacca attccatctt
    10861 gggcttgaga tcatctggga tgaaaggcaa gccttttgga acttcaactg ttgaagcttc
    10921 cttgaacaat tgcttggtca agcggtcttc taaggaatga aaggtaatca ctgaaattct
    10981 accatccaga gccaacatat ccatagcctg ctggatggac tcatctgccg ctcccagttc
    11041 atcattgact tcaattcgaa tagcctggaa aatctgctta gcaggatgac ccttcttctt
    11101 gagttccttg gcaggtttga ccaacttgat aatctctgct aactcagtcg ttgtctcaat
    11161 cggcttcact tcacgcgctt gctcaatctt acgcgcaatc tgtttagaga atttatcctc
    11221 accgtatttg aagaaaatac gaaccaaatc atgatagtca tagtgattaa ccacttcata
    11281 ggctgtcaga ctagcatcct gattcatccg catgtccagt ggcgcatcct ttttataaga
    11341 aaaaccacgc tcacgctggt ccaattgagg actagacact cccaagtcat aacaaattcc
    11401 atcaatttcc tgaacaccag cttcgcgcaa acgtgcctgt aaatgacgga agttatcctt
    11461 gataaaggtc accattccct tctcaatgta aggtgccaag cgtttttgcg cattgtcaat
    11521 ggcattctga tcctggtcaa aggcatagag atggcctttt tcacttaatt tacttaataa
    11581 atactcgcta tggcctgctc cacccaaagt cgcatcaacg tagataccgt caggttttac
    11641 gtcaagcata tcaatcgttt cgtggagtaa gaccgttaca tgatgaaatt cttttgtcat
    11701 atcttatcta ttttaccaca aatccgacca gcttgcactt gtcagacaaa taggacaagg
    11761 agactactat ttcttcaaaa aatatgtcaa atatacttga cactttatgt ttaaaagact
    11821 ataatatagt caaatatata cgacataaat cagaaaggag accagatgaa tcgtgtgaaa
    11881 gaatttcgca aggaattggg tatttcccag ctcgaactcg ccaaggatat cggtgtctcg
    11941 agacagacta tcaatatgat tgaaaacgac aagtacaatc caaccttgga actctgtctc
    12001 aatctcgccc gcagcctcca aactgacctc aacagtctct tttgggagga agatttttaa
    12061 aaaaggagca aactcatgaa aaaagaaacc ttcactgaaa aactgatcaa acgcacatac
    12121 ggtatttctg gtccccttga cgaatacaaa cggcgtgagg ccgatagtat tgggaaccaa
    12181 gtctttatcg tcctctttta tctgatgatt ttcggaaatc ttattccact ccttctagcc
    12241 tataaatacc ctcaagaagt ggctctaatc tatcctcctc tgattttagt gattgccctc
    12301 atcgctgctg gctatgtcac ctaccaaatg aaaaaaacag gcatcacagt cattgaacca
    12361 gatatgctga atgagaaaga aagcaagcaa ctacactacc caggtctgaa agcaggtttg
    12421 ttctttggtc tatggatgtt ttttataact cctcttctca gtatactcat agatgaaggt
    12481 caggactatt ttcattctct tctcactata agaaatggtg tatcaagtat tctcggttct
    12541 attttcttcg gagcgagcat acagttcctc atctcccgtc gcattgcaaa aactaagaaa
    12601 aatcaagatg aggattagga ggaaactcat gaaaaaagaa aagaaacagt tacgttatcc
    12661 tggtcttaaa gcaggttcga tttatggaac agtgatattt tttataattc cactcattga
    12721 taccctaaca agtgaaaatc caaattttat cagttctctt ctaaatacaa aacatatttt
    12781 taaaactata ctgggagctt tctttttcgg agtgatgata catattgtcg actcacttcg
    12841 tattgcaaga gctaaaaaag accaggatta ggaggtgcct tatgaaatca ctagctagac
    12901 tactgaacat tcatgttttt atcagtattt tccttttctt cgcccttatt tcaggagctg
    12961 tttctcatac agttttacta ctcctactcc tctttcttcc tgcgctcaat aaaggacttg
    13021 agaaaataca atcaaaacgg atacctgtcc tcaacgcagc cctcttcttt ctcctcatat
    13081 cctttccaca acttttaacc aaccctgtcc aatggaaatt ttcaatattc ctagtcgtaa
    13141 ccatcatttc aagtttggcc tacttctata acttttatca agtagttaaa gaagtagatc
    13201 aaaaacagtt gatttaggag cttgctccca taatttctca tttcataagc aaataatccc
    13261 acctagcttg ttctaggtgg gattatttta tttcttaaca gagattgcaa gtcattttcc
    13321 ttcattttag aaagtcgact ctttccaatt cacactacaa tccaagactt gttgcctttc
    13381 ttcttgatta cggccttcaa tctgatcaat caaaatcttt gtagcctgtt gtccttcctc
    13441 aaaggagggc tgaaccagcg tcgaaacact tggagaagaa aagcaagtcc actccgtatt
    13501 gtcaaaacca atcaacccaa cttgtggcaa gttataattc aactctttga taacggtaaa
    13561 gactagaggt agggcccaac agttagggat aaataccaga gttttttcat cgggatcgat
    13621 ttctttttgt aaaaattcct taatttgttc caaattcgta tgcttatctt caatggttag
    13681 actggcgtga cgcatattag catctgttaa agcatccaca aaaccacttg cccgctcaat
    13741 ccgagtactc aaacgactcg tatccgctgt aatcaagaga aaatgctcat aacctttttc
    13801 gatacaggac tgggtcatgt cataaacggc atcatagtta ttggttttaa cccagctagt
    13861 ccggtgttca tagagctgac tatcaaaaaa gaccattttc ttctttttct catcgatgat
    13921 acgagaatat tttcggaaat tagaggtcgg ctgaataata aagccgtcta ctcccaagag
    13981 aagcatgctt tcaatatacc ggtcctcact ctcttggctg taattactat ttcctatcat
    14041 tacctggtag ccattctggc tggcgatatc ctcaattccc ttaacaattt ggtttgagaa
    14101 actgttggta atatcaccga tcaaaacacc gattaatttt gttcgtttgg agtttaagct
    14161 acgcgcaaca atgctcggtt tgtaatttgt ttcatgaata actttttcaa tcttttcacg
    14221 tgtctcttgg gacatttttt catatttccc gtttaggtaa aatgacacgg ttgttttcga
    14281 ggtctgagcc atttccgcaa tgtcttttat ggtcagtttc ttctccaatc taaaacacct
    14341 cctactaata cttattataa catattcact attcaaaatg cctatttcta gcactgcaag
    14401 cgaatcattc tctcatttat tttatcatat actagacatt ttccacgcat ttttgttccg
    14461 tcaacgaggc acaatttttc acctacacaa atatcctcgc ttaataacag aatcagcttg
    14521 tctgtttcgt catttttcac ttcaaaagcc agagcatttt ccacttcacg atcatctgtc
    14581 tggtagacag aatgacggat gatttcaaaa ctctcatgcg caatgatggt ataatccagc
    14641 atctgattct caaagaattg gcgcttggtg agtttgttac ttctttcaag ctcattgtat
    14701 ttaggagaaa tgatggtatc ttccaaatca aaatcaactt cactccatag tctcaactga
    14761 ttgattttcc catcttgata ggtcacatcc ttgtcaagga taaactgagt caacgcctca
    14821 tgctgacctt gacacctgat gtcatccacc aagagccaga catcctctac caacatgagg
    14881 atttttctct tgtgaagata aggcaaatca ggttctgctg accaataagc cccttcaata
    14941 taatgcactc cctccctttc tttatggtga caaaacaggg agtgaggata gtattcatat
    15001 tcccaggatc ccgtgattct ttccggagct ttcccatcta caatgcaggt cgaatgactc
    15061 caagcactct ttaagagata acgttcatat atctcccgat aagaataacg cccagcatct
    15121 atgaaaatag gttgtccttg atactgtaag caaaaactat tctcgtcact atggctatgg
    15181 gcacttccta gcggaccatt tttgaaaaat agataacgat gttcatcctt aatgcagaca
    15241 tgtccagagt cttcaaagat catggactta ggctgccaag ctctcttttc aaattcctgc
    15301 agtcgcttga ccttttctcg ccccaggaac aagaggctaa gcaaatcgac tttaacatcc
    15361 agaccgttaa gaaggtcttc cttgttcaaa accacagcag acaggctcaa aatttctgtc
    15421 gtttctgtag aatcgctatc accaaaagcc aaagttcgtc catctaagcc tgtcatcatt
    15481 tgaatatagg tcgccatctt ttccagcaac tctcggtaac tatcttgcaa gtctggaagc
    15541 aagagacaca aatccagcaa ggctttataa acctctacat gatagagaat cgactgttca
    15601 aactggcttc catctcctaa aatctgtgtc tcaatttgct gtttcaactc ctctgaagca
    15661 aaatggtaag cttcttctag gtccatctta tctgaaaaga aataatagat agcaagcatc
    15721 ggaattgttt gtaaaatccc ccagttacta agggtgtact tggcgcgata gtagcttttc
    15781 ataaagtcaa tctgcttttc tagactgacc aaaattttct ctagttcttt ctcctctagc
    15841 atgtcaaatt tcaagaggag caagagtagt ttcaaccaag taaaggaacg aatacccgta
    15901 tccaaggttc tagtcatcaa ggattgagga gaaaattctc tcacctgctc aatccaatca
    15961 aatagaaaga acttgcactt ttgaatatag tccttatctc cttctaccac ataccctatc
    16021 ataaactgca agagatattc ttgtcgattg agcatataag cccattctgg atcatcttca
    16081 aatacttgat cccataccat cggctggatt tgatggattt ttgaacaagg ctccatatcc
    16141 caaggactat caaacataaa acgattgtcc atcaagcgtt caagggaact cttgactttc
    16201 tcatagtctt ttgaacagtg cgacaagata taatcacgac attggtttcc atcgactctt
    16261 tcaaaaaatt gtcttctttc ttctttcatt atctattacc agaaaaagaa ctacttaaaa
    16321 agcagttctt ttgtctttcc cattacactt tccttttcta catagatgac cacacctttt
    16381 gcaatctgca aggagaccaa gtcatctttg atagaaatga tttttccatg aattccagac
    16441 aataacaaca cttcatcacc agatgttaaa gaagctaaat actcttgtcg ttgctccgtc
    16501 tgtttgcgaa gcaacttttg ctgacgaata gaatgaaagc ttgacagtaa aaggggactc
    16561 actgccaaga caatcactat tccataaaac aatgttgtat ccattaagct ataatcttaa
    16621 gccagcttcc gataattccg atgacaactg ttaaaataac gagtttatat gttgtccatt
    16681 tcttttcttt gatcaagtag taaactaaaa gtgtaaatag ggctggtaga agagctggag
    16741 caaccttatc aagcattccc tgaatactta cgatactttg tttagcgtct gctttaactt
    16801 cccctgcagc aaaggtaatc ggcaccataa tcttaacaga tgtcgctgcc aaaccagcaa
    16861 ttacggttac accgataata ttggcaatac gagaaatcgt tgccatctgt tcgcttagtt
    16921 tatcaatcac agttgttcct agtttgtatc catacagacc agttgacaat ttaatcgctg
    16981 ttaaaatcgt attcatcgca aggaagaaca agattggacc gacaaccaag ccttcttgag
    17041 caaacgaagc tgcgatggtt gagaacaatg gagctaaaca gaattgagaa agagaatccc
    17101 caatacctgc caatggtccc atcaaggcca tcttgatgct acgtgtttct tttgccggac
    17161 ggccattttc caacattaca agatgcaagc tggtaataaa aggcaggaag tgtgggttgg
    17221 tattatagaa ttcacagttt tcttccaagg cttggtagaa accttcctga tcctctccat
    17281 agtgtttttt caaagcagga tacatcacat tggcatatcc caacccttga tagttactat
    17341 agttaaatcc attttgacaa aagaatgccc gcaaagacgt tttaagataa tcacgttttg
    17401 ttaatttgtt agatccagtc atcgtgtgct tcctcctcta ccacatgatt cgctgttttt
    17461 ggcttgttat aaaattcaat caaagcaaag atagtaccta caattgcaat accaattgtt
    17521 gggatgttta gataagctgc acaaacatat cccaacaaga caaagggaat caactctttc
    17581 ttagccatca ctgacaagat catcgcaaaa ccgatagctg ggagcatttt accagcaact
    17641 gtcaaacctg taagtaatac cggtggaatg tagtctacga gtttcaacaa ggtatccatt
    17701 gaaagggcac ccaagcaacc caaggtaaat ccaataaagg caaacaacca aattgttgca
    17761 tttagagtaa acttgaattt cttcaaatta tggtttttca agtgcttcat cgccgtttca
    17821 ggcgcaccag cacgtacagt gtaggcgaaa gtttgtaaga attgaatcgc cacagcaatc
    17881 ggagtagaga gggcaagagc cgcttctgga ctgactttac cagcactagt gatagccatc
    17941 aaggtaccaa agataccagg tccgattggg tttggtggaa cagtacctcc agcaccaaca
    18001 ccgaatccca tataagccaa ttcaccaata gctcccattg caagagcagt aggcagatca
    18061 cctagaataa ttccgacacc aaatgacaga acaatacatc tattggtgta aattcctaac
    18121 agcattccac taaaacagaa agctgtccat aatccaatta aaatcgcttg aaatacatta
    18181 atcgacataa cgatctcctc ttttaaatat agtccataat gttgacttga acagctccat
    18241 catttcctgt tggagttgtt ttcgtattaa atgttacttg atgagtttgg cttaattcct
    18301 tgagggctgc cttgtcctct tcacccagga agatggagcg tgtcacttgc tctttaccag
    18361 gggcattgtg aatgttccca atattgattt ctttgatagg gacaccacct tctaccaagg
    18421 ttaaagcgtc ctttacatcc tttacaacga taaagatcgt ttgagcagga ttagccttgt
    18481 gaatgatatc aatcaccttt tgcaaaggga agaaacgcat ggcaactgag tctggcacaa
    18541 ctgttttcat cagagtttgt tgcatcttgt ccgtgcttac ttcgtcattg gcaacaatga
    18601 ccgtattaca agctaggtat tttacccaaa gttgtccttg tccatgaatc aaccgttcat
    18661 cgatacgggt cataataata tttggcattg tcatatttct cctcctacca atataggttc
    18721 cagtctttgt agaaacggat aagggcttct aggtaatagt agtcacccca gatattgcct
    18781 tcatccactc ctttacctga atgccatgag tacacaccgt ggagaagact tgtcccacca
    18841 ggggtaaatt gatcatttgc ataatgttcg atcaaggaac gaagcatggc atgcatagca
    18901 tgtttataaa tatctttgtc agcatccacc tctgggagat gttttagcat ttcatgaatc
    18961 ccacagacgg cgatagctgt tgctgaagaa tctcgtgatt gagcactacc atcattaaaa
    19021 atcaaatccc aataggacac atgatctttt ggcagacgat tcaagaaata attggtcaca
    19081 cccttaaaca agtcaaagca ggactcgtct tttaagtgac gataagtcaa aggaatacca
    19141 tagactcccc atgattgacc acgtgcccag catgaatcat cactataccc ttgtctcgtt
    19201 acacctttaa agggttgacc tgtctcagga tcaaaataga aggtgtggaa ggacgaagcg
    19261 tcatcacgga ttacattatt agctgaagca tagaaatgac tttctgcaat atcgtagtat
    19321 ttttgatcgc ctgtttcttg ataagcaaag aataagagtt ggatattgag caagcagtcg
    19381 ataatcaaac ggtaatgctc tttcttgccc aagtctcccc aagcttgaat aaaaccacct
    19441 ttttcttgat agcgttcaat caacttatct gcagctttca aggttgcttc tctagcctct
    19501 ccatctccat ttatcttata ttcagccata caagacggtg tgtacaagaa gccgagatca
    19561 tggtgatcca attctactct cttattgaca cgatccagga aagaaagaac atttttatga
    19621 gcgatgtttt taaatgcatc ctgttgactg tattcataag ccaaccacag ttctcctgtc
    19681 cagaaaccat tggtccattc cgtgttatcc atgattggat agacattatc aaaggtagct
    19741 ggcgtcggga aatcttcctt gaaatagtca aggttgagtt ctaactgccg aataacctta
    19801 tcgattgcct ggccgacttc ttctttcgtc agaagtggta cttctaagaa gcgctcaggc
    19861 gattttattt tttcaatcgt aacctttttt atcattcttt taccctttaa atacccgatt
    19921 cgaaatcttc ttcctctgca tccgttgaaa acaattcttt accatttacg actccgccct
    19981 gggccgccac tactgattta ttaacaacct catcaaagct atgagccatt ctagcaaaga
    20041 ctgcttccat taacatggct aagttcaaac ccgagagaac attcattgtt ttgactggat
    20101 tttctcccat tatggtagaa gaaaccttga atggcgatcc tcccaagaga tcacttagga
    20161 ttaaaacttc ttcttcattt gaaattgcaa gtaagatttt ttgcttgagt tcatctgctg
    20221 acattccttc cacaaagtca atcgcctcca cattttcttg attacctgca atcaattgta
    20281 aagaactata aatccctgta gcaaaatgtc catgccctac aagtacaatt ttcatctttt
    20341 ctcctttctt gtttaggttt accggtttac tttatattcc ccattgtaat cctttatttt
    20401 tatcttgtca atagtttttt taaaaaaata ttagcgcttt cattatcttt ttaaccattt
    20461 taataaacag aaatttcaaa atattccgtt tttcaggaaa acaaatcttt ttataaataa
    20521 aaata
//
LOCUS       DBERDS010000034        20278 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.034, whole genome shotgun sequence.
ACCESSION   DBERDS010000034 DBERDS010000000
VERSION     DBERDS010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.034"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            113..3214
                     /locus_tag="ACL73E_001415"
     CDS             113..3214
                     /locus_tag="ACL73E_001415"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGS0801375.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3297..4304
                     /gene="pfkA"
                     /locus_tag="ACL73E_001416"
     CDS             3297..4304
                     /gene="pfkA"
                     /locus_tag="ACL73E_001416"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGS0801376.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADSKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4363..5868
                     /gene="pyk"
                     /locus_tag="ACL73E_001417"
     CDS             4363..5868
                     /gene="pyk"
                     /locus_tag="ACL73E_001417"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGS0801377.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6046..6393)
                     /locus_tag="ACL73E_001418"
     CDS             complement(6046..6393)
                     /locus_tag="ACL73E_001418"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0801378.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDKYITIAKTFVEIHLNFLINLC
                     ISYFILNENQRAN"
     gene            complement(6725..6832)
                     /locus_tag="ACL73E_001419"
                     /pseudo
     CDS             complement(6725..6832)
                     /locus_tag="ACL73E_001419"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
     gene            7632..8504
                     /locus_tag="ACL73E_001420"
     CDS             7632..8504
                     /locus_tag="ACL73E_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGS0801379.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPTDDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8637..8994)
                     /locus_tag="ACL73E_001421"
                     /pseudo
     CDS             complement(8637..8994)
                     /locus_tag="ACL73E_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9137..9448
                     /locus_tag="ACL73E_001422"
     CDS             9137..9448
                     /locus_tag="ACL73E_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801380.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKECEELRQIITTIFEQKMNKHSI
                     K"
     gene            9452..10168
                     /locus_tag="ACL73E_001423"
     CDS             9452..10168
                     /locus_tag="ACL73E_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGS0801381.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEEFICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10297..11112)
                     /locus_tag="ACL73E_001424"
     CDS             complement(10297..11112)
                     /locus_tag="ACL73E_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGS0801382.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQVTNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11109..12014)
                     /locus_tag="ACL73E_001425"
     CDS             complement(11109..12014)
                     /locus_tag="ACL73E_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGS0801383.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSIVVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSHLSPAKKVFQVFVQAIDEFFDTGRYLVFGCLFASVIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(12015..12146)
                     /locus_tag="ACL73E_001426"
     CDS             complement(12015..12146)
                     /locus_tag="ACL73E_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGS0801384.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKAKAEKKN"
     gene            12426..14555
                     /locus_tag="ACL73E_001427"
     CDS             12426..14555
                     /locus_tag="ACL73E_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGS0801385.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGKKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            14542..14991
                     /locus_tag="ACL73E_001428"
     CDS             14542..14991
                     /locus_tag="ACL73E_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGS0801386.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            15050..15322
                     /locus_tag="ACL73E_001429"
     CDS             15050..15322
                     /locus_tag="ACL73E_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGS0801387.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGRFW"
     gene            complement(15676..15867)
                     /locus_tag="ACL73E_001430"
     CDS             complement(15676..15867)
                     /locus_tag="ACL73E_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801388.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16295..17053
                     /locus_tag="ACL73E_001431"
     CDS             16295..17053
                     /locus_tag="ACL73E_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801389.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17055..19043
                     /locus_tag="ACL73E_001432"
     CDS             17055..19043
                     /locus_tag="ACL73E_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801390.1"
                     /translation="MFRLTNKLAVLNLIKNRKLYYPFALAVLLAVTLTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVIITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDNGYKIKEKEVFRYTYFGVANQEGNKLTFFEKGQNRVQPTTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19085..19759)
                     /locus_tag="ACL73E_001433"
     CDS             complement(19085..19759)
                     /locus_tag="ACL73E_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGS0801391.1"
                     /translation="MDSNFAGRLNILRAGVLGANDGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(19701..>20278)
                     /locus_tag="ACL73E_001434"
     CDS             complement(19701..>20278)
                     /locus_tag="ACL73E_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS0801392.1"
                     /translation="GQSIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSR
                     HQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYA
                     SWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMAN
                     LNLKFSVRNKSRNRFKFCRSFKYPARRCSWC"
BASE COUNT         6197 a         3706 c         4289 g         6086 t
ORIGIN      
        1 aatacaaatg gatagaaaat aaattagtaa gctgatgaaa tttttctcaa gagaagccat
       61 ttataggtga aaatggtata atatagtgag aaggatagag gagaagtgta aattgatcgc
      121 acaactagat acaaaaacag tctatagttt tatggaaagc gtcatttcga tcgaaaagta
      181 tgtgagagca gctaaagaat acggctacac tcatttggct atgatggata ttgacaatct
      241 ttatggcgct ttcgactttc tagagattac aaaaaaatac ggcattcatc ctttgctagg
      301 gcttgaaatg acagtgtttg tagatgatca ggaagtgaat ttgcgctttt tagctctatc
      361 tagtgtgggc tatcagcagt tgatgaagct ttcgacagcc aagatgcagg gggagaaaac
      421 ttggtcagtc ctgtcccagt acctggagga tatcgcggtc attgtgcctt attttgatag
      481 agttgagtcg ttagaactag gctgtgatta ctatataggg gtttatccag aaacactagc
      541 aagcgaattt catcatccta tcttacctct ttatcgggtc aacgcttttg aaagcaggga
      601 tagagaagtt cttcaagttt taacagcgat taaagaaaat ctaccgctca gagaagttcc
      661 cttgcgttcg agacaagatg tctttatatc agcaagttct ttagagaaac tattccaaga
      721 gcgttttccg caagctttgg acaatttaga aaagcttatt tcaggcattt cttacgactt
      781 ggatactagt ctgaaactgc ctcgttttaa tccagctaga ccagcagtag aggagttgag
      841 agagcgtgct gaactggggc ttgttcagaa ggggttgact agtaaagaat atcaagatag
      901 actagaccaa gaattgtctg ttattcatga tatgggcttt gatgattatt tcttggttgt
      961 ttgggatttg ttgcgttttg gacgatcgaa tggctattat atgggaatgg gaaggggttc
     1021 tgcagtaggc agtttggttt cttatgcctt agacatcacg gggattgacc cagtagagaa
     1081 aaatctgatt tttgaacgct ttcttaatcg tgaacgctat accatgcctg atattgatat
     1141 tgatatccca gatatttatc gtccagattt tatcagatat gttggtaata aatatggtag
     1201 taaacatgcg gcacaaatcg ttactttttc aacctttgga gccaagcaag ctcttcgaga
     1261 tgtcttgaaa cgctttggtg tgccagagta tgaattatct gcaattacta agaaaatcag
     1321 ttttcgtgac aatcttaagt cggcctatga gggcaatctc cagtttcgtc agcaaatcaa
     1381 tagtaagtta gaataccaaa aagcttttga gattgcttgc aagatagagg gctatccaag
     1441 gcaaacctct gtccatgcgg ctggtgttgt aattagtgac caagatttaa ccaactacat
     1501 tcctctaaag tatggtgatg aaattccact gactcagtat gatgctcatg gagttgaggc
     1561 tagcggactt ttgaagatgg actttctggg actacgaaat ttgacctttg tccagaagat
     1621 gcaagagttg cttgctgaaa cagaaggtat tcatctgaaa attgaagaaa tcgatttaga
     1681 agacaaagaa acgttagctt tatttgcctc tggtaataca aaaggtatct ttcaatttga
     1741 gcaaccaggt gccattcgtc tgcttaagcg tgtgcaacca gtctgttttg aagatgtcgt
     1801 cgcgactact tctctaaatc gaccgggtgc tagtgactat atcaataatt ttgtggcaag
     1861 aaagcatggg caggaagaag tgactgttct ggatccagta ctggaggata ttttggctcc
     1921 aacctacggc ataatgctct atcaggagca ggttatgcag gttgcccagc gatttgctgg
     1981 atttagtctt gggaaggccg atattttgcg tcgagctatg ggtaaaaagg atgcttctgc
     2041 tatgcatgag atgagggctt cctttattca aggctccata gaagcaggcc atactgcgga
     2101 aaaagcagag caggtttttg atgttctgga gaagtttgca ggctatggtt ttaacaggtc
     2161 acacgcctac gcctactcag ccttggcctt ccagttggct tattttaaaa cacattatcc
     2221 agccatattt tatcagatta tgttgaattc tgctaacagt gattatgtaa cagatgcctt
     2281 agaagcaggt tttgaagtag ccccattgtc catcaacacg attccctatc acgataaaat
     2341 tgccaacaag gccatctatc taggtttgaa atccattaaa ggagtcagta atgatttagc
     2401 tctctggatt attgaacata gaccttattc taacattgaa gattttatag ctaaattacc
     2461 tgagaattat ctgaaacttc ctctgctaga acctttggta aaagttggtc ttttcgattc
     2521 atttgaaaaa aatcgtcaaa aagtatttaa taacttagct aatctatttg aatttgtgaa
     2581 agagttggga agtttgtttg gagatgctat ttatagttgg caggaatcgg aagattggac
     2641 ggaacaagaa aaattttata tggaacaaga gcttttaggg ataggtgtca gcaaacatcc
     2701 actacaagct attgcaagta aggctattta cccgattacc ccaatcggaa atttgtcaga
     2761 aaatagctat gctattattt tggttgaagt tcagaaaata aaagtgattc gtaccaaaaa
     2821 gggtgaaaat atggccttct tacaggcaga tgatagtaag aaaaaattgg atgtcactct
     2881 cttttcagac ttatatcgtc aggttggaca ggaaataaaa gagggagcct tctactatgt
     2941 aaaaggaaaa atacaatcac gtgatggccg tctgcaaatg attgcacaag aaataagaga
     3001 agcagttgct gaacgctttt ggatacaggt gaaaaatcat gaatcggatc aagaaatttc
     3061 acgtatttta gaacaattta aaggcccaat cccagtcatc atccggtatg aagaggaaca
     3121 gaaaaccatc gtttctcccc atcattttgt agctaaatcc aatgaattag aggagaaatt
     3181 gaatgaaatc gttatgaaaa cgatttatcg ctaaaaatac ggaaaataga agaattttaa
     3241 aatcaaatgt gatataatca agaagaatgt taaaagaaaa aggagcataa accaatatga
     3301 aacgtattgc tgttttgact agtggcggag acgcacctgg tatgaacgct gctatccgtg
     3361 cagttgttcg tcaagcaatt tcagaaggaa tggaagtgtt tggtatctat gacggatatg
     3421 ctggtatggt tgccggtgaa attcatcccc tagatgcagc ttcagtagga gacatcattt
     3481 ctcgtggtgg tacttttctt cactcagctc gttatccaga gttcgctcaa cttgaagggc
     3541 aacttaaagg gattgagcaa ttgaaaaaac acggaattga aggtgtagtt gttatcggtg
     3601 gtgacggatc ttaccacggc gctatgcgtt tgactgaaca tggcttccca gctattggtc
     3661 ttccaggtac aatcgataac gatatcgttg gtactgactt tacaatcggt tttgacacag
     3721 cggttactac tgccatggac gctattgata agattcgtga tacatcatca agtcaccgtc
     3781 gtacttttgt aatcgaagtt atgggacgta acgctggtga tatcgctctt tgggctggta
     3841 ttgcaactgg tgctgatgaa atcatcatcc ctgaagcaga ctccaagatg gaagatatcg
     3901 tagcaagcat caaagctggt tatgaatgtg gtaaaaaaca caatatcatc gtcttagctg
     3961 aaggtgtgat gtcagcggct gaatttggtc aaaaacttaa agaagctgga gatacaagcg
     4021 accttcgtgt aacagaactt ggacatattc aacgtggtgg ttctccaact gcgcgtgacc
     4081 gtgttttggc gtcacgtatg ggtgcacatg ctgttaaact tcttaaagaa ggtatcggtg
     4141 gtgttgcggt tggtattcgt aacgaaaaaa tggttgaaaa tccaattctt ggtactgcag
     4201 aagaaggggc attgtttagc cttactgcag aaggtaagat tgtggttaac aacccacaca
     4261 aagccgatat tgagctatct agcttgaata agagcttgtc ataatttaca atttagttaa
     4321 taagaccaaa aaggtcatat atataaagga gtcacaaaaa tcatgaacaa acgtgtaaaa
     4381 atcgttgcaa ctttgggtcc tgcggtagaa atccgtggtg gtaaaaaatt cggtgaggac
     4441 ggatactggg gtgaaaaact tgatgttgaa gcttcagcta aaaacattgc taaattgatt
     4501 gaagctggtg ctaacacatt ccgattcaac ttctcacacg gcgaccacca agaacaaggt
     4561 gagcgtatgg caactgttaa acttgcggaa aaaattgcag gtaaaaaagt tggtttcctt
     4621 cttgatacaa aaggacctga aatccgtaca gaattgttcg aaggtgaagc taaagaatat
     4681 tcatacaaaa ctggtgaaaa aattcgtgtt gcaactaaac aaggaatcaa atcaactcgt
     4741 gaagtgattg cgttgaacgt tgctggtgct cttgatatct atgatgatgt tgaagttggt
     4801 cgtcaagttt tggttgacga tggtaaactt ggtcttcgtg tggttgctaa agatgatgaa
     4861 actcgtgaat ttgaagttga agttgaaaac gatggtatca tcgctaaaca aaaaggtgtg
     4921 aacatcccta acactaaaat tcctttccca gctcttgctg aacgcgataa cgacgatatc
     4981 cgtttcggtc ttgaacaagg tatcaacttc atcgcaattt cattcgtacg tactgcaaaa
     5041 gatgtgaacg aagttcgtgc aatctgtgaa gaaactggaa acggacatgt tcaattgttc
     5101 gctaaaatcg aaaaccaaca aggtatcgat aacttagacg aaatcatcga agcagctgat
     5161 ggtattatga ttgctcgtgg tgatatgggt atcgaagtac cgttcgaaat ggttccagtt
     5221 tatcaaaaaa tgattatcaa gaaagtcaat gctgcaggta aagttgttat cactgcaaca
     5281 aacatgcttg aaacaatgac tgaaaaacca cgtgcaactc gttcagaagt atcagacgta
     5341 ttcaacgctg ttatcgacgg aactgacgct acaatgctgt caggcgagtc tgcaaacggt
     5401 aaatacccac tcgagtcagt aactacaatg gctacaatcg acaagaacgc tcaagctctt
     5461 cttaatgaat acggacgtct tgattcagat tcatttgagc gtaactctaa gacagaagta
     5521 atggcttctg ctgttaaaga tgctactagc tcaatggata tcaaattggt tgtaactctt
     5581 actaagacag gtcatactgc acgtttgatt tctaaatacc gtccaaatgc tgacatctta
     5641 gcattgacat ttgacgaatt gacagaacgt ggcttgatgt tgaactgggg tgttatccca
     5701 atgttgacag atgctccatc ttcaactgac gatatgttcg aaatcgctga acgtaaagcg
     5761 gtagaagcag gtctcgttga gtcaggcgat gatatcgtta tcgttgctgg tgtgccagta
     5821 ggagaagctg ttcgcacaaa cacaatgcgt atccgcacag tacgttaaga aaaatataaa
     5881 aacctatcat atccagcttt ctagtctgta tgatgggctc tttttttgtc caggggggca
     5941 aaaagggggc aaaactttca taatggattg atactcttcg aaaatcaaat tcaaaccacg
     6001 tcagcgtcgc cttaccgtac tcaagtacag cttgcggcta gcttcctagt ttgctctttg
     6061 attttcattg agtatgaaat aagatatgca caaattgatt aggaaattca aatgaatttc
     6121 tacaaatgtt ttagcaatcg taatgtactt gtctagattc gatctgatat attttcgatt
     6181 taatgatatg gtatttaaaa cctccaaagt agcttgctcc attcttttac ttacgtgagt
     6241 gtagatgtta tttactgttt tagcgttttt gtgttccact ctaaccatta tagcattctt
     6301 ctcagctagt gtactaagga gtgtgtgcct gaaaatatgg gaactaaggg gctggtttat
     6361 cggtttctct agtttagtat ttgccttttg caaagtgatg ttaaatgcct ttctctaaat
     6421 ttacatatca ctattgttta acaaaatcta atctacttta ggtcacttat tctttttttg
     6481 aaatgtagaa tgaacttttt caaagttttt cgaatctttt aaaatctgtt tgttttatat
     6541 cgccattctc cccctttttt aattctccct atatagcctg acaactttcc cgatggtacg
     6601 aatatggttg ctttcgtcta ggtggatgtc ggggtatttg ggattgagtt tttttaaggt
     6661 agccttggcg gagtttcttg acatagttag cgccgtctac ttggaagatg ccgatggtat
     6721 tatagtcaat ctgtggggta ttcttgataa ataggtagtc gctgtttctt atctttggct
     6781 ccatggactt gctgatgaca taagcgattg ggtcgtagtc gtctgggata atggaaactc
     6841 catatctaaa tcgttgtcct gcatcgagcg gctacctgca gagataaact atctaacacg
     6901 agagtaagta gtctgtctgt agtcgtccag tctgatgatt tttacgatac ttcgtttttc
     6961 tgatcataca gttgcctctc ggcataggtc agaactttac cttgtctgga tggtgcccgt
     7021 tggtcgtaga tagattggat atcgctagga gaatcctttt gaactggaga aaagagggca
     7081 tcaatcaagc tactgaatac tttaactaag tcaaatatag tatttttctt agtagaccta
     7141 accctttttt cataatttcc aatggtgttt ttacttatac caatcttagt acccaattct
     7201 tattgagttc aaccattact agtctatatt gttttatagt tgattgagtt tggaatagta
     7261 cgctgtagct gctaaaacat ttctaggaat taatttgcct ttcctaatag agttgttcat
     7321 atcttatttc aatctactat atttttcgcc tctaacaatc gcaatctctt ctttatctac
     7381 gaacgaaatc gctttctatt tttgtaagta aagcatcaca cgaaatccac gaaaatgaaa
     7441 acctttgttg tgttttcgta aaaaatttgt tgacagagca cgaaacgcct actataatta
     7501 aatcaagctt aaggaaataa caaaaaaaca aatcggaggg aaagacgatg aacacattaa
     7561 atgagaaagt aatcaatatc tgtaaagcaa tagttaaaga aactttaatc caagacattt
     7621 aggagaaaga aatgaagaaa tcaagaaaat tagccacatt aggaatctgt tcagctttgt
     7681 ttttaggctt ggctgcttgt caacaacaac atgctacttc tgaggggacg aatcaaaggc
     7741 aaagcagttc agcgaaagtt ccatggaaag cttcatacac caacctaaac aaccaggtaa
     7801 gtacagaaga ggtcaaatct ctcttatcag ctcacttgga tccaaatagt gttgatgcat
     7861 tttttaatct cgttaatgac tataatacta ttgtcggctc aactggctta tcaggagatt
     7921 tcacttcctt tactcacacc gaatacgatg ttgagaaaat cagtcatctc tggaatcaaa
     7981 agaagggcga tttcgttggg accaactgcc gtatcaatag ttattgtctt ttgaaaaatt
     8041 cagtcaccat tccaaagctt gaaaagaatg accagttgct tttcctagat aatgatgcga
     8101 ttgataaagg aaaggtcttt gattcacaag ataaggaaga gtttgatatt ctattttcga
     8161 gagttccaac tgaggcaact acagatgtca aggttcacgc tgaaaagatg gaaacattct
     8221 tctcacaatt tcaattcaat gaaaaagctc gaatgctgtc tgtagtcttg cacgacaatc
     8281 tggatggcga gtatctgttt gtaggccacg ttggggtctt agtacctact gatgacggtt
     8341 tcttatttgt agagaaattg actttcgaag agccctacca agcgattaaa tttgctagta
     8401 aggaagattg ctacaagtat ttaggcacca agtatgcgga ttatacaggc gagggactgg
     8461 ctaagccttt tatcatggat aatgataagt gggttaaact ttaatagtgt tatgatatga
     8521 cagtaatctt aggattttta tttctatttt tgatgagttg gtgggttatt tcaatcgtta
     8581 atagccagaa accacgcaaa aatgaaacat ttattggcta tatccaaaga tacgatattg
     8641 atgggaatgg ctatcaatca ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgt
     8701 aaaactactt tgaacaagag ttacttcaac ccattggatc cgacggagta agttgctttc
     8761 gtggatacca aaaacagccg caatttcttc ataagtgcgg tattctcgca catattgaag
     8821 agtggccata agaaggtctt ctaggcttaa tttaggtttt cgtccccctt ttgtgtgttt
     8881 aagttgataa gctgttttta atacagctaa tatctcttca aaagtggtgc gctgaacacc
     8941 aacaagacat ttaaatcgtg catcagttag ttgtttactt gcttcataat tcatagaact
     9001 actataccat attttgtttc gcaggaagtc taatgctaaa atcttatcag tgagaagatt
     9061 tcttaaagtt tattctttgt aatttcatct gtattagtac ataatttaac ttagagaaaa
     9121 taggaggact aatcgaatgg aattaaaaga ttttacagaa aaagaacagg aaatgattaa
     9181 gaaaaggctt acaatgtcta atattagtga caaagaaact actgagaaga ttctggcgct
     9241 agtaccacaa gacttgatta agcgaatccc gttttttgtc agaaaacatg ctacaacacg
     9301 tacgattaaa cgcatttcaa ttgaacaccc tgaactctac gctgtagctc aaacaagtgg
     9361 tgagattcca gaaaaagaat gcgaagaatt gcgtcagatt atcacaacta tctttgaaca
     9421 aaagatgaat aagcatagta ttaagtagag aatgaaaaaa tattttattg gcggtttggg
     9481 aagcaatgcc tatcatagca aggattttct tcaagaacta gattcgcagg tctattttct
     9541 aaatccatat gaaaagcatc ttcgagatga aacagaattg aaatcatggt ttaaaaatga
     9601 gattgtagag gaagaattta tctgtctgat aggtcattct cttggaggag atttagctcg
     9661 ttatctcgca tcggaatttg aagaagtaaa gaaactgatt cttttggatg gtggctatct
     9721 agatttagat aagattttac ctttggatac agagttagag gaaactaaaa attatatcaa
     9781 atctcaaatt gttttggact tagatgttct tacttctaaa gaaaaatctg aagcaaagca
     9841 ttggtcagaa aatatggaga aagctgtaag acagtcctat cactggaatg ttgagtataa
     9901 tagatatgag ttggctataa attatgaaaa tatagaagcg atactccgcc tacggagaaa
     9961 aatacaagct tttaagagag aagtgggaga taccttgttt attagtcctc gctatcctaa
    10021 tgaagctaca tggagagagg aagccctaaa agaattgcca gactattttg atactatttt
    10081 tttagaaaac tttggccatg agctttatac tcaagcacct aaagaaatcg ctagtctaat
    10141 gaatgagtgg ctcgcttatt ttctatgagc tacttgtatt gctggaaatg gtataagatg
    10201 aaaatctaca agtcactaat tttcatataa caaaaaacga acaggctctt tttctgttat
    10261 tcagaagaga acttgttcgt ttttatcttg attttcttaa aaagctctat atacataggg
    10321 attttctggt ttatcgactt tggtaaagct gtcgatttcc aaggttggaa ggttttgttt
    10381 gagttcttta tggtagtgat tgaccagttt tcctttggct gttatccaag tgttgttttc
    10441 atactgccgg gtattgccct tggtcagcaa tccatagaca ccagaatctg cgatacagtg
    10501 gataatgccg aatcggaaca gaaattgact attggcatga ctggggtcgt tatagacaaa
    10561 gcctgtaaac tggattgtct tgccctcaaa ctcatctgga tagtcgtaga tagcctccat
    10621 gacttccata tagttttcat tagtgacctg aatactatct tgggataagt atttatccgc
    10681 cgccgttcgc atttcctttt cataggctga ttttgaaaaa taagaactgg tatctggttt
    10741 caaatattgg cttgtcgtcc cttcgcttgt ctgaatggct agatccgttc cttccgatag
    10801 ggggaaatga taacctttag cagaaacagt ctgagaatcc aagctaacag ttgggaaagt
    10861 taagccgatg acaagtggaa tagccagaag agaaatactc gtcatcttgg ctaatcggct
    10921 gttcagatga ctgtgggttt tgacttgctt catccagata tacaattgaa cgatagccaa
    10981 gataaaagaa agcaccatgg agatataggc cagataggaa tagtgcatgt tgatgtactg
    11041 gtttagtttg cccgacagat ggaggtaaat agtcagttca aaatagccag ctaaaactaa
    11101 aaatcgaatc ataggatgac tccaatcaag agagaatagg ctaaaacgac cagagtcaca
    11161 atcgtaatga agtgactaat aaatcgtgct ttcaagtaat ttttcatcat aagaatattt
    11221 ttgatatcca gcattgggcc aatgacgaga aaagccagaa ctggagccaa accgaaactc
    11281 gagagtagag aagccccgat aaaggcatcc gcctcactac agagcgaaag aagaaaggcc
    11341 aaaatcatca agagcaggat ggcaaaaaga ggagtcgcac tgatagaggt cagaatccga
    11401 gtcggaacat aaacctgtat aacagaggca aagagacagc caaataccaa ataacgtccc
    11461 gtatcaaaaa actcatcaat ggcttgcaca aagacctgaa aaactttttt tgcaggactt
    11521 aagtgagaaa aatcatgctc atgacaggct agacgatttt ctttttgaat cggttcttgc
    11581 cagaaaaatc ctagaaaaat tcctagtatt acagccacaa cgatggaacc cagagctcgt
    11641 aatagggcga catggaagga gttgccaaag gcagaatagg tcgcaaaaag aacaatggga
    11701 ttgataacag gtgctgtcac aagaaaagga acggccgtgt aacttggaac ctttttttcc
    11761 agaaaacgat tgatgatggg gacgattcca cattcacagg aagggaaaag tataccgaca
    11821 aaggtcccaa aaaagattct cccccaacga tttcgaggga gaaaatgata aaccttgtca
    11881 ggtgtgatat aaacttcaat cagccctgag acaatacttc ctatcagaac gaagggaagg
    11941 gcttcaatga taatggagag aaaaatggct ccagtttgaa gtacactaga tgggagttgt
    12001 tgaaaagcag tcatctagtt tttcttttct gctttggctt ttttctcttt gtcatcaggg
    12061 aaagtgactt gtttcaaatc agggagttta gcaaactctt caaacatctt gtccaagtcg
    12121 tctcgttttg taaatttgac agccataggt gtacctcgat tctaaattct acctctatta
    12181 tactattatt ttgcggaaaa gggagttttt taatttgttt tcgatagttg atactcttcg
    12241 aaaatctctt caaaccacgt cagcttcgcc ttaccgtagt acggttactg acttcgtcag
    12301 ttctatccac aacctcaaaa cagtattttg agcagcctac ggctagcttc ctagtttgct
    12361 ttttgatttt tattgagtat gaaaaggatt ggagaaagcc ttccagcttg tggtataata
    12421 gatttatgga taaaaaatat gaaaaaatct ctcaggattt gggagtgacg ttaaagcaaa
    12481 ttgataccgt tctaagtttg acagctgaag gggcgactat tccctttatc gcgcgttatc
    12541 gcaaggacat gactggtagt ctggatgagg tggcgattaa ggctattatt gatttggata
    12601 aaagtctgac aaatctcaat gaccgtaagg aagctgtctt agctaagatt caagaacaag
    12661 gtaagttgac caaggaattg gaagaagcta tcttagttgc cgaaaaatta gcagacgttg
    12721 aagaactcta tcttccttat aaggaaaagc gtcgtaccaa ggcaaccatt gcccgtgaag
    12781 ctggactctt tcctcttgct cgcttgattt tgcagaatat agttgactta gagaaagaag
    12841 ctgaaaagtt cgtctgtgaa ggatttgcga ctggcaagga agccttgacc ggtgcagttg
    12901 atattttggt cgaagcctta tcggaagatg tgaccttgcg ttctatgact tatcaggaag
    12961 tgctgagaca ctctaaactc acttctcaag ccaaggatga aagtcttgat gaaaagcagg
    13021 tttttcagat ttattatgat ttttcagaga cagttggaac tatgcaaggc tatcgtacct
    13081 tggctctcaa tcgtggggag aaacttggtg tcttgaagat cggttttgaa catgcgacgg
    13141 accgtattct tgccttcttt gctactcgtt tcaaggtgaa aaatgcttat attgatgaag
    13201 ttgttcagca atccgttaag aaaaaggtct tgcctgctat tgagcgtcgt attcggacag
    13261 aattaactga gaaagctgaa gagggagcta tccaactttt ttctgacaat ctgcgcaatc
    13321 tcctcttggt tgctccactg aaagggcgcg tggttcttgg gtttgaccca gcctttcgta
    13381 caggtgccaa gctagctgtc gtggatgcaa caggaaaaat gctgacaact caggttattt
    13441 atcctgttaa accagcatca gctcgtcaaa tcgaagaagc caagaaagat ttagcagatt
    13501 taattggtca atacggtgta gagattattg ccattggaaa tggaacggcc agtcgtgaaa
    13561 gtgaagcttt tgtagcggaa gttctgaaag atttccctga agtcagctat gttatcgtta
    13621 atgaaagtgg tgcttctgtc tattctgcca gcgaacttgc tcgtcaggag tttccagact
    13681 tgaccgttga aaaacgctct gccatttcta tcgcccgtcg tttgcaagat cctcttgcgg
    13741 aattggtcaa aatcgatcct aagtcaattg gtgtcggtca ataccaacac gatgtcagtc
    13801 agaagaaact ctctgagagt ctggactttg ttgtcgatac agtggttaac caagttggtg
    13861 tcaatgtcaa tacagctagc ccagctcttc tttcacacgt agctggactc aataaaacca
    13921 tttctgaaaa tatcgtcaaa taccgtgagg aagagggaaa aatcacttca cgctcccaaa
    13981 tcaagaaagt tcctcgtttg ggggccaagg cttttgaaca ggctgctggt ttcctccgta
    14041 tccctgaaag tagcaatatc cttgataata caggagttca tccagaaaat tacgctgccg
    14101 ttaaggaact cttcaaatgc ttggacatta aggatctgaa tgaagaggcc caaagcaaac
    14161 tcaagtcgct ttcagtcaag gaaatggcgc aagagttaga ccttggtcca gaaactctta
    14221 aagatatcat tgcagatctt ctcaaaccag gtcgagattt ccgtgattcc tttgatgctc
    14281 cagttctccg tcaagatgtc ctagatatca aggacttagt ggttggaaaa aagctagaag
    14341 gagtggtgcg taacgttgtt gatttcggtg cttttgttga tatcggaatt catgaggacg
    14401 gtctcatcca tatttcccat atgagtcgca agtttatcaa acaccctagt caagtggtgg
    14461 cagttggaga tttggtgagc gtttgggtta agaaaattga tactgaacgt gaaaaagtta
    14521 atctgtctct cctagctcca aatgaaactg actgattacg tcaagcaggt ttcactagaa
    14581 gacttcggca gaccttttat ccatcatgtc cagtggaata ggcgtctacg ttcgacaggt
    14641 gggcgatttt tccccaaaga tgggcatttg gattttaatc ccaaggttta tcaggaactg
    14701 gggttggacg tttttaggaa aattgtccga catgaactct gtcattatca cctttatttc
    14761 caagggaagg gctatcaaca caaggatcgg gattttaagg aacttttgaa agcagtggat
    14821 ggattacggt ttgtaccatc cttgcccaat agtaactcta aaccactcaa gctttatcgt
    14881 tgtcaatcct gccagcaaag gtatcagcgc aagcgtagga ttgataccaa acgctatcgc
    14941 tgtggacttt gtcgaggtaa attgcttctg ataaatcagc ctgaggactg atgaaagccg
    15001 agcctccccg tgatatacta tgtctaacct agcagaaaga ggaaatatca tgaacagtaa
    15061 attttataaa atgagacgca atcgcatgat ttcaggagtt ctggcaggtc tgtcagacaa
    15121 gtggaatttt gatgttaccc tagttcgttt cttgtttgcc atttttacag ttgcaaactt
    15181 tggacttggc gtgattatct atatcatcct agcttctatc atgcctacca aggaagaaat
    15241 cgaagcagaa atgtacggaa caggcccacg taaacgcaaa gaagcccaag ccattgacga
    15301 caatgaaggc aggttttggt gaggttctac agaagatttg gaataagcaa aaagctttaa
    15361 atcaatagtc taaactgctt gatttaaagc ttttttactt ttatactcaa taaaaatcaa
    15421 agtgcaaact aggaagccag ccacaggctg taatttagtc ggcaatgtga agttgacata
    15481 gtttgcactt tgatttttga atagtattaa taatatttcg ccagcttcat ccacaaacta
    15541 tagtggattg gaactagaat agtacacctc tacttctaaa acattgttag aaatcgattt
    15601 gactatcctg atcgatttgt cctgttctta tttcatttta ttataaaagc agtaatttaa
    15661 actcagtttt ttaatctatt tttgctgctg agacaataca tttttggaaa aatggtggat
    15721 gctgataaca actgataacc agcaaataac ataagcagtg ccggtaaatt ctgtaccgat
    15781 aaagtgtgtg tgttcaacta agagctgacc gatgaatgga gagagcagat agagaagtcc
    15841 gatgagtata tgttctttgt gtttcattaa agcgcacctt ctttccttat aggttgaacg
    15901 acttgcaagt gttaaattga atggtatgtt atctaggtaa ccttactaaa atgttagttc
    15961 ccgcttcctc cttttcaaag taagcctttt cacacttata ttttacaact ttaaaaatag
    16021 gaaatcaaat cattttctaa gtaattttgc ttatatttca cccaatctta caaaaatgta
    16081 agattaaagt ctcttttgta aggttaggtt atggcaagcg gtcttttttt gatgtaaact
    16141 agactcataa agaacaaagg agtaacatca tgaaacaaat cttacataag aaaactagaa
    16201 aaccaagtca caaagaaatt gagcgcgttc agctgggatg cactatgatg caagctacat
    16261 ttcatttgat gggatattaa gaaaggagat tctcatgaca cttttagatg taaaacacgt
    16321 tcaaaaaatt tataaaacac gttttcaggg caaccaagta gaagccctca aggatattca
    16381 ctttaccgtc gaaaagggtg actacgttgc catcatgggt gagtctggtt ctggtaaatc
    16441 aactcttctc aatattctag ctatgctgga taaaccaagt cgtggtcagg tttacttgaa
    16501 tggaactgac accgcaacca ttaaaaattc acaggcctct agcttccgtc gtgaaaagtt
    16561 gggctttgtc ttccaagact ttaacttgct agatactcta tctgtaaagg acaatatctt
    16621 gcttccgctt gtcttgtcaa gaagacctat tacagagatg atgaagaaat tggtggtgac
    16681 agctgagaat ctgggaataa accaattaca agagaagtac ccttacgaga tttctggtgg
    16741 ccagaaacag cgtgtagcag tagcacgcgc catcatcact gaacctgaaa ttctccttgc
    16801 ggacgaaccg acaggagctc ttgactccaa gtcatctgca gccttacttg atgtctttga
    16861 tgaaatcaat gagcgcggcc aaaccattct catggtaacc cactcaacag cagcagctag
    16921 cagagctaaa cgtgtactct ttatcaaaga cggcattctt tacaatcaaa tctaccgtgg
    16981 agagaagaca gaacgtcaga tgttccaaga aatctctgat accttgactg tcatggcaag
    17041 cgaggtgaat tagtatgttt cgattaacca ataagttagc ggtattgaac ttgattaaaa
    17101 accgcaaact ctactatcct tttgcgctgg ctgttctctt ggcagtcact ctcacctatc
    17161 tcttttactc tctaaccttc aatcctaaga ttgcggaaat ccgtggagga acaaccattc
    17221 aggctacact tggatttggt atgtttgtcg tcacccttgc gtcagccatt atcgttctct
    17281 atgccaatag ttttgtcatg aagaaccgtt ccaaggaact aggaatttat ggcatgttgg
    17341 gcttggagaa gcgtcatctt atcagtatga cctttaagga gttagtggta tttgggattc
    17401 taactgttgg agcgggtatc ggtattggag ccttgtttga caagttaatt ttcgctttcc
    17461 tgctcaaact aatgaaattg aaggttgagc tggttgctac cttccagacg aaagttatca
    17521 ttacagtgct tgttgtcttc ggtttgattt tcctaggcct catgttcctg aatgcccttc
    17581 gaatcgcccg tatgaatgcc ctccagctct ctcgtgagaa agctagtgga gagaaaaaag
    17641 gtcgcttcct tcctctccaa accattcttg gttccataag tttaggaatt ggctattatc
    17701 ttgcccttac ggtaaaagat cctcttacag ccttaacaac cttcttcata gctgttttac
    17761 tggttatctt tgggacttat ctcttgttta atgcagggat taccgttttc ctccaaatct
    17821 taaagaaaaa taagaaatac tattaccaac caaataacct catatctgtt tctaacttga
    17881 ttttccgtat gaagaaaaat gcagttggac tagcaactat cgctattttg tcaacaatgg
    17941 ttttggtaac catgtcagca gcgacaagca ttttcaattc cgcagaatcc tttaaaaaag
    18001 ttctaaatcc tcatgatttt ggggtttcag gacaaaatgt tgaaaaagaa gatttggaca
    18061 aactcttgag ccagtttgca agtgacaatg gttataagat taaagaaaaa gaagtgtttc
    18121 gttacactta ctttggtgtt gcgaaccaag aaggaaataa gttaaccttt tttgaaaaag
    18181 gacaaaatcg tgtccaaccc acaacagttt tcatggtatt tgaccaaaaa gattatgaaa
    18241 atatgactgg tcaaaaactg tctctatcag gaaatgaggt cggtctcttt gccaaaaatg
    18301 acggactgaa aggacagaaa gctctaactc taaatgatca tcaattttct gtcaaagaag
    18361 aatttaataa agatttcatt gtcaaccatg ttccaaataa gtttaatatc ttgactactg
    18421 attacaatta ccttgttgtt cctgatttac aagccttttt ggatcaattc ccagattcgg
    18481 ctatctataa tcagttttac ggtggtatga atgtagatgc cagcgaagaa gaacaactca
    18541 aggtcgctga ggagtatgaa aactacctca atcaatttaa tgctcaatta gacacagaag
    18601 gtagctatgt ttatggtagc aatctagcag atgctagttc tcagatgagt gccctctttg
    18661 gtggtgtctt ctttatcggt attttcctat ccattatctt tatggtcgga actgttctgg
    18721 tcatctacta caaacaaatt tctgaaggct acgaagaccg tgaacgcttt attatcttgc
    18781 agaaagtcgg tttggaccaa aagcaaatca agcaaaccat caacaaacag gttttaactg
    18841 ttttcttcct tcctttgctc tttgccttca tacatctcgc ctttgcctac catatgctta
    18901 gcctgatttt aaaagtgatt ggtgtactgg atacgactat gatgttgatt gtgaccttgt
    18961 ctatctgcgc tatcttcctc atcgcctatg tgctgatttt catgattact tcaagaagtt
    19021 atcgcaagat tgtgcaaatg taaaaaagat acctcgactt caaaatcgag gtatttcttg
    19081 tattctaaat gctgaaaagt tgttcgagca ggaaggtaac tcccatggtc aagagaccaa
    19141 tagcaaggtt ccgaatcata gctgttctag tcggatcctt tccaagtctg gcactagtgt
    19201 aaccagtgag aagaagggcc acaccgacaa taaggacagt agcagggatg cgatattcac
    19261 ttgggaatat ggtcactgac agcattggag gcaaacttct aaggaaaaag gcaacgaagc
    19321 tagaaatggc agcgtgccaa ggattggtaa attcttcata ctcaatccca tatttttcct
    19381 ctaccagagc cttgagtgga tttttaagaa agatcttatt ggtcaagagt tgggcagaag
    19441 ttttgcattc tccattttgg atataagcag catagaggga ttttttggct agttccctat
    19501 cttggtctaa caagagtttt tctcgcgaaa cggcagcttc ctcggtatct tttggagttg
    19561 aaacggatac atattctcca ccagccattg aaaaggcacc agctaagata gccgcaaatc
    19621 ctgataaaaa gataatccag atattggtcg tggcactggc aaccccgata accacaccag
    19681 caatggaaat aattccatcg ttagcaccaa gaacacctgc gcgcaggata tttaaacgac
    19741 ctgcaaaatt tgaatcgatt tcgtgatttg tttctgacgc taaatttcaa gttcaagtta
    19801 gccatccaga agtcttctct gggtgacttg tagtccaagc attttttagg atagttgtta
    19861 atccactttt cgatgaatgc gacttctttg ggagtcattt tcttggttcc cttaggtaac
    19921 catctacgaa tgagcctgtt gtgattctca ttagttcccc tttcccaaga ggcatagggg
    19981 tgcgcataat agatgtgctc ctcagaaaat acatcaaaca agcgattgaa ttccgttcca
    20041 ttatctgccg tgatggaaag aatcttgtgt tgttttaaga tgagttttag agcctgattg
    20101 accacctcag cacttttatt tggaatcaat cggatgatct gatgtctact ctttcgatcc
    20161 gtcaagacaa gcaagcagta gtttttcgct ctcgtaagta gaaccgtatc aatctcataa
    20221 tgcccattct ccaagcgaag attgatagct tcagaccgct gttcgataga ttgaccag
//
LOCUS       DBERDS010000035        19955 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.035, whole genome shotgun sequence.
ACCESSION   DBERDS010000035 DBERDS010000000
VERSION     DBERDS010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19955
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.035"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..1099)
                     /gene="phtB"
                     /locus_tag="ACL73E_001435"
     CDS             complement(<1..1099)
                     /gene="phtB"
                     /locus_tag="ACL73E_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGS0801393.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPS"
     gene            complement(1257..3707)
                     /gene="phtA"
                     /locus_tag="ACL73E_001436"
     CDS             complement(1257..3707)
                     /gene="phtA"
                     /locus_tag="ACL73E_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGS0801394.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQTSQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3960..5693)
                     /gene="ptsP"
                     /locus_tag="ACL73E_001437"
     CDS             complement(3960..5693)
                     /gene="ptsP"
                     /locus_tag="ACL73E_001437"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGS0801395.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(5699..5962)
                     /locus_tag="ACL73E_001438"
     CDS             complement(5699..5962)
                     /locus_tag="ACL73E_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGS0801396.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            6313..6531
                     /gene="nrdH"
                     /locus_tag="ACL73E_001439"
     CDS             6313..6531
                     /gene="nrdH"
                     /locus_tag="ACL73E_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGS0801397.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            6612..8771
                     /gene="nrdE"
                     /locus_tag="ACL73E_001440"
     CDS             6612..8771
                     /gene="nrdE"
                     /locus_tag="ACL73E_001440"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGS0801398.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            8959..9921
                     /gene="nrdF"
                     /locus_tag="ACL73E_001441"
     CDS             8959..9921
                     /gene="nrdF"
                     /locus_tag="ACL73E_001441"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGS0801399.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            10103..10864
                     /locus_tag="ACL73E_001442"
     CDS             10103..10864
                     /locus_tag="ACL73E_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGS0801400.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11149..11400)
                     /locus_tag="ACL73E_001443"
     CDS             complement(11149..11400)
                     /locus_tag="ACL73E_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGS0801401.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQMPCLTSEELKSLGKWYVSTGK
                     EWICHSDADLEEFKNLFLNFINPEEWDTISFDSDFMPFQ"
     gene            complement(11443..12849)
                     /gene="lacG"
                     /locus_tag="ACL73E_001444"
     CDS             complement(11443..12849)
                     /gene="lacG"
                     /locus_tag="ACL73E_001444"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGS0801402.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(13064..14758)
                     /locus_tag="ACL73E_001445"
     CDS             complement(13064..14758)
                     /locus_tag="ACL73E_001445"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGS0801403.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(14760..15077)
                     /locus_tag="ACL73E_001446"
     CDS             complement(14760..15077)
                     /locus_tag="ACL73E_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0801404.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(15113..15949)
                     /locus_tag="ACL73E_001447"
     CDS             complement(15113..15949)
                     /locus_tag="ACL73E_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGS0801405.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(16183..17163)
                     /gene="lacD"
                     /locus_tag="ACL73E_001448"
     CDS             complement(16183..17163)
                     /gene="lacD"
                     /locus_tag="ACL73E_001448"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGS0801406.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(17165..18094)
                     /locus_tag="ACL73E_001449"
     CDS             complement(17165..18094)
                     /locus_tag="ACL73E_001449"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGS0801407.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQDPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            complement(18105..18620)
                     /gene="lacB"
                     /locus_tag="ACL73E_001450"
     CDS             complement(18105..18620)
                     /gene="lacB"
                     /locus_tag="ACL73E_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGS0801408.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHHESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(18651..19076)
                     /gene="lacA"
                     /locus_tag="ACL73E_001451"
     CDS             complement(18651..19076)
                     /gene="lacA"
                     /locus_tag="ACL73E_001451"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGS0801409.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(19233..19730)
                     /locus_tag="ACL73E_001452"
                     /pseudo
     CDS             complement(19233..19730)
                     /locus_tag="ACL73E_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            complement(19746..>19955)
                     /locus_tag="ACL73E_001453"
     CDS             complement(19746..>19955)
                     /locus_tag="ACL73E_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0801410.1"
                     /translation="PRKSSKLKSLIAEDKAYNHALSKERSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLSAGIINHELGF"
BASE COUNT         5902 a         4104 c         3578 g         6371 t
ORIGIN      
        1 gacttggact aggttccgga gtcgattgtg gacttggttg ttctggtctt gaatctggta
       61 cccaatggtt tgaacgataa cgaaggggaa taatacgagc aattcgtttt tccaattcag
      121 acatttgttc ataagggata aagtggtaat ggttaccatg agggacagct acacctctgg
      181 cggttcgact tgtgatttgc gctgggtcga aaataaggcc atcagattcc acatggcgtt
      241 ctgataaggg tttagcatac aattcacgta aaaggcttga aatgttttcc ccttgatttt
      301 gatgataagt tggagtgaca gtcagattgt ggttctctga caatcttggt tgagctggat
      361 ttgcattata actagaactt gaagaaggac gagatccctg cttcccattc caataggctt
      421 ctgcagcagc taactcgcta gctgataact cattcttagg aatgtaatgg taatggtcgc
      481 cgtgaggaac gatataagca tcacccgtgt cctcaatgat atcagatgca ttgaagatat
      541 acccatcatc cgttgtataa cgtccttggg ctctggctgc agcaacagca ttatctgctc
      601 ttgagttatg attatgactg cgttcctgct tctgacgttt aatctcttct tttgtccgaa
      661 tattatccgc atgagctgca tccttaaggt aaacatagta tttaccgttt accttaagga
      721 cataaccacc cttgatttca ttgacaatgt ctgaatcctt caactgataa ttcggatctt
      781 tcatgaggag ctcttcactg atgatggcat cataaggaac cttgccatta tagtaatgat
      841 aatggtctcc atgagaggtc acataacctt gatccgtaat cttgataaca atttgttcgg
      901 cgttgatccc ctccctctta ctgacttcat ctggtgtcaa gttttctgcc ttttgaccag
      961 cctgatcacc atctatataa gcaactcgat tagactcttt cttatcctga ccagcttggt
     1021 aacgtccaag ctcataggaa caaacactta gggcaaggac tgccactgaa cctgctagat
     1081 attttttatt gattttcatt ctttcctctt ttcttaagta tatttgattc actataaagt
     1141 aataaaccgg ttaattaact agttaatagt ttactctttt taatattgct tgtcaagaat
     1201 tttacatata tacataataa aaatgaaagc ctctttatcg agactttcat ttttcattag
     1261 tttatttttt ccttacttac agatgaagga ttacttcctt ttaacaacgc aagtaatttt
     1321 tctgcttctg ccatgatact attgttatcc ataatttgaa gagtcaaatt atttcgtaaa
     1381 ccagctagag tttctgttgc attggctttc agactagaat ccgttacttt cgcaagcaaa
     1441 acttctgctt ctttgagttg ggcttctact ttttcagtct ctacttgagg gacttctggc
     1501 tcagcaggtg tttcctctac tggctcttca tccgctttga agttcttatt tggatcttca
     1561 ctgtggtctt tcttgcctaa cacatgctca ctggcattgc cccatccatc attagaatgt
     1621 ggacgttcgt cagggtgttc tacgtagtac ttaatcgtcg caaacaaatc ttccaaggta
     1681 tagccatttg gagctttgta tgtgtgatca tcaaaccaag caaatttaat gttatggtaa
     1741 tgatccttat gaggaataat caaattaccg tttttaacct caactgtatg ctcaaccata
     1801 tatggaagtc gaacgagtgg aattcgtttt tcccctttca cacgattgta aatagctgct
     1861 gcactatctc cagttggatt tgctttaaca tctgcgtctg gagatggagg taggatacct
     1921 ttttctttag tataggcttg agctgcaact ttttccttat cagaaaggct gtcttttcca
     1981 atccagtgac tatggcccat atgaggcgtt acatatgcat ctccttcatc actgattata
     2041 tcatgttcat caaaaatata accatctgac gttgtatact tatcagctaa ttgagcaata
     2101 cgaacttcgt cttcagtata ctcaatttga gaatttggct tgccaagtcg ctctggatgg
     2161 gtaattggtg ctaggaatgc caataaatca tctaccaatt tttctttatt agtcgattca
     2221 tcattcaagc gttctaataa tttgtctaag gcttggaaat cagaattacg acccttattt
     2281 tcaaacaagg ctttatgagc ctcagttaac agattatatg ctttatcata aaattcttgg
     2341 tcacgaggag caacattttc ttttttagca gttaaagtgt gtgaaacact ctcttgtttt
     2401 gataacttgc tttcaagatt tttaacagtt tcagatggta aatctttcgc aaagacataa
     2461 cgagagatgc ccttttcttc gaatacatat ccttccccaa cttttcgtac cagctgacta
     2521 accaaagaag aatttgagtc tattttaaga tttggtgcag gttgcgggcc tggactaggt
     2581 tccggagtcg gttgtggact tggttgttct ggccttgaat ctggtaccca atggtttgaa
     2641 cgataacgaa ggggaataat acgagcgatt cgttcttcca attcagacat ttgagagtaa
     2701 gggatgaagt ggtaatgatc tccgtgtggc actgcaacac ctctagctgt tcgacttgtg
     2761 atttgcgctg ggtcgaaaac aaggccatca gattctacat gtcgttgact caaaggcagt
     2821 ttgtagagct gtttcaagag actatcaatg tcattacttt gacttgtttg actgttagtg
     2881 ttgctgttgt tgcttgtgtt agtatttgta gttcctggat tgcttacaga aggtacccag
     2941 tttgttcttg aagtgttatc gctattttgt cggcgatagg ttcttgaatt tgacagattt
     3001 ccccgaccag ataggaaggc ttctgcagca gccaactcgc tagctgataa ctcattctta
     3061 ggaatgtaat ggtaatgatc tccatgagga acgatataag catcaccagt atcctctatg
     3121 atatcagaag cattaaagat ataaccatca tctgtagtat agcgtccttg cgaacgtgcc
     3181 aaggcaacag caccatcgtt tcttggagtc ccaccttcac gatgttgact atgttcttgt
     3241 ttttgtcgat tgatttcctc ttttgtacgg acgttatccg cgtgggcagc atccttaagg
     3301 taaacatagt attttccatc taccttgata acatatccac ccttgacctc attaacaata
     3361 tcctcatctt ttagcttata gttcggatct ttcatgagta attcttcact gaaaatcgca
     3421 tcataaggaa ccttaccatt gtaataatga tagtggtcgc catgtgaagt gacatagcct
     3481 tggtctgtta tcttgatgac gatttgctca gcattgattc cttcacgctt gctaacctca
     3541 tcaggagtca aattctccgt tttttgcgtc gcttgttttc catctatata ggaaacacga
     3601 ttattttcct taaccgttct agcttgatac agtcccaact cgtaagaaca aacacttaaa
     3661 atcaaagctg ccgcagaacc aacaaggtat ttcttattaa ttttcatcga aactctcttt
     3721 ctatttgata tttctagttg caattcattt ctaaattgca gaaactcctc tctattactt
     3781 aactggttaa tagtttactc ctaaatctcc aacttgtcaa gaattttatg aaccatttaa
     3841 gtattttttg ttctgactac tactttttca agaaaatctt tctataagaa agattttctt
     3901 gaaaattctt tttaaaatat caaaaaaatc cctgtaactg agttgcaggg acttttcgat
     3961 taatcaaaat taacgtattc tttttgaagt tcaagaactt cttccattgt tgagcattct
     4021 gtaagggcac ggtttgcgta ctcttccatc ttagctgtgt cgagtttctt catcaagctg
     4081 cgtgtacgaa gtacagatgt tgctgacata gagaactcat ccaagcccat tccgacaaga
     4141 agtggaacag cttgttggtc accagccatc tcaccacaca taccagccca tttaccttca
     4201 gcgtgagctg ctttgatcac attgttaatc aagcgtagga ttgatgggtt gtatggttgg
     4261 taaaggtatg aaacttgttc gttcatacgg tctgctgcca ttgtatattg gatcaagtcg
     4321 tttgtaccaa ttgagaagaa gtcaacttct ttagcaaatt ggtctgcaag catagccgct
     4381 gcaggaatct cgatcatgat accaacttgg atgttatccg caactgcaac accttcagca
     4441 agaaggtttg ctttttcttc atcaaagact gctttcgctg cacggaattc tttcaagagc
     4501 gcaaccattg ggaacatgat acgcaattga ccgtgaacag acgcacgaag aagagcacgg
     4561 atttgtgtgc ggaacatagc atctccagtc tcagagatag agatacgaag agcacggaat
     4621 ccaaggaatg ggttcatttc gtgaggcata tcgaagtaag gaagttcctt atctccaccg
     4681 atatccattg tacgaacgac aacaggttta ccgttcattc cttcaagaac agccttgtat
     4741 gcttcatact gctcatcttc agttgggaag tcttgagaat ccatgtacaa gaactctgta
     4801 cggtaaagtc caacagcttc tgcaccgttg ttgttaacac cttcaacgtc ttttggagta
     4861 ccgatattag cagccaactc gaagtgttta ccgtcagcag tcactgtttg agcatctttc
     4921 aagagcgccc attcagcttt ttgtttcgca taagcttcac cagctgcttt aaattctgcc
     4981 gcttgttcat cagttgggtt gataataacc tcaccagtga tcccgttaac agcaaggatg
     5041 tcaccgtctt taacgatttc agtgatgttg tttgtaccta atacagctgc aatttcaagt
     5101 gtacgtgcca tgatagctga gtggcttgta cgtccaccga tgttggttac aaaagctttt
     5161 acaaagtttt tgtccaattg agctgtatca gatggtgtca agtcatgtgc aatcacaatc
     5221 acttcttcat tgatagaagc tgggtttggc aattttttac caagaaggtt tgccaataca
     5281 cgttttgtca catcgcggat atccgctgcg cgttcttgca tgtatgggtt gtcttccatg
     5341 ccttcaaaga tagtgataaa catatctgta acttctttca gacctgcttc tgcattcact
     5401 ttcttcgcac ggatagtttc cttgatttgg ctgatcattt ctgggtcagc aagaaccatt
     5461 aagtgagcat caaaaacttg agctgcttct tcaccgagcg tacctactgc tttctcgcga
     5521 ataacagaaa gctcgtcttg tgatgcctgt agagcggcat caaggcgagc ttcttctgcg
     5581 tttgtatctt cgactgtaat agtctcaaat gacaaatccg gctgaacgag tagatatgct
     5641 tttgcaactg caacaccgtc agatgctgcg attcctttaa gcatttctgt catttccctt
     5701 atgccaatcc ttctttttcc attgtttctg agattgcagc gatagcgtca tctgcatctg
     5761 caccttcagc tgagatagtt acgtcagcac cttggccaac accaagactc ataacaccca
     5821 taattgattt aaggttaact gatttacctt tgtactcaag agtgatatct gaagcaaatt
     5881 tgctagcagt ttgtaccaac aatgttgctg gacgtgcgtg aatacctgtt tctgccacta
     5941 cgtggaaatc tttagaagcc atagtttgac tctccttttg ttctttcttt ttttgagtta
     6001 tatgtgataa cccttacaat ttagtattat accatcttct aggatttttt tcaagcattt
     6061 tctggatttt ccttcaattt cctttcagat aacttgctga aaatcttcta tcctagataa
     6121 caaaacacag gatatagttt ctttaaaaac aatttatagg ataatcattg ctatttcaca
     6181 atacaaacac tatatattgt gtttatatat aaaaacaaca aaagaacacc actatattta
     6241 gttcaaatca ttgacaaaat tttattttct gatatactaa gatagtatta aattttgaag
     6301 aggagttaca caatggtaac cgtttattct aaaaacaatt gtgtccaatg taaaatgacc
     6361 aagcgtttct tggacagtaa taatgtctct tatcgtgaaa tcaatcttga tgagcaacct
     6421 gagtacgtcg atcaagttaa agagctcggt tttagcgcag ctcctgttat ccaaacacca
     6481 actgaagtct tttcaggttt ccaaccagga aaactgaaac aattagcata atcttagtac
     6541 atcatccaga agaaactgct tttagggcta acttagaagc ctttcttttg taattagata
     6601 agggaaattt tatgggatta aaacatcttg aagacgtgac ttacttccgt cttaataacg
     6661 aaattaaccg tcctgttaat ggacaaatca tgcttcataa agataaggaa gccttggatg
     6721 ctttctttaa agaaaatgta gttccaaaca ctatggtttt tgattcaatc aaagacaaaa
     6781 tcaattacct cattgaacac aactacatcg aaacagcctt tatcaagaaa taccgtccag
     6841 agttcttgga agaattggct caatttatca aagaccaaaa cttccaattc aagtcattca
     6901 tggcagctta taaattttac aatcaatatg ccttaaagac taatgacggt gaatactatc
     6961 ttgaaaatat ggaagaccgt gtcttcttca acgcccttta tttcgctgat gggaatgaag
     7021 ctgttgcaat cgatattgcc aatgaaatca tccaccaacg ctaccaacct gctactcctt
     7081 ccttcttgaa tgctggacgt gctcgtcgtg gggagttggt atcttgtttc ctaatccaag
     7141 tgacggatga tatgaactct atcggacgtt ctatcaactc agctcttcaa ctttcacgta
     7201 ttggtggtgg tgtgggaatt accctcagca accttcgtga agctggtgca cctatcaaag
     7261 gctatgaagg agctgcttca ggtgtcgttc ctgttatgaa gctttttgaa gacagcttct
     7321 cttactccaa ccaattgggg caacgtcaag gtgctggtgt tgtctacctc aacgtctttc
     7381 acccagatat catcgctttc ctttcaacta agaaagaaaa cgctgatgaa aaagtacgtg
     7441 tcaagactct atcacttggt gttgtagtac ctgataaatt ctacgaattg gctcgtaaaa
     7501 atgaagaaat gtacctcttc agcccttact ctgtagaaaa agaatacggt gtgccattca
     7561 attacatcga cattactgaa aaatacgatg aattggtcgc aaatccaaat attcgcaaga
     7621 caaaaatcaa ggcgcgggat ttggaaactg aaatctctaa attgcaacaa gagtctggct
     7681 atccttatgt agtcaacatc gatacggcta accgtgcaaa tcctgttgat ggaaagatta
     7741 tcatgagtaa cttgtgttct gagattcttc aagttcaaga accaagcttg atcaacgatg
     7801 ctcaagaatt ccttcaaatg ggaacagatg tttcatgtaa tctgggttca accaacgtgg
     7861 ttaacatgat gacttcacct gattttggtc gttctatccg tgctatggtt cgtgccctta
     7921 ctttcgttac agatagttca catatcgtag ctgtaccaac gattgaccat ggaaatagcc
     7981 aagcccacac ctttggtctc ggtgccatgg gactgcacag ctaccttgcc caacaactca
     8041 ttgaatatgg ttcacctgag tctgttgaat ttacaagcat ctactttatg cttatgaact
     8101 actggacctt ggtagagtca aacaatattg cgcgtgaacg tggtattacc ttccacaact
     8161 ttgaaaaatc agactatgct aacggaagtt actttgacaa gtatgtaact ggtgaatttg
     8221 ttccaacatc agaccgtgtt aaagaactct tcaaaaatgt ttttatccct ggtgttgctg
     8281 attgggctga acttcgcgac aaggttcaag aagatggtct ttaccaccaa aatcgccttg
     8341 ctgtagcgcc aaatggttct atcagctata tcaacgacgt ttctgcttct atccacccga
     8401 ttacgcaacg tatcgaagaa cgccaagaga agaaaattgg taaaatctac taccctgctg
     8461 ctggcttgtc tacagaaacc attccttact acacttctgc ctacgatatg gatatgcgta
     8521 aagtcatcga tgtttacgct gctgcgactg aacacgtgga tcaaggactt tcactcaccc
     8581 tcttcatgcg cagtgacatt ccaaaaggcc tttacgaatg gaagagggaa aataaacaaa
     8641 cgacacgtga tttgtccatc cttcgtaact atgcctttaa caagggaatc aagtctatct
     8701 actacgtccg tacctttaca gatgacggtg gagaagtcgg cgccaaccaa tgtgaaagct
     8761 gtgtgattta gtttctagca tagaaacatt atttttccct aagcagcact gataaaatca
     8821 aatctactat gtcataacat aatttatgta acattttaaa agtcgggctt ccgacttttt
     8881 gtgcgatact cctatagaat tatggtaaag tagaaataat tgtgagttcg caatactaaa
     8941 cacagaaaga gattttaaat ggaaacttac tacaaagcca ttaactggaa tgccatcgaa
     9001 gatgtcatcg acaaatcaac ttgggaaaaa ctgacggagc aattttggct cgatacacgt
     9061 attcccttat caaacgactt ggatgactgg agaaagctat ctaacaaaga gaaagacttg
     9121 gtcggaaaag tttttggtgg tttaaccctt cttgacacta tgcaatctga aactggggtt
     9181 caagcccttc gcgcagacat ccgtacacca catgaggaag ctgttttcaa taacatccaa
     9241 tttatggaat ctgtccacgc taaatcttac tcatcaatct tttctacctt gaatactaag
     9301 gctgagattg aagaaatttt cgaatggacc aataccaatc cttacctaca aaagaaggct
     9361 gagattgtca acgaaatcta cctaaacggc agcccacttg aaaagaaagt tgccagcgtc
     9421 ttcctcgaaa ccttcctctt ctactctggt ttcttcactc ccctctacta tctcggtaac
     9481 aacaaactag ccaacgttgc agaaatcatt aaattgatta ttcgtgacga gtctgttcac
     9541 ggaacctaca ttggttacaa attccaactt ggtttcaatg aattgcctga agaagagcaa
     9601 gaaaaactca aagaatggat gtacgaccta ctctatactc tttatgaaaa tgaagaaggc
     9661 tacacagaga gtctttatga cggtgttggt tggactgaag aggttaaaac cttccttcgc
     9721 tacaatgcca ataaagctct catgaacatg ggacaagatc cacttttccc agattcagct
     9781 gaagatgtca acccaatcgt tatgaacggt atttcaacag gaacttccaa ccatgacttc
     9841 ttctctcaag tcggaaatgg ttaccttctt ggcgaagttg aagccatgca agacgatgac
     9901 tataactacg gtttagacta attctccatc actctcaatc atcaaaaagt aaactagaaa
     9961 catcaaagtt ataacccaac aaaaatatcg aaagttttga aaacaaactt cgatattttt
    10021 gtttttgttt cattttgttg tttttgtatt tgaatgatga gtttgtttat ggtaagatag
    10081 tagtaggaaa cgaggtgata atatgctcaa acaagaaaaa ttaaccaaaa ttttagagat
    10141 agtaaatagt aaaggaacca taacagttaa acagattatg gacgaaatag ccgtttcaga
    10201 tatgactgca aggcgctatt tacaggaatt agctgataaa gatttgctga ttcgtgtgca
    10261 tggtggagct gaaaaacttc gaaccaactc ccttttgact aatgagcgat caaatattga
    10321 aaaacaagcc ctccaaacgg cagaaaaaca agaaatagcc cattttgcag gcagtctagt
    10381 agaagaaaga gaaactattt tcattggacc aggaacaaca ttagagtttt ttgcgcgtga
    10441 gttgcctatt gacaatatcc gcgtcgtaac caacagtcta cctgtttttc tgattttaag
    10501 cgaacgaaaa ttaacagatt tgattttaat aggtggaaat tatcgcgata ttacaggtgc
    10561 ttttgttggt acattgaccc tacaaaatct ctctaatctc caattttcta aagctttcgt
    10621 tagctgtaat ggtattcaaa acggagctct agctactttt agcgaggaag agggagaggc
    10681 tcaacgcatc gctttaaata attctaataa aaaatattta ctcgcagatc atagtaagtt
    10741 caataagttt gatttttata ctttttataa tatatcaaat cttgatacta ttgtttcaga
    10801 ttctaaacta agtgattcaa tcctttttaa gctatctaaa cacattaaag tcatcaagcc
    10861 ttaataaact gaaagagcct gggtaacaac tcaatttcag aagaaaaaaa gtaaatcttc
    10921 ccacaataaa aagcatagta tcaggtgttg aaacacctga tactatgctt ttttctatat
    10981 caaagacttt ttgcccaatt cctcaaagct atacattgag aaatctgcga ctcgcttcct
    11041 agtttaaagt tgctctttga ttttcattga gtataagcaa cgtgattaga taagagtttt
    11101 acagagtact aaatataaga tttaactttt ttgagaaatt ggttacgatt attgaaacgg
    11161 cataaaatct gaatcaaagg agatagtatc ccattcttca ggattgataa aatttaaaaa
    11221 tagattttta aattcttcca gatcagcatc tgaatgacaa atccattctt taccagtcga
    11281 gacataccat tttccaagac ttttcaattc ttcactcgtc aaacacggca tttgagagca
    11341 tttttcgaaa tttataatat aaactttttc ataaatagat tggataaaat ctttgaacat
    11401 ctttttgact tactaaaatt ctatatctaa tgactaattc tactagtcta taatctgagt
    11461 ttccgctact ttcttgtacc agtgagctga tttcttagga taacgttctt gagtttcaaa
    11521 atctacgtag aagagaccat aacgtttctc ataaccgttt gaccatgaga agacatccat
    11581 taatgaccaa atgaagtaac cttttacatt agctccatct gcaatcgcat cagacaagat
    11641 ctccaagtgt tgtttcacgt aatcaatacg accatcatcg taaacagtgt tatcaacgaa
    11701 ctcatcttta tagccgagac cattttcagt gatgtaaatc ttcttgtagt taggataatc
    11761 tttcttcaca cgcatgattt ggtcatacaa accttgaggg tagataatcc aatcccaatc
    11821 cgtgcgtggt acatagtcag gagctacacg acgaccaaca cctttgattt gatacttaga
    11881 gcttcctttt tcacctttac cattatggat aatttcagtt tctccatcaa aggcttccat
    11941 ccagtcactc atatagtagt tgattcctag gaaatcattc aagtcttttg cagcttctaa
    12001 tgctgtaaaa tcttcttcac gaagatccaa actaccacca ttgactgata agatatggtt
    12061 gacaccttcc atggtttcag ctgaatagcg acctagataa gttgcgtcta agatgaattt
    12121 attgtggatg atatcttcca actcagctgc acgaacatct gctggatttt caggatctag
    12181 aggatattta gtaggcaggg cgtgaacaac accaatttcc cctttatagc ctttctcttt
    12241 gtacaatttt accgcgcgtg catgagacac catcatattg tggtgtgatt gaaagacttt
    12301 ggcaaggtcg tactggatac ctggagggaa tttcccaacc aaatattgac catcaccgat
    12361 tggtccaatt tcattaaagg ttgtccaata gtttacttct ggaaattctt caaaacagaa
    12421 ggcagcgtag tctacaaaat gttcgatatt ttcacggttt aagaagtctc catttgagtg
    12481 gagagcttct ggcgtgtcaa agtgatgaag agttacaaaa ggctcaacat gacgtttatg
    12541 acactctgca aataaattat gataaaactc aacaccttta gcatttactt ggccgtaacc
    12601 agtcgggaaa atacgtgacc aagcaataga aattcgaata ccattgacac catactcttc
    12661 tgctagcttg aggtcaactg gatatcgatt gtaaaaatca ctagctggtt cggcagtgta
    12721 ccagtagtta tcctcaagat atttatccca agcaactggt ccttttccat cagtatgtgt
    12781 agcaccttct gcttgataag cagctgttgc gccaccgaaa ataaagtctt ttggaagtgt
    12841 ttttgtcatt tttttcacct atttcttgat ttaaataaag taaaagtgag aggagaggag
    12901 tcagtgagcc atgcttctcc atctcacttc ttgtaccaag tcactgaatt gtgacatgag
    12961 gaggtaaaaa cgatatcttt ttaccgacga attaataagg cgattaggaa attcgccata
    13021 gcgatttccg taacgatggg agactgtttc acagttccta gccttaatcg aattgctctt
    13081 gtacgaatgc tagggcacct tttccatcac gagttaattt gatgtattga gcgccttctg
    13141 tcttagcaag tttaataccg agcttatctg tttctgcctt catatcttca aagtttgaag
    13201 caacttgagg agcaaggata accaaatcaa actctggcaa catttcacgg tgagcaccat
    13261 agccgcctgc tgctgctttc acagggacat tgtattctgc tgctgcctta ttcaaagcat
    13321 ttgcaaggag accacttgta cctccacctg cacagagaac gaggacattt gtttcttcag
    13381 tgatggtatt ttgtgctgca tcgacacccg ctttttcaag aatagcatcc gcttttgcag
    13441 tgttgaagtt tgcagcaact ttttctttca attcagatga agagtttcct ttccgttctt
    13501 cttctaaaat ttgatggtca taaactttaa caaatggata atagattaaa gtgtcgataa
    13561 tgattaaagt tatagccaag acgaatgaca atggagccag cgccgttccc ataacaatac
    13621 caattggagc aggtgttgtc caaggtaaaa taatactgaa actattcatt tgtagaacat
    13681 ctacaaaaaa tttcataatc caaacattga taataggagc agtaacaaac ggaataaaga
    13741 agataggatt taaaacaatt ggagcaccaa ataggattgg ttcatttacg ccaaagaaag
    13801 taggaactac agacgcacgt ccgacaattc tatttctttt tgatttacat aaccacataa
    13861 acataaatgg aactactagt gttgcaccag taccacccat tgttacaaca aaagtttgag
    13921 taactggatt taaaatttta tctgcgtgca taccagcttg cacaagctga acattagctt
    13981 ctatatttgc ataactgata gctacaatta aaggttctac aacagatggc ccatgaattc
    14041 caacaaacca aaagaaagca taagcaccaa atacaatagc taaaccgata taaccatcag
    14101 tagctgaaaa tagaggggct aatattttac caacagattc tgctacattt gtaccaaaaa
    14161 tatttctaac aattaaatcc aatccatata ttgaaagaac agataaggca aacggaataa
    14221 catctttaaa aacttgtgca atatttggtg gaacctcttc aggaagtcta atggttacat
    14281 tatttttaat acatacttta tagatattta ctgtaataaa agctgccaaa aatgcagtaa
    14341 gtaatcctct agtacctaaa agaccattag caaatccacc ttcaattgga tcagctgcca
    14401 gtattaacaa tccaacaaca gctgctaaaa aagttgacat gtagttgatt tggttggttt
    14461 tctccatact acgtgtatta actgaatctg ttaacgattt tgcagttgtc ccagctacta
    14521 agagagctaa aatccccatt gagtagttgt aaggtttcaa aataaaagct aactgttcat
    14581 cagaccattt aaacccaaaa atattgggca cagcagctat tagtataaaa atacttgaga
    14641 ataatactgc tggcatactg gaaataaaac catcttttat cgctcttaag tatatatttc
    14701 tcgataattt ctcaaagaaa ggctttcctt tctcaataaa aattattaac ttatccattt
    14761 tatttaactc ctctcttgta aagttcaatt aaatggtgca ttaggtcttt taacaagata
    14821 gttgtcatca agtgatcttg accatgcatc atggtcacac tatacgctaa gtcctcacca
    14881 gaagcttcct tagtcaatag acttgtttgc gcgtggtgag cctctgcaat acagctacca
    14941 gcttcctcta ccagagcgtc cgctttttca aaatcaccag cttcagcagc cttcaaggct
    15001 tccaatagtt ttgaacgagc atcgccagca taggctacga tttcaaaacc taacaatgtt
    15061 acttcttctc tattcatgat agaattctcc ttatatagtt ttaaataaat ttttatgaca
    15121 ataaacgttg gatatgtaga actagataaa ctcgttcact tttatacaaa tcaagacccg
    15181 tatgttgcgt aatcacatca tagatcttgg aaccaatctc gaaggctttt ggataggatt
    15241 gtttaatatg atcttccata tccagaagtg attggttatc atctctagat ctgtctaaat
    15301 aatccaagaa ataattcaaa tggatcataa agcgatcata gaaatggtta ttctttttag
    15361 ttcgttgaat tgcatagtcc gttaaaactt cttcaacatt cctgagaatt tctttcctct
    15421 tatcaatcga ctccacaagt tccacttcat tttcaccttc agcattaatg aaatgataag
    15481 caatccgaat aatttcgtcc tcaggaaaat gatctgctag cttctgacgg taaatttcaa
    15541 aagcttcatt tgcgatttga aaagcgacag gatacttagc ggaaatatct ggcagattac
    15601 tatccttgta ccttccttga gttagagctt gataagaaca gtaaatatga tctgtcaagg
    15661 ttacatagag atactcttga atcggataat gatatttctt tgatagctta tcaatgattt
    15721 cataggtcac tgtgataaaa tcaagcggaa catctttgag aagagccata aagttttctc
    15781 tggactcttc ggtcttcatc cgaaagattt tctcaacctg attttcagca atcaaatccc
    15841 ccttcttctt tccgaatgca attcccttac caattacaat cacctcttct cccttatcat
    15901 ttctgacaag cgagacattg tgattcattg gatttagaat tcgatacatg tcaacctcct
    15961 tttatatctt aaaggtatat aagtacaaaa aatgaccaca aatgaactag aaaatcagct
    16021 gatttctaat tcacctgtga tcatgcctaa tattacttag taacactcac cttgtattaa
    16081 cttgtgattt aagtatagca caagtaagtt attttgtaaa cctttacata caactttttt
    16141 taaatttttt tagattcatg ttcctaaact aggaggactt tcttacacac gttctttcca
    16201 tgaagtcgct gttgtttgaa gaactttatt gagctcatca atgttttcaa atccagttgt
    16261 gcgaagccat tcgcgagctg ctgcttcacc atctttgatg taagcttcaa ctgatcctgc
    16321 ccatgtagca cggccacaaa gaactccgtt aaagtttgca cctgattcat gagcaaatac
    16381 aagagtatct tggaagagtt tagctgatac accagcactc aagtagatgt atggcaagtt
    16441 cgttgcttca tcttgcgctt tgaagaaggc tgctgcttct tcacgtgtat aaactacttc
    16501 accttcagcg aagccttcaa catatttaat gttaacagga acttcaactt tcaagacatc
    16561 aatgttaaag cgtgggtctg aaaagacttt catagcgccg ataactttgt gtggttttac
    16621 tttcgcgtat tctacagaac ctgcatccgc aattttttca tcgtaagcaa ggatttcaag
    16681 gaagaatggg atatcttcag ccacacactc agaaccgatg cgttcgatgt aggcttgttt
    16741 ttcttgattg agttcgtctg agctatctac atcatagtaa agcaagaatt taactgcatc
    16801 tgcaccttct tctttaatac gttttgcaga ccagacatcc aagcagtctg gcaagcgttt
    16861 tgtgcttgtt gtgtcataac ctgttttttc ataagcaagg agaagaccag ctttttcatc
    16921 aagagcttta gttgctggaa gtccatactc agggtcaaga agcatagatg aagcgtattt
    16981 agtcaattca tctgctacca agactttaag ttcttccatt tgggccacag ttggttcttc
    17041 tgtttggtgt tgagccatga ggcgtttcaa agcaccacgt tggtcaaatg caagagctga
    17101 gatgatacca ttttcatcag aaagtttttc taagcgtaca cgtttttgtt ctgttaaagc
    17161 cattttatac ctcttttact attaattgat catatagaac ttgatagttg gccatgttga
    17221 catgaccagt cattttttct tgagcattga gcataccaag gacatttgcc ttgatgagta
    17281 attctgcatc cgattctttg tgaagaagtc ctgaagaaat tcctgccaca gtagagtctc
    17341 cagatccaac aggatttacc acctgaattc taggaatatc taccttgtag aaagtgtcac
    17401 catgtttggc aaaagtaccg ttggcaccaa gtgaaacgat aatccattca atccctgcaa
    17461 acaaagggtc ttgaagtact tcttttaatt catccaaatc ctcagaaact tctcttccaa
    17521 gaagctgaga caattcttca ttatttggtt tgatgactgt tggtttatgg ggtgattcaa
    17581 gaacagcctg aagtgctgca cctgagcagt ccaagactac aggcttgcca gcttgattag
    17641 caagttctac caagctcgca tagtaatcaa ctggaaggcc agctggcaga ctacctgaga
    17701 tggccactac ttcaactgat tccaagagtt ttttgaaatg ttccaaaaac tcttgacctt
    17761 cctgttccaa tacttcagga cctttttcaa gaacttctgt ttggttgtct ccgtggagaa
    17821 tagcgataca gttacgagtt tctccctgaa ttgagaagaa atctttcttt acttgattat
    17881 cgatatgttc aaccaaaaac tcaccaagtt tgccacccac taaaccagta gcaagaacag
    17941 aatcaccaaa ttctgaaagt actcgggtaa cattgagtcc cttaccacca gccgttttgg
    18001 ttacatccac cacacgattg acagtatcaa tcttcaactc atccaaggga taggaaatat
    18061 caatggatgg gttcattgta actgttaaaa tcataggtta cctcttagtc gtggtattct
    18121 ccgcgatccc atttttcaag gaattcagtg aagaagtttg cgtctgtttg ttgagcattg
    18181 tgactttcat ggtgttcaat tttcgcaatc aattttttgt tttcttcaga tggtttgtat
    18241 tcagcatgaa tgaaagcttc gatgatatca cacataagca attcaccagt aatcttacca
    18301 ccaaaaccga taacgttggc gttcaattgt tctttagcat aaagggctgt tgtcatatca
    18361 cgaaccaagg cagaacgaac acctggaact ttatttacag cgttgttgat accaacacca
    18421 gtaccacaga tacatacccc gagatcagct tgaccactag ttactgcttc ccctactttt
    18481 ttaccaaaga ttgggtagtg agtccgtgta tggtcatagg taccaaagtc aatgacttca
    18541 tatccttttg atttcaaaaa ttctgaaacc gccatttttt catcagttac gatgtggtca
    18601 catccaattg caattctcat ttttaactta cctttcttac tgtaatctaa ttagcccatt
    18661 ttgttcaaca tgtcaacccg gatttgatga cgtccaccgt cgtatttacc attaacaaat
    18721 cctttagcga tgtttttagc caattcatca ccaacaagtt gtgcccccat agtgatcata
    18781 cgtgagttgt tgtggccacg agtcatataa gctgaacgtt cgtcagatac ttctgcagca
    18841 accattcctt tgatcttagt tgcaaccata aatggaccag ctccataagc atcaatcacg
    18901 ataccaaggt tttgttcttc tttgtttact tctgcagcaa cagcgagagt cacatcaaca
    18961 aagtcttgac cttcagctgt aacatccaca aggtggaagt tttctttttc taagaagtct
    19021 ttcacaactt ctttcaatct caaacctgca gcatctgcac cgataacaat agacatattg
    19081 tatactcctt tttatttttt ctatgctgga ttccagcagt gtattggctg tctttaaaaa
    19141 acagtcaatt agtcctcaca aacataatat actactattg tttgaagaag tcaatagttt
    19201 gtgtttgttt ttgttattta ttttttactt ttttataaaa cttctatctc aaaccctaat
    19261 tcttcaacct gattggcttc taagagacaa acattcttct tatcttctaa atgatctcct
    19321 tcttcaagga atgttgacaa gccagaccat ggttcaaagg taatgaaagg tcccttgttc
    19381 aaagttgacc agatgatgag gtttggaaat tctgcaaaat gcactttcaa tcccttatca
    19441 tgtttaagag aacgaagggc aattgttcga gattgcaatt catccaaagt cactgcatct
    19501 gtgctgaaaa gatcataact aagatctatt tctttttgtc cctctagcca tggacttcta
    19561 tcttggaaat ccaacatacc tgtttctggg aaaggacgtg gaacagagca agtctcttct
    19621 ttctcagact ctagataata atcttcatag actccatcat caagtagagg acaattaaat
    19681 cctggatgtc caccaataaa gtaaggcatg accttgctag tttctttatt agacttcctg
    19741 caaaactaga atcctagttc atgattgata ataccagcac tcaaattcat tcgtaatccg
    19801 aagcgtttac gatgatttcg ataggttgtt gaaaacattt taaacgtttt tactttggca
    19861 aagatgttct caaccttgct tctctcctta gatagcgcat ggttataggc tttatcttca
    19921 gctattagcg acttgagttt gctggattta cgtgg
//
LOCUS       DBERDS010000036        19918 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.036, whole genome shotgun sequence.
ACCESSION   DBERDS010000036 DBERDS010000000
VERSION     DBERDS010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.036"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(156..431)
                     /locus_tag="ACL73E_001454"
     CDS             complement(156..431)
                     /locus_tag="ACL73E_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGS0801411.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(537..1376)
                     /locus_tag="ACL73E_001455"
     CDS             complement(537..1376)
                     /locus_tag="ACL73E_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGS0801412.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1518..2366
                     /locus_tag="ACL73E_001456"
     CDS             1518..2366
                     /locus_tag="ACL73E_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGS0801413.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2459..3376)
                     /locus_tag="ACL73E_001457"
     CDS             complement(2459..3376)
                     /locus_tag="ACL73E_001457"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGS0801414.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWY"
     gene            3853..4002
                     /locus_tag="ACL73E_001458"
                     /pseudo
     CDS             3853..4002
                     /locus_tag="ACL73E_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4328..4621)
                     /gene="rpmA"
                     /locus_tag="ACL73E_001459"
     CDS             complement(4328..4621)
                     /gene="rpmA"
                     /locus_tag="ACL73E_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGS0801415.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4638..4982)
                     /locus_tag="ACL73E_001460"
     CDS             complement(4638..4982)
                     /locus_tag="ACL73E_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGS0801416.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4998..5312)
                     /gene="rplU"
                     /locus_tag="ACL73E_001461"
     CDS             complement(4998..5312)
                     /gene="rplU"
                     /locus_tag="ACL73E_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGS0801417.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQEVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5349..5436)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5531..6130)
                     /locus_tag="ACL73E_001462"
     CDS             complement(5531..6130)
                     /locus_tag="ACL73E_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGS0801418.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6601..6843
                     /locus_tag="ACL73E_001463"
     CDS             6601..6843
                     /locus_tag="ACL73E_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGS0801419.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALE"
     gene            7120..8133
                     /locus_tag="ACL73E_001464"
                     /pseudo
     CDS             7120..8133
                     /locus_tag="ACL73E_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8449..9423)
                     /gene="pta"
                     /locus_tag="ACL73E_001465"
     CDS             complement(8449..9423)
                     /gene="pta"
                     /locus_tag="ACL73E_001465"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGS0801420.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(9467..10363)
                     /locus_tag="ACL73E_001466"
     CDS             complement(9467..10363)
                     /locus_tag="ACL73E_001466"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0801421.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSYIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(10360..11178)
                     /locus_tag="ACL73E_001467"
     CDS             complement(10360..11178)
                     /locus_tag="ACL73E_001467"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGS0801422.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(11162..11833)
                     /locus_tag="ACL73E_001468"
     CDS             complement(11162..11833)
                     /locus_tag="ACL73E_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGS0801423.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRSITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            11961..12530
                     /locus_tag="ACL73E_001469"
     CDS             11961..12530
                     /locus_tag="ACL73E_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGS0801424.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTLDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            12643..13602
                     /locus_tag="ACL73E_001470"
     CDS             12643..13602
                     /locus_tag="ACL73E_001470"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGS0801425.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            13612..14727
                     /locus_tag="ACL73E_001471"
     CDS             13612..14727
                     /locus_tag="ACL73E_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGS0801426.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMH
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            14732..15079
                     /locus_tag="ACL73E_001472"
     CDS             14732..15079
                     /locus_tag="ACL73E_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGS0801427.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            15087..15302
                     /locus_tag="ACL73E_001473"
     CDS             15087..15302
                     /locus_tag="ACL73E_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGS0801428.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            15385..16026
                     /locus_tag="ACL73E_001474"
     CDS             15385..16026
                     /locus_tag="ACL73E_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGS0801429.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            16044..16733
                     /locus_tag="ACL73E_001475"
     CDS             16044..16733
                     /locus_tag="ACL73E_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS0801430.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGKPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(16730..17410)
                     /gene="radC"
                     /locus_tag="ACL73E_001476"
     CDS             complement(16730..17410)
                     /gene="radC"
                     /locus_tag="ACL73E_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGS0801431.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHLSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(17453..19744)
                     /gene="pcrA"
                     /locus_tag="ACL73E_001477"
     CDS             complement(17453..19744)
                     /gene="pcrA"
                     /locus_tag="ACL73E_001477"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGS0801432.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSVLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
BASE COUNT         6159 a         4191 c         3585 g         5983 t
ORIGIN      
        1 ttagcaattg tttcgtacta ttttagattc agtctactat atacaatatt ttcggaacat
       61 tcaacttttt aactctattt attactagat ttcataatta aaaagcctac tgaccaagct
      121 agaaagcttg atacaatagg ctttttaaag actgattatt taacagcgtc tttaagagct
      181 ttaccagctt tgaatgctgg tactttagaa gctgcaattg tcatttcttt accagtttgt
      241 gggttgcgac ctttacgttc tgcgcgctca cgaacttcaa agttaccaaa accgatcaat
      301 tgaacttttt caccagctgc aagatagtca gctactgctg caaatacagc ttcaactgct
      361 gctgctgagt ctttcttagt caattctgta gcttctgcta ctttagcgat caaatcttgt
      421 ttgtttgcca tgttaatgat tcctccaaat aatttctaat taacaaatat aatcatatcc
      481 taaaatccct tttaggtcaa gttaaaaacg ctatttcttc ccattttatt tattttttag
      541 gagtggtaac gtatcaaaat agcccaagcg ttctcacccg tgtgagtttg aataatggaa
      601 cccgtttcca aaacagaaat tggcttttca acataagctt gtaagctttc tttcatctct
      661 tttgcccaat catcactacc agaatatgaa attccaatct ctgctacagc acgttcagaa
      721 agcgatgtta tcaactcatc taaccatttt ttaaatgttt tagttccacg acctttaacc
      781 attggctgca attcatggtc tttcatttgc atgacaacac ggatattgag aagggagctc
      841 aacaagccag ttacacggcc aattcgtcca cctttgacaa gattttccaa agttgaaaca
      901 ccaatataaa gctctgtatg gtttttaacc tcttctacat gagataaaat tgcctccata
      961 tctttacctt cttgagctaa cttcgcagcc tcaacaactt ggaatttcag ggcttggtca
     1021 gtgaaggaac tatcaacaac agtcacatct gcagtagata ggctagcacc ttggcgtgct
     1081 gcttctaccg tacccgaaag agcatgggac atatgaatag caagaatctg gccaccatct
     1141 ttgcataggt cttcaaaaat ctcagcaaag acacctacag gtggctgact tgttttcgga
     1201 agattcttac tttcttgcat caactgaaga aatttacctt cttctttcaa atccgcatca
     1261 gaataaacaa cattatcaat cattacagat aatggaacaa ttgtaatatc taattgcttt
     1321 actagttcag gttcaatagt aacagatgaa tcggttacaa tcttaatttt tgtcatagta
     1381 tcaatctttc tattttagga ttcagattgg tttccttact tctaattata tcaaaaaaaa
     1441 gattaaaaat cctaatggag tcaatcaaat tttccgtaaa atttgatata atcaacttat
     1501 aagaaaagag gtgtcctatg attaaaaaaa tttaccccat ttttaccatt ttactaggtg
     1561 ctgctattta tgcttttgga ctgacttatt ttgtagttcc ccatcatctc tttgaaggag
     1621 gggcgacagg cattaccctc atcacctttt atctttttaa aatccctgtt tccctcatga
     1681 acctgctgat taatattccc cttttcatcc tagcttggaa gatctttgga gccaaatccc
     1741 tctattctag tttactagga accttagctt tgtccgcctg gttagctttt tttgagcata
     1801 ttccccttca tattgatctt caaggtgatt tactaatcac agcccttata gcgggaatcc
     1861 tattgggaat tggccttgga attattttta atgctggagg tacaactggc ggaactgata
     1921 ttctagctcg tattctcaac aaatacactc atatatccat aggaaaactg ctctttatct
     1981 tagatttttg tattctcatg ttgattctcc taatcttcaa ggatttgaga ttggtttcct
     2041 acacgctttt gtttgatttt attgtttctc gtgttattga tttgattggt gaaggaggat
     2101 atgccggcaa aggctttatg attatcacaa aacgtcctga ccaacttgct aaggcgatta
     2161 atgatgacct cggaagaggt gttactttta tttctggtca aggctactat agtaaagaaa
     2221 atttgaaaat catctactgt attgtcggaa gaaatgaaat tgtgaaaacg aaggaaatga
     2281 ttcatcgaat cgatcctcaa gcctttataa ctattacaga agcccatgaa atcctaggag
     2341 aaggcttcac ctttgaaaaa gaataaaaag aggtaatgtc gtgacctcaa aagttagact
     2401 aaatcatcta tcttttgggt tacagacaac ctctttttta ttttatttac tcaagctctt
     2461 aataccaatt ccgagttact tcttcatcag cctttaactg atccactaat tggtcaactg
     2521 agtcaaattt ggtcatatct cgaatgcgat caagccaata aaccatgacg gtttccccat
     2581 aaatatcttg attaaaatca aaaatattga cttcaaaacg tgcttcttct ccatcaaagg
     2641 tcacattttt cccgacacta gccatagcac gatacttctg tctctgaatc tcaacatcaa
     2701 caacataaac gccatctgct ggcatataag tacggtctaa aagcactaaa ttcgctgtcg
     2761 gataaccaat tgtacgacca cgagcattac catgaaccac catacctctt gatggaagcg
     2821 gtgcccccaa aagttttcct gcttctttca catttccatc taaaatagct tgacggatac
     2881 gagttgaact aatctttcct ttctcatctt ctacaggtgg aacaatgata acttctccat
     2941 caaagtaatc ctttaaatct tctgctgttt ttttgtcaga accaaatgta taatcaaaac
     3001 ctgcaacaat aattttggca ttcatagcct tgatataagt tgcaaagaat tcttgtgcag
     3061 tgagactagc gaattgacta ctaaaatcaa ggagatataa ttcttctaca ccttcgcgct
     3121 ttaattttct ttcacgttca gcagggttca aaatatgcaa aaacaaatct ggatgataag
     3181 gctctaaagc gatctttgga gattcattaa aggtcataac gacgataggc aacaaatcct
     3241 ttctcgcagc cttgttggca acacgaaata attcttgatg ccccttatgt atgccatcaa
     3301 aatagccgag aacaacgact gaatcagatg gtgtgccaat atctttttgg ttttttatag
     3361 gaatagtaat aatcataaaa taattatatc atagcgatag ctatttctgg aacagaaaat
     3421 ctgaaatgtt gtttttttca catgaagtgt acctgttttc aaaaagcact ttattctatc
     3481 gttgcttaac tatgaacttt gcaatattct tctcaaaaac ttgtaggaca tcttcaaaat
     3541 tttgcaagga gtgattagac ttgttcggta accataaagt gtcatactat gcttatgtat
     3601 gaaaaagcaa tgcaactaac tcctgagaac tttaaattac taattggtgc cgaaaaggta
     3661 gaatttagaa tcgaggtaca cctatggctg taaaatttac aaaatgagac aacttgggca
     3721 agatgtttga agaatttcct aaactccctg atttgaagca agtcactttc cctgatgaca
     3781 aaaaaagcca aagcagtaaa gaaaaactag atgactgctt tccaacaact tccatctagt
     3841 gtgcttcaga ctgggctatt tttctctcca tctgttagct tggattctca gaccgtttca
     3901 gctaaagaat atcttttccc ttatcagaag gaacgggctc aaaccactca gacaagtgaa
     3961 gggacgacaa gccaatattt gaaaccagat agcagttttt atagtcaatt gaaataaaat
     4021 ctgaagaaat cgagtaggaa actcatatca atttttaaca gtgttctatt ccagattcat
     4081 actcaatgaa aattaaagtg caaactagga agttagccgc aggctgtact tgagtacggc
     4141 aaggtgaaac tgacgtggtt tgaatttgat tttcgaagag tatcaatcca ctatacatat
     4201 taaaaagtat gggtatcaaa acaaaaaaac aggctctccg aaaactcgga aagccttatt
     4261 ttaagctgtt tctagcttcc tcacctttac atttcaaggt tcgggataaa aggttcaatg
     4321 gaccttttta tttagcgatt gggtaaacag aaacttgttt tttatcgcgt cctttacgtt
     4381 caaagcgtac tacgccttca actttagcga acaaagtatc gtctccacca cgaccaacgt
     4441 ttacacctgg atagatgtgt gtaccacgtt gacggtaaag gattgatcca cctgttacag
     4501 tttgtccgtc agctgcttta gctccaagac gtttcgcttg tgaatcacgt ccgtttgatg
     4561 tagaacctcc accttttttg tgggcgaaaa gttgcaagtt gttaagagtc atttttaaca
     4621 taatgttttc ctccgtgtta gttttctgtg ataactctgg tttggacgaa ctcagaagag
     4681 ttctccgata agtttgccat acctaagaaa aatgattcaa agaataactg ggtcatttct
     4741 ctctggtgtg aaggaagatc ttttggtatt tcaaccatca gatagccacc ttcatcttcg
     4801 tttaattcta ggattggttc atagcctgca aatttctcaa tagaattgat aaagttaatg
     4861 gcaagcgtag aaaccgatgc acacacgaca tctaagccgt attcgccact ctcggcgtgt
     4921 ccagtaattt ccgcactcct cagctcgcca tcttcggctc tctcaaagac tgcttgtatc
     4981 atgtgttctc cttaaaatta agcgttaatt gcgttgatga caacttttgt atatggttga
     5041 cggtgacctt gtttacggtg gctacctttt ttaggtttgt acttgtaagt aacaactttc
     5101 ttttgttttc cttgtttttc aacagttcca actacagtag ctccagcaac aagtggagtt
     5161 ccgacaacag tgttttcacc accaacaaga acaacttcgt taaaagtaac ttcttgacca
     5221 gcttcaacgt tcaatttttc aatgtaaact tcttgaccaa cttcaacttt aacttgtttt
     5281 ccgccagttt tgataattgc gtatgtgctc attatgcacc tcctatgatt tttatgggtt
     5341 tccccgattt ttttgtgaag actcgcctag catcgtggga caaaccactt aaacttgaat
     5401 aatcaagcaa cgatgttcgt gcggttgcac aggatcgtgc atagtcaact cttcaagtgt
     5461 agcatatttc ctattttctt acaagtaata acacctaaaa tcaagctttt tcttttactt
     5521 ttttctgcca ctaggcaaaa agcatactga gataaaaaat gctcatcata ataggaacac
     5581 caagaatggt cttttcatga tagaaaatcg tcaaatagac tgaaaagaca acgccaagga
     5641 caaaactact aagcaggcta acaaatatga acccttcacg caaaaaagga gtgtgcttag
     5701 ttcggaaata atctccaaaa gctagcattg ttcgtttgat attccctgtc ataaaggcat
     5761 tattgtaggc aatacccgaa acctcaccaa aagcagttgt caccagtccc atacagaagg
     5821 ccaagggcgg cactagatag atattatcta cagtttgtgg cacaaaacca ataattattg
     5881 ataggattgc taaaggaatc aaggacagaa tagatttttt cacaattctc aatttttcct
     5941 tataaatcgt taataaaaag actcccatca taaacgctat taaggttaaa agcttatccc
     6001 taatatccga aacattattt tgtatgagct ctaccgaaag aaagacaaca tttccagctt
     6061 gtccagctac aagggtattc ccgcgaacaa taaaagtgta agcatccaca tatccagcac
     6121 aaaacgtcaa aaaagtgcta accttttaga ctgacgtgat atttttctta taggtaataa
     6181 cctcattttc cctcccattg tattttctct tagaaatatt gtaccatttt ctttctaaaa
     6241 aatcgtaggc taccatttag attttactat tagcataaaa ataataatag acaactattt
     6301 atccaaaaat agatagaggt aacatgtttg caaacaaagc atacgaacct ttagtaaaat
     6361 catttccatg aaactagaat agagcccctc ttagcaaaaa tcattatttt aatttatttc
     6421 taatcactcc ttgacataaa taactctcac caataaaaga ctatgtctta aaaaaatggt
     6481 ataataaaat caatacttgg acttgatggc tatgctacta ataacaatta ggagagaaaa
     6541 tcaggcactt gttaacaaca aggattatcc ccttgagatg aaaggaactt tagaaatctt
     6601 atgatgaaca tgcaaaacat gatgcgtcaa gcacaaaaac ttcaaaaaca aatggaacaa
     6661 agccaagctg aacttgctgc tatgcaattt gttggcaaat ctgctcaaga tcttgtccaa
     6721 gcaaccttaa ctggcgataa gaaagttgtc agcattgatt tcaatccagc tgtcgttgac
     6781 ccagaagacc ttgagactct ttctgatatg accgttcaag ccatcaactc tgctcttgaa
     6841 taaatcgatg aaactactaa gaaaaaactg ggtgctttcg ctgggaaatt gccattctaa
     6901 aaacaaggag ctagaacaat gcttgtcgat aacaaaggct aagaaaggtg caaaaattat
     6961 aaaaaacgca tagtatcaag caacctaaaa ctttgggctc tataatattt gtagtgggta
     7021 aatcccctat ggatattacg gagcctattt ttgtgtagaa aaaaagtccc atatgaccta
     7081 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
     7141 acaaaattac tagacattaa agaccctaat atccagattt tagacatcat caataaggat
     7201 acacacaagg aaatcatcgc caaactggac tatgaagctc catcttgtcc tgagtgcgga
     7261 aaccaattga agaaatatga ctttcaaaaa ccttctaaaa ttccttatct tgaaacgact
     7321 ggtatgccta ctagaattct ccttagaaag cgtcatttca agtgctatca ctgttctaaa
     7381 atgatggtcg ctgagacttc tatcgtcaag aagaatcatc aaattccttg tatcatcaac
     7441 caaaagattg atcagaagct aattgaaaag acttctatga ccgacattga tcatcagttg
     7501 tctatttcaa cttcaactgt cattcgcaag atcaatgatt ttcactttga gcatgatttt
     7561 tcgcgtcttc ctgagattat gtcctaggac gttgaaacag tctggggagt gactgtttca
     7621 atcgggagat agagatgagc tttattgctc aggactttga taagctcaat atcataactg
     7681 ttcttgagag cagaacacaa gccatcatcc gaaatcccat gaatacaagg ctatcaagcg
     7741 atactgaaag ctcattcaac aagatagtca gaaactgagt gataaacgat tttatcgccc
     7801 tacttttcgt atgcacttga ctaataaaga aattctagat aaacttttga gctattccga
     7861 agacttgaaa caccactata atctctatca gctcttgctt ttccacctct ttttcagact
     7921 ctgtttaaaa ccttcctcaa agataaagag aaaatcgtca acgcccttca attaccttat
     7981 tccaacgcca aactggaagc caccaataat ctcatcaaac ttatcaagca caatgccttt
     8041 ggttttcgaa actttgaaaa cttcaaaaaa cggattttta tcgctctgaa catcaaaaaa
     8101 gaaaggacaa aatttgtcct ttctcgagct tagcttttct tcaacccact acagttgaca
     8161 aagagccaga aaacgcataa tagcaggtgt caagacactt aatattatgc gttttctcat
     8221 gaaaaaattc tcttttcata ctcatttaaa atcaaaaagg gaatttatcg ttttacggac
     8281 atgtatatta cagatttcta taggtcgtgt atagacagga tatcatcgct tggaagtttt
     8341 cctttttgac accaatcagt aatttagttc tcaggaatta atggcagtgc ttttcgtaca
     8401 tagtttcata actacagtat agcatagtat atcgctttat agttttcact attgatgaac
     8461 tgcttgagct gctgtgatga gggtcaactt gtaaacatca tctgcattac atccacgaga
     8521 aagatcatta actggcttgt ttaaaccttg caaaacaggt cctacagccg caaagccacc
     8581 caggcgttca gccatcttgt aaccgatatt tcctgcctcg atacctggga agatgaagac
     8641 atttgcttga ccagctaccg tacttccagg agctttcaga gctgcagttt caggaacaaa
     8701 ggctgcatca aattgcaact caccatcgat ttcaaggtca ggacgcaagt cgtgagcaat
     8761 tttagttgct tcaacgacct tatcaacgct ttcaccaaac cctgaacctt tagtagaata
     8821 gctcaacatg gcaattttag gttcgatgcc aaacatctta gctgtgattg ctgagttgat
     8881 ggcaatttca gccaaggctt ctgcatctgg attgatgtta atggcacagt ctccaaatag
     8941 gtaacgttcc gtaccacgaa ccatgaggaa ggctcctgaa gtacgagtta catttggacg
     9001 agttttgatg atttgtagag ctggacgaac tgttgaagct gttgagtgaa tcgctcctga
     9061 caccattcca tcaaccaagc ccaagtaaac caacatcaca ccaaagtagt tgacatcttc
     9121 aaccaaaacc ttgcgtacat cttcttcagt cattttgccc ttgcgacgct ccaccaaggc
     9181 agaaaccatt tcttcaaatt gaggataatg ttgagggtcg atgacctcat aaccatccat
     9241 gattccttca atttcaagat aaattttaat tttttcagga tttccaagca aaacaggaat
     9301 cacttctgtt tcttttacta agcgttttgt tgcttgaaga atacgaggct cttccccttc
     9361 agggagaacg atacgagcat ttttaccaac aaggttggct ttgagacttt caaaaacttc
     9421 catgagtttt ctcctttaag ataataatta tactctgaga cagtttttat agagtattag
     9481 ttgataactg ggtaataagg ttactgaaat catccggcaa gggactttct aactgcaagt
     9541 cttgctctaa aaatggatga taaaaggata ggtaatggca atgcagagcc tgacgttgaa
     9601 taccatcttc cagactacca ccatacaaat catctcccag caaaggaaaa ccgatataag
     9661 aaaaatggac tcggatttga tgggttcgac cagtgtgcag gtgaatatag accaagtgaa
     9721 tatttccata agaagctaca atcttgtatg aagtatgggc atactttccg cctttagcca
     9781 ctcgtctggt aataatggaa tcttcatcac gcgcaatcgg agcaataatt tccccttctg
     9841 gctccaaatg tccatctccc ttaaccaaag caaagtagcg tttctcgata gatttcttct
     9901 gcaactgctt gtctaatcgt gcatgggcat aaccgtgctt ggcaaagagc atcaagccag
     9961 aagtgtccct atctagtctg gtaacaatgt gaacctgctg attttcataa ttttgcttga
    10021 catagtaacc cttgataaaa ttggcaatgg tattagagtg attgacacta ggaatagaag
    10081 ccactccata gggtttattc aagactagaa agtggtcatc ctcatagaga atatctaatg
    10141 gatgctcaat agcctccaag gtttcaaagc cttcctcagc gggaatgtaa atggtaacgt
    10201 agtctccaac gtccaataga tacgttgcat tttgcggttg attattgacc agaatcgctc
    10261 cacctcgaaa cttaatctta gccagcaatc ccttagaaac ctcgtgcttt tttaaaaagg
    10321 tcttaacctt gacatgttca tctgcgataa attcaaacct cattcatcca cctcaccgat
    10381 aaaggcatcc ttaacacggt tccagaaact ggtatggcta ggagtcgcga caaagtgaat
    10441 cttatgatgg tcgatttgat actcaatacg ctcaatatta cggaaagaat aaacgctatt
    10501 gtcaaccgaa atagtatgat aatcgtttct tgttggaata agttcaatct tatccttctt
    10561 aggcacaata atggaagagc ccagtgttcg ataaacacga ttattaaggc tggcaatttc
    10621 cgttaattgc aaagcttcaa tggtagggtg taaaacagca ccgccaagag acttgttata
    10681 ggcagtacta ccagtcggtg tcgaaactgt tagcccgtct ccacgaaaac gttcaaaggg
    10741 aacaccattt attacaatat ctgccaccat ggttcgatca gacctgcgga tgctggcttc
    10801 gttgagtgct ctgaaaatct taacttcacc attttcaaga aagaccttca cattcagaac
    10861 agggtaagaa acccttgccc cagtatctag ctgcaaatta gtcactagct tgtccaactc
    10921 aaaatcacga taatctgtat agaagcccaa atgtccagta tgaagaccga taaagcggac
    10981 cttgtcaagc tgattttcgt acttatgaaa ggccgacaag agcataccat ccccgccaat
    11041 ggaaatgaca atatccggat tggtatcatt gagtataaac tgatttctct tcaaacgatc
    11101 tcgcaattca tacaaaaccc tttgactctg cggttttcta ttggctatca gatcaattcg
    11161 tttacctgta ttcttcatct gtatcgtcac tgtttcctac accgtcattt aattttctac
    11221 tcaaaggatc aaaaagtgcc tgggcttctt ggatatcatc acgaatttca cccatttctt
    11281 catccaactg atgggcgatt ctagctgtaa tttccagtcg cttcttaatc tcatctggga
    11341 aatccccttg gtacttgtag ttgagagaat gttctatcgt tgcccagaaa ttcatggcca
    11401 aagtacgaat ttgaatttct gccaaaatag tcttagctcc attgatggta tcaaccgtat
    11461 attctactac cacatgatag gaacgatagc ctgatgcttt tctatgagta atgtaatctc
    11521 gctcctgtat gattcgcata tcctgacgct tgtgcaaaat atccactact tccttgacgt
    11581 catctacaaa ctgaaccatc acacgtaagc cagcaatatc ctgcaaatcg tgttccaagg
    11641 tcgcataagt aatgctacga cgagccattt tttctttgat gctctcaatt ggcttgactc
    11701 gaccggtcac aaactcaatt ggagaatgct tattttgctt acgatattgc ttacgaatac
    11761 cacgaagttt aatctttaac tcaccaacag cttgaatgta aggatctaga aattcttccc
    11821 attctaaggt catatattct cccttgttct catattatcc gtcaaaaata tctttgattt
    11881 tttctccaga ttcatataca ataaatacaa tgcttattat accataaatc cgctttcaac
    11941 gataaaaaaa ggtaagaaaa atgaaacatt tagaaattga attgaaaaca ctattgaaaa
    12001 aagatgaata caatcgtcta aaagaccagt tcacaggtgt cactcctgtt cttcaaacaa
    12061 attactacat cgacacgctt gattttgaac tgcgagaaaa gaaagtcgct atgcgcattc
    12121 gaacctttga agactgggct gagttgacac tcaaagtccc gcagagtgtt ggaaacatgg
    12181 aatacaacca aaaattgcaa ctaaaagatg ctgagaacta tctgagtaag gaagaacttc
    12241 ctcaagggct agtactggat gaattggcga aacatggtat ccaaagtaag aactggcagg
    12301 ttcttggttg tctaacaacg cttcgctatg aaatgaaaac agctattggt ctcatggcac
    12361 tggatcagag ccgatacttt gatatgacag attacgaatt ggagcttgaa gtggaaaatc
    12421 atgagcaagg caaacaggat ttccgacaat ttttagagaa aaatcagatt tcctaccaaa
    12481 aagctccttc aaaattggtt cgatttgtca aaagtatgaa aaatagctga aataatctcc
    12541 attttttggt aaaatagaaa agataaaaat acacaaatcc cagttcatat atgtaaggta
    12601 aatataacta ggatttataa agtttacaga ggacggtcta taatgtcaga tagaaaaaac
    12661 atgaaacttt tcgcactcaa ctctaaccaa gagattgcac aaaaaattgc ccaagctgtt
    12721 ggtgtcccac ttggaaaact atcatcacgt caattttcag acggagaaat ccaagtaaat
    12781 atcgaagaaa gtgtccgtgg ttatgatgtt tacatcatcc aatcaacaag tttccctgtc
    12841 aacaaccacc taatggaatt gttaatcatg gtcgatgctt gtgtgcgtgc aagtgcccac
    12901 agtatcaacg ttgtccttcc atattttggc tatgcacgtc aagaccgcat tgcttgtcct
    12961 cgtgagccac ttacagcaaa actagttgcc aatatgctgg ttaaggctgg agttgatcgt
    13021 atcctgactc ttgatttgca tgccgttcag gttcaaggtt tctttgatat tccagtggat
    13081 aatcttttca ctgttcccct attcgcaaaa cattactgcg ataaaggatt gcttggttca
    13141 gatgttgttg tcgttagccc taaaaattca ggtgtcaaac gtgcgcgtag cctggctgaa
    13201 tatcttgatg ctcctatcgc cattatcgac taccctcaag acgatgcaac tcgtaacgaa
    13261 ggttatatta ttggtgatgt tgaaggtaag aaagctatct tgattgatga tattttaaat
    13321 acaggacgta ccttctctga agcttctaaa atcgttgaac gtgaaggagc tacagaaatt
    13381 tatgctgttt ctagccacgg tctcttcgtc gagggagctg ctgagcttct tgacaatact
    13441 aatattaaag aaattcttgt gactgattca gtagcaacaa aagaaaaaac tcctaaaaat
    13501 gtatgctaca tcactgctag tgagttaatt ggtgatgcta tcgtccgtat tcacgaaaga
    13561 aaaccagtca gcccactctt tgcctacaat aaaaagaaat aaggtgattc tttgatttat
    13621 ttggacaatg ctgcaacgac tcctatgtca gcagttgcta tttcagctat gaccaaggtt
    13681 atgcaagaaa cccacggaaa tccttctagt attcatggtc atggtcgtca agctggcaaa
    13741 ctcttgcgag aagcccgtca ggaactagcc cagttactaa ggacaaaacc tcaacatatc
    13801 tttttcactt ctggtgggac tgaaggcaat aatactacca tcattggcta ctgtcttcgt
    13861 caccaagaac aaggaaaaca tatcatcaca actgccatcg agcaccatgc tgtccttgaa
    13921 acaattgatt acttggttca acactttggg tttgaagcaa ccattatcca gccagaaaat
    13981 caagaaatca cagcccagca aattcaaaag gctttacgtg acgatacgat tttggtttct
    14041 actatgtttg ccaataatga gacaggaaac ctacttccca tcgctgaaat tggccaaata
    14101 ctcaagcaac accctgctgc ctatcatgtt gatgcagttc aggctattgg taaaatccca
    14161 attcattcag aagaattggg cattgatttt ctcactgctt ctgcccacaa attccatggt
    14221 cctaagggaa tcggttttct ctacgcatct agcatggact ttgattccta tctacatggc
    14281 ggagatcagg aacagaaaaa acgtgcagga actgaaaatc tgcctgccat cgtaggcatg
    14341 gttgcagccc taaaagaaga cctagaaaaa caagaagaac attttcaaca tgtacaaaat
    14401 ctagaaactg cctttctggc agagctggag ggcattcagt attacttgaa tagaggaaaa
    14461 catcatctcc cttatgttct caatattgga tttcctggtc agaaaaatga cctcttactc
    14521 cttcggctag atttagctgg aatttcaatc tctactggct cagcctgtac tgcaggcgtt
    14581 gtccaatcca gccatgttct taaagccatg catggcgcaa attcagaacg cttgaaggaa
    14641 tcccttcgca tcagtttgtc gccacaaaat accgttgaag acctacaaac cctcgcaaaa
    14701 accttaaaag aaattatcgg aggttagcca tatggcattt gaaaaaatca ttcagttaaa
    14761 aaattgtcgt tacgattaca ctcttagccc ttctgttaaa aaattcaccc tcaaagataa
    14821 cacctttttt gaaactaagg ttggtaacta tgaactgact cgccttttgg aaaaagtgcc
    14881 aaacagcggt gaaggcttcc aactcaaaat catcattaac aaggaactta caggggctaa
    14941 aatcaatatc actgacaagt ttggccttcg tctagttgat attttcaaat cagaagacca
    15001 ccatattcat caggaaaaat tctacttcct catggatagc ttggtagaac gtggtgtctt
    15061 tacaaaatcg gaaagataga gccaaaatgt ttgaactgac ctataaggac tgctatcatg
    15121 tagagcgtac tctcaagtat gaggatcatg aggctctcat gttgactttg tcaggatgtg
    15181 taaccttacc agatacactt tatgtgactt ctctgacttt taggggcaaa aaagtttatc
    15241 aggggctggt cggagacctc taccgttttc tatctcatgc agatttttta catcaaaact
    15301 aagatttttc ttagtttttt cttatttttg ttgatttttt cacaatgttt ctataaaata
    15361 gaagaataga aaggttgtga ttttgtgaaa gataaacagt ttgctattcc aaaagctaca
    15421 gcaaaaagac tctctctcta ctatcgaatt tttaagagat ttcatgcaga aaagattgaa
    15481 cgtgccaact ctaagcaaat tgcagaggct atcggtattg attcagcgac cgtacgtcgt
    15541 gatttttcct attttggtga acttggtcgt cgtggttttg gctatgatgt caaaaaatta
    15601 atgacatttt ttgccgattt gctcaatgac aactctatta ccaatgtcat gctggttggt
    15661 attggaaata tgggccatgc ccttctccac taccgcttcc acgaacgtaa caagatgaag
    15721 attatcatgg cctttgacct agacgaccat cctgaagtcg gtacccaaac tcctgacggg
    15781 attcccattt acgggatttc tcagatcaag gataaaatca aggatgctga tgtgaagact
    15841 gctatcctaa ctgttcccag cgtcaagtca caagaggttg ctaatctctt ggttgatgct
    15901 ggtgtgaaag gaattctcag tttttcacca gtccatctgc atttaccaaa agacgtggtc
    15961 gttcagtatg tcgatttgac aagtgaactc caaaccctcc tctacttcat gcgaaaagag
    16021 gattagaaag cgaaaatcat tttatgaaaa aaccagttat tgggattaca ggaaacgaaa
    16081 aaactcatcc agatgatgac atcatgatga gctacgcagc aaaaggcttt gttgaaggcg
    16141 ttaaagatgc tggagggatt cctatcatcc taccgattgg tgatcaagaa atggcctgcc
    16201 actatatcag tttgattgac aagctcatct tgacaggtgg gcaaaatgtc gatccaaaat
    16261 tctatggcaa acccaaaacc attgatagcg atgattatca ccttcaaaga gatatcttcg
    16321 aactggccct catcaaggaa gctattaaac agaaaaagcc cattttctct gtctgccgtg
    16381 gtacccaact ctttaacgtt gccatgggtg gaactttgta ccaagatatc gaagaccatt
    16441 ggcaggattc ttctgttgag tacacaactc aacgcttggt aacagaacca gataccgttc
    16501 tccaagaaat ctatggagaa atctctcata tcaactcctt ccaccaccag agcatcaagg
    16561 acttagcacc aaatttaaaa gttgtggctc atgatcctaa agatggtatc attgaggctg
    16621 tcatgagtac ggatgatgtc gcctttctcg gtgtccaatg gcatccagaa cttctttttg
    16681 aaaatcgtcc caaagataag aaactctttg actatgtcgt taatgaactt tagattaaat
    16741 ctgtcttttc acgataacta aagtaattag aatgagagac aatcaaatgg tccaagagaa
    16801 caatccccat cagttcgcag gcttctttaa caagtttagt gacatgatca tcattttggc
    16861 taggcgctac cgctcctgaa agatgattgt ggaccaagat aagagaagtc gccatatgct
    16921 tgattgcata gtgcagaatc tctcgcggtt cagcgatact acgagttaca gaaccgataa
    16981 aaatggtctg ctgatggatg atttgatttt gagtattgag atagagtgcc accaggtgct
    17041 cttgtttttt atcccctaat tcctgctgca tcttcttggc caacttttga ctgctgagaa
    17101 tactttccat ttcaagagtc tcgtgtttgt gaatacgatg ccccagttca atcatagctt
    17161 gtaattctat ggccttaaca cgcccaatac cagacaaact ctgcaattcc tgcagggtca
    17221 tttttttcaa atccgttagg cttgaaagat tgttcaagac tttttgggca atttcaaaaa
    17281 cgctagcttg acgtgttcct gtcctgagta aaatagctag caactcttgg ttactaagcg
    17341 cttcaactcc ttccttggcc agcctttctc ttggtaatag tgaatcttct tggaatgaaa
    17401 tactgtacat aaaaatcctc ctcactttat tattcgtgag aaggatggaa aattagattt
    17461 ttttctcaat tggagccaca ctggctaaaa gttttttcaa acctacttct gggaaattga
    17521 ttttcaattc ctgcctagca ccgctacctg aaacttccag aacagttccc tctccccatt
    17581 tcttgtggag agcaatgtca ccaatggacc aatttgcctc gctagatgct gattttgcgc
    17641 cagctgtaaa ttgaccaaat ggaagaacgc ttgactggat tgattttggg gcagcaccgc
    17701 gtttacggtc ttgaagagcc tgagccaaac tcataccttg accaaaggaa atactaccac
    17761 tgctatatga tgccttaaag cttgtatttg caggacgagc cagaccttga tactcaagca
    17821 agtctgaact gatttcgtta ataaaacgag tcggacggtt ataattggta cgaccaaaaa
    17881 gcaagcgtga gttggcattg gtcagataga gaattttctc tgcacgcgtg atacctacat
    17941 aggctagacg gcgctcttct tctaattcat ctggatcttc agtcgcacga ctaagtggaa
    18001 agacattttc ttccatccca atcaaaaaga caactggaaa ttcgagacct ttggcagcat
    18061 gcagggtcat caaggtcact tctgatgtct cctgactacc tgaatctgtg tcggcaatca
    18121 aagccaagtc atttaagaaa cgactcagtt tgtccagacc agtttcctct tctgtcacat
    18181 cagtggtgtc atcaaagttc ttcgtaacag aaagaaactc ttcgatattt tcaacccgtg
    18241 ccttgctttc tagagtcgct tgggcgttaa gaatatcgac ataacctgtt ttttctagga
    18301 cggactcaac caactctgta atgcttaagt ggtctagctg ctcccgcaaa tcaagcatca
    18361 tattggcaaa atcccagata gattgggctg ccttaccctt gataccagac aacataatat
    18421 tagcagaagc atccagcata gacatatttt gcaaatttgc aaaatcacgg attttctcaa
    18481 ctgtacctag accaattcca cgtttaggct cgttgataat acgctcaaaa ctaatattgt
    18541 cactcaaatt agcaataagg ttgagataag caataatatc gcgaatttcc ttacggctgt
    18601 agaatttggt tccgccaacc atggtataag gaatgttaga cttgagcagg gcttcctcaa
    18661 ttgtacggga ctgagcatta gtccgataga gaactgcaaa atccttatga aggaagtttt
    18721 gactgcgact aagttcatcg atggttctgg ctacaaatac agcctcatcc agctcatcat
    18781 cggcacgata gtaaacgatt tgctccccat cagcgttttg agtccagaga tttttaggac
    18841 ggcgattttt attattttta ataacctcgt tggccgcttg gagaatggtt ttggttgagc
    18901 ggtaattttc ctccaacaaa acaaccttgg ctttggggta atccttttca aagtccaaga
    18961 tattctgcat atcagcacca cgccaaccgt agatagactg gtccgcatcc ccaaccacac
    19021 agatattttt aaaacgggaa gccaagagtt tgactaattg gtactgagcg tggttggtat
    19081 cttggtactc atcaacgtgg atgtattgga atttttgctg gtagtaggtc aaaacatcag
    19141 gattttgatc aaagagacgc aaggtcagca taatcaaatc atcaaagtca acggattcag
    19201 actgacgaag ttctttttga taggctgtat aacactgggc cacaatttgc gtatacatat
    19261 cgccagcttg ggcagcataa gcaacatcat caatcaaatc attcttagca ttggaaatgg
    19321 tccccaaaat agttcgttca ttccattttt taggatccaa gttcaactgt ttgagaatac
    19381 gtttcatgag cgttcgctgt tcaccaggat ccacaattgt aaaattacga ttgtagccaa
    19441 tatggtccgc atcgcgacgc aaaatacgca cacacatgga gtggaaggtc gcaatcagac
    19501 agtcctgagt cgctggattg aggctataag cacgctcttt catctcacgc gcagccttgt
    19561 tggtaaaggt aatggccaag atattccaag gattgaccag cttttcatca atcaaataag
    19621 cgatacggtg ggtcaaaaca cgagtctttc cagaaccagc ccctgccatg attagcaagg
    19681 gaccttctgt cgtttgcacc gcctcagcct gacggtcatt cattccattt aataatgcgt
    19741 tcatcttctc ttccttactc ttgaagtcaa tatttctatt atatcagaaa tcagggaaaa
    19801 tagaaacttt acggggagta gcaaaatata gtggattgaa actagaatac tacactgtgg
    19861 gtttctaaaa cactcgactt tttcacccaa ttttttcata aactagctca atacctca
//
LOCUS       DBERDS010000037        19275 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.037, whole genome shotgun sequence.
ACCESSION   DBERDS010000037 DBERDS010000000
VERSION     DBERDS010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.037"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(150..581)
                     /locus_tag="ACL73E_001478"
                     /pseudo
     CDS             complement(150..581)
                     /locus_tag="ACL73E_001478"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(673..1005)
                     /locus_tag="ACL73E_001479"
     CDS             complement(673..1005)
                     /locus_tag="ACL73E_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0801433.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(1018..1791)
                     /locus_tag="ACL73E_001480"
     CDS             complement(1018..1791)
                     /locus_tag="ACL73E_001480"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0801434.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGIGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(2239..2994)
                     /locus_tag="ACL73E_001481"
                     /pseudo
     CDS             complement(2239..2994)
                     /locus_tag="ACL73E_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(3132..4754)
                     /gene="groL"
                     /locus_tag="ACL73E_001482"
     CDS             complement(3132..4754)
                     /gene="groL"
                     /locus_tag="ACL73E_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGS0801435.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4770..5054)
                     /gene="groES"
                     /locus_tag="ACL73E_001483"
     CDS             complement(4770..5054)
                     /gene="groES"
                     /locus_tag="ACL73E_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGS0801436.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKAAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5324..5719)
                     /locus_tag="ACL73E_001484"
     CDS             complement(5324..5719)
                     /locus_tag="ACL73E_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGS0801437.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5797..6558)
                     /locus_tag="ACL73E_001485"
     CDS             complement(5797..6558)
                     /locus_tag="ACL73E_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGS0801438.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6591..7217)
                     /gene="ytpR"
                     /locus_tag="ACL73E_001486"
     CDS             complement(6591..7217)
                     /gene="ytpR"
                     /locus_tag="ACL73E_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGS0801439.1"
                     /translation="MIFTYNKEYVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7233..7550)
                     /locus_tag="ACL73E_001487"
     CDS             complement(7233..7550)
                     /locus_tag="ACL73E_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGS0801440.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(7547..7846)
                     /locus_tag="ACL73E_001488"
     CDS             complement(7547..7846)
                     /locus_tag="ACL73E_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGS0801441.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDLFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFIYENEDLVYEEEVL"
     gene            complement(8044..8124)
                     /locus_tag="ACL73E_001489"
     CDS             complement(8044..8124)
                     /locus_tag="ACL73E_001489"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801442.1"
                     /translation="MASSGKMLRNTYTPDSYYVGNLGAWQ"
     gene            complement(8131..8322)
                     /locus_tag="ACL73E_001490"
     CDS             complement(8131..8322)
                     /locus_tag="ACL73E_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGS0801443.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(8483..9157)
                     /locus_tag="ACL73E_001491"
     CDS             complement(8483..9157)
                     /locus_tag="ACL73E_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801444.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(9163..9609)
                     /locus_tag="ACL73E_001492"
     CDS             complement(9163..9609)
                     /locus_tag="ACL73E_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGS0801445.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9711..10226)
                     /locus_tag="ACL73E_001493"
     CDS             complement(9711..10226)
                     /locus_tag="ACL73E_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGS0801446.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(10223..10585)
                     /locus_tag="ACL73E_001494"
     CDS             complement(10223..10585)
                     /locus_tag="ACL73E_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HGS0801447.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10651..11682)
                     /locus_tag="ACL73E_001495"
     CDS             complement(10651..11682)
                     /locus_tag="ACL73E_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0801448.1"
                     /translation="MDFLLMGALFIVLPQTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATVHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(11689..12510)
                     /locus_tag="ACL73E_001496"
     CDS             complement(11689..12510)
                     /locus_tag="ACL73E_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801449.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMPFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLM
                     RTTNDITQVQMLITMDLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            complement(12527..12997)
                     /locus_tag="ACL73E_001497"
     CDS             complement(12527..12997)
                     /locus_tag="ACL73E_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGS0801450.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(13121..13837)
                     /locus_tag="ACL73E_001498"
     CDS             complement(13121..13837)
                     /locus_tag="ACL73E_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0801451.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14718..16127)
                     /gene="ply"
                     /locus_tag="ACL73E_001499"
     CDS             complement(14718..16127)
                     /gene="ply"
                     /locus_tag="ACL73E_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGS0801452.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(16138..16548)
                     /locus_tag="ACL73E_001500"
     CDS             complement(16138..16548)
                     /locus_tag="ACL73E_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801453.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDYLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(16541..17149)
                     /locus_tag="ACL73E_001501"
     CDS             complement(16541..17149)
                     /locus_tag="ACL73E_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801454.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17162..17620)
                     /locus_tag="ACL73E_001502"
     CDS             complement(17162..17620)
                     /locus_tag="ACL73E_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGS0801455.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17745..18141
                     /locus_tag="ACL73E_001503"
                     /pseudo
     CDS             17745..18141
                     /locus_tag="ACL73E_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(18882..19142)
                     /locus_tag="ACL73E_001504"
     CDS             complement(18882..19142)
                     /locus_tag="ACL73E_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801456.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT         5773 a         4260 c         3347 g         5895 t
ORIGIN      
        1 ttatatcgtt taatacaaaa aatacgaaaa tgattagtat aaaaaataca ggtcaacttc
       61 gtatcaaaaa catttttttg tatttccaca tagcatcaat catttagtac aatattttaa
      121 aaacaatatc ttaacagaga aaatgatatt taatctatca gctcatttaa tcgtttttga
      181 aaatataaag caatactttt agattcaata aactcaaaat attttatgac attgtccatt
      241 tgtttaattc cagattcttt agattctgtc aggtatattt tatatccttc tacaaatttg
      301 aatgtagatt tttcaaaaac ttttgtgtca tcttttaata atttttgtaa tttcatttca
      361 aagtagtctg catatattag atgtgaattt tcaaggcaac agaaccaaaa atttaaacaa
      421 gctgacacaa ctaaatttct attcttgccg attttttcgt aataatgtgt acgctctagt
      481 atttcttttc cgaccatgta aatataatct atttcaaaaa gatgatataa attaccaatc
      541 agcgttatct cataggactc ccatcgttcc ttctggaata aatagtcata tactaaattt
      601 agatcatctc tactaactac atgattacaa tctagctgat ttcataatcc ctgaaccata
      661 attgtattta ttttatgagt ttttcccact cttctcaaaa agtttttgtt gcttattttt
      721 tattacctcc aatcctttaa tattcaaact ataaaaattt ggagataaat taaccaaaaa
      781 atcatcacgc tccgatcttt tataatgttc taagtgatta caaaaattct ctatcgaaac
      841 attgatattt gataataatt caaaaaatgt tgaaagagaa atttcatttt ctcccctttc
      901 aaatctagaa agttgagatt ttgatataga atcagctgca gcatactcta aagaatatcc
      961 gtttaatttt ctaaaatatc gaaaagcttc tccgtaattt ttcacacttt cattccctta
     1021 actttctttt cgagcgataa acataccata ttctttagga atgatcaaca taccattatt
     1081 aaactcactt tccaatcttt tacgtattat ttcctcttct agtgaaccta tttctgaaat
     1141 tcctttaaac gattggatgt atttaactag gtcatctata ctagttacct gtaactcatc
     1201 atcatagagt aatgtatcga cagagttaaa atacctactc aggtaccttt taccattttg
     1261 taaagtaaac gttctatttt ctaaatcttg attaacctca tctttaaata aacttgccaa
     1321 ataatttaca actccatttt caccaaatgt agcacagtaa aaaattcctc cggtttttaa
     1381 gaccctattc acctcagaga gagctttagg aatatcattc acatgatgta gaagcatatt
     1441 agcaataaca atatcaaaag tttcattctc aaaagaaatc ttttgaatat ccattatctc
     1501 ataattgaca ttgtttctat ttccaatcac tgacttcgtt gattttacca tatctttaga
     1561 aaaatctgta acaatcaact gcttcatttt atctatagaa tcactattac ttttccacaa
     1621 ttctcctata ccacatccca attctagaac ctttacttca tcagtgattt ggtagttaga
     1681 aaatatccaa ttattaaatc ccaatttatt ttttgaatac ttcttatgca attctactcg
     1741 aatatcaaga ttatcatgac ttttatattg ttcaattact ttatcaatca ttttaaatga
     1801 cctccactct ataatttggc attatatcac aagaataaag atagtgttaa ataagttgta
     1861 taaatgcaaa aaaggaataa atccattata gcagagttac aacacattac tagaaagaga
     1921 tttattccta cgactcagtt tggcatgctt aacttcctaa ctcaaaaaca aagcatcgat
     1981 taatttatcc gttcttcttt tgaaacagat ttgaactgat aattgctcgt tttaatttaa
     2041 gaagctcttt tgagcaaaac ttcatttttt taagagtcca acaatttctg tctatcgctt
     2101 ttctactagc aaaaaaaact accttgaggc aagttttcat ttatatatct aatttcgtaa
     2161 tagtatagta aaatgaaata aggacagtca aatcgatttc taacaatgtt ttagaagtaa
     2221 aggtgtacta ttctagtttc aatctactat aaatttgata tgagaatagt ctttctcaac
     2281 atccttaccc aacaagaatg ctgtagcgtc cttcttaact tgaaccaggt caatattctg
     2341 ggcttgggct gcatagacgc agccacaata acattgacga tagatatcat actcctcaca
     2401 catctctact gaacgtttgt agccttgatt tttcttgaaa tcgttgggaa gatagtgggt
     2461 cgtgtaaatt ttttgcacat cgattccgat gctgttgatg gtttgagaat tcttatgagg
     2521 actgatggtc aaggctgaac caaagtagtc aaagcccaag tccatagcca cttgcgctgt
     2581 tttatccagt cggtagtcaa aacaaacctt gcaacggtcg ccaccttcgg gctcctcctc
     2641 tagtccccta actagttttc ggtattaatt gggttcgtag ggagcttcta ggtactgaac
     2701 cgtatttcct gtccgctcat taaaatcact aacaaatttc ttggtgacat agacccgctt
     2761 atggtattct accttgggat ggatattaga attggcaaaa tagatggtca catctgcata
     2821 cttggtcaaa tattctagtg tataggtact acaaggggca cagcaaacat gcacgagaat
     2881 ggttggccgt tgctcatttt tctaccatac ttctaccatt ttctgcatga cacggtcata
     2941 attaatcttc tgattggggg gcatcttgca cagaatttct tctacatcga tcatgttctt
     3001 ctcctttttc tagtcttatt ttatcatata agttaggaga gctcaaatca atttagaagt
     3061 gaatattata aaaagaaggg ttagtcattc cctccttttg tgttttttat aagttgtttt
     3121 ctatagaaag cttacatcat cccgcccatc atacttggat ccattgctgg agctggggct
     3181 actggttctg gtttattggc tacgactgct tctgttgtca aaatcaagct tgctacagat
     3241 gctgcatttt gtagggctga acgactcact ttaactggat caatgatacc ttgatcaatc
     3301 atgttaaccc actcgccagt tgctgcgttg aatcctatac caagctcagc atttttcaaa
     3361 cgatcgataa cgatagatcc ttcaaatcct gcattgtgag caatttgacg aacgggttct
     3421 tccaaagcac ggagaacaat attacgtcct gttgcttcat ctcctgtcaa ttccaaggta
     3481 gcaacagctg gaatcacatt ggcaagagct gttccaccac ctgcaacaat accttcttca
     3541 acagctgcac gagtagcgtt gagggcatct tcaatgcgga gtttcatttc tttcaactca
     3601 gtttcagttg cggctccgac cttaataacc gctacaccac ctgacaattt ggccaagcgt
     3661 tcttgcaatt tttcacggtc aaattcagaa gttgtagttt cgatttgaga cttgataacc
     3721 gcaacacggt gagaaatcgc ttcaggattt cctgcacctt ctacaataac cgtgctatct
     3781 ttgtccacgg tcactctcgc tgcttgacca agagcttcaa ttgtcgcatc tttcaactca
     3841 agaccaaggt cttctgtgat aactgttccg cctgttaaga tggcgatatc ttcaagcatg
     3901 gctttgcgac ggtcaccaaa accaggtgcc ttgactgcta ctacgttgaa ggttccacga
     3961 atcttgttca aaacaagagt tggaagagcc tcgccatcca catcatccgc aataatcaag
     4021 agtggacgat tgctttggag aatgctttcc aaaagtggca agatttcttg gatattagaa
     4081 attttcttgt ctgtaatcaa aatgtacgga ttttcaaggt cagccaccat tttttcgcta
     4141 tcagtcacca tgtactgtga aaggtaacca cggtcaaact gcattccttc tacgacttca
     4201 agctctgttt ccataccacg tgactcttcg atggtgatga caccgtcttt gccaactttt
     4261 tccattgctt cagagatgta ctcaccaact ttttcagaac gagaagatac ggctgcaact
     4321 tgagcgatag cttctttatt ggcaacaggg atggcgttgt ttttcaaagc ttcaactgct
     4381 gcggcaactg ccgtttcaat cccacgacga ataccgattg gatttgcacc tgctgtgacg
     4441 tttttgattc cttcacggac gattgcttgg gtcaaaacag ttgcagttgt agttccatca
     4501 cctgcgatat cattggtttt tgaagctact tctgatacca atttggcacc catattttca
     4561 aaatggtctt ccaattcgat ttctttggca atggtcacac cgtcattggt aatcaaaggt
     4621 gaaccgaatg acttttcaag aacgacattg cgaccttttg gtcccaaggt tactttaaca
     4681 gtgtctgcaa ggatatcgac accacgaacc atggctgaac gggcatctga tgaaaattta
     4741 atttcttttg acatacttac tttctccttc tattcctcaa tgattgccaa aatgttagct
     4801 tcgcctacga tgatgtactt ttcatcgcca tctttgacat caagacctgc gtgggcttca
     4861 actaagacac gatctccagt tttaacactt ggagcaacca agtcaccgtt caaggtacga
     4921 acaccttgtc cagtagccac aacttgagct gctttggttt tttcttgggc tgagcctgca
     4981 aggacaaagc ccccaacggt ttgttctttt tcttctattt ttaagaccac acggtcccct
     5041 aatggtttca acatctgatt tcctccataa tgagatagat attattagca ctctttgaac
     5101 ttgagtgcta attcataatt ctattgtatc acttggtcag aaatagtcaa gaaaaaagtc
     5161 tgactttctc aagataaaaa gcctgagacc aactcagact ttttaatgtt tatactcaat
     5221 gaaaatcaaa gagcaaacta ggaagctagc cgcaggctgc tcaaagcatt gctttgatgt
     5281 tgtggataaa gctaacgtgg tttgaagaga ttttcgaaga gtattaaaat ggcaattctt
     5341 cctcttccaa gaccaaatct gccaaatctt ggcctgcatt attttcacgc atggcacgtt
     5401 gagcacgact ttctaagagt tggaatcctg tcacaaggac ttcggttaca tagttcatct
     5461 gaccattttt ctcaaagcga cgggtacgca attctccatc aacggaaatg agactacctt
     5521 tggttgcgta gcttgccaaa gtttctgcta gcctgcccca taggaccata ttgacaaaat
     5581 cagcttcacg ttcaccgttt tggtctttgt aacgacggtt gacagcgata gttgctcgcg
     5641 ctaccgactt gtcattgttg gttttgtgca attctggtgt agacgttaaa cgcccaatca
     5701 agataacttt attatacata ttttcttcct cctacttatc tattcgtagg aaatcaaaaa
     5761 aagttacaga aatttgtaac ttttcgagga aatttcttat tttttatgaa tcatgaaacc
     5821 tgtcgcctgt tgattggcca taatggtcat atctgtaatc tgaacacggc gaggctgact
     5881 ggtcacatag actactgtgt ctgcaatatc ctgagcttgc aaggcttcta ttccttggta
     5941 aacggacgca gcccgctctt tatcaccatg aaaacgaaca gttgagaaat ctgtttcgac
     6001 aatcccaggc tgaatggttg tcaccttgat atccgttgcg atggtatcaa ttcgcagtcc
     6061 atccgaaaag gtcttaaccg ctgccttggt agctgagtaa acagcggcac cagcataggc
     6121 gtagattcct gcggttgacc ccatattgat aacgtgacct tgattgactt ttatcattgc
     6181 tggcaagaaa cagcgagtaa ccgccatcag acctttaaca ttggtatcca acatggtcaa
     6241 catatccaac tcctcatagt cttgataggg agccaagtca agagccagtc cggcgttgtt
     6301 gaccaagata tcaatcctcc ctatcgtttc tagaatatca gagcaaacag tcttcaccat
     6361 gaccatatcc gtcacatcta gtggaaaagt ccagacagtt tgatttggaa agcttactgc
     6421 aaactccgac ttgaggattt ctaatctgtc tatccgtcgt cctgttagaa cgacatcctc
     6481 accctgctcc agataagcac gcgcaatcgc ttcaccgatt cctgaggttg ctcccgtaat
     6541 cactacattt tttgccatct tatttccttc tatcagatgc tgacaagttc ctaggcagtc
     6601 cagtgtttcg ctgggtcgaa cggtgttccg acaacttggt cttctgataa ttcaagcacc
     6661 ccacgttttt gcggagcatt tggcagatgc aattcacgag gactgcacat cataccaaaa
     6721 ctcttttcac cacgaagttc acctgggaaa atgagattcc cttttggcat catagctcca
     6781 ggaagcgcga caatggtttt caaccccaca cgcgcattgg gagctcctgc aacgatttgt
     6841 acagtcttat cacttgcgac tgcaacttgg cagatgttga ggtggtcact atctggatgg
     6901 gctaccatct caacaatttc accgacaaca aacttaggtt ccttatcatt aacaatttct
     6961 tctgtaaaac cttccgcctg caactcttgg ttcaaacgag cgacttgctc atctgtcaaa
     7021 aagacttgac cgcgctctgc aatttcaaat aaacttgaaa cttcgaaaat attccaagcc
     7081 actgtttccc cattatcttt gagaaaaaca cgggctacct tgcctttgcg ctccacatcc
     7141 agtttggcat ctccgctatt tttcacgatg accataagga catcaccgac atattctttg
     7201 ttatacgtaa aaatcattgt ttcctttttc tcctatttca atcctgctaa aaaatcattg
     7261 atttgttgct tgcttttacg gtcgcgattg acaaaacgac cgatttcctt gtccttttct
     7321 agaacaacaa ggctaggaat tccgtaaaca tcccagagtt tggccaaatc catatactga
     7381 tctcggtcca ttcgaataaa ggtgaactct ggattggtct cctcaatctc tggtaaggca
     7441 ggataaatat aacgacaatc gccacaccag tctgccacaa aaaggaagac cttcttgccc
     7501 gctttttcca ctaaagatgc taattcttct aaacttgctg gctgtatcat aagacttcct
     7561 cctcatagac taggtcttca ttttcataga taaaggtata atgacggcca tcctcaaaaa
     7621 tgacgccacc aaccaagctc tccagactgc tttcgtaaac ttgaacatag agggtcgcaa
     7681 tttcccccat gtcggaaaaa aggtctcgca caatctctgt caactcttcc tgagtcttca
     7741 tgagcttacg gtcatctgca acttttttcg tagcaagagc aaggcttccg atacctagca
     7801 gagccaagcc tgccatccac atttttttag ctttcatacc attcatttta acacaaaaaa
     7861 ggcttcagga caaatgagga agcagcagaa aagcaagtaa aaagcctctt cctttaagga
     7921 aaaagacttc ttatactaag agcaaactag gaagctagcc gcaggctgct caaaacacgg
     7981 ttttgaggtt gtagataagg cgacgttgac gtggtttgaa gagattttca aagagtatta
     8041 ttcttattgc caggcaccta agttgccaac gtagtaacta tcaggtgtgt aggtattgcg
     8101 aagcatctta cctgatgaag ccagataata ctacttgcca ttgtctttga cccaatcatt
     8161 cgcaatcatg gaaccagaag aacttacata ataccattct cccttgtcat aaacccaagt
     8221 actgactttc atggttcctg agcaattaaa ggcaaaaaaa ctgtccaata tcattcgttt
     8281 tttaaaagca tttgacacta catcatctac gctgtagtac atagatacat caaacgtaaa
     8341 agccaaaata tcgaaaaata tacaactttt aaaggcagca tttcattttt taaagtctaa
     8401 caaccataga actgaaatca gagcaaggca tcaatttcct actcttagta cgtctatttt
     8461 gatggttgaa gtgaagattt ttttatttaa cgtagacaat ttccaacttc ccaaaagcca
     8521 catctccacg gatagtcaag gttttgctgg ttggggctac aggagcgtca gccttagctg
     8581 caccaaagga ggtttctact ttcaaatcta cacgccagtg ttgtggaaca tagacggttg
     8641 cattcccgaa ggccacttca atatttaaag ttgcaaaatc acctagcatc tctgcattat
     8701 catagtagat tttagcatcc ccaaaagcga cttccacttg gtcatctacg agatcttgat
     8761 cttgcttata gaaggtcccg ctaccaaaag cgacttcctt atccgtgacg actgtttttt
     8821 tcccattgta ccaccatttt ttttcattcc agaacttact tgaatgcgtc agataaccaa
     8881 caccaagtac caccaagatg ctagcccaaa taagagaatg attggtaact ggtaacaagt
     8941 cataagcgta atttgcaatg atgagcgcca gtaaacctgt aaaaactgcc gaagtgagat
     9001 gacgtctaag gatggactca atggacttat aagcaaaaaa aacaatacct agtaaaggcc
     9061 atattttacc atccaaagaa ggaattccaa aattcccttg cagcaagatc caagctgcta
     9121 aaaccaacaa aacaatacca aatgctttct ttttcatgtt ttttacctca tgtttcttag
     9181 attttctttt aggagggatt ggtaatgccg tgagacatga acctccttgt gcgtctgata
     9241 aaaggaaatg gtgcccgttc ctgaaaagga cttgtccact gagtaaatct gacggatgtt
     9301 tgcgatcgtt gacttggaaa ctcgattaaa atagcgaggc aagatagact ccaactcata
     9361 gagcttgagg cgaacctcat aagcttcctt ctggttatga gcgtagatct tgctcccttc
     9421 tgtttcaaag aagagaattt ctgacaggtc tagataatat tcacctgtcc ccttgtaaaa
     9481 agtcaacctc ggagcctttg actcttgcaa gagccgttgc aagtctgcaa tttcatctgt
     9541 caaagtgggg gtcttgatga caatttcagt ctcctctaaa ttgccgtcaa tctcaattcg
     9601 taacttcatc acatctcctt tctgactcta ctatatcaaa gctaagttag gaatacaagg
     9661 gcaaaaaagc aagtggtcaa tttgaagcag taagtggttg taggactagc ttaacttaca
     9721 tgtaagaata ggaagaaaag gaatccccac accaaaccac aagcatagcc aaccaagaca
     9781 tccttgggat aatgaacacc ccctaaaacc ctcaccaacc ccagcaaagc tgaaaagatc
     9841 aagcatacta agccaatagg tagactagca tgcagacagg ccatggagat gatagttgcc
     9901 gaaaagacat ggcgactggg catcgaccgt cccgaactat ccttatcaag aaggggacag
     9961 atatcccaag tttcataagg tctcgggtga ttgattttct tacgaaacag ggacaaggcc
    10021 acaaaacctg atgcaggaat aagcacacaa accccaactt gctgaccaag tcctagttgc
    10081 aggtaagtgg tgactagcaa gatcagatag accaggggca tggcgactgt catcaaacga
    10141 ttgaaactgc gtaataggaa taaaagaatt ggacgactag ttagtctgga gctgatattt
    10201 cgataccatt cttgataatt tttcatttat gcttctcata cttttctaga acttgttgag
    10261 atgttttccc cttggcaagc caatccacta gcttgtccaa gcgacgtatt tcctgcatca
    10321 gaggatcatc aatttcctca atacggacac tgcaaatctt ccctgtaatt gcaattcgtt
    10381 cagggacata atatggtgct tgtctaaaaa aatctccgta agtaacatcc ctatccagac
    10441 aagcaagaac atcactcact tcataccctg tcaaccaact ggtcacttgg tgaactgact
    10501 ctgcctttcc accctttcgc tcaacttttg caatcaaggc taagtagaca gcagcaaatt
    10561 tcatattgta taatttctga ctcatacttc tctctttcta tgtgtactag tataaataag
    10621 aaaaagaagg ccgtcaagcc ttcttttgat ttattcttct gcttcatctt ctgtaaattg
    10681 actattgtac aagtcagcgt agaagccacc ttgcgccatc agttcctcat agttgccttg
    10741 ctcgatgata tttccatctt tcatgaccaa gatcaagtct gcatttcgga tggttgacaa
    10801 gcggtgggca atgacaaagg atgtgcgtcc ttccatcaaa cggtccatgg ctttttggat
    10861 caattcctct gtccgtgtgt caacagaaga agtcgcctca tccaaaatca aaagcggtgc
    10921 atccttaaga agggcacgag caatagtcaa tagttgtttt tgtcctacag acaaggtcac
    10981 ggtgtcatcc aagatggtat catagccatc tggcaaggtc ataataaagt ggtgaattcc
    11041 cacagcctta ctagcttcca tcattcgttc atcactaatc cctatttgat tatagatgag
    11101 attgtctcga atagttcctt caaagagcca ggtatcctgc aagaccattg aaaaggcatc
    11161 atgcacttct gaacgcgtca tagccttggt atccacacca tcaatgtgaa tacttccctt
    11221 atcaatctca tagaatttca tcaaaagatt gacaatggtt gtcttaccag tcccagtcgg
    11281 cccaacaatg gcaacctttt gaccagcatg aactgtcgca gagaagtcat agtcttgaac
    11341 attgacaccg tccaccagaa tttctcctgc tgacacgtcg tagaaacgtg gaatcagatt
    11401 gaccagagtt gatttaccag aacctgttga cccaataaag gccactgttt gaccagtttc
    11461 tgctttaaag ctaacatgtt caataactgc ctccgaattt gccgcatagc ggaaggtcac
    11521 atccttaaac tcgacctgac ctttgaagtt ttcatcagtc agctgcactt gaacagggtt
    11581 ttggatagaa gaatgcaaat ctaaaacttg attaatccgc ttagcagaga ccatagtttg
    11641 gggaagaacg atgaagagtg ctcccatgag aaggaagtcc atgacaacct acatggcata
    11701 agacatgaaa acaatcatgt cactaaagag aggcagacgc gctatcggag cagcgtcgtt
    11761 aatcacatag gccccaatcc agtaaatcgc cacactcaaa ccacttgaaa tccccatcat
    11821 gataggattc aaaatagcca taagacggtt gacaaacaaa tttaaacggg tcaattcatc
    11881 atttactgct gcaaattttt cattttgata atcctctgca ttgtaggcac gaacgacacg
    11941 aatacctgtt aaactctcac gagtgatact gttcagttta tctgtcagcc cctgaatcaa
    12001 ggactgtttt ggaaaggcta gcgtcatcaa aacggtcgtc atcaggacgt tgacaatcac
    12061 tgccacaagt acggcccaga gccagtattc tgaatgacct aaaatcttcc caatagccca
    12121 gatagccata attggaccac acgttaccac ttgcaagtcc atagtaatca acatttgaac
    12181 ttgagtaatg tcattggtag tacgcatcaa gaggctagga attgaaaatt tcttaatctc
    12241 tgtctgcgag taatccaaaa ctcggttaaa aatatcactt ctcagcctac tagtataaga
    12301 agccgccact cgggatgcaa aaaatccaac tgcaactacg gacaagaagg caagaaaggg
    12361 cattcccatc atcatgcttg ccggctgcca caactcatct aaattagttc cttgactacc
    12421 tagcaaatcc gtaattttcg agatataggt cggcacttcc aactctagat agaccgaaaa
    12481 gcaagtaaag agaatggcta gtaaaatcat cccccattct tttctactaa ttcttttgac
    12541 taatttcttt attctctcct cctattccct tgatatttgc ctgtagttga ccgagaactt
    12601 tctcaaaaat cagtaattca tcttcatcaa tgtcttccat caactgcttg tctatgcgtt
    12661 caaaaaaagc cttaacctgt tgcatctgag aacgtgcttt gtccgtcaga cgaacaaact
    12721 tagcccgctt atcaacagga ctcgcctcca attccaccaa accattttgc actatacgct
    12781 taaccagatt actagcaaca gacttggtaa tattgagttc ctgctcgata tctttaatca
    12841 agaccaagtc ttggtttttc tcgcgattat ccaaaaaatg cacaacctga ccttgcggcc
    12901 cacccataaa ttcaatgccg caacgtttgg cttccttttg caccatcagg tgaatttgat
    12961 gaccaaaacg cttaaagact aacatcggtt tatccataat ctcccccttc taaataaaaa
    13021 tagttctctg gagaataatt aaatttctat gagaactatt ttcttgatta aaaaaatccc
    13081 aagtgatttt ctcacttagg atcatgttct ataggttaaa ttaaaaccca tctacgttcg
    13141 tataaatctt ttggacgtct tcgtcgtctt caagaacgct gtaaagtttt tcaaaggttt
    13201 caaggtcttc gcctgacaat tccacttctg actgaggaat catttccaat tcagtcactt
    13261 ggaattcttc aataccagac tcacggaggg caacgatagc cttgtgaagg tcagttggcg
    13321 ctgtgtaaac tgtgattgta ccttcttgtg cttctacgtc atccacatcc acatccgctt
    13381 cgagcaattg ctcaaagact gcgtccgcat cttcacctcc aaatacaata acacctttgt
    13441 tgtcaaagag gtaagaaaca gaacctgaag cgcccatgtt tccgccgttt ttaccaaagg
    13501 ctgcacggac attggctgct gtacggttga cgttagaagt caaagtatcc acaattagca
    13561 tagagccatt tggcccaaaa ccttcgtaac gtccttctgt aaaggtttcg tctgtgtttc
    13621 ctttggcttt atcaatcgct ttatcgataa tgtgttttgg cacttgggct tgtttagcac
    13681 ggtcgataac gaatttcaaa gctgagtttg attctggatc tggatcacct tttttagctg
    13741 ctacatagat ttctacacca aattttgcat atactttaga gttggctcca tctttagccg
    13801 ttttcttggc tacgatattg gcccatttac gtcccattag gaatctcctt ttttcacatt
    13861 ttaatctttc ttattataac acaagttttt ttgattttca ctagaggaaa tggattttat
    13921 tagcaaatca agctaggata gcactttacc tgctaagatg gtcttgcctt tctatcttta
    13981 tcaacagaca ctcatccaca ttcaaaaaac aaactagacc attatctgca aatagaaagt
    14041 ttcagccaag tttgacaaag tcagctcaaa ttactgtttg aagtttgtag atataagcga
    14101 caaaaacaat catactgcac cttttgttga cagtctactc cagacatatc atagttcaag
    14161 taaatacttt gaaatccaac agttcttata ggcgctattg tattctaaga aatcaataga
    14221 agagtttcta agcaaacctc taatactcaa taaaaatcaa agagcaaact agaaagctag
    14281 ccgcaggttg ctcaaaacac tgttttgagg ttgcggatag ggctgacatg gtttgaagag
    14341 attttcgaag agtataattt acgtgttcct aagatggaga agttagacta gtacactggc
    14401 acttctaaac cattgctagc aattgatttg ttcatattta atttcatttt ttccataaat
    14461 gggtattaga tataaacagc aaaatatttc cgatacgtgt cattcttgaa tttccaatca
    14521 tctaaaacaa gtaaaggata atcaatcccc tgtatatcaa ggaattggct acccttttta
    14581 cttttttaca catcctgttt gatagactca ttttaacatc acgagcatac tccaatggaa
    14641 atcgctaggc aagagataaa ctttcagata ttcgcagaga gctcatcgcc tctttttgtc
    14701 gcaaacattc ttctctccta atcattttct accttatcct ctacctgagg atagagagtt
    14761 gttccccaaa tagaaatcgt ccgcttacgc actagtggca aatcggtttt ttcataaacc
    14821 gtacgccacc attcccaggc aagcccggta cactctctaa ttttgacaga gagattgcga
    14881 acattccctt ttaaaggaat actagtggta aagtgagccg tcaaatcctg cccatttctg
    14941 tcccaagcct taggagtcaa gacttccttg ccttgatgat cataggataa ttcatcccaa
    15001 gtaatataat attgagcaac ataggcacca ctatgatcca gcagtaaatc tccgtttctg
    15061 taagctgtaa ccttagtctc aacatagtct gtactgtttt gaaaggtcgc aactacattg
    15121 tcacgtaaaa aagaagttgt ataggaaatc ggcaagcctg gatgatcggc tgtaaagcga
    15181 ctgccttctt gaatcaagtc ctctaccata tccaccttgc ctgttacaac tcgggcaccc
    15241 gaacttgggt cgccccctaa aataaccgcc ttcacttctg tattgtccaa aatctgcttc
    15301 cactctgtct gaggagctac tccttttatc aaagattcaa aagcagcctc tacttcatca
    15361 ctcttactcg tggtttccaa cttgagatag acttggcgcc cataagcaac actcgaaata
    15421 tagaccaaag gacgctctgc agaaattcct ctctgcctta aatcctctac cgttacagta
    15481 tcttgaaaca catctcctgg atttttaaca gcatctacgc tgactgtata ataaatctgc
    15541 ttaaaattaa caatctgaat ctgcttttcg cctgaatgga cagagttaaa atcaatatca
    15601 agagaattcc ctatcttttc aaagtcagaa ccaaacttga ccttgagttg ttccatgctg
    15661 tgagccgtga ttttttcatg ctgcattcta gctgggacat tattgacctg accataatct
    15721 tgatgccact tagccaacaa atcgtttacc gctccgcgaa cacttgaatt gctggggtct
    15781 tccacttgga gaaagctatc gctacttgcc aaaccaggca aatcaatact ataagtcatc
    15841 ggagcacgat cgaccgcaag aagagtggga ttattctcta acaaggtctc atccactacg
    15901 agaagtgctc caggatagag gcgactgtcg ttggtagctg ttacagaaat atcacttgta
    15961 tttgtcgaca agctccgctt ctttctttcg ataacaacaa actcatcggg tagctgatta
    16021 ccctctttga tgaaacgatt ttcaatactt tctccctgat gggtcaagag tttcttttta
    16081 tcgtaattca tagctagtat aaagtcattt actgctttat ttgccatctt ctacctccta
    16141 ataagttcct ggattgagtt gcataaactc agacttgttc agcgaaatca gccgtggttg
    16201 gactaagtaa tccaaaattt cctcgtacaa ttcttctgag acattgcgtc gccgtctggc
    16261 taaataagaa gtcggaatga ccgtattatc caacataaat accttatcta agtcaatcaa
    16321 ggttggtctt gtaaaaggat tacgagctag atccggctct tctatcataa agttcttgac
    16381 caaacgtctg gtcaagagag ctggtttgaa ggtctgattt ttaaccaact ctttgttttt
    16441 agtcatgctg ttgtcaatac agatatacat atgattcttc acagccaaat cgctactaat
    16501 agtcggaaaa ggcaaataaa gagctacaac atctcctctc ttaatcaagc aagagcaccc
    16561 ccttttctcc taatgtaaca tagacaggat tgaccaagtc ttctgattga ctcagaattt
    16621 ccaaagtttg agtttggcgc gctgtcaatt tagtagcatc ttgtctcttc aatacaaaat
    16681 gcttgtcgcc aataaccttg acaatataat ccttctccaa agctgactgg taaatccaca
    16741 tcagatgttg tctgtcctga gaactcaaga gagaaggatt ttcaagcctc ccgatagtct
    16801 gataaaaatc aaaaacagga gctaactcct gccaatctga ttggctagtt gtcaaggcta
    16861 gaaaaagggc tttgcgagct gatacttctt ggttagcctt gagagttact ttcccctcca
    16921 agttttttag aaatcgggaa actccagaaa gcaaattttt ctctaactgc gagaaataaa
    16981 aacctttcgt tcccagacat aagtctttca tgtcgctttc tctagcaaat aagagctcaa
    17041 acatttgata gtaaaagaaa aatatctggc actgggtcgc gctcatcttt tccttatcgg
    17101 cttctttttt taaccagagc aagggcgaca ggtagctgga ttgagacatt tcctctacct
    17161 cctactcttt tttaactgga gcatctgcac tagctgccac ttcttttgac tggatacttt
    17221 cccactggtt aatctcctct gagataagac cttcgcatgt cttgacaaat agggcaaaag
    17281 ccttggtctt tcctgcatat ttctccgttt ggcattgata gaggaatttt tctttctcca
    17341 ggagttgcgc agttttttgg taagaaatcc aattttcctt tgcattatac aaattgataa
    17401 tcccctcaca cagcaagccg agactggata aggcaaccga aatcaaacgg tagcgatcac
    17461 ctggcatagg aatagcacaa aagacagcta tgaggaaacc tgccacgatt tctgttattt
    17521 ttaatacctt atagcgccta cgatgttgaa cgcttttctt taaaaaatga gctatctgta
    17581 cgtctaatcg ctctgtcagg tacatttctt ctggcgtcat attcgtaact cctttcattt
    17641 actttgataa ccatagtata acatatttga atatcaaagt atagtaaaaa ctggactata
    17701 acttattaga ctccctgcga aacaaaatat ggtatagtag ttctatgaat tatgaagcaa
    17761 gtaaacaatt aactgataca cgatttaagc gtcttgttgg tgttcagcgt accacttttg
    17821 aagagatgtt agctgtatta aaaacagctt atcaaaaaag tcggacaagc tggtaaaatc
    17881 ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca aactccacgt
    17941 aaagccagca aactcaagcc gctaacagct gaagataaag cctataacca tgcgctatcc
    18001 aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aatgatttca
    18061 acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat tgctggtatt
    18121 atcaatcatg aactaggatt ttggtttcgc aggaagtcta ttatatatgc acagacatat
    18181 gaaatctttt tgagacagca gttatgatat atttatccat tcacaacatc ttctgtacta
    18241 atactacaat attggtacat tttgattaca caatcgtttc aaaaaatatg atggaagcct
    18301 gagtatttta tagtaattcc cttcctatca actagatcaa ccagttgagt gttgaatgtt
    18361 gaaacaccct agcctcagca aaggactatg atcagcattt cctagccaat aggacgctcc
    18421 aaatcaccta ttctaagtcc atcactagct tggtcagtaa gatacagact gcaaggcgag
    18481 actgacgtgg ttgatgagat tttggaagag tattacaatc atagattcac cagtagactt
    18541 gaccgcagat ttaactatag tagattgaaa ctagaatagt acatctctgc ttctaaaaca
    18601 ttgttagaaa tcgatttgac tgtcctgatc aatttgtcct gttctcgttt catttcacta
    18661 tactaaaaaa ccacctgaaa caaatcaagt gactagagga taaaaacaaa gactaggcaa
    18721 aaagttttga aaagcaaaaa acgcataata tcaggtcttg aaaaaccttg atactatacg
    18781 tttgattgtg ggaagattga cttcattttc tcctgaaatt gaagtttttt ctagtttcca
    18841 gatatagacg aattcaatat agccatctcg ctacaattat tttaaccatc gagaaaattt
    18901 ttcagaattt caaaaatttc attttgatcc aatgaaatgt catcattttg aagaatagtt
    18961 gacttcacag gctctaattc tatcacaaag cggtgtatgt ctgcttttac cgcactactt
    19021 gatgttatag ccgataactt ttcatctcct agcaaggaag ctgtcaaacg ggtaaggtca
    19081 ttcaaatgct ttttaatgga cttacttaaa ccttgagcac ctgtagcaga gcgttccctc
    19141 atatccagcc aagctttagc cttaaaaata attaatactc aatgaaaatc aaagagcaaa
    19201 ctaggaagct agctgcaggc tgctcaaaac actgttttga ggttgtagat ggaagctgac
    19261 gtggtttgaa gagat
//
LOCUS       DBERDS010000038        19246 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.038, whole genome shotgun sequence.
ACCESSION   DBERDS010000038 DBERDS010000000
VERSION     DBERDS010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.038"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(23..541)
                     /locus_tag="ACL73E_001505"
     CDS             complement(23..541)
                     /locus_tag="ACL73E_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGS0801457.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(578..706)
                     /locus_tag="ACL73E_001506"
                     /pseudo
     CDS             complement(578..706)
                     /locus_tag="ACL73E_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(768..1637)
                     /gene="rsmI"
                     /locus_tag="ACL73E_001507"
     CDS             complement(768..1637)
                     /gene="rsmI"
                     /locus_tag="ACL73E_001507"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGS0801458.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(1640..1957)
                     /gene="yabA"
                     /locus_tag="ACL73E_001508"
     CDS             complement(1640..1957)
                     /gene="yabA"
                     /locus_tag="ACL73E_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGS0801459.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(1997..2887)
                     /locus_tag="ACL73E_001509"
     CDS             complement(1997..2887)
                     /locus_tag="ACL73E_001509"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGS0801460.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(2884..3522)
                     /gene="tmk"
                     /locus_tag="ACL73E_001510"
     CDS             complement(2884..3522)
                     /gene="tmk"
                     /locus_tag="ACL73E_001510"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGS0801461.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(3742..4539)
                     /gene="proC"
                     /locus_tag="ACL73E_001511"
     CDS             complement(3742..4539)
                     /gene="proC"
                     /locus_tag="ACL73E_001511"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGS0801462.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLSRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(4543..5805)
                     /locus_tag="ACL73E_001512"
     CDS             complement(4543..5805)
                     /locus_tag="ACL73E_001512"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGS0801463.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADDDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(5815..6924)
                     /gene="proB"
                     /locus_tag="ACL73E_001513"
     CDS             complement(5815..6924)
                     /gene="proB"
                     /locus_tag="ACL73E_001513"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGS0801464.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7025..8920)
                     /gene="cbpE"
                     /locus_tag="ACL73E_001514"
                     /gene_synonym="pce"
     CDS             complement(7025..8920)
                     /gene="cbpE"
                     /locus_tag="ACL73E_001514"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGS0801465.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREEIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSSSPIGSYDSGQEINREYISWLESMGIQYINAASKDYDATVFDIRQDGLVNISTSYK
                     PIPSFQAGWHKSSYGNWWYQAPDSTGEYVVGWNEIKGEWYYFNQTGILLQNQWKKWNN
                     HWFYLTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQY
                     MGQWYYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWH
                     KKANDWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVS
                     IEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSV
                     NKSESEQ"
     gene            complement(8923..9810)
                     /locus_tag="ACL73E_001515"
     CDS             complement(8923..9810)
                     /locus_tag="ACL73E_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0801466.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(9800..10261)
                     /gene="lspA"
                     /locus_tag="ACL73E_001516"
     CDS             complement(9800..10261)
                     /gene="lspA"
                     /locus_tag="ACL73E_001516"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGS0801467.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10258..11166)
                     /locus_tag="ACL73E_001517"
     CDS             complement(10258..11166)
                     /locus_tag="ACL73E_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGS0801468.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLARKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11159..11356
                     /locus_tag="ACL73E_001518"
     CDS             11159..11356
                     /locus_tag="ACL73E_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGS0801469.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(11407..12078)
                     /locus_tag="ACL73E_001519"
     CDS             complement(11407..12078)
                     /locus_tag="ACL73E_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0801470.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLLLAVIYLLVFAGKKTFHFKWQLRYFIYLLLGYITSYMSDFLFSYFISLSS
                     NQISLNETIEMIGRQELPYFLLIVCFIGPIAEELIYRGVLMTTFFKNSPWYGDVLLFA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNIYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12132..12353)
                     /locus_tag="ACL73E_001520"
     CDS             complement(12132..12353)
                     /locus_tag="ACL73E_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGS0801471.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWKMEPVLTLL
                     VHGFCPRDTDDLGYIGGGNHLCKGSAARF"
     gene            12625..13434
                     /locus_tag="ACL73E_001521"
     CDS             12625..13434
                     /locus_tag="ACL73E_001521"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGS0801472.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(13615..14490)
                     /gene="aguB"
                     /locus_tag="ACL73E_001522"
     CDS             complement(13615..14490)
                     /gene="aguB"
                     /locus_tag="ACL73E_001522"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGS0801473.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(14500..15585)
                     /gene="aguA"
                     /locus_tag="ACL73E_001523"
     CDS             complement(14500..15585)
                     /gene="aguA"
                     /locus_tag="ACL73E_001523"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGS0801474.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(15582..16709)
                     /gene="nspC"
                     /locus_tag="ACL73E_001524"
     CDS             complement(15582..16709)
                     /gene="nspC"
                     /locus_tag="ACL73E_001524"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGS0801475.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(16709..17968)
                     /locus_tag="ACL73E_001525"
     CDS             complement(16709..17968)
                     /locus_tag="ACL73E_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGS0801476.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(17965..18825)
                     /gene="speE"
                     /locus_tag="ACL73E_001526"
     CDS             complement(17965..18825)
                     /gene="speE"
                     /locus_tag="ACL73E_001526"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGS0801477.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19081..19246
                     /locus_tag="ACL73E_001527"
                     /pseudo
     CDS             19081..19246
                     /locus_tag="ACL73E_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5591 a         4451 c         3463 g         5741 t
ORIGIN      
        1 tttttaaagt taaaaatata atttataata ctatcttctt ccattttctg attttagttc
       61 tgaaagttcc aaaaggtgca accgtattta catgaataaa cttatacact tcccaagtcg
      121 ctgttttagt cgcttcatca gcccactttc tcatatgcgg ttcaaataat tcttcctcac
      181 tcaacgaatc aatcattgca gagatagaat gaatattttc atttaatttt gctttcaact
      241 cttgcagaga taaatgagcg taggtatctg tgaaccactg atataattca ccaagttgat
      301 tccatttaaa tttatccgat ggtgttttta cttgaagccc ctttctttca tcttcttccc
      361 atttaagaac caagttggtc caaccaacct gataagcaag gttttctgct ggagttctgt
      421 caacttcatc agctctctta tcttttaaat tttctggaat attatcaaat tctaaaatat
      481 atttctcaaa tgttttctct atctcagctt ttagttcttc tttattttcg tatgttcgca
      541 aaaaatcacc ttctttctga tttatcaatc ctttgattta aaatgacctt atttttctat
      601 ttataccttc taagaacgct ataactgctg ctccaaccat cggtattccg tatgggctta
      661 ataaaaaact taataccaaa gcttctatac caagtgatac atctttatat tatcatcact
      721 aattaagtta aacagaaaca gacagaatta ttacatcctg tctcccttta ttgtttttct
      781 tcccagtcgt ggtaggcagc gtagagttga ctcttattcc actggtaaat cttagcgact
      841 tccttaatag cttgattttt cttcatacct tgctggatac gagcttggat ttctaagaac
      901 aagtcttcct cgtctttttc ttccacatcc tgactggcac cttcaacaat cagaagacat
      961 tcacccttga gagacgtttc agcaatgctt tccagcaatt cagaaattgt acctctttgg
     1021 tattcttcat agattttggt caattccctg accaagacaa cggagcggtc accgtagact
     1081 tctagcatat tttccaatgt atctgccaca cgatggggcg attcataaaa aatctgagtt
     1141 tcaggatagt cttttttcga gtcgaaaaat tgcttttgct ggcctgattt tctcggtaaa
     1201 aagccgtaaa agatatgtgg ctgcggcgct aaaccactgg caatcaaggc ggaaattcct
     1261 gcagaggcac ctggaactgt aacaactgca atttcttcct caatagctgc cttaaccaaa
     1321 tcatgaccag ggtctgaaat gctaggcaaa ccggcatcag agacctgagc aatactttgc
     1381 cctgctttca agaaaccaat caaatcagga attttttcct tggcattgtg ctcatgaaaa
     1441 ctgatctgct tggtggaaat gtcaaaatgc ttgagcaaaa gacctgtatt gcgcgtatcc
     1501 tcagcagcaa tccagtccac ttctttcaag gtctggatag cacgaaaagt catatcatct
     1561 agattgccaa tcggcgttgc cactagatac agcttgccat agggagactg ccccttaaaa
     1621 cttttttgaa tttgcatgcc tactccctgt ataacaactc atcacagaac atacattctt
     1681 cgtcctgctc tcgacgttgt ccataaaaat cattacatac gtgaaatcca tcacggtaaa
     1741 tgcgacggac actttcacga acatgcttgg ccttgacagg agcatctgct tccacctcac
     1801 ccaagcgttc tcgcaactta gaattttcca aacgaagagc tgtattttcc tctaccaggc
     1861 tcttgagatt tttcttgatg gcttccacat cggccaaggt taccaataac tgttgggaaa
     1921 aatcatccag cgcgtcaaat aattcttttt tgtccataaa acagcccttt cctttcttta
     1981 tcattcattt ttgagtttat atttctttca agaccagata ttccatggca ttttgaaagc
     2041 tgacattagc ttgccacatt tttctagctt ctagtaaatc ttgtagaatc actcttactc
     2101 ttacctgcaa gaggtcctgc ccacagagaa cttcaagaat ccgtaaaacc tgatcctgtt
     2161 tttccttatc atctgccaag ttggctaatt tggcaacctg tagataactt tcttttttct
     2221 tagctactaa ccaagtcagc aggcgttcac tttcatcgac caaggtccaa aaacttgcct
     2281 gattagccaa cttttctgct tcagctcgcg attgactaaa cttagctaaa agagtcgctt
     2341 ttttcttaac aagtcccatt tgttctaaga gtaagataag tttttcttct tgctttttaa
     2401 agtggaagat ctgagtccga cttcggattg tcggtaacat cttttcctca tcgctagtca
     2461 agaagaaaat ataaacttca ctctggggtt cttcgatgac cttgagcaga gaattggctg
     2521 cgttgggatg cattttatcc gcttgctcga tgataaagac ctgttgctgg ctttcaatcc
     2581 ctgcttgaga aaactgtccc accaattccc gaatgcgttc tgtcttgatg acctgattga
     2641 ctggcttaat caaggtgaca tctggaaact cttcctgttc aatcagcttg caacttcggc
     2701 atttctcaca tggtaagacg ccaactttat ccgtacaaaa gaggctctta gctaaaaatt
     2761 gcgctatttc caagcttcca aagaaacctg aaaagagata ggcgtgattg agctggtctt
     2821 gttctaagat acggacaaaa cggtcaaact gagctggttg ccaagccttt agttgatctt
     2881 gtttcatttg gccaagccca ttccgtcaaa caagacagcc ttggtagttt ccacaacttg
     2941 ctccaaaggg agactagcat caatcttgac aatgcgattt ccctctttat ccagaagaga
     3001 aaggtagcct tgacgaactt ttttatgcaa gtccaaccct tccaaatcca aacgattaac
     3061 ctcgcggtca ctattagcag caatacgagc cagcccttct tccacctcga tgtcaaaata
     3121 gagtgtcaaa tcgggtttga ggccatctgt cgcaaactga ttgagccagt caatggcttc
     3181 aatatctaag ccacgaccaa atccctgata ggcaacagaa ctatcgataa aacgatccat
     3241 gatgaccaac ttgccagctt caagggctgg aagaactttt tccaccaaat gctgtctgcg
     3301 actggcaata tagagaagta gctctgtttt agcatccatc tgagtatgac ttggatccaa
     3361 aatcacttcc cgaatcttct ccccaatcaa gactccgcca ggttcacggg tcgtcaacac
     3421 ctctactcct ttttcctcta aaattggtag cagagcctct aaaacactgg tcttgcctgc
     3481 tccctctggt ccctcaagag agactaaaaa tccttttgac atgtctaact catttctttt
     3541 ttactacttc tattctatca aaaaaatagg ggtttgtgac aatctttttg tcttctcatt
     3601 tcatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg tacttgagta
     3661 cggcaaggtg aagctgacgc agtttgaatt tgattttcga agagtatcag ccaccataaa
     3721 agaggcagat aaaactacct cttatttacc tagttcttgt gttcgtttat aggcttgatg
     3781 aactgcctcc atgactgtgc ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat
     3841 agtcgaaccg cctggactac aaacttgatc tttcaaaact ccaggatgtt gctggctttc
     3901 taggaccaat tgcccagctc ctaccacagt ttgggctgcc attttcaagg ctgtttctcg
     3961 tgataatccc gtctgaacac ctgcatctgc caaggcttca ataaagagat agacaaaggc
     4021 tggtccacag cctgcaagac ctgtcgctgc attgattaag ctttctccta attcaaccaa
     4081 gagaccagcc ttggataaaa gctgacaaaa gagctcactg tcctcagccc tgcaattagg
     4141 agacaaggca taactaatca ctccttgccc gatagaagca ggggtattag gcatcatacg
     4201 aataattcgg tgttgacttg ggataagact tgctagtttt tctaaggtca atccagctgc
     4261 catcgaaatc aaaagaagac tttctctttt ttcaaggatg gtctggtatt gagaaagcag
     4321 ttcagaaaac tgagcaggct taactcctag aaaaatcaca tctgcttctg caaacatttc
     4381 ttcattgctg gaagcctgac caccaaagtc tgcaatgaaa gcatctacct tagcttgact
     4441 acgattggca aggagaatct catctgacgt cctagtctgc aagacagatt ttgccaagct
     4501 agcacccata ttccccaaac cgataaatcc aatcttcatc tcttactccc ttatctgccc
     4561 atcaccagca accacatact tgtagctggt caactctttc aagcccattg gaccacgcgc
     4621 gtgcaatttc tgagtagaaa tccccatttc acaaccaaga ccaaattgtc ctccatctgt
     4681 gaaacgagtt gaggcattaa catacaccgc tgcagagtcc acttgatctg taaagtatgc
     4741 tgcagcttca gcattttccg tcacaatagc atccgaatga tgggtgctgt gggattcaat
     4801 gtgcgcaacc gcttcttcta aactgctcac aaccttaaca gcaaggacat agtctaaaaa
     4861 ctcggtgtca aagtcttggg tctcagctgc ttgacctgaa acaaactggc ttgctttgct
     4921 atccaagcgg aattgaattg gttccaaccc agcttctttt cgatctgcaa ccagcacttg
     4981 ctccaagcga ggaaggaagc ttgctgcctt gtcttcatga accagcagaa cctccatggc
     5041 attgcagaca gaaggacgac tggttttggc attgttgatg atagacagtg ccttgtcgtc
     5101 atctgcgtcc ttatcgacat aaacatggac aatcccagtt cctgtctcga taacaggcac
     5161 aatggcattc tcaaccactg cattgatcaa gccagctcct ccacgaggaa tgagaaggtc
     5221 tagatagccc ttggccttca tcatagcata actactttca cggctagtat cctccaccag
     5281 ttgaatcaca tttggatgaa tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat
     5341 ggcatgggtt gtttgatagg catccttacc actacgaaga acaaccgcat ttccactctt
     5401 aagagtcaaa gcagccgcat cagacgtcac atttggacgg ctttcataga taataccgat
     5461 gacacccata gctacacgtt tttttgtgat aaccaaacca ttttcaagct gacttgtttc
     5521 taaaacttca ccgattggat ctggtaaggc aaccacttca cgaattcctc ttgccatcgc
     5581 ttctatacga tctgcatcca aataaagacg atccaacatc acatctgaga ttttcccctt
     5641 agccgctgcc atatcgaggg cattagccgc taaaatttcc tcagtagcag ccactaagtg
     5701 atcagccatg gctagcaagg cttggttttt cacttcttca ctagctgtgt taatcgattt
     5761 tttaacagcc tgtacctgtt caaattgttc ttgtctactc accatagttt acctctaaaa
     5821 ttctgtaaaa agtagttgga tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa
     5881 gacacccttg gctttttgag aacgcaacat atcctccaaa gcagatgctc caaattgcac
     5941 gcgtcctttt ccaagtgatt ttccactttc cttatcaaat actgtcacga tatcaccgta
     6001 agaaaagact ccttctgctt caacgatacc agataagaga agactctttc catgttgaga
     6061 gagagcttcc gcagcccctt tatcaaccca aatagaacct tgactctgag catagaaggc
     6121 aagccattgt ttctgggtac gaagcccctt ctcttgagca acaaagtaag aaccatcctc
     6181 ggtctcctct gccgcctcaa tcatggaatc tgatttcaag gatgagcaga tataaacagg
     6241 aactcctgat tccgtcgcga tagttgcagc cttgattttg gttaacatac ccccagttcc
     6301 gtttgacgaa ccagctccac cagccatatc aataatctca cgattgatgg tctcgattct
     6361 ctccaagcgt ttggctcttg gatctgaatt aggatttcca gtatagagac cgtccacatc
     6421 tgtcaagaaa actaaaaggt ctgcttggac catcgccgct acttgagcac ttagagtgtc
     6481 attgtcccca accttaagct catcaataac gacactatca ttctcattga tgataggaat
     6541 tgccccacgg ttgagcaaaa ccgacaaagc ctgatgggca tttttataac gacgcttatc
     6601 cacaaagtca tcttgggtca gcaagatttg tgcagaaacg atttgacgca agagaagatt
     6661 ggtcgtatat tcttccaaca aaagtccctg ccctaccgct gctgaagcct gtttatcagc
     6721 aattttagtc ggacgctttt taaatcctaa ggctccaaaa ccagccgcaa tggcacctga
     6781 agacaccaaa atcaactcat gaccagcctc gtgcagcata gccaactgct gggtaatatc
     6841 ctttacctta ctacgtgata aacttccatc ctcatttgtc agagaagaag tacccacctt
     6901 aaagacaatc cgtttgtatt tcatagtctc actccgatta ttcatattta tccattataa
     6961 catgaataac aggaaataga aaagagttga taggaaaaag aaggccctaa aaccttcttt
     7021 tctactactg ttctgattcc gatttgttta cactcgtttc agagctttgt gaagttgagg
     7081 atgtcaaatc ttgactagtt gaaaaatttg taacactttc atgttgactc gtttctttat
     7141 tttcaagatc ctttttcact acttctttgg attcttttat ttctgaatga cttgtagttt
     7201 taattgtagc agatttctcg atcgaaacat ccactaacca ggcaccactt gaatccacag
     7261 tataaccttc tggtgtctta ccgttcacaa gtaattgacc attttctttc aagaagtacc
     7321 atttatcctt gtccttgatc caacccacag ctcgtgaacc gtctgtcttg tagaaatacc
     7381 aatcatttgc ctttttatgc cagccttgct tcatagctcc tgaatcttcc agataataat
     7441 gttgaccagc aacttctatc tcacctgtct tcatgacacc agtagaatcc atatagtacc
     7501 aggtttcttt atcttttacc cagcccattt tcatttcccc tgatggagca aagtaatacc
     7561 attgccccat atattgaagc catcctgtct tcatagaacc atcaacatcc aaataatacc
     7621 actgctcttt atcttgaacc caaccaattt ccatctgatt ttctttgtta aaataatacc
     7681 agattccatc aattttcttc caatttttag cagaagcacc agagtctgtc aaatagaacc
     7741 aatgattgtt ccattttttc cattgattct gtaataagat acccgtttgg ttaaagtaat
     7801 accattcacc cttaatttca ttccaaccga caacatactc tcctgtagaa tcaggcgctt
     7861 gataccacca gtttccatat gaactcttat gccaaccagc ttgaaaactt ggaatcggct
     7921 tgtaggaagt tgaaatgttt actaaaccgt cttgtcgaat atcaaaaact gttgcatcat
     7981 agtctttgct ggctgcattt atatattgaa ttcccattga ttcaagccaa ctaatatatt
     8041 ccctatttat ttcttgaccg ctatcatacg aaccaattgg tgaggaggaa gtttgaacaa
     8101 tcaaactcgg actcaaattt ttaatgaaat ccttggtatt tgatttgttg gtatcatggt
     8161 gatgattaaa cttcatcaaa tcaacttttc caatgagagg accatacttg tcttctgctc
     8221 catgaacatt atctaagtcg cccccaaggt aaattttctt gccattgact tttaccacac
     8281 taatcaagga attggaatta tcatcccaaa ttttctttaa ttcacctgat gaatcggttt
     8341 cattttcata gttatagagt tgaatatcca tgtccccaaa ctgaaaatga gcatcccctt
     8401 gtgtgatatt ttgaataact gaaacacctt tttctgaagc agtctgtaaa accttatcat
     8461 aaccgtacag attatcccat agacgttcag aattagtaat acgattatca ctatatttct
     8521 taagatagac tcggtcaact ggataggtag acagtaattc atcaacattt ccaatatgat
     8581 cactgtgggt atgggtcacc aaaataaaat caagtttttg gacacccaat tccttcaaac
     8641 gacgaaagac acggtctgtt agaacatgct tataagacgt ttcaatttct tctctccatg
     8701 gatagcgaga atcacttcca tctgggaaat cataatcttc tcctgtatcc accatggcaa
     8761 aatgtccatt gctttcaaga ataatcgcat cactgccacc ttcttgaaca ttgataaagt
     8821 ggattttatt tcctgaactt tcttgagcct gaacattccc ataccatgac aaacctaaaa
     8881 aagcgcctac aagtgctaaa ctagttaatt tctttttcat tcttactttc tcaatctctc
     8941 caaggtttcc ttaaaaatct ctgggatatc tgctttaaat tccaaggtct tacctgttct
     9001 cggatgagta aaacctaaag tcttggcatg aagaaattgt ccatgtcctt tcaaagtctt
     9061 gcgaggacca tagacctcat caccagcgac tggatggccg atataagcca tgtggacacg
     9121 gatttgatga gtgcgccctg tctccagttg caactctact aagctataat cgccaaagcg
     9181 ttccaagacg tgaaaacgcg tcactgcagg cttcccttta gcagttacag cctgtttctt
     9241 acggtctttt tcactccggc caatcggcgc ttcaattaca ccacgatcat taggcagatt
     9301 tccatgaaca atcgcccaat atttgcggag agacttttta tccttgagtt cttgggcaag
     9361 tgctagatgc gcatcatcgt ttttagcaat catgagaaga cctgacgtat ccttatcaat
     9421 acggtgaaca attcctggac gcagaacccc attgataccc gacaagtcct taatatgata
     9481 catgagggca tttactaggg ttccactggt atgaccagca ctcgggtgca caaccattcc
     9541 ctgaggtttg ttaacgacag ccacatcctc atcttggtag actatttcta gcggaagatc
     9601 ctcagccaca tactctaata cctctggttc tggcacatgg taagtgacga catcaccctc
     9661 ttggactgtg tatttagctt tcttgacttg accattgacc aagacctggc ctgatttaat
     9721 ttgttcattc gcaagactgc gtgataattc tgtcaaatct gacaaagcct tatccaaacg
     9781 cagaccacca gtttcaattt taatttccat ttatttcctc ttttagcatt gcaatcaata
     9841 aaataatcac tccaaccgtc agatagctat ctgccacatt gaaaattgca aagttgataa
     9901 agtcaaggtg gaacatatcc acaacaaagc cctgactggc cctgtcaata aagtttccaa
     9961 gaccacccgc gattatcaaa gtcaaaccca agaccatcca gaatgagtcc tccatgtgtt
    10021 tatgtaaata ccaaatggca cctatcacga caaccagagt aatgacagcg aataacagct
    10081 gctgatcttg taagatagaa aaggctgcac ctcgattttg caggtaggtc aagctaacga
    10141 aattgggaat ccaggagcgc acttcaccca gtggaatctg ctggacgata taggatttga
    10201 ccaactgatc cagcccaatt aaaagcagta caatgactgc cactattgct ctttttttca
    10261 tgatttcctc ttttgatcaa aatattcttg catgacttct acgaagagag tcccagcttg
    10321 actaagctcc acttcttcac gtttaacata gaccatgcgg ttatctaggt tatccttgag
    10381 acgaataact gtaatgccat taacactgtc actatctaaa aatccagaac ctgtcgcata
    10441 ggcgtccgtc cgctccaaaa taccattcaa ggtggcacgg tctgtcacat taaacatctg
    10501 tgagctagcg ctggtatcga caaagttctc tgaataataa aggtactcgt ctttctcttg
    10561 agtgaaacga accgttggta aatccgctaa atcctccatg actaattcct ctttccgagc
    10621 taaaggatga ccctcacaga gataaatatg ggtatggaaa ggaatcaatt cgatgacctc
    10681 cagacctaac ttttcaaccc gttgcataat ccccttttta ttttgattgt tgaggtagat
    10741 aatcccaatc tcactatgcc cttgcgccac ttcatctaat atttgaacag tagttgattc
    10801 aaaaatacgg aagttcttat agtcaggata gcgctctgaa aaggccgtaa tagttggtgg
    10861 taagaagtca tagtgctggc tagcaacgga aaattcatct ttttcttctt caggattggc
    10921 atactgattt tgaaaaatat caaatccttt aaccaattct tgcgcttttt cataaaattc
    10981 catcccacga cgggtcaaga aagtccctga gctggtccga cggaaaatct taaagcccaa
    11041 ctctttttcc aaatcacgaa cagaaataga cagactcggc tgactaacat acatcttttc
    11101 agcagcttca cgaaaagtac cactattggc aatagccaca acatagcgta attgttgaat
    11161 gttcatcttc tacccccaac ttctttatct ttttattata ccatatttta gaagttttcc
    11221 aaaaaggaaa aaagaacatc ctattcttct taactatctt cactatctgc ctttctcacg
    11281 ccaatcttat tttcaaaatc aattcaaaaa aataagtggc tacacaccac ttcagtatcg
    11341 gaaagaaaaa cgttgactat ttgtgaaaaa agaaaatgcc ggaaaattcc gacatttttt
    11401 agtaagctaa cttcctgaaa ataggagtaa ccaaacatcc cagaaagcag tgatattgat
    11461 gagaatatga actagtattg gatagtagat gtttttagtc atgcgataca atagagccaa
    11521 aataagacct ccgctagcat aaatgaaaaa agcaagagga gttaaagcaa aattgatatg
    11581 aatataaccg aaaataatag caaaaagcaa gacatctccg taccaaggcg agtttttgaa
    11641 aaaggttgtc ataagcacac cgcgataaat caattcctca gcaatagggc cgatgaagca
    11701 aacgatgagc aaaaaatagg gtaattcctg tctccctatc atttctatcg tttcattcaa
    11761 agaaatttga tttgaagaca gggatatgaa atacgaaaag agaaagtcag acatatacga
    11821 agtgatgtaa cccagtaaaa ggtagataaa atacctcagc tgccacttga aatgaaaagt
    11881 tttctttcct gcaaaaacta gtagatagat gaccgctaat aaaagaactc cactctccat
    11941 caaaagcaga atctgaaaaa attcacgact tgctggtaga tagggctttg cgagataatt
    12001 gaaaagcctc caaaaccaag ttgatttgta aaaaattaag gacaatgcta gtaaaatttg
    12061 aatagcccgt tttttcatat taaattctct gctttctcca cttgtttctt catattacta
    12121 ataaatttta cttaaaatct cgcagcactt cctttgcaaa gatgattacc tcctccaata
    12181 tatcctaaat catcggtgtc tctgggacaa aatccatgaa ccagcagagt taatactggt
    12241 tccattttcc aaggataata accattaggt tctttaccat agggatctgc tccaccttgt
    12301 atcagctcta attcttcatt tgttagattt atattttttg tcattaaaat catgatatat
    12361 ttcctccgtt attgtttaga ttagttgagt aatctgctac tcatacctac ttacaaaaaa
    12421 actattatat taagttggtt ttttaatttg tctagttgca acattgacaa acatagtata
    12481 gcatatcttt gccaaatatc ctcttcaaat catgaattgt catcaaaaca tcttaaacta
    12541 taaaatcaat tagtctcaag ctttctatca atttcttatc caaaatatgc tataataata
    12601 ccaaaagata aagaaggaag acctatgatt aaactactag ccttggatat ggacggcacc
    12661 ctcctcaatg aagccaagga aatcccacaa gctcacatta ctgctattca caaagccatt
    12721 gaaaaaggtg tcaaactggt tctctgtacg ggtcgccccc ttttcggtgt cctcccctac
    12781 tacaaaaaac tggggcttga cctccagaac gaatatgtta ttgttaacaa cggttgttca
    12841 actcaccaaa ccagtgattg gggtctagtt gactggaaag aactgagtcc agctgacatc
    12901 gaatacctct atgaccttgc tgaaaagagt gatgttcagt tgacactttt tgacgagtca
    12961 cattattttg ttctcggtgg caagcccaat caagttattg aaaatgatgc taaactagta
    13021 ttttcagacc tgactgaaat ttctcttgag gaagcgacta gtggaaagtt ccggatgttc
    13081 caaggtatgt ttttaggaac aaaagaacaa acagacgatt ttgagcagcg ttttgctgaa
    13141 gagctttgcc aacgattcag tggagttcgt tcgcagcctg tcatttatga agcaatgcca
    13201 cttggaacga caaaggctac tgctctttca cgactagctg agattttgaa gattgattcc
    13261 tcagagatta tggccatggg cgatgctaat aacgatatcg aaatgctcca gtttgcaggg
    13321 cttgggattg caatgggaaa tgccagcgat tatgtcaaat ctcttgcgga tgccgttacc
    13381 tcaagcaacg aagaagacgg cgttgcgcgt gctattgaga aatatattct ataaaaaaga
    13441 aaagcaaata gacagaagtt actgctattt gcttttttgc taatatttta aaatacggac
    13501 taatcaatag acaagaatag cgaatcataa aaatcgattt actagatgcc atagtatctt
    13561 atagttgcta ataagaagtt agtctagcag aatgaatctc tcatttctcc cacactaatc
    13621 tgtaatttgt ctatacattt ctggtcttct atctcgaaac aagccccagt ttagacgttc
    13681 acttgctccc ttgtctaggt cataagtagc taacagaaca gcttcttctt gtctttcagc
    13741 tcgttctaga atagctcctg tttcatccgt cataaaggag gaaccgtaga agtcaagact
    13801 ggaactctgt ccgccatttt cctcactagg agtaacctcc tctaaaccat aacgattggc
    13861 tgcgatgact ggaacaatat tcgctgctgc gtgcccttgc atagtacgtt gccagtgacc
    13921 acaactatct gtatccaaaa ttggctctga accgatagct gtaggataaa agagcaattc
    13981 agcaccattc aatgcaagac agcgcgctgt ttcagggaac cattgatccc aacagatacc
    14041 gataccaatc ttagcatagc gagtattcca gaccttgaaa ccagtgttac caggcgtgaa
    14101 atagaatttt tcttgataat aatggtcatc tggtatatgg gtctttcgat aaacgcccag
    14161 cacttcccca tctgcatcaa tgacggcaat agagttatac aagacattac catctttttc
    14221 atagaaactg attggtaaaa caacttgtag ttccttagca atcaccttaa aatgctgaat
    14281 ggcagtattt tccgctacag attgggcata ctggtagtag tcatactgac gttcctgaca
    14341 gaaataggga tgttcaaaca actcgggcaa gagaataatt tgggctcctt gctcagcagc
    14401 ctgacgtact aaacgctctg cggtttggat atttgttgcc acatccttag cgcattgcat
    14461 ctgaatggtt gcaactctta catttctcat ctttttctcc tattctggaa tttgttgggt
    14521 gatacagtgg atattgccac cacctaagag aatatctctg gctggtattc cgacaacttt
    14581 acggtctggg aaacacttgc tgaggatatc taaggccact tggtcgttta catcctcaaa
    14641 ctgtggaacc aagacagcct tgttggcgat ataaaagttt acgtaggaag ctgctagtcg
    14701 ttcacctgcg tatcgctctt cttctccttc ttcatagatg tagcctggca aatcttcttc
    14761 tgtcacaact tgtcgaactg cagggatagg caatttatga atggtgaagt gacaaccttt
    14821 tgcatctgtt tcctgttcta agagttcgag atctgctttt gacatggcat actggggatc
    14881 attttcgtca tctgtccaag ccaaaacaac ctcagcagga ccaacaaagg cagcaacatt
    14941 atcgacgtgt tcattggttt catcctgata aataccataa ggaagccaaa taactttttc
    15001 agcaccaaga ctttctaata atgtgttttc aatctcctct ttagtcaagt taggattgcg
    15061 accaggacta agcaagcaac tttcagttac gagaatagtt ccttgaccat cgctatggat
    15121 tgcgcctcct tccagtacaa aaggtttagc atcatagaca ggcctttcca aggcctcagc
    15181 aaaacgactg gctacttggt catcctcttc ataatcttga taaagaccat cataggtgcc
    15241 tccccaagca ttgaaggccc aatccacggc taatttctta cctttgtcat tgacgagaat
    15301 ggttgggcca gtatcacgcg cccaggcatc attggtggga atgtctaaat aaacaacctt
    15361 gtctccaaga taggattggg cttcagatag ataggcctgc tccaccaaaa gatagactct
    15421 ttccccttct gctatagtct cgatgatctg agtaaatgct cttttagcat cctttccttg
    15481 aaaaggccat gatcctggtc gagtcggcca tatcatgagg gtaccatgat ggggttcgta
    15541 ctctgctggc atgtgatagc ctaatttttt tggactgtcc atcatgataa tctcccttta
    15601 aagtcttgat agccaaaagc tttgagtaag ctacagtctc cctgttcgtc catgagatag
    15661 agacttggca atccaatacc attaaaggta ttatttttga caaaagaata aatggccatg
    15721 tcttgaaaat aaagtctgtc tccgatttgg actggatttt caaaactata atcaccaatc
    15781 acatcgcccg tcagacaggt attagaagaa agtctgtagg tatgggcttt ttcctgtgcc
    15841 tcaaagccat ttctcaaagg tggacgatag ggcatctcaa gtacatcagg catatggcag
    15901 gtcgcagagg cgtctaaaac caagatttcc ataccgtttt ctacaatatc taatacctca
    15961 gttgctaaat aacccgcatt aagcgcaatg gcttcaccag gctcgatata gatttcaaga
    16021 ttgtaagttt ttcggatacg cttgatttct gaaatcagca aatccacatc gtaaccttct
    16081 cttgtaatat gatgaccacc acccatattg agccatttta cctcatgtaa gtagggacca
    16141 aactgttctt ctactgcttt caaagttgtt tgtaaatcat ctgctccctg ctcgcaaagg
    16201 gtatgaaaat gaagtccgtc aaccaaatct agcaaatcac tcggaatctt gtctatagta
    16261 actccaaagc gagaacctgg tgcacaaggg tcatagagcg cgtgatctcc ttgagttgaa
    16321 cactgagggt tgaggcgcaa accaacactg acaccagcct ctcgacaacg cgaaccatgc
    16381 ttacgcaact gtctctctga gttaaagacg atatggtctg ttatcccaag caattcctcc
    16441 atgtcctcat ccttgaaagc tggtgcaaaa acatggactt caccaggaaa ttcttccctt
    16501 gccaatttgg cctcatagag tccactagct gtcgtacctg atagatactg gctaatcaag
    16561 ggataagttt tgtagaggga atatgccttc tgggcaagca agaccttgca accggcctct
    16621 tcttgtacat attgtagaat gcggcaatta gcttctaact tggccaagtc aataacatag
    16681 gctggtgttg gtacttgttc taacttcatt agtccaccat ttgtggattt tcaaccacaa
    16741 cccatggcaa accatactca ttcaaagctt ccatgaatgg atctggatct aactcctcaa
    16801 ggttatacac tccagcttgt ttccaagttc cgttcatgac taattttgtc ccaatcatgg
    16861 ctggaactcc tgtcgtataa gaaatagctt gcgaaccaac ctctgcgtaa cattcctgat
    16921 ggtcgcagac attgtagata tagatagtct ttttgacacc gtctttgaca cctgtaaaga
    16981 tacatccaat attggtttta cctacagtac gtggaccaag gctagcagga tctggaagca
    17041 aggctttcaa aaattgaatt ggaacaattt cttggccgtt aaagttaatg gtatccgtac
    17101 gaaggagtcc aacattttca agacatttca tgtgcgtcaa gtaagattga ccaaaagtca
    17161 taaagaaacg aatgcgtttg acacctggaa tgttcttggc caatgattcg atttcttcat
    17221 ggtgaaggag atacatatct ttttgtccaa cttgagggaa atcatactca cgcttgatag
    17281 acatagcttc gacttcgacc catttcccat cttcccagta agaacctggc gcagaaacct
    17341 cacggagatt aatttctgga ttaaagttgg ttgcaaatgg ataaccgtgg tcaccgccat
    17401 tacagtctaa aatgtcgata taatggattt catcaaaata gtgtttgagg gcataagctg
    17461 aaaagacact agttacacct gggtcaaaac cagaaccaag aagagcagtc aagcctgctt
    17521 ctttgaattt ctcttgataa gcccactgcc atgagtagtc aaagtaggct gtaaaaccaa
    17581 gttccttaca acgtttttcg tagatagcac gccactcagg gtcttctgtg tcttctgctt
    17641 cgtagttggc tgtatcgata tagtgaacac ctgttgccaa acaagcatcc ataatggtta
    17701 aatcttgata aggcagagct acattcaaaa cagcttctgg tttgtagctt tcaatcagag
    17761 caatcacttc ttcaaccttg tcagcatcaa gagcagctgt ctcaatcttt gtacttgttt
    17821 tgccttccag tttagctttc aagtcatcgc attttgactt ggtacggcta gcaatcataa
    17881 tctctgtaaa tgtttcgcta tcttgacaaa tctttgaaat agcaacttgg gcaacgcccc
    17941 cacaaccaat aactagtaaa cgactcattt ttttccttcc tcttcttcta aaatgtcctc
    18001 aacatacttg ggcaacataa aggctcccac gtgtaagttt gcagtgtagt attctgtgaa
    18061 aagctggcgt tttttccagc cttccttgtc aaaatctttg acagggtggt attttttcga
    18121 tgcaaatcca aacaaccaat agccagctgg gctagttgga atatgggcct gataaacccg
    18181 actgattgga aaggcttgat tgaccttgcg gtgcatgctt cggcaggccg actcatcctc
    18241 gtcaaagaac ggactcccat gctggtaaat catgatgccg tcttccttca gagctcgata
    18301 actattgccg tagaattcct tggtaaagag tccttccgta tggccaaatg gatctgtcgc
    18361 atcgttgatg ataatatcat agtcatattc gcagtttcgc aaaaagcgta gcccattttg
    18421 gtagtaaatg gtaacacgag gatcatctag gcctgcagca aagtctggga aatactcacg
    18481 acagacctcg accaacatct catccggttc cacgatatcg atttgttcca gttcaggata
    18541 gagtgttaat acttgggcaa caccgccgtc accaccccca ataaccaata ctttctttgg
    18601 atttgggtgg acagccatgg gaacgtgaac ggtcatttca ttgtagacga aatcatccgc
    18661 atctgagaac aagacatggc catttaaaat cagtattttc ccaaaagctg gcgtatccaa
    18721 gacttcgata tcctgccatt cactttttcc agcgtaaagt tgcttggctg ttctcagaga
    18781 caatttgaca tctggagtat gaacttcaga aaaccataaa tccatctatt tctccttata
    18841 ttatatttag cgcagttagc tactgccaaa gcccaagtgg tatacttgga ataagccact
    18901 gtggattagt tcatttcctc caatcgcttg acgatttccg aaagggtcta accacagctt
    18961 tttgtttcaa ttggtaatga gtttgataac gcatagacgt tttatctcgt ctaaggtaac
    19021 aaggcaaaaa gttcgtggat aaccaagtag acttgaaata ctatatctgg aggtactccc
    19081 atgctttatg tgggcattga tgtcgctaaa aataaacacg atgttacagc cttgaatgtt
    19141 cgaggaaaac tgttcttaaa ccactcactt tttcaaataa taaagctggt tttgaactct
    19201 tagatctgtc tcttcgacaa ctcaaccaag actgtctcat cgctct
//
LOCUS       DBERDS010000039        18973 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.039, whole genome shotgun sequence.
ACCESSION   DBERDS010000039 DBERDS010000000
VERSION     DBERDS010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.039"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            147..449
                     /locus_tag="ACL73E_001528"
     CDS             147..449
                     /locus_tag="ACL73E_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGS0801478.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAVAGKTSEAWIWTKFGEQVSFFYDYDD"
     gene            520..2541
                     /locus_tag="ACL73E_001529"
                     /pseudo
     CDS             520..2541
                     /locus_tag="ACL73E_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            2543..3184
                     /locus_tag="ACL73E_001530"
     CDS             2543..3184
                     /locus_tag="ACL73E_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801479.1"
                     /translation="MIELKNISKKFGSRQLFSDMNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3288..4640
                     /gene="murD"
                     /locus_tag="ACL73E_001531"
     CDS             3288..4640
                     /gene="murD"
                     /locus_tag="ACL73E_001531"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGS0801480.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGEHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4644..5702
                     /locus_tag="ACL73E_001532"
     CDS             4644..5702
                     /locus_tag="ACL73E_001532"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGS0801481.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5712..6941
                     /gene="divIB"
                     /locus_tag="ACL73E_001533"
     CDS             5712..6941
                     /gene="divIB"
                     /locus_tag="ACL73E_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGS0801482.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEIEE
                     SESKEKEEQDKKLAKKAIKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYAT
                     MKDIRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQF
                     PTKFTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIK
                     AFVSELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSK
                     IKPQLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKK
                     QEEESNRNQTTQRSSRR"
     gene            7174..7875
                     /gene="pyrF"
                     /locus_tag="ACL73E_001534"
     CDS             7174..7875
                     /gene="pyrF"
                     /locus_tag="ACL73E_001534"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGS0801483.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            7909..8541
                     /gene="pyrE"
                     /locus_tag="ACL73E_001535"
     CDS             7909..8541
                     /gene="pyrE"
                     /locus_tag="ACL73E_001535"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGS0801484.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            9002..9124
                     /locus_tag="ACL73E_001536"
     CDS             9002..9124
                     /locus_tag="ACL73E_001536"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801485.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            9220..9984
                     /locus_tag="ACL73E_001537"
     CDS             9220..9984
                     /locus_tag="ACL73E_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801486.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFLAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9984..10736
                     /locus_tag="ACL73E_001538"
     CDS             9984..10736
                     /locus_tag="ACL73E_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801487.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTAILFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLALLSIIIPLTVFSVHRNWRRV"
     gene            10746..11444
                     /locus_tag="ACL73E_001539"
     CDS             10746..11444
                     /locus_tag="ACL73E_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801488.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11441..12088
                     /locus_tag="ACL73E_001540"
     CDS             11441..12088
                     /locus_tag="ACL73E_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801489.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12175..13041)
                     /locus_tag="ACL73E_001541"
     CDS             complement(12175..13041)
                     /locus_tag="ACL73E_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0801490.1"
                     /translation="MKLFKPLLTVLVLAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKLFGYVDNDGSYQGYDIELGNQLAQNLGVKVKYISVDAANRA
                     EYLISNKVDIILANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDTAK
                     ADDLVVEGGKVD"
     gene            complement(13053..13772)
                     /locus_tag="ACL73E_001542"
     CDS             complement(13053..13772)
                     /locus_tag="ACL73E_001542"
                     /inference="COORDINATES: protein motif:HMM:NF014516.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0801491.1"
                     /translation="MLRIQSHPQRTFSRNQKREVVVILGPSGCGKSTLLRCLNGLESI
                     QGGDIFLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNLILGPIKTQGRDKK
                     EVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPEIILFDEVTASLDP
                     EMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKIAEEGTAQAFFTNP
                     QTKRAQEFLNVFDFSQFGSYL"
     gene            complement(13811..14488)
                     /locus_tag="ACL73E_001543"
     CDS             complement(13811..14488)
                     /locus_tag="ACL73E_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0801492.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFRTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(14448..15128)
                     /locus_tag="ACL73E_001544"
     CDS             complement(14448..15128)
                     /locus_tag="ACL73E_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0801493.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            15343..15477
                     /locus_tag="ACL73E_001545"
                     /pseudo
     CDS             15343..15477
                     /locus_tag="ACL73E_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            15617..17107
                     /gene="lysS"
                     /locus_tag="ACL73E_001546"
     CDS             15617..17107
                     /gene="lysS"
                     /locus_tag="ACL73E_001546"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGS0801494.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALCEQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKVIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            17731..18867
                     /gene="lctO"
                     /locus_tag="ACL73E_001547"
     CDS             17731..18867
                     /gene="lctO"
                     /locus_tag="ACL73E_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGS0801495.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
BASE COUNT         5729 a         3366 c         4093 g         5785 t
ORIGIN      
        1 tctaaaaaat tcgatttttt ccttgacaac aaataataaa aatattattc ttatcacata
       61 agaaagcggt ttcaataaaa gagagaggag gatttatttt gttgcattgt tgctcagggt
      121 gtgctttttt tgaaagaaaa aataaaatga aaacgaaaaa acatagatta cttgctctag
      181 ctcttatttc aagttttaca ttattgggag ctgcatcagc tgctgtacaa tatccagatg
      241 gaggagtatg gacatatgga gaaggttcag gaggtggttg ggctttttca aattactatc
      301 atggtaaaaa atatcattat tcatccatcg tgagcagatg ggatggtcat tctgataaag
      361 gagaagcagt tgcaggaaaa acttcagagg cttggatttg gactaaattt ggggaacaag
      421 tatcattttt ctatgactat gacgactaat atttagtttt cttagataat tccccttgta
      481 agaaattaca gggggaattt tgtttacaag gagtctacta tgaagaaact attcatatta
      541 ttatcaactt tttttctcag cttcttcctt gcttggatta ttgtcttacg tgcgccacaa
      601 tatttatatg caagctatga ttccgtttct ttacttcgtg tcaaaaaaga tactcaggaa
      661 ccgacgcgtg aggtatttga acaggaattg gagaattttg caaactcaga acagagttta
      721 atagctagaa gaattgtaga gccgagtaag gatgggacga ctcactttac ttatgcaact
      781 tatggtcagg gaactttacc aaaagaattc caagaagcta gccaagaaag tcgtgaacgt
      841 agtgatccgc taaatagtta tctccttttg tcaggctcct tgacgaaaga aaagcttgcc
      901 gataaattag gagatttggg ttataaagca agtgctgacc gaaagatacc gccctatttt
      961 cttgcttttc gaatattact aaatcccctt attttaatta gtttagcaat atttggctta
     1021 tctttctttg ctttagtgat tatcactcgg attaaggaaa tgagagcagc aggtataaaa
     1081 ctcttttctg gtcagactct cttatccatc atgggggatt ctttatctac tgatatcaag
     1141 tggctccttc tatcagccct cctttccttc ctaggtgggg gagtcgttct ttttagtcaa
     1201 ggtttgtttt atcctatctt gttagccacc tatggttttg ggattagttt ctatctgttg
     1261 tttttattgg cgatttcaat tttactaatg cttctttatc taatgagttt gagttacaaa
     1321 gcattagttc ccgttattaa ggggagatta ccccttaaac gcctgatgat tttaacccta
     1381 ttgtgtcagt tggttgctgt ctttacagta ggatacgctg ttaagacagg tttgacgtct
     1441 taccaacgat tgaaagaact tgaaatttca aaacaagcat ggcaggatag agcagactat
     1501 tatcaaattt cttttggctt aggtgataga ggaaaagata cagaaaatca gagcaagtga
     1561 tatgcctttg ccaaggaagc aatcgaagaa gaacaagctc tttatgtaaa ggataatctg
     1621 ctccattttg ccaatccaca aggaaaaaat gaacagggag agacactgga tacctatagt
     1681 ccagatgcta atacgctcta tgttagtccc agttatttgg acaaggaaaa ggtcgtggta
     1741 gatgctgaga ccaaacagaa gttagcccat cttcaaaaag gtgagtttat cctcttgctc
     1801 ccagaacatt tgcgctctcg agaagcagaa cttaagaaag tttttgaaga aagattgagt
     1861 tattatggaa aatctggtga ggaggcaagt gctcctttgg attatgagat gaaagcgcac
     1921 gttagttatc tttcaatggg agaaaagcgg tttgtttata ataacggtga gaatcccgta
     1981 tccactcagt atttgactga tccgatttta gtggtattca cgccgacttc tacaggtgat
     2041 agttttatat ccttatctag ttggtctatc aatgctggaa aacaactctt tatcaaagga
     2101 tatgagagtg ggctagaact cttgaagaaa gctggaattt atgagcaagt atcctatctt
     2161 aaagaaggaa gaagtgttta tctaactcgt tataatgaag ttcaaactga aacagcaact
     2221 ttaatcttag gagctattgt tggaatagcc agttccttgt tactctttta ttctgtcaat
     2281 cttctatatt tcgagcaatt ccgccgagat atcttgatta aacgaatttc aggtttacga
     2341 ttttttgaaa cacatgctca gtatatggtt agccaatttg ccagttttgt atttggtgct
     2401 agtctcttta ttttaagcag tcgagacttg gtgattggct tgctcacttt attggtcttt
     2461 ctagctagtg cagttttgac gctttaccgt caagcgcaga aagaatctcg tgtttctatg
     2521 acaattatga aaggaaaata ggatgattga actaaagaat atatctaaaa aatttggaag
     2581 ccgtcagcta ttttcagata tgaatcttca ttttgaaggt gggaaaattt atgccttaat
     2641 cggtacaagt ggctgtggta agacaacact cttgaatatg attggacgat tagagccata
     2701 tgacaaaggg caaatcatat atgatggcac ttctcttaag gacattaagc cttctgtttt
     2761 ctttagagat tacttaggat acttatttca agattttggc ttaattgaaa gccaaaccgt
     2821 caaagagaat ctcaatctgg gtttagttgg taaaaagttg aaggaaaaag agaaaatctc
     2881 tttgatgaaa caagctctaa accgtgtaaa cctctcttat ttggatttga agcaacctat
     2941 atttgagtta tcaggaggag aagcacaacg tgttgcacta gcgaagataa ttttaaagga
     3001 tccacctttg atcctcgcag atgaaccaac cgcttcctta gaccccaaaa actctgagga
     3061 attactttcc atcctagaat ctttaaaaaa tccgaatcgg accattatta ttgcgaccca
     3121 taatcctctg atttgggagc aagtggatca ggtcattcga gttaccgatt tatcacatag
     3181 atgatatggt aagattcagt tagaagaaag agtcacaaac acactttgtg gcttttttat
     3241 ttccataaaa atggtaaaat agtaggagta gaaatggagt tcgagacatg aaagtaatag
     3301 atcaatttaa aaataagaaa gtccttgttt taggtttggc caagtctggt gaatctgcag
     3361 ctcgtttgtt ggacaagcta ggtgccattg tgacagtaaa tgatgggaaa cctttcgagg
     3421 acaatccagc tgcccaaagt ttgctggaag aagggatcaa ggtcattaca ggtggccatc
     3481 ctttggaact cttggatgaa gagtttgccc ttatggtgaa aaatccaggt atcccctaca
     3541 acaatcccat gattgaaaag gctttggcca agggaattcc agtcttgact gaggtggaat
     3601 tggcttattt gatttcagaa gcaccgatta ttggtatcac aggatcgaac ggtaagacaa
     3661 ccacaacgac tatgattggg gaagttttga ctgctgctgg ggaacatggt cttttatcag
     3721 ggaatatcgg ctatccagct agtcaggttg ctcaaatagc atcagataag gacacgcttg
     3781 ttatggaact ttcttctttc caactcatgg gtgttcaaga attccatcca gagattgcgg
     3841 ttattaccaa cctcatgcca actcatatcg actaccatgg gtcattttcg gaatatgtag
     3901 cagccaagtg gaatatccag aacaagatga cagcagctga tttccttgtc ttgaacttta
     3961 atcaagactt ggcaaaagac ttggcttcca agacagaagc cactgttgta ccattttcaa
     4021 cacttgaaaa ggttgatgga gcttatctgg aagatggtca actctacttc cgtggtgaag
     4081 tagtcatggc agcgaatgaa atcggtgttc caggtagcca caatgtggaa aatgcccttg
     4141 cgactattgc tgtagccaag cttcgtggtg tggacaatca aaccatcaag gaaactcttt
     4201 cagccttcgg tggtgtcaaa caccgtctcc agtttgtgga tgacatcaag ggtgttaaat
     4261 tctataacga cagtaaatca actaatatct tggctactca aaaagccttg tcaggatttg
     4321 acaacagcaa ggtcgtcttg attgcaggtg gtttggaccg tggcaatgag tttgacgaat
     4381 tggtgccaga cattactgga ctcaagaaga tggtcatcct gggtcaatct gcagaacgtg
     4441 tcaaacgggc agcagacaag gctggtgtcg cttatgtgga ggcgacagat attgcagatg
     4501 cgacccgcaa ggcctatgag cttgcgactc aaggagatgt ggttcttctt agtcctgcca
     4561 atgccagctg ggatatgtat gctaactttg aagtacgtgg cgacctcttt atcgacacag
     4621 tagcggagtt aaaagaataa aatatgaaaa aaattgtctt tacaggtggg gggacggttg
     4681 gacacgttac cctcaatctt ttgttaatgc ccaagttcat cgaagatggt tgggaagtcc
     4741 actatatcgg ggacaagcgt ggtatcgaac accaagaaat ccttaagtca ggtttggatg
     4801 tcactttcca ctccattgcg actgggaaat tgcgtcgcta tttctcttgg caaaatatgc
     4861 tggacgtctt caaagttggc tggggaatcg tccaatcgct ctttatcatg ttgcgacttc
     4921 gtccacagac ccttttttca aagggaggct ttgtctcagt accgcctgtt atcgctgcgc
     4981 gtgtgtcagg agtgcctgtc tttattcacg aatctgacct gtctatgggc ttggccaata
     5041 aaatcgccta taaatttgcg actaagatgt attcaacctt tgaacaagct tcgagtttgg
     5101 ctaaggtcga gcatgtggga gcggtgacca aggtttcgga caaaaacact ccagaaccag
     5161 atgaattggt ggatattcaa acccacttta atcccaaatt gccaactgta ttgtttgtcg
     5221 gcggttctgc aggcgctcgt gtctttaacc aattggtgac agaccataag aaagaactaa
     5281 cagagcgcta caatattatc aatttaactg gagattctag cctgaatgag ttgaggcaaa
     5341 atctttttcg tgttgactat gtgaccgatc tctatcaacc cttgatggaa ttggctgata
     5401 ttgttgtgac acgaggtggt gccaatacga tttttgagct cttggcgata gcaaaattgc
     5461 atgtcattgt gccgcttggt cgtgaagcta gtcgtggtga ccagattgaa aatgcagctt
     5521 actttgtaaa aaaaggctat gcagaagacc ttcaagaaag cgatttgacc ttggatagtt
     5581 tggaagagaa gctttctcac ttactaagtc acaaggaaga ttaccaagct aagatgaaag
     5641 cttctaagga attgaaatct ctagcagatt tttatcaatt gttgaaaaaa gatttatcat
     5701 aaggaaagta aatgtcaaaa gataagaaaa atgaggacaa agaaatcctc gaagaattga
     5761 aagagttatc agaatggcag aaacgaaacc aagaatatct aaaaaagaag gctgaagaag
     5821 aggcggctct agctgaggag aaggaaaagg aaagacaagc tcgaatggga gaagaatctg
     5881 agaagtcaga ggataaacag gaccaggaga gtgaaacaga ccaggaagat tcagaatcag
     5941 ctaaggaaga gtctgaagaa aaagtggcat cctcagaggc tgacaaagag aaagaagaaa
     6001 aagaagagat agaagaatca gagtctaaag agaaggagga acaggataaa aagcttgcta
     6061 aaaaggctat aaaggaaaaa ccagccaaag caaagattcc tggtatccat atcttgcgag
     6121 ccttcacgat tttatttcca agtctgcttt tattgattgt ctctgcctac ttgctcagtc
     6181 cttatgcgac catgaaagat attcgtgttg agggaacggt gcaaactaca gctgatgata
     6241 ttcgacaggc ttcaggcatt caggattcgg attatacgat taaccttctg ctagacaagg
     6301 caaaatatga aaagcagatt aagtctaact attgggttga atcagctcaa cttgtctatc
     6361 aatttccaac taagttcact attaaggtca aggaatatga tattgtggcc tactatattt
     6421 ctggtgaaaa tcattatcct attctttcca gtggtcagct tgagactagt tctgtgagcc
     6481 tgaacagttt accagaaact tatttatcag ttctctttaa tgatagtgaa caaatcaagg
     6541 cttttgtctc agaacttgct caaattagcc cagaactcaa ggcggctatc caaaaggtgg
     6601 aattagcccc aagcaaggtg acatccgatt taattcgatt gaccatgaat gattcggacg
     6661 aagtcttggt tcctctatct gaaatgagta agaaactgcc atattacagt aagattaagc
     6721 ctcaattgtc agaaccgagt gtggtcgaca tggaagctgg aatctacagc tacactgtgg
     6781 cggataaatt aattatggag gctgaggaaa aagccaaaca agaggccaag gaagctgaga
     6841 aaaaacagga agaagaacag aaacgtttag aagaagaaca gaaaaaacaa gaggaagaga
     6901 gcaatcgaaa ccaaacgacc cagcgctcat cgcgtcgcta ggtttacctt ttctcttata
     6961 gttctttagt gaccatgttt ttacttgaca agtgctagta gaaataatag aatagtaaaa
     7021 aacctttaaa gcagtccaga gaggcagcta aggttagacg gtgaaagggt ggagactacc
     7081 catttttcgt ggaaccttgc tgttggcagg ttcctttttt cgtggcttct gttggccaga
     7141 ctctctcact agtaaaggta aaaggagaaa cctatgcgag aacatcgtcc aatcattgct
     7201 cttgattttc ctagttttga ggcggtcaag gaatttttag ctcttttccc agcagaagaa
     7261 agcctttatc tcaaggtagg gatggagctt tattacgcag cggggcctga gattgtgtcc
     7321 tacttaaaag gtttgggtca tagtgtcttt ttggatctca aacttcatga cattcctaat
     7381 acagtcaagt cagccatgaa ggtcttgtct cagcttggtg tcgatatgac taatgtccat
     7441 gcggctggtg gtgtagagat gatgaaggcg gcgcgtgaag gtcttgggag tcaagccaaa
     7501 ttgatcgctg taacgcagct gacatcaacg tcagaagccc agatgcagga gtttcaaaat
     7561 atccaaacca gtctgcaaga gtctgtgatt cactatgcca agaagacagc tgaagctggc
     7621 ttggatggtg ttgtttgctc ggctcaggaa gtacaagtca tcaagcaggc taccaatcca
     7681 gattttatct gtctgacacc agggattcgt ccagctggtg ttgcagttgg agatcaaaaa
     7741 cgagtcatga cacctgctga tgcctatcaa atcggcagtg actatatcgt agtgggacgt
     7801 cccattaccc aagctgagga tcctgttgca gcttatcatg ccatcaagga tgaatggaca
     7861 caggactgga attaaagaac tagattagaa aaataaaagg agaataccat gacacttgct
     7921 aaagatatcg ctagccacct cttgaaaatc caagccgttt acctcaaacc agaggaaccc
     7981 ttcacttggg catctggtat caagtcaccg atttacactg ataatcgtgt gacactagcc
     8041 tatccagaaa ctcgtaccct aattgaaaat ggttttgtgg aagctatcaa agaagccttt
     8101 cctgaagtag aagtgattgc aggaactgca acagcaggga ttccacacgg agccattatt
     8161 gctgataaga tggacttgcc ttttgcctac atccgtagca aaccaaaaga ccacggagct
     8221 ggtaatcaaa tcgaaggtcg cgtagctcaa ggtcaaaaaa tggtagtggt tgaagacctt
     8281 atttcaacgg gtggttcagt tcttgaagct gtagcagcag ccaagcgaga aggagcagat
     8341 gtacttggag ttgtagcgat tttcagctac caattgccaa aagcagataa gaactttgca
     8401 gatgctggtg ttaaacttgt gacgctttca aactatagcg agcttatcca tctagcccaa
     8461 gaagaaggtt acatcacgcc agagggcctt gatcttctaa aacgctttaa agaagaccaa
     8521 gaaaattggc aagaaggtta ggtcagtaag ataaagagag acgaggctac cgagtctctt
     8581 ttaccatttt atttaaaata tgacaatatt ttaaataaaa taattgacaa cgctttcttt
     8641 tattgatata atgaaaatgt aatatgtatc aaattgatca atcaactatc ttgtttatca
     8701 cttcttaaga ggacgatgtc atgaaaagaa gaaaaatata ttcctttttt gcgtagttac
     8761 aattgcatct agtttgtttc tccctacagt tttagctaga cagattggaa attatgattt
     8821 aacgttgccg cgttggggtt cggatacaac tagtgagctt gagaaagaaa acgcctctgc
     8881 tggaattaat aatagtgaca gcactggtgg cggtaaaagg ttaagtacct ctattcgtag
     8941 cgcctatagt gggtcagata ttaccccggt atattcattg gggtctggct ctaggattgt
     9001 catgtactat aatggaggtg gtgacaatta tattggttct ggtactagat tagctatggc
     9061 gccacaattt ggaaatcatg taagaattca tacttcaggt tcttggagtc cagattctta
     9121 ttaacttact tgtcagagta agccttaaag atggttgatt gtgggtgtag catgaaaaaa
     9181 gaatgctaca ccctattttt attataagga ggagtaagga tggaattttt catttgtaat
     9241 cttgtacgag tcgttcaatc acctcgattt tatatgtctt tatttttgac ccttctttgc
     9301 atgagtttag gaaatttcct tgctttcaat ggtatttata aaattgaagg tttatcgatt
     9361 ttttttgccg cttcttctat tcgaggattt tcaccgatta gcctagtagc tgcacttatc
     9421 tgtacactgc cctattctag tcagataata gaggatgctg agagtcattt tctaacagca
     9481 caattgtgcc gaatttctaa aaagaggtat ctagctattg taggtagtac tgcaattatt
     9541 tcttcttttc tagtcttttt tctcccctat ttattattat taggaattaa tcttttagtg
     9601 actccttatc aggaaattta tattggagat tatagtggtg ccttaaaaga attatttgat
     9661 tctaatcagt tgctctatag tcttgtgacg actctctggt atggagtttg gggcgctgtg
     9721 ttctctattt ttggactagc tagtgctttg ctagtgaaga aaaaaatagg agctattttc
     9781 atcccagttg cctatatgat ggttggtggt atttttttgg ctattttagg gctatcttac
     9841 ttagaacctg tgacaacatt agctttggga tatcagaaag atatcagtct ttccttagtt
     9901 agtgggcatc ttgcttttat tttatttgtt agttgtttgg ttgtttatgg tacatttttt
     9961 ctacattcag aggactatgt ataatgaaac aatttgttca attttataaa aaagatttct
    10021 tagcagtatt ggtttatttt atattactgc tatcctgtgt tttatctagt acagtatatt
    10081 tattgcgctg tcgccaatat tcaatccatc caaatgtatt agaatggatc ttagttttac
    10141 ttcaagatat gacgactgga gtatattgct ttccgttcac atatatattg ttcttttttt
    10201 atttgatgaa taactatttt aataggttgg agtgtcgcat tcgtctgaaa tcaattaagc
    10261 actttaccag ttttagtttc aaattagcag ctcttagtac ggggatttgg acggcgattt
    10321 tatttttatt gatttttcta attgcattta gtaatggttt tagcttctct ttggagataa
    10381 aggaggttga ttttttaaga gaattttatg gcataagtat tgcaaacaat gctagtttct
    10441 ttataggatt ttttttctct tatatagcat actatttctt tttatcctta cttactatta
    10501 gcagtttttc ttggtttaaa aaatcaaaca tgagcttagt atttctgttt acttttttat
    10561 ttgtagaatc cttattctgg atttatcagt tgaacaatgg gataattgga ttattgccaa
    10621 tttttcagta tatggtaaat tccaatccgt atgcattgat ttattggctt gcattactat
    10681 ctatcataat tccattgact gtattttctg ttcatagaaa ctggaggaga gtgtaaaagt
    10741 tggaaatggg aaagttaagt agtcacatgt ggaggttgaa tcagataatc tataccaagt
    10801 acttttgggg ttatgttctt ttttggatat tgatttgttt aggattatgg tattggttag
    10861 aaggaaatga tagacttgtt atagaaattt taaaagggcc taatctgagt caaaactctt
    10921 ttttagtctt atctatatgg ttgcttcatt ggtttattat tcatacattt tttctagcag
    10981 ttgtatatcg tagaagagca tccgatttct ttctggaagt gattcgattt tcttctatta
    11041 agctctggat taggtatcag atttggacct gttttcttta tggacttatt ttaatcatgg
    11101 taaaagttct agtgattcaa tttatgttac agttaccaaa ctgggatata ggagttttgt
    11161 ttatagttga ttctttgaat gcttgtgtgc tatccttgct ttgctttatg ttatacgcac
    11221 taggagcgaa tgtacaaatg aactttgctt gcgttagttt ctttttactc atgattgtgt
    11281 ttggtggtct atttgtagga aatcgaacta attatctatt ttatattttg aatcgaggga
    11341 atggagatat aggacgagat ttatttcttc agttgctatt tttagtcttt ctttttaaaa
    11401 gcattttcta tttcactcgt caaaagagga ggtttataga atgaatgaaa taattacatt
    11461 aaaaaatatt gagttgaaat taaaaaaaac atgtgttttt caaaacctta attttagttg
    11521 taaacagggg gaaattatag gaattactgg tgcgaatggc tcaggtaaaa gtgtattgtt
    11581 taaattaata gctggtttat atagtccgtc ttatggagaa gtgttaatca atggggaaaa
    11641 tattgttcct gagagaaaaa ttccagctaa tttgggagct ttgattgaag aacctggttt
    11701 tataaattat tatagtggct ttaagaattt acaatatttg gcaagcatac gaggagtagt
    11761 tggtaatcag gaaatcaatg atacactgaa aatagttggt ctatatgagc aaaaagacca
    11821 gaaagttaaa acttattcgc taggtatgag gaaaaagcta gggattgctc aagcaattat
    11881 ggagaatccc tctattcttt tactagatga acctatgaat gccttggata aatcaagtgt
    11941 agaaaatatg agaacattgt ttagaaagct ctctagtgaa aaagggacaa caattttgat
    12001 tgctagtcat agtgaagagg atattcgtat cttatgtgat aaagtatatg caatagaaga
    12061 taaagtatgt acactgtgtt cagattgaac atcttagata gactcaggat gttataggta
    12121 aaatcttaaa aagggattgg agcttaaaat ccagttcctt ttaagagtta atgactaatc
    12181 aacttttcca ccttcaacaa ccaggtcatc tgctttagca gtgtcaccgt aggttgggtg
    12241 aagtgttttt tcataggcct tgtggaagaa gttttccttg cctaattttt caatatcttt
    12301 attgatgaag tctagcaatt cttggttgcc tttttgaact gctgccgcaa tggtatcggg
    12361 atcaccgagg gaagtaattc ctacttcaaa tcctttattt tcaagcgccc aagctagaac
    12421 ttccgtatta tcagttgaaa aggcatctcc acgtccgtca agaagagctt ggtaagagtc
    12481 actgtattgg tcgtattttt ggagtttgat ttctggatga ttcttttcaa aataagtctc
    12541 agcagtcgtt ccttttgtga caattaaggt tttaccttca agttgtttga cgtctgtaat
    12601 gagaccagtc ttaggtgata cgacacccag agaaactttc atatatggaa gggcaaaatc
    12661 aacttgtttc ttacgttcgt cagttactgt aaagttagca agaataatat ctaccttgtt
    12721 tgaaatcaag tattccgcac ggttggcagc atcgactgaa atgtatttaa ccttgacacc
    12781 aaggttttga gctagttggt tccctagttc aatatcgtag ccttggtaag aaccatcatt
    12841 gtcaacgtag ccaaacagtt ttttatctcc aaacacggcg attcgcagtt caccgctttt
    12901 tttgatttca tcgatagtgc gagctttggc agttgttttt ccagaggatg aaccagcgtt
    12961 tccacctgag ctacaagcag tgataaagat aagggcaaag gcaagtacta aaacagttaa
    13021 gagtggtttg aatagtttca taagaatctc ctttatagat atgagccgaa ttggctaaag
    13081 tcaaagacgt ttaaaaattc ctgggctcgt ttggtttgcg gattggtaaa gaaggcttga
    13141 gctgttcctt cttcagcgat tttcccttgg tcgaggaaga taatccggtc agcaatggct
    13201 tgggcaaact gcatttcgtg ggttactaaa atcatggtac ggccttcttg ggccaaatca
    13261 ttgataagtt ccagcacctc acgcaccatt tctggatcca gcgaagcagt cacctcgtca
    13321 aaaaggatga tttctggatg cattaggagg gcacggacaa ttgcaacacg ttgcttctgt
    13381 ccaccagata attgacgggc aaagctatgt tgtttatcca gcaaaccgac acgatctagt
    13441 aattgcaaag cttcttccgt tacttctttc ttgtcccttc cttgagtttt gatagggcct
    13501 aggatgaggt tttgtaagac atccagatgg ggaaagagtt cataactttg aaagaccatg
    13561 ccaatctttt ggcgaactag gtgaaaatct tttttatttt caacgataga ctgaccatcc
    13621 agaaaaatat ctccaccttg aatactttct aagccgttga ggcaacgaag gagggtactt
    13681 ttcccacaac cagatggccc taggatgaca acaacttccc ttttttgatt tctagagaaa
    13741 gtcctttgag gatgggattg tatccgaagg atttttttag ttccttgatt tctaagatag
    13801 tttcagacat ttagtttctc caatgttttt ctaagtgagt ggatagtttg gaaatagggt
    13861 agcaaactgc gaaatataag actagaatgg ttccataaat ccaaaatgaa gcagttggga
    13921 tggtcaggcg attgctatcg atgatttgtt gtccaacttt ggtcacttcc acaaccccaa
    13981 tcaaaacaac taatgaagtg gttttaatca tccgagtgac aagattgata gcctgcggta
    14041 gcagtcttct taagacttgt gggatgatga tgtggtagta aagttgaaca ttagtcaagc
    14101 cgagtgcctg tccactttca aactgatgtt tagggagaga agtgatagct ccacgtacca
    14161 agtctcccat ttcagctgtt ccccagaggg taaaaacgat aatagctgaa gtctcacctg
    14221 agatattgat attaaagttt cgagccaagc caaagtaaac gatgaagagt agcaccagct
    14281 ggggcatgat acggataaat tccagataca atcgtgttaa aaatcgtatg attctagaat
    14341 gggaggtcat gatgattccc atgactgttc tgaacatcat ggataagagg acagacagga
    14401 tggatatctc aatcgtaacg cccaatccct gtaagattct caggagatta tttccctgaa
    14461 agagtacttg gattcccgaa tcctgcatgg cggagcctcc tttctatcca gctaaagacc
    14521 agtgagatgg gtagcagcat gatcagataa gcaactacca acatagctag cgcaatgtct
    14581 gtctcatagt agagaccaat caaatccttg gcgacataca tgaggtcggc caaagccact
    14641 gctgagaaaa cagaggtttc cttgataagg aaaatgacat tggcactaaa ggaggggagt
    14701 gccaccgctg ttgcttgcgg aagaaccaca tagcgaaaga cctgtagagg tgtcagacca
    14761 atagcgaggc caatctcctg ctgggtttga ctgatggctt ccagcccact tcggaaagat
    14821 tctgccatat aggatcctcc taaaaagaca agcccaagcg ttgcacagac ttctgaagat
    14881 aggacaatcc cgattcgggg aagaccgaag tagagaaaga agagttgaat caaaaggggc
    14941 gtattacgtg acaattcaat gtaggctgtc gctacttgcg ccaaaacagg gattcgataa
    15001 tgtcggatga tactaacgat taaaccgagc agaaaggatc ccaaaattcc ccaaactgca
    15061 atatgcaagg tcagaaagaa tgccttttga tatagtggta gatattgttc aacaatggac
    15121 caatccaaaa atagaacctc ccatctagaa ataatacagt tattgtagca cttaaaatct
    15181 tctttggata atatctattt tttattgccg ttataaggat tttttaccat agacataaaa
    15241 tttctgaaat ttccaaacaa aatatttgaa aagttttgaa aaagagttaa gatatttttg
    15301 taatatacaa agtgaacgct tacttattaa ggagggcatt ttatgtcata caaaacaagc
    15361 aatgcagaag gtcatgtaga tttcatcaat acctatgatt tggagccaat ggcgcaacaa
    15421 gttattccta aagcagcatt tggctatatc gctagtgggg cggaagatac tttcacttct
    15481 ttccagtgat tttagcgtca ggttcttttt agtttttaaa gattatccgt gaatttcttg
    15541 cttatttatg ataaaatggg ggtatcgcaa aaaatgactc atcgtattca attttgagta
    15601 aaactaggag gatcccatgt ctacagaaca tatggaagaa ctaaatgacc agcagatcgt
    15661 tcgccgtgaa aaaatggctg cgctctgcga acaaggaatc gatcctttcg gaaaacgttt
    15721 tgaacgtact gcaaattcac aagaattaaa agataaatat gccaacctcg ataaagaaca
    15781 attacacgat aaaaacgaaa cagctactat cgcaggacgc ttggtaacca aacgtggtaa
    15841 aggaaaagtt ggttttgccc accttcaaga ccgcgaaggc cagattcaga tctacgttcg
    15901 taaggatgct gtcggtgaag aaaactacga aatcttcaaa aaagcagacc ttggtgactt
    15961 ccttggtgtc gaaggtgaag tgatgcgtac ggatatggga gaactctcta tcaaggcaac
    16021 ccacatcaca cacttgtcta aggctcttcg tcctcttcct gagaaattcc atggtttgac
    16081 agacgttgaa acaatttacc gtaaacgtta ccttgacttg atttctaacc gtgaaagctt
    16141 tgaacgcttt gtcactcgtt caaaaatcat ctctgaaatc cgtcgttacc ttgaccaaaa
    16201 aggattcctt gaagtggaaa cacctgttct tcataatgaa gccggtggtg ctgctgcccg
    16261 tccatttatc acccaccaca atgcccaaaa cattgacatg gtgcttcgta tcgcgactga
    16321 gcttcactta aaacgcctta tcgtgggtgg tatggaacgt gtctatgaaa ttggccgtat
    16381 cttccgtaac gaaggaatgg acgctactca taaccctgag tttacttcta tcgaagttta
    16441 ccaagcttat gcagacttcc aagacatcat ggacttgacg gaaggcatta tccaacacgc
    16501 tgctaaatca gttaagggcg atggcccagt caactaccaa ggtactgaaa tcaagattaa
    16561 cgaaccattt aagcgtgttc atatggtgga tgctatcaga gaaattactg gtgtcgattt
    16621 ctggcaagac atgactttag aagaagctaa agttatcgct gctgagaaga aagttccagt
    16681 tgagaaacac tacactgagg ttggtcacat catcaatgcc ttctttgaag agtttgttga
    16741 agaaacttta atccaaccaa cctttgtcta tggacatcca gtagctgtat ctccactcgc
    16801 taagaaaaat cctgaagacc aacgctttac tgaccgtttc gagctcttta tcatgactaa
    16861 ggagtacggt aatgccttta ctgaactcaa cgacccaatc gaccaactta gccgttttga
    16921 agcccaagct aaagccaaag aacttggtga tgatgaagcg acaggaatcg actatgacta
    16981 cattgaagct cttgaatacg gtatgccacc aacaggtggt ttgggaatcg gtatcgaccg
    17041 tctctgcatg ctcctcactg atacaacaac tatccgtgat gtattgctct tcccaacaat
    17101 gaaataaatt cttatcctct ggctcttacc agaggatttt ttgattcaaa aagagactga
    17161 atttaaggag aaaatgaagt gtagtatatt gaagttgaaa tagtacactt tgatttctaa
    17221 gacattgtta gaaattggtt taaattccct aagcaatttg tgcatgtttt atttcatttt
    17281 acgatagtac gctgaaactg ttcaaaaagt actagaaatt gacttggatt ccccaattga
    17341 tttgttcaga ttcactataa ataaaaaatt aataagtggg ataggaagtt agcgtcaact
    17401 aggatagtat cttgcttaaa cagtatatat gggactgata taagtccata ggtcctatta
    17461 gaggatgttc tggtgtctta ttcacttgtt ttttatagta ttagtagata gaatcagcaa
    17521 ataaaaaagt agttcaaatg cctggcagca aaaaatctca acgattcact taatatagac
    17581 taaggtttag agtttaagga aagtagggct agtatattgt atgaaaaaat aagatggttt
    17641 ttaagcaaaa ctcttgaaaa tgattgaaaa aagagttatt atagttgtat agtaaaaagc
    17701 aaacgcttac ttaatcgagg aggacagttt atgtcataca aaacaagcaa tgcagaaggt
    17761 catgtagact tcatcaatac ctatgatttg gagccaatgg cgcaacaagt tattcctaaa
    17821 gcagcatttg gctatatcgc tagtggggcg gaagatactt tcactttaag agagaatatc
    17881 cgtgccttta accacaagct catcgttcct catacacttt gcaatgtaga aaatccaagt
    17941 acagagattg aatttgcagg tgaaaaacta tcttcaccaa tcattatggc gcctgttgcg
    18001 gcccataaat tagcgaatga acagggggaa gtggcgactg cgcgtggtgt gcatgagttt
    18061 ggttctcttt atacaaccag ttcttactct actgttgacc ttccagagat ttctgaagcc
    18121 cttcaaggga cacctcattg gtttcaattt tactttagta aggatgacgg tatcaaccgc
    18181 cacatcatgg accgtgtgaa ggctgaaggt tataaagcga ttgtcttgac ggcagatgct
    18241 actgtagggg ggaatcgtga agtggataag cgtaatggtt ttgtcttccc agttggcatg
    18301 ccgattgttg aagaatacct gccagaaggt gctggtaaat caatggactt tgtttacaaa
    18361 tcagctaaac aacgcttgtc tccacgcgat gtagaattta tcgctgaata ctctggtctt
    18421 cctgtgtatg tcaagggacc acaatgccgt gaggacgttg aacgttcgct tgctgcagga
    18481 gcttctggta tctgggtaac caaccacggt ggtcgtcaaa tcgacggtgg accagctgcc
    18541 tttgactcgc ttcaagaagt ggcagaagca gttgatagac gtgtgccgat tgtctttgac
    18601 tctggtgttc gtcgtggtca acacgtcttt aaagccttgg cttcaggagc agacttggta
    18661 gctattggtc gccctgttat ttatggcttg gctctcggtg gtagtgtcgg tgtgcgtcaa
    18721 gtctttgaac acttgaatgc ggaattgaag acagttatgc aattgtctgg agctcagacc
    18781 attgaagatg tcaaacactt taagctccgt cacaatccat acaacccaac cttcccagtt
    18841 gaccctcgtg acttaaaatt gtattgataa aacagattgc ctccactgaa tgtggaggtt
    18901 tttcttcgtg tattggaaga ataaattgct atcgaaaact atagtaaaat gaaataagaa
    18961 taggacaaat caa
//
LOCUS       DBERDS010000040        18437 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.040, whole genome shotgun sequence.
ACCESSION   DBERDS010000040 DBERDS010000000
VERSION     DBERDS010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.040"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..800)
                     /gene="lytB"
                     /locus_tag="ACL73E_001548"
     CDS             complement(<1..800)
                     /gene="lytB"
                     /locus_tag="ACL73E_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGS0801496.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGK"
     gene            complement(842..1780)
                     /locus_tag="ACL73E_001549"
     CDS             complement(842..1780)
                     /locus_tag="ACL73E_001549"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGS0801497.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEYAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1791..2591)
                     /locus_tag="ACL73E_001550"
     CDS             complement(1791..2591)
                     /locus_tag="ACL73E_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGS0801498.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2841..3221)
                     /locus_tag="ACL73E_001551"
     CDS             complement(2841..3221)
                     /locus_tag="ACL73E_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0801499.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3279..3638)
                     /gene="rplT"
                     /locus_tag="ACL73E_001552"
     CDS             complement(3279..3638)
                     /gene="rplT"
                     /locus_tag="ACL73E_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGS0801500.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3690..3890)
                     /gene="rpmI"
                     /locus_tag="ACL73E_001553"
     CDS             complement(3690..3890)
                     /gene="rpmI"
                     /locus_tag="ACL73E_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGS0801501.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3923..4453)
                     /gene="infC"
                     /locus_tag="ACL73E_001554"
     CDS             complement(3923..4453)
                     /gene="infC"
                     /locus_tag="ACL73E_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGS0801502.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4469..4600)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4760..5941)
                     /locus_tag="ACL73E_001555"
     CDS             complement(4760..5941)
                     /locus_tag="ACL73E_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801503.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYFNSQTANSVS
                     LERELETRLVDRERVINEYEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKDYEFVSNDPTASSELKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEAIIPTLFVIGIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYSIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     gene            complement(5945..6532)
                     /locus_tag="ACL73E_001556"
     CDS             complement(5945..6532)
                     /locus_tag="ACL73E_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0801504.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6565..6782)
                     /locus_tag="ACL73E_001557"
                     /pseudo
     CDS             complement(6565..6782)
                     /locus_tag="ACL73E_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6931..9171)
                     /locus_tag="ACL73E_001558"
     CDS             complement(6931..9171)
                     /locus_tag="ACL73E_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGS0801505.1"
                     /translation="MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCL
                     FFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQNLADSVEGVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLIKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSLRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPTFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9155..9805)
                     /locus_tag="ACL73E_001559"
     CDS             complement(9155..9805)
                     /locus_tag="ACL73E_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS0801506.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9873..10442)
                     /locus_tag="ACL73E_001560"
     CDS             complement(9873..10442)
                     /locus_tag="ACL73E_001560"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801507.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10619..11730
                     /gene="ald"
                     /locus_tag="ACL73E_001561"
                     /pseudo
     CDS             10619..11730
                     /gene="ald"
                     /locus_tag="ACL73E_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12031..12357)
                     /locus_tag="ACL73E_001562"
                     /pseudo
     CDS             complement(12031..12357)
                     /locus_tag="ACL73E_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12360..12860)
                     /locus_tag="ACL73E_001563"
     CDS             complement(12360..12860)
                     /locus_tag="ACL73E_001563"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801508.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13053..14021)
                     /locus_tag="ACL73E_001564"
     CDS             complement(13053..14021)
                     /locus_tag="ACL73E_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGS0801509.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14107..14322)
                     /locus_tag="ACL73E_001565"
     CDS             complement(14107..14322)
                     /locus_tag="ACL73E_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGS0801510.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14331..15185)
                     /gene="cvfB"
                     /locus_tag="ACL73E_001566"
     CDS             complement(14331..15185)
                     /gene="cvfB"
                     /locus_tag="ACL73E_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGS0801511.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15245..15802)
                     /gene="frr"
                     /locus_tag="ACL73E_001567"
     CDS             complement(15245..15802)
                     /gene="frr"
                     /locus_tag="ACL73E_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGS0801512.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15811..16548)
                     /gene="pyrH"
                     /locus_tag="ACL73E_001568"
     CDS             complement(15811..16548)
                     /gene="pyrH"
                     /locus_tag="ACL73E_001568"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGS0801513.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16632..17966)
                     /gene="trmFO"
                     /locus_tag="ACL73E_001569"
     CDS             complement(16632..17966)
                     /gene="trmFO"
                     /locus_tag="ACL73E_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGS0801514.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18211..>18437)
                     /locus_tag="ACL73E_001570"
     CDS             complement(18211..>18437)
                     /locus_tag="ACL73E_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS0801515.1"
                     /translation="SQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYV
                     ECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT         5325 a         4174 c         3394 g         5544 t
ORIGIN      
        1 attttcccat caaatttgag ataaaaccaa gattccttat cccaaatcca ttcattggct
       61 gccatgtagc caccggattt tagataataa tagtgaccat tctcgaaaat ccattcttta
      121 tcagcatagt ttccattttc tttgatgtaa aaccaagatt ggtattgttt gtcaaaaagc
      181 caaccttgct gtactttggc accactagca ttcacataag cttgattaat ccactgactt
      241 gtcagtagat aaccaccgga tttgaaataa tagtccttcc ctttaatttg gagccattct
      301 ttctctgcgt gctgtccatc tgctttgata taaaaccaag catcgtattg agaatcatag
      361 acccagtctt ctattacttt ggcacctgtt gcaccaacat aggaagttcc tacccaagca
      421 tttcttttca tctttccatc ttggtcaaga taataaaagg ctcccttgtc ttctacccat
      481 tctgatttgg ccatatagcc accagatttg aggtaaaaat agtcgtcacc ttgctttagc
      541 cattcatttt cagcatagtt agcatctgct tttatataga accaagattg ataatgagta
      601 tcaaaaaccc actcatttgc tgcttgactg ccatcttctt tcagatactg ttttccttgc
      661 caagtaccat cactagccat tgcaccctct ggactagcta agaaaaatag cagagctaaa
      721 aaaataaatc ttactttctt cattaacctt cttcctctgt tcttatttat tttattgtac
      781 caaaattctc ctaaattcat attacaaact aataaaaaat caagaacaga ttgattgcag
      841 tttacctcag agactctttt acttcctgac ggagttcttc cagactgcta ataccgtatt
      901 tatccatgac ttttggtaaa ttttcgatga tgtcagggca ggcataagga ttggtaaagt
      961 tagctgttcc aactccgata gcagatgccc cagccagata catttctagg gcagcttcag
     1021 ccgaatccac tccccccatt ccaatgatag gcaggtctgt tgtttgggct acttggcgga
     1081 tgagtttgag ggctactgga aagactgctg gacctgacat tccacctgtt ccattggcca
     1141 agattggttt tctggttttg aggtcaaagc gcattccaac cagagtattg atcatggtca
     1201 agccacttgc tcccgcatat tctgcagctt ttgcgacagt aacgatatcg gtcacactcg
     1261 gggttaattt gacataaact ggcacttctg aggcttccac agctgctttc accacatcat
     1321 aagccaaatc tggatcttga ccaatcaaaa gtccatgatt acagtggtca acattgggac
     1381 aagaaatatt gagctcgata gcttttacat tagttgcctt ggaaatccca tgagaaacag
     1441 ctgcatactc ttgttttgaa aaaccagcta cattggcaat aataggaaga tttggatatt
     1501 ctctttccag ccaaggtagc ttttcagcca aaacaacctc taaaccagga ttttgcaagc
     1561 caattgcatt gagcatacca gcaggcgtct ctgccactct tggagttgga ttcccaaaac
     1621 gtggttcaag ggttgtcgcc ttgatcataa tagaacctaa aaggtctaaa tcatagtact
     1681 tggcatactc ttgtccaaag ccaaaacagc ctgatgctgg aataatcgga tttttcaaat
     1741 ccaaaccagg tagagacact tgtaatcgat ttgtagtcat aattttctcc ttataataca
     1801 actgttcctg tgcggaaaac aggaccatct tcacagacgc gttggctgac cgtctcgctt
     1861 tctggtactt ttagaacaca ggcatagcaa gctcccatcc cacaagccat acgagattcc
     1921 agagataaat aggctcttgg gtgatcatca aaggtttgat tgatatactt catcattcct
     1981 ggagccccac acgagtaaac agcatcaaac tgactatcta aatcattgat aacaacggaa
     2041 acatttccct tgatgccata agaaccatca tctgtcgtta caaagacctg accatactga
     2101 gccaattccg ttttcaaaat aacagcatcc ttattagcaa aaccgaggac tgtcactact
     2161 ttcactccac gttcatgcaa ttccttggcc acctcaagca agggtggaac accaatccca
     2221 ccaccaacaa ggagaacctg attctgctca tcaaggtcag acaagtcaaa accatttccc
     2281 tgaggcccca tcacatcaag agtgtctccc tgacttaagg ttgaaaaaat tgcagtccca
     2341 gctccctcaa tccgataaat gaggtgacac tgcttgtttg ccttgtcaat agacgaaatt
     2401 gaaataggac gacgtaagag atgggcatcg tctggtacac gcagatgaag aaattggcct
     2461 gctcgcatgg cttcaaccat ttctccttct aggactaatt caaagattgc tggcgcgatt
     2521 tcctcttgtg caaccacctt catggtttcc aaccgaatga cacccaaacg cttcttacat
     2581 gtgagattca taacttttcc tccttaaatt ttaaggggac cagataaaga aaagaccttg
     2641 ctagtgcaag gcctcagtta aaatcgtaca acacaagaga gcacactcaa aaggtctcct
     2701 ctagaaaatt gcactattct tttatctgac accttgtgag tctctctgga ctccccttaa
     2761 aggttgaatt tttattagta tactctttca gctaaaaaaa gtcaagtaga aaacgaatat
     2821 tctacttaac ttgcacgaaa ttatttttca cgaatgactt cgaccttata tccatcaggg
     2881 tctttaacaa agtaatagtt tggtgtagtt cctggtagac catttggctc agtcacttca
     2941 tagccttttg cactgtgttc ttgatgaagt gcctcaagat caggtgtact gagggcgata
     3001 tgggcaaacc catcaccaac cacatacgga ccgtgatcgt agttataagt caactccaac
     3061 tcataatcat caccctcaag acctagatag acaatcgtga aggcatggtc tggaaaatct
     3121 ctgcgacgca attctttaaa accaaaagca tcttgataaa atgcgattga tttttcaaga
     3181 ttttctactc gtaagcaagt gtgtagcatt tttgaagcca tatctttctc ctttattttt
     3241 aaaaagactg gacaatcctg ttccagtctc atcagttgtt atttaccaag ttttgcttta
     3301 gctgcatctg caagagctgt gaaagctact gcatcgttaa cagccaagtc agcaagcatt
     3361 ttacggttaa cttcgatctc agccaatttc aaaccatgca tcaattgtga gtatgaaagt
     3421 ccgttcatac gagctgccgc attgatacga gtgatccaca atttgcggaa gtcacgtttt
     3481 ttctgacgac ggtcacggta tgcatagtag taagagttca ttacttgttc ttttgcagta
     3541 cggaacaaga tgtgtttagc tccatagtaa ccttttgcta atttaagaat acgtttacga
     3601 cgtttgcgtg atacaacgcc acctttaaca cgtgccatgt tttatttcct ccaaatattt
     3661 cctagaattg tttacttaca gtcaagctat tatttcaagc gagtaagcat tgctttgata
     3721 cgtttgtaat ctcctgaatg caccatagat gctttacgaa gatgacgacg ttgtttctta
     3781 gtttttccgt ggaaacggtg agaagtgtaa gcacggaaac gtttaagtcc accagaacct
     3841 gtacgtttga aacgtttagc tgatgcgcgg tgtgtttttt gttttggcat gattttttct
     3901 cctttattta actttctgac aattattttt tgtcagtcgc tggcgccaat tgcatgaaca
     3961 tttgacgtcc atccatttta gcacgttgtt cgatgatggc aatatcttga gttgcttcag
     4021 caaactcggc taaaactttt gcaccaatct ctttatgggt aatcatacga cccttaaagc
     4081 gaatagatac cttaacttta tttccttttt caaggaactt acgtgcatta cgaagttttg
     4141 tatcaaagtc acccttgtca attgttggac ttagacgaac ttctttcaca gtaacaacgc
     4201 tttgtttttt acgttgttct ttttgcttct tctggtactc aaatttgaac ttaccgtagt
     4261 ccataatttt tgcaacaggc ggtttggctt ggggttgaat caatactagg tcaacattag
     4321 cgttatcagc caaagcttgc gcttcactga gtggcttgat gcctagctgt tctccctcaa
     4381 gaccaatcaa gcgaacttca cgtacacgaa tctcatcatt gatgaataag tcttgctttg
     4441 ctatggtttt cacctctttt gttttattag agaaaaacaa tagcggactc gtaaatatac
     4501 aagcccgcac gttatgatag cgtttcttcg aaacttttca tccgtagggc caggcaactt
     4561 aatgtcacaa ggcgagaagc tctcacttct gcttttctca acttttatat gataccaagt
     4621 tttctagctc ttgtcaagat aaaaagttat tttttgaaaa gtttgtgttt gtattttggt
     4681 ttggttttcg aatcaaaaag agagaaccaa gttgattctc tccctatgtt agtttttctt
     4741 tagcttccct ataggaaaac taaactttaa aaacttcctt tttacgtgaa cttccccagc
     4801 tttcgataaa tagaatcccc actaacaaaa ggataatcag gcaaggaagt aagaccatcc
     4861 ccatgctcca atttagatcg acattatcaa tctgcttaga taatcttcca gataaaatct
     4921 ccactgaacg caagtaagta aagggaatca gatgtgcaat cctttgaaga ggctgaattg
     4981 tttggatgcc aaacaataag ccaacaatcc caatgagtga aagaaagagg acaggcattt
     5041 tttgcttgaa aaaataagca atcaagtaca caacttccac aatgacgata aaggctaaga
     5101 aagctaagag taagccagga aataatacat cttgtatttt cccaatagtt acttcttgat
     5161 tcactaagct ataaattgag tagggataat ctaactgtcc aaaaccactt atcagacttc
     5221 ccactagaaa agaaaagcca cagattccga taaacagcac agttacatat cccactccaa
     5281 ctccaagaga ggatattgca aatgtcactt ttgaaacagg atataagtga gctgtgtcca
     5341 gatgattttg atatctttct gcaaatagtt gtgttagcat aaaaataata ccaatcacaa
     5401 ataaggttgg gatgatagcc tctaaaatcc agacaatctg atcaatcccg tgggtcggaa
     5461 actccaaagt atgtgctttt atgttcaagg gatacagggc ttgataaatc ttccgttcgc
     5521 ggtcaacccc catttttaat tcagagctag cagtcgggtc atttgataca aattcataat
     5581 ctttctcttc atcttgccac tgcagatagt aggcctcttt ccagcgccct tcttttagta
     5641 aagttagaat ttctgtcttt cgcgtcaaaa gatttttttg cacgtctaaa ttatttttag
     5701 caaactggta ttcctccgag ctggtatcag acatttggga gagtttctct tcatattcat
     5761 tgatgactct ctcacggtct acaagacgag tttccaactc tctctccaag ctgactgagt
     5821 ttgcagtctg actattaaaa taaaaagtaa caccgagtac agatacaaat aaagctaaga
     5881 taatccagtt taagcggctt ttgaaaactt ttttcaataa aaatagacta acatctttca
     5941 taaactaaac ctcttctatc tgcccctgat gaatggttac tactctatcg cagatatcaa
     6001 ccaactcttc cttatagtgg gaacttaaaa gaaccagctg ttcttgtcta tcgatttgtg
     6061 ctaacctatc aaaaaacttc tgtcgataat actcatctaa gccatttgta atctcatcca
     6121 tgagccagca tttggcctga ctgagaaaat acatagcaat caccaagcgt tgcttcatgc
     6181 ctaaggaata cttgcggatg ggaagactga tatagtcagc catttcccag taggcgattt
     6241 catctctcaa gtttaggtct gacttccaga tgtttttgat aagacgaagg tagtccatcc
     6301 cacttaagtt tccatccagc cattcaatac tctcataata aaataaagaa ggaggagctg
     6361 cgatatttcc actacttatg ggaattaaat tgctaatggc acggaacagg gtcgtctttc
     6421 cagagccatt gatagcaaga agaccataaa acctaccctt tttaaaggtg aaatccgcat
     6481 cttgcaagat gacttgtcgc gtttttaagg tcacatgagt aagctgcaac atatctagcc
     6541 ctcctttttc tcactcttta agaattaata gcctccgctg taatagttta tgatctcata
     6601 acgaccgtag ttccagccag aaccaactgg atactcagaa tagctgtaat aacgagacca
     6661 tgacggaacg ttagtatgtc tatatccatg gaaattcata ctagacttat agaagatatt
     6721 ccaatcatac cgatactttt aagaacactc ttagcagata cactggactg aagaagacca
     6781 atagattata aactaactaa taaaataact tttgctgatt tttaatgatt ttatatcctc
     6841 aatattgaat acgttttcat tataccattt ttatcattat tatgcaacaa atttttagtt
     6901 tatttcacta atctacaaca tttatctttc ctatcgaaca ctttcgattt tccaactatc
     6961 caacccctta aaacgtatag ctccttgctg gtcagttcga taaactttgc tattgatacc
     7021 ttccagtcgt gtcaatgttt cctgatgggg gagtttcatt cgattgctct ttccaactga
     7081 gataagagta agctctggtt tgagtttttc tagaaaggtt ggacttgatg attttttatt
     7141 gccatgttgg ctagctttca aaacatttac tttcaagtct ggatagtgct tcagcaagtc
     7201 cttctctcct ttctcctcca aatttcccgt gaagagaaat tgcttatcca agaatttccc
     7261 atacagaact agggtatcat cgtgtcctcc atctcccatt ttccttagag atagaacttc
     7321 taactgactt ccaaaaatgg gcaagttctc ccctactgtc atactacgca cctttgtttg
     7381 agtcgcctgt agttctacca caaattgctt ctgcttcaaa ctgccttttg atactaaaat
     7441 ctcccctaca tggaaagcct tggtcacctc taacaaatct ccgacatgtt ccttgtccgt
     7501 atttgtcaaa atcagctggt caatcttagc tactcctcga cttttaagat agggtatcaa
     7561 gcttctctgt gcattgctgg tcgtcatctt ttcttgccat ttttcgattt tcttataaga
     7621 ttctgcctta ccacctacat ctatgagaat ggttttccca gttacatccc gtaggaaaat
     7681 actttctcct tgccccacat ccagcatggt gatttcattt tccagtggat acttgataag
     7741 gaaaaagaga cctgtaatca ataaactcaa tactgttaat cctttaatgt ttttcctcaa
     7801 atcatagacc aaagccaagg aaattaacaa taagattaaa agccatgcgt tgggttgacc
     7861 aaagacaagc ggtctccttg ccacctgcga gaccaagcga ataatgccct ctaaccattc
     7921 aaagataaag ttcagctgaa tgactggata gagaaaggaa aggacaaata aaatagacaa
     7981 gagcggtaag aaggtcaagt caaatagaaa ggaaaagaca aaggtcaaaa ggatagacca
     8041 aggttgaaat tccgcaaaat agaaggatag aatgggcaat atgcccaagg agatgactag
     8101 actttcacta gtaacagcct tgagcccctc cccttctttg ctggtcatgg tcaggataaa
     8161 agcataagcg caggacaaga ctcctcctgc tgtcaagaaa aagtttggca tgacaataaa
     8221 gaggacaagc accgtcaagg caaaattatc caagccctta accccatgtt gagccagtag
     8281 cttttgcaag agactgcgaa taaccgatgc tgaaaatcca gttagtcccg catagataag
     8341 ggaaaaggga taagtcagcc atttcaactt ttcttgggtc aagcccaatc gcaagagaag
     8401 tttcttaaat ccattcatga aaaaacctac ctgcatgcca gatagggcaa agaggtggat
     8461 aattcctaga ctggaataaa gctcattcat ctcctcaaag tcggtgtcca gatgtcccag
     8521 caagagtcct gtcatgtaat tgcgcatagg gtctggaaag tgcgtcttaa tccaaaccac
     8581 agcctttcga cgtaaactgg acaagttttc tcctatatcc caactgccaa tcttttgaag
     8641 tgactggatt gttttgatat tgagagtctg gtaaattccc tgagtcttca gataggcttg
     8701 gtaattaaag ccaccaaaat ttctctgccc ttctggctcc gaaagcttcc cttctagtcc
     8761 tatctcatgc aggtcggtta aagcttgaaa ggcttctttc tcctcctcgg actggagttt
     8821 ataatagact tggaaagcac gaccgttaga cttgccacga aaggatagac tatcaccatt
     8881 aaccttaata gtatcaggca aaatccgtac cccttcaaca gaatccgcca gattttgact
     8941 cgcttgactc tgttgccaat tttgaaaaac aaaccaaaat ccaaagattc cacaaatcac
     9001 tagaactttg ctagcagatt tccaaggaaa ttggaaaaag agacagacta gcagaaaaac
     9061 aaagcccaac aaagcaagat aggatgctga gaaaatagcg taataaaacc aaagtaacaa
     9121 aaaactcagg taaattaggg gaatggggat gttcttaatc cactgtaaca tagtctttta
     9181 gcttttctat ggtcttagca ccaatgccag agaccttctt gagttcatca atcgacttga
     9241 atttcccatt tgcctcacga tggtctataa tgtcctgagc tcgttttcct cccagtccct
     9301 taacctgttt aagctcttcc agactggcct tgttgagatt gaccttcttt tccttgcttg
     9361 ttgaagaagc tgtccccgaa ccagtctgtt gactaactgc ttcttctccc ttagtaggaa
     9421 cgtaaaccag agcctcatca ctaactttct gagctagatt gagcgacttg ctgtctgctt
     9481 gctctgtcaa gccaccagcc ttctgaacag catcattgac tcgactacct acaggcaagt
     9541 cataaatccc tggcgatttg acagcacctt tgacatctac tgtgattaga tcttgttcaa
     9601 ggggttcttc cttctcttcc ttgttcactt ccttttcgga taccaaatcc ttggaaacag
     9661 ctgcaacttc agcctgcaaa ttcgtttcct ttacaggtgt ttgtggagct ggctttagca
     9721 ggaaaaatcc gcctacaagc aagcccagac cagtacagat gacgatgatt ttatactctt
     9781 tgattttctc gataattgct tccatatttt ctcctctctt agattattcg taagaggaag
     9841 aaaaaacagt cgaaaaattt cttttcaact gcttatttat ttgcaaaata gtcttccttg
     9901 gtcaagacat aatgaactct tgtcacgatt cggccttttt catgctggtc catacaagca
     9961 tatggttctg catgggaaaa acgcatgcct gatttctcca tgacctttcc tgacgcagga
    10021 ttgtccttat cgtgaagggc agtcaactta ttcatcccta tcttctcaaa agctagctca
    10081 atcacagcac gattggcttc tgtcgttaat ccttgattcc aatacttttt attgataatg
    10141 tagccaatag ctgccttctt aagaacagaa tcaatcttgt gcaagtcaat ggttccaata
    10201 aactgaccat tgctttttag ttctattccc caacgtccca agggattagc caaatagaac
    10261 tgagcaatgt tattcttggt ttcttccaag ctttgattgg ttggaaaagt gtaacgtgta
    10321 ttacccttgt ccgaggcata gtcaaacatt gcttccgcat catccaaagt tacaggtcta
    10381 agcaataaac gctccgtttc tatagacgga tactgggcaa gttttacaaa aattgattcc
    10441 atacttttcc aaccaatcaa agcttgattt tcactagtct agcataaaaa atttggatga
    10501 caagtttttc ttgatttttg aagcggtttc atatacaatg aaaccgtcac atttttgatt
    10561 tatgaactgg aatgtgacaa ccaaaacaag accgtcaatt gaaaggtagg ttatctcaat
    10621 gttaatcgga atcccaaaag aaattaaaaa taacgaaaac tgtgtcgccc tcacacctgc
    10681 aggtgttcat agcttagtta gtcgtggtca tcgtgtcctt atcgaaacaa atgctggtct
    10741 cggttctggc tttactgatg ctgactatca aaagcaagga gctgagattg tcgctactgc
    10801 tggtgaagct tgggcagcag agttggttgt gaaagtaaaa gaacctttaa gttctgaata
    10861 cggttacttg cgcgacgatc ttcttctctt cacctacttg cacatggccg ctgctccaga
    10921 attagcagat gctatgttag cagcaaaaac aacaggaatt gcctatgaaa ctgttcgtga
    10981 caatcaagga caactaccgc tcctcgttcc tatgagtgag gttgcaggtc gtatggctgt
    11041 ttaaatcgga gctcacttcc ttactaagca agctggtggc tctggtgttc tacttggtgg
    11101 tgtaccaggt gttccaaaag gaaaagtaac tatcatcggt ggtggtgtcg tcggtacaca
    11161 tgctgcccgc atcgcccttg gtcttggtgc tcaagtgact attttagata ttagtgccaa
    11221 gcgtctctca gttctagaag aagtctttgg aagtcaaatt caaactctta tgtctaattc
    11281 attcaacatt gaagcaagtg tgagagatgc tgatgtggtg attggagcca ttctcatccc
    11341 tggtgcaaaa gcaccggaat tggtgacaga tgagatggtc aaacaaatgc gtccaggctc
    11401 tgtatcgttg acgttgctgt tgaccaaggt ggcgttatcg aaacagctga ccgtgtgaca
    11461 acgcacgatg aacccgtcta tgaaaaacac ggtgttctcc actatgccgt tgccaatatc
    11521 cctggtgcgg ttgcccgcac ttcaaccatc gccctaacca atgtcactct tccttatatc
    11581 gaagctttgg ctggcaaagg attcgcacaa gcaatctctg aagatgaagg cttgcgtcaa
    11641 ggtgtgacca cttatcaagg ttacttgact agcctaccag ttgctcaagg acttaatcgt
    11701 gactacactg atatcaatga tttagtataa attttgaaaa gaaaagggtg acttcgcaag
    11761 tcctacccac tgtgctttgt gtcatcagct attacatcgt tggtttattg tactgtatac
    11821 tttgcaactg gagactttcg ttccagactc aattgtgcat aagaaactct aaattgaata
    11881 aagtcaacag agtttcgccc aaccacttcg tcttgtaatg acaattatat aaaccaaagg
    11941 aagctgagct ctttagtccc agcttctttt tatatataaa attttacccg tgcaaagaca
    12001 gggccttagc agacttcttt tttacttcgt tcacccttgc tttttctttt taggtttggg
    12061 cgttggcagt tggttataca tagctaaaat caggtcttat agaaacatct tattatcaag
    12121 ttcttccact caaatcattt ctttggcacc tttgtatgga aactcaaaag aagattggtc
    12181 aatcttatct aagactgctt gcacgggttt aactaaaaag cgatcatcat aaatgccgcc
    12241 aataatcttg ccgcggaagt aaagaatata ctcccccatc atggaacggt aagtcacatc
    12301 atctaatcct gataattgtt ccaaaacaaa ttccaaatag ttcttacttg atgccatttc
    12361 taatcttcta ggctctgttc agcgataaca accgtataga gttcttgctt aacctcgcat
    12421 ccaattgatt taaaaccctg cttttcccaa aaatgctgag attgcggatt tcccttaaca
    12481 taagccaaac gtgcctttcg aaagttctta gcaaaataag ctagtgcttc tgtcacaata
    12541 tgactaccaa tccctttcct ctgataggct tgatcaacca taaacaaacc aataaaaaca
    12601 gtctcctcat caggataggc atagacaaaa tccataacag ccacaaggtc agatccattc
    12661 caaaatccaa caaaaaactt atcagcctta gctttacctt caggtagaca aagcatgtcc
    12721 tcttttacag ttgcaaaatt tggctctggt ggacaatgct gaaaatacag aggattactt
    12781 tcatataaag ataaaatact tggaatatcc ttttcagtta gtatcctaca actgtaatac
    12841 ttagatagtt ggtcaatcat cttttcaaat tcctactttc ttgtgccctg tgattatgac
    12901 acaggaagat gcactgatcg tcatcagcca cataaaagtt ctttccatcg tgcctaatcg
    12961 ttgtctcaga cctttggata aaacctttag cctatacaac tggattttcc tctctcaaaa
    13021 gtatattctt ttgcaggcga acttcctcaa aatcagtcgt gtgcaacttc agtagaatat
    13081 tcataggctc ggataatctg agcgacaact ggatggcgaa ccacatcctt ggctgaaaaa
    13141 tgaacaaagt caatctgatg gatgttcttg agtttctctt gagcatcaat caaaccggac
    13201 ttgacattac gtggcaggtc aatctgactg atatctccat tgacaatcat cttagaatga
    13261 aagcctaaac gcgtcaagaa catcttcatc tgcatgatgg tcgtgttttg cgcctcatcg
    13321 agaatgacaa aggcatcatc caaggtccgg ccacgcatat aggcaagggg cgcaatttcg
    13381 ataatttcac gctccatgag acgagtcgtt tggtctttcc caagaatttg atacaaggca
    13441 tcgtaaacag gacgaaggta aggatccacc ttctccttaa gatcacccgg aagaaatcca
    13501 agactctctc ccgcttccac cgctggacga gttaggataa ttcgcttgac ttgcccacgt
    13561 ttaagggcag tcactgccaa ggtcactgca aggaaggtct tccctgtacc tgctggccca
    13621 attccaaagg tcacatcatg ctgtttgaca ctgtccacat aaagcttttg ccctagggtt
    13681 ttgacacgga taggtttccc agtattatct ttgataattt cttcttcgta aagggcgaca
    13741 aacttgtcaa tttcatcatt tttgaccatg ctaatcgcag tgactacatc tggcgtacca
    13801 acggtcatcc cacgatttac caagaccatc aaagcctgaa taacttgacg ggcttcctca
    13861 caggcagact cttctcccaa aacctggaca atctccgtac gagcatgaat cacaacatca
    13921 agctcttctt ccatcaaacg aagatggcgt tcattggaac caaaaagatg aaacaggtca
    13981 tctggatgac tcagttgaat gtctattgaa tgttccttca aataaagaac ctctctaatc
    14041 cttttatttc tttttattat agcagaggga tggagaaatt actagcccaa acccaatgaa
    14101 taaatgctag tgttctagat attcctgcca aatgctgtca aaatctccta ggttaaaaga
    14161 gaaactggca tgctcctcca aaaagcgact gacctcatca aaatcatctg tatgttttgg
    14221 aaaagctgcc tcttcaaaag cgaggtctgc caaaattgct ttgggactgt tacttttagg
    14281 attgcgctcg gtcatgagcc aagtgtaaaa tgattttctc ataagcctcc ctaaatcaac
    14341 tctgtcccaa actggtcctg cttgatttta ccagccttca taagaccacc taaagctttc
    14401 ttgaactgac ctttagaaat gccaaaggtt gccttgatgt cgtctggaga tgacttatca
    14461 tttaaggtca tgaaaccgcc attactttcc aaataagtca aaatcatctg agcatcgttt
    14521 tccaacattt caaaggagcg tggtttgagg gagaggttca gagtgcggtc cacttcacgg
    14581 aaaccaataa cgcgcgcatc taatacttgc cccaaacgtg gctctgcgta acgctcgcta
    14641 ggatgaataa aaccaagcat attattttct ggtaggtaaa caaaagttcc tgacagcttg
    14701 agacggtaaa caatggctgg ccagttttgg ttctgcatgt tgttgtaggc aggacgagca
    14761 agacgttgga agtcttcttg ataagccaag aggccccaga tacggtcttt cttatccact
    14821 tcaagacgga tgtagagttg gtcgcccttc ttaggccaga gttccttgag ctcagggaga
    14881 atatcgagtg acacaacgat ttccttgtca ggaaggcctg tatccacaaa gacacccaaa
    14941 tccttacgaa cctctgtgac acgtccccaa ccaaattggt cctgagtggc agtcacttct
    15001 aaggttgtca ggcggagttt ttgcttcata tccgtgtatg caaaaccttt gaccgtatcc
    15061 cctactgtat gttgaccttc ttccttagca agagcatagg tttgaccatc cttttgcaca
    15121 aagtaaaaac ggtcattttc atcgatgatc agtccaacga taaaacttgc aagatttgta
    15181 ttcatatttc cttctttcga ataaaactca gccagcaatg ccaactgagt ttttctgttt
    15241 atttttagac ttccaaaagt tctttctctt tgttagcagt catgtcgtcg atgtgtttaa
    15301 cagcatcgtc tgttactttt tgaatatctt tttcaagagt cttcaattcg tcttcagtga
    15361 tttcttttgc tttttcttgt ttcttagctt cgtccatagc atcgcgacgg atattgcgga
    15421 cagccacttt agcattttcg ccgaccttct tcacttcttt agcaaggtca cgacgagttt
    15481 cttctgtaag agctgggata accaagcgaa tcacagaacc gtcattagcc ggtgtgatac
    15541 caagatcaga agcgttcaag gcacgttcga tgtctttcaa tgaagacttg tcaaatggtg
    15601 ttaccaacaa aacacgcgct tctggaatcg taattgaagc gatttggtta agaggagttt
    15661 cgactccata gtattctaca tgtacacggt caagcaagct tgcattggca cgaccagcac
    15721 ggataccacc aaattcacga gcaagtgatt ggtgagattg ggtcattctc tctttagctt
    15781 tttcaataat tacgttagcc atattctttc ttattccttt tcttcgatat tatttgaaac
    15841 tgttgttccg atattttcac caaatacgac acgtttgatg ttgcctgatt ggttcatgtt
    15901 gaagacaacc aagtcaatgt cgttgtccat tgagagggtt gaggctgttg agtccatgat
    15961 acgaagacct ttgttgataa catcacggtg ggtcaattct tcaaacttaa cggctgtctt
    16021 gtccttctta ggatcggcat tgtacacacc atcgacgcca tttttagcca tgaggatggc
    16081 atctgcttcg atttcagctg cacgaagggc cgctgttgta tctgtcgaga agtatggtga
    16141 accaattcca gcaccaaaga taacgatacg gcctttttca aggtgacgaa gggcacgtcc
    16201 acggacataa ggctctgcca cttgttgcat agcaatagct gtttgtacac gcgtatcaac
    16261 cccaacttgt tgcaatgaat ctgccatcac aagagcattc ataacagtcc caagcattcc
    16321 agtgtaatct gcctgaacac ggtccatacc tgcttctgct gcaggttctc cacgccagag
    16381 atttcctcca ccgataacaa gggcaatttc gatacctaag ctatgaactt cttgaatctc
    16441 ttttgcgatt gtttgaactg tttggatatc aatccctacg ccacgttcac cggcaagggc
    16501 ttcacctgat aacttgatta aaatacgttt atacttggga ttcgccattt tcactctcct
    16561 tctttcatcc tacctatttt atcacaattt ctaagatttt tatagtatca tgaacaattc
    16621 tttcaaaaaa attagacagt caaaaattcc tctaagtcgg caagggcacg ctctgcaatt
    16681 ttttcataac gagccttctt atcacggata cgctcgcctt ccaactcctt gatgatccca
    16741 aaattgacat tcattggttg gaaatgtttg ctgtcggcat gggtaatgta atgagctaag
    16801 cttccaatcg ctgtcgtctc ggggaaaata acctcgcttt cttccttgaa gagacgagct
    16861 gcgttaattc ccgcaactaa gcccgaagcc gccgactcaa catagccttc cacccccgtc
    16921 atctgaccag caaagaagag atttggttgt ttcttggaac ggtaagtctg ctcaagaaga
    16981 tttggtgaat ccatgtaaga attgcgatgc atgacaccat aacggacaaa ctccgcattt
    17041 tcaagacccg gaatcatttg gaagacacgc ttttgttctc cccatttgag gtgggtctgg
    17101 aaaccaacaa tattgtatag gctaccagct gcattatcct gacgaagttg cacaaccgca
    17161 taaggtgttt taaattctcc atcacgaggt cctgtgtagt cgtccggata ctcaagaccg
    17221 actggcttca tagggccata aagcatagtt ttaatgccac gtttggccat aacttcgatt
    17281 ggcatacatc cttcaaagta cttttctttt tcaaaagaat tgagcggtgc ttcttccgca
    17341 ttgaccaagg cttcatggaa atccataaac tcttgcttgg tcattggagc attgagatag
    17401 gctgcttctc ccttatcata acgagatttg agatagacct tactcatatc gatagtgttg
    17461 acatcgataa taggcgctgc tgcatcgtag aaatagaagc catcgccatt attaagggca
    17521 tgaatctttt cagccagggc atcgctagtc aagggaccag tcgccacaac tgtaataaca
    17581 tctgttggca attctgtaat ttcatcacgc accacttcaa tcaaggggtg gttgaccact
    17641 ttttcggtca ccatttgaga gaaaccatca cgatccaccg caagggctcc accggcagga
    17701 acacgtgtag cctcagcaga ttccaagata acagaaccca agcgacgcat ttcttccttg
    17761 agaagaccaa ctgcatttgt caaagcatcc ccacgcaaag aattggaaca aaccaactca
    17821 gcaaaattgt ctgttttatg ctggggtgta gacttgacac cacgcatttc atatagttta
    17881 actggaatac cacgctctgc gatttggtaa gctgcttcag aacctgccaa accagcaccg
    17941 ataacattga tataagattg agacacgaca ctaatacctc tttgggagtg tgaagttaag
    18001 attcacattg aaaaagccaa tcagacttac aagctttcga gtttcttggc tcaggctgaa
    18061 aaagtccaca ggactttttc actcccacaa atctttctat tttttcttct actagtataa
    18121 caaaaaaagg gaagaaggca aacttccctg tttagtcatt ttcttgatgt aaagagatag
    18181 tgagtattcc agttaagaat caattatatg ctactctata aaatcttttc cacataacgg
    18241 atcgataggg actgttattc tatctcttgc tataaccgta ttatctaaaa cagcataaca
    18301 ttcaacatag tgatctcctt taaactgtga atcttcgtga tattttattt tacctgaaaa
    18361 aatagcacca cgctcacaat ttcttctaat agcctcagct tcaatatttc ttactttcca
    18421 atagacttcc tgcgaaa
//
LOCUS       DBERDS010000041        16600 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.041, whole genome shotgun sequence.
ACCESSION   DBERDS010000041 DBERDS010000000
VERSION     DBERDS010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16600
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.041"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     regulatory      72..160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            375..1043
                     /locus_tag="ACL73E_001571"
     CDS             375..1043
                     /locus_tag="ACL73E_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGS0801516.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(1040..1267)
                     /locus_tag="ACL73E_001572"
     CDS             complement(1040..1267)
                     /locus_tag="ACL73E_001572"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801517.1"
                     /translation="MKIKEQTRKLTADCSKHCFEPVDKTDEVSSKHCFEVVDRTDEVS
                     NHTYGKVKLTWFEEIFEEYYLIKFVNIMSLL"
     gene            1370..2152
                     /gene="thiM"
                     /locus_tag="ACL73E_001573"
     CDS             1370..2152
                     /gene="thiM"
                     /locus_tag="ACL73E_001573"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS0801518.1"
                     /translation="MTSLKLLKKKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGMDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            2154..2783
                     /gene="thiE"
                     /locus_tag="ACL73E_001574"
     CDS             2154..2783
                     /gene="thiE"
                     /locus_tag="ACL73E_001574"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS0801519.1"
                     /translation="MFHKELLKLYFICGTTTCQGKDLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      2992..3080
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            3342..3902
                     /locus_tag="ACL73E_001575"
     CDS             3342..3902
                     /locus_tag="ACL73E_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGS0801520.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNMLSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIRLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            3903..5288
                     /locus_tag="ACL73E_001576"
     CDS             3903..5288
                     /locus_tag="ACL73E_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0801521.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEKRNQGRSFLLISHRLDPLISVVDYWIEMTSQGLSHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            5290..5940
                     /locus_tag="ACL73E_001577"
     CDS             5290..5940
                     /locus_tag="ACL73E_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGS0801522.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            5951..6643
                     /gene="tenA"
                     /locus_tag="ACL73E_001578"
     CDS             5951..6643
                     /gene="tenA"
                     /locus_tag="ACL73E_001578"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGS0801523.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            6648..7172
                     /gene="thiW"
                     /locus_tag="ACL73E_001579"
     CDS             6648..7172
                     /gene="thiW"
                     /locus_tag="ACL73E_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGS0801524.1"
                     /translation="MRKHQLQVHKLTILSMMTALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            7172..7975
                     /locus_tag="ACL73E_001580"
     CDS             7172..7975
                     /locus_tag="ACL73E_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGS0801525.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            7968..8600
                     /gene="thiE"
                     /locus_tag="ACL73E_001581"
     CDS             7968..8600
                     /gene="thiE"
                     /locus_tag="ACL73E_001581"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGS0801526.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8810..9601)
                     /gene="thiD"
                     /locus_tag="ACL73E_001582"
     CDS             complement(8810..9601)
                     /gene="thiD"
                     /locus_tag="ACL73E_001582"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGS0801527.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDAYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(9685..9783)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9967..10362
                     /locus_tag="ACL73E_001583"
     CDS             9967..10362
                     /locus_tag="ACL73E_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGS0801528.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     SRLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            10373..10744
                     /locus_tag="ACL73E_001584"
     CDS             10373..10744
                     /locus_tag="ACL73E_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGS0801529.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            10754..12997
                     /locus_tag="ACL73E_001585"
     CDS             10754..12997
                     /locus_tag="ACL73E_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGS0801530.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTTIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFRLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            13204..14979
                     /gene="spxB"
                     /locus_tag="ACL73E_001586"
     CDS             13204..14979
                     /gene="spxB"
                     /locus_tag="ACL73E_001586"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGS0801531.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            15090..15437
                     /locus_tag="ACL73E_001587"
     CDS             15090..15437
                     /locus_tag="ACL73E_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGS0801532.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(15554..16555)
                     /locus_tag="ACL73E_001588"
                     /pseudo
     CDS             complement(15554..16555)
                     /locus_tag="ACL73E_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         4878 a         3056 c         3626 g         5040 t
ORIGIN      
        1 aaagatattt ttcggtcaaa tatcttgcta gggctttcat tttttgctat actggttcag
       61 taattaaata atagagacat ttggggtgct ttaagctgag atgataccca ttgaacctga
      121 tacagttaag actggcgaag ggaaatgtga aacgtttttt cgtatggcga aatgaacgat
      181 ctaatcttgt aagtcaactc taattcttga ttgtaattgg agttttttgt ttatataaac
      241 tggataggct tgtttagtta gctctctgca aatgctctcg atgtgcttta aaaggatcaa
      301 gtggaattac gattttgctt gatatttctt ggtgttttat taattactaa caagtaaaga
      361 gaggagaagt aaatatggaa acacaagact atgcatttca gccaggtttg actgttggag
      421 aattattaaa aagcagtcag aaggattggc aggctgcaat caatcatcgt tttgttaagg
      481 aactttttgc ggggacaatt gagaataagg tcttaaagga ctatctgatt caagattatc
      541 acttctttga tgccttctta tccatgctgg gtgcctgcgt agctcacgca gataaacttg
      601 aatccaagct tcgttttgcc aagcaactag gctttcttga agcagatgaa gatggttatt
      661 tccaaaaggc ttttaaagag ttaaaagtag cagagaatga ctatctagaa gtgactttgc
      721 accctgtaac aaaagccttt caggatctaa tgtattcggc agtggcttca tcagactatg
      781 cccatctttt ggttatgctg gtcattgcag aaggtctcta tttagactgg ggttctaaag
      841 atttggctct acctgaagtc tatattcatt cggaatggat caatctccac agaggtcctt
      901 tctttgcaga gtgggttcaa tttctggttg acgaactcaa tcgtgtcggt aaaaatcgag
      961 aagatttgac agaacttcag caacgctgga atcaagcagt cgctttagaa ttagcttttt
     1021 ttgatattgg ttacgatgtc tagagaaggc tcatgatatt tacaaatttg atgaggtaat
     1081 actcttcgaa aatctcttca aaccacgtca gtttcacctt gccgtaggta tggttactga
     1141 cttcgtcagt tctatccaca acctcaaaac agtgttttga gctgacttcg tcagtcttat
     1201 ctacaggttc aaagcagtgt tttgagcaat ctgcggttag cttcctagtt tgctctttga
     1261 ttttcattga gtataaatca ttcaacgtaa atgaaaaaaa tttcttaacg aaagatagag
     1321 ataaatcgaa atcagtagat cgtataaagt gaaaaggaag gatttcaata tgacaagttt
     1381 aaaattatta aaaaaaaaag caccattggt catttgtata accaatgatg tagtaaaaaa
     1441 tttcacagca aatggattag tagcactggg cgcctcacca gccatgagtg agtttccagc
     1501 agatttagag gatttgttaa agtatgctgg tggtttatta ataaacatag gaacattgac
     1561 agatgaaaat tggaaattat accaagctgc tctgaaaatt gcggagaaat ataatgtccc
     1621 agcagtttta gatcctgtag cctgtggagc aggagaatat agaaaaaaag tagcagatga
     1681 tctaatcaac aattataaac tagcagcgat tagaggaaat gctggcgaga ttgcctcttt
     1741 agtaggaatg gatgtggcat ctaaaggagt agatagtgcg ggcgtagata atattgacga
     1801 aattgctcta gcagcaaatg agaagttcaa tattccaata gtagtaacag gtgaagtgga
     1861 tgccattgct gttaatggag aagtggtaac gattcataat ggtagtgcta tgatgccgaa
     1921 agtcattggg acaggatgct tattaggagc tgtagtagca agctttatcg gacttgaaaa
     1981 aggtcaagaa ttgaaatcat tagaaacagc aatgttggtt tacaatatcg ctggagaaat
     2041 ggcggaaaaa cgtccaaatg gacatcttcc tggaacattt aaagttgaat ttataaatgc
     2101 cttatatgaa attacagatg aagatgtcaa gaaattcaaa agagtgaagt aagatgtttc
     2161 ataaagaatt actaaaacta tattttattt gtggaacgac tacttgccaa ggaaaagatc
     2221 tatatacagt cgttgaggaa gccttaaaag gtggtataac cttatttcaa tttcgagaaa
     2281 aaggtgaggg tgctttagaa ggcttagaaa aacttgagct agctatccaa attaaagaac
     2341 tttgtaaaaa atacaatgtt ccatttatcg ttaatgacga tatagattta gcaatggaaa
     2401 ttgacgccga tggcgtacat gtaggtcaag atgatattgg tgttgatgaa attagaaaat
     2461 tgatgccaga taaaataatt ggtctttcta taaaaaacga ggaagaattt caacaatcaa
     2521 aagttgaata tgtagattat gtaggtgttg ggcctgtatt tgatacccag tcaaaagatg
     2581 atgctggtgg tgctataggt tatgaaggtc ttgaattgat gagaaaacta ttgccacaaa
     2641 tgcctttagt tgcaattggt gggatacaga cgaaacatat taaagacatt ataaagacca
     2701 atgttgacgg cgtttcaatc atttcggcaa tatcgtatgc aaaaaatata gaaaaaactg
     2761 ttcgggaaat gagtgaacaa tagatatcta tccttggatt ctaagtaagt aggattttcc
     2821 ttttttaaaa agctatgtct agattcagct tgaatggcta attcatcaaa caggtcattt
     2881 gttttttgca aaagaaagat ctgctgtctt tgtgagtgca aggctgtatt tccagttcaa
     2941 tttcttgaac tagtataaaa tgtgtgttat aataattaca taattaaata ataaaggcat
     3001 ttggggtgct ttaggctgag atgataccca ttgaacctga tacagttaag actggcgaag
     3061 ggaaatgtga aatgtttttt tcgtatgtcg aaaagaactg tctaatcttg taagctgaac
     3121 tctaattcgt atctgtaatt agagtttttt cttttacgaa actggatgaa gatgatatag
     3181 tagattgaaa taagatgcga acaaatcaat tagaaaattc aaattaattt ctagaaatat
     3241 tttagcattc ctgtgtactg ttctaaattc aatctgctat acaaagtatt taggtcggtc
     3301 ttcttgagtg ccccactttt cttttaaaaa aggagttttt tatgttgaaa aaatggcagt
     3361 taaaagatgt tatcttgctt gctttcttgt ctatcttttt tggtggggtt ttcgttggtt
     3421 caggatatgt gtataatatg ctcagtctac tcttaacacc tcttggtttg caggcctttg
     3481 ccaatgaaat cctcttcggt ctctggtgta tggctgcgcc cattgctgcc atctttgttc
     3541 cgagagtcgg aagtgcaacg attggagaag tgctagctgc gcttgctgaa gtcctttatg
     3601 gtagccaatt tggtctagga gctcttttgt ctggcttggt tcaaggtttg ggaagtgaat
     3661 ttggttttat cgtaactaag aatcgctatg aaagttggct ctctctaact gctaatagta
     3721 ttgggattac gcttgttagc tttgtctatg aatacattag gttaggttac tacgcctttt
     3781 cccttccgtt tgtcctttcc ttacttgtgg tacgttttat ttctgtttat ttcttctgta
     3841 ccatcttggt tcgtgccatt gtcaaactct atcatcagtt tgcaactgga ggaaaagcat
     3901 agatgggtct ggaactacga gcgattcagt ccccaatctt ctctgagccg tttgatttta
     3961 cttttcatgc gcaagccttt accttgttag ttgggagtag tggttcagga aaatccagcc
     4021 tttttcaagt cattgcccaa gtcagttctc ttccctatag tggtcaagtc ctgatagatg
     4081 ggagcgaggt cagtcagctt tctatcatcg cacgtgtcca gaaggttggc attctctttc
     4141 aaaatcccaa tcatcaattt accatggaga acttgtttga ggagctgatt ttcaccttgg
     4201 agaatatcgg ctatcacctt caggaaattg attctaaaat agcagaggtt gtccagcaat
     4261 gtcgttgcga ggcaatctta caccgtccca ttcatcacct atcaggtggg gaaaagcaaa
     4321 aagcagcgct ggctgtcctc tttgccatga atcctagggt ctatctcttg gatgagccct
     4381 tcgcttctat tgaccgcaag agcagaatcg agatattgga gattctaaaa gagttggctc
     4441 ttgatgggaa gacagttatt ttgtgcgacc atgatttatc tgactataaa gcctatatcg
     4501 accatatggt tgagctaaga gacggaaaac taagggaagt gtttcaaatc ccttcctatg
     4561 agatgacaca ggttgcttca aaggaagttg cttctagccc ggaactattc catatgaacc
     4621 gtgtgactgg tgagcttggt aatcgccccc tcttttcaat tgctgatttc acattctatc
     4681 aagggatttc ctgtatcctg ggtgacaatg gtgtcgggaa atcaaccctc tttcgctcta
     4741 ttcttcaatt tcaaaagtat aaggggcgca ttgcatggaa ggggacagtc ctgaaaaaga
     4801 aaaagagttt gtaccgtgat ctgacgggtg ttgttcagga agctgagaag cagtttatcc
     4861 gagtaagtct gcgagaggag cttcaattag atggacctga ttctgaaaga aatcagcgga
     4921 tttttcaagc tttacgatat tttgatttgg agcaggcagt cgataagagt ccctatcaat
     4981 taagtggtgg tcagcaaaaa attcttcagc tcctgaccat cttgaccagt aaggcttccg
     5041 tgatcttgct agatgaacct tttgcaggtt tggatgatag agcctgccat tatttttgca
     5101 agtggattgt ggagaagagg aatcaaggaa gaagttttct gctcattagt catcgtttag
     5161 accctttgat ttctgtggtt gattattgga ttgagatgac tagtcagggg ctcagtcatg
     5221 tgaaagaagt gaccattacc aaaccactta catctcagag tagcaatacc caaggggagg
     5281 tgagatagta tggtcaaagt agcaacccag acaccgatta tcagtctctt cttgctgatt
     5341 ttatccttgg aaacatcttt cattccttcg attgctctga atctttcggt agtcgcattt
     5401 tgtattctct ttatgctcta ttaccgtcga tttaaaatgt tagcttggat gatcatactt
     5461 gccattttac catcttttgc caactactgg gcagttcagt tacacggaga tgcttcacag
     5521 gcagtcatgc ttggaacgag ggcctttgtg acagtttgta tcggccttgt ctttgtttcc
     5581 tctatttcac taaaagagct tctcttgtac ttggctcaaa aggggctatc acgctcttgg
     5641 tcctatgcct tgattgtggt attcaattcc tttcctctca ttcagcaaga aatcaagtcc
     5701 ctcaaagaag cttgcctatt acgtggtcaa gaactgcatt tttggtcgcc cttgatttac
     5761 agtaaggttc tgatgacagt ctttaggtgg cgccatcttt acctgagagc tctgtctgct
     5821 catggatatg acgaacatgc acagttgaag aatagctatc ggacttttta tattcctaaa
     5881 aaaacaaaat taatctacct gcttttcttt ttattgcttc aaaccagtct atttttataa
     5941 aggagttatt atggaattta cagatattgc gatggaatta tccaagaaag cttggcaggc
     6001 ttcctttcat catcccttta ttttacaatt acaagagggg aatttagaac ctgccatttt
     6061 ccgctattac ctgattcagg atgcctacta tctgaaggcc ttctcagaaa tctatcatct
     6121 tttggctgat aagacttcaa accaagagat gaaaagactc ttgaaacaaa atgctcaggg
     6181 tttagtggag ggtgagttat ttattcgcca acaatttttc aaggaattgg aaatcaacga
     6241 ccaggaaatg gagcaacatc caatcgctcc aacctgttat cattacattt ctcatattta
     6301 taggcaattt gcagaaccga acttagccat cgcttttgca agcttgcttc cttgtccttg
     6361 gttataccat gatataggca aatcacttaa tcttaaacca tcaccaaatc ctctctatca
     6421 acaatggatt gaaacttata ttacggatga gttagagcaa cagatcagag aggagggagc
     6481 actggtcaat cagctctatc gagaaagtga tgagacagat aagcaaaaaa tgctagatgc
     6541 cttccacatc agtgttcata tggaagccaa gttttgggag atggcttacc aacaccagac
     6601 atggaagagc gatttacagt ctttagaaaa aggagaagaa tagaaacatg agaaagcacc
     6661 aactacaagt tcacaaattg accattttat ctatgatgac tgcccttgat gtagtcctta
     6721 cacctatctt tcggattgag ggaatggcac cgatgtccag tgtagtcaat attctagcgg
     6781 gaatcatgat gggacctgtt tatgccttgg ccatggctac agtgacagcc tttatccgta
     6841 tgacgactca agggattccg cctttagctc tcacaggagc gacttttgga gcccttctag
     6901 caggtctctt ttataagtac ggtcgaaaat tttacttttc tgccttggga gaaattgtgg
     6961 gaacaggtat tattggttct attgtttcct atcctgttat ggtactcttt acaggatcag
     7021 ctgctaagct tagctggttt atctacacgc ctcgattttt cggagcaacc ttgattggta
     7081 cagcgatttc ctttattgcc tttcgatttt taatcaagca ggaattcttt aaaaaagtgc
     7141 agggatattt ctttagtgaa aggatagact gatgcaggaa tttacaaatc cctttcctat
     7201 aggctctagt tccctcattc actgtatgac caatgagatt tcttgtgaga tgctggcaaa
     7261 tgggattttg gctctgggat gcaaacctgt catggcagat gatccccgtg aggttcttga
     7321 ttttactaag caaagtcagg ctctcttcat caatttgggg catttgtcag ctgagaagga
     7381 gaaagcaatc cgtatagcag cttcttatgc agctcaagtt tgtctcccaa tggtagtaga
     7441 tgcggttggc gtaacagctt catccattcg taagagctta gtcagagacc ttttagacta
     7501 tagacctacg gtccttaaag gaaacatgtc agaaattcga agtcttgttg gattaaagca
     7561 ccacggcgtt ggggtcgatg cgagtgctaa agatcaagaa acggaggatt tgcttcaagt
     7621 cttgaaagac tggtgtcaga cctatcatgg tatgtctttc ttagtcacag gtcccaagga
     7681 cctcgtcgtt tcgaaaaatc aggtcgctgt actgggaaat ggctgtgcag aattagactg
     7741 gataacaggg acaggagatt tggttggagc cttaacagcc gtttttctca gccaaggaaa
     7801 gactggtttt gaagcttctt gcttagcagt ctcttatctc aatatcgctg ctgagaaaat
     7861 agttgttcaa ggaatgggat tggaagaatt tcgttaccaa gtactcaatc agctttcgct
     7921 cctaagaaga gatgaaaatt ggctagatac catcaaagga gaggtttatg aatagagaag
     7981 cacttagact atatctggta accaatcgct atcaagattc cgtggaaagc tttcttgcaa
     8041 aagttgagac ggcctgccgt tcaggggtta ccatagtcca attgcgagaa aaaaatctca
     8101 caaccaatca atattatcaa ctggcaaaac aagtcaagga aataacagat gcttatcagg
     8161 tacccttgat aatcgatgat cggttggatg tttgtcttgc ggttgatgct gctggtctgc
     8221 atattggaga tgacgaactc ccagtttcgg ttgcccgaca agtcttgggt cctgaaaaaa
     8281 tcctcggtgt caccgctaaa acggttaaaa gagctctgga agcggagaaa tcaggtgcag
     8341 attacttggg tacaggagcc attttcccaa ccaccaccaa ggaaaatgcg cccattactc
     8401 tgatatcgac cttgaaaaca atttgccaaa cggttgccat tccagtagtt gctattggag
     8461 gcttgacttc ggagaatatt gatcagctta tgggcactgg catagctggt gtagctgttg
     8521 tacgtgattt gatgcaagca gaagatattg aggcaaaaac gcaagccttt ttaacaaagt
     8581 tgcatgacat tctttcctaa ttaatactca atgaaaatca aagagtaaac tagaaagcta
     8641 gtcgcaggtt gctcaaagta ctgccttgag gttttagata agactgacga agtcagctca
     8701 aaacagtgtt ttgaggttgc agatggaagc tgacgtagtt tgaagagatt ttcgaagagt
     8761 ataaaaactc tctaattccc ttaaagtggg aactagagag ttttttttct taatctttaa
     8821 aagttgtatg gttgactgga ccagaaccat gaccgagttg aggggcatct tgaatagctt
     8881 ttgtgataaa ggccttggcc ttatcaactg cctggtaaag actcttgccc ttggctagtt
     8941 cagcagtaat cactgcagca aaggtacatc cagtaccatg ggtgtgacag gtttgaattc
     9001 gtgggctttc ccagacaaat tgttcattct tggtaaagag gaaatcttta gcaccacctt
     9061 tgagatgtcc gcctttgata accacagact gaggaccaaa ttcttttaaa atcaggcgac
     9121 cagcacgctg catgtcttcg gggtcatgga ttgaaaaacc aacaatctct tctgcttcag
     9181 gaagatttgg cgtaataata gttgctagag gtagtaagtt tgttttgaga tagtctctag
     9241 cacttgagtc aatcaaggca tctccacttg tagcaaccat aacaggatca aggacatagg
     9301 gacaatccag ttttttaaga tagggttgga tgatttccat gatttcagta gtagccaaca
     9361 ttccagtttt tacagcctga ggtggaatat cagaaaagac actgtccaat tgggctttca
     9421 acatttgagg agaaacgtgt tcgattagct gaacacctct ggtattttga gcgacaagac
     9481 tggttacaac agccattcca taggcatctc tcgcttggaa tgactttaaa tctgccataa
     9541 tgccagcacc accactaggg tcagtccctg caatggtcaa agcaacgggt aaataagtca
     9601 tctaaaacct cccaaccaac tgaagtttgt attcttaaga acaagctagt ctgttttaga
     9661 aaggcaatag aagactgcta gtccccatta tcatttccac ttccatcagc tagcattacc
     9721 tagattgagt cagagggatc taacagtcgt taatctcagc tttacgcacc cctagtggtt
     9781 gttttctttt ttctttagta tagcatattt ttattgttta tatagtaata tttgactgca
     9841 aatcgttttt caaatgatta aaattctatt tttcgaagaa aatattattt ctataattga
     9901 caaatgtaga ttttgagagt atactgatga gtgtaattga caaatgtaga ttttggaggt
     9961 atggtaatgc agatttcaga tgcagaatgg caggtcatga agattatttg gatgcagggg
    10021 gagcagacca gtacagattt gattagggtt ttggcagagc ggtttgattg gtccaagtca
    10081 acggttcaga cacttttgtc tcggctggtt gagaaagagt gtttgactcg gaaaaaagaa
    10141 ggcaagtcct ttgtttattc agccctttta actctagacc aaagtcggga tttacttgtc
    10201 caagatatca aagacaaggt ttgttcccgt aggattagga atttgttggc tgacttgatt
    10261 gtagaatgtg aatttactca gactgacttg gaagacttgg aagctgtgat ttcagagaag
    10321 aaatcaagtg ctgtaacaga agtaagatgt aattgtatgt aaaggagacg tcatgttaaa
    10381 tagtattgta accattattt gtattgccct tatcgcgttt atcttgtttt ggtttttcaa
    10441 aaagcctgaa aaatctggac aaaaagccca gcaaaaaaat ggataccaag agattcgagt
    10501 ggaagtcatg ggaggctata ctcctgagtt gattgtcctc aagaaatcag tgccagcacg
    10561 cattgtcttt gaccgcaagg atccttcacc atgtctggat caaattgttt ttccagattt
    10621 tggtgtacat acgaacctgc caatggggga agagtatgta gtggaaatca cgcctgagca
    10681 ggctggagag tttggctttg cttgtggtat gaacatgatg cacggcaaga tgattgtaga
    10741 gtaggtggag actatgacag aaattgtgaa agcaagctta gaaaatggca ttcaaaaaat
    10801 ccgtatccga gctgaaaaag gctatcatcc agcccatatc cagcttcaaa agggaattcc
    10861 agctgagatt acctttcatc gtgctactcc ttcaaactgt tataaggaaa ttctgtttga
    10921 agaagaaggt atcttggaac caatcggcgt agatgaggag aaagtcattc gttttacacc
    10981 tcaagaatta gggcgacatg aattttcttg tggcatgaag atgcaaaagg gaagctatac
    11041 agtcgttgag aagactcgaa aatctctatc tctcctgcaa cgtttttgga ttactagtat
    11101 ctttactgtg cctcttgtga ttctcatgat tgggatgttg acaggtagca ttagtcatca
    11161 agtcatgcat tggggaacct ttctagcaac aacgactatt atgttagttg caggtaagcc
    11221 atatatccag agtgcttggg ccagttttaa aaagcacaat gccaacatgg ataccttggt
    11281 tgcgctggga actctagtgg cttatttcta tagcctagtt gctctctttg ctggtctccc
    11341 tgtttacttc gaaagtgctg gatttatcct ctttttcgtt cttttgggag cagtttttga
    11401 ggaaaaaatg agaaaaaata cgtcccaagc tgtggagaaa ttactggact tgcaagctaa
    11461 aaccgcagaa gtcttgagtg atgatagtta tgtccaagtt cctttggaac aagtcaaggt
    11521 aggcgacctg attcgagtgc gtcccggtga aaagattgct gttgatggtg tcgtagtaga
    11581 aggtgtctct agtattgacg aatccatggt gacaggtgag agtctgcctg tggacaagac
    11641 agttggagat actgtcattg gctcaaccat caatcatagt ggaacgcttg tctttagagc
    11701 agaaaaagtt ggctcagaga ctgttttggc tcagattgtg gattttgtga agaaagctca
    11761 gacaagtcgt gcgccgattc aagacttgac ggataagatt tcagggattt ttgtcccagt
    11821 agttgtcatt ttaggaatca tgaccttttg ggtttggttc gtcttgctca gggatagtgt
    11881 ggttgtgctt ggagctagct ttgtgtcctc tcttctctac ggagtggcgg ttttgattat
    11941 cgcctgtcct tgtgccttgg gacttgcaac accgacagcc cttatggtgg ggacaggacg
    12001 tagtgccaag atgggggttc tcctcaaaaa tggaactgtc ttacaggaaa tccagaaagt
    12061 tcaaaccctt gtctttgata agaccgggac tttgacggaa gggaaacctg tggtaacaga
    12121 tgtcatcggc gacgaagtag aagtgtttag gttggcagcc tccttggaag atgcttctca
    12181 acacccactg gctgaggcta tcgttaagcg agcgagtgaa gctggacttg agtttcaaac
    12241 tgttgaaaat tttcagacct tgcacgggaa aggtgtttca gggcgaatca atggaaaaca
    12301 agttttactt ggaaatgcta aaatgctgga tggcatggat atttctaata cttatcaaga
    12361 taaactagaa gaactagaaa aagaagctaa gacagttgtg ttcttagctg ttgacaatga
    12421 aatcaaaggc ttgcttgctt tgcaagatat tcctaaggaa aatgctaagc tagccatcag
    12481 tcagctaaaa aaacgtggtc tccgaacagt catgctgaca ggagacaatg ctggtgtggc
    12541 gcgtgctatt gcagatcaaa tcggaattga agaggtcatt gcaggcgtct tgccagaaga
    12601 aaaagcccat gaaatccata aactgcaaca gtcagggaaa gtagcctttg ttggggacgg
    12661 tatcaatgac gctcctgccc ttagtgtagc agatgtgggg attgctatgg gagctggaac
    12721 agatatcgcc atcgagtcag cagatttggt gttgacaacc aataatcttt taggagtggt
    12781 tcgtgccttt gatatgagta agaaaacctt tcatcgaatt ctactcaatc ttttctgggc
    12841 ttttatctac aatgttgtcg gaattccgat tgcagcagga gtcttttcag gtgttggact
    12901 ggctctcaac ccagaattgg caggtctagc catggccttt agttctgtat ctgttctgac
    12961 cagttccctt ctgttaaatt ttagtaaaat agactaaaag taatgactag atttctttgt
    13021 tataaaacag aaatgacaga actttcaaaa ctgtattaga atagagaata gagagttttg
    13081 agcagatttt tagaaaagtc agcataaata tgatacagtg gaatagtaaa aatttggaga
    13141 acgtttccaa ttctatgtaa tcgtattctc caaatctaaa aaaattgaag gagagttatc
    13201 attatgactc aagggaaaat tactgcatct gcagcaatgc ttaacgtatt gaaaacatgg
    13261 ggcgtagata caatctacgg tatcccatca ggaacactca gctcattgat ggacgctttg
    13321 gctgaagaca aagatatccg cttcttacaa gttcgccacg aagagacagg tgctcttgca
    13381 gcggttatgc aagctaaatt cggcggctca atcggggttg cagttggttc aggtggtcca
    13441 ggtgcgactc acttgattaa cggtgtttac gatgcagcta tggataacac tccattccta
    13501 gcgatccttg gatcacgtcc agttaacgaa ttgaacatgg atgctttcca agagcttaac
    13561 caaaacccaa tgtacaacgg tatcgctgtt tacaacaaac gtgtagctta cgctgagcaa
    13621 ttgccaaaag taattgacga agcctgccgt gctgcaattt ctaaaaaagg tccagctgtt
    13681 gttgaaattc cagtaaactt cggtttccaa gaaatcgacg aaaactcata ctacggttca
    13741 ggttcatacg aacgctcatt catcgctcct gctttgaacg aagttgaaat cgacaaagct
    13801 gttgaaatct tgaacaatgc tgaacgccca gttatctatg ctggatttgg tggtgttaaa
    13861 gctggtgaag tgattactga attgtcacgt aaaatcaaag caccaatcat cacaactggt
    13921 aaaaactttg aagctttcga atggaactat gaaggtttga caggttctgc ttatcgtgtt
    13981 ggttggaaac cagccaacga agtggtcttt gaagcagaca cagttctttt ccttggttca
    14041 aacttcccat ttgctgaagt ttacgaagca ttcaagaaca ctgaaaaatt catccaagtt
    14101 gatatcgacc cttacaaact tggtaaacgt catgcccttg acgcttcaat ccttggtgat
    14161 gctggtcaag cagctaaagc tatccttgac aaagtaaacc cagttgaatc aactccatgg
    14221 tggcgtgcaa acgttaagaa caaccaaaac tggcgtgatt acatgaacaa actcgaaggt
    14281 aaaactgagg gtgaattgca attgtatcaa gtttacaatg caatcaacaa acatgctgat
    14341 caagacgcta tctactcaat cgacgtaggt aacactactc aaacatctac tcgtcacctt
    14401 cacatgacac ctaagaacat gtggcgtaca tctccactct ttgcgacaat gggtattgcc
    14461 cttcctggtg gtatcgctgc taagaaagac aatccagatc gccaagtatg gaacatcatg
    14521 ggtgatggag cattcaacat gtgctaccca gacgttatca caaacgttca atacgacctt
    14581 ccagttatca accttgtctt ctcaaatgct gagtacggct tcatcaagaa caaatacgaa
    14641 gatacaaaca aacacttgtt tggtgtagac ttcacaaacg ctgactacgc taaaattgcg
    14701 gaagctcaag gagctgttgg attcacagtt gaccgtatcg aagacatcga tgcagttgtt
    14761 gcagaagctg ttaaattgaa caaagaaggt aaaactgttg tcatcgatgc tcgcatcact
    14821 caacaccgtc cacttccagt agaagtactt gaattggatc caaaacttca ctcagaagaa
    14881 gctatcaaag ccttcaagga aaaatacgaa gcagaagaac tcgtaccatt ccgtctcttc
    14941 ttggaagaag aaggattgca atcacgcgca attaaataat tcctctcgcc gaaaatcaaa
    15001 tatgaaactt gtagacttta ttctttgatt ttcatagagc agaactttaa aagatcggag
    15061 caatccggtc tttttatgga ggagagtaaa tgaatttaaa tcaattagat attatcgttt
    15121 caaatgttcc ccaagtctgt gctgacttgg agcatatttt ggataaaaag gcagattatg
    15181 ctgatgatgg ttttgctcag tttacgattg gtagtcactg ccttatgttg tcacaaaatc
    15241 atttggttcc tttggaaaac tttcagtcag gaatcattat tcatatcgag gttgaggatg
    15301 tagaccagaa ctacaaacgg ttgaacgagc ttggtataaa ggttttacac ggaccaactg
    15361 taaccgattg gggaacagag tccttattag ttcaaggacc tgctggtcta gtgcttgatt
    15421 tttatcgtat gaaataggtc gcgtagtcat ttgacgttaa ccttagctat ttttaaaata
    15481 gaaattgaga atatgaacta ttgaaagatc ggagcaatcc ggtcttttta tataaagaaa
    15541 ttgcatataa tactcatctg ctttcaaaaa gcattctagt ccatctccga ttaacgatgg
    15601 actttatcac ctccttctcc aatccttgta tgacatcttg aagttgattc atgacatctt
    15661 ccaaagttcg aaaggcctta ttcttaaatc cacgtttacg aatctctttc cacacttgtt
    15721 caatgggttc atctctggtg tgtatggagg aataaaggta aaaccaatat tagtcggaat
    15781 ctttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa gataatcatc
    15841 tggataagct tgtgaaagct cttctaaaaa ggcgttcatc cactcagtat tacatccacc
    15901 agctattaag aaaaatgatt cgcctgtatg ggcatcaaca gctccataac aatagtgaaa
    15961 ttctcgtata tagtgactat ggacatgtgg acctactcct attggagccc aacaagatcc
    16021 cagtttactg attctaccga aaccagcctc atcttggtac atcaagcgaa ccttacgaaa
    16081 acgtctactg cttttaaagc gctttctttt cttcttgaat tgagatttta tttttagacg
    16141 cgacaatggt ttgagcgtct gctttcctag gatgttctgg acgtggcata atatttcgcc
    16201 aaccatggtg cttcaacagt tgatagaagg catcacgtgt gtaggaacga cctaactcct
    16261 ttttataagc ctgaaataag gcatcaattg taacaaattc tcctgcctct gtagccttca
    16321 aatggcgggc aagaaagact ttcttttcct caatcgtcat atatgcatgg ttacggccac
    16381 cacgtgtttc ttgaaggaga gagtcgagtt cgaactcctc atattttttt acatttcgcc
    16441 aaatcgttgt ttgattacag tctatagtgt attgaatcta taacagtaca ccttagctgc
    16501 taaaatattt ctataaatta gtttgacttt cctgatagag ttgttcacat cttatttcaa
    16561 actactataa aagttctata atctctttat aagatttgcc
//
LOCUS       DBERDS010000042        16373 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.042, whole genome shotgun sequence.
ACCESSION   DBERDS010000042 DBERDS010000000
VERSION     DBERDS010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.042"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            45..359
                     /locus_tag="ACL73E_001589"
     CDS             45..359
                     /locus_tag="ACL73E_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGS0801533.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIATAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            477..2456
                     /locus_tag="ACL73E_001590"
     CDS             477..2456
                     /locus_tag="ACL73E_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0801534.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            2466..2780
                     /locus_tag="ACL73E_001591"
     CDS             2466..2780
                     /locus_tag="ACL73E_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGS0801535.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            2811..3317
                     /locus_tag="ACL73E_001592"
     CDS             2811..3317
                     /locus_tag="ACL73E_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801536.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            3397..4743
                     /gene="celB"
                     /locus_tag="ACL73E_001593"
     CDS             3397..4743
                     /gene="celB"
                     /locus_tag="ACL73E_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGS0801537.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            5123..5299
                     /locus_tag="ACL73E_001594"
     CDS             5123..5299
                     /locus_tag="ACL73E_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801538.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            5709..7922
                     /locus_tag="ACL73E_001595"
     CDS             5709..7922
                     /locus_tag="ACL73E_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGS0801539.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(8144..8620)
                     /locus_tag="ACL73E_001596"
     CDS             complement(8144..8620)
                     /locus_tag="ACL73E_001596"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGS0801540.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            8843..12043
                     /locus_tag="ACL73E_001597"
     CDS             8843..12043
                     /locus_tag="ACL73E_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGS0801541.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            12423..12799
                     /gene="tnpA"
                     /locus_tag="ACL73E_001598"
                     /pseudo
     CDS             12423..12799
                     /gene="tnpA"
                     /locus_tag="ACL73E_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            12981..13043
                     /locus_tag="ACL73E_001599"
                     /pseudo
     CDS             12981..13043
                     /locus_tag="ACL73E_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13187..13816)
                     /locus_tag="ACL73E_001600"
     CDS             complement(13187..13816)
                     /locus_tag="ACL73E_001600"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGS0801542.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(13826..14827)
                     /locus_tag="ACL73E_001601"
     CDS             complement(13826..14827)
                     /locus_tag="ACL73E_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGS0801543.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(14858..15499)
                     /locus_tag="ACL73E_001602"
     CDS             complement(14858..15499)
                     /locus_tag="ACL73E_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGS0801544.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(15518..16333)
                     /locus_tag="ACL73E_001603"
     CDS             complement(15518..16333)
                     /locus_tag="ACL73E_001603"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGS0801545.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         5268 a         2659 c         3405 g         5041 t
ORIGIN      
        1 acttagcaca gctttgattg gatttaagaa aaggagaaaa tattatggca aaagctttaa
       61 ttatttgtgc agcaggaatg tcttcatcac ttatggcaca gaaaacaaca gagtttctaa
      121 aaggaaaagg gaaagatatt gtagttgatg ctattagtgc tactgaagga gggaaagcta
      181 tcgcaacagc agcttttgat ttgtatcttg tcagtcctca aacaaaaatg tactttaagc
      241 aatttgaaga ggctggttct aaagcaggaa aaccagttgt acaaatacct cctcaagcct
      301 atattcctat tccaatggga attgaaaaaa tggctaattt gattcttgag aatatttgat
      361 gaacacatga aatgtcaata aatatttaag ttaagataaa ttgttttgag tttgatataa
      421 attgatttaa gtgtataata tgcttcaata tatgaaaaca tacgttttag gagggaatga
      481 atgtgttaaa cattaaagag aaagatatcc ttcaattttt aataaaaaat aaggaacgtt
      541 ttgttacaag caaagaactg gcagaatatt tatcctgttc agatagaact gtccgtaatg
      601 tactgaaatt aattgagaag acaatgatta ttcaaggagt ccggttgatt tcaaaacaag
      661 gtcaagggta tcaaatattt tttgagaatc aaggcgctta ccaggagttt agacaaactt
      721 atgaactgga agaagactat acgaaaactg cggtttcaaa aggtgatgat cgtttagtat
      781 ttatcttaaa taaattatta tttgagcaag ttccagttct ttttgatgat ttagctgatg
      841 aactttacgt tagtcgttca acattatctc atgatttcag aaagatacga gtgatgttat
      901 cagagtataa tttgtccatt gagagtaggg cgaataaagg agtttatgtc tcaggcgagg
      961 aacgtgataa acgacgtttt atcataaatt atttcctaga gaatcaattt tttaaaacaa
     1021 tacattgcta tgtaaaattt aacttttttg ctcaaactgt tccattagaa gaatttgcta
     1081 gaattgtttt ggatgaatgc caagaggcca acctaaaact atctgatttt gtactacaga
     1141 atttagtagt tcacatagca ttgtctgtga ttcgtttaaa atccggattt gaaataaaaa
     1201 atatagactg tcagatgact gatgatgcaa tagagagaaa ggttgctcaa agaattcttt
     1261 ctaaagtaag agaagtaaca aatcaggaat ttccagttca ggaaatagac tacattactt
     1321 tgcatttgtt agctaagagt caacaatgtc aaaaaaatca gaagaatatt tctgaagaag
     1381 ttttaaaaaa atctttattt aaaacatttc agaatttagg attagatgat atgtataact
     1441 tttcttcaga tttccaacta attgaaggat tgataactca tctaatgaca ctacaagtac
     1501 gtttagaaag ccggattacc ttaaataacc ctttggtaga tgaaattaaa cagaattata
     1561 gtgatatatt ctttatgact agagaaattc ttgcaaatat ggacaagttc ttggagtgga
     1621 caatatcaga tgatgaagta gcatatgtaa gtcttcactt tttagctgct atggaacgta
     1681 gcaaagagag tactaagttt aatattcttg ctatttgtgc aacaggattt ggtgcagccc
     1741 aaatgttaag aaatcgtttg gaaacggagt ttgggaagcg agtagaagtt gttgatgtaa
     1801 taggctatta tgaattgaat caagaaaaac ttaaaggaat agattttata gtgtcagctg
     1861 ttgatttatc aaatctatat tttcaaattc cagtttttaa agttagtgtg tttcttaaga
     1921 gtgatgagat ggaaatgatt agaaaagcta tggatcagat gcaagtttct agttatgtac
     1981 aatcatcaaa gattaataaa tttgaaaaca acagctttag acagtatttt agtaaagaaa
     2041 attttttaat atgtactgaa tcagacaagg taaatttact tgaaaagatg gttgagagtt
     2101 tatctgttgg tgaatcaaat gagtttgaac aatctttact ttatggaatt aaacagcgcg
     2161 aagaattaag ttcagttgtt ttttctgaaa aaattgcagt tccgcatcct attcagccct
     2221 ttggtacaga gggaaaggtt tcggttgcaa tctgtaaaga ttcgttactc tgggataatc
     2281 aaagttcata tgtccagcta gtatttcttc tatctccatc aatatatggg aacgaaggtt
     2341 tggcaactgt gactaaaaag atagtctctc tgacagagaa tgatgagttg caaaatcagc
     2401 taatatcttg caataacttt gaagatttta ttagcatatt tgagaagata aaataggagg
     2461 ttcatatgaa tcaagaggaa ctgcaggttg cagcatttga aattatcctg cattcgggaa
     2521 atgcaaggtc agaaatacat gaagcatttg caaaaatgag agaaggtagt tttgatgatg
     2581 cagaaagtaa attaaatcaa tcaaatgaga taattcttga agcgcatcat gcacaaacca
     2641 aactcttgca agaatacgca agtggagtgg aaattaaaat tgaaattatc atggtacatg
     2701 ctcaagatca tttaatgacc actatgacat tattagaagt agcaaaggaa atgttagctc
     2761 tttataagaa agttaactaa atatgtgttg ttatataagg aggaaatgat atggataaaa
     2821 aagaacgaca aaagattgaa caacaacgtc gagagatggc tctaactaat acttttttta
     2881 atcgatatct tcttctacgt tattcaatag cactcttctt ttttgggaat atttattggc
     2941 ttttgaatca gtttattaat ccctcgccta ttattatttt ccccattatg ctcatagtat
     3001 tttctatttt agcaactgtt gaacaattta aactctatgg aaataggaaa gaaaagttgg
     3061 gaataacact aatgtttgtt agaatacaaa tacttatttc aataggatta cttgttttaa
     3121 cttggacaag ttggtttaag aatctttttc cgatttttga aaataaccaa gtagcacgtt
     3181 tatttgtttt tgtagttctt ctattaggtt tagttctgag tttgttagac attagaagaa
     3241 ttaaaaaaat ttataaacga acagataagg cttatcaaca atttgtccaa ttggaaaaga
     3301 actcacttag tttataatcc tgatctagta taatttgtat ttgaaactag tctttagaaa
     3361 gtaaaaatta ttatgtttta ttaaggaggt ctatttatgg atcaacaaaa cgggttgttt
     3421 ggttttcttg aaaaccatgt tatgggacca atgggcaaac ttgctcagtt taaagtagtg
     3481 cgtgctatca cggctgcagg tatggctgct gtaccattta ctattgtagg atcaatgttt
     3541 ttggtattca gtattttgcc acaagctttc tcattttggc caattgtggc agatattttc
     3601 tctgcttcat ttgataaatt cacatcactt tacatggttg caaactatgc gactatgggt
     3661 tctctatctc tttatttcgt tctatcactt gcatatgaat tgacaaaaat ttatgcagag
     3721 gaagaagaac tcaatatgaa tcctcttaat ggtgccttgc tcgccttgat ggcttttgtc
     3781 atgacagtac cgcaaatcat ttttgatggt ggaatgatga agactgtgac aagtctaaaa
     3841 gaaggtgcag taattgcaga tggatgggca atgggaaatg gagtcgcacg ttttgggaca
     3901 acagggattt ttaccgcaat cattatggca attgtgactg ttcttattta tcgtatgtgt
     3961 gttaaacata attgggttat taaaatgcct gaagctgttc cagaaggagt ttctcgtgga
     4021 tttaccgctt tggttccggg atttgttgtt gcatttgttg ttatctttat caacggtctt
     4081 cttgtagcaa tgggaacaga tatttttaaa gtcattgcaa ttccatttgg ttttgtatcc
     4141 aatctgacta attcgtggat tggtttaatg attatttatc tattgactca actactttgg
     4201 attgtaggta tccacggtgc gaacattgtt tttgcatttg ttagtccaat tgctcttgct
     4261 aacatggctg aaaatgctgc tggcgggcac ttcgctgttg caggtgaatt ttctaatatg
     4321 tttgtaattg caggtggttc tggtgcaact ttaggactat gtttatatat tgcttttgcc
     4381 tctaaatctg aacagcttaa agcaatagga cgagcatctg tagttccagc cttatttaat
     4441 attaatgaac cattaatttt tggattacct attatctata atccagcctt ggctatacca
     4501 tttattttag caccaatggt tactgctact atttattacg tagcgaattc tctaaacttt
     4561 attaagccaa ttatcgcaca ggttccatgg ccaactccag tagggattgg agctttctta
     4621 gggacagcag atcttcgagc tgtattagtt gctctagtat gtgcatttgc agcattctta
     4681 gtctatcttc cattcatccg tgtatatgat caaaaattgg tgaaagaaga gcaaggtatc
     4741 taataagtaa aaaagtatac tcgatgatag aatccatata gtttaaataa tgagtgttaa
     4801 tattagcagt gaagaggtct ttttaagata ttcttctctg ctttttcata ttttttcgct
     4861 atgtagggta tgaagcaaaa tagaaagtag ttcgaatagt tgataaacag gaaactgctg
     4921 ttatttaaaa aaaacaataa agtaaagtat gttatcgtag aatacgatac aatagtaaaa
     4981 aagcaaaaag aatgcgtttt atatttgggt ttgaggttta taaaatagga taagcgtgct
     5041 gaaaacttag atatgacaaa caaaataaaa tttttaaaag ctacatagaa acatggtata
     5101 atgtatctaa aggaggtagc atatgtcctt agatatagat aaagaaaaga tgacaatcat
     5161 gggaatagct tttgaaaaca gatccgtttt taagagtgtt tggtatgctt taagtacaaa
     5221 tatgattgaa ggatggcgac ctacggttag tgatgttgaa aaattacgag atgaagctct
     5281 tgctctgggg atgacttaat gaagcgcaac tgttatgagt cttatgacta tgttgatccg
     5341 gataatttat ataccgatcc gggttcttca gttctaagaa ataagcagga aggaaaaaag
     5401 cacgcgagct tgaatatcgt atgattgcta gtaagagttt gaaattattt atcaatccta
     5461 tcttagttaa tagtttaaaa gtagtttgtt tcacaactgc ataagcttag aaaagttgaa
     5521 aagtgataac tctttaataa actcttggtt tgttaaaaga tattttgtcc actacatttt
     5581 ttcaattgac tattatttgt catagatata acagatagaa cagatagaac attgcattca
     5641 gaataatgaa aaacgcatca aaaatggtgc gttctgtttt tatgctacca taaaaggagg
     5701 aaaacaaatt gaaaattttt aagggagagt tttatcgaat ctctgtatta acagacaagc
     5761 tagtaaggtt agaatactct caaactggaa gttttgagga tagaacgaca caacttatct
     5821 ataatagaga ttttggccaa gtttcgttag attatatcga gacatcaaac gtactagata
     5881 ttatgacgga ctattttcat ctgcacttta ataaaggaga atttaacgcc gaaaatttat
     5941 ttatagaatt aaaaggaaat tttgccgtat atggtagtcg ctggtatttt ggtgaatcta
     6001 ttgaaacgtt aaaaggaaca gctcggactc tggataaggc agatggagca atctcgttag
     6061 aagatggaat tattagccga aatggtatag ccttattgga tgattctcaa ggatttattt
     6121 gggatgaaca atctggttat attgagagag aaaatcaaat tgacctgtat ttctttgcct
     6181 atgggcatga ttatagagga gcaatcagag acttttacca tttgactggt tcaacaccct
     6241 tgttgccaag atatgcttta ggcaattggt ggagtagata ttggccttat acgtcggatg
     6301 aatacttgga tttaatagac agatttgaaa cagagaaaat tccattatct atcggtgtgt
     6361 tagatatgga ttggcatata actgacattc cagctcgttt tggaagtggc tggacaggat
     6421 atagttggaa tagaaactta ataccaaatc cagaacagtt attgcaacaa cttcatgata
     6481 gaaagttaaa actctcctta aatgtccatc ctgctgatgg gatacgggct tatgaagaag
     6541 cttatcctca aatcgcaaaa cggttggggt taaatgtaga actagaagaa cctgctattt
     6601 ttgatttttt taatccctct tttagggaag cctactttaa agatgttcat tatgagctag
     6661 aaaagcaggg agtagatttt tggtggattg actggcaaca agggacacaa ggtatgctag
     6721 atccactttg gcttttaaac cattatcact atcaggatag ttgtaaaaat gcagaaggtg
     6781 gtttgatttt atcaagatat gcaggtcctg gtagtcaccg ctaccctgtt ggtttttcag
     6841 gggatactat tattagttgg aattccttaa ggtttcaacc ctattttaca gcgacagcat
     6901 ctaatatcgg ttatagttgg tggagtcatg atatcggtgg acatatgttg ggggattatg
     6961 acgaagagct acaaactaga tggctacagt ttggtgtttt tagtccgatt actcgattac
     7021 atagttctag aagtcctttt aatagtaaag aaccttggtt cttttcagaa acaacatcta
     7081 agattatgaa gaaatacctt cgtttgagac atcagatgat tccctatcta tataccatga
     7141 atgtaaagac acatgaggaa ggtgccccat taatcagtcc aatctattat ttctatccag
     7201 agaatgatga gagctataat gttccaaacc aatacttttt tggaacagaa ctgatggtgg
     7261 ctcccattgt agaaaagatg gatttgacat tccaatctgc aaaagtagat gtatggttcc
     7321 ctgaaggtga atggtatgac ttcttttcag agaaaaaata cacaggtggt gtgaagttaa
     7381 gtgtttatag ggacatctcg actacgcctg tgtttgcaaa aagtggtgca atcattccct
     7441 tggttggttc tgagataggt atgggtgttg atttacctga ggttgtagat tggtatgtat
     7501 tcccagggaa acaacatttt tttgaaatgc ttgaagatca aaatggtcaa agatataaaa
     7561 caagattatc aatcgattgg gaaatgggaa tggtagagtt agcattacaa ggagattcta
     7621 gtatcgttcc aagcaataga aaacatagaa ttcattttaa aggaacgaat gtgtctataa
     7681 ttgaattgcc aaataagaat gatacagcta aatttgaatg gaaagataat aaaaggacat
     7741 ctttaaatga cgaagttttt agactactaa agacagcttc tcttccatat gaattaaaag
     7801 atagattgtt aaatcaattc atcaatgcga aaaactctca tgacttaatg aatatcttgc
     7861 atcatcagga taaggaattg agagggcgtt tgttggaaat gatatttact agccaaaact
     7921 aattgaaata attagaaagt catttgttta gtgtatatga agattctgta tggtattcgt
     7981 tatcactggt cacattgaaa atgtgaaata agcacctaca acatagactt tacaacactt
     8041 catgtttcat atcatggggt gtttttctat ttaagtcaaa gcccatcaaa aaatctcact
     8101 attcatcagg ttaaaggaaa cctaatcata gtgagattgt gaattatagt agagtttgta
     8161 tcgcctcttc aatttgtttt gggtctgttt ttgaagaaaa gcgttcaaag acttgcccat
     8221 ctcgaccgat gagaaactta gcgaaattcc attcgattcg ttttcctagt gggccggatt
     8281 tctggtcttt taaccagaca tagagagggt ctgcttcctt accgttgacc ttaatcttgg
     8341 caaaacgtgg gaaggtggtt tgaaaatgta ggctacagaa ggcgttgatt tcctctgcgc
     8401 tgccgggtgc ttgtcccata aactgattgc aagggaaatc caatatttcg aagccctgat
     8461 cttgatagcg ttcatagagt tcttgaagtc cctggtactg gggcgttaaa ccacatccag
     8521 tagcagtgtt gacaatcaag agaactttgc cacgatagct atccaaggga gttgcttggt
     8581 tgttttggtt caaaacggaa aaatcataaa gtgaagtcat gagggcctct tttctttttc
     8641 tacattgtaa cagtttttac ttttttcgtc gagtcggatg gaagatattg ttgaagaata
     8701 agccttcaat atgatagaaa ccgtttacaa ataactttaa aaatggtatg atttaattaa
     8761 accggtttac ttagttgcta taaatctcta atttgagatt tagttcctat tgattttaca
     8821 atatgtttat tggagtgtat acatgcaaac aaaaacaaag aagctcattg tgagtttgtc
     8881 ttcacttgtt ttatcaggat ttttattaaa ccattatatg acagttggag cggaagaaac
     8941 gactacgaat accattcagc aaagccagaa ggaagttcag tatcagcaaa gggatacaaa
     9001 aaatttagtt gaaaatggtg attttggtca gacggaggac ggaagcagtc cgtggacagg
     9061 aagcaaagct caggggtggt cagcttgggt agaccagaag aatagtgcag atgcctcaac
     9121 tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga aattaagggc
     9181 agcggttcac cgtatggttc ctattgaagc taagaaaaag tataaactgc gtttcaagat
     9241 taaaacagat cataaagtcg ggattgccaa agttcgtatc attgaggaaa gtgataagga
     9301 caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga ccattgaagc
     9361 agactatagc ccgactttag atgttgataa aatcaagctg gagttattct atgaaacagg
     9421 aactgggact gtttccttta aggatattga gctggtagag gtagcagacc agccttctga
     9481 ggactatcaa acagataaac agcttgagga aaagattgat ttaccaattg gaaaaaaaca
     9541 tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg cttcagtcaa
     9601 aaatggaatt ttagaacctc ttaaggaagg gacaaccaat gtcattgtca gtaaagatgg
     9661 caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggatg catacacaga
     9721 ccgtttggat gactggaatg gcatcatcgc tgggaatcaa tactatgatt ctaaaaatga
     9781 acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc tatctagtat
     9841 ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata aaatgtctgc
     9901 aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga ccaatccttc
     9961 ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca tggaatggat
    10021 gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg attatgaaat
    10081 cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact tctctgatga
    10141 ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg aacatttccg
    10201 aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata tgggaagagt
    10261 aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta ccattcgctc
    10321 gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag atggatccta
    10381 tatcgaccat accaatgttg cctatacggg tgcttatggg aatgttttga ttgatggcct
    10441 gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag ataaaatgca
    10501 aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg gagagctgat
    10561 ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg tggccgcagt
    10621 agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa ccaaacaacg
    10681 tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg tctttaagaa
    10741 tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg caggagtcgc
    10801 aagtgttcca agaacaagtt acctatctgc ctttaacaag atggataaaa cagccatgta
    10861 caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta ccttgaatta
    10921 cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga tgttctatct
    10981 ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta atccatataa
    11041 gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag gtaaagtttt
    11101 accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag caaccatgga
    11161 tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc taaaggataa
    11221 gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg caactacaat
    11281 tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg ataaagaagc
    11341 ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt tagaatcatc
    11401 cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca gtatgagtaa
    11461 ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca aggaagttga
    11521 aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt atggctatat
    11581 gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaagagt tagaaagtag
    11641 cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag gagtttgggg
    11701 cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag ttttgaaacg
    11761 tggagtctat accattcgaa aagaagggga tgaatataag attgcctact ataatcctga
    11821 aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag cagctcagcc
    11881 acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc attcggatca
    11941 aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag ggttcttgct
    12001 acttggggcg ttttatttat tccgtagagg aaagaacaac taatttgttc atcatctaga
    12061 tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat atcttcggat
    12121 ttttctttta aaaaaggata agttgatact tatccttttt acttcattat gtgactatag
    12181 cgttttgaaa ctagaatagg acatcataac tgctaaaaga tttctataaa ttcatttgat
    12241 tttcctaatc aatttattcg tatcctattt cactctacta tattagtccg tctcgcacct
    12301 cacggagcga gacaaaacaa ccacccgcta tgcgggtgcg cgtcgaaggt tataccaaaa
    12361 aaactccaaa cgcgatacaa taaaggtgtt caatccactt gtaaagcgaa aggagaaaaa
    12421 atatggcaca aaaggctcat agtttatctc acacaaagtg gaggtgttct atcacattgt
    12481 gttcacccct aagtatagac gaaaagtcat ctataatcaa tatagaagta gtttaggcga
    12541 aatatttcat cgcttgtgta gttataaagg tgttgaaatg atcgagggtc acttaatgcc
    12601 agaccatgta cacatgttag tcagtattcc actaaggcta agtgtttcga gtttcatggg
    12661 ttatttaaaa ggaaaaagtg cactcatgat gtttgacaaa cacgccaatc tcaagtacaa
    12721 gtttgggaat cggcatttct gggtggaagg ttattatgta agtccagtag ggcttaatga
    12781 agccacaatt aagaaatata gtcaagatta aagaaattat ccagtggatg atttcttcac
    12841 gagtatgaaa atttgagaac tagtaaagta tgatatatag taaaatgaaa taagaacagg
    12901 acaaaatcga tcaggacagt caaatcgatt tttaacaatg ttttagaagt agaggtatac
    12961 tattccagtt tcaatctact atagcactag ataaattgag tgtaaaagaa tatgaggatc
    13021 cctttaggga tagtggtaag taataccaaa gtctcttaaa gaggcaagtg acgagtcaag
    13081 agcaataagg cttgaacaac gtaaaagcca gcgtctttag gcgctggctg atgatttggg
    13141 cttatagctc tgggataaac cacccgttag acgggtagtt atgattttat ctgagtgtaa
    13201 tatactgttg ggcaatctcg ctgatgcggt caaagttgcc ttgggaagcg agtttattga
    13261 gttcgccacc aattccaacg gcatctgcac cagcagcgaa ccattgaggg atgttgttta
    13321 ggccgactcc tccggttacc attacggaaa cttgtgggat cggtgccttg actgcagaga
    13381 tatatgctgg actgagagta ctacctggga agagtttgat gatttcacta ccggcttcaa
    13441 gtgcagtcgt gatctctgtg agggtaatac agcctggaat gtacggtgtg ctgtagagat
    13501 tgcacatttt cgcagtttca gcatggaaag atggagaaac aacgtaattt gctccagcta
    13561 gaatggcatc tctagcagtt acggcatcaa gcacagtacc tgcaccgata caaacactct
    13621 gatcgtcctg atacaagtct acaagttcct tgatgatttg tcctgcatac tgattggtat
    13681 aggcgatttc aatagctttg ataccgccct tgatacaagc aatcgaggct tgtagtcctt
    13741 cttcctttgt atttcctcga atgacagcga caattttctg tttttttagt tcaataatcg
    13801 tatctgattt ggtcatgtaa ttctcctaac gaatgatatc ttgtgcattt gccagtaaat
    13861 tttcaatact agttgcggaa gtggagagat ggtctcctgg aagagtgcat ttgagagttg
    13921 cgctcgcaac tgcaaagtca atggtagttt ttagggagga atgatggagt agttggtaaa
    13981 gggcaccaga tataaaggca tccccgctac caattcgttg atagactgca gtttttagtt
    14041 ggacagactc ttcaaatcgt tcttccagag cataggcttg atagacattt ttgtcttgct
    14101 catcactaga tcggagggta tggaaaatgg ccttgaaacc ataggcttct tttaaaagtc
    14161 gcatgcgatt ttccacctct tctaggctag cactgtctct tggaaacatc tctagatttt
    14221 ggtcatcaat catgagagga tcaataccga agcaatagtc agtaaaacgt gcaaacttag
    14281 aaaattcata cttggcttct aggactgaaa tcatctttgt tctcagattg agatccattg
    14341 aaacgacaat tcctcggcgc ttggcttctt ccaagagtag gagaaggatc gcacggacct
    14401 cttgaccgat agctatggtg attccactaa aatgaaaatg gctaatcccc tgaaagagag
    14461 aatccatatc tagcatgttt ggccgaatct ggctgatact cgtatgctta cgatcgtaga
    14521 aaacttcact ttgacgacaa ccaaagccgt tctccaaata gtagaggccg attcgatcgc
    14581 caagccgaca gattgaactg gtatcgattt ggtgctgttt caagaatgtg agaaaacgat
    14641 ctccaatctc gttggcaggg agtgcggtaa agactttcgt tgagataccc agggcttgca
    14701 aattacaagc gatgttaatt tctgatccgc caaaataagt cgaactggca acatgatcgc
    14761 cgatactggt ggcatctaat ggtgagattc gaattaatgg ttcgccaaac agtaatattt
    14821 tcgtcatcca ttagttcctt tctggtttag aatagcttta cttggctaat acttctttca
    14881 aataagcagc gacttcatca tcttggcagt tttcaaagaa gtattcttgg aagtatttgc
    14941 cagagatggt gtctttgagg aagtcttggt cgattgtttt aaggatggtc atcaaatcat
    15001 tgtgggtgat ttgtttcacc tcgtttaaga tacgagcgtt gcgttgttca gggattacac
    15061 gttctcttgg gtagccaccg cccatttctt cagcaaataa gcgttcaaac atcaatttga
    15121 gggtcagttc tgccccccag ccaaatcctt tggcataagg gatagacaag gcgttaccac
    15181 cattgatttg agaataaagg taagcgtcag ttgggtccac tgctagacca cagacaacac
    15241 cagggaagct gtttaaagca agcatagccc ctacacccgt accacagccg gtaacaacaa
    15301 agtcaactgc ctttgtattt aaaaggatgg cagccattag tccgttctgc acataagtta
    15361 attgactttc tccttcttct ccacgcatac catagttaaa taattggtag tcttttttat
    15421 ctgtcgcttc ttttagacta tcgtaaataa tgtgattctt gctagcttga ctattttcat
    15481 tgattaatgc gattttcata agatcttctt tctattttta ctcaggttgt tttccgatgt
    15541 aggctaagat accgccatct acatatagga tgtggccatt gacaaaattg ctggcatcac
    15601 tagcgagaaa gacagcaggg cccatcaaat cttcaggatt tccccaacgt gcagcaggtg
    15661 tttttgcaat gatgaactgg tcaaatgggt ggcgagaacc atcttcttgc aactcacgaa
    15721 gaggtgctgt ttgaggagtg gcaatataac ccggtccaat tccgttacat tggatattgg
    15781 ctccaccgta ttcagacgca atgttgcggg tcaacatttt caagccccct ttagcagcag
    15841 cataagcgct aactgtttca cgtcccagtt cgctcatcat cgaacaaata ttgataatct
    15901 ttccatgccc tttctttatc atagaaggaa taactgcctt tgaaacgata aatggtgcgt
    15961 ttaagtcaat atcgatgacc ttacggaaat cagcggcgct catttcgcac attggaactc
    16021 ggcggataat accagcgtta ttaacgagga tgtcaatgac accaacctct tgttcgattt
    16081 gcttgaccat ggcttggata ccgtcctcgt ctgtcacgtc acagacatat ccatgggctt
    16141 cgatgccaac ttcacgataa gcttcaatcc ctttattgac cagatcttga ttgatatcgt
    16201 taaagacaat agtagcgccg gcttcagcgt aggatttggc aatagcaaat ccaattccat
    16261 aagaagcgcc ggtgatgaga gcaatttttc cttttaaaga aaactgctca attgagaatg
    16321 atgtatttgt catttgatac ttcctttcaa atttgttaag acttctctat aac
//
LOCUS       DBERDS010000043        16244 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.043, whole genome shotgun sequence.
ACCESSION   DBERDS010000043 DBERDS010000000
VERSION     DBERDS010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16244
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.043"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..903
                     /locus_tag="ACL73E_001604"
     CDS             <1..903
                     /locus_tag="ACL73E_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGS0801546.1"
                     /translation="IGDESYSFSTLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWS
                     FGLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSS
                     LILFLLAKKDGFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFA
                     KLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLT
                     AFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPV
                     GVVTGLLGSPYLIYLLIKMNRRNI"
     gene            903..1697
                     /locus_tag="ACL73E_001605"
     CDS             903..1697
                     /locus_tag="ACL73E_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801547.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            1848..2032
                     /locus_tag="ACL73E_001606"
                     /pseudo
     CDS             1848..2032
                     /locus_tag="ACL73E_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            2085..2510
                     /locus_tag="ACL73E_001607"
     CDS             2085..2510
                     /locus_tag="ACL73E_001607"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0801548.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            2566..2883
                     /locus_tag="ACL73E_001608"
     CDS             2566..2883
                     /locus_tag="ACL73E_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGS0801549.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            3193..4833
                     /gene="mobQ"
                     /locus_tag="ACL73E_001609"
     CDS             3193..4833
                     /gene="mobQ"
                     /locus_tag="ACL73E_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HGS0801550.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKAKTIHKEMEDVEK
                     KILYYEIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDIDQYKVVSGKLKKLLSDKEKLS
                     PKKWNEEKILLMSNLEEINKEKDKIKDEYQEINHIKYSVDFVNKELGIDLSIEIDKLI
                     KQGEKPSVIAQIKKFQDQVNKDNEYREMMKNKKMDQER"
     gene            4907..5080
                     /locus_tag="ACL73E_001610"
     CDS             4907..5080
                     /locus_tag="ACL73E_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801551.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            5266..5793
                     /locus_tag="ACL73E_001611"
     CDS             5266..5793
                     /locus_tag="ACL73E_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGS0801552.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            5920..6648
                     /locus_tag="ACL73E_001612"
     CDS             5920..6648
                     /locus_tag="ACL73E_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGS0801553.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            7332..7493
                     /locus_tag="ACL73E_001613"
     CDS             7332..7493
                     /locus_tag="ACL73E_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801554.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            7585..9264
                     /locus_tag="ACL73E_001614"
     CDS             7585..9264
                     /locus_tag="ACL73E_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGS0801555.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGYKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            9532..10098
                     /locus_tag="ACL73E_001615"
     CDS             9532..10098
                     /locus_tag="ACL73E_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801556.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            10419..10607
                     /locus_tag="ACL73E_001616"
     CDS             10419..10607
                     /locus_tag="ACL73E_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGS0801557.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            10669..11427
                     /locus_tag="ACL73E_001617"
     CDS             10669..11427
                     /locus_tag="ACL73E_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGS0801558.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            11485..12339
                     /locus_tag="ACL73E_001618"
     CDS             11485..12339
                     /locus_tag="ACL73E_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGS0801559.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            12451..13335
                     /locus_tag="ACL73E_001619"
     CDS             12451..13335
                     /locus_tag="ACL73E_001619"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGS0801560.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            13498..14577
                     /locus_tag="ACL73E_001620"
                     /pseudo
     CDS             13498..14577
                     /locus_tag="ACL73E_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            14571..15907
                     /locus_tag="ACL73E_001621"
                     /pseudo
     CDS             14571..15907
                     /locus_tag="ACL73E_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(15948..>16244)
                     /locus_tag="ACL73E_001622"
     CDS             complement(15948..>16244)
                     /locus_tag="ACL73E_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HGS0801561.1"
                     /translation="NKRIVTQLAINCFILSIDKEEFSNCSYLINEIKGLLENELNFYE
                     QTVFLYATGYYEFKRQLSSGIETMKQAIQVLDILGEDKLKLHYTSHFDKLVNNK"
BASE COUNT         6457 a         2202 c         3043 g         4542 t
ORIGIN      
        1 atcggagatg aaagttattc tttttcaact ttgattaaag tcttaaatag tgaaactgtt
       61 cctggagcta gtttttcgat tatggaaatt agattaccaa aattattagc aggaattata
      121 gctggctggt cttttggatt ggcaggattt atctttcaaa ctatgttaag aaatcctctt
      181 gcaagtcctg atataatcgg tgtcacaagt tcttcatcta ttgcagcggt cttttgcata
      241 ttggtattaa aaacaaatag tttaactact ggaattattt caataacttg tggactaaca
      301 tcatctttaa tattattttt actagctaaa aaagatggtt tttcagcagc aagactgata
      361 atattaggta ttggttttca agctgtcaca agagcaggca cctcattttt attgttgaaa
      421 gtagcaagat atgaattaca agaagttatg agatggctca gtggctcttt atcttttgca
      481 aagttagatg acatacctct tgttctaata gtaagtatta ttgctactat attagtttta
      541 ttttttaata aaagactaga aattattgaa cttggtgaag aaatagcaat cggacttgga
      601 gcaaatcccg agctttcaag gcttgtttta attttttgcg ctgtatcttt aactgctttt
      661 tctacttcaa ttacaggacc aatagcttgt atatcttttt tagctggtcc catagcctta
      721 aatattggca agaaaagaag cccaatatta gctggattgg ttggaatttt actagttttg
      781 ttatcagaca tattctctca aaatatttta ccagctagat atccagtagg tgttgtaact
      841 ggcttgttag gttcaccata cttaatatac ttactaataa aaatgaacag gaggaatata
      901 taatgaaagg tctgtggtca aataatctta cctgcggtta tgatgaaaaa ataatcttgg
      961 aaaatataaa tataaaaata cctgaagaaa aaatatcagt tattattggg tcaaatggtt
     1021 gtgggaaatc aacactcatt aaaaccttgt ctcgacttat aaagccatta gagggagaag
     1081 tattgcttga taataaatca attaattctt ataaagaaaa agatttagca aaacacatag
     1141 ctatattacc tcaatctcca ataatccctg aatcaataac agtagctgat cttgtaagcc
     1201 gtggtcgttt cccctacaga aagcctttta agagtcttgg aaaagatgac cttgaaataa
     1261 taaacagatc aatggttaag gccaatgttg aagatctagc aaataaccta gttgaagaac
     1321 tttctggggg tcaaaggcaa agagtatgga tagctctagc cctagcccaa gatacaagta
     1381 tcctactttt agatgagcca actacttact tggatatctc atatcaaata gaactattag
     1441 acctcttgac tgatctaaac caaaaatata agacaaccat ttgcatgatt ttgcacgata
     1501 taaatctaac agcaagatac gctgattacc tatttgcaat taaagaaggt aaacttgttg
     1561 cagagggaaa gcctgaagat atactaaatg ataaactagt taaagatatc tttaatcttg
     1621 aagcaaaaat tatacgtgac cctatttcca attcgcctct aatgattcct attggcaagc
     1681 accatgttag ctcttaataa ttgaatatcg gaattcattt aaaagtcgca aattttgaac
     1741 tgaccctcaa aagttaggcc aaaaaactaa ctaaaggagg tcagtttttt aatggcaaat
     1801 acagcacaga atttaagata aaattagtaa aagaatatca tgaatgaaaa ataggatata
     1861 gataataaca gcaatattaa aaagatcagg actgataata aacaaaaaga aagtacaacg
     1921 actagttcaa aagctaaaac ttcaagtaaa aagttattca agaaaatcta gaaaatactc
     1981 atcctacaaa ggacaggtag gaaaaatatc agacaacaaa ataaaaagaa atatttatta
     2041 ccgaaaaaaa ggggaaatcg agtcaagtac caacaggctc atctattcca aaaagatatt
     2101 tactcgatgg aaaaactcct agaattagtg ctacaaatat tgacaatggt atcttaggtt
     2161 actacgaaga tatagatgat aaaaattata gagtttttga aaattttata tctgtttcat
     2221 ttttaggagc agtcttttat cataaatata aagcaagcct agatatgaaa attcattgtt
     2281 taaaattaaa aaataaagaa ttgaataaag aagtagcatt ctatttaact tcaattatta
     2341 ggcaagcttt aaaaaatact gaatataaag atcaaatatc tagcacagta ttgccagata
     2401 tcaaaattaa attaccgata gacagtagag gtactccaga ttggaattac atggaaagat
     2461 atatagaaga cttaaaatta aaatgcaata tagcaaatta taatatttaa aacaagaacg
     2521 attagaaata aaaatctagt cgttttttat ttttagaaag gatacatgat ggcaagtaaa
     2581 agattaagta ttgaagaaca gattgaaaag aaagaagaaa gcattaagca attacaaaat
     2641 caaaaaagac agttgaagaa aaaacttaat gaacaagaaa gaaaagcaag aaacaaaaga
     2701 cttatagaaa aaggtgcagt gtttgaaagt atttttgaag aaagtattga tttaacaaaa
     2761 gatgaatttt ataagttaat aaaaacgtta aatgatgaag aaataagatt aaacataatg
     2821 gaaattttag aagaaagaat agatgataat gtagaaaaat catctaaaga tgaaataaca
     2881 taattgtccc ttggttacaa gggcgcaatt atacacccta aagggtgctt gcgtcctgcg
     2941 gagtcaaacc cttgcaggga gtaacaacca ttcgcttttt aaaagtcaag ggtaaataaa
     3001 ctcgctaagg ctcgcccttg acttttaaaa tttgaaatga aagtaacaat taagccgaca
     3061 tactgaaaca acaaaaatta attcagtagt cggctttttt aattctatca tttcaaaacg
     3121 ctcattcaca aagaggatat aaaaaaacta ttaagcctcc acctaaaaca acaaagaaag
     3181 gaagtgataa aaatggcaga cagttttcat ttttcagtaa acataatatc aagaggaaaa
     3241 ggcaaaagtg cagtagcaag tgcagcatat ataagtggag aaaaaataaa aaatgaatgg
     3301 gacggagtaa cccatgacta tacaagaaaa gaaaaaatat tagtaaaaaa tataatattg
     3361 cctgatcata taccaaaaga atttaatgat aggtctacct tatggaataa agtagaaatg
     3421 gcagaaaaaa attctaatgc acaactagca agacaattca taataggact accaaaagag
     3481 ttatctttaa gtgaaaataa aaacctggtt gaaagatata taaaagaaaa tttaacatca
     3541 caaggaatga tagtagatta tgcaattcat gatgagagtc aagataaaaa tggaaatatc
     3601 cattgtcata taatgaccat aatgcgacca ataaacgaaa aaggagagtt cttagccaag
     3661 tcaaaaaaag aatatatcct agatgaaaaa ggagaaaaag tattaaacaa aaatggaaaa
     3721 ccaaagacaa gaaaagtaga actaacaacc tggaacgata caggcaatgt agaaaaatgg
     3781 agagaaaatt tttcagatct ttgtaacaaa tatttagaaa gagcaggagc agaaaaaaga
     3841 gtagaccata ggagttttaa aagacaaaat tcagattatc taccgacaat ccatttagga
     3901 tcagcagcaa gtgcaatgga aagaaaggga atagaaactg acaagggaaa ctataataga
     3961 gaaataagaa aatataatca acttgtaaaa acaataaaag aagagataaa aacattaaag
     4021 ggttggatag gaaatttatt agataactta tctactgctt atgaaaaatt taaggatata
     4081 gaaagagata aggtaataga caaccctaaa ctttttaatc taacaaatta tctattaact
     4141 tattcagaaa ttcaaaaaga aaaaagtaaa tatctaaaag gatatgcaaa aactaataaa
     4201 gaaaaatatg acttcaaaaa gctaacaagt gcatatagtt atttaagaaa aaacaacata
     4261 gaaaccatag gtcagttaca aacaaaaata gaaactttaa agtctaatag ttataggcta
     4321 aataaaaaag caaagacaat ccataaagaa atggaagatg tagaaaagaa aattctatac
     4381 tatgaaatct acaaagccaa aaaagaagtt tatgaagaat atcaaaagaa aaatatattc
     4441 acaaaagaag cattttataa caaacataag aaagatatag accaatataa agtagtaagt
     4501 gggaaattaa aaaaactcct atcagataag gaaaaactaa gtcctaaaaa gtggaatgaa
     4561 gaaaaaattc ttttaatgtc aaatcttgaa gaaataaata aagaaaaaga caagataaaa
     4621 gatgaatacc aggaaattaa tcatataaaa tattcagtag attttgtaaa caaagaactt
     4681 ggtatagatt tatccataga aatagataag ctaataaaac agggagaaaa accaagtgta
     4741 atagcacaga ttaaaaagtt ccaagaccaa gtcaataaag ataatgaata cagagaaatg
     4801 atgaaaaaca agaaaatgga tcaagaaaga taagacctgg taaaaatatc ttatccaagc
     4861 tataatatga ccaaacaact aaagtcagat ctaggaggta atagagatga ataaaaggca
     4921 agagctaata gatgaactca taaaagcaaa tgaagatgga acatacaaaa cctataaaag
     4981 cacagaagaa ataaaagcaa tgaacaatga agaaatacag attatatatt ctaacatgaa
     5041 aaactatcta tcagacaaaa gaacacacat aaactattaa aggtggaaag gtagtgtaag
     5101 ctatttttaa aagtataaaa ggtacaaaga cctaagaaat atataaaaac atcaaaataa
     5161 agtattccac caccaagaac aataaaataa aaacaagcaa agggaagtat agaaaaatta
     5221 aaacctatac ttcccttttt taattcaaac aaaggagaga aaagcatgat aaacgaagaa
     5281 ataagcaagg aagcaggtca agcagcacaa accataatat catacacaat aaaggcaaca
     5341 aaagaatcaa tcaatttaga aaaagaaata agaaaaaaga tgaatgaaac tttagaaaaa
     5401 gcaaatggaa acttaaaaag tcttatgggc gatgaaatga aaataaaaga cctctacaag
     5461 aaaggacaac tagaaaatat aagcatagat caaatcgacc tcaaagactt aaaaaaagaa
     5521 ctaaacaaac ttggagtaag tttctcagta atgaaaaaca aagaaagcaa aaactatgaa
     5581 atattcttcc aagccaaaga cataaaagta atggaatatg cctttaagca agtcatagcc
     5641 aaggaaaata aaaaagaaaa agaaagtatc ctaaaacaaa taaagaaata caaagaccta
     5701 tccaaaaaca aagataagac aaaagaaaaa ggaaaaagga aagtaaaaga aaaagtaaaa
     5761 ccaaacaaaa aagatatgac cagagaaatc taaagggagt aacgaaaagt tacaccctta
     5821 aataaccata ataacaagac ttccgaaaaa cagaagtcca gaattccgaa aatcggaaat
     5881 caagaatttc gattatcgaa aatcaagaaa ggagcagata tggcaacaaa caaaagatac
     5941 tattggataa aattaaaaga agaatttttc acagacaaaa ggataaaaag gttaaggaga
     6001 atatctggag gagataccta tacgataatc tacctaaaac ttctactact aagcctaaaa
     6061 gatgagggca aactctatta tgacggagta gaaagtgatt ttataaaaga gttagcacta
     6121 accatagatg aaacagacga tgatgtaatg gtaacagtaa attatttaat caatcaaggc
     6181 ttattagaag ttgtaacaga aaatgatgaa tactacctaa ctgaaatacc aaacttaatc
     6241 ggatcagaaa cagcctgggc agagaaaaaa agaagataca gacaaaataa acagaggaca
     6301 ttgtccttaa tgagtccaac ccatgtccga caagagatag agatagagaa agatatagag
     6361 atagataaag agagagaggg agagatagat aaaaagtcca cccccatttt ttatggagaa
     6421 ttcaaaaatg taaggttaag caaagaagaa tataaaaatc taaaagaaaa attaaactca
     6481 cacacagata taatgataaa taaactatcc agatacatgg aaagcagtgg taagacctat
     6541 caaaaccact atgtgacaat cttaaaatgg tatgaagaag ataaagacaa actaagacag
     6601 aaaggtttaa ataaaaaaat gaattatgat gtaggagaat ctttatagat aaaaagaggt
     6661 ggaaaggcac tattaaagac tttaagttta aaaaggtatc aaagtatgcc agagataaaa
     6721 aaatataaat atgacacttt aaaggcgatt agaaaattaa agaaatgcta gaagactttt
     6781 agatgacagt taccaagagg gtctaatttt cactgctact tatgcagtag gaattggacc
     6841 tttttatata agcaaattct atttcaaaat tggttaccaa gaaagacttc ttttcactgt
     6901 taagtataag agggtaattt atagaatttt gttacatcaa gataaatatt ttctgatggt
     6961 caaattttaa aaagattaat aactctcgat aaattttgaa ccttaacaat tgaatagacc
     7021 aagacaagac gttaattatt tttggagcgt aataacctat ccgtcaagat ctttcggctg
     7081 aataattcgg caaaaaaagt tctgctaagc aaaaagaaag tgagcgataa gtaagagttt
     7141 gaatataggg agggataccc tatccgctat gaagaaaatg aggataatga tacttctaag
     7201 gttgaagcag gctcatccgg aatagaggcg gaggtgagat tcctatgttg ctaatccaaa
     7261 gcacttgtca atgtcaaaaa acttaattaa acaaataatt attagatata aaactttaga
     7321 ggaggtatat attggacaat gactggaatg gattggctga tttaatagca aatctgattg
     7381 caaaatatgc tggtgcttta gatttagata atctacccga tccaacgcca gcaaaaaatc
     7441 aagagatgaa aaatagtttt gacatggcaa aaacacaaat tgagacggac taataaaagt
     7501 gttataatat acttgaaatg atagtccaaa cttaaattaa aaaaattata tatgatatag
     7561 aaaaattata ttgaggttaa tactatgtca aaagaaaaaa taaaagtata cctctataca
     7621 cgagtatcta cgtcaataca gatagagggg tattcgttag aggcacaaaa atcacgaatg
     7681 aaagcttttg ctatttacaa tgattatgaa attgttggag aatatgaaga tgccgggaag
     7741 tctggcaagt ctattgaagg tagaatacag ttcaatcgaa tgatggaaga tataaaatct
     7801 ggaaaagatg gagtatcttt tgttcttgtg tttaagttat caagatttgc aagaaatgcc
     7861 gctgatgttc tttctacact tcagataatg caggattatg gagttaatct tatctgcgtt
     7921 gaagatggca ttgattcatc taaagatgct gggaaactaa tgatttctgt tttatcagct
     7981 gtggctgaaa tagaaagaga aaacatccgt attcaaacaa tggaaggtcg cattcaaaaa
     8041 gcaagggaag gaaaatggaa tggtggcttt gctccgtatg gatataaact tgaagacggc
     8101 aagctgttta taaatgagga agaggcagtt gcaataagaa cgattttcga ccagtatgta
     8161 aatactacga taggagccaa tgggatatct aaatacttag agaatcatgg aattagaaaa
     8221 atcccaagac agaatggtaa gaatcctttg tttgatgcag gtcttataag aaagatatta
     8281 aagaatcctg tatataatgg gaaaatagca tttggaagaa gaactttaga aaaagttcat
     8341 ggtacaagaa atgaatataa gcaggttgaa caagatgaat atctaatatc tgaagggata
     8401 catgaagcta tagtttccga tgaagtttgg caagctgctc aggttaagct aaaatctcaa
     8461 gcaaagaaat atgagcatgt gaataaagga aaagatacac gcacacactt gctttctgga
     8521 attgtaaaat gcccgatatg tggagtggga atgtttggga acaagtgtat caagaaaaag
     8581 aaagatggca caaagtataa agatttttat tactatggtt ataaacatag gcagatgata
     8641 agaggtcata agtgtacatt cagtaagcaa attagagaag aattgttaga tgatgctgtt
     8701 gcagaggtga ttgtcaagat agtaagtaat ccgaaatttg cttctatgat gcaagaaaaa
     8761 atcaacatga aggtggatac ctctgaaata gaaaaagaaa tagataatta ccaaaaggaa
     8821 ttgagaaaga gtcattctac aaagtttaag ctaattgagg aaatagataa tttagatgtt
     8881 gaagataagc attataagag aaggaaacag gatttagatg atagactata tcgtatgtat
     8941 gacaaaatag atgaattaga atcatcacta attgatgcga aagcaaagaa acagactatt
     9001 gaagctgaaa agcttacagg agataacata tataaggttc tgatctattt tgataagctc
     9061 tataaagtca tgaatgatgt agagcgtagg cagttaattt cagctttgat ttctgaaatt
     9121 caagtttatg aagaaaaaca atctaacgga caatggctaa aatccattac ttttaagcta
     9181 ccaattatag aagaaaatct caacataggt ttggataatg atgaacaagt tgaatgtgta
     9241 agtttattag agaaacgtag ttaatcctca aaaggttccc caaacctttt gagtcccact
     9301 gacgcatcac gctgaggcgg tatcactgct tgtacgagtt gaagcatcag cgaagtaaaa
     9361 gtagatgttc agccaatgcg acgaggtgag accgaaggtc gataaggtgt gttctgggta
     9421 taggactcgt aaagtaagta ggaaatatga tgagatgata cagagagcat gaattggtca
     9481 ggtgacgtgc ttatttacat tagcctgata atgaaaatgg agagattatc gatggttata
     9541 ttggaattgt accaaaatga ttattctaaa gatttagtag catttgattc catagaagat
     9601 gggaaagcct ttgtagctca aatcccggga tacactctgg aaacagaaga tggttttgaa
     9661 gtggagtatt ttaatcctaa aaacataccg gattatatgg aaattatttt taacggaaat
     9721 attgttcctt tatctaaatt tatgttcgat cctgaggaaa atgtaaacat tatttggaaa
     9781 gagatttcaa atttatccct caaaaatgat agagtgatcg aaggatattc aaaaattgat
     9841 gcatatgtcg ttaacaacca tgaagttaaa gcctatgtcg aaacaagaga aacgaactat
     9901 cgtaaagcaa aagacttctt agaaagccgc ggatatgaaa tcgacagaag ctttttcgga
     9961 agtgaagacg gtgaagcgat tctttacaga aaaaaaggga tcgaagtttg gcatttcttg
    10021 tgtcacttag acccaatgtt tgtagagatt gaagatgtag aaggatatgt taaagaagaa
    10081 gttggagaga ttcaatagtc aaccaaagtt ccttgtgagt atataccttt gctagtaaaa
    10141 gagtcaaaac gttataacga aggggggaag aaaacccttg agtgtaagtc tttttcttgt
    10201 ttagagggaa agtattagag tagccgctca taatttatac tagatttgat aactgatttg
    10261 agacagattt tatttctata aatattgtga aaatttttta ataccaaaga tttaaagtta
    10321 ctgtgttaaa aatcctctcc acttttaaac taatgtatta taaaagccag ttgacacaag
    10381 tgttacacct atgatagaat taacttgagg tgatgaaaat ggcaaccgat aaaaatagaa
    10441 taatgattag cttggatgat aaaaatctag agaaacttga aaatttagta gaagatgcta
    10501 gagatagaag gggaatgcga ctaacaaagt cccaggttat tgaattactc ctaaataccg
    10561 ttgattattt cgatgatatt atgggggcta tttactcaaa aaaataagag caaaattgct
    10621 attatttttt acaaattggt gtaacactag tgatatagga gtgatgaaat ggttgtttat
    10681 attagacaaa gtaaattacc aagtgaggtt tcaattaata aatacaatgc tcaagtaggt
    10741 gcctacttac aaggagaaga agttatttta tatcaatctt tttctgaaat aaaagagtta
    10801 acaagtgaag atatagttgt agattatata atggagacta gagcattact aaaaatgatg
    10861 ggcttaaacg ttccggttca tgactatcct attgagctta aagagtttta tggtcgaaag
    10921 atttatgctg gtattttagg agagattgtg aatatacctg ataattgggg aaaatttatt
    10981 aagcctaaag ctggttcaaa agtctttact ggaagagttg ttaatggaac ccatgattta
    11041 ataggtattg gtctaccttt cgactatcct atatggatta gtgaggttgt agaattcata
    11101 gctgaatggc gttgttttgt gttagatggt cgcgtattag atgttcgacc ctatacaggt
    11161 gattatcatg cacaatttga tgcaagtgta attgatgaag cgatatcatg ttggaaagat
    11221 gcgccaatag cttatggact agatatcggt gttactcgcg atggcagaac acttgttgtt
    11281 gaagtaaatg atggttatgc attgggaaat tatggcctat ctcctttaaa atcaatcaat
    11341 tttcatagag ctaggtggaa agaaatggta aaaccctatt ttgaaaaaaa tgaaattttt
    11401 aaaatccaac aggatgttat tttctaaaat aaatatggta gataaccaat ataaaaagca
    11461 tcaaaatgaa caaggaggaa tctgatgctt ggagcaatta ttggagatat tgtcggttct
    11521 gtttacgaat ggaacaatat caaaacaaag gactttcctt tatttcggaa ggactgcttt
    11581 tttacagatg acacggttat gacctgtgct gttgcagaag caattatgaa tggtggacaa
    11641 aaagacgact tcattgacgc gatgaagaaa tatggcagaa tgtatccgaa tgctgattac
    11701 ggtgctcggt ttaatgcatg gctaaacagc gataaccgtg agccttataa tagctttggg
    11761 aatggatcag ctatgcgtat ttctccatgt gcttggatca tggactgtgg tttttatgcg
    11821 aaaactggta tatggccatc atctagagga cttacgagtc tttctgcaga ggtaactcat
    11881 aatcatccag aaggtgtcaa aggcgctatg gctacagctg atgctatctt tctatgtcgt
    11941 ttttactttg gtggttattg tagagagtac gagcaatcaa ttaacgacaa tcctacagag
    12001 tgtaaaagac gaattaagga ttatatagaa aaagaatacg attacaatct atctcaaact
    12061 ttagatgaaa tccgtcctaa ctatcgtttt aacgaaacat gtcaggaaac tgtccctcaa
    12121 gccattatcg cctttcttga aagtagagac ttcgaagatg cgataagaaa tgccatctca
    12181 cttggtggcg acagtgatac tctcgcagca atcacttgta gcatagcaga ggcagcttac
    12241 ggtattcctg attggatcaa ggataaggcc tattcttact tggatgaacc cttaaaggat
    12301 gtagttaggc gatgggaaaa tagaataaaa gcgtattaat ctccagtacg tcagatttct
    12361 cttttctgta ttttcattgt ataataggat tacatttact tgcatacgac gaaatgtaaa
    12421 catttctgtt taaaattaag gataaaatca atgaaaaaag caatggtaat tatcaaccct
    12481 acttctggtg gcgagaaggc tttggattac aaagaaaagc tggagaataa agcaaaagaa
    12541 tactttgaat atgttgaaac caaaattacc gaaaaagcgc tggatgcaac acattttgct
    12601 gaagaagctt ctcgtgagca gtatgatgca gtggttgtgt ttggtggaga tggaactgtc
    12661 aatgaagtca tttcaggtat tgatgagaga gactacattc ctaagttagg gattatccca
    12721 ggcggtacgg gtaacctcat tacaaaactt ttggaaatca atcaagacat cgatggcgca
    12781 attgacgaac tggattttga tttaaccaat aagattgata tcggtaaagc aaatgacaac
    12841 tattttggtt atatctttag tatcggttct ctgcctgagg cgattcacaa tgttgaaata
    12901 gaggacaaaa caaaattcgg tattttaacc tatgctgtaa ataccatgaa gtctgtcatg
    12961 acagatcagg tctttaacat taaggttgag acagaaaatg gaaattatgt tggtgaagct
    13021 agccatgttt tggtcctttt gacaaattac ttcgctgata agaaaatctt tgaagaaaac
    13081 aaggacggct atgccaacat tttgattctg aaagatgcct ctatattctc caaattatcc
    13141 gtcattcctg atttattaaa aggggatgtt gtcgcaaatg ataatatcga gtatatcaaa
    13201 gcgcgtaata ttaaaatctc ttcagatagt gaattggagt cagatgttga cggagataaa
    13261 tcagataacc tacctgtaga aatcaaagtc ctagctcagc gagtagaagt attttcaaaa
    13321 ccgaaagagg attagtatat agagaaagcc ttttttaagg ctttttgtat actttaaaag
    13381 atagttcctt taacaacgga cattccttgc aaatagttta caaaaatagt atactggatt
    13441 tattgagttt gaaaacgttt gcgtaaaatt tgaatgaata ctttaggaga caaattgatg
    13501 gaattgagtg ctatttacca taggcctgag tcggagtatg cctatcttta taaggataag
    13561 aaactccata ttcgaattcg aactaagaaa ggggacattg aaagcatcaa cttgcactat
    13621 ggggaccctt ttatctttat ggaggagttt tatcaggata caaaagaaat ggtcaagata
    13681 acttctggta ccttatttga ccattggcag gttgaagtgt cagttgactt tgcacgtatc
    13741 cagtatctct ttgagctcag agatacagaa ggtcaaaata ttttgtatgg cgataaaggg
    13801 tgtgtggaaa attctctaga aaatcttcat gcaattggga atggatttaa gttgccttat
    13861 cttcatgaga ttgatgcctg caaggttgac tgggtttcaa atacggtatg gtatcagata
    13921 tttcctgaaa gatttgccaa tggcaatgct ctattaaacc cagaagggac tttagactgg
    13981 gattcatctg tcacacctaa gagcgatgat ttctttggtg gtgatttaca ggggattatt
    14041 gatcatatgg attacttgca agacttgggt attactggac tatatctttg tcccatcttt
    14101 gaatctacaa gcaatcacaa gtacaatacg acagattact ttgaaattga ccgtcatttt
    14161 ggagacaagg agacctttcg ggaactggtg gatcaagcgc atcatcgtgg catgaaagtc
    14221 atgctggatg cggtatttaa tcatattggt tcgcaatctc ttcaatggaa aaatgtcgtc
    14281 aaaaatggtg aacagtctgc ttataaggat tggttccata ttcaacaatt cccagtgaca
    14341 actgaaaagc tagttaataa gagagactta ccctatcatg tttttggttt cgaggactat
    14401 atgcctaagc taaatacagc caatccagag gtcaagaatt atcttttaaa ggttgcgact
    14461 tattggattg aagagtttaa tatcgatgct tggcgtttgg atgtggctaa tgagattgac
    14521 catcagttct ggaaggattt tcgtaaggca gttttagcta aaaatcctga tcttttcgag
    14581 attataaaaa atataaagaa tctagtcata aatttgaatt gaaacaacgt ctttattttt
    14641 tgcttcagca atctaaatcg tttgatgatt ttttagagaa agcaaagcag ttgcatgttc
    14701 agattgattt tagtcaaaag catagccgtt ttttgatgac agatagaacg atgataaaac
    14761 caattcgagg gcgccaactc agcaaacgag atctatatga tgaagaattt tttagaacgc
    14821 attttgctaa gcaagagatt gaaagtcgtt tagaattttt gttaaaccgt gtcaattctt
    14881 tagaagattt aataacaaaa gcaaaagaat tgaatctaac cattgactta aaacaaaaaa
    14941 tgtaactttt atcctggaag aaaataatca aaagataagt ttgggtcatc aaaaaataag
    15001 tgataagaaa ttatatgatg tcaaattttt tcaagattat tttaaaaata aggaagtcgt
    15061 tgcttcagaa ggattagaga atttacagga acagtaccat gctttccaag aagaacgaga
    15121 taaggataaa gtatccactg aagagattga gaaagccttt aagacattta aggaaaaatg
    15181 agataccgtt cgtgaatttg aagtggaact tgcagagaac caaatagaga agctagttga
    15241 taagggcgtc tatatcaagg tgtctttcgg tgtcaaacag agcggtctta ttttcattcc
    15301 caactatcaa ttggatatta tggaagaaga aaatcataaa aaatataaag tctacattcg
    15361 agaaacgtct tcttactttg tctataataa agaaaacatg gataataatt gtttcatcaa
    15421 gggtaggacc ttaatcagac aattgagcaa cgatagccaa aaactcccct atagacgacc
    15481 aactttaaaa agtcttcaag agaagatttc tgaaattaat cttatgattg aactatctaa
    15541 cacgaacaaa caataccaag aaatcaaaga tgagcatgta ttagaaattg cagagattga
    15601 tatgaagcta gaagaaaccc aagaaaaaat cgccacctta aacaagatgg cggaagtcct
    15661 tatcaatttg aagagtgaag atcatgagac tagaaaatta gctaagtatg attttgacca
    15721 aatgaacatg acggaatcaa taatgttaga tcgactcaat acagatattt taaaattaca
    15781 acaggaactt ggtaatgaaa ttaataaata tgaggagata gctagaagat tggatttgtt
    15841 tgtgaaaatt attaatacca ataaatttac agttctaaaa tttcacgaga atgccttact
    15901 agaataatat tatttacgac taattagtta aaagatagag aatcatttca tttattgttt
    15961 acaagtttat caaaatggct agtatagtgt aattttaact tgtcttctcc taaaatatcg
    16021 agaacttgta tagcttgttt cattgtttca ataccactac ttaattgacg tttaaattca
    16081 tagtaaccgg ttgcatagag aaaaactgtc tgttcataaa agtttaattc attctctaac
    16141 aatcccttta tctcattaat taaataagag caattagaaa attcttcttt atctatgctg
    16201 agaatgaaac aatttatagc tagctgagtg acaatccgct tatt
//
LOCUS       DBERDS010000044        14620 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.044, whole genome shotgun sequence.
ACCESSION   DBERDS010000044 DBERDS010000000
VERSION     DBERDS010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14620
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.044"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            237..1682
                     /gene="cps4A"
                     /locus_tag="ACL73E_001623"
     CDS             237..1682
                     /gene="cps4A"
                     /locus_tag="ACL73E_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGS0801562.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLVAYKSLIAGETKAIVLNSVFENIIELEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTSRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVLLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EVLKNYSTIINSLQDSIQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYMMEIDDSSLAVVKAAIQDVMEGR"
     gene            1684..2415
                     /gene="cps4B"
                     /locus_tag="ACL73E_001624"
     CDS             1684..2415
                     /gene="cps4B"
                     /locus_tag="ACL73E_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGS0801563.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAESFLQVREIAKEVADDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALGNNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQNLVHVIASDMHNLDGRPPHMAEAYDFVT
                     QKYGEAKAQELFIDNPRKIIMDQLI"
     gene            2424..3116
                     /locus_tag="ACL73E_001625"
     CDS             2424..3116
                     /locus_tag="ACL73E_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HGS0801564.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKSGLTNQDLQAGSYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVTVPTDTRIVSISVKDKQPEEASRIANSLREVAVERIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELFDTRVKRPEDVEDVLQIP
                     LLGLVPDLDKMK"
     gene            3126..3815
                     /locus_tag="ACL73E_001626"
     CDS             3126..3815
                     /locus_tag="ACL73E_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGS0801565.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNSLCMNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIALAFARAGYKTLLIDGDIRKSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVNKYGSY
                     GNYGDYGKNKK"
     gene            3830..5197
                     /locus_tag="ACL73E_001627"
     CDS             3830..5197
                     /locus_tag="ACL73E_001627"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGS0801566.1"
                     /translation="MNGKVVNSSLAIIHSFLVILLTYLLSAVREAEIASATAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVIFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSVVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTM
                     QGGMFKVDDDPRITKVGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            5184..5681
                     /gene="pssD"
                     /locus_tag="ACL73E_001628"
     CDS             5184..5681
                     /gene="pssD"
                     /locus_tag="ACL73E_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssD/Cps14F family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HGS0801567.1"
                     /translation="MERSKGMKNKKKVCFCASSGGHYEQLMKLEPIMRQQDSYLITEY
                     TDYNKGESEKKDINKVFYLLQINRLEFFWIVKLIWISLKSLYILLRIRPKVVICTGVL
                     AMIPFCLLSKMFGAKLIYIESFAKVTTPTLTGRILYRYADRFYVQWESMLDIYPNAVY
                     KGGLY"
     gene            5682..6161
                     /gene="pssE"
                     /locus_tag="ACL73E_001629"
     CDS             5682..6161
                     /gene="pssE"
                     /locus_tag="ACL73E_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssE/Cps14G family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HGS0801568.1"
                     /translation="MIFITVGTQKHPFNRLLKKIDQLIELEVIKEEVFAQIGASDYKP
                     KYFSYNSFLSSIDMNEKMREASMVITHGGTASIVKALKLRKKIIAVPRLEQFGEHVDN
                     HQLQIITVLGEEGYILPCFDIEQLGTVYQKAQTFTTKPYISNSYALLEDIRQYIDSL"
     gene            6174..7238
                     /locus_tag="ACL73E_001630"
     CDS             6174..7238
                     /locus_tag="ACL73E_001630"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGS0801569.1"
                     /translation="MTKVLQIGPSINLSKGGMSAVIRDLTYSPLLSGDFDITAYQSFI
                     DGSLVTRLTYSSYALLKFVVHSGNYDIYHIHTATRGSCWRKLLYLKLLKSKNKKAILH
                     IHGAEFQIFYDSLPEYKKNKVREMLELSDYVIVLSQTWYDFFSNININAKIVIVENGV
                     DTSFYVEKKKSITSNNFLFLGRMGKRKGAYDLIDAMNQAVAINPNLHLTMAGDGELED
                     IRQKISNLNLTDHITIYDWVNQRDKKILFQANQTLILPSYNEGLPMAILEAMASGLAI
                     ISTPVGGIPEIIHEDNGWLIQPGDISQLSNIILEASYNPDVVSLMGSNNHKLVEEKYS
                     FHSMHGKIKKIYNTLLETKK"
     gene            7238..8698
                     /locus_tag="ACL73E_001631"
     CDS             7238..8698
                     /locus_tag="ACL73E_001631"
                     /inference="COORDINATES: protein motif:HMM:NF014051.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HGS0801570.1"
                     /translation="MTKKSITRNFIFNTILTMSSFIFPLISFPYVSRVLMADGLGRVT
                     FASSIIDYALTFAMLGMPLYGVKVCAGYIKNKEKLSQTVRELLVINLLVGFLVMLLLA
                     TMVIIIPRFRQEWQLIIITSSTIPLNIIGIEWLYKALEDYSYISIRTLTFKILGFLLM
                     FLVVRTKDDYMVYAAITVLASHGSFILNFFRSRTFLLENISQRLNLKQHIKPLLILFF
                     LSVSWTIYKNTDVVMMGFLTSDTEIGYYSTALKIRSIVLSVVTSLGTVVLPRLVKYYK
                     EGKYNEAKKILNKSSSFIMLSSLYFIGYIVINAREIILFIAGRNYLGAIPTLQVSIFS
                     AIFVGYSIMYGTNILVSIGKENVTIQASIIGVVLNICLNFIMIPKFAALGAGIATSIG
                     EAVMVLYEIIYLGKDGWSYFERLNILKIIVVFIFSTFMLYIMKDFFVGYPLFIYIVIS
                     GVIYSIIYIFGLMILRENLLSSWKISILNRFNIIKE"
     gene            8711..9439
                     /locus_tag="ACL73E_001632"
     CDS             8711..9439
                     /locus_tag="ACL73E_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 32 protein"
                     /protein_id="HGS0801571.1"
                     /translation="MIPKKIHYIWFGGSEKPDVVLKCINSWKKYMPDYEIVEWNEDNF
                     DLSDSQFAKSAYESRKWAFASDYARFKILSKYGGIYFDTDVELLKTIPDDILAHSSFT
                     GFEYIGEVNPGLVYACMPDDKIAKYMVQYYEQASFDINHLVTVNTIITDYLLKNNFQK
                     NNQFQIIDGLAIYPDDYFCGYDQEVKEVRLTERTISIHHYSATWKTRTLKRKVQMIVK
                     TIIGAENYRKLLYCKRKITNAVSK"
     gene            9423..10586
                     /gene="cap8K"
                     /locus_tag="ACL73E_001633"
     CDS             9423..10586
                     /gene="cap8K"
                     /locus_tag="ACL73E_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase Cap8K"
                     /protein_id="HGS0801572.1"
                     /translation="MPYLNNVPQNKFSIRLFDIAIVLLTLKMLVSSIPVFDFVFPQKF
                     QNILVILGYILIFLHIFEKRKYTLQFIISIILITTLLLYTSIQMQNYVYFTSWFMLIG
                     TIHYDLRRVIKIIFIVSLSIMFISIFISLLMYIIDYKREILINIRRNETVRAFTFGFI
                     HPNKFTIVLSNLCLMFIWLIKDRLKYYHVTFCLFIQLFFYFFTQTRTALLVSIVIFAL
                     LYIYMFVENLELRWIGYSFFCISTFLGVLAFQFYPSNNKFSIFIDNILTGRIKLAAYA
                     RTFFGYTFWGQYVDKEIVWDPIWGLTSFTFDSFYSFLMSNAGIIWLLILSVLFVKLQK
                     YLDNKSLILLLAWSMYAVTETDLIFPSYGFQFLFLSILFTNTSTCSTIMLKNN"
     gene            10655..11893
                     /locus_tag="ACL73E_001634"
     CDS             10655..11893
                     /locus_tag="ACL73E_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGS0801573.1"
                     /translation="MKIAVTGTGYVGLSIAVLLAQHHQVIAVDIIPEKVELINQRKSP
                     IQDDYIEKYLAEKDLNLVATLDAKEAYKDADFVVIAAPTNYDPKKNFFDTSAVESVIE
                     TVLKYNPDAIMVIKSTVPVGYTESARKKFQTENILFSPEFLRESKALYDNLYPSRIIL
                     GTDKNNERLVSVAETFAGLLQEGALKEDIDTLYMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDVPE
                     ELIGAIVRSNSTRKDFIADQVLKMVDYYDYSAHNVFNERVEKDIIIGIYRLTMKSNSD
                     NFRQSSIQGIMKRIKAKGVRVVIYEPTLESGSTFFGSSIINDLEEFKRLSNAIVANRY
                     DNSLEDVKEKVYTRDIFERD"
     gene            12469..14451
                     /locus_tag="ACL73E_001635"
     CDS             12469..14451
                     /locus_tag="ACL73E_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0801574.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVDLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMIPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT         4769 a         2179 c         2899 g         4773 t
ORIGIN      
        1 cattgtgtac tatagtagat tgaaactaga atagtacaca tctgcttcta aaacattgtt
       61 agaaatcgat ttgactgtcc cgatcgattt gtcatgttct tatttcattt tactatattt
      121 ttgttttgcg ggaagtctac taagatactt aaagatgcag atagtgaaaa aaaggtgtag
      181 acattaccgt aaaaaagtga tataatcgta agatgttcaa tgtataggtg ttaatcatga
      241 gtagacgttt taaaaaatca cgttcacaga aagtgaagcg aagtgttaat atagttttgt
      301 tgactattta tttattgtta gtttgttttt tattgttctt aatctttaag tacaatatcc
      361 ttgcttttag atatcttaat ctagtggtaa ctgcgttagt cctactagtt gccttggtag
      421 ggctactctt gattatctat aaaaaagctg aaaaatttac tatttttctg ttggtgttct
      481 ctatccttgt cagctcagtg tcgctctttg cagtacagca gtttgttgga ctgaccaatc
      541 gtttaaatgc gacttctaat tactcagaat attcgctcag tgtcgctgtt ttagcagata
      601 gtgagatcga aaatgttacg caactgacga gtgtgacagc accgactggg actgataatg
      661 aaaatattca aaaactacta gctgatatca agtcaagtca gaataccgat ttgacggtcg
      721 accagagttc gtcttacttg gttgcttaca agagtttgat tgcaggggag actaaggcca
      781 ttgtcctaaa tagtgtcttt gaaaatatca tcgagttaga gtatccagac tacgcatcga
      841 agataaagaa gatttatacc aagggattca ctaaaaaagt agaagctcct aagacgtcta
      901 agaatcagtc tttcaatatc tatgttagtg gaattgacac ctatggacct attagttcgg
      961 tgtcgcgatc agatgtcaat atcctgatga ctgtcaatcg tgataccaag aaaatcctct
     1021 tgaccacaac gtcacgtgat gcctatgtac caatcgcaga tggtggaaat aatcaaaaag
     1081 ataaattaac ccatgcgggc atttatggag ttgattcgtc cattcacacc ttagaaaacc
     1141 tctatggagt ggatatcaat tactatgtgc tattgaactt cacttctttc ttgaaaatga
     1201 ttgacttatt gggaggggta gatgttcata atgatcaaga gttttcagct ctacatggga
     1261 agttccattt cccagtaggg aatgtccatc tagactctga gcaggctcta ggttttgtac
     1321 gtgaacgcta ctcactagcc gatggagacc gtgaccgtgg tcgcaaccaa caaaaggtga
     1381 ttgtggctat ccttcaaaaa ttaacgtcaa ccgaagtact gaaaaattat agtacgatca
     1441 ttaatagctt gcaagattct atccaaacaa atatgccgat tgagactatg atagatttag
     1501 tgaatactca gttggaaagt ggaggtaatt ataaagtaaa ttctcaagat ttaaaaggga
     1561 caggtcggat ggatcttcct tcttatgcaa tgccagacag taacctctat atgatggaaa
     1621 tagatgatag tagtttagct gtagttaaag cagctataca ggatgtgatg gagggtagat
     1681 gaaatgatag acatccattc gcatatcgtt tttgatgtag atgacggtcc caagtcaaga
     1741 gaggaaagca aggctctctt ggcagaatcc tacaggcagg gggtgcgaac cattgtctct
     1801 acctctcacc gtcgcaaggg tatgtttgaa actccggaag agaagatagc agaaagcttt
     1861 cttcaggttc gggaaattgc aaaagaagta gcagatgatt tagtcattgc ttacggggct
     1921 gaaatttact acacaccaga tgttctggat aagctgggaa aaaagcggat tccgaccctc
     1981 aatgatagtc gttatgcctt gatagagttt agtatgaaca ctccttatcg cgatattcat
     2041 agcgccttga gcaagatctt gatgttggga attactccag tcattgccca cattgagcgc
     2101 tatgatgctc ttggaaataa tgaaaaacgc gttcgagaac tgattgatat gggctgttac
     2161 acgcaagtaa atagttcaca tgtcctcaaa ccaaaacttt ttggagaacg ttataaattc
     2221 atgaaaaaaa gagctcagta ttttttagag cagaatttgg ttcatgtcat tgcaagtgac
     2281 atgcacaatc tagacggcag acctcctcat atggcagaag catatgactt tgttacccaa
     2341 aaatacggag aagcgaaggc tcaggaactt tttatagaca atcctcgaaa aattataatg
     2401 gatcaactaa tttaggagaa atgatgaaag aacaaaacac gatagaaatc gatgtatttc
     2461 aattatttaa aaccttgtgg aaacgcaagc taatgatttt attagtggca cttgtgacag
     2521 gtgcgggggc ttttgcatat agcactttta ttgttaagcc agaatatacg agtaccacgc
     2581 gaatttacgt agtgaatcgc aatcaaggag acaagtcggg gctgacaaat caggatttgc
     2641 aggcaggatc ttatctggta aaagactacc gtgagattat cctttcgcag gatgcattgg
     2701 aaaaagtagc gacaaatttg aagttggaca tgccagcaaa aacgttagct agcaaagttc
     2761 aagtgactgt accaactgac actcgtatcg tctcaatctc tgtcaaggat aaacagccag
     2821 aggaagccag tcgtatcgct aattctctac gagaagttgc tgtagaaagg atcgtcgctg
     2881 taacgcgagt atctgatgta acgacacttg aagaagcgcg accagctacg actccttctt
     2941 ctccaaatgt tcgacgcaat tccttgtttg gttttcttgg aggagcagtt gtaacagtaa
     3001 ttgctgttct tttgattgag ttgttcgaca cccgtgtgaa acgtcctgaa gatgttgaag
     3061 atgtactgca aattccactt ttagggctcg ttccagattt ggacaaaatg aaataggagg
     3121 aagttatgcc aacattagaa atctcacagg caaaattgga ttttgtaaaa aaggcagagg
     3181 aatattataa ctctttgtgc atgaacctac agttaagtgg agatggtttg aaagtatttt
     3241 ctatcacttc tgtgaaacta ggagaaggaa aatcaacgac ttccaccaat atcgctttgg
     3301 cttttgcgcg tgcaggttac aaaacgctgc tgattgatgg agatattcgc aaatctgtta
     3361 tgttaggtgt ctttaaagca agggataaga ttacaggcct gacagaattt ttatcaggaa
     3421 ctacagacct atcacaaggg ctttgtgata ccaatatcga aaatctcttt gtaattcagg
     3481 ctggctctgt gtcaccgaat ccgacagctc ttcttcaaag taagaatttc actacaatgc
     3541 ttgaaacctt gcgtaaatat tttgactaca tcattgtaga tactgctcct gtcggtgtcg
     3601 tgattgatgc ggctattatt acgcgaaaat gcgatgcttc tattttagtg acggaggcag
     3661 gtgaaataaa tcgacgggat attcaaaaag caaaagaaca gttggaacac acagggaagc
     3721 cgtttttggg agttgtgttg aataaattcg atacttcagt aaacaaatac ggttcttatg
     3781 gaaattatgg agattacggg aaaaataaaa aatagattga gggatagaga tgaatggaaa
     3841 agtagtaaat tcttcattgg ccataatcca tagttttctt gttattttat tgacttatct
     3901 acttagtgct gtgagagaag cggagattgc ttcagcaaca gctattgcac tttatatcct
     3961 ccattatttt gtcttttata tcagtgatta tggacaggat ttctttaaaa ggggatattt
     4021 gattgaactt gtccagacat tgaaatatat cctattcttt gcactagcga ttagtatttc
     4081 taattttttc ttagaggatc gatttagtat ttccagacga ggcatgattt acttcctcac
     4141 attacatgct ctcttagtct atgtgctaaa cctatttatc aagtggtatt ggaagcgggc
     4201 ttatcccaac tttaaaggaa gtaagaagat tctcctactt acagcaactt ctcgtgtcga
     4261 aaaggtactg gatagattaa tagaatcaaa tgaggttgtt ggggagttgg tagccgtcag
     4321 tgtcttagat aaaccagatt ttcagcatga ttgtttaaag gtagtagcag agggggagat
     4381 agtaaacttt gcgactcatg aggtggtcga tgaagtcttt atcaatcttc caagtgaaaa
     4441 atacaatatt ggagagcttg tctctcagtt tgaaacgatg ggaattgatg taacagtcaa
     4501 tctaaatgct tttgatcgta gtttggcacg taacaagcaa attcgtgaga tggcaggatt
     4561 aaacgttgtg attttttcta caacatttta taagactagc cacgtgattg ctaagcggat
     4621 tattgatatc gtgggtgcat tggtagggct gatactatgt ggtctagtca gtgttgtact
     4681 ggtccctttg attcgaaagg atgggggctc tgctattttt gctcagacgc gtattggaaa
     4741 aaatggtcgc cacttcactt tttacaagtt ccgctccatg tgtgtagatg ctgaggacaa
     4801 aaaaagagaa ctcatggaac aaaataccat gcagggtgga atgtttaagg tggatgatga
     4861 cccacgtatc acgaaagttg gtcgttttat acggaagact agcttggacg agctgccaca
     4921 gttttataat gttctaaagg gagatatgag tttggttggt acacgaccac caacagtgga
     4981 cgagtatgaa cactatactc cagaacaaaa acgtcgtcta agttttaaac ctggtataac
     5041 aggtttatgg caggttagtg gacgaagtga gattaagaat ttcgatgaag ttgtcaagtt
     5101 agatgtagct tatatagatg attggacaat ctggaaagat attgaaatct tattgaagac
     5161 agttaaagtt gtattgatga aggatggagc gaagtaaagg aatgaaaaat aaaaaaaaag
     5221 tatgtttttg tgcttcgtca gggggacatt atgagcaact aatgaagctt gaaccgatta
     5281 tgagacaaca agacagctat ttaatcacag aatatactga ttataacaaa ggagagtctg
     5341 agaagaaaga tataaacaag gtgttttatc ttttgcaaat taatcgtttg gaattttttt
     5401 ggatcgttaa attgatttgg atttccttga aatcacttta tatactgtta agaatacgcc
     5461 caaaagtagt tatctgtaca ggtgttcttg caatgatacc gttttgtttg ctttcaaaaa
     5521 tgtttggggc taaattaatt tatattgaat cttttgcaaa agtgaccact cctactttaa
     5581 caggtagaat actataccgt tacgcagata gattctatgt gcaatgggag agtatgctag
     5641 atatctaccc aaatgctgtt tataaagggg ggctttatta ggtgattttt ataactgtag
     5701 ggactcaaaa acaccctttt aatcgcttgt taaaaaaaat agatcaactt attgaattag
     5761 aagtgataaa ggaagaggtg tttgctcaga ttggagcttc tgattataaa cctaaatact
     5821 tttcttataa ttcatttttg agttcaattg atatgaatga gaagatgaga gaagctagta
     5881 tggtaattac acatggtggg actgctagta ttgttaaagc tttgaaatta agaaaaaaaa
     5941 ttatagcggt tccacgatta gagcagtttg gagaacatgt ggataatcac caattacaaa
     6001 tcatcacagt tcttggtgag gaaggttata ttttgccatg ctttgatata gagcagttag
     6061 gaactgttta tcaaaaagct cagactttta caacaaagcc atatatttct aatagttatg
     6121 cacttttaga agatatacga caatacatag atagtctttg aaaggaaatt tagatgacaa
     6181 aagttttgca aattgggcct agtataaatt tatctaaagg tggtatgagc gctgttatta
     6241 gagatttgac atatagcccg ttattgtcag gtgattttga tataactgct tatcaatctt
     6301 ttattgatgg ctctcttgta acacggttaa cctattctag ttatgctctt cttaaatttg
     6361 tagttcattc tggtaattat gacatatacc atattcacac tgctacaaga gggagttgtt
     6421 ggagaaaatt actgtatttg aaattactta aaagtaaaaa taaaaaagct attttgcata
     6481 ttcatggagc agaatttcaa atattttatg actcacttcc tgagtataaa aaaaataaag
     6541 ttagagaaat gttagaatta tctgattatg tgattgtact ttcccaaact tggtatgatt
     6601 ttttttcaaa tattaatata aatgcaaaaa ttgtaatagt tgaaaatggt gtagacactt
     6661 ctttttatgt agaaaaaaag aaaagtataa caagcaacaa ctttcttttt ttaggaagga
     6721 tgggcaaaag aaaaggagcc tatgatttaa tagatgccat gaatcaagca gtggctataa
     6781 atcctaattt gcatttgaca atggctggag atggagaact tgaagacata cgtcaaaaga
     6841 tatcaaatct gaatttgact gatcatatta caatatatga ttgggttaat cagagagata
     6901 aaaaaatact atttcaagct aatcagactt tgatattgcc ttcttataat gaggggctcc
     6961 cgatggcaat attggaagct atggcttctg gattagcaat catatcaacg cctgtaggtg
     7021 gcatacctga aattatacac gaggataatg gctggttaat tcaaccgggt gatatttctc
     7081 agttatctaa tattatttta gaagcaagtt acaatcccga tgttgtaagt ttaatgggga
     7141 gcaataatca taagttggtt gaagagaagt atagttttca tagtatgcat ggtaaaatta
     7201 aaaaaattta taatactcta ttagaaacga aaaaataatg actaaaaaat ctattactag
     7261 aaattttatt ttcaatacaa ttctaactat gtccagtttt atttttccac tcatcagttt
     7321 cccatatgtt tcaagggttc tgatggcaga tgggttggga cgagtaacgt tcgcttcttc
     7381 aattattgat tatgccctaa catttgcaat gttagggatg ccattatatg gtgttaaagt
     7441 ctgtgcagga tatattaaaa ataaggagaa gctaagtcag actgtcagag aattgttagt
     7501 cattaattta ttagtaggat ttcttgtgat gcttctttta gcaactatgg taataataat
     7561 tcctcgtttt agacaggaat ggcagcttat tattatcacg tcatctacaa ttcctctcaa
     7621 tattatagga atagagtggt tatacaaagc attggaagac tattcgtata tttcaattag
     7681 aacattgact tttaaaatat taggtttcct tttgatgttt ttagtcgtcc gaacaaaaga
     7741 tgactatatg gtatatgcgg caattacagt tttagctagt catggttctt ttattttgaa
     7801 tttttttaga tctagaactt tcctactaga aaatatctct caaagattga atttaaagca
     7861 acatataaag ccgttattaa ttttattttt tttatctgta tcatggacta tttataagaa
     7921 tacagatgtc gttatgatgg gatttctaac tagtgataca gaaattggtt actattcaac
     7981 agcattaaaa attcgttcta tagtgctcag tgtagtaact tctttaggga cagttgtact
     8041 acctcgttta gtcaaatatt ataaagaagg aaagtataat gaagcaaaga aaatactaaa
     8101 caaaagttct tcatttatta tgctaagttc tttatatttt attggctata ttgtaattaa
     8161 tgccagagaa attattcttt ttattgcggg taggaattac ttaggggcta tcccgacact
     8221 tcaagtatct atttttagtg caatatttgt tggctactct attatgtatg gaaccaatat
     8281 cctagtatct ataggtaaag aaaatgtaac cattcaggca agtattattg gtgttgtttt
     8341 aaatatttgt ttgaatttta ttatgatacc caaatttgct gcactagggg caggtattgc
     8401 aacttctata ggagaagctg ttatggtatt atatgaaata atatacttgg gaaaggatgg
     8461 ttggagctac tttgaaagat taaatatttt aaagattatt gtagtattta tatttagtac
     8521 gtttatgtta tatattatga aagatttttt tgttggctat cctttattta tttatattgt
     8581 aatttcaggg gttatttata gtattatata tatatttggt cttatgatac taagagaaaa
     8641 tttgctttca agttggaaaa tatcaatact aaatcggttt aatattatta aagaatgagg
     8701 agaatattat atgattccta aaaaaatcca ctatatttgg ttcggtggaa gtgagaaacc
     8761 agatgttgtc ttaaaatgta ttaattcttg gaaaaaatat atgccagact atgagattgt
     8821 tgaatggaat gaggataatt ttgatttatc agattcacaa tttgcgaagt ctgcatatga
     8881 atctaggaaa tgggcatttg catcggatta tgctcgtttt aaaattttat ctaagtatgg
     8941 tgggatctat tttgatacgg atgttgagtt gttaaaaaca ataccagatg atatattagc
     9001 tcattcatct tttacaggtt ttgaatatat tggtgaagta aatccaggac ttgtatatgc
     9061 ttgtatgcca gatgataaga tagcaaaata tatggtgcaa tattatgagc aagcaagttt
     9121 tgatatcaat catttggtaa ctgtcaatac aattattaca gattatctat taaaaaataa
     9181 ctttcaaaaa aataatcagt tccaaataat tgatggatta gcaatttatc cagatgatta
     9241 cttttgtggt tatgatcagg aggtcaagga ggttaggctt acggaacgga cgattagtat
     9301 tcatcattat agtgctactt ggaaaacaag aactttaaaa agaaaagtac agatgattgt
     9361 taaaacaatt ataggagctg agaattatag gaaattatta tattgtaaga ggaaaataac
     9421 caatgccgta tctaaataat gtaccgcaaa ataaattttc tataagatta tttgatattg
     9481 ctatagtttt attgacttta aagatgttag tttcttcgat tccagttttt gactttgtgt
     9541 ttcctcaaaa atttcaaaat atccttgtta ttttaggtta tatattgatt tttttacata
     9601 tttttgagaa aagaaagtac acattacaat ttataattag tataattcta attactacat
     9661 tactgcttta tactagtata caaatgcaaa attatgttta ctttacgagt tggtttatgt
     9721 tgattggtac gattcattat gatttaagaa gagtaataaa aattatattt attgtatcat
     9781 taagtattat gttcatatca atttttatat cacttcttat gtatataatt gattataaac
     9841 gagaaattct tattaatatc cgaagaaacg aaactgtcag agcatttaca tttggtttta
     9901 tacatcccaa taaatttact attgtactat ctaacttatg tcttatgttt atttggttaa
     9961 tcaaagatcg tttgaaatat tatcatgtaa ctttttgtct ttttattcag ttattctttt
    10021 attttttcac gcagactaga acagctctac tagtatctat agtaattttt gctcttttat
    10081 atatttatat gtttgttgaa aatcttgaac ttagatggat aggatactca ttcttttgta
    10141 tttctacttt tttaggagtt ttggcatttc aattttatcc ttctaataat aagttttcaa
    10201 tttttattga taatatcctg actggacgta ttaaattagc tgcatacgca agaacctttt
    10261 ttggttatac attctggggt caatatgttg ataaagaaat tgtttgggat cctatttggg
    10321 gattaactag tttcactttt gattcgtttt attccttctt gatgagtaat gctggcatca
    10381 tatggctact tatcttatca gtcttatttg taaaactaca aaaatattta gacaataaaa
    10441 gtttgatttt attattagct tggtctatgt atgcggtaac agaaactgat ttaatatttc
    10501 caagttatgg attccagttc ttatttttaa gtatactttt tactaatact agtacatgtt
    10561 ctacaataat gttaaagaat aattaattga aggaatctat atattttcta atttgtagaa
    10621 tgataggcaa atatatgagg agggaagaaa aagtatgaaa atagcagtaa caggtacggg
    10681 atatgttggc ctatccattg cggttttatt ggctcagcat catcaagtaa tagcggtgga
    10741 cattattcct gagaaggtcg agttaattaa tcaaagaaag tcacctattc aagatgacta
    10801 catagagaaa tatctggcag aaaaggattt aaatttagtg gctacattgg atgcaaaaga
    10861 agcatataaa gatgcggatt ttgttgtgat tgcagctcca actaactatg atccaaagaa
    10921 gaacttcttt gacacttctg ctgtagagtc tgtcattgaa acggtgctta aatataatcc
    10981 agatgctatc atggtcatta aaagtacggt tccagttggt tatacagagt cagctcgaaa
    11041 gaaatttcag actgaaaata tcttatttag tcctgaattt ttgcgtgagt caaaagcact
    11101 ttacgataac ttatatccca gccgtattat tttagggaca gataaaaata atgaacgctt
    11161 ggtaagtgtt gctgagacgt ttgcgggatt gctccaagaa ggcgctttaa aagaagatat
    11221 tgatacattg tacatgggct ttactgaagc tgaggcggtc aagctttttg caaatactta
    11281 cctagctttg cgtgtttctt attttaatga gctggatact tattctgaga tgaaggggct
    11341 agatactcaa gctattattg atggagttgg tttggatcca cgaatcggct ctcactataa
    11401 caatccttcc ttcgggtatg gtggttactg tctccctaaa gataccaagc aacttcttgc
    11461 caactatgaa gatgtaccag aagaacttat aggagctata gtacggagca attcgacacg
    11521 taaagacttt attgccgatc aggttcttaa gatggtagat tattatgatt attcagccca
    11581 taatgttttt aatgagagag tagaaaaaga tattattatt ggtatctata gattgaccat
    11641 gaagagtaat agcgataatt ttcgtcaaag ttctattcaa ggtattatga aacgtataaa
    11701 agctaaggga gtaagagtag ttatttatga accaacttta gaaagtggga gtacattttt
    11761 tggaagttcc attatcaatg atttagagga attcaaacga ctgagtaatg ccattgttgc
    11821 taatcgctat gataactcat tagaagatgt caaggaaaaa gtctatacac gtgatatttt
    11881 tgaaagagat tgatttagta taataaaaat gtaaaaaatt aattgttaga agcggtctat
    11941 actgagaagc aatgggacgc ttagcagatt atacatatta cgatatgcat gttgtgattg
    12001 aacgagcgct cgaagttata gaaaaagagt ttgaaaatga caaaaattag aatcaattgg
    12061 atagattttg gaaaagggtt ctcaatattt ttagttttag tagagcgtct atatcctcca
    12121 ttccccaatt tgtagtatga ttctaattct gatgttgaaa gtgggaatta gctctacttt
    12181 acttcatatt gttatcggaa ttgttttggg ctggcattta tccatcctag caacctatat
    12241 attgaaaaaa attccatttt tgaatattgt tttattacca cagaagtata ttaaattaaa
    12301 ataaattatt ttggctcttt gtcagctaac atctggagag gacaatcacc gtcttctcct
    12361 ttttggtctt ttcagaatat actaaactaa cccaaaaatt ctgaaaattc tgttgacatc
    12421 tttttgaaaa gagtctataa tggagagaaa gttttaaagg agaaaatgat gaaaagttca
    12481 aaactatttg cccttgcggg cgtgacatta ttggcggcga ctactttagc tgcatgctct
    12541 ggatcaggtt caagcgctaa aggtgagaag acattctcat acatttatga gacagaccct
    12601 gataacctca actatttgac aactgctaag gctgcgacag caaatattac cagtaacgtg
    12661 gttgatggtt tgctagaaaa tgatcgctac gggaactttg tgccgtctat ggctgaggat
    12721 tggtctgtat ccaaggatgg attgacttac acttatacta tccgtaagga tgcaaaatgg
    12781 tatacttctg aaggtgaaga atacgcggca gtcaaagctc aagactttgt aacaggacta
    12841 aaatatgctg ctgataaaaa atcagatgct ctttaccttg ttcaagaatc aatcaaaggg
    12901 ttggatgcct atgtaaaagg ggaaatcaaa gatttctcac aagtaggaat taaggctctg
    12961 gatgaacaga cagttcagta cactttgaac aaaccagaaa gcttctggaa ttctaagaca
    13021 accatgggtg tgcttgcgcc agttaatgaa gagtttttga attcaaaagg agatgatttt
    13081 gccaaagcta cggatccaag tagtctcttg tataacggtc cttatttgtt gaaatccatt
    13141 gtgaccaaat cctctgttga atttgcgaaa aatccgaact actgggataa ggacaatgtg
    13201 catattgaca aagttaaatt gtcattctgg gatggtcaag ataccagcaa acctgcagaa
    13261 aactttaaag atggtagcct tacagcagct cgtctctatc caacaagtgc aagtttcgca
    13321 gagcttgaga agagtatgaa ggacaatatt gtctatactc aacaagactc tattacgtat
    13381 ctagttggta caaatattga ccgtcagtcc tataaataca catctaagac cagcgacgaa
    13441 caaaaggcat cgactaaaaa ggctctctta aacaaggatt tccgtcaggc tattgccttt
    13501 ggttttgatc gtacagccta tgcctctcag ttgaatggac aaactggagc aagcaaaatc
    13561 ttacgtaata tctttgttcc accaacattt gttcaagcag atggtaaaaa ctttggcgat
    13621 atggtcaaag agaaattggt cacttatggg gatgaatgga aggatgttaa tcttgcagat
    13681 tctcaggatg gtctttacaa tccagaaaaa gccaaggctg aatttgctaa agctaaatca
    13741 gccttacaag cagaaggtgt gactttccca attcatttgg atatgccagt tgaccagaca
    13801 gcaactacaa aagttcagcg cgtccaatct atgaaacaat ccttggaagc aactttagga
    13861 gctgataatg tcattattga tattcaacaa ctacaaaaag acgaagtaaa caatattaca
    13921 tattttgctg aaaatgctgc tggcgaagac tgggatttat cagataatgt cggttggggt
    13981 ccagactttg ccgatccatc aacctacctt gatattatca aaccttctgt aggagaaagt
    14041 actaaaacat atttagggtt tgactcaggg gaagataatg tagctgctaa aaaagtagat
    14101 ctatatgact acgaaaaatt ggtcactgag gctggtgatg aggctacaga tgttgctaaa
    14161 cgctatgata aatacgctgc agcccaagct tggttgacag atagtgcttt gattattcca
    14221 actacatctc gtacaggtcg cccaatcttg tctaagatga taccatttac aataccattt
    14281 gcattgtcag gaaataaagg tacaagtgaa ccagtcttgt ataaatactt ggaacttcaa
    14341 gacaaggcag tcactgtaga tgaataccaa aaagctcagg aaaaatggat gaaagaaaaa
    14401 gaagagtcta ataaaaaggc tcaagaagat ctcgcaaaac atgtgaaata actgttgcaa
    14461 aatataagaa aggatttagt atttctcttg aatgctgaat ccttttttac atttgtaaag
    14521 aaagattcta aatgtactga cccccaaaag ttggagcctc tttttgtcag aatagagaaa
    14581 atttttgtta attttacttg tttcctattg ctttctcagt
//
LOCUS       DBERDS010000045        14423 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.045, whole genome shotgun sequence.
ACCESSION   DBERDS010000045 DBERDS010000000
VERSION     DBERDS010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.045"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(101..1390)
                     /gene="hisS"
                     /locus_tag="ACL73E_001636"
     CDS             complement(101..1390)
                     /gene="hisS"
                     /locus_tag="ACL73E_001636"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGS0801575.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1468..2715)
                     /locus_tag="ACL73E_001637"
     CDS             complement(1468..2715)
                     /locus_tag="ACL73E_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGS0801576.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLPQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGSQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDRFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            complement(2905..3756)
                     /gene="rgg"
                     /locus_tag="ACL73E_001638"
     CDS             complement(2905..3756)
                     /gene="rgg"
                     /locus_tag="ACL73E_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGS0801577.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYKLNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3880..4221
                     /locus_tag="ACL73E_001639"
     CDS             3880..4221
                     /locus_tag="ACL73E_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGS0801578.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            complement(4520..6223)
                     /gene="ilvD"
                     /locus_tag="ACL73E_001640"
     CDS             complement(4520..6223)
                     /gene="ilvD"
                     /locus_tag="ACL73E_001640"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGS0801579.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6456..7388)
                     /locus_tag="ACL73E_001641"
     CDS             complement(6456..7388)
                     /locus_tag="ACL73E_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGS0801580.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7385..8242)
                     /locus_tag="ACL73E_001642"
     CDS             complement(7385..8242)
                     /locus_tag="ACL73E_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGS0801581.1"
                     /translation="MILSKNREDELRKFAANIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPETFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(8246..9592)
                     /locus_tag="ACL73E_001643"
     CDS             complement(8246..9592)
                     /locus_tag="ACL73E_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0801582.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(9605..9889)
                     /locus_tag="ACL73E_001644"
     CDS             complement(9605..9889)
                     /locus_tag="ACL73E_001644"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0801583.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(9893..11923)
                     /locus_tag="ACL73E_001645"
     CDS             complement(9893..11923)
                     /locus_tag="ACL73E_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGS0801584.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPIIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKVSSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            12114..13121
                     /locus_tag="ACL73E_001646"
     CDS             12114..13121
                     /locus_tag="ACL73E_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGS0801585.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            13124..13324
                     /locus_tag="ACL73E_001647"
     CDS             13124..13324
                     /locus_tag="ACL73E_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGS0801586.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            13475..13657
                     /gene="rpmF"
                     /locus_tag="ACL73E_001648"
     CDS             13475..13657
                     /gene="rpmF"
                     /locus_tag="ACL73E_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGS0801587.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            13673..13822
                     /gene="rpmG"
                     /locus_tag="ACL73E_001649"
     CDS             13673..13822
                     /gene="rpmG"
                     /locus_tag="ACL73E_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0801588.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(14314..>14423)
                     /locus_tag="ACL73E_001650"
     CDS             complement(14314..>14423)
                     /locus_tag="ACL73E_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGS0801589.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         4638 a         3053 c         2484 g         4248 t
ORIGIN      
        1 ttgccgtagg tatggttact gacttcgtca gtttcatcta caacctcaaa acagtgtttt
       61 gagcaacctg cggctagctt cctagtttgc tctttgattt ttattgagta taaaatccta
      121 gtttttcaaa gatttctgag aagttttggc tgattgtctc aagtgacact tgcacttctt
      181 ctcgagtttg gttgttcttg accgtcactt gtccgctttc gacttcgctc tctcctaggg
      241 tgatgagggt cttagccaca aagacatcgg ctgacttgaa ctgagctttt agtttacggt
      301 tgaggtaatc acgctctgct ttgaaacctt gttggcgaag agcctgtacc aattccaagg
      361 ccttgatatt tgccccttcg cccaagactg cgatatagac atctagggcg ttttcgatag
      421 ggagggtcac gccttgtttt tcaaggatga gaagcaggcg ctctacacca agtccaaaac
      481 caaatccagc agtttcaggg cctccaaagt aagcaaccaa accatcgtag cgaccacccg
      541 cacagactgt caagtcattg ccctcaatct ctgtgataaa ctcgaaaatg gtgtggttgt
      601 agtagtccag accacgcacc atattggtat cgatgatgta atctactcca agattttcca
      661 acatctgacg cacagcatca aaatgagttt ggctttcttc atcaagaaag tccaagatag
      721 acggcgcatt ctctactgcc accttgtctt ctttttcctt agagtccaag acacgaagag
      781 gattttcctc caagcgacgt tggctatcct tagacaaggt ctccttgagc ggtgtcaaat
      841 agtcaatcaa ggcttggcgg taggctgcac ggctctcagg atttccaaga gtgttgaggt
      901 gcaatttgac accttgaata ccgatttcct tcaaaaaatg ggctgccata acgattgttt
      961 ccacatcggt agctggattg ctagagccaa aacactcaac accaatctgg tggaattggc
     1021 gcaagcgccc tgcctgtgga cgctcataac ggaacatagg tcccatgtag tagaacttgc
     1081 ttggcttttg cacttctggg gcgaagagtt tattttccac ataggaacgg acaacgggcg
     1141 cagttccttc tggacggagg gtaatatggc ggtcaccctt gtcatagaaa tcgtacattt
     1201 ccttggttac gatatccgtt gtatctccga cagagcggct gataacctcg taatgctcga
     1261 aaataggcgt acgcacttct gcgtagttgt agcgcttgaa aatttcacgg gcaaagccct
     1321 caacgtactg ccacttagca gactcagcag gtaaaatatc ctgcgttcct tttggttttt
     1381 gtaatttcat agggaatcct ctttaaactt aatagtctta ttttaccata aatagaggga
     1441 ttaaaacagt aagaaaaaaa ttaggattta gatatcattt ttgagattaa gaattgttaa
     1501 aaaaatagct agcaaggaaa aaccaacaaa tagcatccaa gtcaactgca tgttccatac
     1561 ggctactagt gaaaaacaag ctgttcccac aggtatggat aaggtaaaca atagaccgaa
     1621 aaaattacta gtacgagcta gaacctctgg agctagattt ttcatgagca tggcactaat
     1681 ctttggttga actttaccag acacatacag agtaaagaag agaaatagca aaccaagcac
     1741 gacttgattg aataaattag ccaaaccaac tagactaagt cctacggtct cccacatcat
     1801 caatctaggc aaggactgct tcccaaaata atcattgccc gtaaggctac tgatgatgat
     1861 tgctactaaa acacagaatt gattgataaa tagtgcctct gtataagaaa aattcaagag
     1921 agaatggctc aaaaagaaga tattataaat tccacccaaa gcgccaccca aggaattaat
     1981 aagcaagaca gcaaagagca taaaaccaaa gtttttctgt ccacttttaa gaaaaacgag
     2041 acgtaaattt cggtaaattg ttaggaaccg gtctttgata gaaagcttct cattttttaa
     2101 gttttcacca tcagcagatg acattgacag gctcaatttg ctttttccta aaaagaggat
     2161 agtggctgat actaggaaaa agcaggcatt gattcccgca acgagagaaa aattattgac
     2221 cgatagagct aagagccaga ctccgaaagc ttgactacca atagctgaaa tataggtgat
     2281 gaactgtgaa aaagaataag cctccatcaa atcatcttca gctacttttt ccttaataag
     2341 aggcatacgc aggccacctg caaaatcact gatgacatca ctaatgacat tgatcaaaca
     2401 caggctagaa aaggcaaaga gactagcttg ctgaacaact agggctgcta gaaaaaatag
     2461 aaccgcctga aacaaaccgc tatagaccat ccatttgacc ttgtccctcg tgtaatctgc
     2521 ccgaatccct gcaaaaactg taaagagggt cggaagaatc atgacaatat tcgccatagc
     2581 aacagcaaaa gatgcttgtg gcaaggtcga tgcatagacg ataaagacca ggttgaaaat
     2641 cgaagcacca aaagcattga agaagcgtga caaagtcaat aggcgataag cttgatttct
     2701 aaacaatagt ttcatagata atctccctcc ttgttctaag ttctacatca agaatagctt
     2761 tagtatagca cttatgaatt tgcgaaacaa ttcttttgaa tatatgcaac aaataaaatg
     2821 agcaaaaaac gatagaactt ttgtaatgac ctgagaaagg gcaacagttc tatcgcttca
     2881 aattttttct tagtttgcag atattcaaca ttcggtcgta tttctatagt attcggcaga
     2941 tttattacag ccaagcatct caaaaatacg gacagcatcc tccatctttt tctggccttc
     3001 cttgactcta ccttgcttgc tatcaaggag accttctgcc cacagataaa caattcggaa
     3061 ataggtctca ttttccttgt agaaatgctc ttcgataaca cgtttaaaat aataggcatt
     3121 ggtaaattct tcacactcaa tactagctaa aaagccattc aatagtatag tatgaaaaag
     3181 gtttcgattg ccagacattt ccattagaaa atcagattta cgtaccattt ctcgtacata
     3241 tctagtaaaa agagaaacag ataaaaatgg agaactgact gaaaataaat tgagtttata
     3301 gattccccag atctcggtag aaaacaaata atcatgaagg acttttcctt cctctgctgt
     3361 taactctacc ctttcatcca tgctcttcat ataagacttg atcataatgg catttagaat
     3421 atgtttctgt ttgttgtgag aatgggcatg cttttgatac tccctgcgat ataagtcctc
     3481 aagaggtgct atattctttg gttccaagac atctgtaatt tcttttctca actcagaatc
     3541 tgtatcatac tggaaacctc tcgccagaaa gaggatctcc tccacactgg cagatatatt
     3601 ttccagagca aatagaaact tttccaccga aagctcactc tgacctgttt caaaacggga
     3661 caacatagac ggcgaaaatt gtcctccggt tgcttgtctc agtgagatat ttcttgattc
     3721 tcgtaattgt ctaaagactt ttccaatctg ctccatagac ttccccttga tcccgtattt
     3781 tcttcatttt atcatatttt tcagaaaatt catcaaaaac ttgccaaatt gtcagaatca
     3841 tgagaaaata gaggatattt atcacgtgga gggactgcta tgagagacga tatcaaaatc
     3901 aatgaccgtg ctttggcctt gcaagaccaa attatcgaaa aactagagaa agtttttgat
     3961 acagatgtgg aattggatgt ttacaatcta ggtctgattt atgaaatcaa tctggatgaa
     4021 acggggctct gcaagattgt catgaccttc accgatactg cctgtgattg cgccgaaagc
     4081 ctgcctattg aaatcgtggc aggtctgaaa caaatcgagg gtatcaaaga tatcaaggtt
     4141 gaagttacct ggtcgcctgc ttggaaaatc acacgaatca gtcgctatgg ccgtattgcc
     4201 cttggactac cacctcgtta agcaggccaa tcacttttaa agatgaaaaa agcaagccga
     4261 aaatggcttg ctttttgata ctcaatgaaa atcaaagggc aaactagaaa actagccgca
     4321 ggttgctcaa aacactgttt tgaagttatg gatagaactg acgaagtcag ctcaaaacac
     4381 tgttttgagg ttgtggatag aactgacgaa gtcagcccaa aacactgttt tgaggttgtg
     4441 gatagaactg acgaagtcag taaccatacc tacggcaagg cgacgttgac gtgatttgaa
     4501 gagattttcg agtatgagtt tattttttac ctgacttgtc catattccag aagtctgtca
     4561 cggctccgcg tgaagcagat gatacgatgt gggcatattt accgaggaca ccacggctgt
     4621 aaagtggtgg caaggttgtt tctgccttgc gtttttcaag ttcttcttcg gatacggcca
     4681 tggaaatttc tttggtatct tggtcaaccg taacgatatc gccggtacgg agataggcaa
     4741 ttggtccacc atcctgagct tcaggagcga tatgtccaac aaccagacca taagtaccac
     4801 cagagaaacg tccgtccgtc aagagggcca ccttatctcc ctgaccttta ccaacaatca
     4861 ttgaagaaag tgacagcatc tcaggcatac caggaccacc tttaggtcca acaaaacgaa
     4921 caacgactac atcgccatca acgatttcat ctgtcagaac ggcctgaatc gcatcttctt
     4981 ctgagtcaaa gaccttagct ggcccaacgt gacgacgcac tttaacacct gataccttgg
     5041 caactgcacc gtcaggagca aggttcccgt tcaagatgat aagcggacca tccgcacgtt
     5101 ttggattttc aagtggcatg ataacttttt ggcctggagt caagtctgca aagtcagcca
     5161 agttttcagc tacagtctta ccagtacatg tgatgcgatc tccgtgaagg aaaccatttg
     5221 ccaacaagta cttcataacc gcagggacac caccgacttc gtagaggtct tggaagacat
     5281 actgaccaga tggtttcaag tcggccaagt gaggcacacg ttcttgaatc gtattgaagt
     5341 cctcaagtga caagtcaaca tttgcggcat gggcaatggc gagcaagtga agagtggcgt
     5401 ttgtagaacc accgagagcc atcgttacag taatagcatc ttcaaaggct tcacgagtca
     5461 agatatctga tggtttgaga ccaagttcca acatcttaac aacagcacgt cctgctgctt
     5521 cgatatcttc tttcttatca gctgattcag ctgggtgaga ggatgaccct ggcaaactca
     5581 tccctagaac ttcgatagca gttgccatgg tattagcagt atacatacca ccacagccac
     5641 cagggccagg gcaggcatta cattcaagac gtttcacgtc ctcagctgtc atgtcaccgt
     5701 ggttccattt tccgatacct tcaaagacag aaaccaagtc gatatcttta ccatcaagat
     5761 ttcccggtgc aatagttcca ccataggcga aaatagctgg gatatccata ttagcaatag
     5821 caatcataga tccaggcatg ttcttgtcac agccaccgat agcgacaaag gcatccacgt
     5881 tgtgaccact catagccgcc tcgatggagt ccgcgatgat gtcacgagat gttagagaga
     5941 aacgcatacc aggcgttccc atagcgatcc cgtctgctac ggtaatggtt ccaaactgta
     6001 caggccaagc gcctgcagat ttgacacctt ctttagccag tttcccgaaa tcatgcaagt
     6061 gaatgttaca tggtgtattt tccgcccaag tcgaaatcac tcccacaatc ggtgtttcaa
     6121 agtccttatc tgtcatacca gtcgcacgaa gcatagcacg gttaggtgat ttaaccatgc
     6181 tgtcataaat gctactgcgg tgacgtttat ctaattcagt catcttatcc ctcccatttc
     6241 agtttttact attatagcac aattttcgca tgaagaacag aataaaaatc ttgaattttc
     6301 agaaaattct atacacatgt gaaatattta aaattaaaaa caacaaagcg gattagtgca
     6361 ctttctgatg accagaatat gctttttaat ccgctttctt taaataacgt actgtaattt
     6421 ttacagaaat tctttcagat aagtgtattt aacatctatc ttgcattata aatttctaga
     6481 accttctctt ttatattcga ttcactcaaa ccatactcat taagaagata atccattttc
     6541 cctacttgac cgaatctttc ttgaacaccc atccgatgaa tttttgtcat tccatcatca
     6601 gagaataatt cacataaaga actgccaatt ccacctatct gattgtggtt ttctacagta
     6661 aatatagttt ttccacttaa cattgttttt atctgttctg gtatcggttt gattctaaat
     6721 aaatctatca cacttactga ataacctaat ttagacagtt catctgcaac tcgaatactt
     6781 ggagcaacca ttataccaga agcaacgatt acaagatctt caccatgcct taactcaatg
     6841 tagcctttag aaaaatcttc tccaccttga tacacaggaa ctggagcttt tctaattgtt
     6901 cgaatatatt ttagtccttt taagtctaat gtctggttca atatttcacg aaattggata
     6961 tcatcagttg cttcaaaaat gatcgattta ggaattaaac gtaacaatcc aatttcttca
     7021 aatggcatat gtgttccacc attcatctct gccgttactc ctgcatctga tccaatcaca
     7081 gtggcatcca attgtgcgta tccaagagaa ataaataatt gatcaaatac tcttcgtgaa
     7141 gcaaaaggac caaatgtatg aagataaggt ctaaacccct gaatagacaa gcctgctgca
     7201 aggccgacca tttctgcttc cataatccca acattcacat aacggtctcc aaaatccttt
     7261 tcaagattat tagtagccat cgaacttgac aaatcggctt ctaagactac tatatcagaa
     7321 taactttgat tagcctctaa aaggaagtct ctatatacat gccgtaattc tttcgtgctt
     7381 ctcatcattc tgtttcctcc aattcctgac ttaatctttc tacaactgaa gttaacattt
     7441 gtctctcctc tacagtaggg cgaagatgat ggttggattt catttcttcc agctcttgaa
     7501 ccccttgacc tttaatagta tctaatacaa tgcacttagg tgatgaatta tttgactgtt
     7561 ttaattggac aatcccttca taaatttctc taatatctga acccttgacc ctaatggatt
     7621 caaatccaaa tgctgaaaat ttttctacga aatcacctgg attacaaata tcctttgtaa
     7681 aaccatctaa ttgttttttg ttatcatcaa caaatacaat taagttggat aactgttgat
     7741 gagaagcaaa ctgtatagcc tcccaacatt gtccctcatt taactcacca tctccaacaa
     7801 tagcataagt ataaaaggga ctctttctta ttctctgacc atatgcaagt ccagttgcaa
     7861 cactaattcc ttgtcctaaa gagcccgttg tcatatctat gcctggcgtt agatttctat
     7921 caggatgaga cggtaatttg gttccatttg tatttaaaga atataagaat tctttgtcaa
     7981 agaaaccatt caaatagagt gtactgtata gagctggtcc tccatgacct tttgataata
     8041 tgaaataatc tctatctcgt gctgcaaatg tttctggagt cattggcatt atttcaccat
     8101 aaagcactgc taaaacttct acgatagaca gacttcctcc gtaatgtccg aatccaagat
     8161 gattcaatgt tctaagagta tttaatcgga tgttagccgc aaattttctt aactcatctt
     8221 ctctattttt acttaaaatc atcccttatt cctcctttgc agatggcttt ttaataaagg
     8281 atactccaaa cataactgct aaaataagaa caagaccaat cacaatgcct gcttgtgagc
     8341 caaattgatt taacattcct aaaataattc ctgatagacc aaaatctgca tctgagaaag
     8401 ttgatccttg gaaaccgagt cctcccaaaa ctggcattaa aaagactggg agaaaactga
     8461 ttaaaatacc ttgtaaaaat gctccaatag tggctccacg aacaccacca gatgcattcc
     8521 caataacacc tgcagtcgct ccacagaaga aatgaggcac aacgcctggt aagataacaa
     8581 ccgttcctga agcaatcata attgccatac ttactaaacc accaataaaa ctagagataa
     8641 atccaattag aactgcatta ggtgcataag tataaacaat cggacaatcc aaagcaggtt
     8701 ttgaattagg tacaagacgc tctgaaatac ctttaaaggc tggaacaatt tcgcccaaaa
     8761 taaggcgaac acctgctaaa ataacaaata cccctgctgc aaattgacct gctaattgta
     8821 aagcataaac tagaccactt gtaccactac tgatttcttt ttctatatat tctgaccctg
     8881 caaagatagc tacaataatg taaataactg ccatagataa agtgatacta acagtactat
     8941 cacgtaaaaa agctaaactc tttggaaatt taatgtcctc tgttgatttt gatttgtcac
     9001 cgataaggct accagtaaaa ccactcaacc aatatcccaa agaactgaaa tgacctaaag
     9061 ccaccttgtc atttccagtt aattgaacca tatatttttg cacaaatgct ggggaaatac
     9121 tcataataat accgagtgct aatcctccta gtaagatgag aggcaagcta gtaaagccag
     9181 caactgataa aatgaccgca atcatacatg ccatatatag agtgtggtgc cctgttaaaa
     9241 aaatatattt aaatcgagta aaacgagcga ttaagatatt gaacaccatt cctgcaaaca
     9301 taatcattgc agtagctgag ccatatgttg ttaaagctac agctacaatt gcttcattat
     9361 tcggcacaac gccagataaa tgaaaagcat gctcaaacat ggtaccaaat ggatttaaag
     9421 aattttgtac aattcctgca ccaccagata caactaagaa accaacaaag gtcttaattc
     9481 cacctttaat aatatcaggt aatttcttct tctgaagaac taatcctaaa attgcaatta
     9541 aagctactaa aatagctggt gtactaacaa tatccaatat gaacttcatc atgacgctag
     9601 cctcctatat aagtcctttt tcttcacaaa gtttagtaat taattctcgt agttcatcca
     9661 tatcaataat actatttaag atacgaacat ctccaagatg actagctgaa tcagctagat
     9721 cacgaccaac aatccaaata tcagctgcat ttggatctgc tccacctaaa tcataatgtt
     9781 caacttctac atccgaaaca ttcaaatcac tcaatacaga ttcaatattc atctgtacca
     9841 taaaacttga acctaatcct gaaccacaag ctgtaccaat ttttaacatt atctaatcct
     9901 cctgtttaat tatcatttta atatcattat agttttttga tgatattaaa gtttgaacat
     9961 gatttttatc tcttaaaatt gttgttaaat gtgacaaagc ctttaaatga ctctcattat
    10021 caatggctgc aatacaaatc aacaatctta cctcttgttc tggattatcc aataaataaa
    10081 tcggttcttc caaaactaac attgacattc ctatttcatt cacaccttca tctggccgag
    10141 cgtgaggaat tgctactccc ttccctaaat taataaaagg tccaaactct tctacttttt
    10201 gaatcattgc ctcagggtag ttctcagtta tcttatcttg atccaaaagc ggtttagctg
    10261 ctaaacgaat cgcctccttc catcctaatt tttgcgaact aacctgatag gtttctttgg
    10321 taataagttg ttctagcact ggtacaattt cctttctatc atttttttga taaagataat
    10381 tctttaacgc caatcttaat tccaattctt gtgtaataat tccatatctt ttgacaatat
    10441 tcaggatttg ttcaatctca aaatctccat actctaaatt cggaaaatct tttaacacta
    10501 gttctactag ttgtattgct tgctcttcag tcatcataac cgaaactaga taatttggct
    10561 tttctgtctc cacctttatg gtagaaaaaa ccatatcata gtcactacta actttcacct
    10621 gtaaatcatc aatctttgag gttcctataa actcaatttg aggaaataat gctaatagat
    10681 tctcttttaa catcaatgaa gaactaacac cattaggaca aatgattgct gctttatacc
    10741 atttttgagg caaagtatct gctttcttta aataacctcc gaaatggata acaaaatatg
    10801 ctgtttcact atcaggtatg ggattgtcaa tagcgtccat caagggcatc aaagaatctt
    10861 tgactaattc aaataaatca ggataatgtt ctttaacatg caatacatat tcatttgaac
    10921 taggtaggcc gaactttaat ctatagtaag ccggtataag gtggcggcga agattttctc
    10981 tcaatccttc cctttgttta aaatgtaaca aagaaatatc ttccattcta cttataatag
    11041 cctctgttaa ttgattaaag taaaccggag caacatctac ttcaccttca aagcaacttg
    11101 ataataaaac ggtgatatag cgataatcat cctcagaaaa caccgtatct ataattccca
    11161 aatcaaccac tgtatccaat aaaatagtcg ttatatcttg aataatagga gatactaatg
    11221 tctctgaaag acacactctt tcaacatccc tttgatacct acacagaatg aatactaaac
    11281 cgaaaaggta aacttttaat tgattaacaa taggtactag ctgtagcttc tcataataat
    11341 ctttaactac ctgatcaatc aaatcataag ttaatgaata cccccaactg gataaaacat
    11401 aatccaaacc ccaaatccct atggaggatt ccagcaactc actaaccatt tgaaaagcta
    11461 agcggtgctt attccactct gaaccgtgta aagtataacc ttttgctcta ctgtacccta
    11521 gctccaaatc attatctaac ataatctttc ttaatgattg aatatcagat aaggttgtat
    11581 tcttacttac tttcaaaaag tcttggtaat gactattcga tataaaatct aatcggcaaa
    11641 aagtgtaaag atagattaaa gctaagcgag tcgactttgg taaaaccaat tcatccgact
    11701 taataatatc tgtcaaagac tgcttcgtac gatttgataa actatagcga ccttgctttt
    11761 tatccagcac tatcccttta ttagctagat aaggcactaa ataatctatt ccttctttga
    11821 cttcctttat aggtaagctc accttaacag ataattcata taatgatagc tcacaatgat
    11881 ccatcaaagt catcaaaata actagtgctc tataatcaaa catctctctt cctttctaac
    11941 tacaattata gtgtaaaaat tataagaata aaagagtatt tgagcacaat ataatctcac
    12001 cttttaaaag aaattattgg gctgaaactt tttagtgatt attttcaact ttctattgac
    12061 ttttaaaaac aaagtgatat catttagata tcaaataatg ggaggtcatt cttatgactg
    12121 aaaaactaat caattcaaaa ccaaatggtg tattcgcatt gattctcatt gagttgacaa
    12181 tcgtacttgg tatctttata tttataatgg gggttggttc ggaaaacatt tttggaatta
    12241 ttatcggacc tttactaatc gtaattgcag gtctagctca tgctggttta aaagttgtca
    12301 aacctcagga agctctggtt ctgacactct ttggtaatta tacaggtacc atcaaagaac
    12361 ctggttttta ctttgtcaat cccttcagcg tagcagtcaa ccctgcaaac cacactcgac
    12421 ttggacaaag tggtgatgtt agcacaaaat ctcctttttt aggagctaaa tcatcaaatg
    12481 acaatgatgt aaatcttgaa attggcaaga aacacatttc cctcaaagtc atgaccttga
    12541 gcaattctcg tcaaaaaatc aatgattgct taggaaaccc tgtagaaatc ggtatcgcgg
    12601 taacttggag agttgtcgat accgctaagg cagtcttcaa cgttgataac tacaaagaat
    12661 atctttcatt gcaatgtgat agcgccctcc gtaatattgt ccgcatctat ccttacgatg
    12721 tgtctcctaa tgtggatact acgggtgacg ggcaagcaga tgaaggtagt ctccgtggct
    12781 ctagcgaaat tgttgctaac cgtattcgtg aagaaatcca aagtcgtgtt gaggatgctg
    12841 gcttggaaat ccttgaagca cgtatcactt acctagctta tgctccagaa attgctgccg
    12901 ttatgcttca acgccaacaa gcatctgcca ttattgatgc acggaagatg attgtagatg
    12961 gtgctgtagg aatggttgaa atggcactag aacggctcaa tgaaggggaa ttggtagaac
    13021 ttgacgaaga acgaaaagct gccatggttt caaatctcct tgtcgttctt tgtggcaatc
    13081 atgatgcaca accaattgtc aacacaggaa gtctttacta aagatggctg aagctaaaaa
    13141 aaagcagatc ccccttcgac tctcaacaaa gttatacgct gcactcgcat catgggcaga
    13201 agacgacttt cgttcagtca atgggcaaat cgaatatctc ctcacagagt gtgtcaagca
    13261 acggaagaaa gacggaaaat acgtatcaga aaccattgac gaaccatttg agattgatat
    13321 ttaacacctt ctcctgtctg ccgtgtcgga taggagaatt ttttcatctt ttttgtcaag
    13381 taactttact ttacaaaaaa aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt
    13441 gaatcgaata taaataccta aaggagaaat caaaatggca gtacctgcac gtcgcacttc
    13501 aaaagcgaag aaaaacaaac gtcgtacaca ctacaaagta acagctccat ctgtaaactt
    13561 tgacgaaact actggagatt actcacgttc tcaccgtgta tcacttaaag gatactacaa
    13621 aggacgtaaa atcactaaag ctgcatcagc tgaataatag aagggagata ccatgcgcgt
    13681 aaatattaca cttgaacaca aagaatctgg tgaacgcttg taccttactt ctaaaaacaa
    13741 acgtaacact ccagaccgcc ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt
    13801 tgtgtttaca gaagttaagt aagcattcaa tacgaatcaa tacagaagaa aaacgcttga
    13861 tcagcgtttt ttctttttgt taatttcact atattgcaag ggaaatcatt cgaatgacta
    13921 catttttcac tacctttttt gaaataagaa tacggattcg gacgattaaa agtaagagaa
    13981 actcaaatgt aagttggggt tccttttttg tatatttttc aaataacgcc tctacactat
    14041 ttgtagcaaa ttcaccaact acagttgtat cttagttaaa ataagttaga atatgtaagt
    14101 gagtaccaga tataccaaga catcgtcacc atctaaggta tattcaaaat acaaaagttg
    14161 accaactaga tttctgaata tccttatata tccattctta aaattggttt aaatagcgta
    14221 gtcttttaaa ctagttttga gaatccaaaa aatcttccta catatgtaag aagatttttt
    14281 agttcagaat gattagattt agctaatgga tacctatcct acccactcac cgttagcatt
    14341 gactcgatag ccatcgggtg tagtcgtgtt tactaataaa tctcctgaat tataggtata
    14401 gtaccattta ccagaaactg taa
//
LOCUS       DBERDS010000046        14350 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.046, whole genome shotgun sequence.
ACCESSION   DBERDS010000046 DBERDS010000000
VERSION     DBERDS010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14350
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.046"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..334
                     /locus_tag="ACL73E_001651"
     CDS             <1..334
                     /locus_tag="ACL73E_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGS0801590.1"
                     /translation="VNYCHDMKLFKMSRRNIGQAGKILADSGYQGPMKIYPQAQTPRK
                     SSKLKPLIAEDKAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAG
                     IINHELGF"
     gene            complement(649..2340)
                     /gene="argS"
                     /locus_tag="ACL73E_001652"
     CDS             complement(649..2340)
                     /gene="argS"
                     /locus_tag="ACL73E_001652"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGS0801591.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2476..2922
                     /gene="argR"
                     /locus_tag="ACL73E_001653"
     CDS             2476..2922
                     /gene="argR"
                     /locus_tag="ACL73E_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0801592.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2973..5507
                     /gene="mutS"
                     /locus_tag="ACL73E_001654"
     CDS             2973..5507
                     /gene="mutS"
                     /locus_tag="ACL73E_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGS0801593.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5654..7348
                     /gene="patA"
                     /locus_tag="ACL73E_001655"
     CDS             5654..7348
                     /gene="patA"
                     /locus_tag="ACL73E_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGS0801594.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMIQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKNVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7498..7929)
                     /locus_tag="ACL73E_001656"
                     /pseudo
     CDS             complement(7498..7929)
                     /locus_tag="ACL73E_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8123..9889
                     /gene="patB"
                     /locus_tag="ACL73E_001657"
     CDS             8123..9889
                     /gene="patB"
                     /locus_tag="ACL73E_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGS0801595.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            10028..10717
                     /locus_tag="ACL73E_001658"
     CDS             10028..10717
                     /locus_tag="ACL73E_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGS0801596.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKHLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10721..10900
                     /locus_tag="ACL73E_001659"
     CDS             10721..10900
                     /locus_tag="ACL73E_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801597.1"
                     /translation="MEHLVVLFFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10887..12236
                     /locus_tag="ACL73E_001660"
     CDS             10887..12236
                     /locus_tag="ACL73E_001660"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGS0801598.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEKIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12360..13820
                     /gene="gltX"
                     /locus_tag="ACL73E_001661"
     CDS             12360..13820
                     /gene="gltX"
                     /locus_tag="ACL73E_001661"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGS0801599.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGTIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13834..14268
                     /locus_tag="ACL73E_001662"
     CDS             13834..14268
                     /locus_tag="ACL73E_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS0801600.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNEQ"
BASE COUNT         4222 a         2762 c         3218 g         4148 t
ORIGIN      
        1 tgtgaactat tgtcatgata tgaagttgtt caaaatgagt cgcagaaata tcggacaagc
       61 tggtaaaatc ttggctgaca gtggttatca agggcccatg aagatatatc ctcaagcaca
      121 aactccacgt aaatccagca aactcaagcc gctaatagct gaagataaag cctataacca
      181 tgcgctatcc aaggagagaa gcaaggtcga gaacatcttt gccaaagtaa aaacgtttaa
      241 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat
      301 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta ttatttggtt
      361 aggtgaatta gtgaagcgtt taggcaagtg tctctggtta cgacgtcatg gcctctaaat
      421 cgattatatt taggggtcat gactagtgaa gcagttagct agttcgcata taagcggcta
      481 gcgtctaaca attaggaact ttagttccaa taactttaag attacgacgt tttaggacat
      541 aaatcgatca tatttatgtc ctaaaactag tgaagcgcct agccaaagtc cgaataggat
      601 ttggcgttag ttacttagat tgctttgcaa tcaagtaact ttggcgattt acatcttctc
      661 tggcgcttct actccaagca agcgaagggc ttctttgaga acgactgcgg ttgcgtagct
      721 gagggctaga cggctgtcgc gttctgggct ttcatccaag atacgtgtat gtgcatagta
      781 tttgttaaag gattgagcca ggctaattgc aaatttagca atgatagaag gttcaaagtt
      841 atctgccgca cggttgataa tacgtgggaa gtcttgaatg agtttaatga tttcccagct
      901 ttcagtatca ttcaagctat agttgccagc tgtttctggt ttgaaatcgg ctttgcgtaa
      961 gatagattgg atacgagcgt aggcatattg aacgtaaggt ccagtttcac cctcgaagga
     1021 taccatagct tctaggtcga agtcgtatcc atttgtacgg tcagttttga ggtcatagaa
     1081 tttaatggct ccaaccccaa cagcatgtgc tacttggtct ttgttttcta gttcaggatt
     1141 tttagcctcg atttggacct tggcacggct aacagcctct gcaacagtag gctctagcaa
     1201 gatgacattc cctttacgag tagagagctt cttcccttct tttgtaacca gaccaaaagg
     1261 aacgtgggta atgtcgtcac tccaatcgta gcccatctct tgcaagacag ctttgagttg
     1321 tttaaagtgg gcagattgct cttgaccaac gacgtagata gatttagcaa attggtattc
     1381 atttttacgg tagagggctg cagccaagtc acgtgtgata tagagagttg caccatcaga
     1441 cttcttgatg agggctggat gttcaattcc atatttctca agattcacaa cttgggcacc
     1501 ttctgattca agaagtagtc ctttttcaga aagaatgtct acaactgcat ccatcttatc
     1561 attgtagaag gcttctccgt tatagctgtc aaattcaacc ttcaattcat tgtaaaggcg
     1621 gttaaattcc actaaacttt catcgcggaa ccattgccaa agagcgagag cttcctcatc
     1681 tccattttca agtttacgga accattcgcg cgcttcttca tccaagctag ggtcattttc
     1741 agcttcagcg ttgatgcgga catagagttt aaggagttca tcgattggat gagcttttac
     1801 agcttcttcg tcgccccatt ttttgtaggc aacaatcaac atcccaaatt gtttacccca
     1861 gtctcccaaa tggttgacct tgaccgtttg ataaccgatt ttttggaaaa tatgtgacaa
     1921 gctatctccg ataacagttg aacgcaggtg gccaatagaa aatggtttag cgatattcgg
     1981 actagacatg tcgataacaa cattttcttg tttgccaata ttttggtcag catagtgttc
     2041 tttttcagtg gtaacagctt gcaatacttg agcagaaatg gcagatttat caaggaaaaa
     2101 gttaacgtaa ggtcctgttg cgacaacttt ttcaaaggct tggctgttca ttttttcagc
     2161 cagttcagcc gcaatcattt gtggtgcttt acgttcgact tttgcaagag aaaaagcagg
     2221 gaaagcaatg tctcccattt ctgagttttt aggggtttcc agtaacttta aaatagcctc
     2281 ttggtccagg ctatcaatga tgctagataa ttcgctagca atcaattctt ttgtattcat
     2341 taagagctcc tttttggact tttctactat tttatcacaa ttttaaagaa agaagaaaaa
     2401 atttttgaaa tctcctgttt ttttggtata atatggttat aaatatagtt ataaatatgc
     2461 acgcaagagg attttatgag aaaaagagat cgtcatcagt taataaaaaa aatgattact
     2521 gaggagaaat taagtacaca aaaagaaatt caagatcggt tggaggcgca caatgtttgt
     2581 gtgacgcaga caaccttgtc tcgtgatttg cgcgaaatcg gcttgaccaa ggtcaagaaa
     2641 aatgatatgg tgtattatgt actagtaaat gagacagaaa agattgattt ggtggaattt
     2701 ttgtctcatc atttagaagg tgttgcaaga gcagagttta ccttggtgct tcataccaaa
     2761 ttgggagaag cctctgtttt ggcaaatatt gtagatgtaa acaaggatga atggatttta
     2821 ggaacagttg ctggtgccaa taccttattg gttatttgtc gagatcagca cgttgccaaa
     2881 ctcatggaag atcgtttgct agatttgatg aaagataagt aaggtcttgg gagttgctct
     2941 caagacttat ttttgaaaag gagagacaga aaatggcgat agaaaagcta tcacccggca
     3001 tgcaacagta tgtggatatt aaaaagcaat atccagatgc ttttttgctc tttcggatgg
     3061 gtgattttta tgaattattt tatgaggatg cggtcaatgc tgcgcagatt ctggaaattt
     3121 ccttaacgag tcgcaacaag aatgccgaca atccgatccc tatggcgggt gttccctatc
     3181 attctgccca acagtatatc gatgtcttga ttgagcaggg ttataaggtg gctatcgcag
     3241 agcagatgga agatcctaaa caagcagttg gggttgttaa acgagaggtt gttcaggtca
     3301 ttacgccagg gacagtggtc gatagcagta agccggacag tcagaataat tttttggttt
     3361 ccatagaccg cgaaggcaat caatttggcc tagcttatat ggatttggtg acgggtgact
     3421 tttatgtgac aggtcttttg gatttcacgc tggtttgtgg ggaaatccgt aacctcaagg
     3481 ctcgagaagt ggtgttgggt tatgacttgt ctgaggaaga agaacaaatc ctcagccgcc
     3541 agatgaatct ggtactctct tatgaaaaag aaagctttga agaccttcat ttattggatt
     3601 tgcgattggc aacggtggag caaacggcat ctagtaagct gctccagtat gttcatcgga
     3661 ctcagatgag ggaattgaac cacctcaaac ctgttatccg ctacgaaatt aaggatttct
     3721 tgcagatgga ttatgcgacc aaggctagtc tggatttggt tgagaatgct cgctcaggta
     3781 agaaacaagg cagtcttttc tggcttttgg atgaaaccaa aacggctatg gggatgcgtc
     3841 tcttgcgttc ttggattcat cgccccttga ttgataagga acgaatcgtc caacgtcaag
     3901 aagtagtgca ggtctttctc gaccatttct ttgagcgtag tgacttgaca gacagtctca
     3961 agggtgttta tgacattgag cgcttggcta gtcgtgtttc ttttggcaaa accaatccaa
     4021 aggatctctt gcagttggcg actaccttgt ctagtgtgcc acggattcgt gcgattttag
     4081 aagggatgga gcaacctact ctagcctatc tcatcgcaca actggatgca atccctgagt
     4141 tggagagttt gattagcgca gcgattgctc ctgaagctcc tcatgtgatt acagatgggg
     4201 gaattatccg aactggattt gatgagactt tagacaagta tcgttgcgtt ctcagagaag
     4261 ggactagctg gattgctgag attgaggcta aggagcgaga aaactctggt atcagcacgc
     4321 tcaagattga ctacaataaa aaggatggct actattttca tgtgaccaat tcgcaactag
     4381 gaaatgtgcc agcccacttt ttccgcaagg cgacgctgaa aaactcagaa cgctttggaa
     4441 ccgaagaatt agcccgtatc gagggagata tgcttgaggc gcgtgagaag tcagccaacc
     4501 tcgaatacga aatatttatg cgcattcgtg aagaggtcgg caagtacatc cagcgtttac
     4561 aagctctagc ccaaggaatt gcgacggttg atgtcttaca gagtctggcg gttgtggctg
     4621 aaacccagca tttgattcga cctgagtttg gtgacgattc acaaattgat atccggaaag
     4681 ggcgccatgc tgtcgttgaa aaggttatgg gggctcagac ctatattcca aatacgattc
     4741 agatggcaga agataccagt attcaactgg ttacagggcc aaacatgagt gggaagtcta
     4801 cctatatgcg tcagttagcc atgacggcgg ttatggccca gctgggttcc tatgttcctg
     4861 ctgaaagcgc ccatttaccg atttttgatg cgatttttac ccgtatcgga gcagcagatg
     4921 acttggtttc gggtcagtca acctttatgg tggagatgat ggaggccaat aatgccattt
     4981 cgcatgcgac caagaactct ctcattctct ttgatgaatt gggacgtgga actgcaactt
     5041 atgacggaat ggctcttgct cagtccatca tcgaatatat ccatgagcac atcggagcta
     5101 agaccctctt tgcgacccac taccatgagt tgactagtct ggagtctagt ttacaacact
     5161 tggtcaatgt ccacgtggca actttggagc aggatgggca ggtcaccttc cttcacaaga
     5221 ttgaaccggg accagctgat aaatcctacg gtatccatgt tgccaagatt gctggcttgc
     5281 cagcagacct tttagcaagg gcggataaga ttttgactca gctagagaat caaggaacag
     5341 agagtcctcc tcccatgaga caaactagtg ctgtcactga acagatttca ctctttgata
     5401 gggcagaaga gcatcctatc ctagcagaat tagctaaact ggatgtgtat aatatgacac
     5461 ctatgcaggt tatgaatgtc ttagtagagt taaaacagaa actataaaac caagactcac
     5521 tagttaatct agctgtatca aggagacttc tttgacaatt ctccactttt ttgctagaat
     5581 aacatcacac aaacagaatg aaaaggagct gacgcattgt cgctcccttt tgtctatttt
     5641 ttaaggagaa agtatgctga ttcagaaaat aaaaacctac aagtggcagg ccttggcttc
     5701 gctcctgatg acaggcttga tggttgctag ttcacttctg caaccgcgtt atctgcagga
     5761 agtattagac gccctcctta ctgggaaata tgaagctatt tatagtatcg gggcttggtt
     5821 gattggtgtg gccgtagtcg gtctagttgc tggtggactc aatgttgtcc tcgcagccta
     5881 tattgcccaa ggagtttcat ccgaccttcg ggaggatgcc ttccgtaaaa ttcaaacctt
     5941 ttcttatgct gatattgaac aatttaatgc gggaaatcta gtcgttcgaa tgacaaatga
     6001 tatcaaccag attcagaacg ttgtcatgat gaccttccaa attcttttca gacttcccct
     6061 cttgttcatc ggttcgttta tcctagcggt tcaaacctta ccttctctgt ggtgggtgat
     6121 tgttctcatg gtagtcttga tttttggttt gactgctgtc atgatgggaa tgatggggcc
     6181 tcgttttgct aaatttcaaa cccttcttga gcgcatcaat gccattgcca aggaaaattt
     6241 acgtggcgtt cgtgtggtca agtcctttgt ccaagaaaaa gagcaatttg ctaagtttac
     6301 agaggtctca aacgagcttc ttggtcaaaa cctttacatt ggttatgcct tttcagtagt
     6361 ggaacccttt atgatgttgg ttggttacgg ggcggtcttc ctctctattt ggctggtcgc
     6421 gggaatgatt cagtcggatc cgtctgttgt tggttccatc gcttcttttg ttaattacct
     6481 aagccagatt atctttacca ttgttatggt tggatttttg ggaaattctg tcagccgtgc
     6541 catgatttcc atgcgtcgta ttcgagaaat tcttgacgca gagccagcta tgaccttcaa
     6601 ggatatccca gatgaagagt tggttggaag tcttagcttt gaaaatgtga cctttaccta
     6661 tccaatggac aaggaaccga tgctgaaaaa tgtgagcttt actattgaac ctggtcaaat
     6721 ggttggtgta gttggagcga ctggtgcagg aaagtcaacc ttggctcaat tgattccacg
     6781 tctctttgat ccacaggacg gggccattaa aattggtggc aaggatattc gagaagtgag
     6841 tgaaggaacc ctgcgtaaaa cagtttccat cgttctccaa cgtgccattc tttttagtgg
     6901 aacgattgca gataacttga gacaggggaa gggaaatgct accctatttg aaatggagcg
     6961 cgcagccaat attgcccagg ctagtgaatt cattcatcgt atggagaaaa cctttgaaag
     7021 tccagttgaa gaacggggaa ccaatttctc tggtggacaa aaacaaagga tgtcgattgc
     7081 gcgtgggatt gtcagcaatc cacgtattct gatttttgac gattcgacct cagccttgga
     7141 tgccaaatca gagcgcttgg tgcaagaagc tttgaataag gacttgaagg ggacgacaac
     7201 cattattatt gctcaaaaaa ttagctcggt tgtccatgca gacaagatct tggttctaaa
     7261 tcaaggacga ttgattggtc aaggtacgca tgcagacttg gttgccaaca atgccgttta
     7321 ccgtgaaatc tatgaaacac agaaatgaaa gacaaactat aagaaaagtc aatagtttta
     7381 tctaaactat ttcttatttc aatttgatga tttggcgatg attttagagc acggcaaaaa
     7441 gcccttgaaa aagtccattt tttcaaaggt aatcctgtgt tgatttcaga aattacatca
     7501 ctttttgttc gtcaaatggc agctcttttt taggatataa aacagggttc ggataagttt
     7561 ttttgcaagg tggatgatgg ctacattgta atgttttcct tgttctaact tagtcttaaa
     7621 agcaggtgaa aagtgagggc atgctttggc agcttgtatg agtacctacc gcagatgagg
     7681 ggaaccccgt ttgaccattc tttctgctaa atcaatctga cctgactgat aaatagaaga
     7741 atccagtcca gcgaaagctt gtaattgagc aggattatca aaggcatgaa tatttcgaat
     7801 ctcggctaaa atgaccgccc ctaaacgatt ctcaatccca gtaaccgtcg tgatgaccga
     7861 gttgaactca gccatcaagt cattgacaca tttttccgcc ttgtcactga gcctcttgta
     7921 atgtttgatg ttttcattac acgagataaa acgtctatgc gttatcaaac tcattaccaa
     7981 ttaaaacaaa tgtggttaga tcctttcgga aattgtcaag cgattggagg aaatgaacta
     8041 atccacagcg gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa
     8101 atataatata aggaggagta aaatgaagac agttcaattt ttttggcatt attttaaggt
     8161 ctacaagttc tcatttgtag ttgtcatcct gatgattgtt ctggcgactt ttgcccaagc
     8221 cctctttcca gtcttttctg gacaagcggt gacgcagcta gccaatttag ttcaagctta
     8281 tcaaaatggc aatccagaac ttgtatggca aagcctatca ggaatcatgg tcaatcttgg
     8341 cctgctggtt ttggttctat ttatctctag tgtaatatac atgtgtctca tgacgcgcgt
     8401 gattgcagaa tcgaccaacg agatgcgcaa aggtctcttt ggtaagcttg ctcagttgac
     8461 ggtttctttc tttgaccgtc gacaagatgg cgatatcctg tctcatttta ccagtgattt
     8521 ggataatatc ctccaagcct ttaacgaaag cttgattcag gtcatgagca atattgtttt
     8581 atacattggt ctgattcttg tcatgttttc gagaaatgtg acgctggctc tcatcactat
     8641 tgccagcacc ccattggctt tccttatgct gattttcatc gtgaaaatgg cacgtaaata
     8701 caccaacctc cagcagaaag aggtagggaa gctcaacgcc tatatggatg agagcatctc
     8761 aggccaaaaa gccgtgattg tgcaaggaat tcaagaggat atgatggcag gatttcttga
     8821 acaaaatgag cgcgtgcgca aggcaacctt taaaggaaga atgttctcag gaattctttt
     8881 ccctgtcatg aatgggatga gcctgattaa tacagccatc gtcatctttg ctggttcggc
     8941 tgtacttttg aatgataagt ctattgaaac aagtacagcc ctaggtttga ttgttatgtt
     9001 tgcacaattt tcacagcagt actaccagcc tattatccaa gttgcagcga gttggggaag
     9061 ccttcagttg gcctttactg gagctgaacg aattcaggaa atgtttgatg cagaggagga
     9121 aatccgacct gaaaaggctc caaccttcac taagttgcaa gaaagtgttg aaatcagtca
     9181 tatcgatttt tcatacttgc ctgataaacc tattttgaaa gatgtcagca tttctgcccc
     9241 taaaggccag atgacagcag ttgttgggcc gacaggttca ggaaaaacga ctattatgaa
     9301 cctcatcaat cgcttttatg atgttgatgc tggtggtatt tattttgatg gtaaagacat
     9361 tcgtggctat gacttagata gtcttagaag caaggtggga attgtattgc aagattcggt
     9421 cttgtttagc ggaacgattc gagacaatat ccgatttggt gtgccagatg ctagtcagga
     9481 aatggttgag gtagcagcaa aagcaaccca cattcacgac tatatcgaaa gtttgcctga
     9541 taagtacgat actcttattg atgatgacca gagcatcttt tcaacagggc agaagcaatt
     9601 gatttcaatc gctcgaaccc tgatgacaga tccagaagtt ctcattctcg atgaagcaac
     9661 ttcaaacgta gatacggtga cagaaagcaa gattcagcat gccatggagg tggttgtagc
     9721 aggtagaact agtttcgtca ttgcccaccg cttgaaaacc attctcaatg cagatcagat
     9781 tattgtcctt aaagatggag aagtcattga acgtggtaac caccatgaac ttttgaagct
     9841 aggtggtttt tattcagaac tctatcacaa tcaatttgtt ttcgaataag aaagaagttg
     9901 tcctatgtgg gcagcttttt cttgtccata aaaaatgttt atcacagcct taaaaaaaac
     9961 atattagacg aaagtcattt tgagtgatat gataggacta tcgttagcat tcgaaaggag
    10021 aggcatcatg gctagaacgg ttgtaggagt tgctgcaaat ctatgtcccg tagacgcaga
    10081 aggcaaaatc attcattcat ctgtatcttg tagattcgca gagatcattc gtcaagtcgg
    10141 tggtctccct ttagtcattc ctgttggtga tgagtcagtt gtacgtgatt atgtggaaat
    10201 gattgacaaa ctcattttga caggaggcca aaatgttcat cctcagtttt atggagagaa
    10261 aaagaccgtc gagagcgatg attacaatct ggtccgtgac gaatttgaat tggcactctt
    10321 gaaggaagcg cttcgtcaga ataaaccaat tatggcaatc tgtcgcggtg tccaacttgt
    10381 caatgttgcc tttggtggaa ccctcaatca agaaatcgaa ggtcactggc aaggactacc
    10441 tttcgggaca tctcactcta ttgagacagt agaaggaagc gtggtggcta agctatttgg
    10501 gaaagaaagt caggtcaact cagtccatcg tcaaagcatt aaacatttgg cacctaattt
    10561 ccgtgtaact gctattgatt caagagacca aactattgaa gcgattgagt ctatcgacga
    10621 gcaccgcatt atcggtttac agtggcatcc agagtttctg gttaatgaag aagatggcaa
    10681 tttagaatta tttgagtatt tattgaatga actgtaacga ttggaacatc tggtcgttct
    10741 tttttttatt ttttcaaaat ttttagaatg tggtatttta cgcaaacgtt tgaattctga
    10801 taaaaattgg agaaattcga caaaaaaact tgaaaaaaac gaaggtaagc gttatgatag
    10861 aaaagaagaa atattggagg aagaacatgt cacatattaa atttgattat tcaaaagttt
    10921 tagacaaatt tgttgcacca catgaagtgg aatacatgca atcacaagta acagcagcag
    10981 atgaattgat ccgtaaagga actggtgctg gtagcgactt cttgggatgg ttggaccttc
    11041 ctgaaaaata cgatcgcgaa gaatttgacc gcatcttgaa agctgctgag aaaatcaagt
    11101 cagacagcga tgttttggtt gtgatcggta ttggtggatc ttaccttggt gcaaaagcag
    11161 caatcgactt cttgaatcac cattttgcta acttgcaaac aaaagaagaa cgcaaagctc
    11221 cacaaatcct ttacgcagga aactcaatct catctactta ccttgctgac ttggtagagt
    11281 atgttgcaga caaggacttc tcagtaaacg taatttctaa atcaggtaca acaactgaac
    11341 cagcgattgc tttccgtgtc tttaaagaac tcttggttaa gaaatacggt caagaagaag
    11401 ctaacaagcg tatctatgca acaactgacc gccaaaaggg tgctgttaag gttgaagcag
    11461 acgctaacgg ttggggaaca tttgttgttc cagatgatat cggtggacgc ttctcagtat
    11521 tgacagccgt tggtttgctt ccaatcgcag catcaggagc tgacatcaaa gctcttatgg
    11581 aaggtgcgaa tgcagctcgc aaagactaca cttcagacaa aatctctgaa aacgaagctt
    11641 accaatacgc agccgttcgt aacatccttt atcgtaaagg ctatgcaact gagatcttgg
    11701 taaactatga gccatcactt caatacttct cagaatggtg gaaacaattg gctggtgaat
    11761 cagaaggaaa agaccaaaaa ggtatctacc caacttcagc caacttctca actgacttgc
    11821 actcacttgg tcaatttatc caagaaggaa ctcgtatcat gtttgaaaca gttgtccgtg
    11881 ttgacaaacc tcgtaaaaac gtgcttattc ctactttgga agaagacctt gacggacttg
    11941 gttaccttca aggaaaagac gttgactttg taaacaaaaa agcaactgac ggtgttcttc
    12001 ttgcccacac agatggtgat gtaccaaaca tgtatgtgac tcttccagag caagacgctt
    12061 tcactcttgg ttacactata tacttcttcg aattggcaat tgccctttca ggttacttga
    12121 atgctatcaa cccatttgac caaccaggtg ttgaagctta taaacgtaac atgtttgccc
    12181 ttcttggaaa accaggattt gaagaattga gcaaagaact taacgcacgt ctataataga
    12241 agaaaagagt ggtttgccca ctctttttac tctctttatc catagaaatt ggactcagcc
    12301 aagacttgtg atataatata gaaagcaaaa aggcagacgc ctagataata ggagaaacta
    12361 tgtcaaaaga tatccgcgta cgttacgcac caagtccaac aggactacta cacatcggaa
    12421 atgctcgtac agcattgttt aattacttgt atgcgcgcca tcatggtgga acatttctca
    12481 tccgtatcga agatactgac cgtaaacgcc atgtcgagga tggtgaacgt tcacaacttg
    12541 aaaaccttcg ctggttaggc atggattggg atgaaagtcc agaatcacat gagaattatc
    12601 gccagtctga gcgtttggac ttgtatcaaa aatacatcga ccaactatta gctgaaggaa
    12661 aagcctacaa atcttacgtt acagaagaag agttggcagc tgaacgtgaa cgtcaagaag
    12721 tagctggcga aacaccacgc tacatcaatg aataccttgg tatgagtgaa gaagaaaaag
    12781 cagcttacat cgcagaacgt gaagcagcag ggaccatccc aactgttcgt ttggctgtca
    12841 atgagtcagg tatctacaag tggcatgata tggtcaaagg cgatatcgaa tttgaaggtg
    12901 gcaatatcgg tggtgactgg gttatccaaa agaaagacgg ttacccaact tacaactttg
    12961 ccgttgttat cgatgaccac gatatgcaaa tctctcatgt tatccgtgga gatgaccata
    13021 ttgctaatac accaaaacag cttatggtct atgaagctct tggttgggaa gctccagagt
    13081 tcggtcacat gaccttgatt atcaactctg agactggtaa gaagttatct aaacgtgata
    13141 ctaatacact tcaatttatc gaagattacc gaaagaaagg ttaccttcca gaagcagtct
    13201 ttaattttat tgctcttctt ggttggaacc caggtggtga agatgagatt ttctctcgtg
    13261 aagaactcat taaacttttt gatgaaaacc gcctcagcaa gtcaccagca gcctttgatc
    13321 agaaaaaact agactggatg agcaatgatt atatcaagaa tgcagacctt gaaaccatct
    13381 ttgaaatggc aaaaccattc ttagaggaag caggccgttt gactgacaag gctgaaaaat
    13441 tagttgagct ctataaacca caaatgaaat cagtagatga gattatccca ttgacagatc
    13501 ttttcttctc agatttccca gaattgacag aagcagagcg cgaagtcatg acgggtgaaa
    13561 cagttccaac agttcttgaa gcattcaaag caaaacttga agcgatgaca gatgataaat
    13621 ttgtgacaga aaatatcttc ccacaaatta aagcagttca aaaagaaaca ggtattaaag
    13681 ggaaaaatct tttcatgcct attcgtatcg cagtttcagg cgaaatgcat gggccagaat
    13741 taccagatac aattttcttg cttggacgtg aaaaatcaat tcagcatatc gaaaacatgc
    13801 taaaagaaat ctctaaataa agaggataca ataatggaca tctgggaaaa gatgtacgaa
    13861 gaagcacaga aactatacaa tccacatgaa gtatcagact ttgtttatgc caatcatgtt
    13921 gtagctgcag tagaagcaga agatggacaa atatttacag gattctgtat ggagggaacc
    13981 tgtggtgttt tccatctctg cgcagaacgg gcggccctct tcaatatgta ccaattttca
    14041 ggacaaacta aggttaagaa agtattagcc tttcgagata aaccacctta tggtggaagt
    14101 tcagccatgc cttgcggtgc ttgtagagaa ttccttttag agcttaatgc tgaaaataaa
    14161 gatgcagaat tcatgatgga ctataatata agaaaaacag ttaaagtcgc agaactaatc
    14221 ccttattggt ggggagaaga acgtgcttct aagtttaatg agcaatagaa gagtcagtat
    14281 aattctggct ctttttacta taagtttcaa aaaaaatgaa aaaaattaga aaaagtagtt
    14341 gacaaagttt
//
LOCUS       DBERDS010000047        13447 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.047, whole genome shotgun sequence.
ACCESSION   DBERDS010000047 DBERDS010000000
VERSION     DBERDS010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.047"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            192..1370
                     /locus_tag="ACL73E_001663"
     CDS             192..1370
                     /locus_tag="ACL73E_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS0801601.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1598..2044)
                     /locus_tag="ACL73E_001664"
     CDS             complement(1598..2044)
                     /locus_tag="ACL73E_001664"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801602.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            2114..2773
                     /locus_tag="ACL73E_001665"
     CDS             2114..2773
                     /locus_tag="ACL73E_001665"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGS0801603.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2825..3976)
                     /locus_tag="ACL73E_001666"
     CDS             complement(2825..3976)
                     /locus_tag="ACL73E_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0801604.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(3991..4722)
                     /locus_tag="ACL73E_001667"
     CDS             complement(3991..4722)
                     /locus_tag="ACL73E_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801605.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            4951..5052
                     /locus_tag="ACL73E_001668"
                     /pseudo
     CDS             4951..5052
                     /locus_tag="ACL73E_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(5024..5800)
                     /gene="trpA"
                     /locus_tag="ACL73E_001669"
     CDS             complement(5024..5800)
                     /gene="trpA"
                     /locus_tag="ACL73E_001669"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGS0801606.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIKTEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDITLIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(5793..7016)
                     /gene="trpB"
                     /locus_tag="ACL73E_001670"
     CDS             complement(5793..7016)
                     /gene="trpB"
                     /locus_tag="ACL73E_001670"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGS0801607.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGREIPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(6994..7593)
                     /locus_tag="ACL73E_001671"
     CDS             complement(6994..7593)
                     /locus_tag="ACL73E_001671"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGS0801608.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKDGISGTK"
     gene            complement(7580..8347)
                     /gene="trpC"
                     /locus_tag="ACL73E_001672"
     CDS             complement(7580..8347)
                     /gene="trpC"
                     /locus_tag="ACL73E_001672"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGS0801609.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(8344..9348)
                     /gene="trpD"
                     /locus_tag="ACL73E_001673"
     CDS             complement(8344..9348)
                     /gene="trpD"
                     /locus_tag="ACL73E_001673"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGS0801610.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNLGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(9359..9925)
                     /locus_tag="ACL73E_001674"
     CDS             complement(9359..9925)
                     /locus_tag="ACL73E_001674"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGS0801611.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(9922..11283)
                     /gene="trpE"
                     /locus_tag="ACL73E_001675"
     CDS             complement(9922..11283)
                     /gene="trpE"
                     /locus_tag="ACL73E_001675"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGS0801612.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPVPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSDYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(12424..13425)
                     /locus_tag="ACL73E_001676"
     CDS             complement(12424..13425)
                     /locus_tag="ACL73E_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGS0801613.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         3898 a         3010 c         2307 g         4232 t
ORIGIN      
        1 ttatttatat tttacaacta taagaaagcc ttgtcaagga tttgtgtaaa tatttgatta
       61 ttttttatta tcaatatata ataaaaagag accagtaagc aatgaaaagc ttaaaaagat
      121 taacatctac atttatccat agcaaaaaat cataggattt taagaatctg acaactagga
      181 agaaaactaa tatgacctta tctaagaaac aattacaact aagagctaaa atactggaaa
      241 cagtttacac attaggtccc atttcacgaa ttgaaatcgc tactaaaaca ggaataacac
      301 ctgcaacaac tagcagtatc acaaatgatc tgattaaaga aaatattctc ttagaacttg
      361 gtgaagacga acacgataca agcgtaggga gaaaaaaaat cctgctagac attcaagcta
      421 aacgatttta ctacattggt tgtgaactat ctgaaaaaca tttcactttt gctttaggag
      481 ataatctagg aaatatctta aaggaagaga aagaaattgt tactaaacag ttaatccaag
      541 aaaagggaaa tcaactcatt aaccagacac taaagcaatt cttaaataac tgctctgatt
      601 atgaaataga agcaattgga atcgcgctac ctggtcgcta tttagatgat tataaaataa
      661 caacaaacaa tcctttatgg caacatatcg acttagaaat gattcaatcc cactttgata
      721 agcctttgtt tttctctaac aatgttaact gtatggctat aggtaaacgc ctatttagtc
      781 gccaacagaa tgaccctaat tttgcttatt ttcattttgc tagaggtatg cactgttctt
      841 atatctacga cggaaacatt tatgggaaag gaaatctaat gattggagaa atagggcata
      901 cagttgtttc atctgaggga gaagaatgta gctgcgggcg caagggatgc ttacaaactt
      961 ttgctggaga atcttggtta atcaaaaaat caaaaattct atatcatcaa tctccctatt
     1021 ctctacttcc tagtttagtc aaaaatgccg atgatattga tatccaagtt attttaaccg
     1081 cttatcaatt aggtgacact ggaataatca cacttatcca tcaagcctta ctctatctta
     1141 gtcaaaccat tttaaatatc agtatgatga ttgactctca aaaaatctac ctacatagtc
     1201 ctttactaac aaatcaacac atcatccaaa aactatatag tgaaatgaac tacaaaccca
     1261 aactgctcta taatcgccta cctgaagtca ttattgaacc ttacaatgat tttacagccg
     1321 cacactcagc tattgcactt tgtttgtatc atacaattct acattcttaa ttttctatta
     1381 catttaataa ataggctaaa aagagggagt atatcataaa aagcgaataa acctgttttc
     1441 tgaaaatcag aattctgttt tgttcgcttt ctttatattt ggaattatac tcctatctcc
     1501 cctttttcat aatgtatagt gaaatgaaat aataacagga cgaatcgatc gggacagtca
     1561 aatcgatttc taacaatgtt ttagaaatag aggtgtacta ttctagtttc aatccactat
     1621 attttcgtac aggtgcttca accatttgaa cgatttcaaa tccttctttt tggtaaagat
     1681 tctgagctct ttgatttgcc tcgaagacat ttagagaaat actatctata tcttcatttt
     1741 caaaggccaa actaacaaat ttccttaaag cctggctacc taagtcttgc tcctgtttct
     1801 gggggttgat aaaaaatctc ccgatatgaa gattgctgtc ttctagcctg attttctgga
     1861 taagtcccac aaactcttgt tcatcaaaga ttgaaaagac tccttccaag gcttgaaggg
     1921 gcagtagaaa aggaatcctt ggtcccatcc attgttcttg aaaggatttg cctagggagt
     1981 tggaccactg gcatacaaat tgagcgtttt ctatactcac cttttcttca aaacgaattg
     2041 tcatcttttc ctcaccatct tatctatgtt tctccattat actatttctc ccatttttta
     2101 cgaatagata agtatgattg atttttattt ttttctcgtc gggagcattc tagcttcctt
     2161 tcttggtttg gtcattgacc gttttccaga gcaatccatt atcagttcag ccagtcactg
     2221 cgattcctgt cagactccct tgcgtccctt agatttgatt ccgattctct cacaggtctt
     2281 caatcgcttt cgctgtcgct actgcaaagt tcgctatcct gtctggtatg ccctctttga
     2341 actaggctta ggactcctct ttctgcttta ctcttgggaa ttgctttcct tggggcaagt
     2401 cgtcctaatc accgctggtt tgaccttggg tatatacgac tttcaccatc aggaatatcc
     2461 cttactggtc tggatgactt tccacctaat cctaatagct tcctctggct ggaatctggt
     2521 catggtctcc ttcctcatac ttggaatttt ggctcatttt attgatatcc gcatgggtgc
     2581 aggggatttc ctctttttag cttcttgtgc tctcgtcttt agcgtaacgg agttactgat
     2641 cttgattcag ttcgcttctg cgacgggtat cctggccttt ctcctgcaaa agaaaaagga
     2701 aagacttcct ttcgtgcctt tcctcttact tgctacttgt ttgattattt ttggtaagct
     2761 actacttgtt tgataaattc caatttctgc catatgtact ccatgaaatt atttcacagt
     2821 taaattataa attatttctt ttgtacaaag ggatgatgtt atcaaatcga tctgttcttc
     2881 tatcttcttg atactgatca aaaaatttca tttcgactga aaatatttcg cttataaact
     2941 gtaaacgaat actttgttta gacattatag tcgctagact gactagatga ttactcaaaa
     3001 cgacgtccag aatactcttt actttgcttg gttttttaac aaaaatttga tcatccaaag
     3061 gttcaatcat tttgtaacct ttttgcgcaa tttgacgata aaagtaagaa tgttgctttg
     3121 gagtcaataa tcctaactta aaagctcgat actctaaagc ctgtatcgaa acattcaaat
     3181 ccgacttcaa taaaatataa ctatcaggat tgctgacacg cttgccaacc ctctcttcaa
     3241 atttgactaa aaactcttct tttggcaata aaaaacatga tgcaaaataa tttgcttctt
     3301 gctccaaacg atcgccatct tcattcatat ctttatattt atgtaaaaga atatgtccta
     3361 gctcatgagc taaatcaaaa tttcgacgta cagatgattt attcgttccc aacacaatat
     3421 aaggtcttcc caattttgac catgcgctat aagcatcagc ttggccatta attaatcgtt
     3481 ccacgatata gatgcctgaa cgttctaatt tataaagcaa atcatgatta tcttttgaaa
     3541 tacctaattt ttccctggca taaagagcca attcctcaat ggattctccc ttatgataag
     3601 attcactcac tacattactt aggtcatgaa ttgtaatatt aggtataatt acaaaacttt
     3661 caaaataatc aatcaaacta tctaccttat gtaaatacat agtttgaata tctattgttt
     3721 tccgggttgc taggtctgca tttctaaagg caattacaga agaatcaaat cgaatgctct
     3781 cttcttcctg ttcaaaataa gttaaatcaa catgaaattg gttggccaaa tgcattttgg
     3841 ttgataattt aggtttcgtt tcgttggact caaactgcca aatggcttgt tccgttaaat
     3901 taattctctg agctaattct gctctactta aaccatttaa cagccgtaat tctttcaata
     3961 cccgaccatt aaacatttac atactcctta ctacttttga ccttcttgtt tttctattct
     4021 tggaataatt tcaaaatctt ctgtttccga taattctgaa aaattaggaa tatcttgata
     4081 tttagcttct tcgaaatggt acgaacttga ttgaatatac tcagacaaat cttgaatcaa
     4141 gtgtaactga ccagttcgtg catcaggcat aacaacatct acagatataa tattgttttc
     4201 tgagtccgcc tcataagtta aaatcataaa tttttcgata ttcgaatttt tagtagcttg
     4261 ttcaatttct tgaatcattt catcagaaac taactccatc tgaattggaa aggaatgact
     4321 atcttcatca tttttgtagg aagaatgttg attaagataa agtgtattca tctgagcata
     4381 ttcaaataag tagccactct tatttttttg taccaaagga aattggttcg taagtcgctt
     4441 cttacccttt ataattaaca atactttccc atatttttct gtgtttgttt caaattctaa
     4501 atatccccaa gtctgtcctg ctaattgtaa tttatactca aacaaatctg ctgatgcaaa
     4561 tgcagtatca atatgattag gtcgcgtcca tgcataacca ttcgacacta tcattgtctc
     4621 tcttttttct agacgttcat ctacataatc tttttgccct ttcatcaaag tatctacaat
     4681 tttttgtgcc tcaagcgaat caaagagatc ctgattcaac ataattcttc ctcctccaaa
     4741 tactttttaa tgaattatat cattttctta aagaaattac tacaataatt agctttttct
     4801 taaagttctg tgtcagagta atttagaaaa ttatatcttc tatagtaaaa tcaattaaaa
     4861 actgaacaaa tttattggga aattcaaatc actttctaaa aatattttag gaaccgtagt
     4921 gtaatattcc agattcaatt tactataaaa ctagcctttc tcctgcaaaa gaaaaaggaa
     4981 agacttcctt tcgttccttt cctcttactt gctacttgtt tgattatttt tggtaagcta
     5041 ctgcttgttt gataaagtcc tgaatcggct ctccttggtg gagagctttt actattttcg
     5101 aaccgacgat aacaccatct gacaccgcat tgaagcgttc cagatcggct tgactagata
     5161 caccaaaacc tgtcaagact gggatgtcgg ccacttgatg aagttgcgcc aagtgcttgt
     5221 ccaaatctgc acggtaattg cctgatttcc ctgtcactcc attgatggca acggcataga
     5281 cgaatccctc cgccccttca atcaactctt tctggcgctc aattcctgtg gtcaagctta
     5341 ctaaaggaat caaggtgata tctgtatctg ccaaaaatgg ttctacaaag ttggcatgtt
     5401 catgaggcaa gtctgggata atcaagccct tcacagctgt atcagccaga tctttgacaa
     5461 agttctccac accgtactga aagagggggt tgaagtaggt catgatgacc agtggaatct
     5521 ctgttttaat ggttttcaag gtttcaacta aagcctgggt agaggtcccg tgggctaaac
     5581 tgcgcaagcc agcttcttcg ataacaggtc catctgcaac agggtctgaa aagggaatac
     5641 ccacttcaat tgcagagaca cccaaatctt ctaaaaagtg gattgtttct cctagtccat
     5701 ccaaaccttt ctcgtggtct ccagccatga tatagggaac aaaaattcct tttccagctg
     5761 cttttatagc atttaatttt tctgttagtg tcttaggcat gagcttctcc cttctttgct
     5821 gcatctgctt ccaagcggtc tttgacttga accacatcct tgtccccacg acctgatagg
     5881 catacaatca tagacttttc tggtccaagt tctttggcca atttcaccgc aaaagcgata
     5941 gcatggctag attccaaggc tgggataatc ccttccacac gagacaagag ttgaaatcct
     6001 tccaaagctt cttcgtctgt cacagggaca tagctggcac gtttgatatc gtggtagtga
     6061 gaatgctctg gaccgatacc aggatagtcc aaacctgctg agatagagaa ggcttcaaga
     6121 atttgaccat gggcatcttg gagcacatcc atgagagaac cgtgaagaac acccggacga
     6181 cccttggtca aggtagcagc gtggtgctct gtatccacac caagcccagc cgcttcagct
     6241 ccatacatgg ctactgactc atcttctaca aagggatgga agagcccaat agcattagat
     6301 ccaccaccaa cacaggctac tagggcatct ggcagatctc gacctgtcaa gtcacggtac
     6361 tgttgtttag cctctcgacc gatgacactt tggaagtcac gaacgatttc tggaaatgga
     6421 tgaggcccca aggcagaacc aaggatatag tgggtatcgt cgatattagc cacccatgaa
     6481 cgaagggctg cattgaccgc atccttgagc acgcgcgaac catctgtcac ggcctcgacc
     6541 ttagctccca aaagctccat acggaagaca ttgagggctt ggcgtttgac atcttcctca
     6601 cccatgtaga tggtacattc catgttaaag agggccgcag cagttgcagt tgccacaccg
     6661 tgctgaccag cacccgtttc tgcgataatt ttctttttac ccatgcgttt ggcaagccaa
     6721 acttgtccta aggcattgtt aatcttgtgg gctcctgtat ggttaaggtc ttcccgtttg
     6781 agataaatct tggctccgcc gatatgctgg gtcaaatttt ttgcgtagta aaggggaatt
     6841 tcacgtccca catactggcg caaaagttgg tttaattcct cttggaaact tgggtctgcc
     6901 tgactttcac ggtaggcctt ctccaactcc aaaactgctg tcatcaatgt ttctgggaca
     6961 aaacgtccgc cgaattttcc gtaaaatcca tctttatttg gttcctgata tgccatcctt
     7021 taccctctct ataaatcttc taatcttttc atgatctttt tgtccatctg tctccactcc
     7081 actcgataca tctactgcat agggagtaaa atgttgaatt gcttttacta cattatcttc
     7141 attaaggcca cctgcgataa agaagggctg tgctagtcca gtcgtatcca gttgacccca
     7201 atcaaaggac tggccacttc ctgccacagg ggcatcaaag agtagataat ctgcctgaga
     7261 attggggaca tgcccatttc catctacctg cacagcctga atactggcac aaggcaaatt
     7321 ctcaaataaa tcatctgcca cctgaccgtg aacttgaacc aagtccaagc caactttgtc
     7381 aatcgcttcc agcagttcta cccgacttgg tgaaacaaat actccaacct ttttcacatc
     7441 tgcaggaata agctttgcca actcagctgc ctcttctaaa gtcacctgtc ttttactagg
     7501 tgcaaagaca aaaccgatat agtcggctcc tgctgaaacg gctgtttcca ccgcttcttt
     7561 ggtcgatagt ccacaaattt taacctttgt caatctgcaa ctccttgatt ctctgggcca
     7621 cattttctgc ctgcataaga gctgtcccta ccaaaattcc gttaaagtat ggggctagtc
     7681 gttccgcatc ctgccctgtg aaaatggcag attcagaaat gtaatagcga ccttcctcaa
     7741 agtaaggggc taaatctaca ctggtctgca agtcgacctc aaaggtagtc aagttgcggt
     7801 tgttgacccc gataatctca gcaccaagtc tgtgggctac ctctagttca gctagattgt
     7861 gagtctccac taagacttcc agaccaagct ctgtcgcgta gtcatacagt tccttgaggc
     7921 gttcttcgga caaggctgcc acaataagca agataactgt cgcacctgca ttgcgagcgc
     7981 ggatgatttg cttttcatct atgataaagt ctttgttgag cgtcggaatc tctacctgac
     8041 tggaaatttc ccgtagataa tccaaatgcc ctttaaagaa aacctcatct gtcaacaccg
     8101 aaatcatcac tgctccgttt tcttcataag tctgggcctg ttgcacaata tccacatcga
     8161 gattgatatc tcccaaacta gggctagctt tcttgacctc agcgattacc tgcaagcggt
     8221 cctgatgatt cttcaaaaat tctgccaagc gataggtctg gcgcagaggc tggatttgct
     8281 ccagcttcat ctgctccacc tcacgcgcct tctgctctaa gattcgtgct aaaaattcct
     8341 gactcatttt tggtactcct gtaacagtct gagtttttca agggccttgc ctctagcaat
     8401 cacttgacgg gccaaggcaa ctccttcctt gatgctatca atcttaccat tagcatagaa
     8461 accaagacca gcattcaaga ctgtcgtttc caagaatgga cttgcttcgt ttttcagaac
     8521 gctaagcaaa atttctgcat tttcctgagc attcccacca cgaatatctt ccatagcata
     8581 gccttccatt cccaaatcct ctggagtaaa gcttgacaag ctgatttcgc cattttcaag
     8641 aagtgcaatc ttggttgttc cgttcaagcc agcttcatcc aacccttctg gtccagcaac
     8701 cacgatggca cgtttgcgac ccagattttt caaaacctga gctgtacttt ctaggagttc
     8761 tggacgacta attccaagaa gctgtgtttc taaagccatt ggatgaatca gtggaccagt
     8821 caagttcata atcgttggaa ttcccaattc caaacgagct ggcatgatgt atttcatagc
     8881 tgggtgcata tttttagcga agagaaagac gattccagtt ttatcaaaga ccttacctag
     8941 ttcagctggt ttgagatcaa gattgattcc caaggcttcg aggacatctg cggaaccaga
     9001 tttagaagaa atcgagcggt taccatgctt ggccatgtga ataccgccac cagccaagac
     9061 aaaggctgca gttgtggaaa tattaaaact gaaagacttg tccccacctg taccacagtt
     9121 atccatggca tcatgaatct cagttggaat atgctgggca tgtcctctca tgacttgggc
     9181 aatggctgtg cgttcttcag gtgtttcccc cttcatctta agagctaaga ggagagaagc
     9241 aatctgcgct tcagttacac gcccagttac gatacgctca atgacatccg tcatttccac
     9301 acctgataaa ttttcaaatt ttgctagttt ttcaataatc tctttcatcc tagtttcctc
     9361 actttacaac ctcctcgata aaattccgaa tagaagacaa gccgtctggc gttccaatgc
     9421 tctctggatg gtactggaag ccataaatcg gtaggttttt atgttgaatc cccatgatgg
     9481 cttggtcatc agtcgaacga gctgtcactt caaagtcttc tggcatttcc tcaatcaaaa
     9541 tactgtgata acgcatgacc gcacggccat cctcaatacc ttgatacaaa acagatggcg
     9601 cttcaaagtt gatattgctc tgtttcccat gcatgacttt tggagccaaa cctagcttac
     9661 caccaaagac ttctgcaatg gcttggtggc ccaaacaaat ccctagaatc ggcttcttgc
     9721 ctgcaaaatc acgaatcatg tcttccatct ttccagcatc aactggccaa ccaggaccag
     9781 gagaaaagac cagaccatct gctttttcag cttcttcata cagcttggaa tcatcatttc
     9841 tcaaaacctg aacttctgca aaattcccaa tgtattgggc caagttatag gtaaaagaat
     9901 catagttgtc aatcaataaa atcatggtct tagttctcca attctagtca tagattttgc
     9961 tttgttaatg gtttcttggt attcgttttg ggcgatagag tcgtagacaa tccctgcccc
    10021 agcctgcaca taggctcttt gatttttgag aatcatggtt cggatggcaa tggccaaatc
    10081 catatcaccc gtcgcagaca agtagccgat tgctcctgca tatacgcccc gtttttccgt
    10141 ttccagttca tagatgcgtc tcatcgctcg aatttttggt gctccagaaa cggttccagc
    10201 aggaagcgtt gctttcaagg catccatagc agtgagttct gcaagcaaac gccccttgac
    10261 cacactggtc aaatgcatga cgtagcggaa gagctccacc ttcatatact tagtaacttg
    10321 gacactggcc gtttcagaga tgcggccaat atcgttacgc cccaagtcta ccaacattcg
    10381 atgttctgct gtttccttct catcagagag gaggtcagtc gccaaggtct tgtcttcttc
    10441 atccgtagcc cctcttggtc gcgtccctgc aatcggattg gttgtcacga tgccattttt
    10501 gacagaaacc aaactttctg gactagctcc gatgatttga taatccccaa aatcatagaa
    10561 ataaaggtaa tcagaaggat tagtcacgcg gagatttctg tagaagtcaa atggatttcc
    10621 agtaacttct gctgagaaac gctggctgag tacacattgg aacatatctc cgttacgaat
    10681 caagtcacga gctgtttcta ccattccctc aaacttatgt ggagcgatat gcggtttgaa
    10741 gtctaacgga gatagatcca agtcttcaaa ttcatttgga acaggaatgc gtaattcctc
    10801 aagcacttgg ttcaatgatt tttccaaggc ctcttgactg cgctcactat aaagtgcatc
    10861 ctctatgaca tgtatcttct ccttcttgtg gtcaaagacc atatagctct catagacaaa
    10921 gaaatgcatg tctggcgtcc caattgtatc ctcagggatt tgaccaattt cttcataaag
    10981 cgaaatcata tcgtaaccca caaaaccaat ggctccacca ccaaaaggga gctctgagtg
    11041 gtgctgactc ttatgaatca cttcataaag gaaatccaag ggatcccgat caatcacttg
    11101 accattttga tagagaactc cattttcaaa cttaatctca aaaactggat tataggctag
    11161 gatagaaaaa cgagccgttt ccttgtctct cggaatactc tctaaaataa ccttatgttg
    11221 cccctttaag cgcatataag ccaagattgg tgataagaca tctccatgaa tgattcgttc
    11281 cattgtaatt tccctttcag ttctaattct agttcgtggc gactgtatga aaaatcccca
    11341 cgcaaaataa cttgcgtgag gacgaaattc gcggtgccac ctcaattata ggatttctcc
    11401 tatctctcat tcctgtctca gatacctcct gtaacaggct gtgcgataaa gggcactccc
    11461 ttgagaatga tgttttcttc tctcgtttca gatgaaccca actttacagc tttctctgct
    11521 tgttttcagc aaccacaagc tctctgtgag agaaaagact gtaatttttc catctattat
    11581 tttttagctt ctagtaatct gcaatcgcag ctaggtcctt gcctccacga ccagagacat
    11641 tgatgaagag atgttcatct cggtacacct ttatactctt cgaaaatctc ttcaaaccgc
    11701 gtcaacgtcg ccttgccgta ggtatggtta ctgacttcgt cagttctatc cacaacctca
    11761 aaacagtgtt ttgagcagcc tgcggctagt ttcctagttt gctctttgat tttcattgag
    11821 tattactagc ttttttcgta ttagtccagc ctttttgttt gcttttagta gtaggcaagg
    11881 agctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa agataaacca
    11941 aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg cgttggtaac
    12001 gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg tttaacaaca
    12061 agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt ttcaaaatca
    12121 gcccactttc actacttcca accacctatt cacaatcacc acaggctccc tgaagatcaa
    12181 aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt ctttgtcaag
    12241 acttttttac gatttttttg aaaatatcat tcgaatgtga ccatgtcttc cttagatcga
    12301 acatgaacat gtcccacttg ttagaaattg gatccaactc aatagaaact gaatggaggc
    12361 taaacagaac ttattttaga acactccatc ttttccacta ggattttcaa gaattaaaca
    12421 atactagaaa ctctgtctcc taacaaattt aggagaaact tcaacagatg tgacactttc
    12481 ccctttaata attgctaaaa caccttctat catttcttta gccaatttaa cataattggg
    12541 agcaattgta gacaaagctg gagtataata ctgagaaata ggaatattat caaatccaat
    12601 gatagaaata tcatctggaa taagaattcc tttctcatag cacgcacgaa tcaagccctg
    12661 aaccttttca tctcctgaaa caaaaataat gtccggataa ttttgggtag tcaagtgctg
    12721 cattgcataa gaataaactg aatcaattgt agataagcca taaatgactt ttaaatccat
    12781 aaagtaattt ttatcattca gaaaagaacg cacacctctt tcacgatcct tattaacatg
    12841 ggattctcct cccataagca accacatatt tttaaatttt tcttcagtta cagctttcat
    12901 catatcataa gtagcttgaa aattattatt agatacatag actactccag acgtttgaga
    12961 ttcaccgaaa acaagaaaag gcatatggtt cttctttaaa tactgaattc tgatatcatc
    13021 tacactttca taaaaaacaa taacaccatc tactaggcta cctgtgcttg atataattga
    13081 attactaatt gtatcctcct ctccaaagta ctcaactata gcattaacac caaattcttt
    13141 acacgtccgt aacactttat ctaacagcgt atgaaaccaa attaaaggaa aagagtcgat
    13201 tttttttaca gaaatcaata tatttatagc ttctttttta gttaaatttt ttgcatacgc
    13261 atttggaata tacgacaatt cctctataac tttttgaatc gcttgataag tttcttcttt
    13321 aacatttact ccaccattaa taactcgtga aactgttttt ggagaaaaac ctgataaacg
    13381 tgcaatatca taaatagtta cctttttccc atttatattt ttcatttcag tcctccatta
    13441 cgaacat
//
LOCUS       DBERDS010000048        13060 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.048, whole genome shotgun sequence.
ACCESSION   DBERDS010000048 DBERDS010000000
VERSION     DBERDS010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.048"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..1000
                     /locus_tag="ACL73E_001677"
                     /pseudo
     CDS             1..1000
                     /locus_tag="ACL73E_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1085..2287)
                     /gene="rpsA"
                     /locus_tag="ACL73E_001678"
     CDS             complement(1085..2287)
                     /gene="rpsA"
                     /locus_tag="ACL73E_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGS0801614.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2449..2520)
                     /locus_tag="ACL73E_001679"
     tRNA            complement(2449..2520)
                     /locus_tag="ACL73E_001679"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2486..2488),aa:Gln,seq:ttg)
     gene            complement(2530..2610)
                     /locus_tag="ACL73E_001680"
     tRNA            complement(2530..2610)
                     /locus_tag="ACL73E_001680"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2574..2576),aa:Tyr,seq:gta)
     gene            complement(2660..2890)
                     /locus_tag="ACL73E_001681"
     CDS             complement(2660..2890)
                     /locus_tag="ACL73E_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGS0801615.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3058..3702)
                     /gene="pcp"
                     /locus_tag="ACL73E_001682"
     CDS             complement(3058..3702)
                     /gene="pcp"
                     /locus_tag="ACL73E_001682"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGS0801616.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3717..4640)
                     /locus_tag="ACL73E_001683"
     CDS             complement(3717..4640)
                     /locus_tag="ACL73E_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGS0801617.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4637..5326)
                     /locus_tag="ACL73E_001684"
     CDS             complement(4637..5326)
                     /locus_tag="ACL73E_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGS0801618.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5391..6095)
                     /locus_tag="ACL73E_001685"
     CDS             complement(5391..6095)
                     /locus_tag="ACL73E_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGS0801619.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(6151..7173)
                     /locus_tag="ACL73E_001686"
     CDS             complement(6151..7173)
                     /locus_tag="ACL73E_001686"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGS0801620.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7305..9776)
                     /gene="parC"
                     /locus_tag="ACL73E_001687"
     CDS             complement(7305..9776)
                     /gene="parC"
                     /locus_tag="ACL73E_001687"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGS0801621.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9977..10181)
                     /locus_tag="ACL73E_001688"
                     /pseudo
     CDS             complement(9977..10181)
                     /locus_tag="ACL73E_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(10196..12139)
                     /gene="parE"
                     /locus_tag="ACL73E_001689"
     CDS             complement(10196..12139)
                     /gene="parE"
                     /locus_tag="ACL73E_001689"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGS0801622.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12275..12916
                     /gene="plsY"
                     /locus_tag="ACL73E_001690"
     CDS             12275..12916
                     /gene="plsY"
                     /locus_tag="ACL73E_001690"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGS0801623.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12959..>13060)
                     /locus_tag="ACL73E_001691"
     CDS             complement(12959..>13060)
                     /locus_tag="ACL73E_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS0801624.1"
                     /translation="QAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         3770 a         2952 c         2299 g         4039 t
ORIGIN      
        1 attgctcaaa agttaattga aaagatttct atgactgata ttgcccatca gctttccatc
       61 tcaacttcaa ctgtcattcg caagctcaat gattctcact ttgagcatga tttttcgcgt
      121 cttcctgaga ttatgtcctg ggacgttgaa acagtccggg gagtgactgt ttcaatcggg
      181 agatggagat gagcttcatt gcgcaagatt ttaacaatct caatatcatc actgttcttg
      241 agggaagaac acaagctatc attcgaaatc actttcttcg ctacgataga gctgtccgat
      301 gtcgcgtcaa aattattact atggatatgt ttagccctta ctatgacttg gctaaacagc
      361 ttcgctttca aatttctagg ctcaggctga aacagtctcc cagactgttt cactcccgaa
      421 tgctaaaatc gttcttgatc gctttcacat tgtgcaacat cttagccgtg ctatgagtcg
      481 tgtgcgtgtt caaaacatga atcagtttca tcgaaaatcc catgaataca aggctatcaa
      541 gcgctactgg aagctcatac aacaggatag ccgtaaactg agtgataagc gattttatcg
      601 tcctactttt cgtatgcatt taaccaataa agagatttta gacaagcttt tgagctattc
      661 acaagacttg aaacaccact atcagctcta tcagctcttg ctgtttcact tccagaataa
      721 ggaaccagag aaatttttcg gacttattga ggacaatctt aagcagtctc atcctatttt
      781 tcagactgtc tttaaaacct tcctcaaaga taaagaaaag attatcaacg cccttcaact
      841 acactattct aatgccaaac tggaagcgac caataatctc atcaaactta tcaagcgcaa
      901 tgcctttggt tttcgaaact ttgaaaactt caaaaaacgg atttttatcg ctttgaacat
      961 caaaaaagaa aggacgaaat ttgtcctttc tcaagcttag ctgacttcaa cccactacag
     1021 ttgacaaaga gccagaaaaa tcccttgttt agtaaacaaa ggattttgtg aattttcaat
     1081 ttgattaaag ttcgatatca ccaaacaaat cagccattga aaatcctgtt tgtgtttctg
     1141 gaagttcgaa atcacgcttt tcttgacgtc ttggacgacg tggacgagca gcacgttttt
     1201 cttctttttg tccttcttct tgggctggac gttcttcaag agctttaata gaaagtgaca
     1261 cgcgttctgc atctgcgtta acttcaagaa ctttaacttg aacttcttga ccaactttaa
     1321 gagcttcttt tggattttca atccgtttgt gtgaaatttg tgatacgtga acaagtccat
     1381 cgatacctgg caatacttca acaaatgcac cgaagtcagt caaacgttta actgttcctt
     1441 ctactacatc acctttagcc aatttttgct caacgccatc ccatggtcct ggtactgttg
     1501 ctttaagtga aagtgataca cgtccttctt cttcgttaag atcaaggatt ttcacttcaa
     1561 tttcttcacc aacagttaca actgattttg gtgatacgtt acgttcatgt gacaattcag
     1621 tcaagtgaac caatccgtca acaccaccaa ggtcgatgaa agcgccgaag cttgtgatac
     1681 gagcaacttt accagttaca acatcaccaa cagccaattt accgaatact tcagcgcgag
     1741 ctgctgcagt agctgcttca acaacttcac gacgtgaaag gatgaagcgg ttttctttag
     1801 cgttaacttc tttgatttta gtatcaaatt cttgacctac aaaacgctca gcgttacgta
     1861 cgaaacgagt atccaacatt gaagctggga taaatccacg aacaccttca aattctactg
     1921 aaagtccacc tttaacggca cgcgttcctt taacagtaac aacttcttct tcgcgaccaa
     1981 caagtttgtc ccatgctttg cgagcttcaa ggcgtttttt agatacaagg tatgtaactg
     2041 tatcagtatc tttaccaact acttgacgaa gtacaagaac atccaatact tctcctactt
     2101 taacaaagtc attgatatct gcatcacgat cgtttgtcaa ttcgcgaaga gtcaagacac
     2161 cttcaacacc agttccagag attgcaacgt tagcttgagt cgcatcaact gtcaatactt
     2221 cagcactaac aacatcacca gtctcaactt gactaacgct atttagcaaa tcttcaaatt
     2281 cgttcatcta aaaaatcctc caacaatcaa gtttttctta aacttgacat acttataatt
     2341 tttttcctaa gcacccgcaa ggacatgttc atatcattca cgtctttcaa ttataaaaat
     2401 aaaataccct aagatatttt gctttctatc ttgattatta cctaagaact ggggtagctg
     2461 gattcgaacc aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca
     2521 ttaatgaaat ggagagagag ggattcgaac ccccgaaccc gaaggagcgg atttacagtc
     2581 cgccgcgttt agcctcttcg ctatctctcc tacaatcaac atggactatt atatcatgaa
     2641 aatttcaaaa aaacaagact tattttgcta aattataatt ttcaatcaaa atttccacag
     2701 ctttttccaa ttttttataa aaactatcga cattcccatt ctttataatg gcaaattgtc
     2761 cgtctaattc ggcaatttct ccgataactt ttttaccgat agtcaatgta taaccttcaa
     2821 aactgtcttt accaacatta actttggcat ccgctacttg aatttcgatt tttttatctt
     2881 tcttgctcat ttcatacctc tcttcacttt ttctatttta caagaaaatc ctaaaactag
     2941 caagaaaaaa ctctatatca ggcttctctg atatagagtt ttatgtaaac aacctcaatt
     3001 gatttagcat agttaatagt tagtaaacaa gcataattga ctatcctttt taggttatca
     3061 gtgagtctca ccgcctacta actgcaaatc cttatctttg tagtctacaa tagcttcaat
     3121 agctacctct atgcctctta caatatcaca tagactcatt cctgcagtat tcggcttatt
     3181 tactacttgt tccatcatat atggaatatg catgaaacct gctctcatat tagggaattt
     3241 tttatccact aaataaagag cttggtacat caaatgattg caaacaaagg ttcctgcact
     3301 attggataca actgccggaa gtccctgttt tttgatagct tgtaccatcg ctttgatagg
     3361 taaactacta aaataggccg atgctccatc aatacgaatc ggtgtatcaa ttggttgatt
     3421 gccttcgtta tcaggtatgc gagcatcatc ttgattaata gccactcgtt caggtgttaa
     3481 gccggtcctg ccgcctgctt gtccaataca aagtacagca tctggttgat atcgtaatat
     3541 ttctgcctct aaaacttctg acgacttata aaaaaccgtt ggaatttcta cccagcgaac
     3601 ttcagcccca ttaatctcag atggtaataa ttttacagcc tccaaagctg gattaatctt
     3661 ttcacctcca aaaggattaa aacctgtaac caatattttc attttatttt cctttactaa
     3721 aatgcgagaa agtacattaa gaatatgtga ataacaatca ttactagagc aacacctgct
     3781 tgagccttta taacgccatt ctgatctttc atatccatca atgctgctgg tagagcgtta
     3841 aaattagcag ccattggggt caataaggtc ccacaataac ctgctgtcat ggcaagagca
     3901 ccagccacaa ttggattagc tcccagagca aatacaaagg gaactccaac acctgctgta
     3961 ataacggtga atgctgcaaa agcatttccc ataatcattg tgaatagaac cattccaaga
     4021 acataagcca aaactcctat aaagcgacta tctgaaggaa caataccgct aatcagatga
     4081 gagataacat caccaacacc tgctacagta aaaatagccc ccaaagcccc taataattga
     4141 ggaacaatcc cacttgttga aacttgctga gtcattcgat tattttctga taacagactc
     4201 ttagggtgac tattggtaat cacaagaaca gaaattgtag caaacaaggc ggcaaggcta
     4261 atcgaaatct tgctaaattc tggaatcatt tgcgctaaga ccaacgcaag tattgccatc
     4321 agcataactg gaataaaaat tttatttttc aacctgttag attcaatatt ggctttcatt
     4381 tcatctaagg atggcaaggt tccgatacgg acttgcttaa acaatgttaa cagcgataat
     4441 aggattacaa taataccaat actcatattt ggcatatagg aaccacctat aaacgtaata
     4501 gacaatagag tccaaaatgc agatgtccca agtcgaactg ggtttgtttt atctttataa
     4561 ctacaatagg ctgtatggag aaattgacaa ccaatcacaa tataggtcaa ctctaatagt
     4621 tgctttgcca actctgtcat ttttgttctc ctcccctagt cttttttgat atcaattttt
     4681 tatcaaataa ataattgtaa atccccacta caataagtgt tataacagca acaataatag
     4741 atgtagaagc aatccctgca taattgcttt catagcctaa ctgatctaat gttcccccta
     4801 tcaagaggac tcccccagca cctacaaacg tattttgagc aaagaaattt ccaaaatttt
     4861 cattcgcagc cgcacgcgct tttattgtct catcttcaac ctctgttaac tttctaccta
     4921 attgagactc tgcagctgct tctcccatag gttgaaccaa aggtctgaca aactgagggt
     4981 gtcctcctag acgaattgaa aagaaaccag ctaactctcg aataaagaaa taaactgtat
     5041 agaagtttcc aactgtcaga cctttaatct ttcgaatcaa atcgattgat cgttgcttga
     5101 gtccaaaggt ttctgacagc cccacaagag gcaaggtaac cataaaaatc gtgagcactc
     5161 gctgattgct aaattctttt cccaaaatct ccaaaaattc aacgagagaa acacctgaaa
     5221 ctaaagctgt aaccaaacca gctaagacta ctgttgcaat tgtatcaaat tttaaaataa
     5281 aacccacaac aatgattgct attcctatta atctaatcca ctccatatca aactccttta
     5341 tattcaaaat gacagtattt taaaaatttt atcaagatca ataccattcc ttatttaatg
     5401 tatttttcta gttctttttg gtatttgcta ttggattcca atttttcttt ttgccatttt
     5461 ttaaaaacct cgttatattc ttttgttgta acaatatctt tttgcaattt cattccttta
     5521 aagatatatg gttccccctt aataccaact tgtgagtatg gttttgagaa tggtactacg
     5581 ttacttacaa ctggagaacc accagatgaa gctgttggca tcaataatga actatctgtc
     5641 gaccaagctt gagctttggc atatttttca tatctcttct ctaggtcagt ggtctcagaa
     5701 acagcatctt ctaacaattt cttatattta tccaaaccag gtttagctac aacatcctta
     5761 tcttttcctt tcgtaatgcc aaggtgtttc atggcagaac cagattttgg atccataata
     5821 ttcaagtaag acgctggatc ttgatagctt ggagcccatc ctgtactatt caaatcatag
     5881 tctttttgag aaggagcaac attgccgtat ttatcatttt ccatcaaacc atcaataaca
     5941 tttccaataa cgtctgtcgt cgatgttcga gtcgctatac tgtagcccaa tgatgctgga
     6001 tctactgcat agacataaga aaatgttgtc ggtgcatctg cttctttatc agtttttcca
     6061 caagccacta aaatagctga cgtgctcagg accactcctg ctgttaagag ccgctttttc
     6121 tatttcataa aaaatctcct ttggtttatt ttaatctact tttacaatcc aaccttctgg
     6181 cgcttcaata tcgccaaact gaatacccgt caattcatta tataatttac gcgtcacagg
     6241 acctacttct gtttcactat agaatacatg gaaatcatca ccatgttgaa tacctccaat
     6301 tggagaaata accgctgctg taccacaggc acctgcctct acaaaacggt caagattatc
     6361 aattggaaca tcaccctcaa taggagttaa tcccaagcga tgttctgcca aataaagcaa
     6421 ggaatacttg gtaatagatg gcaagataga tggactcaat ggtgttacaa attcattatc
     6481 agctgtaatt ccaaagaagt tagctgatcc gacttcttca atctttgtat gagttgatgg
     6541 gtccagatag ataacatctg agaaatgacg tgacttggcc atttttcctg gtaagagact
     6601 tgcagcatag tttccaccaa ccttagccgc acctgtacca tttggtgctg cacggtcgta
     6661 ctcatcctga atcaagaagt tggttgggac caaaccacct ttaaagtaat ttccaactgg
     6721 catagcaaag atggtgaaaa tgtattcttc tgccggtttt accccgataa tatctccgac
     6781 accaatcaaa agagggcgaa gatataaggt tccacctatt ccgtatggtg gtacgtattc
     6841 ttcattcgca cggacaactg ctttacaagc ttctacaaac atgtctgtcg gaacttgtgg
     6901 catcaagaga cggtcacatg tacgttgcag gcgtttagca ttttcatcag gacggaacag
     6961 ttgaacactg ccatccttag tacgataagc tttcaaacct tcaaatgctt gttgtccata
     7021 gtgaagactt ggagaagact ctgaaatatg caaagttgca tcctctgtaa gctctccttg
     7081 atcccattgt ccatttttga aatgagcaag atagcgataa ggtaatttca tataggaaaa
     7141 accgaggttt tcccaatcaa tcgttactgt catattccac tccttattct aaaaacctat
     7201 ttcttatatt ctacactatt tttctaaaat agcaagtata ttttgtaatt ttcagaaaat
     7261 ttctccaata aaaaccagct cttagaactg attcttcatt tcacttattt atcttcagta
     7321 actacttcct gaagataagc gtcaaaaact tcttcatctg aaatcgtgtc agaaatgaag
     7381 cttccattgc tagtgcgttc tgacaagttc aagtcttgca atcggctttc atagattgtt
     7441 cctttattgg attggacaag cagagtttgg tcgttcacat ccacttccgt actgaagaaa
     7501 tcgccaacaa atccttgctc tgcaactgct cctgccaaga agacacgatg cggtttgttt
     7561 ttcaactcac gcaagacttg taatcctcgt ttggcacggc tggttgctag aatttcctca
     7621 atggaaacac gtttcaagct tccacgctgg gtcaagaggt agaaggacga agtattacag
     7681 ataaagccag attggaggac atcatcttct ttcaaattca tagccttgac acctgctgcc
     7741 ttagcaccga caaccggaac ctcttcgata ttgaaacgca gggcataacc attttgacta
     7801 accaagacaa catcatctag tttaatcgga gccactgcta caatctgatc tgtatcgtct
     7861 ttgagcttag catacttgac agacttagat ctataggtcc gccatggagt gaattctttt
     7921 cgctctaccc gtttgatttg accaaggcga gtcgctgcaa agtaggttgt cgcatcgtca
     7981 aactgatcca gtacttccac ataaaggatt gcttcattcg tttcaaagtt tgtgatggtt
     8041 tggctcagat gctctccgat gtccttccaa cgaatatctg ccaactcatg gattggtctg
     8101 tagatgacat ttccaagact tgtgaacatc aagaggtgct gggttgtctt ggcagattga
     8161 acaaaaatca aacggtcatc atcacgcttg ccaatttctt ccaaggtgga agccgcaaag
     8221 gaacgtggac tggtacgctt gatgtaacct gccttggtca cgctgacgta ggtatcttcc
     8281 tcagcgataa gactagctgt atcaatctca attgctttcg cagtgtcttc taaagaactc
     8341 aaacgaggag ttgcaaattt cttcttgacc tcacgaagtt ctttcttcat gagattgtac
     8401 atagtccttt catcaccgat aatagccacc agcatagcaa tcttctcacg aagctctgct
     8461 tcttcttcct gcaagacaac cacatcggta ttggtcaaac ggtacagttg caaagttacg
     8521 atagcctcag cctgttcttc cgtaaaatca tagctaactt tgaggttttc cttggcgtcc
     8581 gccttattct cagaagcacg gataagagca atgacttcat ccaaaatcga aatcacacga
     8641 atcaaacctt cgacgatatg gagacgtttc tcagcctttt ctttgtcaaa gcgtgaacgc
     8701 gccaaaatca cttctcgacg gtgagcgatg tagctagaca ggattggaac aatcccaacc
     8761 tgacgaggtg tgaaattgtc aatcgccacc atattaaagt tgtagttgat ttgtaggtcg
     8821 gtgtacttaa ataagtagtt gagaacaagc tcagtattag cgtctttctt aagttcgata
     8881 gcgatacgaa gaccatcacg gtcagactca tcacgaacct cagcaatccc agctaccttg
     8941 ttattaacac gaacatcatc gattttcttg actagattgg ccttattgat ttcataagga
     9001 atctcagtaa taacgatttg ttccttacca ccttttagct tttcaatttc agtcttggaa
     9061 cgaacaacca cgcgcccttt cccagtctca taagctttct tgatttcatc acgaccctga
     9121 ataatagccc ctgtagggaa gtctggtcca ggcaagaatt ccatgagttt atcaatcttt
     9181 gcagttgggt ggtcaatcat gtaaactgca gcatctatga cctcagctaa attatgggga
     9241 ggaatgtctg tggcataacc agccgaaatc ccagtcgaac cattgaccaa gaggtttgga
     9301 aaggctgctg gcaagaccgt tggttctttc tccgtatcgt caaagttcca tgcaaaagga
     9361 actgtctttt tctcgatatc ctgaagaagg tagcctgcaa tttcagacaa acgtgcctca
     9421 gtataacgca tagccgcagg aggatctccg tccatagaac cgttattacc gtgcatttca
     9481 actagaatct cacgattttt ccagttctgt gacatacgaa ccatggcgtc atagatagaa
     9541 gaatccccgt gtgggtggaa attccccatg atgttcccga ctgacttggc cgacttacgg
     9601 tagctcttgt caaaagtatt gctatcctta ttcatagaat aaagaatacg gcgctgaacc
     9661 ggcttcaacc catcacgaat atctggcaaa gcccggtctt gaataatgta cttggagtag
     9721 cgaccaaagc gctctcccat gatgtcctcc agggacatgt tttgaatgtt agacataaga
     9781 tacaaagccc ataaaatacc aagtgaaaat agaaaattct tgaagtaagc aaactcacaa
     9841 gagaatttat ctttttcaca cagtatctag ggcgtgttca actcctttca aagaatgtag
     9901 agtaggtttt tatgcagtaa aagatatttt acgggaattc gtcccgtgtt cagttacgat
     9961 aagtaaccaa actatcctgt ttgtattttt caatatgaaa atatggtttt ccaaaattag
    10021 tcttagtttg tgtcttagcc gctcccttaa acgcctcttt gagataagca ctcatagcag
    10081 attcttcatt aataatcctg caattttttc aaaccaagat tttcaaactg ctttttcaca
    10141 tagtcattca catccgactc taatttccag tttactaaca tattattttc tttcattaaa
    10201 acactgtcgc ttcttctagc gtaaacttga cattatcttc aatccattta cggcgtggtt
    10261 ctaccttatc tcccatgaga acattgacgc ggcgttcggc gcgcgctaaa tcttcaattg
    10321 tgacacggat gagggtacgt gtttctgggt tcatggttgt ttcccagagc tggtccgcat
    10381 tcatctcacc aagtcctttg tatcgttgga gggtagcgcc tttaccgaac tgtttacgga
    10441 gttcttctag ttctccgtcc gtccaagcgt aggccacttc ttctttcttg cctttacctt
    10501 tggacatctt gtaaagaggt gggagggcaa tatagacatg acctgcctcg actagcggac
    10561 gcatgtaacg gtagaaaaat gtcaagagca aggtctggat atgggcaccg tcggtatccg
    10621 catcggtcat gataatgatc ttatcatagt tggcatcttc aatagagaag tctgctccaa
    10681 cacctgcacc aatggtataa atcatggtat tgatctcttc atttttgagg atatccgcca
    10741 tcttggcctt ggctgtattg acaaccttac cacgaagagg tagaatagcc tggaacttgc
    10801 ggtcacgacc ttgtttggca gaaccaccgg cagagtcccc ctcaactaga tagagttcat
    10861 tcttagcagg attcttagat tgggctgggg tcaatttccc agacaacaag cccttatctt
    10921 tcttgttttt cttcccattt cggctctcat cacgcgcctt acgtgctgct tcacgagcat
    10981 cacgggcctt gatagccttg cggatgaggt tagaagctaa ttccccattt tccataagga
    11041 aaaaggtcaa cttatcagcc actattccat ccacaactgg gcgagctagg gggcttccta
    11101 gtttatcctt ggtctgtcct tcaaactgca agtgttcttc aggaactaag atagaaagaa
    11161 cggccgctag tccctcacga tagtctgaac cttcaaggtt tttatctttt tccttgagaa
    11221 gacctgtttt acgtgcatag tcattcatga ccttggtaat ggcagacttg agtcctgtct
    11281 cgtgcgttcc accgtccttg gtgcgaacgt tattgacaaa ggatagaatg ttatctgaga
    11341 atccgtcatt gtactggagg gctacttcca cttgaaaacc attgtcttcc ccttcaaagt
    11401 aaagaactgg cgtcaagatt tccttatctt cgttgagata agaaacaaaa tcttgtactc
    11461 cattctcata gtggaactca atcgcttcat ctgttcgctt gtccgttaaa gacaaggtca
    11521 catttttcaa gagaaaggct gattcattaa ggcgctctga aatggtattg tacttgaaat
    11581 ctgtcgtaga aaagatagtc gcgtcaggca taaaagtaac tttggtgcct gttttagact
    11641 tgggtgctgt accgattttc ttcaaagtcg tgacaggttt tccaccattt tcaaaacgtt
    11701 gcttgtaaac tgcgccatca cgggtaattt caacttctaa ccagctagaa agggcgttaa
    11761 caacggaaga acccactccg tgaagtccac ctgatgtctt atagccacct tgaccgaatt
    11821 tccctccggc atgaagaatg gtaaagataa cctcaacagt tggaattccc atagcgtgca
    11881 tacctgtcgg catcccacgt ccatggtctt gaaccgttag actaccgtct ttattgatag
    11941 ttacatcaat acgatcacca aacccagaca aggcttcatc gactgcatta tcaacgattt
    12001 cccaaactag gtgatgaaga ccagcgccat cggtcgatcc aatatacatc cctggacgtt
    12061 ttcggaccgc atccaaccct tctagcacct gaatagcatc atcattataa ttgttaatat
    12121 tgatttcctt ttttgacaca aggaacctcc tattcgttca tctttactat tctacaggtt
    12181 ttccaaggat tttgcaaaat ttttctttct ccgatgtgac aatttcagca gagattctct
    12241 gcttttcttt cccaattcat gatataatag gagtatgatt acaatagttt tattaatcct
    12301 agcctatctg ctgggttcga ttccatctgg tctctggatt ggacaagtat tctttcaaat
    12361 caatctacgc gagcatggtt ctggtaacac tggaacgacc aacaccttcc gcattttagg
    12421 taagaaagct ggtatggcaa cctttgtgat tgactttttc aaaggaaccc tagcaacgct
    12481 gcttccgatt atttttcatc tacaaggcgt ttctcctctc atctttggac ttttggctgt
    12541 tatcggccat accttcccta tatttgcagg atttaaaggt ggtaaggctg tcgcaaccag
    12601 tgctggagtg attttcggat ttgcgcctat cttctgtctc taccttgcga ttatcttctt
    12661 tggagctctc tatcttggca gtatgatttc actgtctagt gtcacagcat cgatcgcggc
    12721 tgttatcggg gttctgctct ttccactttt tggttttatc ctgagtaact atgactctct
    12781 cttcatcgct attatcttag cacttgctag tttgattatc attcgtcata aggacaatat
    12841 agctcgtatc aaaaataaaa ctgaaaattt ggtcccttgg ggattgaacc taacccatca
    12901 agatcctaaa aaataaaacg ccagttctgt actgacccca aaaagttaga caattaattt
    12961 atccgaagga tttagttctg tattgcacag ggctaagtcc ttttagtttt accttaattc
    13021 gtttattgtt gtagtaatca atatagtcta caatggcttg
//
LOCUS       DBERDS010000049        12925 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.049, whole genome shotgun sequence.
ACCESSION   DBERDS010000049 DBERDS010000000
VERSION     DBERDS010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.049"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            124..987
                     /locus_tag="ACL73E_001692"
     CDS             124..987
                     /locus_tag="ACL73E_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0801625.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1370..1990
                     /locus_tag="ACL73E_001693"
     CDS             1370..1990
                     /locus_tag="ACL73E_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801626.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2076..2519
                     /gene="tsaE"
                     /locus_tag="ACL73E_001694"
     CDS             2076..2519
                     /gene="tsaE"
                     /locus_tag="ACL73E_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGS0801627.1"
                     /translation="MYTKNEEELQALGESLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRADKLLEELQYGV"
     gene            2509..3027
                     /locus_tag="ACL73E_001695"
     CDS             2509..3027
                     /locus_tag="ACL73E_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGS0801628.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            3035..4051
                     /locus_tag="ACL73E_001696"
     CDS             3035..4051
                     /locus_tag="ACL73E_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGS0801629.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNLLRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4136..5392
                     /locus_tag="ACL73E_001697"
     CDS             4136..5392
                     /locus_tag="ACL73E_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGS0801630.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGNPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHVFNLVRKALLSD"
     gene            5447..6613
                     /gene="recA"
                     /locus_tag="ACL73E_001698"
     CDS             5447..6613
                     /gene="recA"
                     /locus_tag="ACL73E_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGS0801631.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6920..8290
                     /locus_tag="ACL73E_001699"
     CDS             6920..8290
                     /locus_tag="ACL73E_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGS0801632.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQSLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8666..9622
                     /gene="lytA"
                     /locus_tag="ACL73E_001700"
     CDS             8666..9622
                     /gene="lytA"
                     /locus_tag="ACL73E_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGS0801633.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9968..10129
                     /locus_tag="ACL73E_001701"
     CDS             9968..10129
                     /locus_tag="ACL73E_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0801634.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            10116..10322
                     /locus_tag="ACL73E_001702"
     CDS             10116..10322
                     /locus_tag="ACL73E_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801635.1"
                     /translation="MDLSNKASNLRKKLGADGESSIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            10335..10724
                     /locus_tag="ACL73E_001703"
                     /pseudo
     CDS             10335..10724
                     /locus_tag="ACL73E_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            10855..11280
                     /locus_tag="ACL73E_001704"
     CDS             10855..11280
                     /locus_tag="ACL73E_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801636.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            11688..12473
                     /locus_tag="ACL73E_001705"
     CDS             11688..12473
                     /locus_tag="ACL73E_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801637.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPFVSEFWNDFKNNH
                     DKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            12463..>12925
                     /locus_tag="ACL73E_001706"
     CDS             12463..>12925
                     /locus_tag="ACL73E_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801638.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCG"
BASE COUNT         4092 a         2066 c         2807 g         3960 t
ORIGIN      
        1 tttatgtaat ttttgacttt ttttagttta ttaccataaa gaattattta ttcctttaac
       61 ttgctatttt gaactaaaaa ttttataatg caattaagca aataggaagg tttattatct
      121 ttaatgaata cactcgcaga gaaattcaga ttgaaaagaa aagagttgag actctcccaa
      181 caaactcttg cagaaggaat ttgtgaacaa agccagatta gtaaaattga gagagggcat
      241 ttcattccct ccgcagacct tttgttcaaa ctctctcaac gacttgaagt accattagat
      301 tattttttta atgaacaaat tgaaattaaa tctaacctct ctaatttcaa gcaattgtct
      361 gctcgactat tagacgatag aaattatgac gatttggaat atatttatag aatagagatt
      421 gaacgaagta cttttctaac actagaagac cgaacttacc ttgaatggat taaagctatt
      481 attgacttct atcaatatga cagtaagtgt gaggcaattt cttcattgga aaatatatta
      541 ttaaaagtct cttcaaatac tctgatttat ttaaaggcgt tgaatactct atctaatttc
      601 tattccttag tgggtcgtga acaagaatat gaggcaaact actctcattt aatagagttg
      661 tatcagacaa aaaatttgga ccatcaagag tttttatttg gctacatcag agttcgttac
      721 aactacgctc actacctagt atcaaaggaa aaatataatg aagccatcca agaagctctt
      781 gaaacgattg aactctgtaa acaaagacag acaagctacc aattggctcc tctacttatt
      841 cttgtaggaa atgctggagc caaatttcta gacagagaac aagtcaaaaa ttattatata
      901 gaagcaagag agctatgcaa gatttataac aatcctttaa tgctgatgaa gatagaaaat
      961 tatttgaagg aactagatac tgtttagtta atcttgacat tatagttttt ctgaaacgtt
     1021 aaataacctg taaggctgat agttagatta atactatcag ccttataatt atgtgactct
     1081 gagtccgtct cgctccgtga ggtgcgagac aaaacaacca cccgtttgac ggattttcat
     1141 gatttcaaat ctatattctt cgaaaatctc ttcaaatcac gtcagctcta tctgcaatct
     1201 caaaacactg ttttgagcaa cctgtggcta gctacctagt ttgatctttg attttcattg
     1261 agtattagtc tctagtgttt gtttagcgtc ttaaagagac atttgagaag attagaaaca
     1321 gttctctctt ttctcctagt ataatgattg gtaggaaggg agagagaaga tgaaatcaat
     1381 gagaatctta tttttgttag ctttaattca aatcagtttg agtagctgtt tcctatggaa
     1441 ggaatgcatc ttgtccttta aacaaagtac agcttttttc atcggaagca tggttttcgt
     1501 ttcaggaatc tgtgctggag taaattatct ttatacccgt aagcaagaag tccatagtgt
     1561 cctagccagt aagaagtcgg tgaagctttt ttacagtatg ttactcttaa ttaatttgtt
     1621 aggagctgtt cttgttttgt cagataactt gttcatcaaa aatacgctgc agcaagaatt
     1681 agttgacttt ttattgccat ccttcttttt cctatttggg ctagatttgc tgattttttt
     1741 acccttgaaa aaatacgtgc gcgattttct tgctatgcta gacagaaaaa agacagtgtt
     1801 ggtgactatt ttagcaacac ttcttttctt aagaaatcca atgaccattg tctcacttct
     1861 gatttatatt ggactgggct tgttttttgc agcctatctt gtcccaaatt cggttaagaa
     1921 ggaagtttcc ttttatggtc atattttccg agatcttgta ttggtcattg ttacgctcat
     1981 tttcttttag agaaagcctg ttttttatgg atgttatgat gataagttta gtaggaaaat
     2041 agacacaaaa gaaaagtttt tggtataata agagtatgta cacaaaaaat gaagaagagt
     2101 tgcaagcctt aggggagagt ttgggccatc tattagcaaa gaatgatgtt ttaatcttaa
     2161 ctggagaact gggtgcaggt aaaacgacct ttactaaagg acttgcaaaa ggattacaga
     2221 tttctcaaat gattaaaagt cccacctata ctatcgtgag agagtatgaa ggtcgacttc
     2281 cactttatca cctagatgtt tatcgtattg aaggagatgc tgattctatc gacttggatg
     2341 agtttatctt tggtggtggc gtgactgtta ttgagtgggg aaatctctta ggagatgcct
     2401 tgccagatgc ttatttagaa ttggaaattc taaaagaagc agatggacgc cgtttaaatt
     2461 ttcaggcaaa gggtttgcgt gctgataaat tgttagagga gcttcaatat ggagtatgaa
     2521 ttgctcatta gggaagcaga gcccaaagat gcagctgaat tagtggcctt tttaaatcgt
     2581 gtgagtttgg agacagactt taccagccta gacggagatg gtattctctt gactagtgag
     2641 gagatggaaa tattcctcaa caagcaagct agttcggaca atcagataac cttacttgca
     2701 ttcttaaatg gcaaaattgc tggtattgta aatattacag ctgaccagcg taagagagtc
     2761 cgtcatattg gagatctctt cattgtgatt ggaaaaagat attggaataa tggcttggga
     2821 agtttgttgc tagaagaagc gatagagtgg gcacaagcaa gtggcattct gcgtcgtctc
     2881 caactgactg tccaaactcg taatcaagca gcagtccatc tttatcaaaa gcatggcttt
     2941 gtcattgaag gtagccaaga gcgtggggca tatatagaag aagggaaatt tatcgatgtt
     3001 tacttgatgg gtaaactgat aggttagtag aaatatggtt aaaaaaatta ttggaatggt
     3061 gctagcttta ctttctgtaa ctgtagtagg agtaggtgtt tttgcttata ctatttatca
     3121 acaagggaca gaaaccttag ctaaaaccta taaaaaaatc ggcgaagaaa ccaaggttat
     3181 tgaagcgact gaacctctaa ccattctgtt aatgggagtg gacaccggaa atgttgaacg
     3241 aactgaaact tgggtcggta gaagtgatag catgatcttg atgacagtga atcctaaaac
     3301 gaaaaaaaca acaatgatga gtttagagcg ggatattctg acgcgcattg aatcagggaa
     3361 tggtcaggct catgaagcga aactgaactc agcatatgca gatggtggag cagagcttgc
     3421 tatagaaacc attcaaaaaa tgatgaatat ccatattgat cgctatgtga tggtcaatat
     3481 gagaggattg caaaaactag tggatgcagt aggaggtatt acagtcaata atatcctagg
     3541 tttcccaatt tctatcagtg accaagaaga atttaatact atttctatcg gtgttgggga
     3601 gcaacatatt gggggagaag aagccctagt ctatgcacga atgcgttacc aagatcctga
     3661 gggggattat ggtcgtcaaa aacgtcaacg tgaagttatt caaaaagtca tggaaaaagc
     3721 tctcagttta aatagcattg gtcattatca agagattcta aaagctttga gtgacaatat
     3781 gcagaccaat attgatttgt ctgcaaaaag tatccctaac ttgctaggct ataaagattc
     3841 atttaaaacc attgaaactc agcagttgca gggtgaagga gagatacttc aaggtgtttc
     3901 ttaccagatt gtttcgagag cacatatgtt ggaaatgcaa aatctactcc gacgttcttt
     3961 gggacaagaa gaagttactc agcttgaaac caatgcggtt ttatttgaag atttatttgg
     4021 cagagcacct gttggtgatg aagataatta acttttgata caaataaaaa aatcaatcgt
     4081 aggaaaattc ctgcgatttt ttcaaaaaaa tacgaataga taggtaggag gaaacatgaa
     4141 agcagaaatc attgctgttg gaacagagat tttgacaggg cagattgtca acaccaatgc
     4201 ccagtttttg tcggaaaaac tagctgagat tggggtagat gtatattttc agacggctgt
     4261 aggagacaat gaagttcgtc tcttgtcttt gcttgagatt gccagtcaac gtagcagtct
     4321 ggtgattttg acaggcggtt tggggccaac tgaggacgac ctaaccaaac aaaccctagc
     4381 taaattttta gggaaagcat tagtctttga tcctcaggct caggagaagt tggatatctt
     4441 ttttaccctg cgaccagact atgcccgaac accgaataac gaaagacaag ctcaaattgt
     4501 agaaggagcg attccactgc caaacgaaac aggactggct gttggaggaa aattagaagt
     4561 agacggagtg acctatgtcg tccttccagg tccgccaagt gaattgaaac ccatggtctt
     4621 aaaccaactt ctacccaagt tgatgacagg gagcaagctg tattcccgag ttcttcgttt
     4681 ctttgggatt ggcgagagcc agttggttac gattttggct gatttaattg ataatcagat
     4741 cgatcctacc ttggcccctt atgccaagac aggagaagtc actctacgtc tgtcaacaaa
     4801 ggctagcagt caagaagagg cgaatcaagc gctggatatc ttggaaaatc aaatcttgga
     4861 ctgccagact ttcgaaggaa tttctttacg agacttttgc tatggttatg gggaagaaac
     4921 tagtttagcc agcattgtgg tagaagaact gaaaaggcaa gggaaaacca tcgcggctgc
     4981 agagagtttg acggcaggtc ttttccaagc taccgtggcg aatttttctg gagtttcaag
     5041 tatatttaag ggcggttttg tgacctatag cttggaggaa aaatcaagga tgttggatat
     5101 tcctgccaag aatttggaag aacatggtgt ggtgtctgaa tttacagctc agaagatggc
     5161 tgagcaggca cgaagcaaga cccagtctga ttttggaatt agtttgactg gagtggcagg
     5221 accagatagc ctagaaggaa acccagttgg gacagtcttc ataggcttgg cgcaagatca
     5281 aggaactgag gttatcaagg ttaatattgg aggcagaagc cgagcagatg tacgtcacat
     5341 tgcggttatg catgtcttta acctagttcg caaggcttta ttaagtgact aacttttgat
     5401 ataatagtag ataggtctga ggatcattag aatgtaggag aatagaatgg cgaaaaaacc
     5461 aaaaaaatta gaagaaattt caaaaaaatt tggggcagaa cgtgaaaagg ccttgaatga
     5521 cgctcttaaa ttgattgaga aagactttgg taaaggatca atcatgcgtt tgggtgaacg
     5581 tgcggagcaa aaggtgcaag tgatgagctc aggttcttta gctcttgaca ttgcccttgg
     5641 ctcaggtggt tatcctaagg gacgtatcat cgaaatctat ggcccagagt catctggtaa
     5701 gacaacggtt gcccttcatg cagttgcaca agcgcaaaaa gaaggtggga ttgctgcctt
     5761 tatcgatgcg gaacatgccc ttgatccagc ttatgctgcg gcccttggtg tcaatattga
     5821 cgaattgctc ttgtctcaac cagactcagg agagcaaggt cttgagattg cgggaaaatt
     5881 gattgactca ggtgcagttg atcttgtcgt agtcgactca gttgctgccc ttgttcctcg
     5941 tgcggaaatt gatggagata tcggagatag ccatgttggt ttgcaggctc gtatgatgag
     6001 ccaggccatg cgtaaacttg gcgcctctat caataaaacc aaaacaattg ccatttttat
     6061 caaccaattg cgtgaaaaag ttggagtgat gtttggaaat ccagaaacaa caccgggcgg
     6121 acgtgctttg aaattctatg cttcagtccg cttggatgtt cgtggtaata cacaaattaa
     6181 gggaactggt gaccaaaaag aaaccaatgt cggtaaagaa actaagatta aggttgtaaa
     6241 aaataaggta gctccaccgt ttaaggaagc cgtagttgaa attatgtacg gagaaggaat
     6301 ttctaagact ggtgagcttt tgaagattgc aagcgatttg gatattatca aaaaagcagg
     6361 ggcttggtat tcttacaaag atgaaaaaat tgggcaaggt tctgagaatg ctaagaaata
     6421 cttggcagag cacccagaaa tctttgatga aattgataag caagtccgtt ctaaatttgg
     6481 cttgattgat ggagaagaag tttcagaaca agatactgaa aacaaaaaag atgagccaaa
     6541 gaaagaagaa gcagtgaatg aagaagttac gcttgactta ggcgatgaac ttgaaatcga
     6601 aattgaagaa taagctgtta aagcagtgga gaaatccgct actttttcga tttttgattc
     6661 aggtttttag attatatata gtagcttgaa ataagatatg aacaactcta ttaggaaagt
     6721 caaattaatt tctagaaatg ttttagcagc tacagcgtac tattccaaac tcaaccaact
     6781 ataatagatc gaaactagaa tagtacacat ctacttctaa aacattgtta aaaatcgatt
     6841 tgactttcct tatttcattc cgctatatat aagtttgctg tttcttgtcg ctcctctgga
     6901 aagctgatat aatagcttta tgaataaaaa acgaacagtg gacctgatac atggtccgat
     6961 tcttccctcg ctcttaagct tcacctttcc aatcttgcta tcaaatattt ttcaacagct
     7021 ctataacact gctgatgtct tgattgttgg acgatttctt ggtcaagaat ccttggctgc
     7081 agtaggagcg acgacagcga tttttgacct gattgtaggt tttacacttg gtgttggcaa
     7141 tggcatgggg attgtcattg ctcgttatta tggggctcgg aatttcacta aaatcaagga
     7201 agcagtagca gccacctgga ttttaggtgc tcttttgagc attctagtta tgttgctggg
     7261 ctttcttggc ttgtatcctc tcttgcaata cttagatact cctgcagaaa ttcttcctca
     7321 atcttatcaa tatatttcta tgattgtgac ctgtgtaggt gtcagctttg cttataatct
     7381 ttttgcaggc ttgttgcggt ctattggtga cagtctagca gccctgggat ttctgatttt
     7441 ctctgccttg gttaatgtgg ttctggatct ctattttatt acgcaattgc atctgggagt
     7501 tcaatccgca ggacttgcta ctattatttc acaaggttta tcagcggttc tctgctttta
     7561 ttatattcgt aaaagtgtgc cagaactctt gccacggttt aaacatttca aatgggacaa
     7621 aagcttgtac gcggatctct tggagcaagg tttggctatg ggcttgatga gttcaattgt
     7681 atctatcggc agtgtgattt tacagtcttc tgttaataca tttggtgcag tgattattag
     7741 tgctcagacg gcagctcgac gcattatgac ctttgccctt cttcctatga ccgctatttc
     7801 tgcatcaatg acgacctttg cttctcagag tctaggagct aagcgacctg accgcattgc
     7861 tcaaggtctt cgaatcggca gtcgtttaag tatatcctgg gcagtttttg tttgtatttt
     7921 cctctttttt gccagtccag ccttggtttc cttcttggct agttcgacag atggttactt
     7981 gatagaaaat ggaagtctct atctgcaaat cagttcagcc ttttatccca ttttgagcct
     8041 cttgttgatt tatcgcaatt gcttgcaggg cttggggcaa aagatccttc ctctagtttc
     8101 tagctttatt gaactaatcg gaaaaatcgt ttttgtggtt ttgattattc cttgggcagg
     8161 atataagggt gttatccttt gtgaacctct tatctgggtt gccatgacag ttcaactgta
     8221 cttctcacta ttccgtcatc ccttgataaa agaaggaaag gcaattttgg caaccaaagt
     8281 gcaatcctag ttggatttac tgaataaaat ccatttcctc tagtgaacat cgaaaaaact
     8341 tgtgttctct tctttagttt ggtgttgaaa atagtttaac agacttttga cttcttttat
     8401 atgatataat aaagtatagt atttatgaaa aggacatata gagactgtaa aaatatactt
     8461 ttgaaaagct ttttagtctg gggtgttatt gtagatagaa tgcagacctt gtcagtccta
     8521 tttacagtgt caaaatagtg cgttttgagg ttctatctac aagcctaatc gtgactaaga
     8581 ttgtcttctt tgtaaggtag aaataaagga gtttctggtt ctggattgta aaaaatgagt
     8641 tgttttaatt gataaggagt agaatatgga aattaatgtg agtaaattaa gaacagattt
     8701 gcctcaagtc ggcgtgcaac catataggca agtacacgca cactcaactg ggaatccgca
     8761 ttcaaccgta cagaatgaag cggattatca ctggcggaaa gacccagaat taggtttttt
     8821 ctcgcacatt gttgggaacg gttgcatcat gcaggtagga cctgttgata atggtgcctg
     8881 ggacgttggg ggcggttgga atgctgagac ctatgcagcg gttgaactga ttgaaagcca
     8941 ttcaactaaa gaagagttca tgacggacta ccgcctttat atcgaactct tacgcaatct
     9001 agcagatgaa gcaggtttgc cgaaaacgct tgatacaggg agcttagctg gaattaaaac
     9061 gcacgagtat tgcacgaata accaaccaaa caaccactca gaccatgtgg atccataccc
     9121 ttacttggca aaatggggca ttagccgtga gcagtttaag catgatattg agaacggctt
     9181 gacgattgaa acaggctggc agaagaatga cactggctac tggtacgtac attcagacgg
     9241 ctcttatcca aaagacaagt ttgagaaaat caatggcact tggtactact ttgacagttc
     9301 aggctatatg cttgcagacc gctggaggaa gcacacagac ggcaactggt actggttcga
     9361 caactcaggc gaaatggcta caggctggaa gaaaatcgct gagaagtggt actattttga
     9421 tgtagaaggt gccatgaaga caggctgggt caagtacaag gacacttggt actacttaga
     9481 cgctaaagaa ggcgccatgg tatcaaatgc ctttatccag tcagcggacg gaacaggctg
     9541 gtactacctc aaaccagacg gaacactggc agataaacca gagttcacag tagagccaga
     9601 tggcttgatt acagtaaaat aataatggaa tgtctttcaa atcagaacag cgcatattat
     9661 taggtcttga aaaagcttaa tagtatgcgt tttcttgtgg agatatttcc ttcaatgttt
     9721 gctactatat taaacaaaaa tcagaaagcg aactagaaag ttatgctcaa ataaaatcta
     9781 aatttgacaa tgtaaaccga gtcggatagc tttaagtact gttttgaggt tgaagatacg
     9841 atttttgata ggaactcatc aattttagat ttttaagcag catcaataaa ttgcttcctt
     9901 gttttgtcat aattttttta tttaaaaaat tatgacaaga gtgtgctatt ctttttatga
     9961 gaggtgtatg aatatgataa atgtatgtga tgttggaaaa agaataaaag aacttagaat
    10021 atcttcaaat cttactcaag ataagattgc tgagtatttg tctttgaatc aaagcatgat
    10081 tgccaaaatg gaaaaaggtg aaaggaatat cacgaatgga tttaagtaat aaagcttcaa
    10141 atcttagaaa aaagttggga gctgatggtg aatcgtcgat agatattttt aaattggtac
    10201 aaaagataga aaatttgacg ctggtatttt atggactcgg aaagaatatt agcggagtct
    10261 gttataaagg aactcagttc agtctcattg cagtcaattc agacatgcca ttaggaaggt
    10321 aaagattttc tttagcacat ggactgtatc atctttatta tgatgaggtg aagaagagtt
    10381 cagtcagtct tatcttgatt ggtgaaggag atgaaactga aagaaaagcg gatcagtttg
    10441 cttcttattt tttaattttc ccatcttcac tgtataggat ggttgaggaa atcagagaaa
    10501 atgccaatag aactcatctt gaagtagaag atattataaa attgggtcag ttttatggta
    10561 tcagtcataa agctatgtta tatagattga gaaatgatgg ataccttgat gcagaagaaa
    10621 ttaaaaatat ggatattagt gttatagaga cagcttcaag attaggctat gatacaagtt
    10681 tatatcgtcc tttgtcagaa agtaaaaagg aaatggtatt aggacactat attaaatcga
    10741 ctgaacaact tttagaaaat aacagaattt cgcaagggaa gtatgaggaa ctgttactag
    10801 atgctttcag atatgatatt gtatatgggc tagatgaaga gggggagttg tcgtttgact
    10861 agtcgtgtat ttattgatgc agattgtatt tcagcatttt tatgggttgg cactgaacat
    10921 cttttagaaa agctctattc gggtaaaatt gttattccac aagaggtgta tgatgaaatc
    10981 aatataccta caattcccca tttaaaatct aggatagacc agttggtaac taagggttca
    11041 gctgagattg tgagcataga cattggaact gaagaatacg cattatatag agatttaaca
    11101 agaaatcatg atagtaacaa gattattggt aagggagaag cgacttctat tttcttagcg
    11161 aaaaagcata atgggatatt aggaagtaat aacctaagag atgttaaacc atatgtagaa
    11221 gaattttctt tagaacatat gacaacagga gatatactga ttgaagcgtt taaagcgtaa
    11281 tttattactg aacaagaggg caatcatatc tggaataata tgcttaaaaa gagaaggaaa
    11341 attggtgcaa attcattttc agactatctt cgtggaagta ttcatcaaaa tagacaaaaa
    11401 taaatttgga taaatcgaac tcactattca ggaggcatat gagcaattcg aaaaagaaaa
    11461 gtgtcaaatt gagcctatag gagtagaagt gaaatagtaa gtcctgcata gtggatgaga
    11521 gaaaagttct ccttgaagtt ttcctgaact atcagtcgca tgtcaaacga tatgtagggt
    11581 aatgtgagag gggatagcga gtagtttttg gttattttat caaaaaactt atattttatt
    11641 ataccgaatg ataaaatata ataaaaatga tagaataagg aaaaaacatg aatgtcaaaa
    11701 agataatgtc aatttttcaa tccttttatg ttgatgtcag tattgaggaa ctgactttga
    11761 ctttaccaat cagttttgta aaaaggtttg agtatactca aatgactttt cataaggaat
    11821 catttttatt gattaaagaa aagagaaggg ggagtttgag ttcatttgtt actcaggctc
    11881 gcactatggg tgaaaaagcc aatatggatg ttgttttggt gttttcgaag ttatcagaca
    11941 gtgaaaaaaa gcaattactt caagctagag ttccgtttgt agactttaag ggaaacctct
    12001 tcttccctcc attgggacta gtactcaatg cgaatgatac tgaaatccct aaggaattaa
    12061 cacctagcga acaattaacg tggattgcct ttttattgcc agatggcgat ataaagcaga
    12121 taaaatctgt ttctaacctt ctatatggtg gtgcttatgc tttgtcgcat tcaacttttt
    12181 tagctgaaac ggatgaaaat actagctatg tcatatggca gagaaaattc aatcagttat
    12241 ccttgccact ttctcagcat gttttaaaag gaaagatgct agagatatgg aaatatcgtc
    12301 cttttgtatc tgagttttgg aatgatttta aaaataatca tgataaacaa tttgtagatc
    12361 cgatttctct ttatttgacc ttaaaagatg atgatgaccc acgtatagag gaagagagtg
    12421 aagcactaga aaatatgata ttacagtatc tgggagaaga tgatgccagc taatacgaaa
    12481 gttatttttc aagaaatgtt tgcggatttt cagaactatt atgttctgat tgggggaact
    12541 gctacctcta tcgtattgga ttcgcaagga tttaaaagtc gcacaacaaa agattatgat
    12601 atggtcatca tttatgaagt aaaaaataag gaattttata ctaccttgaa tcatttttta
    12661 gaattgggag agtatcaagg aagtcagaaa gatgagaaag cgcagctttt tcgatttaca
    12721 acaactaatc ctgagtttcc ttctatgatt gaactattta gtatcttacc agaatatcca
    12781 ttaaagaagg acggtcgaga aattccctta cattttgacc aagatgccag tttatcagcc
    12841 ttattattgg atgaagatta ttataatata ttggtgcatg aaaaagaaac cattcagggg
    12901 tattcggtat tgagtaattg tggtt
//
LOCUS       DBERDS010000050        12539 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.050, whole genome shotgun sequence.
ACCESSION   DBERDS010000050 DBERDS010000000
VERSION     DBERDS010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.050"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            95..304
                     /locus_tag="ACL73E_001707"
                     /pseudo
     CDS             95..304
                     /locus_tag="ACL73E_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(511..2769)
                     /locus_tag="ACL73E_001708"
     CDS             complement(511..2769)
                     /locus_tag="ACL73E_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS0801639.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2998..3228)
                     /locus_tag="ACL73E_001709"
     CDS             complement(2998..3228)
                     /locus_tag="ACL73E_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGS0801640.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3418..4101
                     /locus_tag="ACL73E_001710"
     CDS             3418..4101
                     /locus_tag="ACL73E_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGS0801641.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4101..4835
                     /locus_tag="ACL73E_001711"
     CDS             4101..4835
                     /locus_tag="ACL73E_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGS0801642.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQILSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4989..5846
                     /locus_tag="ACL73E_001712"
     CDS             4989..5846
                     /locus_tag="ACL73E_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGS0801643.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5988..6860
                     /locus_tag="ACL73E_001713"
     CDS             5988..6860
                     /locus_tag="ACL73E_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGS0801644.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPESMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7142..7825
                     /gene="rpiA"
                     /locus_tag="ACL73E_001714"
     CDS             7142..7825
                     /gene="rpiA"
                     /locus_tag="ACL73E_001714"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGS0801645.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7839..9050
                     /locus_tag="ACL73E_001715"
     CDS             7839..9050
                     /locus_tag="ACL73E_001715"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGS0801646.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEADIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9052..9594
                     /locus_tag="ACL73E_001716"
     CDS             9052..9594
                     /locus_tag="ACL73E_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGS0801647.1"
                     /translation="MTRYALLVRGINVGSKNKVVMAELHQELTNLGLEKVESYINSGN
                     IFFASIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9610..10419
                     /locus_tag="ACL73E_001717"
     CDS             9610..10419
                     /locus_tag="ACL73E_001717"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS0801648.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKIDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10895..11290
                     /locus_tag="ACL73E_001718"
     CDS             10895..11290
                     /locus_tag="ACL73E_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGS0801649.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            11300..11875
                     /locus_tag="ACL73E_001719"
     CDS             11300..11875
                     /locus_tag="ACL73E_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGS0801650.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDGSGKEIE"
     gene            11900..12412
                     /locus_tag="ACL73E_001720"
     CDS             11900..12412
                     /locus_tag="ACL73E_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGS0801651.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         3728 a         2282 c         2822 g         3707 t
ORIGIN      
        1 aaataagaat aggataaatc gatcaggata gtaaaatcga attctaacaa tgttttagaa
       61 gtagatgtgt actattctag tttcaatcta ctatattatg gataatgcaa gattccatag
      121 aatggggaag ctagaacttt tatgcgaaga gtttgggcat aaacttttac ctcttcctcc
      181 ctactcgcct gagtacaatc ctattgagaa aacatgggct catatcaaaa agcacctcaa
      241 aaaggtatta ccaagttgcg atacctttta tgaggctctt ttgtcttgtt cttgtttcaa
      301 ttgactatag cagattgaaa taagatgaga acaaatcgat tgggaaagta aaattaattt
      361 ctataaatgt tttagcaatt gtttcgtact atttcagatt cagtctacta tatatcataa
      421 tggacaaagg gcaagctgtc aagaaattac agttatttta gtaaaaaaag aagcagaaaa
      481 atttcatttt ctactccttt tctataggat ttatttttct ttttcagaac ttttaacttc
      541 agcttttttg gcagatttaa tctgaatgtt tcccttgcta gtcataactg ctttgagatc
      601 tttttcgctt ggattttcaa ggtagtagtc agtgattgtg tcctcaatat agtcttgaat
      661 agtccgacga agtgggcgtg ctcccatttt tggatcataa cctaggtcaa ccaacttttc
      721 cttgacctta tcagttacat ccaaacgaat gttgttgcta gagaggcgct tgttaacatc
      781 tgctagcatg agctcgacaa tctgaaggag gttatccttg ctgagagcct taaattcgat
      841 aatgccatca aaacggttca taaactctgg gctaaagaag ttaccgagtt caccgaggac
      901 agaattggta cgtccttctc tagcagcacc aaatccaacg ctagcttcgg tctttcctgt
      961 acctgcattt gaggtcatga taatgatggc atccttgaag ctaacggtgc gtccttgccc
     1021 gtctgtcaaa cgaccatcgt ccaagacttg aagaaacatg tgcataacat ctgggtgagc
     1081 tttttccact tcatcgagaa ggatgagaga atatggattg tggcgaactt tttcagttaa
     1141 ttgaccagcc tcatcatagc caacataacc tggaggggcg ccgaccaact tagccacact
     1201 atgtttttcc atgtattcac tcatatcaaa gcgaatcata ctatcagcag aaccaaaaag
     1261 ttcgatagcc agttgtttgg aaagttctgt cttaccgaca ccagttggcc caacgaagag
     1321 gaagcttccg attgggcggt taggggtacc aagtccgaca cgattacggc gaatagcctt
     1381 ggcaatctta tcgactgcat catcttggcc aataacatga gacttgagat cttcggctag
     1441 atggatgagt tgagattgtt ctttctcttt caaatcacca acagggatat tggttttctg
     1501 ctcgataatg tgctcaatag ttttctcgct gatgatagga gtatcctggt ctgtgatctt
     1561 tttcttttgc atttccttat acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa
     1621 atcttcttct cgtgtagctt gagacttgag attttcagcc tcaatcaagc gctgatcaat
     1681 tactttagga tccacaaaat tcaaggtcaa gttcatctta gaaccagctt catctaggag
     1741 gtcaatggcc ttgtcaggca agaagcgatc ttggatgtag cgattggaaa gagttgcagc
     1801 tgcttcaatc gcagcatctg tatattgaac gtggtggtaa tcttcgtatt tcttttgaat
     1861 ccctttgaga atagtgattg tttcgtccac cgttggttca tcgactttaa caggctgcat
     1921 acgacgctcg agggcagcat ccttttcaat gatacggtat tcattgaggg tagtagcacc
     1981 gactagttgc agttctccac gagcaagggc tggcttgagg atatttcctg cgtccatatt
     2041 accatcactc gcagaaccag caccaacaat ttcatggatt tcatcgataa agaggatgat
     2101 gtcttcacgt ttgcgaattt cttccatgag tttttgcatg cgttcttcaa attgtcctcg
     2161 aatccccgtt ccttgaacta agctaaccac atccagacgg atgacttgtt taccttggag
     2221 tttatgtggc acatcgccat cgacaatttt ctgagctaga ccttcgacaa cggccgtttt
     2281 tccgacacca ggttcaccga taaggacagg attattcttg gttctacgat tgagaatctc
     2341 gatgacacgg ataatctcat cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc
     2401 aatttcagtt acattaatac caaattcttc cagcaggcct ttttcttggc taggtggcgg
     2461 agtttgagca gatccacgat tttgggaacc ataaccgccg tttccaccgt aacctccacc
     2521 tgattgggtt gggggaatag gaggagtatt gctagaaggt ctgaaattgt ttagatcatt
     2581 gaagaaatca ccaaagggat cgaagtcacg attgttcaga tccgtcatac ctttgaagag
     2641 gctattgtta ggatctgttt tgataatctt atagcagttt tgacagaggt caatttgttt
     2701 ttgttttcca ttgagattgg tgtaaagatg aattgttgag tcgttaattt tacagttttg
     2761 acaaagcata catctacctc atttctttct ttagcctgac ttgtttaaag gtcaaaaata
     2821 gtcaaattct atactctcat tataacagga ttggggtgta aagcaagtaa aaagattgaa
     2881 gctttgagaa gttgttacaa tgaaaatttt tgtgaatttg gactataaaa aaatcctatt
     2941 tgtgagacaa aaaggatttt acttagacat gcagggacaa tcccagcttg ttttagatta
     3001 gtagagaagt tcgtaaattt ccattgcgat taagtcaatg ctatcaaacg tatacgtttc
     3061 gcgatcttct acgtcacgaa gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc
     3121 aacttctgca acaacaactc cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt
     3181 tgccattgct tcaaggcggt tgatgattct aaccaaatgt gattccattt tgattctcct
     3241 tcatttctta tcgttactat tttaccataa aggaggccaa cttgactaga aaaaactaag
     3301 atttctcgct aattctgcta gtttaaagat ttttaaataa attggataaa aaatttaaat
     3361 tttaattcaa aacatgttat aatcatacag tattctattt tagaaagcag tgtgactatg
     3421 aatttttctt ttttacctaa gtatttacct tattttaact atggggctgt tgtgacgatt
     3481 cttatttcta tctgtgttat ctttttggga actattttgg gtgttgtctt ggcttttggg
     3541 caacgttcaa agtttaaacc gcttgtttgg ttggccaact tgtacgtttg gattttccgt
     3601 gggacaccga tgatggttca aattatgatt gcctttgctc ttatgcatat caatgctccg
     3661 actattcaga ttggaatttt aggtgttgat ttttcgcgtc tgattccagg gattttgatt
     3721 atctctatga atagtggtgc ttatgtttcg gagactgttc gtgccggaat caatgcggtt
     3781 ccaaaaggtc agctagaggc ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt
     3841 tatgtgattt tgccacaagc agtcaaaaat atcttgccag cattggggaa cgaatttatc
     3901 accattatca aggacagctc cctcttatca gctattgggg tcatggagtt gtggaatggg
     3961 gctacaacag tttctacaac aacctatcta cctttaacac cacttttatt tgcagcattt
     4021 tactacttga ttatgacctc tattctgaca gtagccttga aagcttttga aaaacatatg
     4081 ggacaaggag ataagaaata atgacagaaa ccttgataaa aattgaaaat ttacataaat
     4141 cttttggaaa gaatgaagta ttgaagggca tcaacctcga gattaaaaga ggagaagttg
     4201 tcgttatcat cggtccttca gggagtggga aatctacctt gcttcgctct atgaatttgt
     4261 tggaggaagc aaccaagggg aagcttatct ttgagggagt cgatattacg gacaagaaga
     4321 atgacctgtt tgccatgcgt gagaagatgg gcatggtttt ccaacaattt aacctctttc
     4381 ctaatatgac tgtgatggaa aatattacct tgtcacctat caagactaaa ggtgaaagca
     4441 gggaagttgc tgagaagaga gcccaagagc ttttggaaaa agttggtttg ccagataagg
     4501 cagacgctta tccacagatt ctgtcgggtg ggcaacaaca acggattgcc atcgcgcgtg
     4561 ggttggctat ggaaccagat gttttgctct ttgacgaacc aacttcagcc ttggatcctg
     4621 aaatggtagg tgaggtattg gctgttatgc aagaccttgc caagtcaggg atgactatgg
     4681 ttatcgtaac acatgagatg ggatttgccc gtgaggtggc agatcgtgtt atctttatgg
     4741 cagacggtgt ggttgttgaa gatgggacac ctgagcagat ttttgaacaa acccaagaac
     4801 aacggactaa agatttcttg agtaaggttt tataatctat tttaaaattt caagacaaga
     4861 ttagtgaaaa gttcaaccag agctttttct tatagtttga aactatagga taacctagga
     4921 aagaagtgtt agagggcact agcagttttt ggtataatgg aagatatttg aaagaaaaga
     4981 gaagtgatat gacacagatt attgatggga aagctttagc ggccaaattg caggggcagt
     5041 tggctgaaaa gactgcaaaa ttaaaggagg aaacagctct agtgcctggt ttggtagtga
     5101 ttttggttgg ggataatcca gccagccaag tctacgttcg caacaaggag aggtcagctc
     5161 ttgcggctgg ttcccgtagc gaagtagtgc gagttccaga gactattact caagaggaat
     5221 tgttagacct gattgctaaa tataatcagg atccagcttg gcatgggatt ttggtccagt
     5281 tgccattacc aaaacatatc gatgaagagg cggttttatt agccattgac ccagaaaagg
     5341 atgtggatgg tttccatccc ctaaacatgg gacgtctttg gtctggacat ccagtcatga
     5401 ttccctcgac acctgcagga attatggaaa tgtttcatga atatgggatt gacttggaag
     5461 gtaaaaatgc ggtcgtaatc ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc
     5521 ttttggctaa aaatgcgaca gtaaccttgg cccactcacg aactcataat cttgccaagg
     5581 tggctgctaa agcagatatt cttgtagtcg caatcggccg cgccaagttt gtgactgctg
     5641 actttgtcaa accaggtgcg gttgtcattg acgttgggat gaatcgagat gaaaatggga
     5701 agctctgtgg agatgttgat tatgaggcag ttgcaccact tgctagccat atcacgccag
     5761 tccctggagg tgtcggtcct atgaccatta ccatgctgat ggagcaaact tatcaagcag
     5821 cacttcggac attggataga aaataagaga aacattcgat taatagagtg tattttctat
     5881 agctatatct aaaatggcag aaatgaatat taaattttag atataagatt acaaaaggag
     5941 gtctgcgtct cctttttatt gtataataaa agtgagagga aaaaaggatg aaagtgatta
     6001 atcaaacctt attagaaaaa gttattattg aacgttctcg ttcaagtcat aaaggagatt
     6061 atggtcgtct gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg
     6121 ctttagcagc tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata
     6181 tcccggctct gcacagccat ttacctgagt ctatggcctt ttctcttcaa gaccagcaat
     6241 tgttaaaaga gcaattggag aaggcagaag ttgtcttgct ggggcctggt ttacgagacg
     6301 atgcttctgg agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt
     6361 tgattgtaga cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa
     6421 gccagcttat cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg
     6481 aaaagcaaaa ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt
     6541 tggtggagaa aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt
     6601 tacaggttgg tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga
     6661 tcgcaggatt tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga
     6721 cccatcttca ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga
     6781 cggaaatcag caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gagagggtaa
     6841 gcaaagataa acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat
     6901 tcttgaaatg cgcctgcttt aaggctaaac tagacgtatc aaagttaaga gtttgttttt
     6961 gtaactggaa agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt
     7021 ggtaaaaata aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt
     7081 ttacttgaat aaaaagcggt ttcatagtaa aataagaatt gagaatgatg gaggtaaatc
     7141 ggtggaaaat ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat
     7201 ggtcgttgga cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg
     7261 tatcaaggaa gaaggattgc agattacagc tgtaacaact tctagtgtga ccactaaaca
     7321 ggcagaaggc cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac
     7381 ggttgatggc gcagatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc
     7441 ccttctcatg gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga
     7501 aagcaagctg gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg
     7561 tgcagagcag gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa
     7621 agacggccaa cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt
     7681 cattgaaaat ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca
     7741 tggtttattc aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat
     7801 ttcaacttca aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc
     7861 atttggtggt actggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca
     7921 atgcaggggt tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt
     7981 tgaatgtccc aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta
     8041 agactgtagc agctgaaatc aatccaactg gatatgcaac aaaattagag gaagtatctc
     8101 ttggtaagga tactatgact ggacactggg aaatcatggg actcaacatt actgagcctt
     8161 tcgatacttt ctggaacgga ttcccagaag aaatcctgac aaaaattgaa gaattctcag
     8221 gacgcaaggt tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt
     8281 ttggaccacg tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt
     8341 tgcagattgc tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat
     8401 acgctcgttc gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt
     8461 atgtaggtga accaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc
     8521 cattttcccc aactgttttg gataaattga atgaggctga tatcgatact tatgctgtgg
     8581 gtaaaatcaa cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt
     8641 caaatagtca tggaattgat acactattga agactatggg acttgctgag tttgaaaaag
     8701 gattctcatt cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc
     8761 acggttaccg tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta
     8821 tgagagagaa tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag
     8881 gaacggatca cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa
     8941 atggtctcat tccagtagga cattttgcag atatttcagc gactgttgcc gataactttg
     9001 gtgtggaaac tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc
     9061 tatgctttgc tggtgagagg tatcaatgtt ggtagtaaga ataaggtcgt catggcggag
     9121 cttcatcaag aattgacaaa cttgggactg gaaaaggttg agagctacat caacagtggc
     9181 aatattttct ttgcttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc
     9241 tttgcagtcc attatccatt tattcagagc ttttctttac tgagtctaga ggactttgag
     9301 gcggaacttg aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc
     9361 ttttacactg agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg
     9421 aaagatgaag tgctttattt tggaaaactt gggattttct gggggaaatt ttctgaagaa
     9481 tcctattcta agactgccta tcagaagtat ttgctgaagg tgcctttcta ccgccacatt
     9541 actattcgta atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa ataataaagg
     9601 agacacacaa tgacattttt aaacaaaatc catgaaactg ctactttcct gaaagaaaag
     9661 ggaattgcag cccctgagtt cggtctaatc cttgggtcag gacttggaga attggcagaa
     9721 gaaatcgaaa atccagttgt agtagactat gctgagattc caaactgggg ccgttcaaca
     9781 gtagtcggtc atgctggtaa attggtatat ggtgaactgg caggtcgcaa ggtcttggct
     9841 cttcaagggc gtttccattt ctatgaaggg aatcctctgg aagtggtgac tttcccagtt
     9901 cgtgtgatga aagttcttgg atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc
     9961 agatttggtc ctggtacctt gatggctatc tcagaccata tcaacatgac ggggcaaaat
    10021 ccattgatgg gggaaaactt ggatgacttt ggcccacgtt tcccagatat gtctagggcc
    10081 tacacaccag aataccgtgc cactgcccat gaagtggcta aaaaacttaa tatcaagatt
    10141 gatgaaggtg tctatatcgg agttactggt ccgacttatg aaacaccagc agaaattcgt
    10201 tcctataaga cactgggagc agatgcagtt ggtatgtcta cggttcctga agttatcgtg
    10261 gcagcccact ctggcttgaa agttctggga atttcatgta tcactaactt tgcggctggt
    10321 ttccaagaag aactcaatca cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat
    10381 ttcaaaggct tgcttaaagc gattcttgct gaattgtaag aaaaaagatt taaaaggggg
    10441 agtgcctctg tcttttcagg attgactgcc tatccgtatt aaagaagaaa cagaggaata
    10501 ctatgagctt cttcctgctc ttataactga aagaagcgga agaataggtg tgtctgatct
    10561 gatagccagc attgtgaaag acaagattct aggatactag cattagcttc ctagccaagc
    10621 agactagtat gataaggaga gatgagaatg aattgacttt ctgaatttct cagtcttatc
    10681 atatatagca caatgagatt tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa
    10741 gaaataatga aaattggtca acgaattatg cgctttggca taaaaaatta agtatcggag
    10801 ttgtatctgt tgtagtcggc tttgatttct agctccagct ggaatttcag ccaatgaagt
    10861 aaagcaagat gtaacatctg aagtggtaat aggtgtgcta gattctaagg aggaattgaa
    10921 agagtcagaa aatgatgctc caaaactaga aactcctctt agagaggagc caagactagc
    10981 tcctcaaacg cttccggaag caagtgaagt tcttgaaaac aaaagggaag agtcaaaagt
    11041 agagataaca gagccagctc aagcggatga tatccgcaag gttgttgggg aattagccaa
    11101 ggatataagt attactaagt tgtatatgac aggtcattct cttggaggct acctagctca
    11161 gattgcagcg gttgaagatt accaaaaata tcctgatttt tataaccatg tattgaggaa
    11221 agtgacaact ttcagtgctc ctaaagtgat tacttccaga actgtttggg atgctaagaa
    11281 tggtttctga gatgttggtt tggaaagtcg taaattagct gttagtggaa aaattaagca
    11341 ttatgtggtt gataatgaca atgttgtgac tcccttgatt cataataatc gtgatattgt
    11401 tacatttaca ggtaattcac gctttaaaca ccgttctcgt ggctattttg aaagtccaat
    11461 gaatgatatt cctaacttta atattggtaa acaagctacc ttggataaac atggttatcg
    11521 tgatccgaaa ttggataaag cgcgattctt taagaaacag gctctacctc aatcttctag
    11581 tcaaccaagc gctgaaccaa tggaaaatat tgccttagga aaacaggtta ctcaaagttc
    11641 gacagctttc ggaggagatg ctagaagagc tgtggatggc aaagtcgatg gtaactatgg
    11701 tcacaattct gtcactcata caaacttcca atctaagcct tggtggcaag tagatttggc
    11761 taaagaagaa accattcgcc aaatcaatat ttacaaccga acagacactg cccaggatag
    11821 attggcaaac tttgatgtca ttcttttaga cggttctggt aaagaaattg agtgaaaacg
    11881 tataatatct cctaaagatg tgtcagcaca aattacgatt aaccataaaa aagcgcgcta
    11941 tgttcggatt gagctagaag gctataatgc cctcagtctt gcagaagttg aagttttccg
    12001 ctttatagct acgaatggtg aaacggcgat acaagtttct aagtcagttc aaccaatcag
    12061 tcagactcct gtgaaagata aaacattgac aattcaacac agtggagctt acattgcccg
    12121 ctactccata acttgggaag aagttacagt agataaagat ggaaaccaag ttgttcgtag
    12181 tcattcttgg gaaggaaacg gtcgcaacca gactgcaggt tttgtcctca acctcccaat
    12241 caaagaaaat atgagaaatc tgcgagttaa gattgagaaa aagacgggcc tactatggaa
    12301 tagatggcaa acaatctatg aaaacagacc aattttagct caaccccacc gtaaaattac
    12361 ccattggggt acgacattga attccaaggt gagtgacgat gatgtcttgt aatctgatgg
    12421 tacaatgaca gttagtttgt ctagtttata agaaagtact acctgagctt gaatagaact
    12481 caggtagctc tctgtgaaag aacaaaatta atactcaatg aaaatcaaag agcaaacta
//
LOCUS       DBERDS010000051        12011 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.051, whole genome shotgun sequence.
ACCESSION   DBERDS010000051 DBERDS010000000
VERSION     DBERDS010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.051"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            204..857
                     /locus_tag="ACL73E_001721"
     CDS             204..857
                     /locus_tag="ACL73E_001721"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGS0801652.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANTFLKETGQEPIDWLR"
     gene            867..1331
                     /locus_tag="ACL73E_001722"
     CDS             867..1331
                     /locus_tag="ACL73E_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGS0801653.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPELDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1344..2612
                     /locus_tag="ACL73E_001723"
     CDS             1344..2612
                     /locus_tag="ACL73E_001723"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGS0801654.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGHVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2626..2886
                     /locus_tag="ACL73E_001724"
     CDS             2626..2886
                     /locus_tag="ACL73E_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801655.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2897..4258
                     /gene="pdrM"
                     /locus_tag="ACL73E_001725"
     CDS             2897..4258
                     /gene="pdrM"
                     /locus_tag="ACL73E_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGS0801656.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4412..5380
                     /locus_tag="ACL73E_001726"
     CDS             4412..5380
                     /locus_tag="ACL73E_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGS0801657.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5396..6388
                     /locus_tag="ACL73E_001727"
     CDS             5396..6388
                     /locus_tag="ACL73E_001727"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGS0801658.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6606..7649
                     /locus_tag="ACL73E_001728"
     CDS             6606..7649
                     /locus_tag="ACL73E_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGS0801659.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGIQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7695..9398
                     /gene="lpdA"
                     /locus_tag="ACL73E_001729"
     CDS             7695..9398
                     /gene="lpdA"
                     /locus_tag="ACL73E_001729"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGS0801660.1"
                     /translation="MALEIIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            9462..10451
                     /locus_tag="ACL73E_001730"
     CDS             9462..10451
                     /locus_tag="ACL73E_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGS0801661.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10518..11588)
                     /gene="xerS"
                     /locus_tag="ACL73E_001731"
     CDS             complement(10518..11588)
                     /gene="xerS"
                     /locus_tag="ACL73E_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGS0801662.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3582 a         2238 c         2671 g         3520 t
ORIGIN      
        1 cagaaaagat aatcttcgaa agaggtagta aaatgcttaa tgatttaaaa agtaattata
       61 aaaaatagcc agtctttata aactgtattc acgtattcaa atcgtatata gtcgatttat
      121 taaatcttta gataaactgt aaaaagtggt ttccatagcc actttttgct ataatagagg
      181 cagtaaaaat gaaggagtcg gctatggaac actcgtcttg gcatgctttg attaaggcgc
      241 aattacctga gggttatttc gggaaaatca atcagtttat ggagcaggtc tattctcagg
      301 ggattattta tccacccaag gaaaaggttt ttcaggctct cttgacaaca ctgcttgaag
      361 aagttaaggt ggtaattcta gggcaagacc cctatcacgg accaggtcaa gcgcagggct
      421 tgagtttttc cgtacctgac tctatcccag ctccaccatc cttgcaaaat atcttgaaag
      481 aattgtcaga tgatatcgga gttaagaaat ctcatgattt gacagcttgg gctgagcaag
      541 gagtcttgct tcttaatgct tgtttgactg ttcctgctgg acaggccaat ggtcatgctg
      601 gtcaaatctg ggagcctttt actgatgctg tgattcaggt ggtcaatcat ctagatagac
      661 cagtcgtttt tgtactctgg ggagcttatg cacgtaagaa gaaggcctta gttaccaatc
      721 ctcatcactt gattattgaa tcagcccatc caagtccttt gtcggtttat agaggatttt
      781 ggggttccaa gcctttttcc aaggccaata cattcttaaa agagacagga caagagccaa
      841 tcgattggct tagataagga gaaaatatgc ctcagttagc gacgatttgt tacattgata
      901 atgggaaaga actgctcatg ctccatcgta ataagaaacc caatgatgtc catgaaggga
      961 aatggattgg tgtgggtggt aagctagaga gaggagagac gccccaggaa tgcgcggtac
     1021 gtgaaatcct tgaagaaaca gggctcaaag ccaagccagt tctaaaaggt gtcatcactt
     1081 ttcctgaatt tacaccagaa ttagactggt acacctatgt ttttaaggtg acggagtttg
     1141 agggcgactt gattgactgc aatgagggga tgctagaatg ggttccctat gatgaggttt
     1201 tgagcaagcc gacttgggaa ggtgaccaca cctttgttga gtggctttta gaggataaac
     1261 ccttcttttc agccaagttt gtttatgatg gggataaatt gttggatacc caagttgatt
     1321 tctatgaata aaggagaaag cagatgctac taatcaaaaa tggtcgtgta atggatccca
     1381 agtctggttt ggatcaagtt tgtgatgtct tagttcaaga tgggaaaatt atcaaaattg
     1441 cgcctgagat cacggaagaa ggagcagaaa cgattgatgc tactggtcat gtggttgctc
     1501 ctggtttggt cgatattcat gtgcatttcc gtgaacctgg tcaaacacat aaagaagaca
     1561 ttcatactgg tgccctagca gccgctgcag gtggttttac tactgtcgtc atgatggcta
     1621 ataccagtcc aaccatttca gacgtggaga ctttgcaagc agttctccag tcagctgcca
     1681 aagagaagat taatgtcaag acagttgcga ccattactaa aaactttaat ggtaaaaact
     1741 tgactgactt taaggcactt ttagaagctg gtgcggttgg tttctctgat gacggtattc
     1801 cgcttgagag cagtaagatt gtcaaggaag ccatggagga agccaaaaaa ctcaatacct
     1861 ttatcagcct tcatgaggaa gatccaggtt tgaacggtgt tcttggcttt aatgaaaata
     1921 ttgctagaga acatttccat atctgtggtg ctactggggt ggctgagtac gctatgatgg
     1981 cgcgtgatgt catgattgcc tatgcaacta aagcccatgt tcacatccag catttgtcta
     2041 aggaagaaag tgttaaagta gtggagtttg ctcaggggtt aggtgcagaa gtcacagcag
     2101 aagtagcacc acagcatttc tctaagacag aagcacttct tttaacacaa ggtagcaatg
     2161 ctaagatgaa tccaccgctt cgtttggaat cagaccgtcg tgccgttatc gaaggtctca
     2221 aatcaggtgt catcacagtt attgcgactg accacgcgcc tcatcatgta gatgaaaaaa
     2281 atgttgaaga tattaccaaa gcgccatctg gtatgactgg cttagaaaca tccctgtctc
     2341 tcggcttgac ctatttggta gaagctggtg agttgagctt gatggaatta cttgaaaaaa
     2401 tgacatacaa cccagccaag ctttacaact ttaaagcagg ttacttggct gagaatggtc
     2461 cagcagatat cactattttt gatgccaagg ctgaccgcct tgtggactcc cattttgctt
     2521 ccaaagcagc taattcacca ttcatcggtg aaaccttaaa agggcaggtt aaatatacca
     2581 tctgtaaggg acaaatcgtc tatcaagctt gataggagtt agaatatgaa ttattttcga
     2641 aaacgtaggg agagacaagc gaaatctaat agtggaattt actgtcccgc agctaatcgt
     2701 tccaaaattc aatatgaaac taaagaaaaa gctgaccatg cggttcaata tgataacgga
     2761 ggtttagtta gaagctatta ttgtcgtaca tgtgcgtgtt ggcatactac ttcaaaatct
     2821 aataaacctc cgctaagttt gaaaaactat ggtctgaaac tctttggttt agataaatca
     2881 gaatagaaag agaagtatgt ataagacaaa gtgtttacga gagaagttag tattattttt
     2941 aaaaattttc ttcccaatcc tgatctacca atttgccaat tattctgcct cttttgttga
     3001 tactgcaatg acaggtcaat acaacactat ggacttggct ggtgtatcta tggcaaccag
     3061 tatctggaat cctttcttta catttctaac agggattgtg tcagccttgg tgcctatcat
     3121 tggtcaccat cttggtcgag gcaaaaagga agaagttgcg tctgattttt accaatttat
     3181 ttatttggcc ttgggcctat ctgtggtctt gctggggatg gtacttttct tggcaccaac
     3241 aatcttgaat catattgggt tagaagcagc agtagcggca gtagcggttc gctatctttg
     3301 gtttttatct atcgggatta tccccttgtt gctctttagc gtcattcgtt ccttgctgga
     3361 ttcgctgggc ttgaccaaac tgtccatgta cctcatgctt ttgttactcc ctctcaatag
     3421 cggatttaac tatctcttga tttacggtgc ctttggtgtt ccagaactgg gaggggctgg
     3481 tgctggttta ggaacatcct tggcctactg ggtcttgctt gggatttctg ttctggtttt
     3541 atttaaacag gagaagctca aagccttaca ccttgagaaa cgaattccac ttaatatgga
     3601 taacattaag gaaggagttc gtttaggtct gcctattggg ggaactgtct tcgcggaagt
     3661 ggctatcttt tcagtggttg gcttgattat ggctaagttt tcgtccttga ttatagctag
     3721 tcaccagtca gctatgaact tttcaagtct tatgtacgcc tttcctatga gtatctcatc
     3781 ggctatggct attgtcgttt cctatgaagt gggagccaag cgatttgatg atgcgaaaac
     3841 ctatattggt ctaggaagat ggactgctct catttttgcg gccttcaccc taaccttcct
     3901 ttacattttt aggggaaatg tggccagtct ttatggtaac gacccaaaat ttatcgattt
     3961 gacagcgcgt tttttaactt atagtctttt cttccagtta gcagatacct ttgcggcacc
     4021 gcttcaggga attttgcggg ggtataagga tacagttatt cctttttacc ttggtttgct
     4081 tggttattgg ggcgtagcaa tccctgtggc tacgctattt gattccctaa cagattttgg
     4141 agcttattct tactggatcg gcttgattat tagtttgatt gtgagtgggg cgctctaccg
     4201 ttggcgttta actgtgatta tgaagagatt tgaatcttta gcaaaatcca aacgctaaaa
     4261 agtttgtgaa aaaatatcct tgacaagaaa atcccttgtt ttcacggggt tttctttttt
     4321 attttgtgaa atttctttta gaaaaacttt gacagtattt gccaaaaacg gtaaaatagt
     4381 aaggtaagaa gaaagttaga aaggcaagaa gatgtcaact ttagataaaa atcttttgct
     4441 agaaatgttc cgtaagatgg aagaaatccg tcgcatggac ttaaaaattg cacaattagt
     4501 aaagaaaggg aaagtgccag gaatgacgca cttttctgtt ggtgaagagg cagctaacgt
     4561 gggggctatg ttagctctca atccagatga tctgattacc tcaaaccacc gtggacacgg
     4621 gcaagctatt gctaaaggga ttgacctcaa cggaatgatg gctgaaatcc ttggtaaata
     4681 cactggaacc tgtaaaggga aaggtggatc tatgcatatc gctgaccttg atgctgggaa
     4741 ccttggtgcc aatggtatcg taggtggtgg tatggggatc gctgtcggtg cagccctcag
     4801 tcagcaaatg caaaataccg gtaaaatcgt tgtttgcttc tttggagatg gtgcgaccaa
     4861 tgaaggtgtt ttccacgaag cagtgaacat ggcttctatc tggaacctgc cagtcatttt
     4921 ctattgcatt aacaacggtt acggtatctc tgcggatatc aagaaaatga ccaatataga
     4981 acatatccat caacgtagcg ccgcttatgg aattcctgga atgttcatcg aagacggtaa
     5041 caatgtcatc gatgtctatg aaggatttca gaaagctgta gaccatgttc gcagtggcaa
     5101 tggtccagtc ttgattgaaa gtgtaactta tcgctggctc ggtcactcat catctgaccc
     5161 tggtaaatat cgtacgcgtg aagaagtgga attgtggaaa caaaaagatc caatcgaaaa
     5221 cctccgcaat taccttattg aaaataacat tgcaagtgcc gaagaattgg aagaaatcca
     5281 agcgcaagta aaggaagcag tagaagcttc tgttaaattt gcagaggaaa gcccattccc
     5341 accgcttgaa tcagcctttg aagatattta cgcagactaa ggagaaagag ataaaatgga
     5401 aacaaaaaca atgtccttcc gtgacaccat tatccttgct atgtctgagg aaatgcgtcg
     5461 cgatgaaaat gtgttcttga tgggagaaga cgtcggtgtc ttcggaggag acttcggtac
     5521 ttctgttgga atgcttgaag aatttggtcc agaacgcgtc cgtgactgtc cgatttctga
     5581 agctgccatc tctggagcag cagcaggagc agccatgaca ggacttcgtc caatcgtcga
     5641 tatgaccttc atggacttct ctgttattgc catggacaat atcgtcaacc aagctgctaa
     5701 aacacgttac atgtttggtg gtaaaggtca ggttccaatg actgttcgtt gtgcagctgg
     5761 taacggagtt ggctctgccg cccagcactc acaatctcta gagtcttggt ttactcacat
     5821 tccaggactt aaggttgtgg cacctggaac acctgcggac atgaaaggcc tgcttaagtc
     5881 ttctatccgt gataaaaacc cagttattat acttgagtac aagtcagaat ttaaccaaaa
     5941 aggggaagtg ccagttgatc cagactacac aattccactt ggggttggtg aaatcaaacg
     6001 ccaaggaacg gatgtaacag ttgttactta tggaaaaatg cttcgccgtg tggttcaagc
     6061 tgctgaagaa ttagcagaag aaggaatttc agttgaaatt gttgacccac gtacccttgt
     6121 tccgcttgat aaggatatca tcataaactc agtgaagaag actggtaagg ttgttctggt
     6181 caacgatgcc cacaaaacaa gtggctatat cggtgaaatt tcagctatta tttcagaatc
     6241 agaagcattt gactatctag atgcaccaat ccgccgttgt gcaggagaag atgtgccgat
     6301 gccttatgca caaaacctag aaaatgcaat gattccaaca gttgaaagta tcaaagatgc
     6361 aatccgaaaa acttataaca aagaatagag ttacataaga taagttatgt aaataaaata
     6421 aagctgacga gaaactttgt atcttttagg tgcagagctc ttcgtcatta atatcttaga
     6481 ttagagcacg ggctaaaagc tcggaaaaaa gataaatctc cttggcttca tcgaagccat
     6541 cgtcgatttc ctatttttca gtcgcttttg acgccctttg tatcataaat agaattggag
     6601 aggtcatggc tgatgacaag ctaagagcga ctcctgcagc tagaaagtta gcggatgatt
     6661 tagggataaa cctctacgac gtttctggct caggtgcaaa cggtcgtgtc cacaaagaag
     6721 acgtggaaac ttataaagac acaaacgtgg ttcgcatttc gccacttgca aaacgaattg
     6781 ccctcgaaca taacattgct tggcaggaaa tccaaggaac cggtcatcgt ggtaaaatca
     6841 tgaagaagga tgttttggcc ctgcttcctg aaaatatcga aaacgatagc atcaaatctc
     6901 ctgctcagat tgaaaaagtg gaagaagttc ctgataacgt aacaccatat ggtgaaatcg
     6961 agcgtattcc aatgacacca atgcgtaagg ttattgccca acgcatggtt gaatcttact
     7021 tgactgcgcc aaccttcacc ctcaactatg aagttgatat gactgaaatg ttggctcttc
     7081 gtaagagggt tcttgagcca atcatggaag caactgggaa gaagactact gtaacagacc
     7141 ttctttcact tgcagttgtt aagactctta tgaaacatcc atacatcaac gcttcattga
     7201 cagaagatgg caagactatt atcactcaca actatgtcaa tcttgctatg gcagttggga
     7261 tggataatgg attgatgaca cctgttgttt acaatgctga gaagatgagt ctttcagaac
     7321 tggttgtagc ctttaaggat gttattggcc gtaccttgga tggtaaattg gctccaagtg
     7381 agttacaaaa ttcaacattc acaatcagta atttgggaat gtttggtatt cagtcctttg
     7441 gtccgattat taaccaaccc aactcagcta tccttggtgt cagttcgaca atcgagaagc
     7501 cagttgtcgt caatggtgaa attgtgattc gcccaatcat gagtttagga ttaaccattg
     7561 accaccgtgt cgtagatggt atggctggtg ctaagtttat gaaggacttg aaagagttga
     7621 ttgaaacccc aatctcaatg ttgatttaag agcaagagta ttcattttta agatatagat
     7681 aaaggaagga agacatggcc ttagaaataa ttatgccaaa agccggcgtg gatatgacag
     7741 aaggacaaat cgtccaatgg aataaaaaag tcggagaatt tgtaaaagaa ggagaaatcc
     7801 ttttggaaat catgactgat aaagtcagca tggaattgga agccgaagaa gatgggtact
     7861 tgattgccat tctcaaagga gatggtgaaa ctgtccctgt aacggaagtt atcggttacc
     7921 ttggtgaaga aagggaaaac atcccaacag ctggagcagc atcgccagaa gctagccctg
     7981 tacctgtagc aagtacctca aacgatgatg gtaagagcga tgatgctttt gatatcgttg
     8041 tgattggtgg aggtcctgct ggttatgttg cagccattaa agctgcccaa ctcggcggta
     8101 aggttgccct tgttgagaaa tctgaacttg gtggaacctg cttaaaccgt ggatgtattc
     8161 caaccaagac ctaccttcat aacgctgaaa ttattgaaaa tatcggtcat gctgcaaatc
     8221 gtggtatcgt gattgaaaat cctaacttca ctgttgatat ggaaaaactt ttagaaacta
     8281 aatctaaagt tgttaatact cttgttggtg gtgttgcagg acttcttcgt agctacggag
     8341 ttactgttca taaaggaatt ggtacaatca ctaaagacaa gaacgtcttg gtaaatggct
     8401 ctgaattgct tgaaaccaag aaaatcattc ttgctggtgg ttcaaaagtc agcaagatca
     8461 atgtccctgg tatggaatct ccacttgtca tgactagtga tgacattctt gaaatgaacg
     8521 aagtgccaga aagccttgtt atcatcggtg gtggagttgt cggtatcgaa ctcggtcagg
     8581 ccttcatgac atttggttca aaagtgactg ttatcgaaat gatggaccgt atagttccag
     8641 ctatggatgc ggaagtttct aagaaccttc gcttgatcct tgagcgtaaa ggaatgacca
     8701 tcttgactgg tactaaactg caagaaatca ttgaggaaaa tggtcaactt cgtatcaagg
     8761 ttgaaggaaa agacgatatc atcgcaagca aagctcttct ttcaattggt cgtatgccag
     8821 accttgaagg tattggagag gttgagtttg aattggatcg tggttgtatc aaggtcaatg
     8881 aatacatgga aacttcagtt ccaggcattt atgcaccagg tgacatcaac ggtactaaga
     8941 tgttggctca cgcagctttc cgcatgggtg aagtttccgc tgaaaatgcc cttaaaggaa
     9001 atcatgcagt tgccaaattg aatttgactc ctgcagccat ctacactctc cctgaagtag
     9061 cagcagtagg tttgacagaa gaacaagccc gtgagaaata cgatgttgcc atcggtaagt
     9121 ttaactttgc tgctaacggt cgtgctattg catctgacgc agctcaaggt ttcgtaaaag
     9181 ttatcgctga taagaaatac ggagaaatcc ttggtgtaca cattattggt cctgcagccg
     9241 cagaattaat aaacgaagca tcaagcatca tcgaaatgga aatcactgtt gaggaaatgc
     9301 tgaagaccat ccacgggcac ccaacttact ctgaagtgat gtacgaagcg tttgcagatg
     9361 ttctaggaat ggccatccat tcacctaaga aaaaataaaa cgaagataga ttagactgga
     9421 aggttatttc cagtctctat catataaagt aaagggatat catgaaatac attatcaatc
     9481 attcaaatga cactgctttt aatattgcct tggaagaata cgcctttaaa caccttttgg
     9541 atgaggatca aatcttccta ctttggatta acaagccatc tatcattgtt ggtcgtcacc
     9601 agaacactat cgaagaaatc aaccgtgatt atgttcgcga aaatggtatt gaggtagttc
     9661 gccgtattag tggtggtgga gctgtttacc acgatttaaa taacctcaac tacacgatca
     9721 tctccaaaga agatgaaaat aaggcatttg acttcaagag cttctcaact ccggttatca
     9781 ataccctggc tcaacttggg gttaaagctg agttcacagg tcgtaatgac cttgagattg
     9841 atggtaagaa gttctgtggc aatgcccaag cctatatcaa cggccgtatc atgcaccacg
     9901 gttgcttgct ctttgacgtt gatttgtcag tcctcgcaaa tgcccttaag gtttcaaaag
     9961 ataaatttga atcaaaaggt gtgaaatccg tccgtgcccg tgtaaccaat attatcaatg
    10021 aattaccaaa aaaaatcaca gtcgaaaaat tccgtgattt actcctggaa tacatgaaaa
    10081 aagagtaccc agagatgact gaatacgtct tttcagaaga agaattggcc gaaatcaatc
    10141 acatcaagga tactaagttt ggaacttggg actggaacta tggtaaatca cctgaattta
    10201 acgtccgtcg tggaaccaaa ttcactagtg gtaaggttga agtctttgct aacgttactg
    10261 aatcaaaaat ccaagacatc aagatttatg gtgacttctt tggtattgaa gacgttgctg
    10321 cagtagaaga tgtccttcgt ggggtgaaat acgaacgcga agatgttctt aaggcgctaa
    10381 aaaccattga tatcacacgc tacttcgctg gtattagccg tgaagaaatc gctgaagcgg
    10441 tagttggata aatcaaaaaa agaagttggc caacttcttt ttttgatatt tatttacata
    10501 atttaaaata cgtaaaatca taaactatct agagcattct tttgttcatc attaacaata
    10561 tgggtataga ggtcagtgac ttgtgtgctg gcatgtccta gttggtgact gactaaaact
    10621 tgtgatttag tcgcatcata gagcctagtt gctagcgtat ggcgcagttt atggggtgtt
    10681 acacgcactt taaaatcctc tgagtattta gcaaccattt tctcaacgct agaagcatcg
    10741 atacgattag gaacacctct gtagagagtt aaaaaaaggg ctgtatctgt tttttccgtt
    10801 ttatagcgtt gattccgaat ggccagataa ttctctaaat aaggtttagc aaaagcagcg
    10861 acattgactg agtcacgttt gccacctttt cgagtaacat caataaccat catttttaga
    10921 ttgagatctc ttagatctag attaacagct tcagataagc gaacaccaga tgccaagaga
    10981 agggcaataa tggctaaatc tcgttcttta tttttgttga atgatgagag agctcgattt
    11041 gaaagctgtt gtgggtgctc ttgatcgata taagttagaa aaccttctgt ttcatcacct
    11101 agaaagagtt tttgcttgat attttcagct ctggcagcaa gggtttcttt ctttttcttg
    11161 gttgaaactt ttttcattac attacgatag aaataaggtt ccccctgatc gttttcaacc
    11221 tcctcggtta gatacttgta aagactagaa agtgctgata aggttcgatt gatagttgtc
    11281 tgtgaaacac cttgttttgt tgtattagca ttcagcaagg gacgttcacg tagataaagg
    11341 ataaaggatt ccatgtcttt cttagacata ttttccaaaa ctgataaagg aatatcggat
    11401 attttatcag cgtttgaaat accagactcc aaaacccagc tgaaaaatcg gtcatattcc
    11461 ttaaggtatt cgtacagggt tgtaaaactg tagggcacag ccagcttaga ttggtagtat
    11521 tccagaacat accagggcat gagttgtttt agtttgtcga ttcgttccag taaaatctca
    11581 cgtttcatgt attttctcca taagtaagta tactagtagt atagcataga cttgtatatt
    11641 tttcaagaaa attatagttt ttctgaaaga tgttatagga gtttttcaaa gtgataaaaa
    11701 gacttagacc tacaaacaaa acagaataag gaaaataata aaaatctcac ccactaaact
    11761 tctgttaata ctacataact gaagagctat ataaggagct atgagataca aaacacattg
    11821 tataatagat tgaaactaga atagtacatc tgaacttcta aaacattgct agaaattgat
    11881 ttgattgtcc tgattgtttt atcctatttc tatttcattt cactatataa ttgctattgt
    11941 tttctttttc atgattttaa tcttactgta cagatttgat acagtaaact cctttctagc
    12001 tttatacttt a
//
LOCUS       DBERDS010000052        11803 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.052, whole genome shotgun sequence.
ACCESSION   DBERDS010000052 DBERDS010000000
VERSION     DBERDS010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.052"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL73E_001732"
     CDS             371..598
                     /locus_tag="ACL73E_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801663.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="ACL73E_001733"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="ACL73E_001733"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGS0801664.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGIEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4797..5249
                     /locus_tag="ACL73E_001734"
     CDS             4797..5249
                     /locus_tag="ACL73E_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGS0801665.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5268..6605
                     /locus_tag="ACL73E_001735"
     CDS             5268..6605
                     /locus_tag="ACL73E_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0801666.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6684..7568
                     /locus_tag="ACL73E_001736"
     CDS             6684..7568
                     /locus_tag="ACL73E_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0801667.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7568..8401
                     /locus_tag="ACL73E_001737"
     CDS             7568..8401
                     /locus_tag="ACL73E_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGS0801668.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8419..10512
                     /gene="nanB"
                     /locus_tag="ACL73E_001738"
     CDS             8419..10512
                     /gene="nanB"
                     /locus_tag="ACL73E_001738"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGS0801669.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPALIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGDSQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSSSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10524..11627
                     /locus_tag="ACL73E_001739"
     CDS             10524..11627
                     /locus_tag="ACL73E_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGS0801670.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
BASE COUNT         3990 a         1832 c         2448 g         3533 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 agggagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattag gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tccatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aagaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga gggagaaaag gaagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 aaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaaaatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacacttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacaag aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtatagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaatt attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatatgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaagtata ctctaattga aaacggtaac aaaactaatt tagagaatga
     4261 aatatagagt atttctctct taaaagtttt tggtgaaacg agatgtagaa aggagattta
     4321 gccaaagagt ctattagtgc tagaataata gattagaatt attttagaaa aacgaagtga
     4381 gcagcttata aattcaagtc cccaaataga ttcatactag tatcttttgc aaaaaataaa
     4441 gggcgacttc cttcatgaat atcaatttca tctataagga aggtagctaa ttgaactaac
     4501 ttatttattc tgtttgtcgc tagaaaaatc agacctcctt gtgaagattg aggagatact
     4561 taatgaaaat caaagaagaa actagcaagc tagtagcaga ttgcccaaaa caccgctttg
     4621 aggttgtaga taagactgac ctatataatc caaggtgaag cgactgtggt ttgaagagat
     4681 tttcaaagag tataggctag agagtagtgt ttttatgtcc ttctagtaga aaatgctaga
     4741 cagaagaatg gggaacttgg ataggaaaaa tagattgaga aaggaggtta gaagagatga
     4801 ttattacaaa aattagccgt ttaggaactt atgtgggagt aaatccacat tttgcaacat
     4861 taatagattt tctagaaaaa acaggactag aaaatttaac agaaggttcg attgctatcg
     4921 atggtaatcg attgtttggg aattgcttta cttatctagc agatggtcaa gcaggggctt
     4981 tctttgaaac ccaccaaaaa tatttggata ttcatttagt tttggaaaac gaagaagcca
     5041 tggctgttac atcgccggaa aatgtaagcg ttacccaaga atatgatgaa gagaaagata
     5101 ttgaattata cacagggaaa gtggaacagt tggttcattt gagagctggc gaatgcctca
     5161 tcacttttcc agaagattta catcaaccca aggttcgtat aaatgatgaa cctgtgaaaa
     5221 aagttgtctt taaagttgcg atttcttaat gtagaaagag aagaacgatg aaaaaaatga
     5281 gaaagttttt atgtctagct ggaattgcgc tagcggctgt tgccttggta gcttgttcag
     5341 gaaaaaaaga agctacaact agtactgaac caccaacaga attatctggt gagattacaa
     5401 tgtggcactc ctttactcaa ggaccccgtt tagaaagtat tcaaaaatca gcagatgctt
     5461 tcatgcaaaa gcatccaaaa acgaaaatca agattgaaac attttcttgg aatgacttct
     5521 atactaaatg gactacaggt ttagcaaatg gaaatgtgcc agatatcagt acagctcttc
     5581 ctaaccaagt aatggaaatg gtcaactcag atgctttggt tccgctaaat gattctatca
     5641 agcgtattgg acaagataaa tttaacgaaa ctgccttaaa tgaagcaaaa atcggagatg
     5701 attactactc tgttcctctt tattcacatg cacaagtcat gtgggttaga acagatttgt
     5761 taaaagaaca taatattgag gttcctaaaa cttgggatca actctatgaa gcttctaaaa
     5821 aattgaaaga agctggagtt tatggcttgt ctgttccgtt tggaacaaat gacttaatgg
     5881 caacacgttt cttgaacttc tacgtacgta gtggtggagg aagcctctta acaaaagatc
     5941 ttaaagcaga cttgacaagc caacttgctc aagatggtat taaatactgg gttaaattgt
     6001 ataaagaaat ctcacctcaa gattctttga actttaatgt ccttcaacaa gctaccttgt
     6061 tctatcaagg aaaaacagca tttgacttta actctggctt ccatatcgga ggaattaatg
     6121 ccaacagtcc tcaattgatt gattcgattg atgcttatcc tattccaaaa atcaaagagt
     6181 ctgataaaga ccaaggaatt gaaacctcaa acattccaat ggttgtttgg aaaaattcaa
     6241 aacatccaga agttgctaaa gcattcttag aagcacttta taatgaagaa gactacgtta
     6301 aattccttga ttcaactcca gtaggtatgt tgccaactat taaggggatt agcgattctg
     6361 cagcctataa agaaaatgaa actcgtaaga aatttaaaca tgctgaagaa gtaattactg
     6421 aagctgttaa aaaaggtact gctattggtt atgaaaatgg gccaagtgta caagctggta
     6481 tgttgactaa ccaacacatt attgaacaaa tgttccaaga tatcattaca aatggaacag
     6541 atcctatgaa agcagcaaaa gaagcagaaa aacaattaaa tgatttattt gaggctgttc
     6601 agtagatgta aaagactaga aaataggtgg gatagtgagc tgaaaagctc tagcccaatc
     6661 ttgtaaaaga agggagaagg agaatggtta aagaacgtaa tttaactcgc tggatatttg
     6721 ttttgccagc tatgattatc gtaggattac tctttgttta tccgtttttc tcgagtattt
     6781 tttatagctt taccaataag catttgatta tgcctaatta taaatttgtt ggtttggcta
     6841 actataaagc tgtgctatca gatcccaact tctttaatgc gttctttaat tcaattaagt
     6901 ggaccgtttt ctcattagtt ggtcaagttt tagtagggtt tgtattggct ttagctcttc
     6961 acagagtacg ccacttcaag aaattatata ggacattatt gattgttcct tgggcatttc
     7021 ctaccatcgt tattgccttc tcttggcagt ggattctaaa cggggtttat ggctacttac
     7081 ctaatctaat cgtaaaatta ggtttaatgg aacatacacc tgcatttttg acagatagta
     7141 catgggcatt cctatgtttg gtgtttatca acatttggtt tggagcacca atgattatgg
     7201 ttaatgtgct ttcagctttg caaacagtac cagaagaaca atttgaggct gctaagatag
     7261 atggtgcttc aagttggcag gtgttcaagt ttatcgtctt tccacatatt aaagtggttg
     7321 taggacttct agttgttttg agaactgtat ggatctttaa taactttgac attatctacc
     7381 tcattactgg tggtggacca gccaatgcta caacgacgct tccaattttt gcttacaacc
     7441 tgggctgggg aactaaattg ttgggtcgtg cttcagcagt tacagtattg ctctttatct
     7501 tcttggtggc gatttgcttt atctactttg ctatcatcag taagtgggaa aaggagggta
     7561 gaaaataatg aagaagaaat ccagtattta tttagatatt ctctcacatg tacttttagt
     7621 tggtgcgacc atcgttgcaa ttttcccatt ggtatggatt atcatatctt ctgtcaaagg
     7681 gaaaggggaa ttaactcagt atccaacacg attttggcct gaacagttta cattagatta
     7741 tttcactcat gttatcaacg atttgcactt cattgataac attcgaaaca gtttaatcat
     7801 tgccttggct acaaccctta ttgcgattat tatttctgct atggcagcct atggtattgt
     7861 tcgattcttt cctaaattgg gagcaatcat gtcgagacta ctcgtcatta cctacatttt
     7921 cccaccaatt ttgttagcaa ttccctattc aattgccatt gctaaagttg ggttaacaaa
     7981 tagtttattt ggcttgatga tggtttatct atcttttagt gttccatatg cagtttggct
     8041 cttagttgga tttttccaaa cagttccaat tggaattgaa gaagcggcta gaattgatgg
     8101 tgcaaataaa tttgttacgt tttataaagt tgtgctaccg attgtagcac caggtattgt
     8161 agcaacagct atttatacat ttatcaatgc ttggaatgaa ttcctgtatg ccttgatttt
     8221 gattaacaat acaggaaaga tgacagtagc agtagccctt cgttcactta atggttcaga
     8281 aatactagac tggggagata tgatggcagc gtctgttatt gtagttcttc catcaattat
     8341 tttcttctct atcatccaaa ataagattgc aagtggatta tcagaaggat ctgtgaagta
     8401 gacgaaagaa ggaaaaaaat gaataaaaga ggtctttatt caaaactagg aatttctgtt
     8461 gtaggcatta gtcttttaat gggagtcccc gctttgattc atgcgaatga attaaactat
     8521 ggtcaactgt ccatatctcc tatttttcaa ggaggttcat atcaactgaa caataagagt
     8581 atagatatca gccctttgtt attagataaa ttgtctggag atagtcagac agtagtaatg
     8641 aaatttaaag cagataaacc aaactctctt caagctttgt ttggcctatc taatagtaaa
     8701 gcaggcttta aaaataatta cttttcaatt ttcatgagag attctggtga gataggtgta
     8761 gaaataagag acgcccaaaa gggaataaat tatttatttt ctagaccagc ttcattatgg
     8821 ggaaagcata aaggacaggc agttgaaaat acactagtat ttgtatctga ttctaaagat
     8881 aaaacataca caatgtatgt taatggaata gaagtgttct ctgaaacagt tgatacattt
     8941 ttgccaattt caaatataaa tggtatagat aaggcaacac taggagctgt taatcgtgaa
     9001 ggtaaggaac attacctcgc aaaaggaagt attgatgaaa tcagtctatt taacaaagca
     9061 attagtgatc aggaagtttc aaatattccc ttgtcaaatc catttcagtt aattttccaa
     9121 tcaggagatt ctactcaagc taactatttt agaataccga cactatatac attaagtagt
     9181 ggaagagttc tatcaagtat tgatgcacgt tatggtggga ctcatgattc taaaagtaag
     9241 attaatattg ccacttctta tagtgatgat aatgggaaaa cgtggagtga gccaattttt
     9301 gctatgaagt ttaatgacta tgaggagcag ttagtttact ggccacgaga taataaatta
     9361 aagaatagtc aaattagtgg aagtgcttca ttcatagatt catccattgt tgaagataaa
     9421 aaatctggga aaacgatatt actagctgat gttatgcctg cgggtattgg aaataataat
     9481 gcaaataaag ccgactcagg ttttaaagaa ataaatggtc attattattt aaaactaaag
     9541 aagaatggag ataacgattt ccgttataca gttagagaaa atggtgtcgt ttatgatgaa
     9601 acaactaata aacctacaaa ttatactata aatgataagt atgaagtttt ggagggagga
     9661 aagtctttaa cagtcgaaca atattcggtt gattttgata gtagctcttt aagagaaagg
     9721 cataatggaa aacaggttcc tatgaatgtt ttctacaaag attcgttatt taaagtgact
     9781 cctactaatt atatagcaat gacaactagt cagaatagag gagagagttg ggaacaattt
     9841 aagttgttgc ctccgttctt aggagaaaaa cataatggaa cttacttgtg tcctggacaa
     9901 ggtttagcat taaaatcaag taacagattg atttttgcaa catatactag tggagaacta
     9961 acctatctca tttctgatga tagtggtcaa acatggaaga aatcctcagc ttcaattccg
    10021 tttaaaaatg caacagcaga agcacaaatg gttgaactga gagatggtgt gattagaaca
    10081 ttctttagaa ccactacagg taagatagct tatatgacta gtagagattc tggagaaaca
    10141 tggtcggaag tttcgtatat tgatggaatt caacaaactt catatggcac acaagtatct
    10201 gcaattaaat actctcaatt aattgatgga aaagaagcag tcattttgag tacaccaaat
    10261 tctagaagtg gccgtaaggg aggtcaatta gttgtcggtt tagtcaataa agaagatgat
    10321 agtattgatt ggaaatacca ctatgatatt gatttgcctt cgtatggtta tgcctattct
    10381 gcgattacag aattgccaaa tcatcacata ggtgtactgt ttgaaaaata tgattcgtgg
    10441 tcgagaaatg aattgcattt aagcaatgta gttcagtata tagatttgga aattaatgat
    10501 ttaacaaaat aaaggagaaa aacatggtta aatacggtgt tgttggagca gggtattttg
    10561 gagctgaatt ggctcgctat atgcaaaaga atgatggagc agagattact cttctctatg
    10621 atccagataa tgcagaggcg attgcagaag aattgggagc aaaagtagca agttccttag
    10681 atgagttggt ttctagcgat gaagtagatt gtgttatcgt cgcaactcca aataatcttc
    10741 ataaggaacc ggttattaag gctgcacagc atggtaaaaa tgttttctgt gaaaaaccaa
    10801 ttgcgctttc ttatcaagat tgtcgcgaga tggtagatgc gtgtaaagaa aacaatgtaa
    10861 cctttatggc aggacatatt atgaatttct ttaatggtgt tcatcatgca aaagaactca
    10921 ttaatcaagg agttatcgga gacgttctat attgtcatac agctcgtaat ggttgggaag
    10981 aacaacaacc gtcagtatca tggaaaaaaa ttcgtgaaaa atcaggtggt cacttgtatc
    11041 accacatcca tgaattggat tgcgttcaat tccttatggg gggcatgcct gaaactgtaa
    11101 ccatgacagg tggaaatgtg gcccatgaag gtgaacattt cggtgatgaa gatgatatga
    11161 tttttgtcaa tatggaattt tctaataagc gttttgcctt gttagaatgg ggttcagctt
    11221 atcgttgggg tgaacattat gtcttaatcc aaggaagcaa aggtgccatc cgcttagact
    11281 tattcaactg taaaggaact cttaagctag atgggcaaga aagctatttc ttgattcacg
    11341 aatcgcaaga agaagatgat gatcggactc gtatctatca tagtacagag atggatggag
    11401 caattgctta tggtaaacca ggtaaacgta ctccattatg gctatcatct gtcattgata
    11461 aagaaatgcg ctatctgcat gagattatgg aaggagctcc agtatcagaa gaatttgcaa
    11521 aacttttgac aggtgaagct gccctagaag caattgctac tgcagatgct tgtacccagt
    11581 ctatgtttga agatcgcaaa gtaaaattgt cagaaattgt aaaataaatt ttggtattct
    11641 cctatttata ggtcgacttg ctcctctgaa agtactttta gaggagctgt ttgactttgc
    11701 tagtttttga aactgaaatc tattatacta caaactattg aaagcgtttt aattttaagg
    11761 tataataatc tcatagaaat aaagaaaagg aggaaagagg atg
//
LOCUS       DBERDS010000053        11591 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.053, whole genome shotgun sequence.
ACCESSION   DBERDS010000053 DBERDS010000000
VERSION     DBERDS010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.053"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            432..1142
                     /gene="deoD"
                     /locus_tag="ACL73E_001740"
     CDS             432..1142
                     /gene="deoD"
                     /locus_tag="ACL73E_001740"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGS0801671.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1165..1689)
                     /locus_tag="ACL73E_001741"
     CDS             complement(1165..1689)
                     /locus_tag="ACL73E_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGS0801672.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1742..1978)
                     /gene="rpsT"
                     /locus_tag="ACL73E_001742"
     CDS             complement(1742..1978)
                     /gene="rpsT"
                     /locus_tag="ACL73E_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGS0801673.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(2046..2966)
                     /gene="coaA"
                     /locus_tag="ACL73E_001743"
     CDS             complement(2046..2966)
                     /gene="coaA"
                     /locus_tag="ACL73E_001743"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGS0801674.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3156..3559
                     /locus_tag="ACL73E_001744"
                     /pseudo
     CDS             3156..3559
                     /locus_tag="ACL73E_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3766..4356
                     /locus_tag="ACL73E_001745"
     CDS             3766..4356
                     /locus_tag="ACL73E_001745"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGS0801675.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4353..5630
                     /locus_tag="ACL73E_001746"
     CDS             4353..5630
                     /locus_tag="ACL73E_001746"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGS0801676.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5648..6310
                     /gene="deoC"
                     /locus_tag="ACL73E_001747"
     CDS             5648..6310
                     /gene="deoC"
                     /locus_tag="ACL73E_001747"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGS0801677.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6297..6686
                     /locus_tag="ACL73E_001748"
     CDS             6297..6686
                     /locus_tag="ACL73E_001748"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS0801678.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6777..7829
                     /locus_tag="ACL73E_001749"
     CDS             6777..7829
                     /locus_tag="ACL73E_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGS0801679.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7973..9508
                     /locus_tag="ACL73E_001750"
     CDS             7973..9508
                     /locus_tag="ACL73E_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801680.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9501..10559
                     /locus_tag="ACL73E_001751"
     CDS             9501..10559
                     /locus_tag="ACL73E_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801681.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10562..11518
                     /locus_tag="ACL73E_001752"
     CDS             10562..11518
                     /locus_tag="ACL73E_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801682.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3304 a         2075 c         2653 g         3559 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa aggaattgac cccaccctaa
      181 aagtagtggg aaaaagatag ttggtctagc gagcatcgct cactgcgccc aactcctatt
      241 ttcccttcgc tttttgatgg gtttggtatc tttctcaata taaaatataa aataaagaaa
      301 ggtagagcgt gtgttttgat ttgaacacga gcggaaaact cggaaaatag ataatctgac
      361 tgaaaaatca ggatttctcg tcaggttcct aattttcagt cgttttcttc tcgctctttg
      421 tatcataaat tatgtctatc catattgctg ctcagcaggg tgaaattgct gataaaattc
      481 ttcttcctgg ggatcctctt cgtgctaagt ttattgcgga gaatttcctt ggtgatgctg
      541 tttgttttaa cgaagtgcgt aacatgtttg gttacactgg tacttacaag ggtcaccgtg
      601 tatctgtcat gggaactggg atgggaatgc catctatttc gatttatgcg cgtgagttaa
      661 tcgtagacta cggtgtgaag aaattgattc gtgtgggaac tgcaggttct ttgaatgaag
      721 aggttcatgt tcgtgaatta gttttggcgc aggcggctgc aaccaactca aacatcgttc
      781 gtaatgactg gccacagtac gattttccac aaattgctag ctttgatttg cttgataaag
      841 cctaccatat cgccaaagaa cttggtatga ctactcacgt tgggaacgtt ttgtcatctg
      901 atgtctttta ctcaaattac tttgaaaaga atatcgagct tggtaaatgg ggagtcaagg
      961 ctgtggaaat ggaagcagca gctctttact atcttgctgc ccaataccat gttgatgcgc
     1021 tagctatcat gaccatctct gatagcttgg tcaatccaga cgaagacaca actgcagaag
     1081 aacgtcaaaa taccttcact gatatgatga aggttggttt ggaaaccttg attgcagaat
     1141 aattatagcc aaaaaggaag ccctttatga attgtaggac ttccttttct tatccagaaa
     1201 ttgatctagc tctctctgat ttcgaagaat agtgacttta tgtgaatatt cttggcaaag
     1261 tttttggtaa ttttcttttt gagttttgct acgcccatcc caaagaatcc atctgataaa
     1321 ctcccagtca aagcgttcag ggcaatctgc cgccatactt tctctgactt ttccacggta
     1381 tttaagataa cgcttaaagg ctctaaagag acaggtcaat ggcaaaaaat tgagaaagat
     1441 gatttggtca gcttcttgca ttcgttcttg gtagtagcac caagaataat taccatcgat
     1501 gacccaagct ttatgcttgg tgagaaagtt ttttatctcg gttaacatcc attcgcagtc
     1561 actgtcttgc caaccaggtt gaaattggag tgtgtccatg tgcagttttg gaatggagta
     1621 gtagttagat aacttttctg ctagagttga cttaccagaa ccagaatatc cgataattgt
     1681 gattttcatt ttctaccttt tcctatttgg agacaaaaaa acagcctcta tggactgttt
     1741 cttatttagc aagtttagtt gaaagacgag ctttatcgcg gcttgctttg tttttgtgaa
     1801 tcaaaccttt agtttctgct ttatcgatag ctgagctagc agcacggaaa agttcttcag
     1861 atgggtttgc ttcgaaagct tttatagcag tacgcatagc tgatttttga gctgagttct
     1921 tttcgttttg tttaacgttc aattcagcgc gtttgatagc tgatttaatg tttgccaatg
     1981 ttcttacctc catatttact aactatacca ttatatatga aaacttacgt tttgacaagg
     2041 gaaaattact tttttaagta aatttcatcg atttcatggt tcttgctttt atgaagaatc
     2101 acttctgcac gatttctggt tggttcaata taattttgca gatttgtgag attgatactg
     2161 atccagacct gatgggcaaa ggactccact tccccaatcg gcatctgagt aaaacgataa
     2221 tagtagctat cagggtcgtt ttgggctagg ctcagcatct tcaagaaacg gtccagatac
     2281 caactttcaa tatcatccac tccagcatct acatagatgg aaaagtcaaa gaagtcagtg
     2341 atatagagac gatcgttttg tggattttga aagacattaa ttccctcaac aattacaaaa
     2401 tcagcagctt tgacactttg tttcttttcg ggtacgatgt cgtaaacttc atgagaatag
     2461 acaggaatat ctacatcttg tccatttttg atgcggtcca agaagttgag aagagcttcc
     2521 atatcatagc tttcaggaaa tcctttacga tttaaaatcc cctgctcaat caaggtttga
     2581 ttgggataga gaaaaccatc agttgtaacc aactcaaccg tagcatctgt aaacgtacgg
     2641 gacagtagga tttgaagtag gcgactggtt gtggattttc caacggcaac actcccagaa
     2701 accccaataa taaaaggttg agatttactt tcacgttgga ggaaaattcc ttttgaaaag
     2761 gctaaatctt ccttagttcg cttgtaaatc tgaatcagat gagccaaggg gagatagata
     2821 tctgtaacgt cttggagact gatttggtca ttaaaactct tgatagattc caattcttct
     2881 tctgtcaaag gaggtgttgt ctttcgatgt aaagattgcc aagtctggcg gctgattttt
     2941 tcaaaatgta aaaattcgtt ggtcatttgt tttcccctag atattttgtc tatcatacca
     3001 taaaaagcta aaaaaataaa gcggtttctt gaatgtggta agtcaatggt atatagtata
     3061 agtgatcaat ttattgatga aataggagat agattctact gatttataag cttataaagg
     3121 gggcttttta gttcacaact tataggaggt gtactatgaa aatcttaaaa cgttacatat
     3181 tggaactctg ttttatttta agttttgctt taccttttat aaaaggaacc aatgcagata
     3241 atggtagatg ctttgtggaa acctattacg gttttacttt tttgatggaa catgctattg
     3301 taacagctgt ctttatctgt tcgttcttaa ttgctttctt actaaaaaac gatggacgaa
     3361 atggattgct gcgggtagtt attgcttttt agtcctacgg attgcgacag agggttattt
     3421 cttccacatg tcactagaag atttgatacg actttggaca agtttggaaa tcctgacaca
     3481 aacgtatcag ttgggctttt atctaaacat tttgttagga attttgttga taataaagta
     3541 ttttaaggtt aagcaataga aataataatc tgcctgatta tagatgataa actttttgtt
     3601 tttatctgga ctgtgatatt tatagttcta aatggtttat tatttataag tgttgaaaga
     3661 gattgaagaa aatggcttcg tgacttgctt tcttcggtct ttttcgtttt attatcaatt
     3721 tgtaaacgat ttacaatttg agtcaaatta tggtaaaata gtgtcatgag taaaatgtac
     3781 tatgcagaaa atcctgacgc tgctcacgac attcatgagt tgagagtgga cttgttggga
     3841 gaaaaaatga cttttttgac agatgcgggt gtttttagca agaaaatggt tgactttgga
     3901 agtcaactct tgctcaagtg tctggatgtc aaccaaggag agacagtcct agatgtaggc
     3961 tgtggttatg gtccattagg tttgtccttg gtcaaggttt acggagttca ggcgaccatg
     4021 gttgatatta acactcgtgc cctggattta gctcagagaa atgctgaaaa aaataatgca
     4081 aaagcgacga tatttcaatc taatatttat gcaagagttc aagggcgatt tgaccatgtc
     4141 atttccaatc ctcctatccg tgcgggcaag caagtcgttc atgaaatcat cgagaaaagt
     4201 aaagatttct tggaaattgg tggagatttg accatcgtca tccagaaaaa acaaggagct
     4261 ccaagtgcca aatctaagat ggaagatgtg tttggcaatt gtgaaatcct taaaaaagac
     4321 aagggatact atatccttag aagtgtgaaa gaatgagagc agttgattta atccaaaaaa
     4381 aacgagacgg tcaagaactg acttcaagtg aaattgaatg gctgatagaa ggctatgtat
     4441 caggaactgt tcctgattat cagatgtctg cctttgctat ggctgtttat tttaaaggaa
     4501 tgacgactcg agaaatctct gatttaacga tgaatatggt taagactggg caagagtttg
     4561 acctgtcagc cattgatggt gtgaaagttg acaagcattc tactggtggt gtcggcgata
     4621 aggtaacctt gattttagct cctcttgttg ctagcttcgg tgtgcctgta gcaaaaatga
     4681 gtggtcgtgg tcttggccat acaggcggaa caattgataa attggagtcc attaggggct
     4741 atcaagtaga acgtagtcaa gaggatttta ttcgtcaggt tcaggatatt ggagtatctg
     4801 tcattgggca atcagaccag ctggtcaaag cagataagct tctctatgcc cttcgtgatg
     4861 tgaccgcaac tgtcgacacg attcctttga ttgcgagttc ggtgatgagc aagaaaattg
     4921 cggcaggggc ggatgctatt ttgctagacg tgactgtcgg tgagggtgcc ttcatgaaga
     4981 cggttgatga ggcgcgtgag ttggctcaaa ctatggtaga tcttggtaag gttgttggac
     5041 ggaagacagt agcagtgatt acggatatga gccagccttt gggacgagcg attggaaatc
     5101 gtctggaaat ccttgaagca ttggagattt tgcaaggtca aggacgtcag gatattaccc
     5161 actttatttg tgaattggct caaattatgc ttggtttggc aaatgttaac aaaactgttg
     5221 aagaagttcg ccaacatctt gaaaatggtc aagcactggc taagtttgag gaaatggtgc
     5281 aagcccaagg tggagacttg gaagacctct atcgtcctgt aaatgtagct catgtggtgg
     5341 aaatccctgc tcaggaaacg ggtgtcattt cagctcttcc agctatggac tttggtcttt
     5401 atgccatgag gctgggtgct ggtcgtgcag ttaagtctga tgtcttggac tatgaaacag
     5461 gaattgtttt tgaaaagaag attggagact ccgttcaaaa gggtgaaatt gttgcaaaag
     5521 tatacacaaa tgaaaaaatt ccacctcaac tagttacaga tttccaaaaa tgtgttaaaa
     5581 taagtgatga agtgaaaaaa atccgtgaaa ttgtagaaat catctcctaa atggagggaa
     5641 aaccgaaatg aaattaaata aatatataga tcatacgctt ttaaaacaag atgcaaagaa
     5701 aaaacaaatt gatagtttgt tgtctgaggc tagagagtat ggctttgcca gtgtttgcgt
     5761 taatccgacc tgggttgaac atgctaaaaa aggacttgaa ggcacagatg ttaaggtttg
     5821 cacagtagta ggtttcccct tgggagcaac aacttcaact gtgaaagctt ttgaaacaaa
     5881 agaagctatc caaaatgggg ctgatgagat tgacatggta atcaatgttg gggctctcaa
     5941 gtcaggtgat ttggccttgg ttgagtcgga tattcgtgca gtagtggaag caagtgggga
     6001 caagttagtg aaagttatta ttgaagcttg ccttctgaca gaccaagaaa aagttttggc
     6061 ttgccaatta gcccaaaaag caggagctga ctttgtcaaa acatctactg gcttttcaac
     6121 tggtggtgct acgatagcag atgttagatt aatgcgtgaa acagttggac ctgatatggg
     6181 tgtcaaggcc gccggtggag ctcgttctta tgcagatgct cttacctttg tcgaagcagg
     6241 tgcgacccgt atcggaacgt cagctggggt agctatttta aaaggagaat tggcagatgg
     6301 cgactactga gttgattgaa ctggcaattg aaaccagcaa acatgcctat gtcccctatt
     6361 ctcactttcc tatcggagca gttttagtag ccaaagacgg aagtgtttac acgggagtga
     6421 atatcgaaaa tgctagctat cctttgacca attgcggtga gagaacagct atttttaagg
     6481 ctatatctga aggccaaaga gaattttcag aattgattgt ctatggtcaa actgaaaaac
     6541 cgatttcacc atgtggtgct tgtcgccaag taatggtcga attttttgaa caagatttaa
     6601 aagtgaccct agtcgcaaaa gataaatcga cggtcgagat gacggtcggg gagttacttc
     6661 catactcttt tacagactta aattagtctg agtcgctctt tgagtggcaa gggtctttgt
     6721 gaccaatcaa tccatacttg caacatcgtt gcacatctta tttaggaggt tcagtaatga
     6781 acaagaaaca atggctaggt cttggcctag ttgcagtggc agcagttgga cttgctgcat
     6841 gtggtaaccg ctcttctcgt aacgcagctt catcttctga tgtgaagaca aaagcagcaa
     6901 tcgtcactga tactggtggt gttgatgaca aatcattcaa ccaatcagct tgggaaggtt
     6961 tgcaagactg gggtaaagaa cacaatcttt caaaagataa cggtttcact tacttccaat
     7021 caacaagtga agctgactac gctaacaact tgcaacaagc ggctggaagt tacaacctaa
     7081 tctttggtgt tggttttgcc cttcacaatg cagttgaaga agcagctaaa gaacacactg
     7141 acttgaacta tgtcttgatt gatgatgtga ttaaagacca aaaaaatgtt gcgagcgtaa
     7201 ctttcgctga taatgagtca ggttaccttg caggtgtggc tgcagcaaaa acaactaaga
     7261 caaaacaagt tggttttgta ggtggtatcg aatctgaagt tatctctcgt tttgaggcag
     7321 gattcaaggc tggtgttgcg tcagtagacc catctatcaa agtacaagtt gactacgctg
     7381 gttcatttgg tgatgcggct aaaggtaaaa caattgcagc cgcacaatac gcagccggtg
     7441 cagatattgt ttaccaagta gctggtggta caggtgcagg tgtctttgca gaggcaaaat
     7501 ctctcaacga aagccgtcct gaaaatgaaa aagtttgggt tatcggtgtt gaccgtgacc
     7561 aagaagcaga aggtaaatac acttctaaag atggcaaaga atcaaacttt gttcttgtat
     7621 ctactttgaa acaagttggt acaactgtaa aagatatttc taacaaggca gaaaaaggag
     7681 aattccctgg cggtcaagtg atcgtttact cattgaagga taaaggggtt gacttggcag
     7741 taacaaacct ttcagaagaa ggtaaaaaag ctgtcgaaga tgcaaaagct aaaatccttg
     7801 atggaagcgt aaaagttcct gaaaaataat ggatggaagt catttcttag gaagcggcca
     7861 agggccgctt ttttaagagt tgagacaaag tcattttgtc tcagtaaagc ttgctactag
     7921 acaaactagc aagttttatt gaaataaaat aagactctga aaggaagagc acatggcaca
     7981 cgaaaatgtc attgagatgc gtgatattac caaggtgttt ggtggatttg ttgccaacga
     8041 caaaatcaac ttgcacctac gaaaaggtga aattcatgca cttttaggag aaaatggggc
     8101 tggtaagtcc acgctaatga acatgttagc aggccttctt gaaccaacca gtggtgaaat
     8161 cgcggtcaac ggtcaagttg tcaatctcga ctccccatct aaagcagcta gcttgggaat
     8221 cgggatggtt caccagcact ttatgttggt tgaagccttc acagtggctg aaaacatcat
     8281 tttaggtagt gaattgacta aaaatggtgt gctagatatc gctggagcta gcaaagaaat
     8341 caaggctctt tctgaacgtt atggcttagc tgttgaccct tctgccaagg tagcagatat
     8401 ctcagttgga gcccaacaac gtgtagaaat tttaaaaaca ctttatcggg gggctgatat
     8461 ccttatcttt gacgaaccaa cggctgtttt gactccatca gaaattgatg agttgatggc
     8521 tattatgaaa aatcttgtca aagaaggaaa atcaattatc ttgattaccc acaaattgga
     8581 tgaaattcgc gcagtttctg accgtgttac agttatccgt cgtgggaaat caattgaaac
     8641 cgttgaaatt gcaggggcta ccaatgctga tttggcggaa atgatggtag gacgttctgt
     8701 ttcctttaaa acagagaagc aagcctctaa accaaaagaa gtggttttgt ctatcaaaga
     8761 tttggtggtc aatgaaaacc gtggtgttcc agctgttaaa aatctgtcct tggatgttcg
     8821 tgctggagag attgttggta ttgcggggat tgatggaaat ggtcagtctg aactgattca
     8881 agccattaca ggtcttcgta aggttgaatc tggtagcatt gagctaaaag gagattcaat
     8941 tgtaggcttg cacccacgtc agattacaga actaagtgtt gggcacgttc cagaagaccg
     9001 tcaccgtgat ggcttgattt tggaaatgat gatatctgaa aatattgccc ttcaaaccta
     9061 ctataaagaa ccacatagta aaaatggaat tttgaattat tcaaatatta cttcttatgc
     9121 taaaaagctg atggaagagt ttgatgttcg cgctgccagt gaattagttc ctgcagctgc
     9181 actctcagga ggaaatcaac aaaaagcaat tattgctcgt gaaattgatc gagatcctga
     9241 tctccttatc gttagccagc caactcgtgg gttggatgtc ggtgccattg agtatatcca
     9301 caaacgcttg attgaagagc gtgataatgg caaggctgtc cttgttgtca gctttgaatt
     9361 ggatgagatt ttaaacgtct cagaccgtat tgccgttatc cacgatggta agattcaagg
     9421 tattgtatca ccagaaacaa ccaataaaca aggacttggt gtcttgatgg ctggtggaaa
     9481 cttgggaaag gagaagagtg atgtctaaaa aattacaaca aatttcggtt cccttgattt
     9541 ctgtattcct aggaatttta ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta
     9601 tttggggcta cgaagaattg ttctatacag cctttggcag tctgcgtggg attggagaaa
     9661 tcttccgtgc tatgggtcct ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag
     9721 ctggtttctt taacgtcgga cttcctggtc aggctttggc aggttggatt ctcagtggtt
     9781 ggtttgccct gtcgcatcca gatatgcccc gtcccttgat gattctagca accatcgtga
     9841 ttgccttgat tgctggtggg attgtcggag cgattccagg tattcttagg gcctatctag
     9901 ggacgtcaga ggttattgta accatcatga tgaactacat tgtcttgtat gtagggaatg
     9961 cctttatcca tgctttccct aaagacttca tgcaaagtac agattcgacc attcgtgttg
    10021 gggctaatgc aacctatcag acaccttggt tagctgagtt gactggtaac tcacggatga
    10081 atattggtat tttctttgcc atcattgccg ttgcagttat ttggttcatg ctcaagaaaa
    10141 caactcttgg ttttgaaatc cgtgcagttg gtcttaatcc acatgcttca gaatatgctg
    10201 gtatttctgc caagcggact attatcctat ctatgattat ttcaggtgcc ttggcaggtc
    10261 ttggtggagc tgttgaaggt ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat
    10321 tagctatcgg atttaacgga atggcggtta gtttgcttgc ggccaactca ccaattggta
    10381 tactctttgc agccttccta tttggcgttc tccaagttgg ggctcctggt atgaatgcgg
    10441 cgcaggtacc atctgagctt gtcagcattg taacagcgtc tattatcttc tttgtcagtg
    10501 ttcattacct tatcgaacgc tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa
    10561 gatgtctatt ataaccttgc tccccctctt ggtgtcttct atgctgattt actcagcacc
    10621 tctcatcttt acaagtatcg gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg
    10681 ccttgaagga attatggtta tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc
    10741 agaacaattt ggagcagcaa ctccatggct atccttgctt gtagcaggat tggttggtag
    10801 tgttttctct atcatccacg cagcagcgac ggttcatttc cgtgcagacc atgttgtcag
    10861 cggtacggta ttgaacttga tggcgcctgc cttggctgtt ttcttagtta aagttcttta
    10921 taacaaagga caaaccgaca acctaagtca aacttttgga cgctttgatt tcccagtctt
    10981 ggcaaatatc ccagtgattg gtgatatctt cttcaagtca actagtctac ttggttatct
    11041 ggcgattgcc ttctcattcc ttgcttggtt tattctcttt aagactcaat ttggtcttcg
    11101 tctccgctct gtcggtgaac atcctcaagc agcggatacc ttgggaatca acgtctacaa
    11161 gatgagatat ttaggggtta ttatttcagg ttttctaggt ggaattggcg gagcgattta
    11221 tgcgcaatca atctcagtta acttctcagt gacaactatt gttggacctg gatttatcgc
    11281 ccttgctgcg atgatctttg ggaaatggaa tccaatcggt gctatgcttt ctagtctctt
    11341 ctttggactt tcacaaagtt tggctgttat cggttctcaa ttgccgttcc tacaaggagt
    11401 gccagcggtt tatcttcaaa ttgcacctta tgttttgaca attcttgtct tagcagcctt
    11461 ctttggaaaa gcagtcgcac caaaagcaga tggtatcaac tacatcaaat caaaataagc
    11521 atacaaaaaa acgtcagtcc aatgactgaa ctgcccccca aaagttagac agaaaaaatc
    11581 taacttttgg g
//
LOCUS       DBERDS010000054        11013 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.054, whole genome shotgun sequence.
ACCESSION   DBERDS010000054 DBERDS010000000
VERSION     DBERDS010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.054"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            31..753
                     /locus_tag="ACL73E_001753"
     CDS             31..753
                     /locus_tag="ACL73E_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGS0801683.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            750..1598
                     /locus_tag="ACL73E_001754"
     CDS             750..1598
                     /locus_tag="ACL73E_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGS0801684.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            1630..2559
                     /gene="psaA"
                     /locus_tag="ACL73E_001755"
     CDS             1630..2559
                     /gene="psaA"
                     /locus_tag="ACL73E_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGS0801685.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEANLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            2682..3173
                     /gene="tpx"
                     /locus_tag="ACL73E_001756"
     CDS             2682..3173
                     /gene="tpx"
                     /locus_tag="ACL73E_001756"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGS0801686.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(3269..5977)
                     /locus_tag="ACL73E_001757"
     CDS             complement(3269..5977)
                     /locus_tag="ACL73E_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS0801687.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALTTHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLRLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVVAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(5979..6680)
                     /locus_tag="ACL73E_001758"
     CDS             complement(5979..6680)
                     /locus_tag="ACL73E_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801688.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            complement(6930..9341)
                     /locus_tag="ACL73E_001759"
     CDS             complement(6930..9341)
                     /locus_tag="ACL73E_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGS0801689.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            complement(9394..10086)
                     /locus_tag="ACL73E_001760"
     CDS             complement(9394..10086)
                     /locus_tag="ACL73E_001760"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGS0801690.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(10621..11006)
                     /locus_tag="ACL73E_001761"
                     /pseudo
     CDS             complement(10621..11006)
                     /locus_tag="ACL73E_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3227 a         2522 c         2055 g         3209 t
ORIGIN      
        1 tatattaaga gacaggagga atataagttt atgatacgta tcgaaaacct cagtgtctcc
       61 tacaaagaaa cgttggcact taaggatatt tcactagtgc tccatggacc aacaattacc
      121 ggcatcattg gtccaaacgg cgctgggaaa tcaacactat taaaaggtat gttgggaatt
      181 atcccacatc aaggtcaggc atttctcgat gacaaggaag ttaaaaaatc cttacaccga
      241 attgcctatg tcgaacaaaa aatcaatatc gactacaact ttcccatcaa ggtcaaggaa
      301 tgcgtctcgt taggactatt tccctctatt cctctctttc gaagtttaaa ggctaaacat
      361 tggaagaaag tgcaagaggc ccttgaaatc gtcggcctag ctgactacgc tgaacgtcaa
      421 attagtcaac tgtctggagg tcaattccag cgggtcttga ttgccagatg tttggtgcag
      481 gaagccgact atatcctctt ggatgaaccc tttgctggga ttgactctgt cagtgaggaa
      541 atcatcatga atacgctgag agatttgaaa aaagctggga agacggttct catcgttcac
      601 cacgacctca gcaagattcc ccactacttc gatcaagtct tacttgtcaa tcgagaagtg
      661 attgcctttg gtccaacaaa agaaactttt accgaaacca atctaaaaga agcttacggt
      721 aatcaactct ttttcaatgg aggtgaccta tgattgcaga atttatcgat ggattgcaaa
      781 aattccattt cctacaaaat gccttgataa cagctattgt cgtcgggatt gtagctggag
      841 ctgtgggatg tttcattatt ctacgcggga tgtcactcat gggagatgcc atttcacatg
      901 ctgtcttacc aggtgtagcc ctatccttca tcttgggcct tgacttcttt atcggagcca
      961 ttgtctttgg attgctagct gccatcatca ttacctacat caaaggaaac tcgattatca
     1021 aaagcgatac cgccatcggc attacctttt cttctttctt agccctcggt atcatcttga
     1081 ttggtgtcgc taaaagttca actgaccttt tccatatcct ttttggtaat atcctggccg
     1141 tccaagatac ggatatgttt attactatgg gtgtgggggc agctatcctc ttgttaatct
     1201 ggattttctt caagcaactc ttgataactt cctttgatga actcttggct aaagccatgg
     1261 gaatgcctgt caatttctat cactaccttc tcatggtact cctgactctc gtgtctgtga
     1321 cagccatgca aagtgtcgga actatcctga ttgtagccat gctgattacc ccagctgcaa
     1381 ctgcttatct gtatgctaat agtctgaaaa gtatgatttt cctttcctca accttcggag
     1441 ctactgcttc agttttggga ctctttattg gctatagttt taatgttgcg gcaggttcta
     1501 gtatcgtgct tacagctgct agtttctttc tcattagctt ctttatcgct cccaaacaac
     1561 gatatttgaa actgaaaaat aaacatttgt taaaataagg ggcaaagccc taataaattg
     1621 gaggatctaa tgaaaaaatt aggtacatta ctcgttctct ttctttctgc aatcattctt
     1681 gtagcatgtg ctagcggaaa aaaagataca acttctggtc aaaaactaaa agttgttgct
     1741 acaaactcaa tcatcgctga tattactaaa aatattgctg gtgacaaaat tgaccttcat
     1801 agtatcgttc cgattgggca agacccacac gaatacgaac cacttcctga agacgttaag
     1861 aaaacttctg aggctaattt gattttctat aacggtatca accttgaaac aggtggcaat
     1921 gcttggttta caaaattggt agaaaatgcc aagaaaactg aaaacaaaga ctacttcgca
     1981 gtcagcgacg gcgttgatgt tatctacctt gaaggtcaaa atgaaaaagg aaaagaagac
     2041 ccacacgctt ggcttaacct tgaaaacggt attatttttg ctaaaaatat cgccaaacaa
     2101 ttgagcgcca aagaccctaa caataaagaa ttctatgaaa aaaatctcaa agaatatact
     2161 gataagttag acaaacttga taaagaaagt aaggataaat ttaataagat ccctgctgaa
     2221 aagaaactca ttgtaaccag cgaaggagca ttcaaatact tctctaaagc ctatggtgtc
     2281 ccaagtgctt acatctggga aatcaatact gaagaagaag gaactcctga acaaatcaag
     2341 accttggttg aaaaacttcg ccaaacaaaa gttccatcac tctttgtaga atcaagtgtg
     2401 gatgaccgtc caatgaaaac tgtttctcaa gacacaaaca tcccaatcta cgctcaaatc
     2461 tttactgact ctatcgcaga acaaggtaaa gaaggcgaca gctactacag catgatgaaa
     2521 tacaaccttg acaagattgc tgaaggattg gcaaaataaa cctatgaaaa acgtcattct
     2581 cacatgagct ggcgtttttt ctatgcccat atttccggtc aaatcattgg aaaattccga
     2641 ctgtttcagc taaaatggaa gaaaaaagat tggagtatcc tatggtaact tttctcggaa
     2701 atcctgtgag ctttacaggt aaacaactac aagtcggcga caaggcgctt gatttttctc
     2761 ttactacaac agatctttct aaaaaatctc tggctgattt tgatggcaag aaaaaagtct
     2821 tgagtgtcgt tccttctatc gatacaggca tctgctcaac tcaaacacgt cgttttaatg
     2881 aagaattggc tggactggac aacacggtcg tattgactgt ttcaatggac ctaccttttg
     2941 ctcaaaaacg ttggtgcggt gctgaaggcc ttgacaatgc cattatgctt tcagactact
     3001 ttgaccattc tttcgggcgc gattatgccc tcttgatcaa cgaatggcac ctattagcac
     3061 gcgcagtctt tgtcctcgat actgacaata cgattcgcta cgttgaatac gtggataata
     3121 tcaattctga gccaaacttc gaagccgcaa ttgcagctgc taaagcccta tagaaaaaat
     3181 cctctgtcac aaagagttcc ctgctctttg aaacggagga tttttgaata ttagtaaata
     3241 gaagttcaat cagctaaaaa taactacctt actctacaga tttcagggct tctaacatat
     3301 caacctttct cagataataa ttgacgaaga aaccaagcaa ggtcaaaatg atgcttactg
     3361 ctgccactgg gattacatag acttcccagc ctacctgcgg ataaaagaga atagtcgcag
     3421 gcgaaatcat ttgaatcaaa aattggtgta aatagaaacc agctatcaga ccaagtacga
     3481 ttcccacaag ggacagcaca atcgtctcac ggtaaatgta gagggtgact tcattattat
     3541 gaaaaccaag aaccttgata gtggagagtt cacggattct ctcagctacg ttgatattgg
     3601 tcagattgta aaggatgaca atagctaata gaaccgatac gatgaccaag atggtcatgg
     3661 tctgattgag tgagctagcg atagagtcga agagtcgaat ggctgaagca ttttggacaa
     3721 cgctggacac cgcagattga ttcataagca agcccgcctg actttcgata ctagttgcac
     3781 tggtatccct taatgagacc agataagtgt tggcttgggg tagctgtccg taaagttgct
     3841 catagctagc ctgactcata taaataaagt gaccaacgta gttctcagta atagcaacga
     3901 cctttagttc cttaccttca atttctaaag tctgcccaac cttgacacct gccagctggg
     3961 cgagtttagc tgtaataacg atgccatctt ttaatgtcag ctcctgctga tgatgttgaa
     4021 gatggataaa gggagtcaaa tcttccttct ctatcatcat aagagtaatg ttttgaagac
     4081 cagctttgcc tttgaaatcc ttgtatagcg ctttagaata gattttctgg taggctagta
     4141 tctcctgccc tttcaacact tctgctagct ctaccttgtc ctgattggtc gcactaggat
     4201 tttcagagac aagcatctga tactgttgga tttgttgaaa ctgtttagac ggaactcctg
     4261 ctacagaaga ttggattccc aaacctgcaa agagcagagc tacagaacct gccacaccaa
     4321 agattgtcat caacattctc tgcttataac gaaagatgtt gcgggctgtt accttatgag
     4381 taaaactgag acgacgccag ataaaaccga tacgctccaa taagatttta gctcctttga
     4441 caggaggttt aggaagtaga agctgggctg cttcgtcatg aagttccctc caagccacca
     4501 gataggctgg taacacactc gccaacaagc tcaagacaaa agctagtaag ctataggtcc
     4561 aatagaactg aatctgagtt tctcccacca ccatgccttt tgtaatgaca cttgaaatta
     4621 cactggctag caaataatga ccaagtatac tacctagagc cgttccgaca gtcccagcta
     4681 ctagtccata aaggagaaac ttggcgataa tatccttact acgataaccc aaggccttaa
     4741 aaatccctgc atgagttcgc tcttcgtcta caaagcgagt catggtcgta aaggtcacca
     4801 tggctgctac ggcataaagt accacaggaa agatattgcc cactgctcga atactggatg
     4861 aagcattgct atacataaga tagccctgac cacctggcat ggtctgacga ttataaacct
     4921 gataccttgg ctccgccaaa tcatccaaga cttgctgatg tttttctaat ttttcctttt
     4981 cttgggctag attttgttca gcttgcttta gtttgtcctc ttccttgccc aattcctgct
     5041 tggcttgggt aagttgagca ctagcctgct ctctctgagc ttgaggaaac aaggctagtt
     5101 gactttcttg agcctgtata cgagcttgag cagctgctaa acgacgcttg ccttcctgca
     5161 aattagtctg agccttgtca agggtctctt gccccttgtc tagagactct tgtccttctt
     5221 ttttcaaaag tcgcagacgt accttgccat tatctgataa aatttgttca agctcttcct
     5281 gatgttgctt ggatttttct tcataagctg atgaaaaggc atttaaacct gctaaatctt
     5341 gatatttcaa acgagctata ttgtagactt tctgatcaaa ttgactaggt aaaatcaccc
     5401 cataggctgt cagagtccca cttccacttc ctgcgtagcc catatctcgc tgggagagga
     5461 tttcagccga atccacaaaa ccagtaatgg tataagtatg gtcttttaaa gaggaatgac
     5521 cctcttcttt ttctttaaaa ctaatctcct gtcccacgct gtattggcct tgcaaatgag
     5581 tggtcaaagc gatttccttg tctgactgag gaagtcgtcc ctttcttagc tgaaaggttg
     5641 aaattcgctc tggtttggag tacagccgaa tggcatcctg cccattatcc atagtcacat
     5701 ctgtcaaata gccaaactcg acctctgcgc cctccgtctg ttttagttct tcttggtctg
     5761 cttgatccaa gccatagtta gacatgactg ccaaatctaa ggtttgagca gttgttaaat
     5821 aagcattagc tgtcgcctcc atgttgggac tggttacttt gaggcctact aaggctagag
     5881 atcccaacat catcaggatc aagatggata aaaaacgccc cttggagcct gtgaaggact
     5941 gaattaagtc cttccaataa gtttttcgct tgatcatgct agtactccaa actgtcaata
     6001 tcctgaggat gctggttgag caccacatcc ttgacactgg catcgtgcat atgaatcacg
     6061 cgatcagcaa tgggcgccaa agctccatta tgagtcacaa tgatcaccgt cgctcccttt
     6121 tgacgagaca tgtcttggag aattttcaaa acctgcttgc ccgtctgata atccaaggct
     6181 ccagtcggtt catcacaaag gagaatttta ggatttttgg ctaccgcgcg tgcaatggag
     6241 actcgctgtt gctcccctcc agaaagctgg gctggaaagt tatttagacg atgagccaga
     6301 cctacatctg tcaagacctg atcaggattc aaggcatctg tcacaatttc agaagccagt
     6361 tccacatttt ccttagctgt cagattagaa actagattat aaaactgaaa aacaaacccc
     6421 acatcatttc tacggtaatt ggtgcgctgg tgggaactat aatccgcaat attaacacca
     6481 tcaatccaga tttccccttc atcattggta tccattcccc caagaaggtt aagaactgtt
     6541 gacttgcctg cacctgaagc accaaggata ataaccagct cccccttttc aatctcaaaa
     6601 ttcacatcac gattagccac aatctccgtg tccccaacct gataacgctt gtaacagtgt
     6661 ttcatctcaa tataagccat cagacccacc ctctatcaaa caaattatac tcctcgaaaa
     6721 tctctcttca aaccacgtca gcttccatct gcaacctcaa aacactgttt tgagcaacct
     6781 gcggctagct tccttgtttg tgctctttga ttttcattga gtattacttc ctattatcat
     6841 tataacgctt tttcaactag ttgaaaactg cttatattct taaatcctta ttaaaaggca
     6901 gtttcaaatt actgccttat aacatcttct taaaaataaa attgaacaag atcaccttct
     6961 gctgttgcca ccgaaataca atctttcccc atgcatttcg cttttatttt ttcttgattc
     7021 attttaatca cactcttctc aatatctgga taagaaactc gcaaatctcc tccgctcctt
     7081 gataaaatgg tcaactgtaa gagtttttta tcttcccagc tcatgctcac ttcaaaatgt
     7141 ccacgtgcca ttaagcctga aacagaacct gttgaccaag catcaggtag ggcagctaga
     7201 ggtaccagat aagctgcatg agactggagt aacatttctg ccatgccact agtagcacca
     7261 aaattaccat ctatctgaaa aggaggatgg ctacaccaaa gatttggcaa ggtggatgtc
     7321 tttaactgct ctgccaataa tttatgggcg cgattgccat ctcccaaacg cgcccagaga
     7381 ttgatcttat tagccttgga ccagcctgtg ccgccatctc cacgatcatt gaggctagca
     7441 cgcgccgctt caatatactc ttgtcccttg tagctaaaga gattgccagg atagagtccc
     7501 actagatggg aagcgtgccg gtgctgggcc tccactttct cattttgaaa atactgctct
     7561 tcctcctcat accactccct gattcgacca gattgagtga tttgcaaagg atttagtaaa
     7621 tcagacttct ccttaacctc agtcaacaag tcctcatcca gtcccaattc ctgagcagcc
     7681 tgaataaaat catgaaataa ctgccaaatc agagattggt cataggtatt gccaatcgaa
     7741 atcggcccat gttctggaga ataagacgga gaagacaccc aacgctgcgc ctgctgatcc
     7801 ttatgtaaaa aggcattcca aaaacgaacc gtttccctca acatgggata aattttctcc
     7861 ctgagatagt cttggtccct ataaaatgaa taggcttcat aaacggtttg catcatccac
     7921 gcattggcag ctggtgacca accccaatag taatcccaac caggtgccgt ccaaccaaag
     7981 ggagtcgctt gagtatgaac caaccaacca ttttcctcac ctttctgaga gacgattcct
     8041 gcatacttta cagccgctag acgaccatag acacgcaaat catctacata gttgatgacc
     8101 ggaaagaccg cctctaggag attggtaaca taggctggcc aataattcat ctgcagattg
     8161 acatttaagt gatagtccga attccaagga ggattgtcga ccgcattcca gactccctgt
     8221 aggttagctg gtagagcatc tgggcagtct ctggacgaac taatcaataa ataccgtcca
     8281 tactggaaga acagctcctc caaagcctgc ccttcttgtg gcttataatt ttttaacaaa
     8341 tcatctgtag tggatgcgtc aacatcagct tccaaatcca attgaacacg ctggaataag
     8401 gcttggtagt cctcgatatg ccttgatttc aattgggtat agcccttttc tttagctgtg
     8461 tccaccaagt ctatcacctg ttgctctaaa tctagtttct tgcgataatt gctagcagga
     8521 ttttgggcaa aatccgtctt agcggccaag aagagattgg cataactggc tcctgatatc
     8581 tgaaccctat ctgaccaaac tctaatatct ccatccgttt cccaagctag ataactagca
     8641 aaccgcagat cattatcctt aactcttccc ttcatcaaga tatgagaatc agtaatatcc
     8701 aacttacact ccttgtaatc agatttttcc tgctcatact tttcatcaga agccaaatca
     8761 caggtcaagg atagttctat agtaaaatct agagtttccg ccccttcctt agtaaaacgc
     8821 tgaaccaaga gatcatctgg aaaactcgca aaagcttcac gttcaaatcg cgttccctta
     8881 tagacataag aagtcgtcac aagtgcctta ctaatattca gctgtctctg atagtccgtc
     8941 acctgagaca aagtcgtacc ttgctggctg aactcaatgt gaatatcccc aaaagacaga
     9001 taggtcccat attgactcgt ttttggccca attaggtgct gctcagccag ttccttagcc
     9061 agattgtaat ctctcttctc caaagcctgc cgaatctcag ctaaaaaaac atactgatcc
     9121 tgaagatttc caccctgata atctgaacta tcaggaagtg gacctccaga ccagagactt
     9181 ttttcattaa attgaatccg ttcagcccct atacggccaa atacttttgc tcctaaagaa
     9241 ccattaccta tcggtaaagc ttcttcttcc caacccatgt aagtggttga agctggttgt
     9301 ttgtaggcca gtacataatc ttgtttttta ttccttatca tacttccata ctaacataaa
     9361 aagcctagaa atcaatccta ggcttacaat tttttatttt ccaaggtagt attcagaaac
     9421 aacgttcaat ttttcgtcga attcgaatac caatggtggg aagttaggga tttccacgtc
     9481 catgatctca tcatctgaca aacctttgat gtgttttaca agggcacgga ttgagttacc
     9541 gtgagctcct acgaatacgt ttttaccatc tttaagagct ggagcgattt tatcttccca
     9601 gaatggaaga gcacgttcca aagtcacttt caagttttca gcatctggga ttactgagtc
     9661 gtcaagtgaa gcataacgac ggtctgtgtg agctgagtgc tcatcatcac ggtccatatt
     9721 tggaggcaat acatcgtatg aacgacgcca gatgtgaact tgctcatcac caaattgttc
     9781 agcagcttca gctttgtttt taccagtcaa accaccgtag tgacgttcgt tcaagcgcca
     9841 tgatttttca actggaaccc ataattggtc agaagcttca agagccaagt tagttgtttt
     9901 gatagcacgt ttcaatactg aagtgtaagc ttggtcaaat tcgataccag cttctttgat
     9961 caatttacca gcgtcaatcg cttgttgtgt acctttttca gacaaatcaa catcagccca
    10021 accagtgaaa aggttagctt tgttccattc agactcaccg tggcgagcaa aaaccaattt
    10081 taccattaga tggattctcc tttaaatttt ccgaggtttc ccctcgttta tctattctat
    10141 tttacacaat ttttcacaaa aaagctagtc aaaaccaaaa aggaaaggac tgtttgacaa
    10201 tgtttggcaa tcacattgtt tttggttgtt tctattctat cttcattatt taaccttttt
    10261 ttctgcgcat cgaataattt ttgagttgac tcttttagtt tagtaaacga gtcattattt
    10321 tccatagcta tgcctttgaa accttcctca gctttagtaa aataatcatc aaaaatattt
    10381 ttataaagat ctatataatc tgcataagtg cgtattgatt caatcgcatc gtctgttaca
    10441 accggtgtat cgaaagtgat tgtttctttt gaactattgg atgttgctac tgtcttctca
    10501 tcattacttg ttgaagtatt ctttgaactt tatgttccac atgcaactag aagagaaaga
    10561 gataatagag ctactcctat accgataaac ttttttgttc ttttcatgct aaaatacctt
    10621 ttattcttct gatttgaatt tcttcaatgt tgaaaggaat agagatcctc cgataatagc
    10681 aaaaatcccc ccaacccatc ctaagaacgg aatagaatga gactaactcc accagaaaca
    10741 atcattagta cagacggagc tgcacctaca cgcttatctc ctttatagta aacaatagca
    10801 atgataccaa gaacaagatt tgcaatcttc aaggcattca agagtaaggc tacacctgaa
    10861 aaagcccctg cagtagctcc tccattaaga gttgtagcag ctgtgtttac cgctattccc
    10921 aacaagacaa aaggaccaat aagaagtaaa attcctccca caagaccgac gataccacta
    10981 attaaagcaa gtctttttaa ttttataata aaa
//
LOCUS       DBERDS010000055        10867 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.055, whole genome shotgun sequence.
ACCESSION   DBERDS010000055 DBERDS010000000
VERSION     DBERDS010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.055"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            118..897
                     /locus_tag="ACL73E_001762"
     CDS             118..897
                     /locus_tag="ACL73E_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801691.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYTF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            899..1081
                     /locus_tag="ACL73E_001763"
                     /pseudo
     CDS             899..1081
                     /locus_tag="ACL73E_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1543..1776
                     /locus_tag="ACL73E_001764"
     CDS             1543..1776
                     /locus_tag="ACL73E_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGS0801692.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPIMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            1776..3110
                     /locus_tag="ACL73E_001765"
     CDS             1776..3110
                     /locus_tag="ACL73E_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGS0801693.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQERFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIADESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            3120..3374
                     /locus_tag="ACL73E_001766"
     CDS             3120..3374
                     /locus_tag="ACL73E_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGS0801694.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            3470..3865
                     /locus_tag="ACL73E_001767"
     CDS             3470..3865
                     /locus_tag="ACL73E_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGS0801695.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            4391..4726
                     /locus_tag="ACL73E_001768"
     CDS             4391..4726
                     /locus_tag="ACL73E_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801696.1"
                     /translation="MSHQEKLERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDG
                     ICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIK
                     KARKKDGKN"
     gene            4713..5273
                     /locus_tag="ACL73E_001769"
     CDS             4713..5273
                     /locus_tag="ACL73E_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGS0801697.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            5273..5851
                     /locus_tag="ACL73E_001770"
     CDS             5273..5851
                     /locus_tag="ACL73E_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGS0801698.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            5844..8495
                     /locus_tag="ACL73E_001771"
     CDS             5844..8495
                     /locus_tag="ACL73E_001771"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGS0801699.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            8565..9320
                     /locus_tag="ACL73E_001772"
     CDS             8565..9320
                     /locus_tag="ACL73E_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGS0801700.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            9599..10402
                     /locus_tag="ACL73E_001773"
     CDS             9599..10402
                     /locus_tag="ACL73E_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGS0801701.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQARGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADMVKKIQHFISGIWQIHPFREGNARTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(10518..>10867)
                     /locus_tag="ACL73E_001774"
     CDS             complement(10518..>10867)
                     /locus_tag="ACL73E_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGS0801702.1"
                     /translation="QTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASM
                     SRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLK
                     GLSPVQYRTKSFG"
BASE COUNT         3262 a         2033 c         2416 g         3156 t
ORIGIN      
        1 tttcatttca ctataaaaaa ggggttctgt attttttaat gttatctaat tagaaaatgc
       61 tttttttgta ggaaatataa tatgataagg tgcaaaaaag aaataaggag tttgtatatg
      121 gctgaacaag acttagctat gcaagtattg caacaagtgg tgaaactacc tgttgttaag
      181 gttgatcgtt cgaaattttt agtggataag ttttccaaag aattgggtcc acaggacatt
      241 cctaccttat tggaacaagg tccaacgtct ctcttatctc aagaaatctt agatcgagtg
      301 gctaatgcct gtattaggga taatgtttta ttagcgagtg ggacttctgt tttggcagga
      361 ttacctggag ggcttgctat ggcaattacc attccagctg atgtggctca attttatact
      421 ttctctctaa aattggctca agaattaggt tatatttatg gttatgagga tctttgggct
      481 tcacgcgagg agttgagtga agatgctcaa aataccctct tgctttatct aggcgtcatg
      541 ttgggggtga atggaaccgc tgctttgcta cgtgctggtg gtataacaat tgccaaacag
      601 gtaatgaaaa cagtgcctaa taaagcttta acaaagacgc tttggtaccc tattttgaaa
      661 aaagtcttaa aaatatttgg tgtgaatctt accaagggag ggctggccaa aggaataggg
      721 aaatttattc ctatcttggg tggtatcatt tcaggtggtt taacctttgc aactatgaaa
      781 ccgatgggtg aaagcttgca gaaagaattg tccaagctag ttaactatag tgaagttcaa
      841 tatcaagaag atgttgaaac aatccgaaaa gaggctgaaa tcatcgaagg agagtaatat
      901 gggactcata aaaactctag ctaaaattta tggtaattac tttttgaccg tgtaaggtgt
      961 aaaagtaatg aaaacgataa agaaagatga taatgccgtt gtcggtctgg ggaaactttt
     1021 tattgccgac aagttaatgg atacggctcg gtggctcatt aagccagagg ataaaaaatg
     1081 aaatttttct ggggacttct tgccattatt tttatcaaac cgattattgg gattgtgaaa
     1141 ttcttttgga tgatcatctc ttttgcagtc caattgctgt tttacaagat agtgtttaag
     1201 atattggatt ggctctttaa acttatctag atggtaatcc aagtcgcaga gaactagcag
     1261 gaactccact gctagttttt tattctcttt ccatatggta taatataagc agtaaaatca
     1321 ttttatactc ttcgaaaatc tcttcaaacc acgtcagctt caccttgctg tatatatgtt
     1381 actgacttcg tcagttctat ccacaacctc aaaacggtgt tttgagctga cttcgtcagt
     1441 tctatctaca acctcaaagc actgttttga gcaacctgcg gctagcttcc tagtttgctc
     1501 tttgattttc attgagtatt agaacataca atggaggtcg tcatggacaa tatcatcgat
     1561 gtgtcaattc ctgttgcaga agtggtggac aagcatccag aagtcttgga aattctagtg
     1621 gagttgggtt ttaaacccct tgccaatccc ataatgcgca atacagttgg tcgtaaagta
     1681 tcacttaaac agggttctaa gctagcagga actcctatgg acaagattgt acgcacactg
     1741 gaagcgaatg gctacgaagt gattggatta gactaatgac agatgaacgg attcatatcc
     1801 tacgggatat tttgttagaa ttgcacaatg gcgcctctcc tgagtcggtt caagagcgct
     1861 ttgatgcgac ctttacgggc gtgtcagcca tcgagatttc ccttatggag cacgagctga
     1921 tgaactcgga ttcgggcgtc acttttgaag atgttatgga actctgtgat gtccatgcca
     1981 atctttttaa aaatgctatc aaaggtgtcg aagttttaga taccgaacac cctgggcacc
     2041 cagttcgtgt ctttaaggaa gaaaatttgg ccctccgtgc agctttgatt cgcattcgta
     2101 gattgttaga tacctatgag tctatggaag acgaggaaat gcttgcggag atgcgcaagg
     2161 gcttggtgcg tcagatggga cttgtggggc aatttgacat ccattaccaa cgtaaggaag
     2221 aactcttctt tcctatcatg gagcgctatg gacacgattc acctcccaaa gttatgtggg
     2281 gagtggatga tcagattagg gaactctttc aaacagctct aacgacagcc aagtcactac
     2341 cagaagtgtc aattagcagt gtaaaggaag cttttgaagc ttttgcgaca gagtttgaaa
     2401 gtatgatttt caaggaagag tccatcctcc tcatgattct ccttgagtct tttactcagg
     2461 atgactggct tcagattgcg gatgagagcg atgcctatgg ctatgccatc atccgtccgt
     2521 cagagaaatg ggtgccagaa cgacagagct ttattgagga aaagattgca gaggagcctg
     2581 tacagctaga tacggcagaa ggtcaagttc aacaagtcat agatacgcca gaaggccatt
     2641 ttaccattac ctttacccct aaggaaaagg aagctgtgct ggaccgccat agtcaacagg
     2701 cttttggtaa tggctatctt tcagtcgagc aggccaatct catcctcaat catctcccta
     2761 tggagattac ctttgtcaat aaagaagata ttttccagta ttacaatgac aatacgccag
     2821 ctgatgagat gattttcaaa cggacgccgt cccaagtcgg gcgcaatgtc gaactctgtc
     2881 atccgcctaa gtatttggac aaggtcaaaa ctatcatgaa ggggcttcgt gaggggacca
     2941 aggacaagta tgaaatgtgg ttcaagtctg agtcgcgagg taagtttgtc cacatcacct
     3001 atgctgcagt acacgatgaa gacggagaat tccaaggagt gttggagtat gttcaggata
     3061 tccagcccta ccgtgagatt gatacggact attttcgtgg attagaataa ggagaaaaaa
     3121 tgagttacga acaagaattt atgaaggaat ttgaagcttg ggtcaatacc caaatcatga
     3181 ttaacgacat ggcgcacaag gaaagtcaaa aagtttacga agaagaccag gacgagcgtg
     3241 ccaaagatgc catgattcgc tacgagagtc gcttggatgc ttatcagttc ttgcttggta
     3301 agtttgaaaa cttcaaagca ggcaagggat tccatgattt gccagaaggc ttgtttggtg
     3361 agcgaaatta ttaaacgaga aagattcttg atttttcact aaaatcttga tagaatgttt
     3421 atgttaaatc cttgtcagag cagggatttt ttattgaaag gattttatca tgtcaaagaa
     3481 actcaatcgt aaaaaacaat tacgaaatgg cctccgtcgc gcaggtgcct tttcaagtac
     3541 tgtgactaag gttgtagatg agacaaaaaa agtcgtgaag cgtgcagaac agtcagcaag
     3601 cgcagctggt aaggctgttt ctaaaaaagt tgaacaagca gtagaagcta ccaaagagca
     3661 agctcaaaaa gtagctaatt ctgtagaaga ttttgcagca aacttgggtg gacttccact
     3721 tgatcgtgcc aaaactttct atgatgaagg aatcaagtct gcttcagatt tcaaaaactg
     3781 gactgaaaaa gaactccttg ccttgaaagg aatcggccca gctaccatca agaaattgaa
     3841 agaaaatggc atcaagttca agtaattttt cttgagcctt gcatttccga gaaaaacttg
     3901 ctacaataga gccattagag gtgttttgaa tcccacattt tacagaaagt ggcggcgctg
     3961 agaagtccac aaatgtgtca aaactggttg ctaatgactg aaaaaatgaa atatttctgt
     4021 ctttttattt taaagactaa agatgcgggc ttggcccgaa attgggtggt accgcggata
     4081 aacacattcg tccctgtcat gtagatggca gggcttttct tttgtgtctt agtcaaagga
     4141 ggttgttata aaacaatcat ttaaaactaa taaactatat tatggttttc ctgtttttat
     4201 tttaggatat caagattaga attttggcta taacatcacg acctgtagtt cctcttatag
     4261 tctaggagat tgggttgtga ttggagtcgt tgcgagagag aatgccgcag agcagatcaa
     4321 acagtatcaa aaatttactg tgaatatttc tgatgaaact tctatgcttg cgatggagta
     4381 ggctggtttt atcagtcatc aggagaaatt ggaacgtttg ggagtgcatt atgaaatttc
     4441 tgaacgaact cagattccta ttttagacgc ctgtccactt gttttagatt gtcgggtaga
     4501 taggattgtt gaggaagacg gtatttgcca catctttgcc aagattcttg agcgacttgt
     4561 tgccccagaa ctcctggatg aaaagggaca ttttaaaaat caactgtttg ccccaaccta
     4621 tttcatggga gatggatatc agcgcgttta tcgctatctg gacaagcgtg tagatatgaa
     4681 gggcagtttc atcaaaaaag cgaggaagaa ggatggcaag aactgagctg ccagataaaa
     4741 tcgaaacaga acgtctcgtt ttacgagtcc gtactgtggc ggatgctgag gatatctttg
     4801 actatgctag tttgccagag gtcgcctatc cagcaggttt tcctccagtc aagaccttgg
     4861 aagatgagat ttattatctg gagcacattc ttccggagcg taatcaaaag gaaaatctcc
     4921 cagcaggcta cgggattgtc gtcaaaggaa cggataagat cgttggctct atctatttca
     4981 accatcgcca tgaagatgat gtgatggaaa tcggctatac cttacactca gactattggg
     5041 ggcgaggtta tgtgccagaa gctgcgcgtg ccttgattga cttagccttt aaagatttgg
     5101 gtcttcacaa gattgaacta acttgctttg gatataacct tcaaagtcaa cgagtcgcgg
     5161 aaaagcttgg ctttaccctc gaagctcgca taagagaccg taaagatgct caaggcaact
     5221 gctgtgatga tttgagatat gccttgctga agagtgagtg ggaggtgatt tgatgcatct
     5281 tttcatcatt ggtgctccag catcaggaaa aatgaccatt ggtcaagaat tatctcgact
     5341 gacggatgct accctatttt ataaccatca agccattgat tttgcactag aaatctatca
     5401 ggactataca gaggaaatgt gggaatttgt tcgtggaatc actttttcat tccttggagc
     5461 aagtgcaaga aatcagcgat cagtaatttt aacagatgta attgattttt caaatcagta
     5521 tcagctgatg tatttaaagc aaattcagaa tttgttggat gattatcatc aagagattct
     5581 ttttgttgag ttggaaacaa gtcttgaaga gtgcatacgt cgaaatcgaa cggagaatcg
     5641 attaaagcac aaacccttaa aacgacatat tgaggtatct gaaagagaaa ttttagagac
     5701 cgctgaaaca cttcaattaa attcccaata tcaaccgaat gagttgcacc actactttaa
     5761 aataaataat acgaatttgt ctgcagaaga agctgctaag caaattcaaa ataaaataaa
     5821 caaaatagag aaaggacaca cacatgtcta aagaactttc atctaaatac aatccagccg
     5881 aggttgaggc tggtcgttac caaaaatggc ttgatgcgga tgttttcaag ccttcaggcg
     5941 atcaaaaggc taagccttat tcaatcgtga ttccaccacc aaacgtaact gggaaacttc
     6001 accttggtca cgcttgggat acgactttgc aggatatcat catccgtcaa aaacgcatgc
     6061 agggctttga taccctttgg cttccaggta tggaccacgc tggtattgcg actcaggcta
     6121 aggttgagga gcgcttacgt ggtgagggta ttacgcgtta tgacctaggt cgtgagtctt
     6181 tcttgacgaa ggtctgggaa tggaaagacg aatatgccac taccatcaag gaacaatggg
     6241 gcaagatggg gctttctgta gactattctc gtgagcgttt cactcttgac gaaggtttgt
     6301 caaaagctgt tcgtaaggtc tttgtggacc tttacaagaa aggctggatc tatcgtggtg
     6361 agtttatcat caactgggac ccagcagctc gcacagccct ttctgatatt gaggtgattc
     6421 acaaggatgt agaaggtgcc ttctaccaca tgaattacat gctggaagat ggttcacgcg
     6481 cccttgaagt tgctacaact cgtcctgaga ctatgtttgg ggacgttgcg gttgcgatta
     6541 atccagaaga cccgcgctac aaggacttga ttggtaaaaa cgtcatcctt ccaatcgcta
     6601 ataaactcat cccaatcgtt ggagatgagc acgcagatcc tgagtttggt actggtgtcg
     6661 tgaaaatcac acctgcccac gatccaaatg acttcttggt tggccaacgt cataacttgc
     6721 cacaagtcaa cgtcatgaac gacgacggaa ctatgaatga gcttgccttt gaattttcag
     6781 gcatggatcg ttttgaagct cgtaaggcag tcgttgctaa gttggaagaa atcggtgccc
     6841 ttgtcaaaat cgaaaaacgt gtccattcag tcggtcactc agaacggaca ggtgtcgtag
     6901 ttgagccacg cttgtctact caatggttcg tcaagatgga ccaattggct aagaacgcca
     6961 ttgccaacca agacacagag gacaaggtcg aattctaccc acctcgtttc aacgatacct
     7021 tccttcaatg gatggaaaat gtccacgact gggttatctc tcgtcagctt tggtggggtc
     7081 accaaatccc tgcctggtac aatgctgatg gtgaaatgta tgtcggcgaa gaagctccag
     7141 aaggtgacgg atggactcag gacgaagacg tcttggatac ttggttcagt tctgccctct
     7201 ggccattttc aaccatgggc tggcctgaag tcgactcaga agactttaaa cgttatttcc
     7261 caacttcaac cttggtaaca ggttacgaca tcatcttctt ctgggtgtct cgtatgatct
     7321 tccagtcatt ggaattcaca ggccgtcaac cattccaaaa cgtccttatc cacggtctca
     7381 ttcgtgacga gcaaggacgc aagatgtcta agtctctcgg taacgggatt gacccaatgg
     7441 atgttatcga gaaatacggt gccgatgccc ttcgatggtt cctttcaaac ggttctgcgc
     7501 caggacaaga cgtgcgtttc tcttatgaga aaatggatgc ttcatggaac tttattaaca
     7561 agatttggaa catttctcgc tatatcctca tgaacaatgg aggtttgacg ctggatgtgg
     7621 cgcatgacaa tgtcacaaaa gttgcaacag gtgaggctgg taatgtgacg gaccgctgga
     7681 ttctccacaa tctcaacgaa accattgcaa aagttactga aaactttgat aagttcgagt
     7741 ttggtgtggc tggtcatatc ctttacaact tcatttggga agaatttgcc aactggtatg
     7801 ttgagttgac caaggaagtc ctttatagcg ataacgaaga agagaaagtc atcacacgtt
     7861 ctgttctact atacactttg gacaagatcc ttcgtctcct tcacccaatc atgccattcg
     7921 tgacagagga aatctttgga caaatctcag aaggttctat cgtgacagct gcatacccaa
     7981 ctgttaatct agcctttgaa gaccttgcgg ctcacactgg tgtggaaagt ctcaaagact
     8041 tgattcgtgc tgttcggaat gcgcgtgcgg aagtaaatgt agcaccaagc aagcctatca
     8101 ccatccttgt taagacaagc gatagcgact tggaagcctt ctttaacagc aatgtcaact
     8161 atatcaaacg ctttacaaat ccagaacact tggaaatcgc atcaaccatc cctgcacctg
     8221 aactggctat gtcaagcgtt attacaggag ccgaaatctt cttgccactg gccgatctcc
     8281 tcaatgttga agaagaacta gctcgtctcg acaaagaact cgctaaatgg caaaaagaac
     8341 tggacatggt tggtaagaaa ctctctaacg aacgcttcgt cgccaacgct aaaccagaag
     8401 ttgtccaaaa agaaaaagac aaacaagccg actaccaagc caagtatgat gtgaccgtag
     8461 cacgtattga tgagatgaag aagttggtga aataaacaca gaaacacggt gatgagccgt
     8521 gttttttggt ataatgaaat caatatctat tgatggagaa agtgatgtcc aaacaccctc
     8581 attatgaatt gttaaattta attggctacg gtcttgccaa gtttgacaag ctttttataa
     8641 aagaatttca atgctctagc aagtcggagt tttatcgcta tgtggtttct ctgggaattg
     8701 ctgaaacaac tggagttgta aaaaatagaa tggatttatt tgatccttat tttgacaata
     8761 atcgaaaagg ttggtggcag aaagctgaag tttatcgttt tcgtaaagat ttaattgata
     8821 tgatgtttgg aaatgaagat gttcatagtt atgctgaaat agttaaaatg ttacttgcca
     8881 gtgaagggaa gaaaacaggc ataaccatcg ttgaaaaacc aatagttcga actaaattca
     8941 aacgtctaca ggaaacggga atggaggctg agaattattt tatccttcat tttgataaag
     9001 aagaaaaatt ccaaggtgga cagttaaccg atgcccgtct ttatggtgat ggatatgact
     9061 ttcaggtaga tgtccaagag tattcttacc ttgccgaagt aaaaggtatc cgaaaatcta
     9121 aggggcgtgt gcgtttaact gcaaaagaat ttgaaaaagt caaggagttt caatcggatt
     9181 ttattttatc cttggtcaca aatctagatg atattccaaa gttagtgtta atcgataatc
     9241 ctttaaaaca ttttgagttt aaaaagaata ttatcaaaaa tgaaatcatt gaatatagaa
     9301 gcgtagagga tttgtattag ttccccctta acttttccag ttgaaggaac gagaagtctt
     9361 gataggtcaa cgacttaatg aactggaaat caacggtatt cgtttgacta agttttaaga
     9421 tggcgaaatc ggtattgaat ttatcagtag tgctgattat aactctttta ttatttacat
     9481 gaagtatata tatatatatc atagaaccta ttgtgaggac tttttatagt ttaagccagt
     9541 ttccaaccaa tttcgtgatt tactggtaat gaagaaaaac aattgaaagg atatttctat
     9601 gcaaccaact tacaacattg acaatccaaa cttgtcttat gaagctaagc gtgatttatg
     9661 gcggataggt tttggtctgc agaaagttga caatctagtg ccatcagctt atatggaatc
     9721 tttggctgag aaacaggctc ggggtgaact gacttatgag caggtttatg aggatgcaac
     9781 ggcttatcac catactattg atgcaagtac ggaggaggca gacttggttt ctctacgcat
     9841 tgtagaacta ttgtctcgaa gaggctttag cttcagtcct gcgaccttac ttgctattca
     9901 taaggagttg tttcaagata tatttgaacc ctcgattccg gtaggtcaat ttcgtcagac
     9961 taatatcaca aagaatgaac ctgttttgaa tggtgaaagt gttgtgtact ctgattactc
    10021 catgattcaa atgacattgg attatgattt taatcaggaa aaacaagttg catatgcgac
    10081 actaacccag gcggatatgg ttaaaaaaat ccagcatttt atttcaggaa tctggcagat
    10141 tcatccattt cgcgaaggaa acgctcggac agtaacggtc tttttgattc agtatcttcg
    10201 tgagtttggt tttgatattg ataatatacc atttcagcaa cattccaagt attttcgtga
    10261 tgccttggta ttagataatg caaagatttt acagcgacgt cctgagtttt taacagcttt
    10321 ttttgaaaat ctcttgctcg gtggtcaaaa tgatttgtct tcagaaaaaa tgtatctaga
    10381 tttagacctc gatttttcat aatccaaata ctgagtaaac attgaatttt aggaaaaaat
    10441 gaagtaaaca ttcccacaat aaaacgcata gtatcaagtg ttaaaatgta ctgcccccca
    10501 aaagttagac aattaattta tccgaaggat ttagttctgt attgcacagg gctaagtcct
    10561 tttagtttta ccttaattct cttattgttg taataatcaa tatagtctac aatggcttgt
    10621 tccaattgct taagcgactg aaacgacttc tcataaccgt aaaacatttc cgatttcaga
    10681 atcccaaaga aggactccat cataccattg tctgggctgt tacccttacg tgacatggat
    10741 gcttgaattc ccttaccctc aagaaactga tgataagaat cgtgttgata ttgccagcct
    10801 tggtcactat ggagaatcgt attctcgtag tgcttctctg tgaatgcctg ttccaacatt
    10861 gtttgta
//
LOCUS       DBERDS010000056        10757 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.056, whole genome shotgun sequence.
ACCESSION   DBERDS010000056 DBERDS010000000
VERSION     DBERDS010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.056"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            125..289
                     /locus_tag="ACL73E_001775"
     CDS             125..289
                     /locus_tag="ACL73E_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGS0801703.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            373..939
                     /gene="amaP"
                     /locus_tag="ACL73E_001776"
     CDS             373..939
                     /gene="amaP"
                     /locus_tag="ACL73E_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGS0801704.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            951..1121
                     /locus_tag="ACL73E_001777"
     CDS             951..1121
                     /locus_tag="ACL73E_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGS0801705.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1160..1768
                     /locus_tag="ACL73E_001778"
     CDS             1160..1768
                     /locus_tag="ACL73E_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGS0801706.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1799..2002
                     /locus_tag="ACL73E_001779"
     CDS             1799..2002
                     /locus_tag="ACL73E_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGS0801707.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2095..2334)
                     /locus_tag="ACL73E_001780"
     CDS             complement(2095..2334)
                     /locus_tag="ACL73E_001780"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0801708.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            2613..2858
                     /locus_tag="ACL73E_001781"
     CDS             2613..2858
                     /locus_tag="ACL73E_001781"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGS0801709.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3136..3906)
                     /locus_tag="ACL73E_001782"
     CDS             complement(3136..3906)
                     /locus_tag="ACL73E_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGS0801710.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLYQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3921..4769)
                     /locus_tag="ACL73E_001783"
     CDS             complement(3921..4769)
                     /locus_tag="ACL73E_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGS0801711.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4766..6241)
                     /locus_tag="ACL73E_001784"
     CDS             complement(4766..6241)
                     /locus_tag="ACL73E_001784"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGS0801712.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHTLGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6565..7921)
                     /locus_tag="ACL73E_001785"
                     /pseudo
     CDS             complement(6565..7921)
                     /locus_tag="ACL73E_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(7931..8248)
                     /locus_tag="ACL73E_001786"
     CDS             complement(7931..8248)
                     /locus_tag="ACL73E_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0801713.1"
                     /translation="MNESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8265..8582)
                     /locus_tag="ACL73E_001787"
     CDS             complement(8265..8582)
                     /locus_tag="ACL73E_001787"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0801714.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8597..9493)
                     /locus_tag="ACL73E_001788"
     CDS             complement(8597..9493)
                     /locus_tag="ACL73E_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGS0801715.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKTVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9496..>10757)
                     /locus_tag="ACL73E_001789"
     CDS             complement(9496..>10757)
                     /locus_tag="ACL73E_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGS0801716.1"
                     /translation="EKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMVI
                     ASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGIV
                     SLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMPD
                     GVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNVI
                     GLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFMD
                     NFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIVL
                     NILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLLQ
                     IVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3711 a         2173 c         1666 g         3207 t
ORIGIN      
        1 aataatcaaa gaaattgatt ttttgatatt aaaataaaaa aggagggtag gcagtgttgt
       61 gatcaattat tgctggaggt cttattggtc tcttggcagg taaaatcact aaaaaagtag
      121 ttctatggga atcatcgcaa atgtattcgc tggtttagtc ggggcatatg caggacaatc
      181 tcttttaggt agttggggtc catcaatcgc tggaatggct ttgctcccat ctattgtagg
      241 tgcagcgatt gtgattactg tagtgtcatt ctttacaggt agaaagtaaa cttttcgcca
      301 gtaaagttag caaactattt ttaaatcaat gacgggaaaa atagtttaaa tgttaaatcg
      361 aaaggattgt atatgtcaaa agcaaagaaa atatgtttca ttattttctg tattttaatc
      421 ttgacaattt tccttcctgt tttgatagat tatcatcaag ttagtgatct aggtattcat
      481 ctactgagct ggagacagaa ctccgtagtt gaattctatc ttgctagata tgtcttttgg
      541 gggacagtgg ttctatcaac tttagtttta ttatccattt tagttgtgat gttttatcct
      601 aaacgttact tggaaatcca acttgaaact aaaaacgata cattaaaatt aaagaattcg
      661 gcaatcgaag gttttgttag aagtttggtg agtgatcata gattgatcaa gaacccaact
      721 gttcatgtaa atttacgaaa aaataaatgt ttcgttcatg tagaaggtaa aattcttcct
      781 tcagacaaca tcgctgacag atgccaaata attcaaaatg aaataactaa tggattgaag
      841 cagttttttg gtattgagcg tcaagtaaaa cttgaagttg cagtaaaaaa ttaccaacca
      901 aaacctcaaa acaaaaagac tgttagtcgt gtgaagtaag gaagtaaaaa atggaatggc
      961 ttaaacaata tcgatatcca attatcgctg gtctcatagg cgtatttctg gcttgtttga
     1021 ttgtctcctt tggcttcttc aaaacaatat ttgtattgat tttaggagca ctgggagttg
     1081 cagctggatt atatatcgaa aaaaactata tagataaata aaaaaataaa aattactaat
     1141 ttaattaaag gagtttcata tgtcaaacga aaaaaacaca aacactaacg tagaaaagaa
     1201 agatgctact gttgtagctc acgaaatcaa aggggaactt acttacgaag ataaagttat
     1261 ccaaaaaatc attggtcttt cactagaaaa cgtttcaggt cttttgggaa tcgatggtgg
     1321 tttcttctca aatcttaaag aaaaaatcgt taacagcgat gacgtaacaa gtggtgttaa
     1381 cgtagaagtt ggtaaaacac aagttgcagt tgacttaaac gttattgttg agtaccaaaa
     1441 aaatgttcca gctttatatt cagaaatcag agaaatcgta tcttcagaag ttgctaaaat
     1501 gactgacttg gaaattgttg aaatcaacgt aaacgttgtc gacatcaaaa ctaaagaaca
     1561 gcatgaagca gactcagtaa gccttcaaga tcgcgtatct gacgttgctg aatcaacagg
     1621 agaattcact tcagaacaat tcgaaaaagc taaatctggt cttggatctg gtttctcaac
     1681 tgttcaagaa aaagttagcg aaggtgtaga agctgttaaa ggtgcagcaa atggtgtagt
     1741 atctcacgaa aacactcgtg taaactaaga taaaataaat ataacaggag aaattatcat
     1801 gtcagtagaa gaaaaattaa atcaagctaa aggttctatt aaagaaggtg ttgggaaagc
     1861 catcggtgat gaaaaaatgg aaaaagaagg agcagctgaa aaagttgttt ctaaagtaaa
     1921 agaagttgcc gaagacgcta aagacgctgt agaaggtgct gtagaaggtg ttaaaaacat
     1981 gttgagtggc gacgataaat aaggttattg gtaacattag tcaaaagagt ctgagtcaag
     2041 atgattctca gaaaacaaaa agctagagat tcccaattgc ggaactctag ctttttaatt
     2101 ttgcctcttt ctcttattat atttcagcag gttgttggcc atgagtatga atcccatgtc
     2161 aattctcact tgacgcttac ctctcagatg acatctctta taacccaaac aaacctttat
     2221 ctgcccaaag acagatttca tatcaatctt acgtttagcg aaaatttgtc tacccttgga
     2281 agataaaagt gcctgatatt ctttagtttt taaacactgg taacgttcat tcatatacag
     2341 tcccttttga ggggctgatt caggttcata atcgcagtca acattgattt caaggctgtt
     2401 tgctttctat ctcccctttt tcatgatata ttttcgtaca ggttcttcaa tagtttctat
     2461 agtaaaatga accaaaaata gtacacgttg cggtataatg ttcttgtggc atattcatta
     2521 gattttcgta aacagttctc tcctatttgt gagcgaacaa gtatagtcaa ttgattgtca
     2581 gtttgaagac caagagtcgt aaggcaaagg atatggcaga atccatccaa gggtggctgg
     2641 cacaatttct agtgaacctc tttaaatcta ttacgtttga ctgtggaaaa gagttttcaa
     2701 aatggaaaga tatttccaat catcacgata gtgagagctt ttttgcgaat ctaggatgtt
     2761 caagacagcg gcgtctcaac gaacattcaa atagactttt aaggtgtcat gacttgccaa
     2821 agcagacaga tttcaacgaa gtcagtcaag aattttaggc tggacaaaaa ctcaatttca
     2881 ggagaaaatg aaataaatat tcccacaata aaacgcatag tatcaaagtt tttccaacac
     2941 ctgatattat gcatttttta attttaaaga ctttttccca gcctcaagaa atcacatccc
     3001 acctaaatcc tttggatacc aaatacctca tcaggtattt tctgagttgg taagactgtc
     3061 tagcttaatt tgacaaatgg agggcgttaa atccagtttt tacaggaagt ctatttaaat
     3121 attttcacac tgaccttaca aaatatgaaa taaattatat aaagtcattc ccatgacaaa
     3181 gaataacatc cctttaaaac agtatcttac ccaattttca ggtaagactt ttgatacaac
     3241 cgtccccaat acccctccgc atatagaagc aagaaaaata actggaacag gtgctaaatg
     3301 atactgattt aaacctgtaa ccacaacaat tgtagccaaa tgagacagct gggaaaagaa
     3361 aataattgca agagaataca tcgttgcttc ttttatcgaa atagaaaaaa acaccatcaa
     3421 taaagataca ttgagcggac caccaccaat ccctaaaaaa ctagaaatta agcccaatag
     3481 aagaccacaa atcatataga atcctatctt atcaaattga taagtttttt taaaatctgt
     3541 taaaacaaat gatacaagta acatcacaaa tagtaaaatc atttgaacaa tagatactag
     3601 ccgtactgat aattgatata acaaaacttg aaaaataaga tgacctagaa atcctcctaa
     3661 aacagaagaa aaggataccg taaaaatcaa tctccatttt atctctttac tttgtgaaaa
     3721 tcttttgatt gttgaaataa tcgccattat aaaaacagag aaactagaat aaaaagcaat
     3781 atcactgacc gaatggtatc caaaactatc cataagtggc ttaattataa ttccaccacc
     3841 catgcctgat atagaaccca atccactagc tattataatg attagaaaat aaataatctc
     3901 aaccactttt taagtccatc ctattctttc aaacatctaa aacctagatg gctactagtg
     3961 gaagtagaaa tacatccatt tctagcagct actcggtatc gattacaata agaacaatga
     4021 cataaaaagg aacctcctct gatagcatac tcctcatctt gtatcccata ttttggtaac
     4081 tcatagtcat cttcattaaa actagctaat aaggtatatc tcggattgcg acaccattcc
     4141 caaacattcc caatcatttg atatagacca aaatcattag gtaaaaattc atagacagga
     4201 gccgttccta taaatccatc taaggcagta ttttcataag gaaatcttcc ttgccaagta
     4261 ttggcatgat aatatccacc ttctaaaaga gtatctcccc aaggatattc agattgtctt
     4321 cctcctctag cagcatattc ccactgtgct tcagtcggta aagacattcc gctccaatta
     4381 cagaaagcca atgcatcttc taaagcaaca tgaactactg gatggtcttc taaacccact
     4441 agattactgt tctcaccgta gggatgtttc cagcaagcgt tcgaaacttg taaccaccac
     4501 ggagccccag caggatgagg atatccctcc ctttctgcct ccggaacgaa caatataaaa
     4561 acaaaagacc actcttgtcg ctcagctagt gttttatagc ctgtttcttt cacaaattga
     4621 gcaaattctt gattcgtaac tggagtatcc gcaatggaaa aatcctttac actaacagcg
     4681 acttgaggac cttcaaaatc atctaaaaag ccctcttcag aatttgttcc catcataaat
     4741 gtcccaccct tgattttttt cattttcatg attgactatc ccccgttttc gttagagttg
     4801 gcgttatttt agaaagttca acaggaacta actcttcatc cacaacaaaa ccttcttctc
     4861 tatatctaag aaagtctact aattttttct tcatctgacg aacaataggt tgatattttt
     4921 cacttggata caaatcattc atttcatgcg gatctttttt catatcaaat aactgataat
     4981 gatttaaaac aggaaaccag ataaatttcc actggtctgt caaaatatat tgactagaat
     5041 cttttcctaa agtatgttca ccatgaaatt ctgttcgcca cccctcgtac tgtccaaata
     5101 ataaattctt aacactccgt ccatctagtt catctgtagt agttcctcct gccaaatcca
     5161 cgagtgaagg aaaaatatct tgaattttca ctaattgctt gattgttccc ctattaccag
     5221 ctatcaatcc agccggatcg taaataaacg aaggaatgtg gatacttccc tgataaggat
     5281 atccctttct aaacagataa tgttcaccaa gctgatctcc atgatccgaa acaaaccaga
     5341 taatcgtatc tttatcatga cgaaattctt ttagggcagt caaaaagcga ctaatttgat
     5401 ggtctatatg agtaatcaat ccaaaataag cagcaaccat tcttctttga tcatcttcct
     5461 ttaatttccc tcttaaagca taaatagacg gaatttgctt ttctaatact tcccaattcc
     5521 cgatatgcaa atcgagaaat tgaggcaagc gttccatata catatcaaaa tagtattttg
     5581 ggggatttaa tggagcatgt ggtttttcaa aagacatttt gagaaaaaaa ggaaccgttg
     5641 gatctcttct ttgtaaaaat gaaatggact cactcacaac ccagtttgtt ggatgtaact
     5701 tctcatcttt atcccaaggt ctagcttccc aagaattaca atccattccg tcatcaatca
     5761 aatcaacatc ataaccaact ttacccttta aaaaggctag atagtcacta gcataatcaa
     5821 attgacttcc ataagcctta tcatactttc tatcaacatg tagataccca tcgtgaagta
     5881 agacatgatc aaacccaagt ctctgtctgg aaggaaaaac atgcatctta ccaatacact
     5941 ctgtttgata acccatatct ttaaagactt ttggaagagt attagtaaaa ttccaaggca
     6001 cctcatcttg ataaccaact cgtccacttt tatcttggtc taagccagtc aataaagctg
     6061 ccctagcagg aacgcaagaa ggaactggag aataggcatt ttcaaaatta taacctacac
     6121 tagccatcat atctaatgtt ggagtgctaa ctagcttatc cttactattc aaggataagg
     6181 cgtctgctct catttgatct acaacaatca aaataatatt tggctgtttt gtctgaacca
     6241 taaaatctcc tttctaatat ggcaaaagag gcacaagaag atatctacct ttactgcacc
     6301 cctttctata tcaatctctc tatataaaac aataacattc ttgttatgtt ttatagaaaa
     6361 atgaactaaa atatgactaa atcgattagg aaattcaaat cattttctag tactatttta
     6421 gaagttacag tgtactattc caacttcaat aaactataaa cctttgtcta ataacaattt
     6481 tagtggagat aagaaatcct acacctaact caatcttaca cgtaatctat ttctatttta
     6541 tcacaaaaaa cgcaagtaag accattaact caattcagtt ttatctgcca ttttcacaaa
     6601 tgggaaataa gtcaagacac taataatcaa acaaacaact gataagatga tggcacgcca
     6661 atcaaatgct gtagagaaga aaccatataa aattggaggc attacccaag taacattttg
     6721 tgtaacaggt gaaacaagac cccagcttgt tgcccagtaa gctaccgttg ccatgaaaac
     6781 cgggctaagt acaaatggta taaatagcaa aggattcaag acaactggta aaccataatt
     6841 taccggctca ccaatattaa acagaactgg tgctagacca agtttagcaa cttttcgata
     6901 atgactgttt cttgaaaaaa ttaaaatagc aagtaccaat cctaatcctc caaaccagac
     6961 aaacgcccca aaagacccac ttgtccatat ataaggaatc ggttcacctt tttggaaagc
     7021 atccagattc gctaacatag caactccaaa cagcccttcc atgatgggag ccaatacatt
     7081 tcctccatgg agaccaaaaa accagaataa cttatttaaa aagatcatca gaataactgc
     7141 aaagaaactt tgagacaaac ctagtaatgg cgtttgtaac accttgtaaa cccaatcaat
     7201 caataagtaa ttgctaagta aatggaaaac ataagtcaag atggctacta taatacatcg
     7261 ccataaatcc tggaatgata gaagtgaacg gcttagcaat cgcaggggga actgaatctg
     7321 gtaacttgat tacccagttc tttttcatta ctttacagaa aataatagag gctaaaaatc
     7381 caatcatcat ggctgtaaag tagcctctgg cattaatatg gtttcctgga atcacattcc
     7441 caatagttac catcagattt ttaccatcaa atgctagatt atcaattcct tgtaagattt
     7501 gatctaattt cacatctcct acatttgcca aagggaaact ctttgtaact gtacttccaa
     7561 tcgaaatgac aaacgaagca agcgatacca aaccagcaga aactgtatca accttataaa
     7621 tcttagcgat attcactccc aagcaataga tgaacaataa ggaaacaatt ggtatacttc
     7681 ccttgaatac caaattattg atgtcaacaa gccactgaaa ggttttcgta atactttcta
     7741 ggtgaaattg ttgtggtaaa tccactagaa aagcatttaa taacaaagca atggaacctg
     7801 tcataataac aggcatagtc cccacaaatg aatcacgtaa agcaactaaa aacttctgat
     7861 tcccaacttt cattgcaatt ggagaaagtt tttcttgcat tttatccaac attgtattca
     7921 tagcaaattc ctaatttttt tcaaatcgtt cgtatacttc taccacttct ttcgccaagt
     7981 caacaaaggt cagactcgtc attaaatgat cttgcgcgtg taccatcaag aggctaattg
     8041 atgtttcttc cccctgtgcc tcttttgtca acatttctgt ttgagcctta tgcgcctgta
     8101 ataaggcagc attcgcatca gctaatcttc gattggcttt agagaaatca cctttttttg
     8161 ctgcctgaat agcctccata gcattacttt tggcttcccc accatacata attagcccca
     8221 ttacagattc taaattactt tcattcatag cattctcctc aatcttagtc taataaactt
     8281 tcagctaaat ctaagacttt agaaccattc atcattccgt aatctgtcat cggaataacc
     8341 gccacaggaa tctgtctatc ttttagtttt tcttgaaagt cccctagtaa atagcgaact
     8401 tgaggaccta aaagcaacac atttacttct tttgttgcta caatttcttc tgcttcagga
     8461 gctggaactg caaaaatttc tgcatccaac cccttatctt ctgctgcctt ttgcatcttt
     8521 gtcactagca gacttgtact catacctgct gcacacgcta acataattgt tactttagcc
     8581 atagcttact cctttatcac ctatttactg acctagccaa gcgagatact gtatgtctca
     8641 ctcctctaat tgccttgctc aatgcataaa tattatcgac tgttgccagt cccccatatc
     8701 ctgcgtcacc tatatgttga atatcaactc cacaaatttt atttctaagt gcaatttcct
     8761 tgatagtatc tgtatcagat gtttcttggc tagtaccaat agcactcagt actagcccac
     8821 ccttactatg aacgagatca acgacttcac gcaactcttg gtcatgaaag gctggaacgg
     8881 ttccaactgc tggaacaagt atcacatccg cacctgcttc caacaattgc tctgcgacag
     8941 aaagctctgc cacaggctca ttcactcctg ccccgtgcat cttacctgca ataatcaaac
     9001 cagaaaagtt ttccttagca gtttgaacag tcttaatgat ttctcgattg ctaactcctg
     9061 ttccaggatt tccagtcaaa cagacaaagt caaaacctaa ctcctctatt cgcttcaatg
     9121 tttcaacact agcaacacga cccgcaacaa tttcctgtgt ttcctctagc atctttgcag
     9181 atgggtcaat cggttccaaa tttacaccaa ttggacaagc aacaagctgg tgtaagcgat
     9241 gaataacatc atcacctgaa ctatccaaag cataaatttt aggctcaaaa acatcaacac
     9301 aattcaataa aatcatatca gctccaaaag ctctagcaat ttcagaatta gttatatccc
     9361 caacaaatgt ctcacgagta actacatttt cagatagaac aactctacct tcacttgcta
     9421 aaatactttg ttttaattct tcagcattca tctgtaatat ctcagatgga tttgcactaa
     9481 ttaaacgttt cattctcaat cctccaataa cttaaaccgt ttttcaatag ctattacaaa
     9541 tggtaaataa agtaagacat ccaaaacaat caatacaatt tgtaataatg aaccagaaat
     9601 acttcctgta gcaagtaaac cacttataac aggtggcata gtccaacttg gatctgtata
     9661 agttagcgga accaaacctg atgccattgc tccccacgct actagtaagt taaacattgg
     9721 agctaagata aatggaacta gtaacaaaat gttcaaaaca ataggaacgc caaacattgc
     9781 tggttcattt atattaaata atccaggtat aacagttata ggtgccaaag tttttagttg
     9841 tttactagct ttcttcttat gtgctaaata tcctaacgca agaactaaac ctatggttgc
     9901 accaccgcca cctatgaata caaaattatc cataaatacg ctagtaaaaa tatttggaag
     9961 agtttctcca gtttgataag ctactttatt tgcatctaga ttagctaacc ataacggttt
    10021 cataactgca ttaacaacat ttcctccgtg taatcctaca aaccaaaaac tactattaag
    10081 gaaaattaag ataagaagac caataacatt atttcctaaa agtccaagtg gacctcccaa
    10141 agctccttga gcaatttcat gaagattagg taaacttaat ttatctaaag ttgcataaac
    10201 aatcaaccaa ccaacaatag tcactgcacc aggaataatg gcactaaagc ttttagatac
    10261 tgctggtgga acaccatccg gcatttttat ctgtatatta tgatttataa accattggta
    10321 gatatagcca ttaatcaatc ctaaaatcat agcaacaaat aaaccttttg atgccatgaa
    10381 agcggtaggc attcctgctc cagcctctcc tgtaatgaaa ggcgtaactg taataaaaga
    10441 tgataatgac acaataccag caggaatacc atcaactttg tattgtctag ccataaagta
    10501 agcgatacca aaactagcta caagaccaag taatccaaaa ctactatcaa cacccttcca
    10561 taaatagtca gcaacaccaa tatcacctag atatttttcc catcctggaa taggaaaact
    10621 tgcaataacc attagtaatg aacctatcaa caataaaggt atagttagag taataccgtc
    10681 tcgaatagaa accaacgctt tattattacc caatctagcc gctactggaa gtaacttttc
    10741 ttgtaataat ttttcca
//
LOCUS       DBERDS010000057        10750 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.057, whole genome shotgun sequence.
ACCESSION   DBERDS010000057 DBERDS010000000
VERSION     DBERDS010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.057"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..277
                     /locus_tag="ACL73E_001790"
     CDS             <1..277
                     /locus_tag="ACL73E_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801717.1"
                     /translation="YLTTYNQKLSLRGMNYKLNHEELNNFDLLKKMFLKLMETDKIEN
                     DIFYLDGIKSILPLLSLDDRRNVLQHIQKQNNCPPPEIEELQRIIVN"
     gene            378..1256
                     /gene="truB"
                     /locus_tag="ACL73E_001791"
     CDS             378..1256
                     /gene="truB"
                     /locus_tag="ACL73E_001791"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGS0801718.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            1497..1799
                     /locus_tag="ACL73E_001792"
     CDS             1497..1799
                     /locus_tag="ACL73E_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGS0801719.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            1907..2545
                     /gene="udk"
                     /locus_tag="ACL73E_001793"
     CDS             1907..2545
                     /gene="udk"
                     /locus_tag="ACL73E_001793"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGS0801720.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            2673..4013
                     /gene="xseA"
                     /locus_tag="ACL73E_001794"
     CDS             2673..4013
                     /gene="xseA"
                     /locus_tag="ACL73E_001794"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGS0801721.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            3991..4203
                     /locus_tag="ACL73E_001795"
     CDS             3991..4203
                     /locus_tag="ACL73E_001795"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGS0801722.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIDLEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            4200..5075
                     /locus_tag="ACL73E_001796"
     CDS             4200..5075
                     /locus_tag="ACL73E_001796"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGS0801723.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            5068..5883
                     /locus_tag="ACL73E_001797"
     CDS             5068..5883
                     /locus_tag="ACL73E_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGS0801724.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     NLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            5876..6307
                     /locus_tag="ACL73E_001798"
     CDS             5876..6307
                     /locus_tag="ACL73E_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0801725.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            6314..7981
                     /gene="recN"
                     /locus_tag="ACL73E_001799"
     CDS             6314..7981
                     /gene="recN"
                     /locus_tag="ACL73E_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGS0801726.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMTEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            7983..8711
                     /locus_tag="ACL73E_001800"
     CDS             7983..8711
                     /locus_tag="ACL73E_001800"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGS0801727.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            8790..10613
                     /gene="lepA"
                     /locus_tag="ACL73E_001801"
     CDS             8790..10613
                     /gene="lepA"
                     /locus_tag="ACL73E_001801"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGS0801728.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         3197 a         1930 c         2609 g         3014 t
ORIGIN      
        1 ttacttaaca acttataacc agaaattatc tttacgaggg atgaattata aattgaatca
       61 tgaagaactt aacaattttg atttgttgaa aaaaatgttt ctgaaattaa tggagaccga
      121 taaaatagag aatgatattt tttatttaga tggcatcaaa agtatactcc cattattatc
      181 tttagatgac agacgaaatg tattacaaca tattcaaaaa cagaacaatt gtcctcctcc
      241 agagattgag gaattacaaa gaattatagt taattaaatt ttgtaaaaaa gagaataaaa
      301 ggtagacgac gcctcagtaa aaattggccc ggaaaaaagc gaagttcgaa gcactgaagg
      361 gggagtagaa agcaaaaatg aacggtatta tcaacttaaa aaaagaagca ggaatgacct
      421 cgcatgatgc ggtttttaaa ctgcgtaaga ttttgggaac caagaaaatt ggtcatggtg
      481 gaaccttgga tccggatgtg gtgggtgttt tgccgattgc ggttggcaag gcgacacgca
      541 tggtcgagtt tatgcaggac gagggtaaga tctatgaggg ggaaattact ctgggttatt
      601 ccacgacgac tgaggatgct agtggggaag tgatcgcaga aacccctgtt ttgtctccct
      661 tggatgaaaa gcttgttgat gaagcgattg ctagcttgac tgggcctatt acccagattc
      721 cccctatgta ttcggcagtt aaggttaatg gtcgcaagct ctatgagtat gcgcgtgctg
      781 gtcaggaagt ggagcgtcca gaacgtcagg tgaccattta tcaatttgag cgaacaagtc
      841 cgatttctta tgatggccaa cttgctcgat tcacttttcg tgtaaaatgc agtaaaggga
      901 cttacatccg tactttgtca gttgatttgg gtgaaaagct tggttatgcg gctcatatgt
      961 cccatttgac tcgtactagt gctgctggct tacaattaga agacgctctt gccttggagg
     1021 aaattgctga aaaagtagag gctgggcaat tagattttct ccatccttta gagattggga
     1081 caggtgacct tgtcaaagtt ttcctaactc cagaagaggc tacagaagtt cgctttggtc
     1141 gttttattga gctagaccaa acggacaaag aactggctgc ctttgaagat gataaattgt
     1201 tagccattct agaaaaacgg ggcaatctct ataagccaag gaaggttttt agctagatcg
     1261 tttaggaata aaaatcgggt gatagataac aattgcttga taaaacccca tactaatagt
     1321 agaatggttt tgggaattat aatattccaa ttgttgcgag ttgtaggtac tcaaataatc
     1381 tatatagaaa tttagaggtg tgaaatgaag caatttaaaa ttctttcaga taaatattta
     1441 gagtccatta caggttctgg tgggaactta ggcccaggat ttggtgtgat aattccatga
     1501 tgcgaaatga gtttcgagaa agggtggagc aacttcttca acaaaaagaa ataaatgaaa
     1561 atagtgagtt gagtcacctg tttcgtcttg ctatacaaaa tttagacaga aatgaaaaat
     1621 accaatcggt catggccaat ttgagtcaag ggttgtcact ttacctcatg acgcatcatt
     1681 accaggcacc taagtctgtc attgattttg gtttatggat tgccaaagct cctagccagg
     1741 aaagagggag actggctttc ttgcagatgc ttgctcaaac cctacagggc tttcgttaaa
     1801 actgtcgaac atcagaggga agactctggt gttttttgct gatgagacta taaattttgt
     1861 aaaaaatgtg atagaataga cgacggataa aataacggag gatagcatgc aaaatagacc
     1921 aatcattatt ggagtgacag gtggttctgg tggtggtaaa accagtgttt caagagccat
     1981 tttatcgcat tttcctgatg aaaagatttc catgattgag catgattcat actacaagga
     2041 tcagtctcat ttgacctttg aagagcgtgt caaaaccaac tatgaccatc cttttgcctt
     2101 tgatacagac ttgatgatcg agcagattaa ggaattgttg gcagggcgtc cggtggacat
     2161 cccgacctac gactatacag agcatacacg gagtagcaag acctatcgtc aggagcctca
     2221 agatgtcttt atcgttgagg gcattttggt cttggaggac aagcgtctgc gcgatttgat
     2281 ggatatcaag atttttgtgg atacggatga cgatgtacgt attattcgtc gtatcaagcg
     2341 tgatatggag gagcgtggcc gtagccttga tagcgttatt aaccagtact taggtgtggt
     2401 caaaccaatg taccaccagt ttatcgagtc aactaagcgt tatgctgata tcgtcattcc
     2461 tgaaggggtt agcaataccg tggctatcga cctgttgacg accaagattg caaagatttt
     2521 ggaagaagct cgaaacagca aataatcaca tgtggaggcc ttgcctcctt tttctatttt
     2581 tccctcataa tggtacataa atggagattt ttaggcatat ttttggtata ataataccca
     2641 tgaaagagca agtaaatgaa tagtaggtgg agatggaaaa gtatttatcg gtaacaactt
     2701 tgaccaagta tctgaaaatg aaattcgata aagacccata cttggaacgg gtctatttaa
     2761 ctggtcaagt ttccaacttt cgtaaacgac ctactcacca atatttctcc ctaaaggatg
     2821 accatgcagt tattcaagcg accatctggt ctgggattta tcagaaatta gggtttgacc
     2881 tggaagaagg aatgaagatc aatgtgattg ggcgtgtaca ggtctatgaa ccaagtggta
     2941 gctactccat catcattgaa aaagctgagc ctgatggggt tggggcgctt gcgattcagt
     3001 ttgaacaact taagaaaaaa ttgacagaag aaggcctgtt tcaagaacgc ttcaagcaag
     3061 ctctgcccca attttctaag agaattggtg tagtaaccag ccgtagtgga gccgttattc
     3121 gagatattat cacgaccgtc agcaggcgat tcccaggtgt tgacatcctt ctttatccga
     3181 ccaaggttca aggtgaaggg gctgcggagg aaattgctag aaatattgcg cgtgctaatc
     3241 aacgggacga tttggatttg ctcattattg gtcgtggagg tggttctatt gaggatctct
     3301 gggcctttaa cgaagaaatt gtggtacgag ctatttttga atctcgtttg ccagttatct
     3361 ctagtgtggg gcatgagacg gatgtgacct tggcagattt tgtggcagat cgacgcgctg
     3421 caacgccaac agcggcggct gaactggcaa cacctgtgac caagttggat gtattagctc
     3481 atttgcaaaa tcaggaaaaa cggatggtaa cggcagtccg aaatgttcta tctaagaaac
     3541 aagaggcttt gaaaaaatgc agtcagtctg ttatctttag acaacctgag cgcttgtatg
     3601 acggttattt gcaacgcttg gaccaactgc aactgcgttt gaaacaaagt ttgcgaactc
     3661 ggatttctga taacaaacaa ttagttcaag caagaactca tcaattagta caattatcac
     3721 ctgttaccaa aatccaacgc tatcaagacc gtttaggaca gttggacaag ctcttaggta
     3781 gccaaatggc gttagtttat gacgccaagg ttgctgaggc caagcgactt tcggaagctt
     3841 tgctcatgtt ggatactagc cgaatcgtgg cgcgtggtta tgctattgtc aaaaaagaag
     3901 agtccgttgt agattcggtt gagagtttga agaaaaaaga ccaagtaacg cttttgatgc
     3961 gagatggtca agtagaatta gaggttaaag atgtcaaaac aaaagaaatt tgaggaaaat
     4021 ctagcagaac tggaaaccat tgtccaaagt ttggaaaatg gtgaaattga tctggaagat
     4081 gcgattactg cctttcaaaa gggcatggtc ttgtcaaaag agctccaagc tacgctggac
     4141 aaggctgaaa agaccttggt caaggtcatg caagaagacg gaacagaaag tgattttgaa
     4201 tgaaaaagca agaaaaatta gctcttgtcg agtcggcttt ggaagatttt tatggagacc
     4261 agcagtttgc ctctagttta cgggagtctg ttctctattc tattcatgct ggtggcaagc
     4321 gtattcggcc ttttctcttg ttagaagttc tggaagcctt gcaggttacc atcaaacctg
     4381 ctcacgcgca ggtagctact gccttggaga tgattcatac agggagcttg attcacgatg
     4441 accttcctgc tatggatgat gacgattatc gaagagggcg gttaaccaat cacaagaaat
     4501 tcggtgaagc tatggccatt ttggctggag atgccttatt cttagactca tatgccttga
     4561 ttgcgcaggc agatttgcca agtcagatta aggtggactt gattgccaac ttatcccttg
     4621 cttcaggtag tctgggtatg gtggcagggc aagttttgga tatggagggc gaacaccagc
     4681 acttgtctct ggaagaactt cagactattc atgccaataa gactgggaag ttactagcct
     4741 atcccttcca agcggcagct attatagctg aattgtcacc tgaaatgcag gtgaagctga
     4801 aaactgtggg tgaattgatt ggacttgctt ttcaagtcag agatgatgta ctggatgtga
     4861 cagctagttt tgaggaaatc ggcaagacac ctcaaaagga tctgcaggca gaaaaatcaa
     4921 cctatcctgc cctgttgggc ttggaagagt ccattgcctt ttgtaaccaa accctggatc
     4981 aagctaatga aaaattagaa gaaattgccc agcagcttcc ctttgaaaca gaatcgattg
     5041 taagtgtagt agaaagtttg agaatcaatg gctaaggaaa gagtggatgt actagcttat
     5101 aaacaggggt tgtttgaaac gagagagcag gccaagcgag gtgtgatggc tggcctagtc
     5161 gtagcagtcc ttaatggaga acggtttgac aagccaggag agaaaattcc agatgacacc
     5221 gaattaaaac tcaaggggga gaaactcaag tatgtcagcc gtggtggttt gaaactggaa
     5281 aaggccttgc aggtctttga tttgtcggtg gatggcgcga ctacgattga tatcggggcc
     5341 tctactggag gttttaccga tgtcatgcta cagaatagtg ccaagttggt ctttgcagtc
     5401 gatgttggta ccaatcagtt ggcttggaaa ttacgccaag acccacgagt tgtcagcatg
     5461 gagcagttca atttccgcta tgctgaaaag actgatttcg agcaggagcc gagctttgcc
     5521 agtattgatg tgagtttcat ttcccttaat ctgattttgc cagccttgca ccgtgtcttg
     5581 gctgatcaag gtcaggtggt agcacttgtc aaacctcagt ttgaggcagg acgtgagcag
     5641 attgggaaaa atggaattat tcgagatgct aaggttcatc agaatgtcct tgaatctgta
     5701 acagctatgg cagtagaggt aggtttttca gtccttggct tggacttttc tcccatccaa
     5761 ggtggacatg gaaatattga atttttagcg tatttgaaaa aagaaaagtc agcaagcaat
     5821 cagattcttg ctgagattaa agaagcagta gagagggcgc atagtcaatt caaaaatgaa
     5881 taaaaaagaa agacttgaaa aaattagaag attggtgaca gattatcaaa tcggcacgca
     5941 agaagaaatt gtagaacatt tgaaagaagc aggtatcact gccactcagg cgacggtatc
     6001 ccgagatatc aaagagttag gtattgtcaa aattcctttg agagacaaca cttatgtcta
     6061 cgaattacca aaatcaatcg taaaaagtct gcaactggct gaagacaata tcgaatcggc
     6121 tgaattgatg gataagatga tcaatctcca agttattcca ggaaatacgg cttttgtaaa
     6181 agctcagtta atcgagactt ttgcagacaa gatttttagc tgtttgactg atgatagctc
     6241 gattttagtc attgccagaa gtggaagtct agcagaggaa atctttgaac aagtaaaaaa
     6301 ttggtaggtc tatatgttac ttgaaatttc gataaaaaac tttgccatta ttgaggctat
     6361 ttccctcaat tttgaaaagg ggatgactgt cctgactggt gaaacgggtg cagggaagtc
     6421 gattatcatt gatgccatga atatgatgtt gggagctcgt gcgacgacag atgttattcg
     6481 tcatggtgca ccaaaggcag agattgaggg gcttttctca gttgagaata gtcgtctttt
     6541 acaggaaatt tttgatgagc aaggtttaga attaggtgat gaaattatca tccgtcggga
     6601 aatcttgcaa aatggtcgta gtatcagccg tgtaaatggt cagatggtta atctgtctgt
     6661 tttgcgagct attgggcaac atcttgtaga tattcatggt cagcatgacc atgaggagtt
     6721 aatgcgtccc caactgcata tccagatgtt ggatgaattt ggtgatgccg ctttttggga
     6781 cttgaaagaa acctatcaaa cgagttttga tgcctatcgg aaaatgcgta agcaggttct
     6841 ggaagtcaag aaaaaccaac aggaacacaa ggcacgtatc gaaatgttgg aatttcaaat
     6901 gacagagatt gaggcagcaa acttgcaggc tggagaagac ttggctctca atcaagaacg
     6961 agataaactc ctcaaccaca aaaatattgc ggatacactg accaatgcct acagtatgtt
     7021 ggacaatgaa gatttttcaa gtctggccaa tgttcgttca gctatgaatg acatggaaag
     7081 tgtcgaagag tatgatcctg aataccgtga aatttcaagc tctctgtctg agacctacta
     7141 tgttttagaa gacattagca aacgtttgga agctatcatt gaggaccttg attttgatgg
     7201 caatcgcctc atgcaggttg agaatcgttt ggacctcctt catactatta ctcgtaagta
     7261 tggtgggact gttgatgatg ttttgcttta ttttgccaag attacggaag aatacaatct
     7321 cttgacaggc aataatcttt cgtctgagga catggaagca gagcttaaga agttggaagt
     7381 caatcttgtc aatttggcag gtcaacttgc ttctgctcgt cataatttgg ctcagcaact
     7441 cgaagctgag attaaacaag aactgcaaga tctttatatg gaaaaagccc agtttcaggt
     7501 tcgttttagt aagggaaaat tcagtcgtga gggaaatgaa atggttgagt tttatatttc
     7561 aaccaaccct ggagaagact ttaaaccctt ggttaaggtt gcttctggag gggaattatc
     7621 tcgtctcatg ttagccatta agtctgcctt ttcacgtaaa gaaggcaaga ctagcattgt
     7681 ctttgatgag gtggatacgg gagtttcagg tcgtgttgct caagctattg ctcagaaaat
     7741 tcataaaatt ggtcagtatg gtcaggtttt ggctatctcc catttgccac aagtaattgc
     7801 gattgcagat tatcaattct ttattgagaa gattagtaat gaccattcaa cggtttcgac
     7861 tgttcgtctc ttgacagtcg aagagcgagt ggaggaagtt gccaagatgt tggcaggtga
     7921 tgatgtgaca gaagcagccc tgacgcaagc cagagaattg ttgagaaaca gggagaaata
     7981 agatgacaga ttattatgta attggagatg ttcacggaaa agctgggatg ctggaagacc
     8041 ttcttaaaac ctgggatggt cagacccagt tgctctttct aggtgatttg attgacagag
     8101 gtgaggatag tcaccgtgtt cttgaaatgg tcaaggactt ggtggacaat caaggggcta
     8161 tctgtttgtc tggaaaccac gagtatatgt ttttgacttg gctagatgac ccagaagaaa
     8221 gttatgacca ttatcgtcgc aatggtggag atacaaccat taactctatc ctaggtcgtc
     8281 ccttggatgc accagttgat ggagtagaag atgccaagcg ggttgccgct gaagcggcag
     8341 acttggtcga attcattcgt caaatgccat ttgtagtaga gacagacaag tatatctttg
     8401 ttcacgcagg tattgatttg accttggacg actggcatga aacaacagat tataaaaaag
     8461 tatggcttag aaaaccattc cacggagctg aaaatcatac tggaaaaacc attgtcttcg
     8521 gtcatacacc ggtctatggt ttgttacagc aagaacgcgg tacatctgag ctttggacta
     8581 cagaagatgg caagattgga atggatggag gagctgttta tggtggtgtc cttcacggga
     8641 ttgtctttac agaccaagga atgacagaac accactttat cgaaaatgac ggctttgtcg
     8701 ctgaagatta gtactcttag cagggtatgg tcttgtcaaa atatcaaaaa caatttataa
     8761 taaatagata ccctgaaagg aagagaatca tgaacttaga agaattgaaa aaacgacagg
     8821 agaagatccg taacttctct attatcgccc atattgacca cggaaaatca actctagcag
     8881 accgcatttt ggaaaaaaca gagacggttt caagtcgtga aatgcaggcc cagcttttgg
     8941 atagcatgga gctagagcgg gaacgtggaa ttactattaa gttgaatgcc atcgagttga
     9001 attacactgc aaaagatggg gaaacttata ttttccactt gattgacaca ccagggcacg
     9061 ttgactttac ctatgaagtt tcacgttcgc tagctgcctg tgagggtgct attttggtgg
     9121 tcgatgcggc tcaaggaatt gaggctcaaa ctcttgccaa cgtttatctg gctttggata
     9181 atgatttgga aatcatgcct atcattaata aaattgacct gccggctgca gatccggagc
     9241 gcgtgcgtac agagattgaa gatgtgattg gtttggatgc cagtgaagca gttttggctt
     9301 ctgccaaggc tggtattggg attgaagaaa tcctcgagca aattgtagaa aaagtaccag
     9361 caccaacggg tgatgtgacg gcgccactta aggccttgat tttcgactct gtttacgatg
     9421 cttaccgtgg ggttatcctc caagtacgtg tcatggacgg agtggtcaaa cctggtgata
     9481 agattcagct catgagcaat agtaagacct ttgatgtgac cgaagtcggt atttttacac
     9541 caaaagcggt tggtcgtgat ttccttgcga ctggtgatgt tggttacatt gcggcgtcta
     9601 tcaagacggt tcaggatact cgtgtgggtg ataccgttac cttggcaacc aatcctgcgg
     9661 cagaaccatt acatggttat aagcagatga atcctatggt ctttgcgggt ctctacccaa
     9721 tcgaatcaaa caagtacaat gacctgcgtg aagcgcttga aaaattgcaa ctgaatgatg
     9781 ctagtcttca gtttgaacca gaaacatctc aggcacttgg atttggtttt cgttgtggat
     9841 ttcttggact tctccatatg gatgtgatcc aggaacgttt agagcgtgag ttcaatattg
     9901 acctcatcat gacagctccg tctgttattt acaaagttaa tttgaccgac ggtgagtcta
     9961 tggatgtgtc taacccatct gagtttccag acccaactaa gattgcgacc attgaagagc
    10021 cttatgtcaa ggcgcaaatc atggtaccac aggagttcgt cggagcagta atggagctag
    10081 ctcagcgtaa gcgtggggac tttgtgacta tggactatat tgatgataac cgtgtcaatg
    10141 ttatctatca aattcctctt gctgaaattg tctttgactt ctttgataaa cttaagtctt
    10201 cgacacgtgg ttatgcaagc tttgactacg aattgtcaga atatcgccca tctaagctgg
    10261 tgaaaatgga tatccttctc aatggagata aggtggatgc cctcagcttt atcgttcaca
    10321 aggactttgc ctacgaacgt gggaaactca tcgttgataa actcaagaaa atcatccctc
    10381 gccaacaatt tgaagttcca atccaagcgg ctattggaca caagattgtc gctcgtactg
    10441 atatcaaggc ccttcgtaag aacgtacttg ctaaatgtta tggtggtgac gtttctcgta
    10501 agcgtaaact ccttgaaaaa caaaaagctg gtaagaaacg catgaaatcc atcggatcag
    10561 ttgaagttcc gcaagaagcc ttcctcagcg tcttgagtat ggatgaagaa taagttatca
    10621 gaaatgcctt tccttgttca caggaaattt atataagaat caatagtaaa gcaggcttag
    10681 atggtctgct tttttagttt ttatactctt cgaaaatctc ttcaaaccac gtcagcgtcg
    10741 ccttaccgta
//
LOCUS       DBERDS010000058        10513 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.058, whole genome shotgun sequence.
ACCESSION   DBERDS010000058 DBERDS010000000
VERSION     DBERDS010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10513
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.058"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(31..1455)
                     /locus_tag="ACL73E_001802"
     CDS             complement(31..1455)
                     /locus_tag="ACL73E_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGS0801729.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2000..4279)
                     /gene="pulA"
                     /locus_tag="ACL73E_001803"
     CDS             complement(2000..4279)
                     /gene="pulA"
                     /locus_tag="ACL73E_001803"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGS0801730.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4391..6349)
                     /gene="ligA"
                     /locus_tag="ACL73E_001804"
     CDS             complement(4391..6349)
                     /gene="ligA"
                     /locus_tag="ACL73E_001804"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGS0801731.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6442..7620)
                     /locus_tag="ACL73E_001805"
     CDS             complement(6442..7620)
                     /locus_tag="ACL73E_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGS0801732.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7700..8563)
                     /locus_tag="ACL73E_001806"
     CDS             complement(7700..8563)
                     /locus_tag="ACL73E_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGS0801733.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8566..10467)
                     /locus_tag="ACL73E_001807"
     CDS             complement(8566..10467)
                     /locus_tag="ACL73E_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGS0801734.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3143 a         2328 c         1903 g         3139 t
ORIGIN      
        1 accaggaaaa caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac
       61 atttgtcatc gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac
      121 accaaggaat gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc
      181 tacttcaagt ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga
      241 ttgaaggccg aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg
      301 aatgattggt aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac
      361 ttggtcaaaa agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg
      421 agcctctttt tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc
      481 aataacaggt gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc
      541 ttcctgaagc aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat
      601 ggccgtgcaa cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg
      661 ttccaaatct gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat
      721 aggacgcata ccagctaaac gaccaatacg ttctccaata ggggttgaac ctgtaaagtt
      781 gatgaagttg acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt
      841 aatggtgttg aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag
      901 tccagaaatg gaaccttgtg ttggtggctt aaacatgacc acattccctg caatcaaggc
      961 aggtgcaatt ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac
     1021 gataccaact ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc
     1081 accaccttcc attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa
     1141 gtctgctgta cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc
     1201 aaggatagta ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata
     1261 agccgcacgt tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg
     1321 catagcctca tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt
     1381 gattggtgaa taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt
     1441 ctgatatctt gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt
     1501 tcagaaaatc acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt
     1561 caaagtatac tcaataaaaa taaaaaaaat ccactacatc aaggcgagac taatgtggtt
     1621 tgaagaaatt ttcgaagagc gtgaatgagt atcatctata gtaaaataaa aaaactgaac
     1681 aatttggttg gggacagtca aaccaatttc tcacaatgtt ttagaaacaa gggtgtgcta
     1741 ttccaatttc aggctactat aactgtcata gattgctgaa acaaagtcta ggtaaaagtc
     1801 ttcataataa aaagaccccc tatcaagtgt tcaaaaactt tgataggagg tcttgttttg
     1861 tgaaaatatt tatcaaattt tctatacaag tgagctgtta gccaggttct ttctattctt
     1921 tcaatttcaa tgaatggatt ttttaccaat actcataatt gggaatttgt ctgtgtaaaa
     1981 atagcgagat agatggtatt tataaaacac tcaagacagc tagactaata tcatttaaaa
     2041 cattatcttc ttttgagcga ctgttggtta ccaacatagc taaatttcct gcattttcaa
     2101 attgataggg ttctgattta gcattcacaa ctaccaagag gtgttctttg ccgtgaactt
     2161 catagataag gcagccgcta tgttcaatcg cagaatgcac aaagacatga tggtaaattt
     2221 catcatagct agagtaagaa aaggcaccag tttttgtctt caatcggatg acttgacgga
     2281 taaactcaat actgtcttga cgctcattaa tcaagttcca gttcacttgg ttcacactgt
     2341 caggagcatt atagctattc atcgcacgct ctctatcatc atgggtcaac tcaccatttt
     2401 caccagtcgc aaccagtttg gtacgaccaa attcttgacc gatttccata aaggccatcc
     2461 cctgcatgag cagattcatg gctgtggcag tttcgacctt gcgcatgatt tgctctgaac
     2521 tttggtctgg atgaagggtt gccaataaat cgtgaagatt gtaattgtca tgggcttcta
     2581 catagttaag cacctgattt ggatgtgtat aggttcctaa ttcacgactt cctaggattg
     2641 ctttagctag aattggctct gtcgcagcac cactgacaaa acctgacttg atagcaccat
     2701 aaacttctcc ccctttgaca gcatcgcgct gattgtcatt aaagaaacca atatttggca
     2761 tctggtaggc attgtccttc ttggccttat cataaggggt aagacctgtt cccatatccc
     2821 atccttctcc atagaggata atgttggagt cgatttcatc caagctttga cgaatcatct
     2881 gcatggtctt gacatcatga atccccatca agtcaaaacg gaagccgtca atattatatt
     2941 cctgcaccca gtatagaaga gaatcaatca tatacttgcg aaacatttcg tgttcactgg
     3001 ctgtttcatt tccaacaccc gttccattct ggaaggtacc atctggattc atacgataat
     3061 agtaatcagg gactgttgtt tggaatggtg catcaacaac tgagaaggta tggttataga
     3121 ctacatccat aatgactcca atacccgcat cgtgataagc ttgaaccatc accttcaaat
     3181 cacgaatgac ctgagctgga tcatctggat tagttgaaaa actagtttct ggcgcgttat
     3241 agttttgtgg atcataaccc cagttgtagg ttacatttcc atcctcatcg tattctttat
     3301 gacggtctgc aattggttgc aattgaacat aattgtagcc cagcttcttg atgtaatcaa
     3361 aagcagttga ctggccgtat tggttaactg ttccagcctg agcagcaccc aagaaagttc
     3421 ctcgaagatg ttcatctaca cccgatgtag gtgatttagt caaatcacga atgtgcattt
     3481 cacagataac tgccttacat ggattttcca agcgccaagt agcctccgaa ccgtgcttaa
     3541 cctcgaagtt ttcaacttgc ttttctacat ggctcagaat agctgaacgt ttgccatcag
     3601 ggctggtcgc gattgtataa ggatcacgtg tcagtgtttg gtgatgaggg aattggactt
     3661 gatactgata agtcttacct accaaatctt cttcaacatc caaactccag acaccgattg
     3721 tattgtcctt atgattataa gagtagctat tgcctctttt catctcaaaa gtcttccaaa
     3781 cgggtgcatc attagcagct gattcataaa cgacaacttg cacttctgtc gctgtaggtg
     3841 accagaggga aaaatgagcc tgattgtcct ctacacggca acccaattct ccttggtaac
     3901 cccaatgatg atcaaaacta gcactgttaa tggccttatc aaaggcaaaa ggattttgat
     3961 ttttatagaa aggactggca atagcaggat tttcagagta ataaatccta tcatcgcctt
     4021 ccaaaatcca gacctctgtc aataggggat agtgattaaa acggatagaa tattctttac
     4081 tagtttgacc tgtatgaacc acaaaattca agctttctat aacatgtgaa cttgggtgtt
     4141 caaagctaaa taaagctcca aaataatctt ctttgtaggt tagcaaatca attcgttgat
     4201 cctgactttt tacaaaggag caagtgtcat attctccatt cttacgatgg taatgaatgc
     4261 gcatagggta gttatacatt ttttattttt cctttttact ttgtttctat ttcactaata
     4321 aatttttgtc aatctcgtct caattaacag acatagtcat attctctaaa ctctgttttt
     4381 aaacgatcca ttacaaactt tctagccatg cctcatctct gacctggata ccaagttctt
     4441 gtgctttttg cagtttactt ccagcgtctg cacctaccac gacgaggtcg gtctttttag
     4501 aaacactacc tgtcactttg gcacccagac tttcgagttt acttttagct tctgagcgct
     4561 tgagtcgttc caattttcct gtcaatacca cggtcaaacc tgacaaggcc gcatccgcta
     4621 ctaccgtctg tcctttatag tccagattga ccccagtttc tttcaattct ctgagcagaa
     4681 tttcagagcc ttctgtcgca aaataagtct gaagactttt ggcaatcacg ccacctagac
     4741 tttcaatact agccacttcc tctgaatctg cctgatacag attttcaatt gaatggaaat
     4801 attgaagtaa aagctgacta gccttgcttc cgacatgacg aattcccaaa ccaaataaga
     4861 gcttctcggc agaattttcc tttgatgctt ggatagcctg atacagttta gcagcggact
     4921 tttccttaac cccctctaaa aggaggaaat cctcttcttg caaacgataa atatccgcca
     4981 catccttgac taaattagca gcaaaaagct tctcaacaat agatggacca aggcctgtaa
     5041 tattcatagc atcacgagaa gcaaagtgaa tcaagccttc catgatttga gcagggcaac
     5101 gcggattgat acaacgtagg gccacttcat cttcaaagtg caacaagtca gagttacaac
     5161 ttggacagtt tgtagggata tctagttttt cttcagaaac ccgtttggac tctaccacac
     5221 gtaaaacggc agggatgatg tcaccagcct tatatacaat gaccgtatcg tcttttcgga
     5281 tatctttttc agcaatataa tctacattgt gcagggtcgc acggctaaca gtcgtaccgg
     5341 caagttgtac tggtgttaga ttagcagttg gagttacaac accggtacgg ccaactgtcc
     5401 agtcaactga taagagttga gcttcttttt cttcagcagg gaacttgtag gctactgccc
     5461 actttggagc cttaacggta aaaccaagtt cttcttgact tgctaggtcg ttgaccttga
     5521 ttaccactcc atcaatatcg taaggcagat tttcccgttc ctgtcctact tcttggataa
     5581 aattccagat ttcatctatg ttttcagcca agattcgctt aggattgacc acaaaaccta
     5641 gttgttctag gtacttcaaa cccttttctt ggctatcacg agttgaaggg ctggcttctt
     5701 gatagagaaa cgttgcaaga ttacgcttgg caactactgc tgtatccaac tgacgcagag
     5761 ttcctgctgc cgcattacga ggattagcaa attcaggctc tccattttct tggcgcactt
     5821 ggttaacttg gtcaaaggaa gcgcgtggca tgtaacattc cccacgaact gtgatatcta
     5881 gttcttctgg caaagtcaaa gggatgtcct taacacgctt gaggttttct gtgatatttt
     5941 caccaattga accatctcca cgtgttaccc cagcaaccaa aatccccttt tcataagtca
     6001 gcgagataga taagccatcg attttcagct cacaaatata ggtcggatga gccacttcct
     6061 tacgaacacg cgcatcaaaa gcatctagct cctcacgtga aaaagcatcc tgcaaactat
     6121 aaagaggata ctgatgactg tatttttcaa aaccatctaa aaccttgcca ccaacacgat
     6181 gagtcggact gtctgctagc acttgctctg gataagcagt ttctaactcg accaactcac
     6241 ggtaaaggcg gtcatactca ctgtctgaaa ccgagggatt atcgctggta tagtactcag
     6301 tcgcatagcg attgagcaaa gcgactaact cattcattct tttattcata agaccatttt
     6361 accataaaac aagccctcct cacaaacgag aaggacggaa aaaacactta gtttgaaatt
     6421 atttttgaaa ctcaagcaac cttatatcaa tttttcaaaa tgagttcgaa cataaataaa
     6481 cgatatacaa gacaagatga taacaccact tccaattatc aggaaagaag agagatgtac
     6541 acttggcaag actgtcataa atccttttgc aataggcata aatagaatag ctaaggtaaa
     6601 aattgtactc agtactctcc caagaaattc gctctcaacc ttggtttgta cttgagtaaa
     6661 aaagtgaata ttaaaaatcg tcataaacaa ttcacaaact aaatttccag aaaaggaaag
     6721 aaaagttgga agtggtaatc ccatcataaa aactccgaca cctgtcaaag ccagtaaaat
     6781 caaaagatta taaatattag ctttaatttt actagctaga agagccccaa tgatggaacc
     6841 aatagccccc atagttaaaa tacttgcata ggctccttct gatccgtaaa gctgattcga
     6901 aaagggaagt agaaattcaa aagctgcaaa aaagaaatta acgctggaag ctaccagcaa
     6961 aaggaagaaa atttcttgct gatgccagat atagtgtaac ccatccttga tatctacaaa
     7021 aatatctctc ccagtaaaag cctttttctc ttgaactttt gcttcctctt ttggaaggaa
     7081 agccactaga acaaaagcaa tgaaaaaagt cagcgagtct agcagtagcg tcatatggag
     7141 acttgcaaac tgtaaaacaa ggaaggaaag aacaggagag ctaacaccta caacctgcaa
     7201 aaccagctct aggcgagaat tatagatcac aatctcatct ttctccacca cttcagttat
     7261 gatagcttta ttggctgtgc gagaaaaggc aaaagcaata gcctgcacaa tgttagcaac
     7321 aatcaaagcg ccaatcatcc agctatcatt ccttatgaaa gaaatagcca gacaaagaat
     7381 cccacaaaca agatctgccg tcattaaaat cttacgacga gaaaaacggt ctgaaataac
     7441 tccgccaaag ggattgacga gaatagatgt gacgagctca gaaatctgat acattcctaa
     7501 aactgtctgt cctatagtcc ccatagaagc caaccagaca ctatttccat aatcatagag
     7561 catatttccc attttattga tagccccacg gctaatcaac tgcactgcat agcgattcat
     7621 attaaagctc ctctcaaatt ttgaaactat tgtatcaaaa ccgaaaggag ctttttattt
     7681 tttcccttat ttgggaaaat taacttttga caaatttttc gtagtgttcc tgataatagg
     7741 ctacttgctc tggaagacct aacacatcaa aaatatgtat ggcctcttgc atctgcttac
     7801 agccttcttt acactgtcct ttttgatata aggcaaaacc ttttaaataa tggaaaacat
     7861 tacgctcata aagcttaata cctttgtcaa taatcttctc tgtataagcc tcaaaatagt
     7921 tggcattata aaaagaagaa tgctctaaac aatgctggta acaattgagg gccaaaatca
     7981 aaactaatct cttatggcga ctaatctctt ggtaaaattc ctccctctcc ataacttctc
     8041 taccaatccg agtgacatag tctacatcgt agaaactata gaggttaccg aaaagaatca
     8101 actcatacat ggtccattct tctgttttga agagataatc tgctacctta tccaaatcat
     8161 cctgcttcat atcataactc gcatctcttt gacaaatcag accttgtagc aaaatccagt
     8221 tcagctcaaa ataaagggga gtcgtcgaac tcttagactt ttcaagttgt tctctttgaa
     8281 gcttttgaaa acctgcaata tcgtttgaat agtaaagtgg gataatctgt gccatcatag
     8341 acacatgttc atgattgtga aaattccttg ccttatccat gaaattttcg attgttacat
     8401 gaatgttatc caaaatctca aagaaacggg agactgccag gtcagactcc ccaagctcaa
     8461 agcgagataa ctgagaggta gagcaggatt cgcctgctgc ttcctttaaa gaataatttc
     8521 cacttgttcg aaattcacga aatacttttc caagatgttc catctttaca cctgatctga
     8581 taattcttcc cactcaagca tagcttcttc ctgacgatgg ctgattttgt ccagctcagc
     8641 ctgtaattcc atgagtttgt cggcatcgtt tgtttccaac atttgttcag aaatggcttg
     8701 gctttgactt tctagctctt caatttcagc ttctagactt tcgatttgtc gcatgagttt
     8761 gcgaacttct ttttgacttt ctttctgggc ctgatagtca ttgactggac ttgcttcctt
     8821 tgcttgattg ctagttgaag cttcctcagt ctgactcatt tctgctgttg ctttcttctc
     8881 aacatagtag tcgtaatctc caaggtagag agttgaacca ttctcagaca attccaaaac
     8941 atgagttgcc acacgattga taaagtaacg atcatgactg acaaaaagca aggtaccatc
     9001 aaagtcaatc aaagcatttt ccaacacttc cttgctatca atatccaagt ggttggtcgg
     9061 ctcgtcaagg atcaggaagt tgttgttttc catagacaat ttagctaaaa gcaaacgagc
     9121 tttttcgcca ccagatagca tgccgactga ttttttaaca tcatctcctg agaaaaggaa
     9181 ggctccaaga cggttgcgga tttcaacttc tggtgtcagt ttgaaatcat tccagagttc
     9241 atccagcacc gtattacttg gtgtcagctt gctttgggtt tggtcatagt aaccaacctc
     9301 aacattagcg ccaaagcgct tttcaccttt gataaaagga atctggtcca caatagactt
     9361 gataaaggtt gacttgccga taccatttgg accaacgata gcgacagcat tcatcttacg
     9421 aagatctagg ttgataggtt gtgacaagac ttccccgtca taaccaatag cagtattttc
     9481 aacagtcaaa acaacattgc ccgacgtttt ttcagactgg aaggtcatgt tggctgcttt
     9541 cttgccagct tcaggcttgt ccaaacgctc cattttttct agttgtttac ggcgagattg
     9601 agcacgttta gtcgttgaag cacgaactag attgcgattg acaaagtctt ccagagcagc
     9661 gatttccttc tgttgctttt catagttttt tgcctcagta actagctttt gctccttcaa
     9721 ttcgacaaaa cgagagtaat tccccacata gcgatccaag gaatgcttgg tcaaatctag
     9781 cgtaattgtc gcaaccttgt ccaagaaata acggtcgtgg ctgacgataa tgagggcacc
     9841 gctatagttt accaagtaat tctctagcca ggcgatggtt tcaatatcca agtggttagt
     9901 tggctcgtcc aagaccaaga gattgggctt ttcaaggagc attttggcaa gtgccaaacg
     9961 agtattttga ccaccagaaa gctcagcaat tttcatctgc cacatagact cgtcaaactt
    10021 gaatccattc aaaatcgctc gaatatcagc ttcataggta aagccacctg cttggcgaaa
    10081 attctcagat aagcggtcat aatctgacat cagtttatcc aaatcctcac cagacttttc
    10141 acccatctcc agctccatct gacgcagttg tctctccgtc cgacgcaaat tattaaagac
    10201 atgaagcatt tcatcgtaga tggtattttc agactcaaaa cggctatctt gggctaggta
    10261 agacagagaa atatcttttt tcttattgat ttctccgcta gttggctcct cttctccaac
    10321 taaaatcttc aaaagagtag acttacctgc accatttttc ccaacaaggg caatccgatc
    10381 tcgttcatca acctgcaggt tgatattatc gaaaagaacc tctcctgcaa aagaacgttc
    10441 aattttatta gcttgtaaaa taatcataag agtagtatag catgtttccc taaggcattc
    10501 aagataatcg taa
//
LOCUS       DBERDS010000059        10373 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.059, whole genome shotgun sequence.
ACCESSION   DBERDS010000059 DBERDS010000000
VERSION     DBERDS010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.059"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(413..805)
                     /gene="rpsI"
                     /locus_tag="ACL73E_001808"
     CDS             complement(413..805)
                     /gene="rpsI"
                     /locus_tag="ACL73E_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGS0801735.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(825..1271)
                     /gene="rplM"
                     /locus_tag="ACL73E_001809"
     CDS             complement(825..1271)
                     /gene="rplM"
                     /locus_tag="ACL73E_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGS0801736.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1628..1945
                     /locus_tag="ACL73E_001810"
     CDS             1628..1945
                     /locus_tag="ACL73E_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGS0801737.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
     gene            complement(1990..2802)
                     /gene="folK"
                     /locus_tag="ACL73E_001811"
     CDS             complement(1990..2802)
                     /gene="folK"
                     /locus_tag="ACL73E_001811"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGS0801738.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(2845..3399)
                     /gene="folE"
                     /locus_tag="ACL73E_001812"
     CDS             complement(2845..3399)
                     /gene="folE"
                     /locus_tag="ACL73E_001812"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGS0801739.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3380..4702)
                     /locus_tag="ACL73E_001813"
     CDS             complement(3380..4702)
                     /locus_tag="ACL73E_001813"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGS0801740.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHFKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4704..5678)
                     /gene="folP"
                     /locus_tag="ACL73E_001814"
     CDS             complement(4704..5678)
                     /gene="folP"
                     /locus_tag="ACL73E_001814"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGS0801741.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5773..6480)
                     /locus_tag="ACL73E_001815"
     CDS             complement(5773..6480)
                     /locus_tag="ACL73E_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGS0801742.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6533..7951)
                     /locus_tag="ACL73E_001816"
     CDS             complement(6533..7951)
                     /locus_tag="ACL73E_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGS0801743.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            8141..8953
                     /locus_tag="ACL73E_001817"
     CDS             8141..8953
                     /locus_tag="ACL73E_001817"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGS0801744.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9292..10311
                     /gene="adhP"
                     /locus_tag="ACL73E_001818"
     CDS             9292..10311
                     /gene="adhP"
                     /locus_tag="ACL73E_001818"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGS0801745.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         3063 a         2339 c         2008 g         2963 t
ORIGIN      
        1 acccaaactc ttcacacaag agttctaact tacccattct atggaatctt gcattatcca
       61 taatatagta gattgaaact agaatagtac acctctactt ctaaaacatt gttagaattc
      121 gatttgacta tcctcggttt gtcctattct tatttcacct tactataaaa ataaggtaaa
      181 cttttcaaaa aaacacgaaa aaagcaccca tagggcaaac ctttgagtgc tttgaaacat
      241 tgatataatt gtattgatta gcgttttgag gcaactgacc ttgtcaggtt gcagccacat
      301 ttgtaagcaa ctaaagtcgc aacaactgtg tcaattgcac caatttagta agaaagtata
      361 aaaaaagaac accccgaaag gtgctctgta taagtatagt aattctttcg aattaacgtt
      421 tactaaattg tgatgcttta cgagctttct taagacctgg tttcttacgt tcaactttac
      481 gtgagtcacg tgtaagaagt cctgcgcgtt tcaatgaatc gcggaagtct gggtctactt
      541 gaagaagggc acgagcgata ccgtgacgga tagctcctga ttgaccagcg tatccaccac
      601 ctacaacgtt aacgaaaacg tcgtatgaac ctacagttga agtaactgcg aatggttggt
      661 tgatgacaag acgaaggtca gcatgtggga tgtactcttc aacatctttt ttgttaacag
      721 tgattttacc agttcctgga acaaggcgaa cgcgtgcaac agcgttttta cgacgtccag
      781 tacctgcata ttgtgcttgt gacatacttt atttgttcct ttccttagat aagtcctgaa
      841 atgtcaagaa cttctggttg ttgtgcagca tgagtgtgct cagctccaac aaatactttc
      901 aacttcatac cttgagcgcg tccaagtgta ttgtgtggaa gcataccttt aactgatttc
      961 tcaatcaaac gtactgcatt tttagaacga agttcacctg cagagatttg tttcaatcca
     1021 cctgggtggt ttgagtgagt gtagtagatt ttatcagttg cttttttacc agtcaattta
     1081 actttttcag cattgataac aatcacgaag tcacctgtat cagtgtgtgg tgtaaatgtt
     1141 ggtttgtttt ttccgcgaag tacgctagca actactgcag aaagacgtcc aagtggtaca
     1201 tcagttgcgt caactacgta ccatttacgt tcaacttggc ctggtttagc cataaatgtt
     1261 gttttgttca tgatttctcc tatatatagt tcgatttttg tttacggtga tgggtgttcc
     1321 ttcccatcga aaagtatttg gaaggttccg gggcctttca aatggggtaa acaataccgc
     1381 ctactatcat accaaatttc acccctaaaa gtcaatagat atgaaaaata tttttcggta
     1441 acttctcaaa gtaactgaaa gttatataat caagttaatt tgggaattta cctattaact
     1501 tcggtagatt tttgggaatt tttttcctta tttttccctg tagttaaaat ccttttcaaa
     1561 aaatcacctt ttcttgattt ttaatcctat ttgctgtatg ataagggaaa agaaagggga
     1621 cagagatatg gcttttacca atacccacat gcggtctgct agttttggca ttgttaccag
     1681 cttgcccgat gacatcattg actctttttg gtatatcatc gatcatttct taaaaaatgt
     1741 ctttgaattg gaagaagaac tcgagtttca attgcttaat aaccaaggaa agattacctt
     1801 ccacttttca agtcaacacc tccctacagc cattgatttt gactttaacc atcctttcga
     1861 ccctcgttat cccccaagag tactggtttt agacatgtac ggtagagaaa ctatcctcct
     1921 cccagaagaa aatgacctat tttaaaaact ctagccttca gttgcaagta actgaaaact
     1981 agagtttttc tattttttca aagcatcata caagttgcgg atcggttgtt ttaatgtcgg
     2041 atggataaaa tgaggcgcaa tttcctgtaa ggactcaagg acaaaaaggc gttccgctat
     2101 gtaaggatga ggcaatatga ggtcgtctgt ataaaggatc tggtcctcca caaagagcaa
     2161 gtccaaatca atcaaacgag gtccccaatg cacttctctc acccgtccca gctctgactc
     2221 aatggctaac aaggtttcta acaagtcttg tgctggtagc caggtttcca cctcaaccac
     2281 ttgattggca aagctatcct gctccactcc accccaaggc tccgtcgcta agacactgga
     2341 ctctttgaga atatagatgc cacgagctcg cagtttgtca atggcttgct tcaagtttgc
     2401 ttgtttatct cccatattgc ttcctagggc gataaaggct cgttgcttgc ggcgatgaat
     2461 ggttaccgag caagtatcta gtgacaaatg caccggtgcc caaggttttt tcagttccaa
     2521 cttcatttct tggacaagag gataagactc aaaggtacgt tccaccagtt tataggctac
     2581 cgtttcaatc aaatcttcac tcgtttcctg aaaccaagtc gtccactgct gacataattc
     2641 tccgtaatgg acagaggctg ttaaatccaa gtctgtagct gccttggtca tatcatagga
     2701 taggatggct gaaacgacaa atttctgccc caattctttc tcactaggaa aaagaccatg
     2761 ataggcaaac atttccaaat ccttaatctg cagttgatcc ataatgattc ctttctagaa
     2821 aaatccgctt gaagcggatt ctttttatag ccccattaaa cgataagctt ggtcgcggag
     2881 gtccttatct gtttcaaata gaccacgagc tactgtcgtc aaggttgcag tgcctggttt
     2941 tctaacacca cgcatactca tacacatatg ttccgcctca atgacaacaa aggctccttt
     3001 agcacctaga tagtccatca aggcatcggc cacttcgata ttcaaacgtt cttgaatttg
     3061 tggttttttc gaataaactt caaccgtacg ggctagctta gacaagcctg ccacacgacc
     3121 atctggaatg taggcaatgt gcgctctacc ataaaatggc aagaagtggt gttcacacat
     3181 ggtatggaaa aagatatcct tttctaccac catattatcg tcaataattt caaaggattt
     3241 tgacaaatgt tcctctgctg tttgaccaag acctgaaaaa atctcttgat acatacgggc
     3301 tacacgagca ggtgtttcct gcaagccctc gcgattagcg ttctctccta cagcctcgat
     3361 aatcattttt acagctgctt caatcttttg tgtatccatt ctcgttcttc ctctccatca
     3421 gataggccct cacttggctc aagaaataca aggaacctgt gacaatccta actgtttgtt
     3481 tctcttcttt tttatctgtc aaattctgct ctagaaaatc atgccaatct tggtagctga
     3541 gatttctaga cttagctgcc tctttcagca cgctttcatc cgtcgcccga ctatccgcaa
     3601 aatgtgttag agtaagctcg gtatctggca tggctcccag caagtccaac atatcctcca
     3661 aggctttggt tttgatacaa gtgaagagga tttccttatg ataatccgca aaacgttctt
     3721 gcaaggttac caacaaggcc ttgatagcat ggggattatg ggctccatcc aaaatcatca
     3781 agggatctct tgacacgatt tccaaacgcc ctggccaact tgtttcttcc aaggcttgac
     3841 caagaaagtc attgcttgct agctctcgac catcttcttg acaaaaagta tcaagtaaag
     3901 ctatggccat cccagcattc tctatttggt acaaaccaag caggctagtc tggaagcgac
     3961 cttgtctgac agcacttgta tagtcaaaga cttcccctgt caccacactt tcttgatgac
     4021 gaacctgata atctgtcccg taggcaagtc tcggcgcatc tttcccttcc gcaatgcggt
     4081 caatcacagt caaggcttct ggagcaatac gccctgttac caagggtatc ccttgtttga
     4141 taatacctgc cttctgctct gctatggcct ccaaggtgtc accaagtagg gccacatgat
     4201 ccaagccaat agttgtaatt cctgtcaaaa tgggctgaca gacattggta ctatccaaaa
     4261 gtccacccat gccaacttcc atgatggcca catctacttg ctctgaggca aagtagtcat
     4321 aggccagggc tgtgataatc tcaaactcgg ttgtgccctg taaattggcg accgcttctc
     4381 cctccagcaa agactgatag tctgccatga gagcttctag cctcgcttct gagatcgatt
     4441 ccccattgat gctaatctgg tctgtgtaat gaatgagata gggcgagcta aacacgccaa
     4501 ctctcagccc tagcttttct agcatctttt tcaaaaaagc aatagtcgag cccttgccgt
     4561 tagtccctcc gatatggagg accttgagtt tgaaatgggg attgccacgc aaagctaaca
     4621 gttccaccat tcgttccaat ccaaaatgcg gttgatccgt ccggtagtta gcaatccact
     4681 gattgttttc aatttctttc atcttattta tattgtttta aatctaaatt ttccgcttca
     4741 tcagccagac gaatggcaga ggcaatttca actgccatcc tgtgactagc tacgtcatgc
     4801 acgcgcacca cttctacacc ctgtctcgca gcgatactag ttacatgagc cgaagccgtg
     4861 tcccgatttc ggaaaccaag ctctgtctca ggattgactt caaacccact ttcttcaagg
     4921 atattgatga caaatcgctt gcgcgacact ccgagaaaga ttggatagcc cttctgatgt
     4981 agtttatcca ggtcccgtaa aaggaggaga ttttctttct tggtcagacc aaagccaatt
     5041 cctggatcca acaggatatt ttctggtgta ataccagctt ctgccgctct cgctagtgct
     5101 cgttcaaaga aagccaccat caagtcttcg attggcaatg tttcaaagtc agctaactct
     5161 ttttctgtaa aggtttgacc aaagccaaaa tgagggaaga taagcgaact aggatgttga
     5221 ggtcgagcca tgactggatt aaacatgatg actactttcg ctccagcttt agcaaccaca
     5281 tgggccattt tttcatcgcc catgagacca gtgatatcat taactagatt ggcaccagca
     5341 gccaaagcag cctctgccac ctgacttttc caagtatcga tagaaataag gacatcactt
     5401 tccttgcgaa tcgctttgat cactggaaca acacgctgga tttcctcttc tatctcaaca
     5461 tagctactgc ccggccgagt cgattctccg ccgatatcga gcatactggc tccttctgct
     5521 atcaatttac gagcctgctg gagtgcctgc tcaagagcaa aaaattgacc accgtccgaa
     5581 aaggagtctg gggttacatt gataattccg caaataactg tctttgcatg attggcttta
     5641 cttgacatat cggtcactcc ctcaaggatt ttcatcatat tatttttcta ttttaccata
     5701 aaaagaaaaa gatggacacg attgcattca tctttcccta gtagaaagag gtcggttcct
     5761 acataaaaac ttttacacag aaattcctaa tgtccgactc ataatcacca caagagccaa
     5821 caaacagaaa gcaatcccat taacaatcat gtgaagcaag atcgacattt ccaaacgttg
     5881 ggtcttgtag gccgtccaag atagaactgt cgacatacct ccataaatca ataaagaagg
     5941 taaattactt ggttgatgca ataaagcaaa cacaatcgta ccgactacaa atcccaagtt
     6001 ctccttgcct cggaaaatct ttttaggaac aatcccacgg cacaagattt cctcacaaat
     6061 tggagcaagc aaggctagca agaagaagct agaaatcaga gaactattct gaaccatatc
     6121 gttaatctga gactggttag ctgttgtcgt ctcatttgac agttgcaaca agatagaacc
     6181 aagtatattt gacccgacaa taactaaata actcaagccc aaacgtgcca aatctttagc
     6241 tctaaaaaaa gaaaaattaa aactagctaa cttggtttta cgagctccca taataaatag
     6301 agccagaacc acaattgaaa ggccagtaac tatcagccct gactgtagca gggctacttc
     6361 ttttaaagtc aaaatagagg taaccactag gggaacctga tataaaagga cggcaagtaa
     6421 aaagaccaaa atccagcctg cacgattcaa caattctttc cacatatttt tctctttcat
     6481 cacctatctc ctttgtatta aaaaaggggg gaaatccccc tgggtcattc tattataagg
     6541 ccatgctgat gtagttaagg ataaacaagg catccaaaat ccaaatcatg gcatgaacat
     6601 ctttaacttg acctttgaca agcttagtca aagtgtaagt caagaaacca actgcaatcc
     6661 cttgagtgat agagtagctg aatcccataa agatagatgt gaagaaggca ggaactgctt
     6721 cagacatatc atcccaatgg atatttttca agctaccaag catcataatc ccaacgataa
     6781 tcaagattgg agctgtagcc gctgttggta cgatcgctag aagtgggcta aagaagcttg
     6841 aaatcgcaaa acagatagct acaaccaagg ctgtcaaacc agtacgtcca cctgcaccga
     6901 taccagcagc agactcaaca taagtcgtta cgtttgaagt acctgcaatg gcaccgactg
     6961 tcgttccaat caaatcagag taaagagcct tatccaattt ggctgattgg tgattttcac
     7021 catttgtcgc tacaatacca actttttcac ctgtaccgat caaggtacca attgtgtcaa
     7081 aaatatctgt caatgagaag gcaagaatgg ccatcagagt ttcaggcaag cgagctgtat
     7141 ctgaaaccaa agctcccaaa ccttctgaac caagagctgc accaaagatt gtcttcaaat
     7201 cttcaaaagc tgcaccaaca tggttattag caaaatcgat actagacaaa tcaaccaaac
     7261 caactgcaat agcaagaaca gttgttgtca agatagagag aataattccc cctttaatcc
     7321 ctttgatgac aaagaagata gtaatggcaa gtcctgcaag agccactaaa acagctggat
     7381 tattaaagct gaccaatcct ggaactgctg aagagtttgc tgcaatcgtt gcttgagctt
     7441 tgtcagcccc ttctcctaca acagtatagt tgcctggatc aatcgtgaat ttcaaaagtc
     7501 cagcattctt aatccctaca taggcaagga agacaccgat accagctgaa atagctgagc
     7561 gaagagcatt gggaatcgat tcaatgatca ttttacgaac atttgtcaag gtaataatca
     7621 atgaaataat cccacagatg aagaccatag ctagggcttc ttgccaagaa taaccaagcc
     7681 cgaatacaac tgtaaaggta aagaaggcat tgagtcccat acctggtgct tgggcataag
     7741 gtaagttagc ataaaaagcc atcatcaagg tacccgctac tgcaccaata atcgtcgcta
     7801 ggaagacgcc ctgagcaggc attcctgttt gtgaaagtat ttgtgggttt acaaagagaa
     7861 tatagctcat tgcaaagaaa gttgttaaac cagcgagaac ctctgtacga acgtctgtac
     7921 cgttctcttt tagtttaaat aatttgtcca tcatcaatct ccttttaatt tttacgaaca
     7981 ataatagaat tatatcattt atcattcact ttttcaatgt ctttgtttga tttgtttaag
     8041 aaattaatcc aatttcattt tttgtttgga atctgctttt ctgcctgctt tctgttataa
     8101 tagaagacat cttatctgaa aacacactag aaaggtccat atgacgaaaa aaattattgc
     8161 agttgacctg gatggaaccc tgctcaactc agacagtcaa atttctgact ttaccaaaag
     8221 aaccatcaaa aaagttgctg aaaaaggcca tcaggttatt attacgacag gtcgccctta
     8281 ccgtatgtca aaagattttt accgtgaact gggcttagac actcctatga ttaacttcaa
     8341 cggatccctt actcatttac cagaccaagt ttgggatttt gaaaagtgtt tgactgtaga
     8401 caaaaaatat ctgctagata tggttcaacg ttcagaggac attcaagccg attttatcgc
     8461 tggagaatat cgtaaaaaat tctacattac aaatcccaat gaagaaattg ccaatcccaa
     8521 actatttggt gtagaagctt tccagcctga agatcaattc cagcctgaat tggtgaccaa
     8581 ggaccctaac tgtatcctct tgcagaccag agccagtgac aaatatgcct tggcaaaaga
     8641 aatgaacgcc ttctaccagc atcaactttc tatcaatacc tggggaggtc cgctcaatat
     8701 ccttgaatgt accccaaaag gtgtcaacaa ggcctttgct ttggactact tgctcaagat
     8761 aatgaatcgt gacaaaaaag atttgattgc ctttggagat gaacacaatg ataccgaaat
     8821 gctcgctttt gctgggaagg gttatgccat gaaaaatgcc aatccagagc tactccctta
     8881 tgcagatgag caaatttccc ttaccaacga ccaagatggg gttgccaaaa ccctacaaga
     8941 cttattctta taacctatac tgatactcaa tgagaatcaa agagcaaact aggaagctag
     9001 ccgtaggttg ctcaaagcac tgctttgagg ttgtagatga agctgacgtg gtttgaagag
     9061 attttcgaag agtatgacca gcttgcaagc tggtctttgt gctcttttca cagtctcatc
     9121 aaccagttaa tcgattgttc tactttttgt ctccaaaacc ttggaaaagg cttccttttg
     9181 tgatatactt cacatataaa tacaagagag ctcgtcacac tcgactctgt tgacaaaaaa
     9241 tcaatccagt cccgttgtcc ctgttctcgg tcaatatcaa ggaggatagc tatgaaagct
     9301 gttgttgtaa atccagaaag cactggtgtt gctattgaag aaaaagtact ccgtccactt
     9361 gaaactgggg aagcacttgt agaagttgaa tactgtggcg tttgccacac cgacctccac
     9421 gttgctcatg gtgactttgg tcaagtccca ggacgtgttc ttgggcacga aggtatcggt
     9481 atcgttaaag agattgctcc agatgtgaaa agccttaaag tcggtgaccg cgtcagcgtt
     9541 gcttggttct ttgaaggatg tggcacttgc gaatactgta caactggtcg cgaaaccctt
     9601 tgccgtacag tgaaaaatgc tggctactca gtagacggtg gtatggctga acaatgtatc
     9661 gtaactgctg actatgctgt caaagttcct gacggacttg atccagccca agcttcttct
     9721 atcacatgtg ctggagtaac aacctataaa gctatcaaag aagcaaaagt tgaaccaggc
     9781 caatgggttg ttctttacgg tgctggtgga cttggtaacc tcgctgttca atacgctaaa
     9841 aaagtattca atgctcatgt tatcgcagtc gatatcaaca atgacaaact tacccttgca
     9901 aaagaagtag gcgctgacat tgtgattaac ggcctcgaag ttgaagatgt agctggactc
     9961 attaaagaaa aaactgatgg aggagctcat tcagctgtcg taactgctgt gtctaaagtt
    10021 gccttcaacc aggctgttga ctccattcgt gctggtggtc gcgtcgtcgc tgttggtctt
    10081 ccttctgaaa tgatggaact cagcatcgtt aaaacagtcc tcgatggaat ccaagtcatc
    10141 ggttctcttg tcggaactcg taaagactta gaagaagcct tccaatttgg tgcagaaggt
    10201 ctggtagtcc cagttgttca aaaacgtcca gtagaagatg ctgttgccat tttcgacgaa
    10261 atggaaaaag gccaaatcca aggacgtatg gtactcgact tcacccacta atttaataga
    10321 aacctatttt aaaagttgga agcttcttcc aactttttta tattaaattt taa
//
LOCUS       DBERDS010000060        10331 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.060, whole genome shotgun sequence.
ACCESSION   DBERDS010000060 DBERDS010000000
VERSION     DBERDS010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10331
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.060"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="ACL73E_001819"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="ACL73E_001819"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGS0801746.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYVQANLDSSQD"
     gene            1317..2021
                     /gene="yycF"
                     /locus_tag="ACL73E_001820"
     CDS             1317..2021
                     /gene="yycF"
                     /locus_tag="ACL73E_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGS0801747.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="ACL73E_001821"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="ACL73E_001821"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGS0801748.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="ACL73E_001822"
     CDS             3365..4174
                     /locus_tag="ACL73E_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGS0801749.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /gene="relB"
                     /locus_tag="ACL73E_001823"
     CDS             4265..4507
                     /gene="relB"
                     /locus_tag="ACL73E_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGS0801750.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="ACL73E_001824"
     CDS             4509..4763
                     /locus_tag="ACL73E_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGS0801751.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5553
                     /locus_tag="ACL73E_001825"
                     /pseudo
     CDS             4810..5553
                     /locus_tag="ACL73E_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(5854..6840)
                     /locus_tag="ACL73E_001826"
     CDS             complement(5854..6840)
                     /locus_tag="ACL73E_001826"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGS0801752.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7034..9502
                     /gene="gyrA"
                     /locus_tag="ACL73E_001827"
     CDS             7034..9502
                     /gene="gyrA"
                     /locus_tag="ACL73E_001827"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGS0801753.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9502..10245
                     /gene="srtA"
                     /locus_tag="ACL73E_001828"
     CDS             9502..10245
                     /gene="srtA"
                     /locus_tag="ACL73E_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGS0801754.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3211 a         1750 c         2302 g         3068 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgt ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggtcccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg tacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacgaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tgggcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg tgtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 actaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt tgaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cacaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattattaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgctccctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagca tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtggat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg caagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgat aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagagatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttgggcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaataa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg acctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacccaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagattt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgttttat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaac caatgttttg gaagacccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tatcgtacaa attgtagatg atgaattagt tgttgctact ctagaagttg
     4741 gtcatcggag agatatttat tgaattcaag ctgagtaata acagtataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggttattt gcagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgac tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatat ttttgattta
     5041 ttggctattc tccctttaaa tgctattttt acagtgtttc gattaggacg tatcttccgc
     5101 ttagcaaggc tgacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaactag aaagaaaaat tagtagattc ttacgaacaa atggattgat ttatatcttg
     5221 tatgttaata tctttattgt tctagtaggg agttcgattt tatccgttgt tgaagaaaaa
     5281 tccttctcag atagtctttg gtgggctctt gtgacagtaa ctactgttgg ttatggtgat
     5341 attgttccag tttccctttt tgggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgctaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actcaaagac gaattatcga gctaaagaat attaatagag
     5521 aaacaatctg aaaaaatcga agaactacat tgaatgataa aagacttagt tgaaaaaata
     5581 tcataaaggt gagacaaaat aaaacttgat tcgaggagaa atcaagtaag ttttgacaca
     5641 atagaacgca tattatcagg tataaaaact tgatactatg cgttttatag agaaataaaa
     5701 taaaatctga acaaatcaat taggaattta aagcatttta taacaacgtt ttagagtaat
     5761 ggggtgctat ttcaacttca acctactata atacagaaaa aaatacagaa aaaaacaact
     5821 ccctgatgat tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc
     5881 tggatttttc catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt
     5941 ttgagtttct gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac
     6001 aacagctggt tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga
     6061 aagtggaagt actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac
     6121 tgcgataccg tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac
     6181 accttcgaac aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc
     6241 ttcaaggttt acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg
     6301 ttcacccatg atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc
     6361 ttgacggaaa cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa
     6421 accagagaat ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa
     6481 gatacctttg aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt
     6541 tttacctaca aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgattac
     6601 aacaaggtca gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt
     6661 gaaggcaagg gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg
     6721 aatttcgata attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga
     6781 tgaacctaca gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat
     6841 tgttttaaac atctccttaa ttttattagg ggattttccc tagacaactt cattctatca
     6901 cttttaaaaa actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt
     6961 ttagaggctg aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat
     7021 gaggcattta ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa
     7081 ggcaagtttt atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg
     7141 agatggctta aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac
     7201 cccagacaaa ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca
     7261 cccacacggg gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta
     7321 ccgttacatg cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc
     7381 cgctcaacgt tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat
     7441 caacaaaaat acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt
     7501 cttgccagcg cgttttccaa accttttggt taatggagca actggtatcg cggttgggat
     7561 ggcaaccaat attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat
     7621 ggataatcct gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc
     7681 aactggtgct cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg
     7741 ttcgattgtc ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgtat
     7801 cgttgtaaca gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg
     7861 cttggttcag gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga
     7921 aggtgttcga tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa
     7981 cctcttcaaa atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa
     8041 tggtataccg aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa
     8101 agaagtggtt gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat
     8161 cttagaaggt ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc
     8221 tagtgaaacg gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg
     8281 tcaaagtcaa gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa
     8341 gattcaatct gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc
     8401 taagcctgaa cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt
     8461 ttctgataaa cgccgtacag agttgatggt tggacagatc ttgagtctcg aggatgagga
     8521 cttgattgaa gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt
     8581 ggatcaggac gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt
     8641 gaaagatgat gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt
     8701 cttcacaaac aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg
     8761 gactgccaaa gggctaccag tagtcaatct cttgaaattg gatgaagatg aaagtattca
     8821 gacggttatc aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg
     8881 tcacggtatt gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct
     8941 caaagcgctg aatttaaagg atgaagatga gttaatcaat gtcttgttga cagaaggaga
     9001 tatggatatt atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt
     9061 tcgtggtatg agccgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac
     9121 agttgttggt gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg
     9181 atatggtaag cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat
     9241 gcagacagct aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg
     9301 tgatgaggat ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa
     9361 tatttcacaa acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc
     9421 tcagatagtg actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa
     9481 cgaaacagaa ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa
     9541 aatctgctga caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt
     9601 aatactcaaa ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag
     9661 gtatcaaaag aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct
     9721 gtcaaagcta tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca
     9781 gttattgggg gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt
     9841 gataatgtta atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa
     9901 ggaaattata gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta
     9961 ttttctcctt tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa
    10021 gtttatactt atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt
    10081 gatgatagag atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca
    10141 gaacgtatta ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat
    10201 gaaatcctaa cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa
    10261 tcatggattt cactgatttt ttaagatttt cataaaaata tagtaaaatg aaataagaat
    10321 aggacgaatc g
//
LOCUS       DBERDS010000061        10039 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.061, whole genome shotgun sequence.
ACCESSION   DBERDS010000061 DBERDS010000000
VERSION     DBERDS010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.061"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..339
                     /locus_tag="ACL73E_001829"
     CDS             <1..339
                     /locus_tag="ACL73E_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0801755.1"
                     /translation="NCLSETTDKNWHKSDRIFVTNIGKPVHSSILSKSLQRANERLKK
                     PIPKHLPPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSIYTQVTKNMKDEAIN
                     VLDKVMKKIF"
     gene            complement(477..1781)
                     /gene="eno"
                     /locus_tag="ACL73E_001830"
     CDS             complement(477..1781)
                     /gene="eno"
                     /locus_tag="ACL73E_001830"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGS0801756.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            1945..2391
                     /locus_tag="ACL73E_001831"
     CDS             1945..2391
                     /locus_tag="ACL73E_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGS0801757.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2388..3503)
                     /locus_tag="ACL73E_001832"
     CDS             complement(2388..3503)
                     /locus_tag="ACL73E_001832"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGS0801758.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGYQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3512..3841)
                     /locus_tag="ACL73E_001833"
     CDS             complement(3512..3841)
                     /locus_tag="ACL73E_001833"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGS0801759.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(3786..4157)
                     /locus_tag="ACL73E_001834"
     CDS             complement(3786..4157)
                     /locus_tag="ACL73E_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGS0801760.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4216..5649)
                     /gene="glgA"
                     /locus_tag="ACL73E_001835"
     CDS             complement(4216..5649)
                     /gene="glgA"
                     /locus_tag="ACL73E_001835"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGS0801761.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5646..6785)
                     /gene="glgD"
                     /locus_tag="ACL73E_001836"
     CDS             complement(5646..6785)
                     /gene="glgD"
                     /locus_tag="ACL73E_001836"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGS0801762.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAEMFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GKGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6775..7917)
                     /locus_tag="ACL73E_001837"
     CDS             complement(6775..7917)
                     /locus_tag="ACL73E_001837"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGS0801763.1"
                     /translation="MKNKMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGAVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(7907..9835)
                     /gene="glgB"
                     /locus_tag="ACL73E_001838"
     CDS             complement(7907..9835)
                     /gene="glgB"
                     /locus_tag="ACL73E_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGS0801764.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFVERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3046 a         2219 c         1776 g         2998 t
ORIGIN      
        1 aattgtctaa gcgaaacaac cgataagaat tggcacaaaa gcgaccgtat ttttgttacc
       61 aatataggaa aaccagttca tagttctatc ttgagcaagt ctctccagcg agcaaacgaa
      121 cgccttaaaa aaccaattcc caaacatctg ccccctcaca tcttcagaca caccactatt
      181 agcatcttat cagaaaataa aattccttta aaaacaatca cggacagggt tggtcattcc
      241 gactctgaag tcactacttc catctacacc caggtcacaa agaatatgaa agatgaagca
      301 atcaatgtac tggataaagt tatgaaaaag attttttaaa aagttttgtc ccttttttgt
      361 cctctaaata caaaaatagc ccttcggata aaatccgagg ggctagaaac gttgttaaat
      421 caacggccga acttttgaat ttcatggttc gggataaaat agttcactga actattttat
      481 tttttaaggt tgtagaatga tttcaatcca cgatattcag ctacttcacc aagttggtct
      541 tcgatacgaa gcaattggtt gtatttagcg atgcggtctg tacgtgaaag tgaaccagtc
      601 ttgatttgtc ctgcgttagt tgcaactgca atatcagcga ttgttgaatc ttcagtttca
      661 cctgaacggt gtgatacaac agcagtgtaa ccagcttctt tagccatttc gatagcttca
      721 aaagtttcag taagagtacc gatttggtta actttgataa ggattgagtt agcagcacct
      781 tcttggatac cacgtgcaag gtagtcagtg tttgttacga agaagtcgtc accaacaagt
      841 tgtactttct taccaagacg ttcagtaaga gctttccaac catcccagtc gttttcatcc
      901 ataccatctt caatagtgat gattgggtat ttgttaacca attcttcaag gtagtcgatt
      961 tgttctgcag atgtacgaac agcagcacct tcaccttcaa atttagtgta gtcgtaaact
     1021 ttacgttctt tatcgtagaa ttctgatgaa gcacagtcaa atccgataaa tacgtcttta
     1081 cctggtacat atccagcagc ttcaatcgca gcaaggatag tttcaacacc atcttcagtt
     1141 ccttcgaaac gaggagcgaa tccaccttcg tcacctacgg cagtttccaa accacgtgat
     1201 ttaaggattt tcttaagagc gtggaagatt tcagcaccgt aacgaagggc ttctttaaat
     1261 gttggcgcac caactggcaa gatcatgaac tcttggaaag cgattggagc gtcagagtga
     1321 gaaccaccgt tgatgatgtt catcattgga gttggaagaa ctttagtgtt gaatccacca
     1381 agatagctgt aaagtgggat ttcaaggtag tcagcagcag cacgagctac agcgatagac
     1441 acaccgagga ttgcattcgc acccaattta cctttgttag gagtaccgtc aagtgcgatc
     1501 atagcacggt caatagcttg ttgatcacgt acatcgtagc caatgatagc ttcagcaatg
     1561 atgttgttta cgttgtcaac agctttttgt gtaccaagac caccgtaacg agatttgtca
     1621 ccgtcgcgaa gttcaactgc ttcgtgttca ccagtagaag ctcctgatgg aaccatacca
     1681 cgtccgaaag cacctgattc agtgtaaact tctacttcaa gtgttgggtt accgcgtgag
     1741 tctaggactt cgcgagcgta aacatcagta ataattgaca ttttttactc tccttatgag
     1801 ttaaattttt tacacctcta taatacctta aaacccctcc tttttcaaga aaaaacgtta
     1861 tctttgtgca acttttcctt aactttataa agtaatcgct ttcttttgtc tgttttattc
     1921 taacttttat gatatactgt tttcatgaca gatttatcaa aacaattact tgaaaaagct
     1981 catggtgggt taaaaataaa tccggatgag caaagacgct atcttggtac ttttgaggaa
     2041 agagttcttg gatatgtaga tattgacaca gcaaatagcc ctcagttaga aaaaggcttt
     2101 ttatttattt tagaaaacct tcaggaaaaa gcagagccac tatttgtgaa gatttcacca
     2161 actatcgaat ttgataagca agttttctac ttaaaagaag caaaagaaac tgatagtcaa
     2221 gccaccatag tatctgaaga gcatattact tctccttttg gcctggttat tcatagcaat
     2281 gcaccagttc aagtagaaga aaaagacctt cgacttgctt ttccaaaact ttgggaagtt
     2341 aaaaaggaag aaccagccaa aacatcctta tggaagaaat ggtttagcta aatcttgcac
     2401 atatttaata agtgcccaat attggcagcc gtgcgctcca gatagagact ggcatttttc
     2461 aaactatctt ctaaaggttc acttttctcc aaaatagaaa agacagcttg gatattttca
     2521 aatggtaggg gaggtaaatc ttcagcaaga ctaccgcaaa tagcaataac aggaactcca
     2581 acaggggttc tttttgcaac acctataggc gctttcccag caaagctttg actgtcaagt
     2641 cttccttctc caacaacaac caagtcagca tctgaaactt tcttatcaaa gttgattaag
     2701 tccaagcagg tatcaattcc agacacgata cttgcctgag caaaggcaca caaaccacca
     2761 gcaaggcctc cacctgctcc tgctccttta atttctaatg ttgcaggtga gaatttttca
     2821 taaaaatctt ggatcgcctg atctacgact gcaaacatag tcggatgtag acctttttga
     2881 ttgccaaaag tgtaagtcgc accttgataa ccacataagg gactcacgac atctgctaaa
     2941 atatgaattt gaacaccttc aggaatttta tagcgatttt ctgttgaaac agaagctaag
     3001 tttaataagg attgaccgga agcaggcaag acatttccat ccctatcata aaattgataa
     3061 cctaaaccag cagcaatccc cagtcctcca tcattactgg ccgtgccacc aacaccgata
     3121 taaatatctt taatcccttt agaaatgaga tggagaatca actctccaat accacaagtt
     3181 tggatttgaa gtggatttcg tttctctagc ggaatttttc caagaccaac caagtcagct
     3241 acttcaaata gtgccagttc ccctttttga aaatagcgca tggcttcttt ttgtccaaaa
     3301 gggtctgtca cttggatcca tttttctttt aggtcaagag aatgtcggat agcatctaca
     3361 gtaccttctc ccccatcacc aacagggcag aggagacatt ctacatctgc tatcgattgt
     3421 tggaagcctc tttttattgc ttcagctacc tgttgagctg tcaagctttc cttaaacgaa
     3481 tccggtgcaa ttacaatctt catattttcc ctcattctaa acagtcaatc aaaggaagaa
     3541 cttctaaaaa atccctcttg tcaacatgat gtggtatttc ttttttgagc acttctttgg
     3601 cacaaaaggc gattcctaac tccgccgact tcaacattaa tagattattg accccatcac
     3661 cgattgccac cgttctttct ttagaaagtt ttagtttctt tctccatttt tccagagttt
     3721 cttttttgac ctggggactt ataatttgtc caactaattt tcctgttaaa agaccttctt
     3781 tgacttcaag ctggttggca gtgaaatagg caataccaag ggattttgct aatctctcca
     3841 actattggtg taaatccacc agacaccaga ccaactagga tgccattctt ttggagaata
     3901 gagatgaact ctgggacatt tagcgataga tgaattgagt tgaagacgtt atcaaagacc
     3961 aaaataggaa gaccttccaa caaggacact ctttttctta aactgctttc aaagaccaac
     4021 tctcctcgca ttgctcgact tgtaatctgc gaaatttccg cctcatgacc tgcctctctc
     4081 cctaaaagat caatcacttc ttctaggatt aaggttccat ctacatccaa aacacacaag
     4141 ccttttactt gagacatcag ttctcctctc taaacagcct aaaaatcgta tgaagtcatc
     4201 atacgatttt atctattaat taactaaact atggtacaag tcaaggtatg acttgcaggc
     4261 tgtatcccat gagaagtcac tctccatagc ttgtttttgt aggtttctcc aaatgtctgg
     4321 atggtttcta tacaagtcca atgctgtttg gaaagtccaa tttaaccaat aaggagatag
     4381 attgtcaaag ctaaagccag taccgcttcc ttcgattgga ttgaaagcgc gaactgtatc
     4441 tcgcaagcct ccaacttcat ggaccaatgg caaggttcca taacgcatag ccatcatttg
     4501 agacaagcca cacggttcaa aacgacttgg catgaggaag aggtcacaag cagcgtagat
     4561 ttcctgagca agtttgacat caaaagtgat atttgttgat agcttgtctg ggtaaatctg
     4621 agcaaaccat gagaaagctc cttcaaaggc tggatcgcca gttcccaaaa gaacaatctg
     4681 aacatcttct tgcaagatat ggtgaagact ttcgaccacc acatcaaaac ctttttgacg
     4741 tgtcaaacga gaaacaattc ccaccagtgg aacgtctgct ctaacaggca agccaactct
     4801 ttcttgcaat tttgccttat ttttggcttt cccagacaaa tcttcctgat tgaaatgata
     4861 gtctaaaaga gcatccgtct gaggattata aagatcagca tcaatcccat tcacgatacc
     4921 agatacttta ccagactcca ttttaagaat ctgatccaaa ttacatccaa actgactagt
     4981 cataatttca tgagcatagc taggtgaaac ggttgaaaca cggttcgcat agagaatacc
     5041 tgccttcatc cagttcagac agttgttcca tcgaagggtg ccatcagcgt aacgttcaag
     5101 gccaactcca aacaaatcac ccaacattcc ttctgaaaat tgtccttgga attctaaatt
     5161 atgaatggtt aaaactgttt caatgtcctc ataggcttga atccaacggt atttttcctt
     5221 caacaagaaa ggaatcatag ctgtatggta gtcatgaaca tggagaagat caggaataaa
     5281 gtcaatcctt tccatagcct caatggcagc cagttggaaa aaggcaaagc gttctccgtc
     5341 atcaaaatca ccgtaaacat gaccacggaa gaaataatat tgattgtcaa taaagtagaa
     5401 ggttacacca tttaatactg ttttcttaat tccacaatac tgtctgcgcc aaccaacgct
     5461 cacctcaaaa tgaagcacat cttcaatctg atttccaaat ttagcctcta ccatatcata
     5521 gtagggtaaa atcactgcaa cttcgtgccc agcttttacc agtgattttg gaagagcgcc
     5581 aatgacgtct cccaaaccac ctgtttttga aaaaggtgca ccctctgctg ctacaaataa
     5641 aattttcatg aatgaatatc ctctgttact ttagcacctt tcttaaccac aactggatgt
     5701 tctgcagttc ctcgaatcac aacaccaggc tcaacttcaa cccctttgtc caagatagca
     5761 tattcgacct gagccccttt tccaataaca acacgaggga agagcaggct atctttaacc
     5821 aagctatcct tatggacatg aatattacgt gatagaacag aattagctac ttgaccttca
     5881 ataatactac cagaggcaaa ctgagaagtg cttaccttag atgtattagc atagtaagtt
     5941 ggctcttcgt ttttgacctt tgtataaatc ttttggtttg gtgagaaaag agaatagaat
     6001 ttttgtgatt caagcatatc gatattcgct tgataataag atttaacaga gtgaatattg
     6061 gctagatagc ccgtgtactc gtaggcgaaa gctccctctt ttacagccaa atcccgtaaa
     6121 acatagcgca atttctttgg atgttctttt ttagcttctt cttccaagtg ttcaatcaac
     6181 caaggtgtat caacgacaaa gatatctgta gacatattga acatttcagc tgttgacttg
     6241 ctatcaaaga gtttatgaga aagaacatgg tctgtttcat ctacatccaa gattgcattt
     6301 acttctgaaa tatctttctt agctagtttt ttataaacta cagtgatagg ctcttttgtt
     6361 gtactatgta ggtggaaaac ttggttcaaa tcaatgttaa taagaacatc gcagttgagg
     6421 gcaaccgttt ggtttgagcc agaacgtttc aaataagtaa gaagctgttg gtagtattct
     6481 tttccaactg tactactttc tacacgggta ttgtaaattc ctagatagta atgactaaga
     6541 agggttgata agccccactc gcgtcctgaa cgaatatggt caaatactga gctgatatta
     6601 tcctgctgga aaataccaaa gacactacga acacctgcat tagcaaggct tgaaagtggg
     6661 aagtcaatca aacgatattt cccaccaaat ggcaaacttg ctactggacg gtggtccgtc
     6721 aatgtcgaca tattgtgaaa accaactgta tttcctaaaa tggcagaata tttatcaatc
     6781 ttcatctgtt gctaccccca ctacttcatt atatcctaca acttgtactt catctgttcc
     6841 atcaatttcg acaccgtcag aaataatcgc accttcacca ataatggcac gtttaatctt
     6901 agctccttga ccaatgatag ctccactcat gataactgaa tcaaggactt ccgctccttc
     6961 gcgaacttgc gcgcctgttg aaaggataga atgtttaaca gctccatcaa cgaaacatcc
     7021 gtctacaact aatgagtctt ccacatgagc atttgccccg aggaagtttg gtggtgaaat
     7081 caagtttctt gagtaaatct tccattgacg gttacgacta tccaaggcat tttctggaga
     7141 aatatactcc atgttcgctt cccaaagtga ctcaatagta ccaacatctt tccaataacc
     7201 actaaattcg taagcataaa cactttcacc tgactcaagg taatttggaa tgacattttt
     7261 accaaagtct gacatgccaa ccttgctctt ttcagcagcg actaacatat tacgaaggcg
     7321 ttgccaatca aaaatgtaga ttcccataga agcttttgta gatttaggtt gagctggttt
     7381 ttcttcaaat tcaacaatac gattgttagc atctgtgttc atgataccaa aacggcttgc
     7441 ttctttaaga gggacgtcta aaactgctac tgtcaagctg gcattattat ccttatgaga
     7501 ctggagcata tcatcatagt ccattttgta gatgtggtcc ccagacaaaa tcaagacata
     7561 ctcaggattg acactgtcga tatagtcgat attttggtaa atagcgtgac tagttccctc
     7621 aaaccaacga tttccttcac ttgcagaata aggttgaaga atagagacgc ctgaattaat
     7681 accgtctagt ccccagcttg aaccattccc aatatggttg ttgagagcaa gtggttgata
     7741 ctgtgtaacg accccaacat tatgaatccc tgagttggca cagtttgata gggcaaagtc
     7801 aatgatacgg tagcgcccac caaattgcac agctggtttt gcgatgcttt gagtgagttt
     7861 accgagacga gttccttgcc caccagcaag aatcaaagct aacattttat ttttcatttt
     7921 ctactccttt ttggttttta tttgtgacgg ttttagtaga tttcaagcga cgtttgattt
     7981 tccatacact tgctcccata gccggtagag taaaggttaa ggtctgctca taatctttcc
     8041 ataggccttc ttgcgtttga acagtttgat tatgttcttt ccaaacgcct ccccactctt
     8101 ccaactcagt attccatact tcttcgtaaa ttcctgcaac gggtagtccg attgtaaaat
     8161 ctttccgctc aacaggtacc atgttaaaga tacagactaa catttctccc tttttaccct
     8221 tacgaataaa ggaaagaaca ctctggtctc gattatccgc atcaatgatt tcaataccat
     8281 catagctggt atcgatttcc cacagacagc gatgatcttt gtaaaactgg tttagctgag
     8341 aagtgaaata cttcatctta gcattcattg ggtcttctag gttagaccat tccaactgtt
     8401 cttcagattt ccattctagg aattgaccgt attcgctacc catgaagagc aatttcttac
     8461 cagggtgaca aatttggtac gtatagagat tgcgcaagcc tgcgaattga ttgtaacgat
     8521 ctccccacat cttatgcatc atactcttct tgccatgaac cacttcatcg tgcgagaatg
     8581 gcaagagata attctccttg aaaacataca taaagctgaa agtcaccagg ttaaagtcat
     8641 atttacgata aatcggatct tcttcgtaga aacggaggat atcattcatc cagcccatgt
     8701 tccatttgta gtcaaatcct agaccaccaa tctctttcat tcccgtaatc ttggtcgcag
     8761 acgaactttc ttctgcaatc atcatcacat ctggatattc taacttaata acttcattca
     8821 agcgttgaag aaaataataa ccttcatagt taagatttcc gccatcttta ttaggtgtcc
     8881 atggagcatt atcatagtcc aaatagagca tgttgctaac agcatccaca cgaataccat
     8941 ccaaatgata gacatcaatc caatgcttaa tgcaagaaat taagaaggac tggacttcat
     9001 tttttccaag gtcaaaatta agggcacccc aaccatggtt atgagcctta ttatggtctt
     9061 ggtattcaaa agtcggtgtc ccatcataat aggctaaggc atcatcgttg atggtaaagt
     9121 gacctggtac ccagtccaca ataaccccaa tattatgggt atgacactcc tcgacaaaat
     9181 cttgaaactc ctctggtctg ccataagcat gctctaaagc gaagtaaccc ataagctgat
     9241 acccccaact caagcccaaa ggatgggaca tcaagggcat aaactcaata tgagtatagt
     9301 tcatttcaac gagataagga atgagttcat ccttgagctg ggcaaaacta taaggactgc
     9361 catcaggatt tctcttccaa gagccagcat gaacctcgta aatattgaca ggacgttcaa
     9421 caaagcccca acgttttctt cgtgccagcc aaagtccatc cctccatttc ttatcaggaa
     9481 gctctgttac gattgcccct gttcctggac gagcctcata cctgacagca aaagggtcaa
     9541 tcttcatcag ttgatgacca ttttgacgtg tgacatgata tttgtaaata tgcccttctt
     9601 gagccatatt ggtaaagact tcccagaccc caaagtcatt tcttaccatt ggaatctgat
     9661 tttcaatcca gttggtaaaa tcaccaacca agtgaacagc ctgagcatta ggtgcccaaa
     9721 cacggaaggt atagccatgc tctccattta gttcttccct atgtgctcct agataatgtt
     9781 ggagataaaa attttcaccc gtcataaagg tttttaatgc ttctctatta tccatatact
     9841 ccccttctcc tgtaagcgtt ttctatgttt ttattatact acctttttag agaagattca
     9901 agtaaattac tatacttctt taattatttt gaaaatctac aacaagttca cttactcgtt
     9961 caattgtaaa tcaatatttt ttcaaaaaat tgcgaaaacg cctttctttt tctactatag
    10021 tgaaatgaaa taaaacatg
//
LOCUS       DBERDS010000062         9732 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.062, whole genome shotgun sequence.
ACCESSION   DBERDS010000062 DBERDS010000000
VERSION     DBERDS010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.062"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            88..669
                     /locus_tag="ACL73E_001839"
                     /pseudo
     CDS             88..669
                     /locus_tag="ACL73E_001839"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            666..1856
                     /locus_tag="ACL73E_001840"
     CDS             666..1856
                     /locus_tag="ACL73E_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGS0801765.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(2366..3357)
                     /locus_tag="ACL73E_001841"
                     /pseudo
     CDS             complement(2366..3357)
                     /locus_tag="ACL73E_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            3517..5271
                     /locus_tag="ACL73E_001842"
     CDS             3517..5271
                     /locus_tag="ACL73E_001842"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801766.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            5255..6976
                     /locus_tag="ACL73E_001843"
     CDS             5255..6976
                     /locus_tag="ACL73E_001843"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801767.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            6987..7571
                     /locus_tag="ACL73E_001844"
     CDS             6987..7571
                     /locus_tag="ACL73E_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGS0801768.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            7571..8266
                     /locus_tag="ACL73E_001845"
     CDS             7571..8266
                     /locus_tag="ACL73E_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGS0801769.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            8254..9618
                     /locus_tag="ACL73E_001846"
     CDS             8254..9618
                     /locus_tag="ACL73E_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801770.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKVEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         3606 a         1295 c         1661 g         3170 t
ORIGIN      
        1 attttattta taacaagagg atagaaatga ccgaattaga aagaaaaaat cgaaaaatta
       61 gctaagaaat attctgataa cttaaacatc aaagttcaag agagagttcg tgaaatggca
      121 aatgataata agagccatta tttgatatac agagttttag gtatttcatt tgaagaagga
      181 gaaaatatcg atttgtatca aaataaaggt cgttttttat acaaatatgc tggttcattt
      241 ttagaagaag ctgcagtact atcctttaac gaaaaatttg gtacagaaaa tacttaaaaa
      301 gttaacattc ctaattctga aagtacaaaa cctaagactt ttgaaattga ttgtttagtc
      361 ggagaaaaac acgcatacga aataaaatgg tgggatgcaa ctacagatgg agaccatata
      421 actaaagaac acactagaat aaaagttatt cataacaaag gatatatacc aattcggtta
      481 atgttctact atccaaatag aactcaagct ataaaaattc agcaaacttt agaaacattg
      541 tataacggta ttggagggaa atattatgga gattctgcct gggaacattt aagagcagtg
      601 accggtattg atttacttag tattctaaca gatattgcaa ataaaaaaac aggggtaaaa
      661 tcaaaatgac agtattaaaa ggagataact tagaaatatt aaaaactatt gaatcctcaa
      721 gtattgattt aatctatatg gaccctcctt tctttacaca gaaaacccaa aaattatcta
      781 ataacaaaaa tattatgtat tcattcgaag atacgtggac ttcgattgag gattacaaag
      841 aatttttgtc tgtaagatta gaagaatgca aaagagtgct aaaaaatagt ggcagtattt
      901 tcgttcattg tgataaaatt gcaaatcatc atattagatt aattttagat aatatctttg
      961 gagcagatat gtttcaaagc gaaattatat ggaactataa gcggtggtct aattcaaaaa
     1021 agggattatt gaacaatcat caaaacattt acttttattc aaagtcaaaa gattttaaat
     1081 ttaatacaat ttttacagag tattcttcta ctacaaatat cgaccaaata ctagtggaac
     1141 gaaaacgaga tggaaactct aaaactatat ataaagttga taataatggt aactatattc
     1201 tagcaaaaga gaaaaatgga gttccccttt cagatgtttg gaatatacca tttcttaatc
     1261 caaaagctaa agaaagagta ggttatccta cacaaaaacc tattctgtta ttagaacaaa
     1321 ttataaagat tgctactgat aaaaatgata tagttttaga cccgttctgt ggaagtggaa
     1381 ctactttagt agcctccaag attttgaata gaaattatat ggggattgat ttatctgagg
     1441 aagctatcaa tataactcag caacgtctgg aaaatgttat aaaaacaagt tcaaatttat
     1501 tgaataaagg aatcgaagca tatagaacca aaactgagga agaggaaaac attcttaaat
     1561 tattacaggc aaaaattgtt caaagaaata aaggaattga tggtttttta cctaaacatt
     1621 ttcaaaaaaa accgatacct ataaaaattc aaaaaaataa tgaatgtctg aatgagagta
     1681 tctctttatt acagaatgct ataaactcca aaaaacttga ttttggagta gttataaaaa
     1741 ctcattcaga taatttatta tttgattttg atacgattcc tgaaaatata atagtagttg
     1801 accattttga acttacaatc gaaaaatggt taagtaaaag tcaacagtta ctatagtttg
     1861 caaattattt acagaaagaa caaaaaatgc tctgaaacac tgatttcaaa gcattttttg
     1921 ttagtttaaa attactccca ttcttctttt ccaaacgtac aatatatcca aaaccattca
     1981 aaatactaga ttctattttt tataatatca ctaaatccac ctaattatag gacgttttca
     2041 gatttttagt cccagtccca gtaccggaga aatattgttt taatataata tctctttttg
     2101 tcttctaagc tcttaaaagc aaaagaacaa gtaaagagtc aagacaagga taaaaagtcc
     2161 atattagggc aaataaaaag ctttaagaca gatgacaaat ctaagtcaaa taagaaagac
     2221 catagcaaag gtgcagagag ataaatattg gcggtcttcg gactgccttt atttttttat
     2281 ccatttttca aatcaaattt attcagacta tatatgcaca tatacactta aattcatata
     2341 aaaacatggc ttgtaaaaaa ttactttaat cacaataatc gcatttaaaa ttgtgatgtt
     2401 tgcaagctaa attacggact tcacttggaa gttttccctt gtatctttta taatagatag
     2461 aaaatttgct ggcagatgat atccaacaga ttctgctatc tcttttatag gtagttcagt
     2521 gtttaaaaga agagtttcag ctacattcat tctttttctt tgagtgtact ctgtaatgct
     2581 ttgacaatat ttttccttaa ataaattttt taatttagta ccactcattt tagatatttt
     2641 ttcaagcgtg ccttgattta cattcgttgc aaaatgatca tctaagaatc ttgctacatc
     2701 ttcaagtgct ttatcatcat caatttcaat tttatatttt tttctattta agtatgtgtc
     2761 aattactata cttatccatt catttgcctt tgctttaaag aaaaaatcag cggcaggagc
     2821 gtccatctta caatttaata tttccattgc cactctttct aaggcctttg taagtattat
     2881 ttgattcggt tgaagcaagg ttgaataaaa agattctgga ttaatgttaa tagatgctaa
     2941 atgtttttct attagctctt ttttaaaacc aatggaaaca gcaagataac aacaattctc
     3001 gtgtaataaa aaaacaaaat catcttttat attatcaaaa tcaaaagtac atagagagtt
     3061 tgcggtaata gtttgatacg gattaaactt ttctccgttt gcactgacaa tgtaacttga
     3121 ataaattgaa acatagtctg acatactata agtgctattt tgaactactt cctctttgat
     3181 ataaaaatca tgtatatcga taatgaagct gcctccttca taaaaccaat atagtccttc
     3241 tgcataagtt gaattctctt ttttccaaca aaatgtatga cctgcacttg aatacttctc
     3301 attgttttta cattcatcta ctttcatata atcttttaca aaatcataat atgacataac
     3361 acactatccc ttttagacaa tattccaatt agccttatta attcaaaact attgtattag
     3421 taattataac agatgtataa tagaaaagca atgatagata ttatcaatta agcgaattta
     3481 tatctaaaag ggatattaaa gaaaggagat atgcttatga agatttacaa aaaactattt
     3541 gcttatgtcc aagataagaa atatcttggg gttttggcca taattttttc tgctatatct
     3601 gctctactta cagtatatgg atattattta atctacaaat ttctagataa gttaataatt
     3661 aattcaaact tatccggtgc agagagtata gcattaaaat ctgttattac actaacaagt
     3721 ggagcgatat tttattttgt ctcaggaatg ttttcacata tcttgggatt taggcttgaa
     3781 acaaatttaa gaaaaagggg aatcgatggt ctggaaaaag caagttttag gttctttgac
     3841 ttaaatccat ctggtcaaat aagaaagatc atagatgata atgcagcaca aactcatcag
     3901 gtggtagcac acatgattcc cgatagttct caggcaataa tcacacccgt acttgtactt
     3961 gcacttggct ttatagtaag tataagggtt ggcataattt tgcttgctct tactataatt
     4021 ggtggcttaa ttttaggggc aatgatgggc gagcaagaat ttatgaagat ataccaagaa
     4081 tccctatcta aactaagtgc tgaaactgtt gagtacgtga gaggaatgca agttgtaaaa
     4141 atatttaaag caaatgtaga gtcttttaaa agcttttata aggcgataaa agattactca
     4201 aagtatgctt atgattattc cctatcttgt aaaaggcctt atgttttgta tcaatggtta
     4261 ttttttggac tgattgcaat tttaattatt cctatagttt attttatgac tagcttagct
     4321 agcgcaaagg tgattttact tgagcttatc atgattttat ttttatcagg agttctcttt
     4381 gtttcattca tgagaatgat gtggtactcc atgtatattt ctcaaggaaa ttatgcagta
     4441 gatactttag aggcgcttta cgaagatatg caaaaagaca aattagtgca tggtaatgtc
     4501 aataatttta aaaactataa tatagaattt gagaatgtta gctttgctta taatgataaa
     4561 gctgtcattg aaaatttatc ctttaattta gaagaaggaa agtcctacgc acttgtcggt
     4621 tcatctggat caggcaaatc aacagtagca aaacttatat caggttttta caatgttaat
     4681 aaaggaagca taaagatagg cgggatagca ataagtgaat attctgacga agccttaatt
     4741 aaagccattt cctttgtttt tcaagattca aaattattca agaagagcat ttatgataat
     4801 gtagctttag ctaataaaga tgcgacgaaa gatgacgtta tgagagcctt aaaattagca
     4861 ggatgcgatt taatattaga caaattccca gaaagagaaa atacaatcat aggctcaaaa
     4921 ggtgtttatt tatccggtgg agaaaaacaa agaattgcaa ttgctagagc aattttaaag
     4981 gattccaaaa ttattattat ggatgaagca tcagcatcta ttgacccaga taacgagttt
     5041 gaattgcaaa aagcttttaa aaatcttatg aaggataaaa cagttatcat gattgcacac
     5101 aggctatcta caattaaaga ccttgatgaa attattgtca tggatagtgg aaaaattata
     5161 gaaagagggt ctgacaaaga attaatgtca aaagatacaa ggtataagag cctgcaagag
     5221 atgtttaaca gtgcgaatga atggagggtt tcaaatgaaa gagttttata aaaaaagatt
     5281 tgctcttaca gatggaggag caagaaattt aagtaaagca acactggctt catttttcgt
     5341 ttattgtata aacatgcttc ctgccatatt acttatgatt tttgctcagg aagttttgga
     5401 aaatatgggc aaaagcaatg gcttttatat agtattctca gttttgactt tgatagcaat
     5461 gtatattttg ctttctatcg aatacgataa attatataac acaacctatc aagaaagtgc
     5521 agatttaaga ataaggacag cggagaattt atcaaaatta cctctatctt acttttctaa
     5581 acatgacatt tccgacattt cacaaacaat catggctgat attgaaggca tagagcatgc
     5641 aatgagccac tcaataccaa aggtgggcgg catggtactg tttttcccat taatatctgt
     5701 aatgatgcta gcgggcaatg tcaagatggg tttagctgta attattccat ctattttaag
     5761 ctttatattt atacctttat ctaaaaaata tcaggttaat ggacagaata gatattatga
     5821 tgtcttaaga aaaaactcag aaagctttca agaaaatatc gaaatgcaaa tggagattaa
     5881 agcatataat ttatcgaagg atattaaaga tgacttatat aaaaaaatgg aagatagtga
     5941 gagagtacac ttaaaggcgg aagtaactac aattttaact ttgtctatat cttcaatatt
     6001 tagctttata tctcttgctg ttgtgatatt tgtcggcgta aatctaatta ttaataaaga
     6061 gataaattct ctctacctta taggatattt actagctgct atgaagataa aagactcttt
     6121 agatgcatct aaagagggct tgatggaaat attttattta tcgcccaaaa tagaaagatt
     6181 aaaagaaatt caaaatcaag atctacaaga aggcgatgac tatagcttaa aaaaatttga
     6241 tattgatcta aaagatgttg agtttgccta caataaagac gcaaaagttt taaatggtgt
     6301 aagttttaaa gctaagcagg gagaggtcac tgctttggta ggtgcaagtg gctgcggtaa
     6361 aacaactatc ttgaaactta tatcaagact ttatgattat gacaagggac aaatcttaat
     6421 cgatggcaaa gatataaaag aaatatcaac agaatctctt tttgataagg tctctatagt
     6481 tttccaagat gtggttctct ttaatcaaag cgttatggaa aatattagaa tcggaaagca
     6541 agatgcaagt gacgaagagg ttaaaagagc agcaaaactt gcaaattgca cagattttat
     6601 agaaaaaatg gataaaggtt tcgatacagt tattggtgag aacggagctg agctatcagg
     6661 aggagaaaga caaagattat caatagccag agccttctta aaagatgcgc cgatattgat
     6721 cttagatgag ataacagcaa gccttgatgt taacaacgag aaaaagattc aagagtcttt
     6781 aaataattta gttaaagata aaactgttgt aatcatttca catagaatga aatccataga
     6841 aaatgcagac aagatagtag ttcttcaaaa cggaagagta gaaagcgaag gtaagcatga
     6901 agagctttta caaaaatcaa aaatttacaa aaatttaata gaaaagacaa aaatggcaga
     6961 agaatttatt tattaggagg actacaatgg ataataaaaa attaaaagta aaagatttag
     7021 taagcatcgg tgtttttggc gtaatttatt ttgccttcat gtttggagtt ggtatgatgg
     7081 gcttgattcc aatattgttc ttaatatacc cgacagtatt agccatagtt gcaggaactg
     7141 ttgttatgtt atttatggct aaggttcaaa agccatgggc actatttata tttggtatga
     7201 tatcaccact tgtgatgttt gcagctggtc atacctacgt agttgtggtt ttatcactta
     7261 tagtaatgat aatagcagaa ttaattagaa agattggtaa ttataattca tttaaataca
     7321 atatgctttc ttatgcaatc ttcagcacat ggatatgtag ctctttaatg caaatgcttt
     7381 tagcaaaaga aaaatatatg gagtggtctt tgatgacgat gggaaaagat tatgttgatg
     7441 tattagaaaa gttaataact tatcctcaca tggctttagt agccttaggt gctttcttag
     7501 gaggaattct tggagcatat ataggcaagg ctctattgaa aaaacacttt gaaaaagcag
     7561 gcattgtata atgcctactt tttcttcaaa tgctcccttt aatcccaatc cgatctctaa
     7621 gatattagtc gtatttatca caggcttaac tgttatgcat agcataaaca tccgttttga
     7681 gctggcaatt gtttgtctta ttggtatttt gctttatttg aatggataca aaaaaacact
     7741 tttcaaatgg attatattgt gtgggatact ttactccttg cctaatttta tggtgttatc
     7801 tgaattaaac cctatagtta agatgttttt gagtatacct attgttatta gaatgtttat
     7861 tttaccattt atggcagcaa gctttatgat aaagacctcg gatgtaggcg caataatttc
     7921 atcgatggat aagcttaaga tttcaaagaa tgtatccata cctattgcgg ttatgtttag
     7981 attcttccca tcttttaagg aggagaagaa aaacatcaaa atggctatga gagtaagagg
     8041 gataaatttt aaaaacccag tcaaatatct tgaatatgtt tctgtgccac tactcattat
     8101 atcatctaat atatcagatg acattgcaaa agcggcagaa acaaaggcaa tagaaaatcc
     8161 aattgccaag accagataca ttcgcgtaaa gatacagcta attgattttg tttatgtttt
     8221 agcggttgtt ggacttattg tgggaggctt aatatggttg aaataaaaaa tttaagtctt
     8281 gattatggtg aagagcatat attagatgat atatcactat ccatagccga gggagagtgc
     8341 gtgctattta caggaaaaag tggaaatggt aagtcatctt taataaattc aatcaatgga
     8401 ctagctgtaa ggtatgataa cgcaaagaca aaggtcgaaa taattattga tggtaagaat
     8461 ataaaaaatt tggaacttta tcaaatctca atgcttgttt caactgtttt tcaaaatcct
     8521 aagacatatt tttttaatgt caatacgaca ttagaattat tattttattt ggaaaatatc
     8581 ggtcttgcaa gagaagagat ggacaggcgt ttgaaggata tgcttgagat attcccgata
     8641 aaaaatcttt tgaacagaaa tatatttaat ctatccggcg gtgaaaaaca aattctttgc
     8701 attgcagctt cttatatagc aggtacaaag attatagtta tggatgagcc ttcatcgaat
     8761 ttagatatta aaagcataag tgttttggca aagatgctaa agatattaaa agagaaaggc
     8821 ataagcataa ttgttgcaga gcatagaatt tattatttga tggacatagt tgaccgtgta
     8881 tttttaatag ataaaggaaa gcttaaaaaa acttatacta gaagtgaatt tttaaagcta
     8941 gataaaaatg aattaaatgc tttaagttta agagataaag aattaagtaa attaaaagtt
     9001 ccttatttaa aagaaggtgg agagtatcag ataaaaaatc ttagctacaa atttactgat
     9061 gatgagtgtt taagcttaaa agatatttcg ttcaagcttg ggaaaattta tggcataata
     9121 ggatccaacg gacgaggaaa atcaacgctt ttaagatgtt taataggtct tgagaaaaaa
     9181 tcaaaagaag aaatttattt taagggagag aagctatcta aaaaagaaag actcaaaaac
     9241 tcttcacttg ttatgcaaga tgtaaatcat caattattca cagatgaagt attcaacgag
     9301 cttagattag gagtaaagaa ttttgatgaa gaaaaggcga aaatcatttt aaaagattta
     9361 ggcctggacg aatttattga aaggcatccg atgagtttat caggagggca aaagcaaagg
     9421 cttgcaatag catctgttat gtgcaagaat tctccatttg tcttttttga cgaaccttca
     9481 agtggtatgg attattccaa tatgataaaa atatctgaac tgattaataa gtataaaacc
     9541 atggataaaa taatttttat tgtttcccat gatatagaat ttttaaatga agtggcagat
     9601 gaaatttttg aattgtaaaa tagagtctgt taaacatgtc tatagaacta gtaaattgtc
     9661 taaaaattta aaagatacta acacatattg atatttatta gaaaattaac ttcaggattt
     9721 ttacagtatt ta
//
LOCUS       DBERDS010000063         9028 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.063, whole genome shotgun sequence.
ACCESSION   DBERDS010000063 DBERDS010000000
VERSION     DBERDS010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9028
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.063"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            31..1254
                     /locus_tag="ACL73E_001847"
     CDS             31..1254
                     /locus_tag="ACL73E_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGS0801771.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            2686..2970
                     /locus_tag="ACL73E_001848"
     CDS             2686..2970
                     /locus_tag="ACL73E_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801772.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            3297..3515
                     /locus_tag="ACL73E_001849"
     CDS             3297..3515
                     /locus_tag="ACL73E_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801773.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(3882..6206)
                     /gene="pflB"
                     /locus_tag="ACL73E_001850"
     CDS             complement(3882..6206)
                     /gene="pflB"
                     /locus_tag="ACL73E_001850"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGS0801774.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            6554..7615
                     /gene="dinB"
                     /locus_tag="ACL73E_001851"
     CDS             6554..7615
                     /gene="dinB"
                     /locus_tag="ACL73E_001851"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGS0801775.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(7762..8607)
                     /locus_tag="ACL73E_001852"
     CDS             complement(7762..8607)
                     /locus_tag="ACL73E_001852"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGS0801776.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(8638..8775)
                     /locus_tag="ACL73E_001853"
     CDS             complement(8638..8775)
                     /locus_tag="ACL73E_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801777.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            8862..>9028
                     /locus_tag="ACL73E_001854"
     CDS             8862..>9028
                     /locus_tag="ACL73E_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0801778.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIAL"
BASE COUNT         2996 a         1709 c         1611 g         2712 t
ORIGIN      
        1 taatataaaa taaaccaaag gaggaaacaa atgattacaa aacaatcagc ctttttacaa
       61 aatagagcca ctatactgga gtttctatat cgaaatccag caacatcccg tacagatatt
      121 gttaatgaaa caggacttac tccagcaaca acgactaaca tcataaaaga gctaagcgaa
      181 cagtccctca tatacgaaac tggtgatgaa tttagcgagt tttccggatc tggaagacgt
      241 agaaaaacta tttctatcac agataatatt ccgtatgttg ttggaggtat tgaaataaac
      301 gtcctaggta tctttctcag tctatgtgac ttacaaggga aaactctttt cgagacagaa
      361 attttgaatg aagattatcc tatttcagaa atcaattcca ccattaccaa tatgataaaa
      421 acagctatag agtacgtccc tttggaaaca aaattacttg gatttggctt atcaatacct
      481 ggacattata acaaagactc cggaagtatc attacaaaca accccatatg ggaatctttt
      541 aatttattaa atgtaattaa aagattcaat tttcctttta ttgtaaaaaa taatatcgat
      601 tgtatggcta taggacaata cctttttaat ccacacaata cccccgataa ctttattttc
      661 ctacacgctg gattaggtat ttacacttcc tttttcacaa aagaaaaaat aggagcctct
      721 aaaaatcctt atatcggaga aattggacac accattgtcg aattgaatgg gcaatattgt
      781 gaatgcggaa aaaaaggttg tttacaaaca tatatttcgg atgcttggtt aatcaaacac
      841 gcccaattat tatttaaaaa ttcccaacta actgtactaa aaagccttgt aaagactgaa
      901 aaagacattc atttagacac ccttttaacg gcttataatt taggcgactc cgctttacgt
      961 caacaaattg ataaaggagt caatttatta gccacttcta ttgcaaatct cctcctcatc
     1021 aatcctgctg ataaaatcta tatcaacagt caattgctta attatcaacc tttcactcat
     1081 gaagtcaggg ataaaatcca agaccagctc cacttcgttc cctttactcg taatatagaa
     1141 attgaaattt taccttacaa caaacatcgt ggaagtatag gagcttgtgc attagctatc
     1201 gtcgcttttt tcatagaaca tagcaatgta ttacaagata ttatttcacc ttaatatatt
     1261 agaaatctat agacctgttt aaatcaacta taacctgtag tagatatctc gtatttagac
     1321 aatatgaaaa caagacgact tccatatagg aaaccgcctt ctctctatgt tgagtgattt
     1381 atattaaaat aacttttctt ctagctgcat tttattatta taaaaacatt catcataacc
     1441 ctgaacttaa ataacgattt ttattcaaga tacatactcc tagaataaac tttatatgaa
     1501 attctcattt ttgtttttac aattctcctt agttaaatct tgtttaatat atgttttaca
     1561 tatagtattt agcgccacat agtactgaac tctctccaaa aacggttatt cctctttgaa
     1621 tagggcgtta tcacaagaaa agcatctcca cgtttcaact tcatatggct caaaaacaat
     1681 caattgatgc taaaacctgt acctagatgt ttcggttcat aaaaccatga aactgtaaaa
     1741 gtggatgaaa ttgatagcga tagtcaaatc aagaggcatc ataactctaa aaagtcacaa
     1801 tatataagtt catcctcgga aaaatatcat tctaattgtt gaaatgccta catgaaaaga
     1861 aacgtcaaat gctcatgaaa caacgaatac aggtatcaaa actatgacaa aacaagtccc
     1921 taaatttact aaagacactg ctcaacttta cacctgtaaa tggttgttgt ataataaagt
     1981 tacaaagatg tacgaccaca ctgttgtaaa tcatagtgtt cgcgaatata ttactgatag
     2041 catttctaca aatacaattg aagagactgg atagacttta aacgaaatat gtcagtgttt
     2101 tggcattcct agccttcata tcatttaaag aattctatag acaaaatttt tcccaataca
     2161 gacactcgta acaactgctt catttttcta ccaacatatt taggaacagg ataagataga
     2221 agaagattaa tccatagctc agttctatac caatctaaga caaataagct aaaaaaacga
     2281 ttgataataa gcaaatagat tccaaatttt ctctatctgc tcattttaat aaacaatact
     2341 agtgtaacta tccttccagt cagaaacttg tcaaatcaca ccgaaaactc ttctaaaatt
     2401 tatctcgtta ggcaatcaag caaaaactcg acgatagtac aaacattatc atacagaatt
     2461 gactgcctaa attatatact ttagtaaggt tttcggataa gaaaaaaggt tcattttaca
     2521 tttctaaaca ttcttttcta agatgaaaaa cagaattttt cgattgtgat ttaaagcaac
     2581 aagaagattt tcagtatcat cctatagata cgagctaatt aagaaaaact acatttttga
     2641 atataaacta caataatata aactaaattt tataggagga agacaatgga ttggtacgat
     2701 tatatgatac aggcatccaa acaatcacaa ttcaacgcaa gccattggtt tcgctatttg
     2761 cgaaaagtta tttttgaaga ctattcttat ttaacaaacc aagatgtaga aaagttgcta
     2821 gactccaaag aactaacccg ttttcaaaaa attagcttga agtatgcctt tcaagagcat
     2881 actccaactc ataaatatgt gatttcatta aataaacctg ctaagttaac caatgttcaa
     2941 aaattgatgg agaaatacaa acatggataa aatgaaaccg gtcttccaag ccctaaataa
     3001 gaaattaatt caggaaaatc tgactttaac aattatggtt atgtcttaga atatcatggt
     3061 ttacgtgcca cacaagatgt tgatgctttt tatgaccaaa atcagaaaat caatgaaatt
     3121 attgctcgtg taggaaaaca gtttaatctt aacatccacg aagagttatg gctcaacaat
     3181 catgttgcaa agcaaatatg aacaaacaac ctcccttaag tttatgcgaa tccttgtact
     3241 catttgagaa tctgaccgtt ttagtagtcc ctattgagta tgtgttagga atgaagatga
     3301 tgagtatcag agagcaggat ttgcaagata ttggtgcaat tattaaatac aaaaactttc
     3361 attcaccatt cgataccttt aaatatttaa aagacatggg atttgatact attgacctct
     3421 ctgttctatt agaaggtttt agttatgctt atggtatgga ttggttagaa aaatttttta
     3481 aagaaaatca agataaactt cgcgaatttt attaacagta tcaaacaaga tgattgtcaa
     3541 ttagccagtc atcttatttt tatgatgaaa tgaaataaaa tcggaacaaa tcacttagag
     3601 aattccagtc aatttctagc actgtttgag ccgtttcagc ggactatagt aaaatgaaat
     3661 aagaatagga caaatcgatc aggacagtca aatcgatttc taagaatgtt ttagaagtaa
     3721 aggtgtacta ttctagtttc aatctattat atttcagatt cggtccacta ttccttccca
     3781 aaaacattgc atattgcgcc gaaggaattg ctcatactat cccaagcaca aaaccctcag
     3841 tcgtttgacc gagggttcct ttttattatt caagaacttg attagctcaa tgcatccaag
     3901 gcgtcatcca ttgaaagaac ttcgtggaag acacgttgtg tcaattcagt tttttgttct
     3961 ggagtgaggt atttagtgtt tacacagtat ccagagatac gtacgataac gtcttcgcct
     4021 gacatgattt tttcgtaaac atcgttcaag tccataacgt tcaagttaac gtgttgtcca
     4081 ccgttttcga agtaaccatc aaggattgtt accaagttat caacttgttc atcacgagtc
     4141 ttaccaagag cgcgaggtga tacttgtgta gtcaatgaga taccgtcagc tgcataacta
     4201 aagtcaaggc tagaaagtga gttcaagttt tgcaaccaac cacctttagc tttgttagat
     4261 gggttagcac ctggtgagaa gaattcaagt ttagacaagt tcacagaacc atcttcgttg
     4321 aggtatacac ctttgtgaac tggtgagtta ccagtttgtt tagagtaagc aacgttagat
     4381 gtgattgtca aaagtgatac tgtagcttct gcgtctttgt atagtttgtg gctacgtaga
     4441 cgagttgtgt aagcttcgat caaccattct gccaattcgt ttgaacgtgg gtcatcttca
     4501 ccccagcgtg ggtagtcacc gattgtttcg taatcgtaga tgtagccatc ttcgtcacgg
     4561 attggtttaa ctgtagcgta tttgatagct gacaatgtat caacagtgtt agcaaatcca
     4621 cagataccga atcccatgtt ggcacgttgt ttagttggca agaaggccat ttgaacagct
     4681 tcgtagttgt acctatcagt catgtagtgg atgatgttca aggcatctac gtaagtgtca
     4741 gtcaaccagt caagagattt ttcaaagttc gctttaactg attcaaattc aagaacttcg
     4801 tcacggattg gttcgatatc aaatactttg tagtctttgt gaacatcgtc gtaaccacca
     4861 ttcaaaccag taagaagggc tttaagaacg tttacacgag caccgaagta ctggatgttg
     4921 tggcgttgtt cttcattttc tggatcaagt ggagacacac agcatgagat acagctcatt
     4981 tcaccatatc cgtctttagc cattgttgtt acaccttcgt attggataga agagtgtttg
     5041 tggctcatgt gcatacagta gcgacggaag ttgtatggca atttgtcagt ccaaagaact
     5101 gtcaagtttg gttctggtga gttaccgatg ttgtcaagag tgttcaagaa acggtagtcc
     5161 atcttagtaa cacggtgacg accgtcgtta cccataccag ccatagaagt tgtgataaag
     5221 gttgggtcac ctgagtacaa ttggtcataa gcttttgtac gagcaaattt aactgtacga
     5281 agtttcataa cgaaatcatc aacgaattct tggatttctg attcagtaaa tgtaccacga
     5341 gcaaggtcac gttctgcaaa gatgtccaat acgattggta cacgacctag agatgtagca
     5401 gcaccgttaa tcacacggca gacagccatg aaagcaatgt taacccattg gattgcttct
     5461 ttcacgttca tcgctggttt gcgaacatca accccgtaaa ggtcacccag gcgaacaact
     5521 tgttgcaatg cttggtattg aaggtttact tcttcacgaa gacggattgt ttcttcatcg
     5581 atttctttga ttgcattcca gtcatttact ttttcttgca tcaagtagtc tgcaccgtaa
     5641 agagcaagac gtgcgtaaac accgatgata cgtccgcgtg agtatgcatc tggaagacca
     5701 gttacagtgt gtgcgtgacg agcgcgacga atatttgaag tgtaggcacg gaaaataccg
     5761 tcgttaactg ttgttacata tttagtgaag atttcgtgaa cagctgggtc tggttcgtat
     5821 ccattttctt tcaaagtagt ttcagccata cggataccac cttttggcat gaagttcaat
     5881 ttgaagagtt catcgttttg gataccgaag ataacttcat tttctttgtc gataaatcca
     5941 gcagggatat cagcgataga tgttggacga gtgtccattg ggaaacgagt ttcttcgtag
     6001 tgtgctttag tttcttctac aattttcttg atgtgaagtg aacgctctgt tggtcctgca
     6061 aggaagcttt cgtctccatc ataaggtgtg tagttagctt gtacaaatcg tgatacactt
     6121 gctttttctt tccaatctac gcctttgaag ccttcccaag ctttgtcaaa aatatcttgt
     6181 gcttcaacaa ctgtcttaac aaccatatta atgtcctctt ttttctagta acagtcatct
     6241 gttacattca taagacaagt ataccatata gtaaccgatt tcaacaagtg aaaattccct
     6301 atttttacac tttcttttct aaaacagtct atattttatt tcaaactgta ttatattttt
     6361 gaaaaaataa agtccttttt tctttttttc agaaaaaagg gtataataaa agaaaataag
     6421 cagtaacact caatggaaat cgaaaagcaa actaggaagc tagccgcaga ttgctcaaaa
     6481 cactgttttg aggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtataa
     6541 aaaggtgcta ggcatgttga tttttccttt gttaaatgat ttgtcaagaa aaatcatcca
     6601 tattgacatg gatgcctttt ttgctgcagt ggaaatcagg gataatccta aactcagagg
     6661 aaaacctgtc attattggaa gcgaccctcg gcaaacaggt ggacggggag tcgtttctac
     6721 ctgtagttat gaggcaagag cttttggtgt ccattctgcc atgagttcca aggaagctta
     6781 tgaacgttgt ccccaggctg tctttatctc agggaattat gagaaataca agtctgtggg
     6841 actccagatt cgagctattt ttaagcgcta tacagatttg attgaaccca tgagcattga
     6901 cgaagcctat ttggatgtga cagaaaataa actcggtatc aagtcagcgg tcaaaattgc
     6961 tcgcctcatt caaaaagata tctggcaaga actccatcta actgcttccg caggcgtttc
     7021 ttacaacaaa ttcttagcta aaatggcgag tgattatcaa aaaccacatg gtttgacagt
     7081 gattctacct gaacaggctg aggattttct caaacaaatg gatatttcca aatttcatgg
     7141 agtaggaaaa aagacagtag aacgtcttca tcaaatgggc gtttttactg gtgctgattt
     7201 acttgaagtt cctgaggtaa ccctaataga ccgttttggt agactaggct atgatctgta
     7261 tcgaaaggct cgtggcattc acaactctcc agtcaaatcc aatcgcatcc gtaaatcaat
     7321 cggcaaggag aaaacctacg ggaagattct ccttgctgag gaagatatca aaaaagagct
     7381 gactcttcta tcagaaaaag tcgctctcaa tctacatcaa caagaaaaag ctggaaaaat
     7441 tgtcattttg aaaatccgct acgaggactt ttcaactctt accaaacgaa aaagtcttgc
     7501 tcaaaaaaca caagatgcta gtcagataag ccaaatagcc ctgcaactct atgaagaatt
     7561 aagcaagaaa gaaagaggtg tccgcctatt ggggattacc atgactggat tttaaagctc
     7621 aatgaaaatc aaagagcaaa ctaggaggct agccgcaggc tgctcaaaac actgttttga
     7681 ggttgcagat aaagctgacg cggtttgaag agattttcga agagtataaa accttgaaga
     7741 gttgcccctt caaggttttt cttatacaaa taaacggaca aaactgtaaa gtagcaaaac
     7801 actaccaagc acgatacggt atttaccaaa aagggtgaag tcgtgttttt tcacatagct
     7861 ggtcaagaag cgaatagcca ccatgctgac cgcaaaagct actcccatcg cgaccaagag
     7921 caaaaacaat tgcccaaagc tcaagagttc tccggctttc acaaatttga aaatctttaa
     7981 ggcactagct ccaaacataa caggaatccc aagatagaag gtaaattctg tcacaactga
     8041 acgactggtt ccatttaaca aaccaccgac aatcgttgca cctgaacggc tagtccctgg
     8101 taaaagagca agaacttgga agagtccgat atagaaagcg gtcgtataag gaagcttgtc
     8161 caactctgtt acacttggct cgatagcacg cgctttattg cgcttttcca aatagatgaa
     8221 ggcaaccccg tagataatca acatgagagc aactgaaacc atgttatgga agtgggtatc
     8281 aaaccaatca tcaaatttaa agacaccaag taaaggtaaa gtagcaatca agaccttcaa
     8341 ccatagtctc caagtcttac gaacttcctg tttgtcctta gtcggtttaa aaggattgag
     8401 cttgttaaaa taaatcacca taactgctaa aatagcacca agctgaatca cgacattaaa
     8461 catggacata aaggcttcat tttgattttg gtattggatg aattcctctg ctaaaatcaa
     8521 gtgacctgta ctggaaatcg gcaaccattc cgtaattcct tcaacaatcc cgaagaagat
     8581 agattttaaa atttcaataa gatacataga ttactcccta tattataatt agcgcagtta
     8641 gctactgcca aagcccaagt ggtatacttg gaataagcca ctgtggatta gttcatttcc
     8701 tccaatcgct tgacgatttc cgaaaggctc taaccacagc ttttgtttca attggtaatg
     8761 agtttgataa cgcatagacg tttgatctcg tctaaggtaa caaggcaaaa aattcgtgga
     8821 taaccaagta gacttgaaat actatatctg gaggtactcc catgctttat gtgggcattg
     8881 atatcgctaa aaataaacac gatgttacag ccttgaatgt tccaggaaaa actgttctta
     8941 aaccactcac tttttcaaat aataaagctg gttttgaact cttagatctg tctcttcgac
     9001 agctcaacca agactgtctc atcgctct
//
LOCUS       DBERDS010000064         8865 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.064, whole genome shotgun sequence.
ACCESSION   DBERDS010000064 DBERDS010000000
VERSION     DBERDS010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.064"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            129..1622
                     /locus_tag="ACL73E_001855"
     CDS             129..1622
                     /locus_tag="ACL73E_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGS0801779.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..2162
                     /locus_tag="ACL73E_001856"
                     /pseudo
     CDS             1635..2162
                     /locus_tag="ACL73E_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            2174..2679
                     /locus_tag="ACL73E_001857"
                     /pseudo
     CDS             2174..2679
                     /locus_tag="ACL73E_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840532.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            2811..3047
                     /locus_tag="ACL73E_001858"
     CDS             2811..3047
                     /locus_tag="ACL73E_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGS0801780.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            3044..3457
                     /locus_tag="ACL73E_001859"
     CDS             3044..3457
                     /locus_tag="ACL73E_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGS0801781.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            3575..4540
                     /gene="xerA"
                     /locus_tag="ACL73E_001860"
     CDS             3575..4540
                     /gene="xerA"
                     /locus_tag="ACL73E_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGS0801782.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            4506..5144
                     /locus_tag="ACL73E_001861"
     CDS             4506..5144
                     /locus_tag="ACL73E_001861"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGS0801783.1"
                     /translation="MSSIHTKNSSLKSKSRFNEMFGENKIFESIDNLFDIIDGDRGKN
                     YPKSDELFSEEYCLFLNTKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRG
                     TVGNVAYYDELIKYKHLRINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQ
                     LPITKLKKILLPLPPLALQNEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            5174..8524
                     /locus_tag="ACL73E_001862"
     CDS             5174..8524
                     /locus_tag="ACL73E_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGS0801784.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYCATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISDQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT         3039 a         1337 c         1781 g         2708 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga ccagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt ttgtgagatt ttatctggtt
     1681 acgcttttaa atcatcacaa tttaatgata acaaaattgg tctcccctta atacgaattc
     1741 gagatgtaga aagaggtttt tctgatacct actttgaagg aacttatccc gaagaatatc
     1801 ttattaaaaa tggagactta ttgattacaa tggatggcag ttttatattg aaaaaatggg
     1861 agggggattt agcgctactt aatcaacgtg tctgtaaaat taaaattacg gataaaagtg
     1921 tagatgaagg ttatatatct tggttgattc ctaaattttt aaaagaaatt gaagataaga
     1981 ccccttttgt tacagtgaaa catctttcag tagctaaaat aaaagatatc tcatttgtat
     2041 tgcctaataa actagaacaa aagctaattg caaaaaaact aaatacgata agtcaaattt
     2101 atgattttcg taaaattcaa tcagaaaaat ttaacgagct cgtcaaatcc cgatattccg
     2161 aggaggtggt tgcatgaaga aagtgaaatt agggcaagtg gctactttta tcaatgtaaa
     2221 cctcaagatt ggtcatctga agggaaagag attatcagaa tacagaatct gactaaaact
     2281 tcaaaaggga taaattatta ttcgggtacg attgataaaa aatacattgt tgaagctggt
     2341 gatattctta tttcgtggtc gggtacatta ggggtttttc agtggtgtgg aagatccgca
     2401 gtgttaaatc agcacatttt taaagtggtt tttgataaga tagatataga taaatcgtat
     2461 tttaaatatg ttgttgaaaa aggtttacaa gatgctgtaa aacatactca tggttccaca
     2521 atgaaacatt taactaaaaa atattttgat aatattatgg tttcatatac aaatttggga
     2581 gagcaacaaa gaattgcaag tgagctggat ttgttaagca agctgatttt aaggagacaa
     2641 gaacaacttg aagagcttaa tctacttgta aaatcacaat tggcaatcca aaaatctctg
     2701 gaagaacttg aaactttgaa gaaatctctg atgcaggagt attttggctg atattctgcc
     2761 attgtaatta cggtaatgat ttgttataat acttcaaagg aggaaatcag atggtagtaa
     2821 aaacaagaaa acaaggaaat tcaatcacca ttacgattcc aagtgaattt aatattccaa
     2881 gtggtgttaa atacgaagcg aaattgttac caagtggtga gattatcttt actcctgaag
     2941 aattggggca gcaggtttct tatgtatctg atgatgcctt tgacttaaat ttagataaaa
     3001 tatttgacga atacgacgat gttttcaaag ctttggtgga aaaatgacaa tctatctgac
     3061 agaaaagcaa attgaaaaaa taaatgcttt agcaattcaa cggtattctc caaatgagaa
     3121 aattcaaaca gttagttctt ctgccttaaa tatgattgtg aacttaccag aacaatttgt
     3181 ctttgggaag tctctttatc caacaatttt tgataaagca acgatactat ttgtccaatt
     3241 gataaagaag catgtttttg ctaatgctaa taaaagaact gctttcttcg ttttggtcaa
     3301 atttttacaa ttaaacggct atcgtttttc tgtaacggta gaagaagcag taaaaatgtg
     3361 tgtaaccatc gcagtagaag ctttaactga tgaaaaaatg acaagctact ccaaatgggt
     3421 ttctgaacat tctgttagag aaaaggtcaa aaagtaacct agtatgctgg atttgaatga
     3481 gcacaagaaa ataaatgaac agacaatatt agaattctgt aatgcagaaa ctgatattgt
     3541 ctctttttat tgatgaataa gaaagtgaga aattatggaa tcaaaagtta caattatcat
     3601 gcaagaaatg ttacctcttt taaataatga acaattacta gcgttgagag agagtttaga
     3661 acatcatcta gtagacggaa aaaagcagca gaagtattcg aataataacc tgttgcaact
     3721 atttattacc gccaagcagg tagagggctg tagctcaaaa acaattcgtt attaccagag
     3781 gacgattgaa aacttgttta atgctattaa agagtctgtg acacaactca caacagatga
     3841 tttaaggagt tatttagcaa attaccagtc tgaaaaggat tgtagtaagg caaatttaga
     3901 caatattagg cgtatattgt cttctttttt tgcttggctt gagcaagagg aatatatcat
     3961 taaaaatccc attcgacgga taaagaaaat taagactgag caaaatgtga aggaaactta
     4021 tactgatgaa catttggaaa ttatgcgtga taactgtgaa aatttgagag atttggcaat
     4081 aatagaccta ctagcatcga caggtatgcg tgtaggggag cttgtacagt tgaatcgttc
     4141 agatattgat tttgaaaaca gagagtgtgt tgtctttggt aaaggaaaga aggagagacc
     4201 agtatatttt gatgctcgga cgaaaattca tttaagaaat tatcttaacg acagaaaaga
     4261 tagtcaccct gctctttttg taacgctagt tggaaaagcc cagagacttg gaattgctgg
     4321 tgtagagatt cgcttaagaa agttaggaga caaactcggc atacaaaagg ttcacccaca
     4381 taagttcaga agaactttag cgactaaggc aattgataaa ggtatgccta tcgaacaagt
     4441 ccaaaaactg ctaggtcata gcaagattga cacaaccctg gcctatgcca tggtcaatca
     4501 aaataatgtc aagcattcac accaaaaatt catctcttaa aagcaaatcc cgatttaacg
     4561 agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg
     4621 gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat
     4681 ttttaaatac aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca
     4741 ctaaaacaaa ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga
     4801 caacaagagg tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt
     4861 tacgtataaa ttcaggtatg gtaatattac gtcccaagac accaaatcta aatcagaaat
     4921 ttattatcca tgttttaagg aataataatt atagtcgagt gatatcagga agtgctcagc
     4981 ctcagttacc aattacaaaa ttaaaaaaaa tacttctccc cctcccccca ctagccctcc
     5041 aaaatgagtt cgcagacttt gtagtccagg tcgacaaatc acaatttgct tgtgagatag
     5101 ctataaaagt gtggagaaat agcttgaaat ttagtataat atagctaaac tatttgttta
     5161 aagtgagaaa aaaatgggaa attttagctt tcttttaaaa aatgacgaat atgaatcttt
     5221 ttcaaaacct tgcattgaag ctgaaaatat gattgctaca tcaactgtgg ctactgcctt
     5281 tatggcgcgt cgtgctttgg agcaggctgt ccattggata tatagtcacg attcatattt
     5341 agaagctccc tattgtgcta ctctatcttc tttagtatgg gatgatgatt ttagggatat
     5401 cgtagattct gaactccaca agcagatagt tctgttgatt cggtggggaa accatgctgc
     5461 tcatggtggt gaaattaagg aacgagaagc gattttagct ttacatcatt tgtatcagtt
     5521 tgttaatttt atcgattatt gttacagcaa tgaatttgtg gagcgttatt ttgatgagaa
     5581 gtgtttacca ctttcagcaa acatcaaata ccgagaaact ccacaatcta tgataaagtt
     5641 acaagacagt ttaccagaac tgcctgattt tcatgaacag atggctgctc agtccgtaga
     5701 agttcaagag acttatactg aaaaacgtga gactgcagcg caacggcaag atgtgccttt
     5761 ccatattgaa caattatctg aggcagagac aagaaagctc tttattgata tcgatctccg
     5821 tttagcagga tggatatttg aagaaaactg tcgtgttgag atagccgttg atggtctcaa
     5881 gcacggttca ggaattggtt actgtgacta tgtactttat ggtaaaaatg ggaaaatttt
     5941 agcgattgtg gaggctaaaa aagcctctgt caatccagaa gtaggggaag tacaggtcaa
     6001 agaatatgct gaagctttgg agaaacatat cggctatcag ccaatttgct ttattacaaa
     6061 tgggttgaag cactatatac ttgatggtcc gaaccgccgc cagattgcag gcttttactc
     6121 tcaagaagaa ttgcaattag tgatggatag acgtcatctt caaaaaccgc ttgaggatat
     6181 ttctagtaaa attagggacg atatttccgg gcgtcactac caaaaacatg ccattgcaag
     6241 cgtttgtgaa gctttctcta atcatcgtag acaggcactt ttggttatgg caactggggc
     6301 ggggaaaact cgtacagcag tttctctagt tgatatctta tcacgtcata actgggtaaa
     6361 aaacgttctc ttcttagccg atagaacttc cttggttaag caagcctatg attcgtttag
     6421 aaaattactc ccagatcttt ccgtttgtaa cttcttagaa gataaagaag gagctcaatc
     6481 aagtcgtatg gtcttttcaa cttatccgac catgattgga gcgattagtg atcaagaaga
     6541 agtaaatcaa cgccctttta ctgttgggca ttttgacctt atcataattg acgaatctca
     6601 ccgttctatt tatcagaaat acaagtccat ttttgattat tttgatgcaa ggattgtagg
     6661 cttaacagct actccgcgtc aagatttaga taaaaacacc tatggattct ttaatttgga
     6721 gaatggggtt ccaacatatg catatgattt ggaagaggct gttaaagacg gatatttagt
     6781 agcctatcat tctatcgaaa ccaaactgaa actacctacg gatggtctac attatgatga
     6841 tttgtccgaa gaagaaaagg aacattttga tagcaaattt gaagacgata gctgtgaaaa
     6901 agatattgat gggagtgtgt ttaattcctt tattttcaat aaaagtacag tagaaattgt
     6961 tttaaatgaa ctcatgacaa gaggaattca gacagcctcg ggtgatgaaa ttggtaaaac
     7021 tattattttt gctaaaaatc atgaccatgc ggaatatatc agaggtattt ttaacaaccg
     7081 ctatcctgaa aaagggagcg actatgctca ggtgattgat tatagtatta agcattatca
     7141 gaccttgatt gatgatttta aaattaagga gaagtatcct caaattgcga tttctgtcga
     7201 tatgttagat acaggtattg atgtaccaga ggttgttaat ttagtcttct tcaagaaagt
     7261 acgctctaaa actaagtttt ggcagatgat tggtcgagga acccgtctat gtaaagattt
     7321 atttggacct gagcaggata aggaaaactt cttggtattt gattatgggg acaattttga
     7381 ttattttcgt gcagatccaa gagatggaga gggtcgtcac attgtttcgt tgactcagcg
     7441 tttatttaat atcaaagtgg acttgattcg agaacttcag ggacttcaat accaagaaga
     7501 tcagtttgcg agagcatacc gtcagcagct tgtctcggaa cttcaaggtc gtatagagag
     7561 cttaaatgag ttggacttca gggttcgtat ggttttagat acagtttata gctataggaa
     7621 attggaaagt tggcagaatc taactgctgt tacaagtgaa accattcaaa aaaatctctc
     7681 tccgctttta tttgatgaag ataaagaaga tgagatggcc aggagatttg atttgtggtt
     7741 gcttcatatt cagttggggc aactgacagc taaatcttcc actgttcata tttcccaagt
     7801 gatgaagacg gctagagctc tttctgctat tggcaatatc ccgcaggttt ttgagcaggc
     7861 tgaaattatc aggaaagtac aggagcctga attttggaaa gaagttaact tgtctgattt
     7921 ggaaaaaatt cgtcttgcta ttcgagattt attacagttt ttggataaaa cagaccgtaa
     7981 accctactat gttaactttg aagatcgtat actctccact gttcacgaga ccacagcatt
     8041 tttgcaggtc aacgatcttc ggtcttacaa tgaaaaagtt gagcattatt tgaaaactca
     8101 tctggatgag gagtccattt ctaagctata ccataataaa aagttgacat ctgatgatat
     8161 gcttgcactt gaaaaattgc tctgggaaaa attaggtagt aaagcagact accaaagtca
     8221 ttatgaaaat aaggcaattc cgagattggt tcgtgagatt attggcttag atagagagtc
     8281 tgccaatcgt attttttcta aatttttgtc ggatgagaat cttaatgcca ggcagatttc
     8341 atttgtaaaa ttgattgtag actacattgt agaaaatggt tttttagaga cgaaagtgtt
     8401 aacgcaagag ccgtttaaat cttatggttc tgttcaacta ctcttccaac accaactacc
     8461 agtacttcgt aatattgttc aaatcattga acttatcaat aatcgagctg gagaagcggc
     8521 ttaaattcta aagtgattgc catgctgaga ctcatttaaa attaaaaaga gtagaaattt
     8581 atgctatata tgagaagttt tattaggaag aatgtcatcg ttttcctaga atacagtatc
     8641 agttgttaag tggttgataa atttcaaagt agatacttgt accacgatgt ttgttgatcg
     8701 agttattaac aaaagagcta ctttgatttt aaagaaatag aaaacaaaaa gctgagcaag
     8761 aattcaattg caggagaaaa tgaaataata ctcaatgaaa atcaaagagc aaactaggaa
     8821 actagctgca ggctgctcaa aacactgttt tgaggttgta gataa
//
LOCUS       DBERDS010000065         8477 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.065, whole genome shotgun sequence.
ACCESSION   DBERDS010000065 DBERDS010000000
VERSION     DBERDS010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8477
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.065"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..116
                     /locus_tag="ACL73E_001863"
     CDS             <1..116
                     /locus_tag="ACL73E_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGS0801785.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="ACL73E_001864"
     CDS             140..1063
                     /locus_tag="ACL73E_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HGS0801786.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDEKFNLLYEQDGKISPDKGITIEVENEIYYILGSSIYRITIGESVEETC
                     IGNFDFQLESGYGCYFDGHLFFGFQESYLFNIETQELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYSLKKDKWEKLEFELPSSVLGASSIQINESGLLILGGFNE
                     IVYNKAVIDLATPGYREEYFSKGRDFFNWNRSMRILDLETGKVKIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="ACL73E_001865"
     CDS             1145..2773
                     /locus_tag="ACL73E_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGS0801787.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDFSESGKEKVFYL
                     SGFLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGDFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLSKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2883..3833
                     /locus_tag="ACL73E_001866"
     CDS             2883..3833
                     /locus_tag="ACL73E_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801788.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFASGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3850..4701
                     /locus_tag="ACL73E_001867"
     CDS             3850..4701
                     /locus_tag="ACL73E_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801789.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4714..5643
                     /locus_tag="ACL73E_001868"
     CDS             4714..5643
                     /locus_tag="ACL73E_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801790.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSTIAKSLMKLHDITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDPYAS
                     LNPTKKIYNSFDEPMIVHNIGNKEERFERMKEALKMVNVPVEYLERYPHEFSGGQRQR
                     LCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGVVKY
                     MCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKENEV
                     EFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            5653..7062
                     /locus_tag="ACL73E_001869"
     CDS             5653..7062
                     /locus_tag="ACL73E_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801791.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDTKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            7067..7555
                     /locus_tag="ACL73E_001870"
     CDS             7067..7555
                     /locus_tag="ACL73E_001870"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HGS0801792.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            7824..8225
                     /locus_tag="ACL73E_001871"
     CDS             7824..8225
                     /locus_tag="ACL73E_001871"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGS0801793.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLTRSYPQTKDSCSLERSLGSKFG"
     gene            8158..8304
                     /locus_tag="ACL73E_001872"
                     /pseudo
     CDS             8158..8304
                     /locus_tag="ACL73E_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
BASE COUNT         2875 a         1195 c         1573 g         2834 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 tgagaaattt aatcttctat atgaacaaga tggaaaaatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tggtgaaagt gtagaagaaa cctgtatcgg gaattttgat ttccaactag agagtggtta
      481 tggttgttat tttgatggcc acttattctt tggatttcag gaaagttatt tgttcaatat
      541 tgagactcaa gagcttttta aaaaatctga cttcccagtt tctggtagag gccaaggttt
      601 gtcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatagtt taaaaaaaga taagtgggaa aaacttgagt tcgaattacc
      721 aagctcagtt ctaggagcat caagtataca aataaatgaa agtggtttat taatacttgg
      781 tggctttaat gaaattgttt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatat ttttctaaag ggagagattt ctttaattgg aatcgtagca tgcgaatact
      901 agatttagag acaggtaagg tcaagattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat ttttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gttttcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatggatt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 tgactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa gtaaaaaacc aattgatatc ctattctatc gctactttat
     2041 cgctaactta gcaggtgtcg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tggtttattg aatcatgtat ctctcactct tgttttttca ggagaaatta
     2881 aaatgaaaaa atatattcta aaaaaagtat tattcatgat tcctatgttg ttgattatta
     2941 gctttttagt attcattgca ctagatttaa caccagcaga tccattgaca tatatggtat
     3001 ctccagatat ggctagtagt gcagaacaaa tcgaaaagct aagacagcaa ttaggtttaa
     3061 atgatccagt attagttcgc tatggaagat ggctttggca attactccat ggtgattttg
     3121 gatacagtat tgtaaatggt aacccaattt ccaaaattgt aggacaagca ttgcctgcaa
     3181 cttttgaatt agcttttgtg tcattaatta tttcaacaat tgttggtatt gtaattgggg
     3241 ttatatcagc cgttaaacaa aatggtatta tcgataatgt tgctcgtttt ctagctgtta
     3301 tcggaactgc gattccacaa tttttctttg gtattttaat tttaaacttc tttgcaattc
     3361 agttaagaat tttacctatt ggtggtagat ttgccagtgg agattttaca tttattaata
     3421 gagttgaaca cttaattcta ccagtaatgg ctatgtcaat tgcattggta gctgctttaa
     3481 tgagatacac acgtaattct atgttggatg tttttaatgc agattatgtt aaaacagctc
     3541 gtgcaaaagg tgttcctgaa tggaaagttt attttaaaca catatttaga aatgctatgc
     3601 gaccaatttt agtgttattg attttccgtc taccaatgtt aattggtgga tcagtaatta
     3661 tcgagagtgt cttttcttgg cctggaattg gttctatcat cctatctagt gtaacagcag
     3721 gtgactatcc tgtaattatg attaccacat taatgatttc tgtcgtagtg ttatttgcta
     3781 gtctacttgt agatattatg gctgcaatat tagacccacg tattcgttat taggaaggag
     3841 gtcaatgtta tgaaacctat gcctttatgg aaaagaaatt tgaaaaaatt ctataataac
     3901 aaattggcct ttatcggctt tatatgcttc atgctaattc tattagcatg tattctagca
     3961 cctttattga caacctattc tccagatgtt gttgatttag gatctatgaa ccgtcctcct
     4021 tcagcaaaac acattctggg aacagataaa ctaggtcgtg acgtatttgc tcgaatccta
     4081 tatggtggtc gagtttcaat tcaagtcggg atgtatggag cgatttgtgg agcggttatt
     4141 ggtactgtac ttggtggtat tgctggatat tttggtggga aaattgatgc tcttctagtt
     4201 cgtctagcag aattattctt aacattcccg aatatgattg tcattctctt gctttcaagt
     4261 atttttggac aaggtgtatt caatcttatc ttcgtattct cagtaatggg ttggatgaca
     4321 acgttccgaa tggttcgtaa tgagttcatg tctttgaaac aagaaacata tgtggatgta
     4381 tgtagagctt ttggtttttc tgacagtcga attatcttta ataatatttt aagaaatgct
     4441 atctcaccag taattgtatc gttgtcttta aacgttgctg gtttcattct cagtgaggca
     4501 ggtcttagtt tcttaggagt aggtgttcct tctgatattc ctacttgggg aaatatcata
     4561 aatgctgcca aaacagccga tgttattaaa aatagttggt ggttgtggtt agttccaggg
     4621 tcaatcatta ctcttttcgt tctttctatc aactttattg gtgatggatt acgagatata
     4681 atggatccga aacaacagta ggaggttgac aaaatgaatc aaacagtttt agatgtaaaa
     4741 aacttaaaaa ctgaattcat cactgataaa aaagcatttc cgattattaa agatgtaaac
     4801 ttcactttgg aaagagggaa agttttaggg attgttggtg aatctggatg cggtaagagt
     4861 acgattgcga aatcattaat gaaactccat gatattacag atggtgaaat caatattgat
     4921 ttgaatggga aaactcaaaa tatttatgga attaaacgta aggaagattt ggatttccgt
     4981 aagaaagttc aaatggtatt ccaagatcct tatgcatcat tgaacccaac taagaaaatt
     5041 tataattcat ttgatgaacc gatgattgtc cataatattg gaaacaaaga ggaacgcttt
     5101 gaacgtatga aagaagcctt gaagatggta aacgtgccag ttgagtactt ggagcgttat
     5161 cctcatgaat tttcaggcgg acaacgtcaa cgtttatgta ttgctcgtgc cctttgtatg
     5221 aaaccagaaa ttttaatttt agatgaacct gtttcagcat tagatctatc tgtacaagcg
     5281 caagttttga attatcttgt tgaaatccaa aataaagaag atttgactta tgtatttatt
     5341 tctcatgacc taggtgttgt gaaatacatg tgtgactatc tatatgttat tcataaagga
     5401 cgtattgtag aagctggttc tcgagaagat atctacaata acccaatgca tatttacact
     5461 aaaaaactat tagctgctat tccagaagtt gattatcact tcaaagaggc attggcaaca
     5521 aaacgtaaag aaaatgaagt tgaatttaaa gcacagtacc atgaatttta tgatgaagat
     5581 ggtcgtgctt atgatcttaa gcaggtttca ccaacacatt ttgtagcgtt aaaaccagaa
     5641 taggtggtaa atatgaaatt aaataaaaaa atatatttct ttgataaagg aatttttaat
     5701 ccttatcgaa tgagtaatgt aaaattaaaa gttaatcagg cagtaaagga taaagaaatt
     5761 ttcttcactg aggaaaaacc atgggaaatt cgttttgata acagttatcc aaatgttttc
     5821 tttgatgatt tagcaggtgt ttatcgttgc tactattcta catttactga tgatgaggag
     5881 tctgaaaaat actctttaga ggagcgtaag gaacgtcaat atctacctcg tgcgaagcgt
     5941 attgtttcac tttgttatgc tgaaagtaaa gatggtgtta actgggtgaa accaaatcta
     6001 ggtattacag aatttcgagg atcaactgaa aataatatta tcggacattt tttacatggt
     6061 acatctgttt ttctagataa acatgacgca gatgaaaatc gtcgttataa aatgtttaca
     6121 aagattgatt acggtaacgg tgttcatttc attgctgtag cattttcaaa agatggtcta
     6181 cactttgatg aatacattaa agtaccaaac ttcaatccac gtgcagacac tcataaccat
     6241 atcatatatg atgaagcatt aaatcgctat gtgctaatta ctcgtacttg gagagattca
     6301 ttgcgcttgc cgtgtgtatc tacgagtgct gatttcatta actggactcc aattcaagaa
     6361 attttgaatg tctgtgatta tgaaaatcaa atttattcta tgcctatttt taaacgtggc
     6421 gattatatac taggtttagc ttcagttttc catgaaggag atcaactgaa caagaattac
     6481 gatacagtgg accttcaatt gacttatagt tatcgtcatg ttggttggca ttatctaaac
     6541 actgatactc cacttattcc tcgtggtaaa ggtcaatatg gtgatggaga atttgactgt
     6601 ggatgtatct attcttctgc accagttact atcggtgacc gtacttattt ctactacatg
     6661 ggaggaaatg gacaacatac aaacttccgt gaaacaagct tgtctcgtgc ttatattgag
     6721 aaagatcact ttgcatattg ggatactaaa cgtccagaat atccaggtgt tttgtatacc
     6781 aatggattta ttttcctcaa tgatcaagtt taccttgatg cagatattgc agctggaggc
     6841 tttgtaacaa ttgaattgtt cgagaataat cacactccaa tggaaattac agcttccctt
     6901 gaaaaaatag aagatggtcg ctatcaagtg ttattcagcg aacctttacc tcgaactcaa
     6961 actcgactga aaattagctt taaaaatgct aaaatctacg caatcgaagg aaatttagat
     7021 attttcagaa ttgaatcaga caatgctcta ttgagggggt aagattatga aatatgattt
     7081 atatgataat tgtattgaac ttctaaaaga acgcgaagtt acaattgaag atatggcagc
     7141 gttagtaata ttttcacaac aaaaatatta ccctgaatta actcttgacg acgcttcata
     7201 tgcaattcaa cgtgtactaa aaaaacgtga agttcagaat gtaattatga caggaattga
     7261 gttagataag ttagctgaag cacaaaaact atctccagaa tttcaaaaga ttatggagaa
     7321 agataatcca ttgtatggga ttgatgaagt aatcgtctta tcgatattga atttatatgg
     7381 ttctattgcc tttacaaatt atggctattt agataaatta aaaccactga ttttagaaag
     7441 attgaatgag aatcacgaag gtgtttgtaa tgtatttcta gatgatattg ttggtgcaat
     7501 agccgcagca gcatgtagta aaattgcaca caatcatgct agtgatgaaa tataactatt
     7561 gaatttagta tcgtaaataa taaagcgttt ggtttctaga ttattgtcat tcaaattgga
     7621 taatgataaa tctagaaacc aaatatattt tccgcataaa atgagggatt atatatctca
     7681 cttttttaca ctagaatagt gcatctctac ttctaaaaca ttgttagaaa tcgatttgac
     7741 tgtcctgatt gatttgcact gttcttattt cattttacta taatttagtg tgagtaaaat
     7801 ataataataa aggagttaaa acaatgacag taattaataa atttgtttta atggagcaag
     7861 caaaaaaagt tttaaaaaat gcttactgtc cgtattccaa atttcctgta ggtgcagcaa
     7921 ttttatttaa agatggtaaa gtaattacag gagcaaatat agaaaatgta tcgtttggtg
     7981 taactaactg tgcagaacgt agtgctattt tttatggggc ttctcaagga tatagaaaag
     8041 gagatattct tgcgattgct gttgcaggtg aaactgaaga ctacttacca ccatgcaaca
     8101 tttgtcgtca agttatggta gaattttgtg agcctgatac cttagtcttt ctattaacaa
     8161 gaagctatcc tcaaaccaaa gattcgtgca gccttgaaag aagtcttggt tccaagtttg
     8221 gctgagaaca caagattaga atttgctcat catcaaaaca ctgctggtat gcttggagcc
     8281 tactatcatt ttaaaataaa ataaatttaa tatttacttt actaaattag tgtattcttc
     8341 ctactttaat tagagaatga tttaagttct ctttaaaaat caaaagagtc taggacaaaa
     8401 tagttctcaa tcacaaaaaa gctaaagatt tccaattgtg gaactctagc tttttaattt
     8461 tgagtcgttc tcttatt
//
LOCUS       DBERDS010000066         7330 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.066, whole genome shotgun sequence.
ACCESSION   DBERDS010000066 DBERDS010000000
VERSION     DBERDS010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.066"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            226..6657
                     /locus_tag="ACL73E_001873"
     CDS             226..6657
                     /locus_tag="ACL73E_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGS0801794.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPHEVVLADTSNSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDNNTSNEEARIKE
                     DSNQSQGDNAHSSANKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLTGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYINGKEYTSFDDIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REEHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
BASE COUNT         2892 a          982 c         1399 g         2057 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggagt ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctca tgaggtagtc
      301 ttagcagaca catctaactc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatctcaag gagataatgc acactcgtct gcaaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccagtcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcta tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaaggt
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctgata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttacggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacactgatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataacgaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagtga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatataaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa tagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagagcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcaaggaa ttaagtagcg tttggttgct taattccttt ttatttggaa
     6961 ggaagttttt cgtaaccgcc caataacgaa gtctattgga cggttacgat atgatcactg
     7021 acttcgtcag tcttatctac aacctcaaaa ctgtgttttg agcaacctgc ggctagcttc
     7081 ttagcttact ctttgatttt cattgagtat tagaacagaa aaaatgcttg gagtatttgt
     7141 ttgtgtgttt gtttttatat aacaaactat aaacaaaaca aaaatataaa aaaagagaca
     7201 aaaaagaaca gaaagtaatt gacaacggtt tcatatagtg ttatacttat ggcataaagt
     7261 taatggaaag aagggaaaac cttatggtat tagattattt ctttgacaaa aaccttgtgt
     7321 tttgcttaga
//
LOCUS       DBERDS010000067         6801 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.067, whole genome shotgun sequence.
ACCESSION   DBERDS010000067 DBERDS010000000
VERSION     DBERDS010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.067"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..369
                     /locus_tag="ACL73E_001874"
     CDS             <1..369
                     /locus_tag="ACL73E_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGS0801795.1"
                     /translation="VSGRRYQRISLVAGLTNGELIVPMTYEEMMTSDFFEVWFQKFFL
                     PTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLK
                     KVLPSCNTFYEAFLSCSCFN"
     gene            430..1392
                     /locus_tag="ACL73E_001875"
     CDS             430..1392
                     /locus_tag="ACL73E_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS0801796.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPIESLCYE"
     gene            1569..2576
                     /gene="gap"
                     /locus_tag="ACL73E_001876"
     CDS             1569..2576
                     /gene="gap"
                     /locus_tag="ACL73E_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGS0801797.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2644..3519)
                     /locus_tag="ACL73E_001877"
     CDS             complement(2644..3519)
                     /locus_tag="ACL73E_001877"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGS0801798.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWNEIVNPGDVCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3606..5801
                     /gene="pbp2a"
                     /locus_tag="ACL73E_001878"
     CDS             3606..5801
                     /gene="pbp2a"
                     /locus_tag="ACL73E_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGS0801799.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5854..6006
                     /gene="rpmG"
                     /locus_tag="ACL73E_001879"
     CDS             5854..6006
                     /gene="rpmG"
                     /locus_tag="ACL73E_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGS0801800.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6016..6192
                     /gene="secE"
                     /locus_tag="ACL73E_001880"
     CDS             6016..6192
                     /gene="secE"
                     /locus_tag="ACL73E_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGS0801801.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6247..6783
                     /gene="nusG"
                     /locus_tag="ACL73E_001881"
     CDS             6247..6783
                     /gene="nusG"
                     /locus_tag="ACL73E_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGS0801802.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2114 a         1187 c         1472 g         2028 t
ORIGIN      
        1 gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa tggtgagtta
       61 atcgttccaa tgacttacga agagatgatg acgagcgact tttttgaagt atggtttcag
      121 aagtttttct taccaacatt aaccacacca tcggttatta ttatggataa tgcaagattc
      181 catagaatgg gtaagctaga actcttgtgt gaagagtttg ggcataaact tttacctctt
      241 cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat caaaaagcac
      301 ctcaaaaagg tattaccaag ttgcaatacc ttttacgagg cttttttatc ctgctcttgt
      361 ttcaattgac tatagttcac ggatacagtt gggaaagaag ctattaaata tttggagagt
      421 ccttttggga tgaacatgtc aaatattact atagatgggc aagaaatgga tctgagtcaa
      481 acgatgcctt cttatgctca agtagtgagt ctttatgatg atacaagtat ctctgttagt
      541 aataatgaga cggacaaagt gttggctgga tccctctata ctgatacaaa tgaacaggga
      601 ttaacgattc caagcagttt actaaaaaat tggaatgaac agacaggaaa aaatttgaca
      661 gctaatgatc ttattggcaa atcagtctca gccagcattg tagaaagtgc tgccgaaact
      721 agtaagattg ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga agatgacatg
      781 gaggacagca acagtttcat gctgtctcat caaatggaaa cgattttgaa agaggctgga
      841 tttacgaaag ctgtatctta ttttatcttg gaactcaaag atccatcaca gacaaaagta
      901 gtaacagaag aattacagaa aaataagaag tatactgtgc tttctcaaca gagagttctt
      961 gatattgtga ttacctttat tcgtgttatt cagggattat tgattgtgct ttcatcacaa
     1021 gctattgtgg tagcagcggt tatgattggt atcattattt acatcaatat catgcaacgt
     1081 tccaaggaaa taggtgtcat gaaagcagtt ggttatcaga atcgtgatgt caaaggaatt
     1141 tttatttacg aggctatctg gattgtaggc atcgccttgc tgctggcatt tttggttgca
     1201 caaggggtgg gaagtttggc gaatgcgatt gtaagtcact tttacccatc catcactaag
     1261 gtttttgaat taaatctttt atctgtttta ggaactctag ttttcgctct attacttggt
     1321 tatgtctcag cctacttccc ggcgcgtaag attagtaaaa tggatcctat agaatcgtta
     1381 tgctatgaat agtaagggat tccttggttt acagtcttaa aaagaaacta acatagaaaa
     1441 acaatggcca tacttgcaat tcaactcaaa tagttgtata ataggtttgt tgaaaggtga
     1501 tttgtagtga ttcaagttac tcttttcaca ataaaaattt catgattttc ataaggagga
     1561 aatcactaat ggtagttaaa gttggtatta acggtttcgg acgtatcggt cgtcttgctt
     1621 tccgtcgtat ccaaaacgta gaaggtgttg aagttacacg catcaacgac cttacagatc
     1681 cagttatgct tgcacacttg ttgaaatacg acacaactca aggtcgtttc gacggtactg
     1741 ttgaagttaa agaaggtgga tttgaagtta acggtaaatt catcaaagtt tctgctgaac
     1801 gtgatccaga acaaatcgac tgggctactg acggtgtaga aatcgttctt gaagctactg
     1861 gtttctttgc taagaaagaa gcagctgaaa aacaccttaa aggtggagct aaaaaagttg
     1921 ttatcactgc tcctggtgga aacgacgtta aaacagttgt attcaacact aaccacgacg
     1981 ttcttgacgg tactgaaaca gttatctcag gtgcttcatg tactacaaac tgcttggctc
     2041 caatggctaa agctcttcaa gacaactttg gtgttgttga aggattgatg actactatcc
     2101 acgcttacac tggtgaccaa atgatccttg acggaccaca ccgtggtggt gaccttcgcc
     2161 gtgctcgcgc tggtgctgca aacatcgttc ctaactcaac tggtgctgca aaagctatcg
     2221 gtcttgtaat cccagaattg aatggtaaac ttgacggatc tgcacaacgc gttccaactc
     2281 caactggatc agttactgaa ttggtagcag ttcttgaaaa gaacgttact gttgatgaag
     2341 tgaacgcagc tatgaaagca gcttcaaacg aatcatacgg ttacacagaa gatccaatcg
     2401 tatcttcaga tatcgtaggt atgtcttacg gttcattgtt tgacgcaact caaactaaag
     2461 ttcttgacgt tgacggtaaa caattggtta aagttgtatc atggtacgac aacgaaatgt
     2521 catacactgc acaacttgtt cgtactcttg aatacttcgc aaagattgct aaataattct
     2581 tgagttgata gaaagcaagg ctttgtggtc ttgctttttt atatggaaaa atggatgaca
     2641 cgatcatcca ttctttttta attctttttc aaatgtattt gaaagggtag tgaaagttag
     2701 cctctctaaa gtaagtgggt gggtaaagga aagtcggaag gcatgaagca taagccggct
     2761 tgtctttgat ttactattat agagagggtc tcccaggata ggaagattat gatgcaaaag
     2821 gtgcacacga atctgatggg ttcgccctgt ctttagcttg caatgagcca aggaagtctt
     2881 gtttgagaat tgctttaatc tgcttacatg cgtttcagca tattgcccat tttttgcatc
     2941 aactattctt tttctacgat catggcgatc acgtccaatt ttgtctctga aaacaagttc
     3001 ttttctgttg atatttccat caactagagc ccaatattct ctagaaatct cttttttctc
     3061 caataagcga ttgagaatgg gcaggataaa aggatttttg gcaaagagaa ctaagccact
     3121 ggtttccatg tccagacgat gaacgacata gcaggtttgg ccaacatagg tactgacatg
     3181 gttaagaagg gcaatttcgt ttggttgatt accatgcgtt ttcatcccct ctggtttgtt
     3241 tacaataatc aagtgttgat cttgataaac ttcctgcact aagtctgggt tgccccaagg
     3301 gatcgtcttt tgggaataat cttcctcgtc aaaagtcaac tggcaaacat ctccaggatt
     3361 tacgatttcg ttccagtgga cttcttcttg atttatcaaa atatgtttct tgattctcaa
     3421 aaaatgacgg atttttctag ggatgaggag ttgttcctca agtaattgct ttaccgtcat
     3481 ttgaggtaga gaggcgggta atgtaaatgt gaattgcata cagatattgt aacaaaaaaa
     3541 gccctatttg gataggaaat agctaaattc ttgtcttcct atgatgaaga tgataaaata
     3601 aacgcatgaa attagataaa ttatttgaga aatttctttc tctttttaaa aaagaaacaa
     3661 gtgaactaga ggactctgat tctactatct tacgtcgctc tcgtagtgat cgaaaaaaat
     3721 tagcccaagt aggtccgatt cgaaaattct ggcgtcgtta tcatctaaca aagattatcc
     3781 ttatactagg tttgagtgca ggattgctag ttggaatcta tttgtttgct gtagccaagt
     3841 cgaccaatgt caatgatttg caaaatgcct tgaaaactcg gactcttatt tttgaccgtg
     3901 aagaaaaaga ggctggtgcc ttgtctggtc aaaagggaac ctatgttgag ctgactgaca
     3961 tcagtaaaaa cttgcagaat gctgttattg cgacagaaga ccgttctttc tataaaaatg
     4021 acgggattaa ctatggccgt ttcttcttgg ctattgtcac tgctggacgt tcaggtggtg
     4081 gctctaccat tacccaacag ctggctaaaa acgcctattt atcgcaggat caaactgttg
     4141 agagaaaagc gaaagaattt ttccttgcct tagaattaag caaaaaatat agtaaggagc
     4201 aaattctaac catgtacctt aacaacgctt attttggaaa tggtgtgtgg ggtgtagaag
     4261 atgcgagtaa gaaatacttt ggagtttctg catcagaagt gagtctggat caagctgcga
     4321 ctctggcagg gatgctcaag gggccggaac tgtataatcc cttgaattcc gtagaagatt
     4381 ctactaatcg gcgcgatact gtcttgcaga atatggttgc agcaggatat attgataaaa
     4441 accaagaaac cgaagctgct gaagttgata tgacttcgca attgcacgat aagtatgaag
     4501 gaaaaatctc agattaccgt tacccctctt attttgatgc ggtggttaat gaagctgttt
     4561 ccaagtataa tctaacagag gaagagattg tcaataatgg ctaccgcatt tacacagagc
     4621 tggaccaaaa ctaccaagca aatatgcaga ttgtttatga aaacacatcg ctatttccga
     4681 gggcagagga tggaacgttt gctcaatcag gaagtgtagc tctcgaaccg aaaacagggg
     4741 gagttcgtgg agttgtcggt caagttgctg acaatgataa aactggattc cggaatttca
     4801 actatgcaac ccaatcaaag cgtagtcctg gttctacaat taagccttta gttgtttata
     4861 cgccagcagt tgaagcaggc tgggctttga ataagcagtt ggataaccat accatgcagt
     4921 atgacagcta taaggttgat aactatgcag ggatcaaaac gagtcgagaa gttcctatgt
     4981 atcaagcctt ggcagaatcg cttaatctac ctgctgttgc cactgttaat gatttgggtg
     5041 tcgacaaggc ttttgaggca ggcgaaaaat tcggactcaa catggaaaag gtcgaccgtg
     5101 ttcttggtgt cgccttggga agcggtgttg aaaccaaccc tcttcaaatg gctcaagcat
     5161 acgctgcctt tgcaaatgaa ggtttaatgc ctgaagctca ttttattagt agaattgaaa
     5221 atgctagtgg acaagttatt gcgagtcata aaaattcaca aaaacgggtg attgataagt
     5281 ctgtagctga caagatgacc agtatgatgt tggggacttt caccaacggt accggtatta
     5341 gttcatcgcc tgcagactat attatggcag ggaaaactgg aacaactgaa gcagttttta
     5401 atccggagta cacaagtgac caatgggtaa ttggttatac tccggatgta gtgattagcc
     5461 actggcttgg ctttccgacc actgatgaaa atcactatct agctggctct acttcaaacg
     5521 gtgcagctca tgtctttaga aacattgcca ataccatttt accttatacg ccaggaagta
     5581 cctttacggt tgaaaatgct tataagcaaa atggaattgc accagccaat acaaaaagac
     5641 aagtacaaac caatgataat agccagacag atgataattt gtctgatatt cgagggcgtg
     5701 cgcaaagtct agtagatgag gctagccggg ctatctcaga tgcgaagatt aaggaaaagg
     5761 ctcaaacaat atgggattcg atagtcaatc tatttcgcta agatgcttgt caaagcctag
     5821 ctttcttgtt ataatggata agatggaggc gttatggcac taaaaaaagc aagcctagct
     5881 tgtgcggttt gtggttcgag aaactattca atcaagatca gcggaaaccc caagcctaca
     5941 cgactagaag taaataaatt ttgtaagcat tgtggcaagt acactacaca cagagaaacg
     6001 agataggaga gagcgatgcg ttttattgga gatattttta gacttcttaa agacacaaca
     6061 tggccaactc gcaaggaaag ctggagagat tttcgttcta tcatggaata cacagctttc
     6121 tttgtagtaa ttatttacat ttttgaccag ttgattgttt caggtttgat tcgatttatt
     6181 aacatttttt agaagattag tggagttaat tacactagaa atcttctatt tatgaaagga
     6241 aatatcatgg atagttttga taaaggatgg tttgttttac aaacttattc tggttatgaa
     6301 aataaggtga aagaaaatct attacaacgt gcacaaacct acaatatgtt ggataatatt
     6361 ttacgcgttg aaattccaac acaaacagtg caagttgaaa aaaatggaaa gagaaaagaa
     6421 gtagaagaaa atcgctttcc aggttatgtt cttgtagaaa tggtcatgac agatgaagct
     6481 tggtttgttg ttcgaaacac accaaatgtt acaggatttg tcggatcaca cgggaacaga
     6541 tcaaaaccaa ctccattatt ggaacaagaa attcgtgaca ttttggtatc tatgggacaa
     6601 actgttcaag aatttgattt cgatgttgag attggtcaaa ctgtacgtat tattgatggt
     6661 gcttttgcag actacactgg taagattaca gaaattgata ataacaaagt gaaaatgatt
     6721 atctctatgt ttggtaatga cacagttgca gaagtaaacc taaaccaaat cgcagaatta
     6781 taaccctgag agaggctgga g
//
LOCUS       DBERDS010000068         6248 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.068, whole genome shotgun sequence.
ACCESSION   DBERDS010000068 DBERDS010000000
VERSION     DBERDS010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6248
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.068"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            170..370
                     /locus_tag="ACL73E_001882"
     CDS             170..370
                     /locus_tag="ACL73E_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801803.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATQAVLLDAQKAPEDSALTE"
     gene            395..811
                     /locus_tag="ACL73E_001883"
     CDS             395..811
                     /locus_tag="ACL73E_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGS0801804.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1042..1749
                     /gene="ccdA2"
                     /locus_tag="ACL73E_001884"
     CDS             1042..1749
                     /gene="ccdA2"
                     /locus_tag="ACL73E_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGS0801805.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLTLASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1760..2317
                     /gene="sdbB"
                     /locus_tag="ACL73E_001885"
     CDS             1760..2317
                     /gene="sdbB"
                     /locus_tag="ACL73E_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGS0801806.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2691..4082
                     /locus_tag="ACL73E_001886"
     CDS             2691..4082
                     /locus_tag="ACL73E_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGS0801807.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4225..5142
                     /gene="adcAII"
                     /locus_tag="ACL73E_001887"
     CDS             4225..5142
                     /gene="adcAII"
                     /locus_tag="ACL73E_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGS0801808.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5150..>6248
                     /gene="phtB"
                     /locus_tag="ACL73E_001888"
     CDS             5150..>6248
                     /gene="phtB"
                     /locus_tag="ACL73E_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGS0801809.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEERIA
                     RIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPS"
BASE COUNT         1905 a         1150 c         1318 g         1875 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagc ctatatgtac tattctagtt tcaatatacc ataactgctc ctagtcaacc
      121 tgcaagtcct gtcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagttag accaacgctt gaaagctttg gcaacagtat ctgatccaaa
      301 aatcgatgca acccaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgccttgg actctctcaa
      421 agatgtgaaa gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgcaaaaca
      481 aggaacggaa gatagtaagg attcagataa gatgactgaa acaaactcag ttccggcagg
      541 agtgattgtg gtcagtctac ttgccctcct aggcgtgatt gccttctggc tgattcgccg
      601 taagaaagag tcagaaatcc agcaattaag cacggaattg atcaaggttc taggacagct
      661 agatgcagaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac
      721 ccttgatttc gtgaaagaag aaaatggctc agcagagaca gaaactaaac tagtagagga
      781 gcttaaagca atccttgaca aactcaagta aaacatgatt tatgaaatgt cagacctaaa
      841 agacattttc gttcacaaaa gcagtgacga gtaatccttg tcgttgcttt ttggctattt
      901 tgggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgcccgatac
      961 gattttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatt
     1021 attaagaaag ttggttcttt attggaaacg atagtatttt taatctctgt ttttctagca
     1081 ggtgttttat cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt
     1141 ttattggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg
     1201 tcaggcttga ttcgaacact ttgctttatc gctggtatct ctctcatttt ctttattcta
     1261 ggctttggtg ctggttactt tggtcatatt ctctatgcaa attggtttcg atatgtcatg
     1321 ggagctatta ttatcatttt gggtcttcac cagatggaaa tttttcattt gaagaaatta
     1381 gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagctttt
     1441 ttacttggta ttacctttag ctttggttgg acaccttgta ttggtccagt tttaagttct
     1501 gttttagcac ttgcggcttc tggaggcaat ggtgcttggc aaggagcgat ttatactctc
     1561 atttacactc tgggcatggc ccttcctttc ttggtcttga cactagcttc aggtctagtc
     1621 atgccatatt ttagtaaaat caagcgtcat atgatgctac taaagaaaat tggtggtttc
     1681 ctcattgttt taatgggaat tttgttacta ttaggacaag taaatgttct agctggaatt
     1741 tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc tcttgtcatt
     1801 agttgtattg atggcctgtg gtgaggaaga aactaaaaag actcaagcag cacaacagcc
     1861 aaaacaacaa acgactgtac aacaaatttc tgttggaaaa gatgctccag actttacatt
     1921 gcaatccatg gatggcaaag aagttaagtt atctgatttt aagggtaaaa aggtttactt
     1981 gaagttttgg gcttcatggt gtggtccatg caagaaaagt atgccagagt tgatggaact
     2041 agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc attgcaccag gaattcaagg
     2101 tgaaaaaact gttgagcaat tcccacaatg gttccaggaa caaggatata aggatatccc
     2161 agttctttat gataccaaag caaccacctt ccaagcttat caaattcgaa gcattcctac
     2221 agaatattta attgatagcc aaggaaagat tggaaagatt caatttggtg ctatcagtaa
     2281 tgcggatgca gaagcagcat ttaaagaaat gaactagaat cgataaaatc tgattacaag
     2341 atgtagtcag attttggtaa cttctaaaac taacttccag tttcccacaa cttagctttt
     2401 agtatgagaa aaacgcgtga catcagtgga aatccgtctt agactaactt ccactggttt
     2461 tctttttctt gatatataag ggttcaaaag cgaaaagact cagaaaaagt gcacgacaaa
     2521 tagccctaaa acagagtcgt cttagagtaa cttccagttt tgggagagag atggaagtta
     2581 ctttgagaag ttacggtagt cagatttttt tagaaaaaca ttttataaat attcacatat
     2641 ctcctatatt tatggtaaaa tagaattatc agtttatttt ggagtcaaag atgaatatat
     2701 ttagaacaaa gaatgttagt ttagataaaa cagagatgca taggcatttg aagttatggg
     2761 atttgatttt gctgggtatc ggagccatgg tagggacagg cgtctttaca atcacaggta
     2821 ctgcagctgc aacacttgct ggcccagccc tagtgatttc aatcgttatt tctgccttgt
     2881 gtgtgggatt atcagccctc ttttttgcag aatttgcctc gcgagtaccc gctacaggag
     2941 gtgcctatag ttacctctat gctatcttag gagaattccc tgcctggttg gctggttggt
     3001 taaccatgat ggagttcatg acagccatat caggcgtagc ttcgggttgg gcagcttatt
     3061 ttaaaggctt gctctctcaa tatgggatag cccttcctca ggctttaaat ggtaccttta
     3121 atcctcaagc agggacattt gttgatttat tgcctattct tgtcttggtc ttggtgactt
     3181 cgcttgtttt actaaatgcc aaggcagcct tacgctttaa ttcgattcta gttattttga
     3241 aattttccgc tttagctctc tttgttttag taggaatttg gaatattaag tttgataatt
     3301 ggagcaattt tgctccttac ggctttggac aaatctatgg agctagtact ggtattatgg
     3361 ctggtgcgtc cttgatgttc ttcggttttt tgggatttga atccatctct atggctgtag
     3421 atgaagtcaa gactcctcaa aaaaatattc ctagagggat tgtcttatcg ctttctatcg
     3481 taaccattct ctatgccttg gtgacccttg ttttgactgg tgtggttcac tatagtcatt
     3541 taaatgtcga tgatgccgtt gcctttgccc ttcgtagtgt tgggattagt tgggcagcca
     3601 actatgtgtc attagtggct atcttgacct tgattacagt ttgtatttcg atgacctatg
     3661 ccctatcgcg tatgatttac agtttagcac gtgacggctt agtgcctgct gcctttaagg
     3721 aactgacgaa gactagcaag gtaccaaaga atgctactat cttgacaggt ctagcttcag
     3781 cagtagcagc aggaatgttc ccactagcca gtattgcagc ctttttaaat atttgtacct
     3841 tagcctactt gatcatgctg gcttatggtc tgattcgctt acggaaagaa aaaggaatgc
     3901 ccaaagctgg ggaatttaaa acaccattgg tacctctgtt accaatttta tcgatcatca
     3961 tttgtttatc cttcatgtta cagtataata tgaatacctg gattgctttc ctagttgcgt
     4021 tgttagtagg aagtattatt tacttcactt atggctataa gcattctacc atagaagaat
     4081 aaagtgaaag tctattgagt tgttgacact cagcagattt ttatatgtga aagaaatttc
     4141 aaattttttc taaaaatatc ttgacagatt aaattttcag gagtagaata tttactagtt
     4201 aattaaatgg ttaaggagtt gttcatgaag aaacaaaatt tatttttagt cctgttaagt
     4261 gtctttcttt tgtgcttggg ggcttgtggt caaaaggaaa gtcagacagg aaaggggatg
     4321 aaaattgtga ccagttttta tcctatctac gctatggtta aggaagtatc tggtgacttg
     4381 aatgatgttc ggatgattca gtcaagtagt ggtattcact cctttgaacc ttcggcaaat
     4441 gatatcgcag ccatctatga tgcagatgtc tttgtttacc attctcatac actcgaatct
     4501 tgggcaggaa gtctggatcc aaatctaaaa aaatccaaag tgaaggtctt agaggcttct
     4561 gagggaatga ccttggaacg tgtccctgga ctagaggatg tggaagcagg ggatggagtt
     4621 gatgaaaaaa cgctctatga ccctcacaca tggctagatc ctgaaaaagc tggagaagaa
     4681 gcccaaatta tcgctgataa actttcagag gtggatagtg agcataaaga gacttatcaa
     4741 aaaaatgcgc aagcctttat caaaaaagct caggaattga ctaagaaatt ccaaccaaaa
     4801 tttgaaaaag cgactcagaa aacatttgta acacaacata cagccttttc ttatctagcg
     4861 aagagatttg ggcttaatca acttggtatt gcaggtatct ctcctgaaca agaaccaagt
     4921 ccacgacaac taacagaaat tcaggaattt gttaagacct ataaggttaa aacgattttt
     4981 acagaaagta acgcttcttc aaaagtagct gaaactcttg tcaaatcaac aggtgtgggt
     5041 cttaaaactc tgaatccttt agagtcagac ccacaaaatg acaagaccta tttagaaaat
     5101 cttgaagaaa atatgagtat tctagcagaa gaattaaagt gaggaaagaa tgaaaatcaa
     5161 taaaaaatat ctagcaggtt cagtggcagt ccttgcccta agtgtttgtt cctatgaact
     5221 tggtcgtcac caagctggtc aggttaagaa agagtctaat cgagtttctt atatagatgg
     5281 tgatcaggct ggtcaaaagg cagaaaattt gacaccagat gaagtcagta agagagaggg
     5341 gatcaacgcc gaacaaattg ttatcaagat tacggatcaa ggttatgtga cctctcatgg
     5401 agaccattat cattactata atggcaaggt tccttatgat gccatcatca gtgaagaact
     5461 tctcatgaaa gatccgaatt atcagttgaa ggattcagac attgtcaatg aaatcaaggg
     5521 tggctatgtg attaaggtag acggaaaata ctatgtttac cttaaagatg cggcccatgc
     5581 ggacaatatt cggacaaaag aagagattaa acgtcagaag caggaacgca gtcataatca
     5641 taactcaaga gcagataatg ctgttgctgc agccagagcc cagggacgct acaccacaga
     5701 tgatggttat atctttaatg cttctgatat cattgaggac acgggtgatg cttatatcgt
     5761 tcctcacggc gaccattacc attacattcc taagaatgag ttatcagcta gcgagttagc
     5821 tgctgcagaa gcctattgga atgggaagca gggatctcgt ccttcttcaa gttctagtta
     5881 taatgcaaat ccagctcaac caagattgtc agagaaccac aatctgactg tcactccaac
     5941 ttatcatcaa aatcaagggg aaaacatttc aagcctttta cgtgaattgt atgctaaacc
     6001 cttatcagaa cgccatgtag aatctgatgg ccttgttttc gacccagcgc aaatcacaag
     6061 tcgaacagcc agaggtgtag ctgtccctca tggtaaccat taccacttta tcccttatga
     6121 acaaatgtct gaattggaag aacgaattgc tcgtattatt ccccttcgtt atcgttcaaa
     6181 ccattgggta ccagattcaa gaccagaaca accaagtcca caaccgactc cggaacctag
     6241 tccaagtc
//
LOCUS       DBERDS010000069         6125 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.069, whole genome shotgun sequence.
ACCESSION   DBERDS010000069 DBERDS010000000
VERSION     DBERDS010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6125
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.069"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            279..1824
                     /locus_tag="ACL73E_001889"
     rRNA            279..1824
                     /locus_tag="ACL73E_001889"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1876..1948
                     /locus_tag="ACL73E_001890"
     tRNA            1876..1948
                     /locus_tag="ACL73E_001890"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1909..1911,aa:Ala,seq:tgc)
     gene            2073..4974
                     /locus_tag="ACL73E_001891"
     rRNA            2073..4974
                     /locus_tag="ACL73E_001891"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5051..5166
                     /gene="rrf"
                     /locus_tag="ACL73E_001892"
     rRNA            5051..5166
                     /gene="rrf"
                     /locus_tag="ACL73E_001892"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            5171..5243
                     /locus_tag="ACL73E_001893"
     tRNA            5171..5243
                     /locus_tag="ACL73E_001893"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5204..5206,aa:Val,seq:tac)
     gene            5246..5318
                     /locus_tag="ACL73E_001894"
     tRNA            5246..5318
                     /locus_tag="ACL73E_001894"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5279..5281,aa:Asp,seq:gtc)
     gene            5343..5415
                     /locus_tag="ACL73E_001895"
     tRNA            5343..5415
                     /locus_tag="ACL73E_001895"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5376..5378,aa:Lys,seq:ttt)
     gene            5421..5502
                     /locus_tag="ACL73E_001896"
     tRNA            5421..5502
                     /locus_tag="ACL73E_001896"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5455..5457,aa:Leu,seq:tag)
     gene            5521..5593
                     /locus_tag="ACL73E_001897"
     tRNA            5521..5593
                     /locus_tag="ACL73E_001897"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5554..5556,aa:Thr,seq:tgt)
     gene            5616..5687
                     /locus_tag="ACL73E_001898"
     tRNA            5616..5687
                     /locus_tag="ACL73E_001898"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5648..5650,aa:Gly,seq:gcc)
     gene            5695..5780
                     /locus_tag="ACL73E_001899"
     tRNA            5695..5780
                     /locus_tag="ACL73E_001899"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5729..5731,aa:Leu,seq:taa)
     gene            5790..5863
                     /locus_tag="ACL73E_001900"
     tRNA            5790..5863
                     /locus_tag="ACL73E_001900"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5824..5826,aa:Arg,seq:acg)
     gene            5879..5952
                     /locus_tag="ACL73E_001901"
     tRNA            5879..5952
                     /locus_tag="ACL73E_001901"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5913..5915,aa:Pro,seq:tgg)
     gene            5958..6031
                     /locus_tag="ACL73E_001902"
     tRNA            5958..6031
                     /locus_tag="ACL73E_001902"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5992..5994,aa:Met,seq:cat)
     gene            6045..6118
                     /locus_tag="ACL73E_001903"
     tRNA            6045..6118
                     /locus_tag="ACL73E_001903"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6079..6081,aa:Ile,seq:cat)
BASE COUNT         1677 a         1264 c         1789 g         1395 t
ORIGIN      
        1 acacgggttc gaatcccgta cggactatgg tatgttgcgt caggaccact tgatgaaaaa
       61 aagtttaaaa aaacttaaaa atcttcaaaa aagtgttgac aagtgaaagt ggctgtgata
      121 tactaatata gttgtcgctt gagagaagca agtgacaaag acctttgaaa actgaacaag
      181 acgaaccaat gtgcagggcg ctacaacata agttgtagta ctgaacaatg aaaaaacaat
      241 aaatctgtca gtgacagaaa tgagtgagaa ctcaaacttt taatgagagt ttgatcctgg
      301 ctcaggacga acgctggcgg cgtgcctaat acatgcaagt agaacgctga aggagaagct
      361 tgcttctctg gatgagttgc gaacgggtga gtaacgcgta ggtaacctgc ctggtagcgg
      421 gggataacta ttggaaacga tagctaatac cgcataagag tggatgttgc atgacatttg
      481 cttaaaaggt gcacttgcat cactaccaga tggacctgcg ttgtattagc tagttggtgg
      541 ggtaacggct caccaaggcg acgatacata gccgacctga gagggtgatc ggccacactg
      601 ggactgagac acggcccaga ctcctacggg aggcagcagt agggaatctt cggcaatgga
      661 cggaagtctg accgagcaac gccgcgtgag tgaagaaggt tttcggatcg taaagctctg
      721 ttgtaagaga agaacgagtg tgagagtgga aagttcacac tgtgacggta tcttaccaga
      781 aagggacggc taactacgtg ccagcagccg cggtaatacg taggtcccga gcgttgtccg
      841 gatttattgg gcgtaaagcg agcgcaggcg gttagataag tctgaagtta aaggctgtgg
      901 cttaaccata gtaggctttg gaaactgttt aacttgagtg caagagggga gagtggaatt
      961 ccatgtgtag cggtgaaatg cgtagatata tggaggaaca ccggtggcga aagcggctct
     1021 ctggcttgta actgacgctg aggctcgaaa gcgtggggag caaacaggat tagataccct
     1081 ggtagtccac gctgtaaacg atgagtgcta ggtgttagac cctttccggg gtttagtgcc
     1141 gtagctaacg cattaagcac tccgcctggg gagtacgacc gcaaggttga aactcaaagg
     1201 aattgacggg ggcccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga
     1261 accttaccag gtcttgacat ccctctgacc gctctagaga tagagttttc cttcgggaca
     1321 gaggtgacag gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc
     1381 cgcaacgagc gcaaccccta ttgttagttg ccatcattta gttgggcact ctagcgagac
     1441 tgccggtaat aaaccggagg aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc
     1501 tgggctacac acgtgctaca atggctggta caacgagtcg caagccggtg acggcaagct
     1561 aatctcttaa agccagtctc agttcggatt gtaggctgca actcgcctac atgaagtcgg
     1621 aatcgctagt aatcgcggat cagcacgccg cggtgaatac gttcccgggc cttgtacaca
     1681 ccgcccgtca caccacgaga gtttgtaaca cccgaagtcg gtgaggtaac cgtaaggagc
     1741 cagccgccta aggtgggata gatgattggg gtgaagtcgt aacaaggtag ccgtatcgga
     1801 aggtgcggct ggatcacctc ctttctaagg ataaggaact gcgcattggt cttgtttagt
     1861 cttgagaggt cttgtggggc cttagctcag ctgggagagc gcctgctttg cacgcaggag
     1921 gtcagcggtt cgatcccgct aggctccatt ggtgagagat caccaagtaa tgcacattga
     1981 aaattgaata tctatatcaa atagtaacaa gaaaataaac cgaaaacgct gtagtattaa
     2041 taagagttta tgactgaaag gtcagaaaat aaggttaagt taataagggc gcacggtgga
     2101 tgccttggca ctaggagccg acgaaggacg tgacaaacga cgatatgcct tgggtagctg
     2161 taagtaagcg atgatccagg gatttccgaa tgggggaacc caacaggtaa tacctgttac
     2221 ccacatctgt taaggatgtg aggaggaaga cgcagtgaac tgaaacatct aagtagctgc
     2281 aggaagagaa agcaaaagcg attgccttag tagcggcgag cgaaacggca gaagggcaaa
     2341 ccgaagagtt tactcttcgg ggttgtagga ctgcaatgtg gactcaaaga ttatagaaga
     2401 atgatttggg aagatcagcc aaagagagta atagcctcgt atttaaaata gtctttgtac
     2461 ttagcagtat cctgagtacg gcgggacacg tgaaatcccg tcggaatctg ggaggaccat
     2521 ctcccaaccc taaatactcc ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg
     2581 aaaagcaccc cgggagggga gtgaaataga acctgaaacc gtgtgcctac aacaagttcg
     2641 agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt acgttatgat
     2701 gcgaggttaa gttgaagaga cggagccgta gggaaaccga gtctgaatag ggcgccttag
     2761 tatcatgacg tagacccgaa accatgtgac ctacccatga gcaggttgaa ggtgcggtaa
     2821 gacgcactgg aggaccgaac cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc
     2881 ggagaaattc caaacgaact tggagatagc tggttctctc cgaaatagct ttagggctag
     2941 cgtcgacatt agagattctt ggaggtagag cactgtttgg gtgaggggtc catcccggat
     3001 taccaatctc agataaactc cgaatgccaa tgaattatgg tcggcagtca gactgcgagt
     3061 gctaagatcc gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc ccaaaataat
     3121 tgttaagtgg aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc
     3181 tattcattca aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac
     3241 cggggctaaa acaatttacc gaagctgtgg atacctttat aggtatggta ggagagcgtt
     3301 ctatgtgtga tgaaggtata ccgtgaggag tgctggaacg catagaagtg agaatgccgg
     3361 tatgagtagc gaaagacagg tgagaatcct gtccaccgta agactaaggt ttccagggga
     3421 aggctcgtcc gccctgggtt agtcgggacc taaggagaga ccgaaaggtg tatccgatgg
     3481 acaacaggtt gatattcctg tactagagta tgtagtgatg gagggacgca gtaggctaac
     3541 taaagcagac gattggaaga gtctgtctaa gcagtgaggt gtgaattgag tcaaatgctt
     3601 aattctataa cattgagctg tgatggggag cgaagtttag tagcgaagtt agtgacgtca
     3661 cactgccaag aaaagcttct agcgtttaaa catactctac ccgtaccgca aaccgacaca
     3721 ggtagtcgag gcgagtagcc tcaggtgagc gagagaactc tcgttaagga actcggcaaa
     3781 atgaccccgt aacttcggga gaaggggtgc tgacttaaag tcagccgcag tgaataggcc
     3841 caagcaactg tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg
     3901 tgacgcctgc ccggtgctgg aaggttaaga ggagtgctta gcgtaagcga aggtatgaat
     3961 tgaagcccca gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt
     4021 cgggtaagtt ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac
     4081 tcggtgaaat tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc
     4141 atggagcttt actgcagttt gatattgagt gtctgtacca catgtacagg ataggtagga
     4201 gtctaagaga tcgggacgcc agtttcgaag gagacgctgt tgggatacta cccttgtgtt
     4261 atggccactc taacccagat aggtgatccc tatcggagac agtgtctgac gggcagtttg
     4321 actggggcgg tcgcctccta aaaggtaacg gaggcgccca aaggttccct cagaatggtt
     4381 ggaaatcatt cgcagagtgt aaaggtataa gggagcttga ctgcgagagc tacaactcga
     4441 gcagggacga aagtcgggct tagtgatccg gtggttccgt atggaagggc catcgctcaa
     4501 cggataaaag ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg
     4561 gaggtttggc acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt
     4621 tgggctgttc gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc
     4681 ggtccctatc cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac
     4741 cagagtggac ttaccgctgg tgtaccagtt gtcttgccaa aggcatcgct gggtagctat
     4801 gtagggaagg gataaacgct gaaagcatct aagtgtgaaa cccacctcaa gatgagattt
     4861 cccatgatta tatatcagta agagccctga gagatgatca ggtagatagg ttagaagtgg
     4921 aagtgtggcg acacatgtag cggactaata ctaatagctc gaggacttat ccaaagtaac
     4981 tgagaatatg aaagcgaacg gttttcttaa attgaataga tattcaattt tgagtaggta
     5041 ttactcagag ttaagtgacg atagcctagg agatacacct gtacccatgc cgaacacaga
     5101 agttaagccc tagaacgccg gaagtagttg ggggttgccc cctgtgagat agggaagtcg
     5161 cttagctcta gggagtttag ctcagctggg agagcatctg ccttacaagc agagggtcag
     5221 cggttcgatc ccgttaactc ccaaaggtcc cgtagtgtag cggttatcac gtcgccctgt
     5281 cacggcgaag atcgcgggtt cgattcccgt cgggaccgtt taaggtaacg caagttattt
     5341 tagactcgtt agctcagttg gtagagcaat tgacttttaa tcaatgggtc actggttcga
     5401 gcccagtacg ggtcatatat gcgggtttgg cggaattggc agacgcacca gatttaggat
     5461 ctggcgctta acggcgtggg ggttcaagtc ccttaacccg cattaagata taacaaatga
     5521 gccggcttag ctcagttggt agagcatctg atttgtaatc agagggtcgc gtgttcaagt
     5581 catgtagccg gcatttttag atagaagaaa acagtgcgaa cgtagttcag tggtagaaca
     5641 ccaccttgcc aaggtggggg tcgcgggttc gaatcccgtc gttcgcttag agaggccggg
     5701 gtggcggaac tggcagacgc acaggactta aaatcctgcg attggtaacg atcgtaccgg
     5761 ttcgattccg gtcctcggca taatatggag cacccttagc tcaactggat agagtacctg
     5821 actacgaatc aggcggttag aggttcgact cctctagggt gcatttttct atttaactcg
     5881 ggaagtagct cagcttggta gagtacttgg tttgggacca aggtgtcgca ggttcgaatc
     5941 ctgtcttccc gattcatggc ggtgtagctc agctggctag agcgtccggt tcatacccgg
     6001 gaggtcgggg gttcgatccc cttcgccgct ataatgatct tgtcggacct ttagctcagc
     6061 tggttagagc tctcggctca taaccgagtg gtcgtaggtt caagtcctac aaggtccatt
     6121 tgaat
//
LOCUS       DBERDS010000070         5698 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.070, whole genome shotgun sequence.
ACCESSION   DBERDS010000070 DBERDS010000000
VERSION     DBERDS010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.070"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            95..892
                     /locus_tag="ACL73E_001904"
     CDS             95..892
                     /locus_tag="ACL73E_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGS0801810.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSLLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1040..2299
                     /locus_tag="ACL73E_001905"
                     /pseudo
     CDS             1040..2299
                     /locus_tag="ACL73E_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2395..3669
                     /locus_tag="ACL73E_001906"
     CDS             2395..3669
                     /locus_tag="ACL73E_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGS0801811.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3681..>5698
                     /locus_tag="ACL73E_001907"
     CDS             3681..>5698
                     /locus_tag="ACL73E_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HGS0801812.1"
                     /translation="MEDDLNYENLMDDVTEAIKKFNLVIFIGAGVSIAQGYPNWNNYI
                     EHLIKYWQGQVLSVSGEKRLGREHHVVFDLISKSSISNKRKVDLVNYELKKVFGEDFE
                     KRRLDFEKGYFKNLLPYSIVNQTVESLASLNAIFITSNYDYEIENHIKRLKNAVVTIN
                     DLNEFTKNKNGKLQFGDVLHIHGTPDCDVKYFVSSSADYSKTYLKNRENFENLVTWFK
                     ETKPTVLFVGAGLEEDEILSLLCKDSKNYALMKSENTGNQRVDEHYRGVVEGFFSSEN
                     HTQIIWYGDEFEKLPLFVKKLVADINEKLGTHDFYNQWNNLLNPSINQEEYNKNLDSI
                     SNDFKYLSSVLDKVIENDNNQLDQLMLNALLRSETLTVIKKNFVLAFWRFIVKNIEKL
                     SDNEWDVIYKIIYEGSQNYFIDDVFFVYNYAIDNKISSFTNNNKLNELREIISKDGYI
                     VNSNFNKDKTLLGYWLVSAFEQQNRDLYIKEDSEVEVNLNYECVNKLMSILNNPEFLS
                     YNYYSIEHQLKEYDVVKFLYELVKSKKLFIEEEKFLESDSEDLISTILIQKLLVQLDN
                     EINLDLEFIKRLIDKIDFSNIHFGEELNTFIKEHRSIIREKNIEIPKKTYRNWISSLE
                     GGFVSQFSYLTQENLVEYDESRVLEILVNAEKEQRGSSFLEEKTINET"
BASE COUNT         1907 a          885 c         1149 g         1757 t
ORIGIN      
        1 atctactata aacttttatg aaatatagaa aacgcttcct aaaacctaaa gtttgtgata
       61 taattatcaa gaaaaaaaga tttaggagtt tattatggtt tcttcagaat ttatctcaaa
      121 gattgaattt gcttgcaata agaaagaaag tctttatagt caaagcaaat ttaagtatgc
      181 gattcgttcg atgttcgcag gtgcattttt aaccttcagt actgctgcag gtgcagttgg
      241 ggctgacttg attaataaaa ttgcaccagg tagcggacgc ttcctctttc cattcgtttt
      301 tgcttggggc ttggcctaca ttgttttttt gaatgccgag ttggtcactt caaacatgat
      361 gttcttgact gctggtagtt tattaaaaaa aatctcttgg agaaaaacag ctgagatttt
      421 actatactgt accttgttca accttatcgg agccttgata gcagggtggg gctttgctca
      481 ttcggcagcc tatgcgaatc tgacacacga tagtttcatc tcaggggttg tagagatgaa
      541 gttaggccgc tcaaatgaat tggtcttgct tgaggcgatt ttggcaaata ttttcgtaaa
      601 cattgccatt ctttcattta ttttggtcaa agatggtggt gccaaacttt ggcttgtgtt
      661 gtcagctatt tacatgtttg tattcttaac aaacgagcac attgcggcga actttgcttc
      721 tttcgcgatt gtgaaattca gtgttgctgc ggattcaatt gccaacttcg gtgttggaaa
      781 tatgcttcgc cactggggtg tgactttcat cggaaacttt atcggaggag gcctcttgat
      841 gggtcttcca tatgccttcc tcaataaaaa cgaagatact tatgtagatt aagaaaatga
      901 gcacgattga gtcgtgcttt tttcattttc aaaataagat aatagctatt tcttatatca
      961 aaatatagaa aactgatatt tgtaaactat aactcaaggt gctacaatat ccttaataaa
     1021 ataatatgga ggtcacctta tgactcgtga ttttaaattt gaaactctac aactacatgc
     1081 tggtcaagtt gtgactccag ctactaagtc tcgtgcagtg ccgatttatc aaacaacatc
     1141 ttttgttttt gatgacacgt aggaaggtgc tgatctgttt gccttgagga aaccagggaa
     1201 catttatact cgtatcacca atcctacaac agctgccctt gaaggtggtg ttgaagcgct
     1261 agcaacagca tcaggtatga ctgcagtgac ttatacgatt ttggcgcttg cccatgctgg
     1321 tgagcatgta gtggctgctt cgactattta cggtggaacc ttcaatcttt tgaaagaacc
     1381 ccttcctcgt tatggtatca caacaacctt tgtcgatgtt gataatttgg aggaagtaga
     1441 agcagctatc aaagacaata ccaagcttgt cttgattgaa accttggtta accccttgat
     1501 taatattcca gacctggaaa aactggcaga gattgctcat aaacatcaaa tcccacttgt
     1561 gtcagacaat acttttgcaa caccttattt gattaacgtc ttctctcatg gcgttgacat
     1621 tgccattcac tctgcgacta agtttatcgg tgggcatggt acaactattg gaggaataat
     1681 tgtcgatagt ggtcgttttg actggacggc ttcagggaaa ttccctcaat ttgttgacga
     1741 gagtccaagc tgccacaatt tgagctatac tcatgatgtg ggtgcagcag cctttattat
     1801 agctgttcga gttcaattgc ttcgtgatac aggtgcagcc ttgtcaccat tcaatgcttt
     1861 cctcttgcta caaagacttg aaaccctttc acttcgtgtg gaacgccatg tacaaaatgc
     1921 tgagacaatt gttgattttc ttgtcaacca tcctaaggta gaaaaggtaa attatccaaa
     1981 acttgcagat agtccttatt atgccttggc tgagaaatac ttgccaaaag gtgtcggttc
     2041 aatctttacc ttccacgtca aaggtgacga ggaggaagca cgcaaggtca ttgataattt
     2101 agaaatcttt tctgaccttg caaacgcggc agatgctaaa tcgcttgttg tccatccagc
     2161 aacaatcact cacggtcaat tgtcagaaaa agacctagaa gcagcaggtg tcacaccaaa
     2221 tcaaatccac ttgtctatcg gtcttgaaaa tgtagaagat ttgattgaag acttacgctt
     2281 ggccttggaa aaaatttaaa gtaaaagaag ataaacagtg ggttttgact cactgttttt
     2341 gattttccct caggcatgat ataatggtta cagaagtcta gaaagaggaa tgtaatgaac
     2401 gaaatcaaat gtcccaactg tggggaagtc tttacagtaa atgaaagcca gtatgctgaa
     2461 cttttgtccc aagtgagaac ggcagagttt gataaggaac tacacgatag gatgaggcag
     2521 gaactggcct tggctgagca aaaggctatg aatgagcaac agactaaact ggctcagaag
     2581 gatcaagaaa ttgcgcaatt gcagagtcaa atccaaaact ttgatacaga aaaagaattg
     2641 gccaagaaag aagttgaaca gacaagccat caggccttat tggctaagga caaggaagta
     2701 caggccttgg aaaaccagtt ggcgaccttg cgtttggagc atgaaaatca attgcaaaag
     2761 accctttctg acctagaaaa agaacgcaat caggtcaaaa atcagctcct actgcaagaa
     2821 aaggaaaatg agttgtcttt ggcttctgtt aagcaaaact acgaagccca gctcaaagca
     2881 gccagtgaac aagtcgagtt ttataagaat tttaaggctc aacaatctac aaaagcgatt
     2941 ggggaaagcc tagaacagta tgcagagagt gagtttaaca aggttcgtag tttcgccttt
     3001 ccaaatgctt actttgagaa ggataacaag gtctcttcgc gtgggtctaa aggggacttt
     3061 atcttccgtg agtgtgatga aaatggagtt gaaatcattt ctatcatgtt tgagatgaaa
     3121 aacgaagcgg acggaacaga gaagaagcac aagaatgcag atttttacaa ggaattggac
     3181 aaggaccgtc gggagaagaa ctgtgagtat gccgttttgg tgaccatgct tgaggctgat
     3241 aatgactact ttaacacagg gattgttgac gtcagtcacg agtatgaaaa aatgtatgtt
     3301 gttcgtcctc aattctttat ccaattgatt ggtctcttac gtaatgcggc gctaaattcc
     3361 ctaaaataca agcaggagtt ggccttggtt cgcgagcaaa atattgacat tacgcatttt
     3421 gaggaagact tggatgcctt taagctagct tttgctaaga actataattc agcttcgact
     3481 aactttggaa aagctattga tgaaatcgac aaggccatca aacgcatgga agaggttaag
     3541 aaattcctga ctacatctga aaaccaactc cgtctagcta acaacaaatt ggaagatgtc
     3601 tctgttaaaa aattgacccg gaaaaatcca acaatgaaag cgaagttcga agcattgaag
     3661 ggggagtgag gaaataagtt atggaagatg atcttaatta tgaaaatttg atggatgatg
     3721 taaccgaggc tataaaaaag tttaacttag taatttttat tggcgcagga gtttcaattg
     3781 ctcaaggtta tcctaattgg aacaattata ttgaacatct tattaagtat tggcaaggac
     3841 aagttttatc ggtaagtggt gaaaaaaggc ttggaagaga acatcacgta gtttttgatt
     3901 taattagcaa atctagtatt agtaataaac gtaaagtgga tcttgtaaac tatgaattaa
     3961 aaaaagtttt tggtgaagat tttgaaaagc gacgactaga ttttgaaaaa ggatatttta
     4021 aaaatctatt accatattca atagttaatc aaacagtaga atctttagca agtttgaatg
     4081 caatatttat tacttctaac tacgactatg aaattgaaaa tcatattaaa cgtttaaaga
     4141 atgctgtagt tactattaat gatctcaatg aattcactaa gaacaagaat gggaaactac
     4201 aatttggtga tgttctacat atccatggaa caccagattg tgatgtaaag tattttgtaa
     4261 gttcatccgc agattattca aaaacctatt taaaaaatag ggaaaatttt gaaaatttag
     4321 taacatggtt taaagagaca aaacctactg ttttatttgt tggagcaggt cttgaagaag
     4381 atgaaatttt atctttactt tgtaaagata gtaagaacta tgccttgatg aagtcagaga
     4441 acacaggtaa tcagagagtt gatgaacatt atagaggtgt tgttgaagga ttttttagct
     4501 cagaaaatca tactcagatt atttggtacg gagatgaatt tgagaaacta cctctttttg
     4561 taaaaaaatt agttgctgat attaatgaaa aattgggcac acatgatttt tataatcagt
     4621 ggaacaatct tttgaatcct tctataaatc aagaagagta taataaaaat ctagatagta
     4681 tttctaatga ttttaagtat ctaagctctg ttttagataa ggttattgaa aatgataata
     4741 atcaactaga tcagctaatg ttaaatgctc tgcttcggag tgaaactcta acagtaatta
     4801 aaaaaaattt tgtccttgca ttttggaggt ttattgttaa gaatattgaa aagttaagtg
     4861 ataatgagtg ggatgtgatt tataaaataa tttatgaagg ctctcaaaat tactttatag
     4921 atgatgtatt ctttgtctat aattatgcga tagataataa aatttctagt tttacaaata
     4981 ataataagct taatgaactg agagaaatta tatccaaaga tggatatatc gttaattcta
     5041 actttaataa agataaaact cttttgggtt actggctagt aagtgctttt gaacagcaaa
     5101 atcgtgattt atatataaag gaagatagtg aagtagaagt taacttaaat tacgaatgtg
     5161 ttaacaaatt aatgtccata ctaaataatc cagaattttt aagttataat tactactcta
     5221 tagagcatca attaaaagag tatgatgttg ttaaatttct ttatgagctt gtaaagtcca
     5281 aaaaattatt tattgaagag gaaaagtttt tagaaagtga ttctgaagac ttaataagta
     5341 ctatattaat tcaaaaattg cttgttcaat tggataatga aattaatttg gatttagaat
     5401 ttatcaagag gttaattgat aaaattgatt tttcaaatat tcactttgga gaggaattaa
     5461 acacttttat caaagaacat agaagtatta ttagagaaaa aaatattgaa ataccaaaaa
     5521 aaacttatag aaattggata tcttcactag aaggaggttt tgtttcacaa ttttcatatt
     5581 taactcaaga aaatcttgta gagtacgatg aatctagagt attagagata ttagtcaacg
     5641 ccgaaaagga acaaagaggt tcttcatttt tggaagaaaa gacgataaat gaaacgga
//
LOCUS       DBERDS010000071         5373 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.071, whole genome shotgun sequence.
ACCESSION   DBERDS010000071 DBERDS010000000
VERSION     DBERDS010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.071"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            72..548
                     /locus_tag="ACL73E_001908"
     CDS             72..548
                     /locus_tag="ACL73E_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801813.1"
                     /translation="MSRTYINIRLAYETKYWLECIQEEVQKKLDALINEQDIEELESI
                     ITNKLEKKDSLLGAVSITTFFKVSSSSVIEKAYNETKNYTTSEWREIARQMNLAKVKQ
                     NMEIGTLTPRLYLDNNIISELEKYQFLFKSDDMIRQVRMSYVIKMVAFAYYKKLFA"
     gene            719..1273
                     /locus_tag="ACL73E_001909"
     CDS             719..1273
                     /locus_tag="ACL73E_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801814.1"
                     /translation="MPKLLETEKYSLDSIIDGGKLRMISKFCPDLHGLRYEFKTSDSI
                     TKEYCKKIRQALRDSDPEGKSGKKCMMRYTIDILNVWNTLCRTRDFITGSLKADDVID
                     GKTGIYFFDVNTSNVITDDVIENVKINHKSLVRNVDEENIESISKEIPKGTDMYYYVL
                     YRLGLNRIKYNYLVKALAGAIQKD"
     gene            1549..1935
                     /locus_tag="ACL73E_001910"
                     /pseudo
     CDS             1549..1935
                     /locus_tag="ACL73E_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
     gene            1929..2051
                     /locus_tag="ACL73E_001911"
                     /pseudo
     CDS             1929..2051
                     /locus_tag="ACL73E_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            2055..3188
                     /locus_tag="ACL73E_001912"
     CDS             2055..3188
                     /locus_tag="ACL73E_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGS0801815.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYMTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            3229..3666
                     /locus_tag="ACL73E_001913"
     CDS             3229..3666
                     /locus_tag="ACL73E_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGS0801816.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVTTDEE
                     KAVAYLHDVIEDTTLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKTNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRTKKKS"
     gene            3874..4110
                     /gene="relB"
                     /locus_tag="ACL73E_001914"
     CDS             3874..4110
                     /gene="relB"
                     /locus_tag="ACL73E_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGS0801817.1"
                     /translation="MNNVVTTLISVQFSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKTISHEEMMRRYG"
     gene            4103..4834
                     /locus_tag="ACL73E_001915"
     CDS             4103..4834
                     /locus_tag="ACL73E_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGS0801818.1"
                     /translation="MAKIYAISDIHGYLDEFIDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEIYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLCYDTITQKYHFL"
     gene            complement(4945..5028)
                     /locus_tag="ACL73E_001916"
     tRNA            complement(4945..5028)
                     /locus_tag="ACL73E_001916"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4992..4994),aa:Leu,seq:caa)
     gene            complement(5038..5109)
                     /locus_tag="ACL73E_001917"
     tRNA            complement(5038..5109)
                     /locus_tag="ACL73E_001917"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5075..5077),aa:Gln,seq:ttg)
     gene            complement(5123..5195)
                     /locus_tag="ACL73E_001918"
     tRNA            complement(5123..5195)
                     /locus_tag="ACL73E_001918"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5160..5162),aa:His,seq:gtg)
     gene            complement(5210..5280)
                     /locus_tag="ACL73E_001919"
     tRNA            complement(5210..5280)
                     /locus_tag="ACL73E_001919"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5246..5248),aa:Trp,seq:cca)
     gene            complement(5285..5365)
                     /locus_tag="ACL73E_001920"
     tRNA            complement(5285..5365)
                     /locus_tag="ACL73E_001920"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5329..5331),aa:Tyr,seq:gta)
BASE COUNT         2063 a          807 c          947 g         1556 t
ORIGIN      
        1 aaaatattgt tgacaaatag aaaatactgt gttaaaatgt ctatataaca gagacagttg
       61 gaggtataag aatgagtcgt acttatataa atataagact tgcatacgaa accaagtatt
      121 ggttagaatg tatacaagaa gaggttcaaa aaaaattaga tgctttaatt aatgaacaag
      181 atatagagga gttagaatca atcatcacta ataagttaga aaaaaaagat tctctattgg
      241 gggctgtttc cataacaact tttttcaagg tatcttcttc aagcgtgatt gaaaaagcct
      301 ataacgagac aaaaaattac actacttcag aatggcgaga aattgcaagg caaatgaatt
      361 tggcaaaagt taagcaaaac atggaaattg ggacgttaac acctagatta tatttagata
      421 ataatattat ttcagaatta gagaagtatc aatttttatt caaaagtgat gatatgataa
      481 ggcaggtaag gatgagctat gttattaaaa tggtcgcatt tgcctactat aaaaaattgt
      541 ttgcatgatt tataagctcg ataataagag cttataaaaa tacaaccttt gtctgtgtta
      601 acgagacttt taaacttttt aatcggaagg agaatatttt gataggagcg tcacctatta
      661 tttatttgac aacattaaat aaaaactaat attaaaaaaa tataaaggag gagcagaaat
      721 gccaaaatta ttagagactg aaaaatacag tttagatagc attatagatg gagggaagct
      781 tagaatgatt tctaagtttt gcccagactt acatggcttg aggtacgaat tcaaaacatc
      841 agactcaatt actaaagaat attgtaaaaa aatacgtcaa gctttaagag attctgatcc
      901 agaaggaaag agtggaaaaa aatgtatgat gagatataca atagatattt taaatgtatg
      961 gaacacgcta tgtagaacac gagattttat aacggggagt ttaaaagcgg atgatgttat
     1021 agatgggaag acagggatat acttctttga tgttaatacg tctaatgtaa ttacggatga
     1081 tgttatagaa aatgttaaaa ttaatcacaa aagcttagta cgaaatgttg atgaagaaaa
     1141 tatagaaagt atttcaaaag aaattcctaa aggtactgat atgtattatt atgttttgta
     1201 tagattaggg ttgaatagga ttaagtataa ttatttagtc aaggctctgg caggcgcaat
     1261 acagaaggat taagaatata attatataat taagggggag ttttttctcc ccttatagag
     1321 atagtattat tcttttggta tttggggtat cgtttatcaa tctcatctta tagctaataa
     1381 aaatagtcta tgtttttagt gaaaaaaata ttattttaag gagtggtgat atgtatatac
     1441 ttgtcacaaa tgggaaaagc tacgtgactt tcccttggtt gcgtgaaata gcttgcagaa
     1501 attataaagg agaaactaag gtgtttacta caaaggaact ctataatttc ctatattaaa
     1561 cgctttaact atcacatttt taataccaag aaaagtaaat taaaatatat agcagtatta
     1621 gagaggcaaa aacgtaaagc atggcatagt catattttgc tattcagtgt tccctatatt
     1681 ccacataagc aattattaga actttggggg catggagcag tacggataaa taaagttgac
     1741 gttgacagca aagaaaatcg cggtcgatat gtcacaaagt attttgaaaa aggtattgga
     1801 caagaattgt tggaaaactt cggaaagcaa gcctattttt catcacgcaa cttgaaaaag
     1861 cctgatgaag ataaatttta cacttatgaa gattttaact atgatagttc agtcgtacta
     1921 tatgaaacgg aatacaactg ataacccgag gctttacagt ctatcagaac aagcgaattg
     1981 gtactatacc tgctactatt gctaccgaat tactcggttt tgatgttcaa aacagtaccc
     2041 tcaaggagta aaatatggca attagaaaag gtaaagacgg taattgggta gttgatatta
     2101 gcaacggttt tgacccaata acactaaagc aacgtagact tgtcagaaag ggatatatga
     2161 cgaaaaaaga agctattgaa gcagaacact acttacgaag tgtagagtta aaagaacgct
     2221 tctatggggc taaaataact atctccatac tatatgaact acttaaggaa gaagatagca
     2281 taaatcatcg aaaagcaagc tatatcaata cacaagataa taattacaac aaacacatca
     2341 aagattattt ttctatggtc gataatgtcg gaaaactaac ctatgaagac atctaccaat
     2401 ttagagaaca tcttaggcaa aaagtagcta aaaattctga taaaccgtta agcacaaata
     2461 ctattaacaa aatcatgatt ttactcaaaa aaatttttga tgttggtttg cgaaaaggct
     2521 attactcctc caatccagca aaattgataa aaaagttgcc aattgaaaaa acaaaaatgc
     2581 aattttggac agtcaaagaa tttcagaagt ttttgacact atttgaaccc gaagaataca
     2641 atatcaaact actctttact gttctattct ttacaggatt aagacttggg gaagctcttg
     2701 ctctaacatg gcaagacatc gacttttcaa gtaatacaat tcatatcacg aaatctgtct
     2761 atgttaataa aggagtaact catatcagca caacaaaaac taaagcagga acaagaagaa
     2821 ttgttatcaa taaaaaatta agccaagaat tacaagattg ggaaaagcga caaaaacatc
     2881 tattagagca atttaccaac aatagcctaa cattacaagt gtttcaaaat agtcctatca
     2941 caattacaaa aaatgctatt gaaaagcagt acaagaaaat cattgaacgt gatagtacac
     3001 taaaaaagat acgcatacac gattttaggc actcacacgc ttccctgctg attaaccaag
     3061 gggaagatta tctagttgta aaagagcgac taggacatgc ttctataaca accacgattg
     3121 atacctactc tcacttgtac ccaagtaagc aaaaggattt agctgataaa ctagatgatt
     3181 tactataaag taattgagtt ttataaatgg aaagtttata attaaatcat ggatacatca
     3241 caagtaataa aagcacatga agtagctaaa aaagcacact ttggacaaat tgatagagca
     3301 ggaattgact acattaaaca ccctgaaaca gtagctagtt ttgtcacaac tgatgaagag
     3361 aaagctgtcg cctatctaca tgatgtaatt gaagatacta cactaaccct actagaccta
     3421 aaaaaggaag gtttttcaaa aaacattata gaagcagtcg atatactcac aaagaaaaaa
     3481 ggacaagatt atcaatctta tctcaatcta gtaaagacaa atgaacttgc tagagttgta
     3541 aaattggcgg atttacggca taattcagat ttaaccagac taccattaat tactgaaaaa
     3601 gacttagaga gaaataagaa atacagttct gctattagat ttttaagaac aaagaaaaaa
     3661 agttagtaac taaactataa aaatttataa agagaaaaca aggcttataa actttgtctt
     3721 tattactatc ttggcggtca gtctcgaact ggcacatcct tgcagatact acaattttat
     3781 taaaataaat actatacaaa gtgaaatttt ttattgagaa acttttagac taggagtata
     3841 atgtatctaa aataactatt aggtggctgt tatatgaata atgttgttac tacactaatt
     3901 tctgttcaat ttagtcaaga gttaaattct ttattaaatg ctattgttga agaaaataat
     3961 acaacaaaga ctgactttat tagacaagct gttatagaga aaattgaaga tatgtatgat
     4021 attaaggtcg ctgatgaagc ttataaaaaa tgggttgaat gtggcaaaaa aactatctca
     4081 catgaagaaa tgatgagacg ctatggctaa aatatacgca atatctgata tacatggata
     4141 cttggatgaa ttcatagacg ctctcaataa agtaaattta aacgataaag ataatcgcct
     4201 atttttacta ggagattatc ttgataatgg acttcaatct tttcaagtca tttccaaaat
     4261 aatcgaactt gaggagattt atcctaatca aattattact cttctaggga accatgaaga
     4321 atggttttat gattggttga ttttagataa gcctactgct tcagcatttc cagaaacaat
     4381 aaaaagcttc ttctctccag aggaattgaa ctatattttt aaatcgaatg ctaacaactt
     4441 tgaaacaggt gttagaaatg aaattaaaaa taatatcaaa ttcaacccat ttataaactg
     4501 gtttaaaaag cgatataggg ataaacgcta ttatgaaact gatacccaaa tttttgttca
     4561 tgcaggcatt gatgaagaag caggaatgct ttggaaagaa ctaacgagtt caaagatatt
     4621 tacaaacaaa tttccaatta ccactggtag atttcataaa gctattattt cgggccatat
     4681 tgcttcttgg gaagtagcta aagatagaag atacctaggt aagatttact atgatagtaa
     4741 aagtcattac ttaattgatg gagatgtaac gaatagcaaa acaatacctg ttctttgcta
     4801 tgatacaatt acccaaaaat atcactttct ataactttta gtcatgtgct tttatatgaa
     4861 attagtaatt attagtaaca attccaagaa atttcttatg acataacaaa aagacaaggc
     4921 ttagaaacct tgtcttttca actataccgg cggccggggt cgaaccggca cgtccttgcg
     4981 gacactggat tttgagtcca gcgcgtctgc caattccgcc acgccggcaa atagtaactg
     5041 gggtagctgg attcgaacca acgcatgagg gagtcaaagt cccttgcctt accgcttggc
     5101 tataccccaa taatataaaa taggcgagtg atggggatcg aacccacgca tgccagagcc
     5161 acaatctggt gtgttaacca cttcaccaca cccgccataa ttctattaac acgggcagta
     5221 ggaattgaac ccacactgaa ggttttggag accttagttc tacctttaaa ctatgcccgt
     5281 aaaatggaag gggagggatt cgaacccccg aacccgaagg agcggattta cagtccgccg
     5341 cgtttagcct cttcgctacc cttccaaaat ata
//
LOCUS       DBERDS010000072         5220 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.072, whole genome shotgun sequence.
ACCESSION   DBERDS010000072 DBERDS010000000
VERSION     DBERDS010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.072"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(366..1094)
                     /locus_tag="ACL73E_001921"
     CDS             complement(366..1094)
                     /locus_tag="ACL73E_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGS0801819.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1252..2661
                     /locus_tag="ACL73E_001922"
     CDS             1252..2661
                     /locus_tag="ACL73E_001922"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS0801820.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2679..3974
                     /locus_tag="ACL73E_001923"
     CDS             2679..3974
                     /locus_tag="ACL73E_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGS0801821.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3979..4287
                     /locus_tag="ACL73E_001924"
     CDS             3979..4287
                     /locus_tag="ACL73E_001924"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGS0801822.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4284..4592
                     /locus_tag="ACL73E_001925"
     CDS             4284..4592
                     /locus_tag="ACL73E_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGS0801823.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1759 a          881 c          948 g         1632 t
ORIGIN      
        1 ataaattggg agattgaaat tcatttctag caatttttta gaagtcacag tctactattc
       61 taacctcagt atactatatg tgttacaaga aaagactcaa aaacttctcg tcagtgtaag
      121 aatgtttgaa acaccattta aaactaaata actataagaa gtagatcagg tgaacaattt
      181 cagtacctac tctataagct atacgaagat atttttcaac atgatggata aaacgatcac
      241 tcttttaaag ccatcttatt tagaaaagag aaaccattta agcatagatg ggaccttctt
      301 gccctgtttt aaatttttct taaactagag tctgtaaaag attggcttca ttttcacatt
      361 ttctcctagg aggaatgtcg taatgcaaaa gaattaaatt caaataaatc atagcgatga
      421 cgactaatcg agtactcaaa cggagttccg ttatccaaat aagccacttg ttctacttca
      481 aataccggtt ccgttggaag gagctgcaag taatgttgct cattttctga actagaagaa
      541 gctcgcaaga tttttgtagc actggcaata tgcaatccta actttccttc aatgtaattg
      601 taaatcgatt tttgtaaaat atcttcagta atacctggaa taacatcggt actcatataa
      661 gtttgttcca gaacataagg tttaccgtca ataatacgca gacggtaaat attataaact
      721 ggactctgca aagcgacctg tagtttttct gctaaaaatt catttgcaaa ttctaatttg
      781 aagtgaataa tcctcgagtc aattgtagaa tgagcatctt cagatatttt tgtcagtccc
      841 cggatatctc tttctggaac gattaatttt ctttttgagc tgccacgaga gagaacaaag
      901 gttccctgcc cacgttttct aaaaattaag ccctcagaaa ctaacaagtc taaagctttt
      961 ttgatcgtca ttcgactaca ggcaaactgt ttagctaatg tcatttcatc aggcaattgt
     1021 tcgttcatgg tatatttatt acaaagaatc ttttcacgaa tctcattgta aataaataaa
     1081 tattttgtac tcatttaatc tggttctctc tataatattc taatagtagt ataacaaagt
     1141 tcaagaaatg aggcaaacac aagatatgta tcaacaattt ttaaaaatgt ctagacaaat
     1201 tttaaaatta tgctatactt tatgtataga ataatagaaa ggaggttgag catgaaaaaa
     1261 aagttagtat ttcctaatct gttttggtgg ggagctgctt ctagcggacc tcagacagaa
     1321 ggtcaatatg gaaaagtaca tgaaaatgtg atggactact ggttcaaaac gcatccagaa
     1381 gattttttcg ataatgtcgg acctcttgta gccagtaact tttttcatac ttacaccgaa
     1441 gatttccact tgatgaagga aattggagtt aattctttcc gcacttccat ccaatggagt
     1501 cgactcatca agaatttaga gacaggtgag cctgatccaa aaggtattgc tttctacaat
     1561 gccatcattg aagaagctaa aaagaaccag atggatcttg tgatgaattt acatcatttt
     1621 gatttaccag tggaacttct tcaaaaatac ggtggttggg aaagcaaaca tgtagtggag
     1681 ttattcgtga agtttgccaa gactgctttc acatgctttg gagataaggt tcattactgg
     1741 acaactttca atgagccaat ggtcattcca gaagcaggat acttatatgc tttccattat
     1801 ccaaatctaa aaggaaaggg aaaagaggcc gtacaagtca tctataatct aaaccttgct
     1861 agtgcaaaag tgattcaact atatcgctca ttagaacttg atggaaagat tgggattatt
     1921 ttaaacttga cacctgctta tccaagaagt aattctccag aagacttaga agcaagtcga
     1981 tttacagatg acttctttaa caaagtcttc ttgaatccag ctgttaaagg aactttccca
     2041 gaaagattgg taaaacagct agagagagat ggcgtgttat ggagtcatac cgaaaaagag
     2101 cttcaactga tgaaatcaaa tacggttgat tttcttggag taaactacta ccatccaaaa
     2161 cgtgttcaag cacaagcaaa tcctgaggaa tatcagacgc cctggatgcc agaccaatac
     2221 ttcaaagagt atgaatggct ggagcgtcgc atgaatccat atcgtggttg ggaaattttt
     2281 ccgaaagcca tttatgatat tgctatgatt gtgaaggaag aatatggtaa tatcccatgg
     2341 tttatcagtg aaaacggaat gggtgttgaa aacgaagcac ggtttatcga tgaaaatgga
     2401 gttatcgatg acgtgtatcg tattgaattt tatgaagaac atttaagatg gctacataaa
     2461 gccattgaag agggaagtca ctgttttgga taccacgctt ggaccgcatt tgattgctgg
     2521 tcttggaata atgcatataa gaatcgttac ggatttatct ccgttgattt agaaacgcaa
     2581 aagagaacca tcaagagctc aggaagatgg tatcgcaaag taagtgacaa taacggtttt
     2641 gaagtagaaa ttgaggagta aagagaggag atattcatat gaaaaactca aaatttatag
     2701 accaatttgc cacctttgct ggtaaactag ggaaccaaat tcatttaaaa accctaagag
     2761 atgcattcgt aacagtaatg ccattatata ttttggcagg tttaatcgtt cttttgaaca
     2821 acacggtatt taagtggatt ttccaagggg atacattaac aagattccaa tattggggaa
     2881 taacaattgc aaacggtact ttaagtattt caggtatgat tattgctgta atggttggtt
     2941 atttcttagc taaaaacaga gatttcgaaa acccgttagc agcatcaatg ctatcattag
     3001 tttctttaat tgtgatgatg ccaaatacag tttctgtagt tcctgacgga gcaaaagatg
     3061 cggtaaacat ttcaggtgtt ctttcattca acaacacagg tacaggcgca atgttcgccg
     3121 gggttatcgt agcgattatt gcaacagaat tattcattga attatcaaac gttaaagctt
     3181 tacaaatgaa ccttggtgaa aatattccac cagctgttag tagatcattt agcgtattac
     3241 ttccagtcat gaccgtcatc tccttatttg gggttgtttc agcattatta ttcaatataa
     3301 ctggaatgaa cttaatctca atcattacaa tctttattca agaaccaatt cgtcatattg
     3361 gtacaagctt aatcggggtc attattattt actctttagg aaatatgtta tggctatttg
     3421 gtattcacca agcagttatt tacagtgcca tcctagaacc attactatta attaacatta
     3481 ctgaaaacat cactgcagca aataatggac aagccattcc acacatcatc aacctatcac
     3541 aaatacaaac attcgcttta atgggtggta gtggatctac attatgttta ttaatagcaa
     3601 cattcttagt gagtcgcaat gctgtctcta aaaacgtggc taaattatct tttggacctg
     3661 gtatcttcaa tatcaatgaa ccagtattat tcggttaccc aatcgtttat aacatttcat
     3721 tagctattcc atttatcaca gttccagtcc ttggtatttt aatcagctac ttagcaacag
     3781 ttacaggatt catgagtcct gcatttatac aagttccttg gactacacca gtattcttaa
     3841 atgcatggtt agcaacagca ggggacgtga gagcagttct agttcaattc atcatctttg
     3901 cacttggagt tcttctatac attccattta tcaaagttaa tgacaaagtt gttgaacaag
     3961 aaatggaagg ttaagattat gaaacaaatt ttattagtat gtaatgcggg aatgtcgaca
     4021 agtatgcttg ttaaaaaaat gcaacaaagt gcgactgaac gtgggattga aatctctatc
     4081 caagcaaaat caatgacaga agctaaaaag aatatccatg aagcagatgt cattctaatt
     4141 gggccacaaa ttcgttatga gttacttgct gtgaaagaaa ttgcaggaaa tatccctgta
     4201 gataccattg atatgcggga ttacggaatg atgaatggag caaaagttct ggaacaagca
     4261 cttgcatgga taggagaaat aagatgacag aagaaatgga atatatctgt tttcagctca
     4321 ttgccaatag tggagcagcc aaatcatcct ttattgaagc catccaacta gctaaggcag
     4381 gaaatttaaa agaagcgaaa attaaagttg aagaagcgga agactcctta gtagaagcgc
     4441 acaagattca ctctaatctc atacaaaaag aagctactgg agaaaaaata ggattctcct
     4501 tgctatttat gcatgcagaa gaccaaatgg cttcaacaga gattattcag ttgctatcta
     4561 aagaattcat cgatctctat caaaataaat aggaacactg tcattcccat ctgtctttat
     4621 taatgacgac tacattgtag gaacctccaa aagttggaca aaatgattga aaggattgga
     4681 tcctgcatta cacaagatcc aatccttttc ttttactcta gtttttataa tatgttgaat
     4741 ctagaatagt ccactgtagt ttctaaaaaa ttgctggaaa tggatgttaa gctccaattt
     4801 atttgtttat atcttatttc agtttactat actagcttat tattctagtg aaaaattgaa
     4861 tgagccacta tttatttaat atgtatgatg agggaatgac tcaaaaactt cttgtcgata
     4921 taagaatatc tgagatagta ttttaaaacg aaaggactat aaaagctcat ttccttcgca
     4981 cttattttat aaagatctat cattatactc tttagaaatc aaaaagcaac acaccttgtc
     5041 atcgttttat cgtaaatctg ttaatgaggg ggctagtctt atctgcaatc tcaaatcagt
     5101 gttttgagct gaatggcact cgttttctag tttgctcttt gattttaatt gggccttagt
     5161 aaatactact cttaaattaa actatagtga attgaaataa gatgtgaaca actctatcag
//
LOCUS       DBERDS010000073         4800 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.073, whole genome shotgun sequence.
ACCESSION   DBERDS010000073 DBERDS010000000
VERSION     DBERDS010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4800
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.073"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..1396
                     /locus_tag="ACL73E_001926"
     CDS             <1..1396
                     /locus_tag="ACL73E_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGS0801824.1"
                     /translation="PAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETA
                     AGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEA
                     LDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKY
                     TTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPS
                     TGHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNI
                     KFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNASDHVRKNKADQDS
                     KPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEI
                     PQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLTGLKSSLLLGTKDNNTISAEVDS
                     LLALLKKSQPAPIQ"
     gene            1606..4725
                     /gene="phtE"
                     /locus_tag="ACL73E_001927"
     CDS             1606..4725
                     /gene="phtE"
                     /locus_tag="ACL73E_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGS0801825.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1744 a          821 c          971 g         1264 t
ORIGIN      
        1 accagctcca agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg
       61 cgatggttat gtctttgagg agaatggagt ttctcgttat atcccagcca aggatctttc
      121 agcagaaaca gcagcaggca ttgatagcaa actggccaag caggaaagtt tatctcataa
      181 gctaggagct aagaaaactg acctcccatc tagtgatcga gaattttaca ataaggctta
      241 tgacttacta gcaagaattc accaagattt acttgataat aaaggtcgac aagttgattt
      301 tgaggctttg gataacctgt tggaacgact caaggatgtc tcaagtgata aagtcaagtt
      361 agtggatgat attcttgcct tcttagctcc gattcgtcat ccagaacgtt taggaaaacc
      421 aaatgcgcaa attacctaca ctgatgatga gattcaagta gccaagttgg caggcaagta
      481 cacaacagaa gacggttata tctttgatcc tcgtgatata accagtgatg agggggatgc
      541 ctatgtaact ccacatatga cccatagcca ctggattaaa aaagatagtt tgtctgaagc
      601 tgagagagcg gcagcccagg cttatgctaa agagaaaggt ttgacccctc cttcgacagg
      661 ccatcaggat tcaggaaata ctgaggcaaa aggagcagaa gctatctaca accgcgtgaa
      721 agcagctaag aaggtgccac ttgatcgtat gccttacaat cttcaatata ctgtagaagt
      781 caaaaacggt agtttaatca tacctcatta tgaccattac cataacatca aatttgagtg
      841 gtttgacgaa ggcctttatg aggcacctaa ggggtatagt cttgaggatc ttttggcgac
      901 tgtcaagtac tatgtcgaac atccaaacga acgtccgcat tcagataatg gttttggtaa
      961 cgctagcgac catgttcgta aaaataaggc agaccaagat agtaaacctg atgaagataa
     1021 gggacatgat gaagtaagtg agccaactca ccctgaatct gatgaaaaag agaatcacgc
     1081 tggtttaaat ccttcagcag ataatcttta taaaccaagc actgatacgg aagagacaga
     1141 ggaagaagct gaagatacta cagatgaggc tgaaattcct caagtagagc attctgttat
     1201 taacgctaag atagcagatg cggaggcctt gctagaaaaa gtaacagatc ctagtattag
     1261 acaaaatgct atggagacat tgactggtct aaaaagtagt cttcttctcg gaacgaaaga
     1321 taataacact atttcagcag aagtagatag tctcttggct ttgttaaaaa aaagtcaacc
     1381 ggctcctata cagtagtaaa atgaatggag catattttat ggagaagtaa cctttcgtgt
     1441 tacttctctt ttttagaaaa acgtaacaga aacttgacaa aagtaatttt aaatagtaaa
     1501 ctatttactg gttaattaaa tggttaaata accggtttag aaaactattt aataaagtaa
     1561 aagaagttga gaaaaaactt catcatttat tgaaatgagg gatttatgaa attcagtaaa
     1621 aaatatatag cagctggatc agctgttatc gtatccttga gtctatgtgc ctatgcacta
     1681 aaccagcatc gttcgcagga aaataaggac aataatcgtg tctcttatgt ggatggcagc
     1741 cagtcaagtc agaaaagtga aaacttgaca ccagaccagg ttagccagaa agaaggaatt
     1801 caggccgagc aaattgtaat caaaattaca gatcagggct atgtaacgtc acacggtgac
     1861 cactatcatt actataatgg gaaagttcct tatgatgccc tctttagtga agaactcttg
     1921 atgaaggatc caaactatca acttaaagac gctgatattg tcaatgaagt caagggtggt
     1981 tatatcatca aggtcgatgg aaaatattat gtctacctga aagatgcagc tcatgctgat
     2041 aatgttcgaa ctaaagatga aatcaatcgt caaaaacaag aacatgtcaa agataatgag
     2101 aaggttaact ctaatgttgc tgtagcaagg tctcagggac gatatacgac aaatgatggt
     2161 tatgtcttta atccagctga tattatcgaa gatacgggta atgcttatat cgttcctcat
     2221 ggaggtcact atcactacat tcccaaaagc gatttatctg ctagtgaatt agcagcagct
     2281 aaagcacatc tggctggaaa aaatatgcaa ccgagtcagt taagctattc ttcaacagct
     2341 agtgacaata acacgcaatc tgtagcaaaa ggatcaacta gcaagccagc aaataaatct
     2401 gaaaatctcc agagtctttt gaaggaactc tatgattcac ctagcgccca acgttacagt
     2461 gaatcagatg gcctggtctt tgaccctgct aagattatca gtcgtacacc aaatggagtt
     2521 gcgattccgc atggcgacca ttaccacttt attccttaca gcaagctttc tgccttagaa
     2581 gaaaagattg ccagaatggt gcctatcagt ggaactggtt ctacagtttc tacaaatgca
     2641 aaacctaatg aagtagtgtc tagtctaggc agtctttcaa gcaatccttc ttctttaacg
     2701 acaagtaagg agctctcttc agcatctgat ggttatattt ttaatccaaa agatatcgtt
     2761 gaagaaacgg ctacagctta tattgtaaga catggtgatc atttccatta cattccaaaa
     2821 tcaaatcaaa ttgggcaacc gactcttcca aacaatagtc tagcaacacc ttctccatct
     2881 cttccaatca atccaggaac ttcacatgag aaacatgaag aagatggata cggatttgat
     2941 gctaatcgta ttatcgctga agatgaatca ggttttgtca tgagtcacgg agaccacaat
     3001 cattatttct tcaagaagga cttgacagaa gagcaaatta aggctgcgca aaaacattta
     3061 gaggaagtta aaactagtca taatggatta gattctttgt catctcatga acaggattat
     3121 ccaagtaatg ccaaagaaat gaaagattta gataaaaaaa tcgaagaaaa aattgctggc
     3181 attatgaaac aatatggtgt caaacgtgaa agtattgtcg tgaataaaga aaaaaatgcg
     3241 attatttatc cgcatggaga tcaccatcat gcagatccga ttgatgaaca taaaccggtt
     3301 ggaattggtc attctcacag taactatgaa ctgtttaaac ccgaagaagg agttgctaaa
     3361 aaagaaggga ataaagttta tactggagaa gaattaacga atgttgttaa tttgttaaaa
     3421 aatagtacgt ttaataatca aaactttact ctagccaatg gtcaaaaacg cgtttctttt
     3481 agttttccgc ctgaattgga gaaaaaatta ggtatcaata tgctagtaaa attaataaca
     3541 ccagatggaa aagtattgga gaaagtatct ggtaaagtat ttggagaagg agtagggaat
     3601 attgcaaact ttgaattaga tcaaccttat ttaccaggac aaacatttaa gtatactatc
     3661 gcttcaaaag attatccaga agtaagttat gatggtacat ttacagttcc aacctcttta
     3721 gcttacaaaa tggccagtca aacgattttc tatcctttcc atgcagggga tacttattta
     3781 agagtgaacc ctcaatttgc agtgcctaaa ggaactgatg ctttagtcag agtgtttgat
     3841 gaatttcatg gaaatgctta tttagaaaat aactataaag ttggtgaaat caaattaccg
     3901 attccgaaat taaaccaagg aacaaccaga acggccggaa ataaaattcc tgtaaccttc
     3961 atggcaaatg cttatttgga caatcaatcg acttatattg tggaagtacc tatcttggaa
     4021 aaagaaaatc aaactgataa accaagtatt ctaccacaat ttaaaaggaa taaagcacaa
     4081 gaaaactcaa aacttgatga aaaggtagaa gaaccaaaga ctagtgagaa ggtagaaaaa
     4141 gaaaaacttt ctgaaactgg gaatagtact agtaattcaa cgttagaaga agttcctaca
     4201 gtggatcctg tacaagaaaa agtagcaaaa tttgctgaaa gttatgggat gaagctagaa
     4261 aatgtcttgt ttaatatgga cggaacaatt gaattatatt taccatcggg agaagtcatt
     4321 aaaaagaata tggcagattt tacaggagaa gcacctcaag gaaatggtga aaataaacca
     4381 tctgaaaatg gaaaagtatc tactggaaca gttgagaacc aaccaacaga aaataaacca
     4441 gcagattctt taccagaggc accaaacgaa aaacctgtaa aaccagaaaa ctcaacggat
     4501 aatggaatgt tgaatccaga agggaatgtg gggagtgacc ctatgttaga tccagcatta
     4561 gaggaagctc cagcagtaga tcctgtacaa gaaaaattag aaaaatttac agctagttac
     4621 ggattaggct tagatagtgt tatattcaat atggatggaa cgattgaatt aagattgcca
     4681 agtggagaag tgataaaaaa gaatttatct gatctcatag cgtaaggaat agcagtagaa
     4741 aaagtctgaa tcaaaaatga agttctctca aaagttagaa ataaaactct gactttggga
//
LOCUS       DBERDS010000074         4793 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.074, whole genome shotgun sequence.
ACCESSION   DBERDS010000074 DBERDS010000000
VERSION     DBERDS010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.074"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(176..1591)
                     /locus_tag="ACL73E_001928"
     CDS             complement(176..1591)
                     /locus_tag="ACL73E_001928"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGS0801826.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDITLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1604..3442)
                     /locus_tag="ACL73E_001929"
     CDS             complement(1604..3442)
                     /locus_tag="ACL73E_001929"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGS0801827.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAASFSALLAGITEPAVYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGIELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3460..4299)
                     /gene="licT"
                     /locus_tag="ACL73E_001930"
     CDS             complement(3460..4299)
                     /gene="licT"
                     /locus_tag="ACL73E_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGS0801828.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFVALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4600..>4793)
                     /locus_tag="ACL73E_001931"
     CDS             complement(4600..>4793)
                     /locus_tag="ACL73E_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HGS0801829.1"
                     /translation="SSQLKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEM
                     TILRLESASIVSELVAGLR"
BASE COUNT         1604 a          933 c          623 g         1633 t
ORIGIN      
        1 tatataacca atctatccta agttaactat ttataatcgg ctctctgtaa caaaattaaa
       61 ttaatccccc tataaaataa agaggtttag aatttgatgt cttccaaacc tctttatttc
      121 atatttaatg agatgctgcc ttaaccgtga taatatctaa tcatcaataa acaaactatt
      181 tgaataagga ttctccattt gattcaatca ctcctttata ccaagtaaag gacattttct
      241 tatatcgatt gaatgtgcca tttccatcat catttcgatc aacataaatg agaccgtacc
      301 ttttagaaag ttgtgcagtg gacatagaaa cacagtcaat acatccccaa gacgtatagc
      361 ccataatttc aacaccatcc tgtagagctt cagcaacttg caataaatgt tctttcatat
      421 actgaattct ataatcatct tggacggtta agttattaag ttcatctttt attagttgat
      481 ctttagcacc taatccattt tctactataa ataatgggat ttgataacgg tcataatatc
      541 tatttaaaat tatacgtagt ccaattggat caatttgcca tccccactct gaagactcta
      601 aataaggatt tactaaacca ccaataatat tcccttctcc tgaattatac tgtgttggaa
      661 gagcagattg agtcacactc atgtaatagc taaaggataa aaaatctaca gtataatttt
      721 ttaataactc tgcatcttca gctgcaaact ctatgttaat gtcattttcc ttaaaatatc
      781 tttttgcata attcggataa taacctctaa catgcacatc tgaaaataga taatttagat
      841 tctcatactc atgagtcgcc catacatctt ttggatttgg agtcattgga taagctggca
      901 tagctaatac catacacccc accttaaact ctgaattaat ctcacgagca atttttgtaa
      961 ccaaactcga ggcgactaat tcatgatgta tagcttgata taattcttgt ttcgaaagat
     1021 tctccttagg tatatctatt cctccactag taaacggtaa ttccaaaaca gagtttactt
     1081 cgttaaatgt aagccaatat ttaactttat ctttatacct ttctaaaact gttcgagcaa
     1141 atttttcata aaaatgaatc attctcctat caatccatcc atgatatttt cttgctaaat
     1201 ataatggagt ctcatagtgt gaaagagtta caagtggttc tatcccgtga gcatgtagtt
     1261 catcaaacaa ttcatcataa tatttcaacc cagcttcgtt aggttcttcc tcatctcctt
     1321 ttggaaaaat tctactccat gcaatagaag tacgaaaaac attaaagccc atttcagaaa
     1381 acaaggttat atcttcctta tatttatgat aaaaatcaat acctatcaat tttaagttat
     1441 cttctgtagg attttctgtt gcttctccta atccaccttt gggtaacaca tcctgaactg
     1501 ataagccctt accatcttca ttatatgctc cctctacttg attagctgca acagctccac
     1561 cccaaagaaa atcatctgga aaaatggtca taactttcct ccattataat attaccagta
     1621 attccttaga atgctcgatt gtctgattat taggtaatac taatacatct agaaaatcat
     1681 tggtattcgt tacaattact ggtgtaactg tttcgtagcc tttagtcttg attaaattca
     1741 agtccatttc aaaaatcaac tgatttttga aaactctgtc tccttcttct acatgactaa
     1801 taaaaccttg accttttagc tcaacagtat ctaatccaat atgaattagt aactcaatac
     1861 cctcatcact cttcaatcca attgcgtgct tagtcggaaa aatatttgta attttcccat
     1921 caaatggtgc ataaacctta ccttcacttg ggataatcgc tactccgtct ccaattagtt
     1981 tatctgaaaa tgttttatcc tggacatcgc ttaacggaat gatttctcct gatataggag
     2041 aaaatatcat ttttttattt gaaactccag ctttaacttc taaattgcta gaactctctt
     2101 cttcatcgat tccaaatata taagctaata caaaggtaat aacaaccgaa atgaccgcca
     2161 caattaaagc atttacaata tttgatggca catcagaata aataaattga ggcaacgcta
     2221 tcaaagatgg gacagcaaat agatacgctt taacactagt aagacctgca aataatcccg
     2281 ctaatccacc accaatcata gctgcataaa gcggtttttt atattttaaa gtcacaccat
     2341 atactgcagg ttcggtaatc cctgcaagta aggctgagaa acttgctgca aaagcaattt
     2401 gttttgtatt attattttta ctctttaatg caacagccat cgaagcagcc ccttgagcta
     2461 agtttgaccc taacattgct ggaagaatta atacgtctgg agtagcaata gatgccgcca
     2521 aaaaaatagg tgcaaaagcc caatgcattc cagtcataac aataaatggc ataatagcac
     2581 caagaatagc taatgtaagc catccagcta caccatacat ttgcccaact agatttgata
     2641 atccttcacc aacaattact ccaataggtc cgactacaac taaggcaata cagcttgata
     2701 ctaataatac tagcgtaggt tgcaaaaaac tcttagtaat agctggtgtt aatttagcaa
     2761 ttattttttc aatatatttc atcaaccaaa ccataataag aattggaacg actgatgaac
     2821 cataactagc tggtgtcaca ggtgcaccaa ataaactaag aggattccct gattgcacca
     2881 tttgaacaaa atttggatgg agaagtacac ctgctacaga catagctaat gtagatgtta
     2941 cttttaattt ttgtgatgca gaataagcta ataacagcgg taagaaataa tatggagcat
     3001 ccccaaaaaa tgtcaaaaaa gcaatagtct gagaatctga ttgcaatata ccaagcattg
     3061 gtaaaatgat taccaagact ttcaacatac ctccccctaa cattgctgga atgattggag
     3121 tcatggaacc agcgatatac tcaatgattc tttctaaaat attccctttg tgcccttgaa
     3181 caactgaatc ggattcaaaa ttgccaagtt taacgaattc tttataataa ttagctacat
     3241 cattaccaag tataatttga tattgtccat tctttttcat aatacctatt acacctggta
     3301 tcttcttcac atcatcatca ttgactaaat tttcatcttt taattctaat cttaaacgtg
     3361 ttacacaatg ggtaactcta ttgacatttt tttcacctcc aattacatcg aggatttttt
     3421 gtaccgtatc tttataactc atggtattct cctattctat taatctaaat tttttgttaa
     3481 gcgacgaata tgagccatca aataaactaa ttcactagaa gtcagcaaat aattgtactc
     3541 cgtttgtata aacattgcca cctgttcacc acattcatat tctctaggat atttattttt
     3601 cattaatgct aacaagtctt catcatcatc gtcacaataa gttgtatttt caaccaagcg
     3661 atgggcaaat aattttatat gagttatgaa tctataataa tcaatagaat cttggttaaa
     3721 ctcagtacaa tagaaatctt gaatgatttt ctcaattccc ataattattt cagtgatttt
     3781 atacgactct tgaaaattat tttctaaatt agcattaaca aaatgtagcg ctacgaatgc
     3841 agcttcgtca attggaagtt caatacctaa ctcttttttt attatttgta aagccctttt
     3901 cccaagctca aattcttctt tataatattt cgagatttcc cagcgtaggg gattcgaaat
     3961 aataactcct tctttataac gttctatact cgaagaaata tgatccgtta gatttatata
     4021 gataatctca tcaaaattat tacctaatgt tattttacct agattaatta ttttttcggt
     4081 gatgtacacc aactccaaag gaacgttaat aaacatctct gtaaaacggg tcatattatc
     4141 tctatttttg agaaaaaaac ttttctcaat atcaattgga tttactttat ctccaatttt
     4201 tcttccaaaa gctatgcccc ttccaaaaag aagaatatcg atatcttttt tactttgcgc
     4261 aattacggca ttgtggttta gtattcgttt tatgatcata aaatttccct tttaaaataa
     4321 aaggaaccta cttaaaaaac atcaagaaac ttcttctgat gtgattaaat aggttcctgc
     4381 tcacttgtat tagtgataac atccttttat ttcaattttt aatggtgaca tgaagcttaa
     4441 ataattaata actctgtaac cgtttttatt ttatgatatt tcaatctatt tgtcaagtac
     4501 ttataaaaat ttttttattt tgtgtgattc gaatgtgata atggcaacag tctcactaaa
     4561 gaaatgaaaa tcatacatag aaatttttaa aaattttctc tatcgtaaac ctgccactag
     4621 ttcagaaact atactagctg attccaaacg taatatggtc atctcatcta ccttccctaa
     4681 taatggcatt gcaccatacc aaacaatagt cttattcacc aaaagaatag gcgttactat
     4741 ttttgattga gtaaaagaca ctttaatttt ctggctcttc aactgtgaac tac
//
LOCUS       DBERDS010000075         4130 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.075, whole genome shotgun sequence.
ACCESSION   DBERDS010000075 DBERDS010000000
VERSION     DBERDS010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.075"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            67..312
                     /locus_tag="ACL73E_001932"
     CDS             67..312
                     /locus_tag="ACL73E_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801830.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFTKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            713..1705
                     /locus_tag="ACL73E_001933"
     CDS             713..1705
                     /locus_tag="ACL73E_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0801831.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="ACL73E_001934"
     CDS             1707..2525
                     /locus_tag="ACL73E_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801832.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="ACL73E_001935"
     CDS             2527..3312
                     /locus_tag="ACL73E_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGS0801833.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3351..3629
                     /locus_tag="ACL73E_001936"
                     /pseudo
     CDS             3351..3629
                     /locus_tag="ACL73E_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
     gene            3566..3811
                     /locus_tag="ACL73E_001937"
     CDS             3566..3811
                     /locus_tag="ACL73E_001937"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGS0801834.1"
                     /translation="MSRRKKAYQGRKIGSQLLATLESEAHKKVGYLQVKTVAEGSNKD
                     YDRTNDFYRGLGFKKLEIFLQLWNPQNPCQILIKKLE"
BASE COUNT         1155 a          696 c          891 g         1388 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattaatatc tgattataaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttacaaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaacgctt gcattctgtt ttttattgga ctataatagg
      601 ttggtataaa gccttctgta gtaataaaat gtagaaggtg tagaaagtaa ggatttagaa
      661 tatttgtagt taaaaataca atgttgctat tccttatgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccaga acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccag actcgctctt tcataagcgt atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcgaact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcatgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtcc
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagttg atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtgga ttttgtggtt ggtgttttgg gagtctttct ggctcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt cgctgaggtt ttgaaggatt
     3421 tgccagaatg gtttggaatc ccagaaagca cataagccta tataaaagga accacgacac
     3481 tgcaagtttg gaccgcctat caggagagtg atttgactgg atttgtaagc ttatcctatt
     3541 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3601 aattgggagc caattgcttg ctactttaga gagtgaagct cataaaaaag ttggttatct
     3661 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3721 tcgaggtctt ggctttaaaa agttagagat ttttcttcaa ctatggaatc cgcaaaatcc
     3781 ttgtcagatt ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgct
     3841 atactgtaag tgtaatcgcc gatttagctt agttggtaga gcaaggcact cgtaaagcct
     3901 aggttatagg tagataaacg actgaggatt tgaaaaaata gataggtaga agataaccgt
     3961 taagccttac tcttagcggt tatttatatt gtttaatagc gctaatattt tatcaattat
     4021 gcctgttttc gtgtttctgg tagttgttca agtttattgc taatattttt gatggtatga
     4081 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactctt
//
LOCUS       DBERDS010000076         4029 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.076, whole genome shotgun sequence.
ACCESSION   DBERDS010000076 DBERDS010000000
VERSION     DBERDS010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4029
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.076"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..799
                     /locus_tag="ACL73E_001938"
                     /pseudo
     CDS             1..799
                     /locus_tag="ACL73E_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            809..2424
                     /locus_tag="ACL73E_001939"
                     /pseudo
     CDS             809..2424
                     /locus_tag="ACL73E_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            2889..3112
                     /locus_tag="ACL73E_001940"
                     /pseudo
     CDS             2889..3112
                     /locus_tag="ACL73E_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816181.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3124..3874
                     /locus_tag="ACL73E_001941"
                     /pseudo
     CDS             3124..3874
                     /locus_tag="ACL73E_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
     gene            3887..>4029
                     /locus_tag="ACL73E_001942"
     CDS             3887..>4029
                     /locus_tag="ACL73E_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HGS0801835.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKDILP
                     SKN"
BASE COUNT         1454 a          450 c          736 g         1389 t
ORIGIN      
        1 aagaaataaa attatccatc aatttggcta taccaatcat agaattaagt taattttaag
       61 taatgaagat ttaggtgcaa ctaatgccag aaacataggt atcaaaaatt ctagaggtaa
      121 gtatatatca tttttagacg atgatgatga atatatgcca gatcgaattt taaagttgat
      181 ggcttgtttt aaaaagagta gaatgaagaa tttagcttta gtttatagtt atggaataat
      241 aatttatcca aatggtacac gagaagagga gaagaccgat tttgttggaa atcccttgtt
      301 tgttcaaatg gttcacaata tagcaggtac gtcattttgg ttgtgtaaaa aagaggtgct
      361 agaattaatt aatggttttg agaaaataga ttcacatcag gacggtgttg ttttattaaa
      421 actacttgct caaggatacc aaattgatat agtgcgagaa ttcttggtga attactacgc
      481 tcacagtaaa gaaaacggta tcactggagt gacacaaaaa aacaattaat gcagatgaag
      541 aatattataa ttactgtagg aaatatttta atttattgag tttcaacgag agaatattgg
      601 ttacaaagaa atattattct ttaaacataa agcggttact attaatagga gacaaatgca
      661 aggctttaaa agtaatcaag aaggcaagag aagaaaaaat ttttaacgaa tttctttttt
      721 gaaatatatg ttattatatc attttggttt tttctattgt atatatgaca actatgttca
      781 attaaaattt agaaagtgag aaactattgt gtatactatt ataaaatcaa atataaaaaa
      841 atttagttta ttaacgatat ttattgttgc tggtcaatta ttgctaattt atgcagcaac
      901 tattaatgct ctggtgttga atgaattaat tgcgatgaat ttagagcggt ttttgaaatt
      961 gtcaatctac caaatgattg tctggtgtgg gataatattc cttgactggg tagtgaaaaa
     1021 ttatcaggtt gaagtgatcc aagagtttaa tctagagatt cgaaatagag ttgccacaga
     1081 catctctaac tctacctatc aagaatttca tagtaaatca tcaggaacat atctttcgtg
     1141 gctaaataat gatgttcaga ctttaaatga tcaggctttt aaacaacttt ttttagtaat
     1201 aaaaggaatt tctggtacta tatttgcagt tgtgactctt aatcactatc attggtcatt
     1261 gactgtagcc accttgtttt cattaatgat tatgctactt gtaccaaaaa tctttgcatc
     1321 gaaaatgcga gaagttagtc taaatttaac taaccaaaat gaagcttttt taaaatctag
     1381 tgagactata ttgaatggat ttgatgtgtt agcgtccttg aatcttttat atgtattgcc
     1441 taagaaaatt aaagaagcag gaattttatt aaagatggtt atacaaagaa agacaactgt
     1501 agaaacgtta gcaggcgcta ttagcttctt tctcaatatt ttttttcaga tatctctcgt
     1561 ttttttaaca ggctatcttg caataaaagg aatagtgaaa attggtacta ttgaagcaat
     1621 aggagcacta acaggtgtta tttttacagc gctaggtgaa ttaggaggtc aattatcctc
     1681 tattattggt acgaagccta tttttttaaa attgtattca attaatccaa ttgagtcaaa
     1741 taaaatgaat gatatcgaac caaatgaggt gaatagagat tttccgttat atgaagcaaa
     1801 aaatatttgc tataagtatg gagataaaga aatattaaaa aacttaaatt tttgttttca
     1861 acgtaatgaa aagtatttaa ttttaggtga aagtggaagc gggaaatcta cattattaaa
     1921 attattgaat ggctttttga gagattatag tggagaattg cgattctgcg gggatgatat
     1981 aaaaaaacct cctatttaaa tatggtttcg aatgttctat atgtagatca aaaagcttat
     2041 ttgtttgaag gtacgattag agataatatt ttattggaag aaaattatac tgatgaagaa
     2101 atactacagt ctttagagca agttggtttg agtgtaaaag attttcctaa taacatttta
     2161 gattattatg ttggtgatga tgggagatta ctgtcaggag ggcagaaaca aaaaattact
     2221 ttagctagag ggctaattag aaataagaaa atagtattaa ttgacgaggg aacttctgct
     2281 atcgatagga gaacttcgtt agcgattgaa cgtaagatat tagatagaga ggatttgact
     2341 gtcattattg ttacccatgc tccgcatccg gaacttaaac aatattttac taagatatat
     2401 caatttccaa aggattttat ttaagaatat aggggaggga aacatgagat tctattgtga
     2461 agcttatgag gtaattactg aagagaaaaa agtatcattt ttttatgtag atgagaaacc
     2521 cttaaggtat ctgttatttg actatatatt tctactagtt ctagctaaaa aaaaatatcc
     2581 caatcttatg aactgcaccc caaaagttag atttattctg tctaactttt ggggtgcagt
     2641 tcattttgca tagttttggc attcatccta gatatccata taaaatgtct gagattgttg
     2701 aaatgtctaa aaaaatatca gatctaaacg ataaaaaaga atttcacaaa aagaactgtg
     2761 agttgaggtt tcaagatagt gttcttgata acataaatag tgtcccgggt acaactcatt
     2821 tatttagttg tttaaatatt caaacattag taaaaattat tttatatatt tttcgataca
     2881 acagttgtat gaaaatattt aattttagag ataaagagct tatctttttt aataagattg
     2941 taaatgggct gatacaaaat attgaggaga attagaggat gatattgaaa ggatattgaa
     3001 atatttatat atatgtttat ttaacgaaat attcattatt aagaataagg tgaatttttt
     3061 tgatgatgtg gaatttaatc agacacttag tgagttttta gataaattgt agagggaatg
     3121 gttatgagta acaatactaa gtatatcttt ttatctccac atttagatga cgcaattttt
     3181 tcctgtggtg attatatttc aaaattaact tcagaaggag aaattgtact tgttattact
     3241 atattttctg gttacccttt gagccaacag ctacagccct ctgctaagca atttcataag
     3301 ttgtgtaacc ttgggaaata tccgattgaa gaaaggaaga aagaagacag gttagcttgt
     3361 gaacgtctac aatgtgattt tagacactta tcgtactatg aatgtctcta taggaaagat
     3421 agaaatggca attttctata ccgtcatatc tatagtgaat taaaaaatga ggacacatta
     3481 aagaatgata tcataaaaga gctgttaatg catttagacg acaaatgtgt cgtatattgt
     3541 ccgctttcac ttggtgacca tgttgatcat gtttttgtga atagtattgg aagggcgctt
     3601 gaatttatgc gttataaagt aatatattat gaggacttcc aatatgtaag tgatagtagt
     3661 atggttggtt atatgggaaa aactaaagaa ttaaaaatgt atcaagagga acttgataaa
     3721 aaaacattat attgatagaa tatcatcaat atcgtgctat aaatctcaga ttttgataat
     3781 ctggaaatca gttgaaaaac ttttaaacaa tattaaagag ttgtatttaa ggaatggggc
     3841 agcttattct attagatttt ggattaagaa ataaggaagt agttttatga atatagcagt
     3901 aattggtttg gggcatgttg ggctggccta cgcgttacta tttgcatcta aatataaagt
     3961 tgttgcatat gatatagatt ctgtaaaaat aaataattta aaaaaggaca ttcttccatc
     4021 taaaaatga
//
LOCUS       DBERDS010000077         3627 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.077, whole genome shotgun sequence.
ACCESSION   DBERDS010000077 DBERDS010000000
VERSION     DBERDS010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.077"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            89..1168
                     /locus_tag="ACL73E_001943"
     CDS             89..1168
                     /locus_tag="ACL73E_001943"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801836.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSEIERVYANLWTVA"
     gene            1113..2090
                     /locus_tag="ACL73E_001944"
     CDS             1113..2090
                     /locus_tag="ACL73E_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000948440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0801837.1"
                     /translation="MSFILKLRGFTLTYGQWRKEFQSRFFPVHYYGLNFNQGIAFSDL
                     AILWSYQQLAKKVKNFKFDDYYEIRTQVINEAVNNFKKSSLSGLFDGKIGTIWLIYEF
                     GEIDRAVELFTTHFIEIFENSQNKNLYSGQVSIDFSFKSPFRVLLTGTSGSGKTTILN
                     LINGSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQII
                     EVLKKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISAN
                     LDNDNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            2105..2845
                     /locus_tag="ACL73E_001945"
     CDS             2105..2845
                     /locus_tag="ACL73E_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGS0801838.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            2848..>3627
                     /locus_tag="ACL73E_001946"
     CDS             2848..>3627
                     /locus_tag="ACL73E_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGS0801839.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNN"
BASE COUNT         1255 a          458 c          691 g         1223 t
ORIGIN      
        1 gaatccaaag gattctccct ttttatttaa ataagtctgt ctagctatag atatattaag
       61 tttgataaaa tttcttggag attttgttat ggattataat ttcaatttgg agcatccttt
      121 ctttttcact aataatgatt atagtacaga tactagcata aagtaccaag taagtctgcc
      181 ttttaattgg cacgaagtaa tgaataatga tgagtgggtt tatcaatacc ctattggaaa
      241 atttgttgaa agacaagggt ggaaaataca cattagttca gagtataaca gttcacatga
      301 attgttacaa gatgtagcaa aaatttgcca tgaaatgcga attccattta aacatcttag
      361 tacagaagac aaatttatca tgcgaaacgg gaaattggtt agtcgaggat tttctggtaa
      421 atttattaca tgttatccaa atcaaaatga attagagtcg gttttgcaaa ggttagaaag
      481 tgccttaaag caatataatg ggccatatat tttaagcgat aaacgttggg atgaagcacc
      541 aatatatctg aggtatggtg tgtttaggcc gtcaagggat gatgaaaaga aggttgctat
      601 tgatgaatta attgttggcg atgaagttgt taaagatgaa cgtttaccag tatttaaaat
      661 tccaaaaggt atagtgcccc ctgacttttt gaataaatgg cttgacaaga aagataaaaa
      721 acagggagac tttcccttta ttatagataa tgcaattaga ttttcaaaca gtggtgggat
      781 atataatgct aggctaaaag aagatgggaa aaaaataatt ttaaaagagg ctagaccgta
      841 tacaggtcta ggatttgatg gtacttattc ttcagagaaa ttagcttcgg agtgcaaagc
      901 actaaaaatt ctaaatgaat ggagtgagac gcctaaaata tactggcacg gtaagatctg
      961 ggagcacacc ttcttaggaa ttgaacatat gaagggcgtt ccactaaata gatgggttac
     1021 caataatttt cctttatatg aagttgttga taagaccaaa gattatctat tgagagtttc
     1081 aaagatagta gaaaaactca tcgatttaac gaataagttt cattctgaaa ttgagagggt
     1141 ttacgctaac ttatggacag tggcgtaaag aatttcaatc aagattcttc ccagttcatt
     1201 attatggtct gaattttaat caaggaattg cgttttcaga tttagctatc ctttggagtt
     1261 atcaacaact agctaagaaa gtaaaaaatt tcaagtttga tgactattat gagattcgaa
     1321 cacaggttat taatgaggca gtaaataatt ttaagaaatc gtccctttct ggtctttttg
     1381 atggtaaaat tggtacaatc tggctcattt atgaatttgg ggagatagat cgggcagttg
     1441 aactttttac aactcatttt atagagatat ttgagaattc acaaaataaa aatttatata
     1501 gtgggcaggt aagtattgac ttctcattta agtcaccatt tagggtatta ttaacaggaa
     1561 cttctggcag tgggaaaaca acgattttaa atttaattaa tggttcttta aagccacaaa
     1621 aaggttatgt aaatttgtta tcacatggga aaaagagttc agattcaata ccaacagttg
     1681 atcagacacc atatattttt gacactacta ttcgtgagaa cgtaacttta tttcaaaatg
     1741 aatatttttc agatgatcag ataattgagg tgttaaaaaa ggtaaatcta tatgaagaat
     1801 tagaaaagat agatatacta aattatcaat gtggtgaaaa tggtagtaat ttgtctggag
     1861 gtcaaaaaca aaaaatagct ttagctagag ctctgattag aaataataaa gtgtacttat
     1921 ttgacgaaat atcagctaat ttagataatg ataattcaaa ttccatacat gatattctgt
     1981 tcaatttagg tatttcattt attgaagttt cacatcatta tgacttaaat gacaagagat
     2041 acactgatat atataaattg gaaaatggaa cacttttcaa aattaagtga ttggaggcaa
     2101 gaatatggat aaagattata tattaaaagt gaaagggctg tatcatcaat ttttactagg
     2161 aaataataaa acgttgcaag tgctgaaaaa tgtttctctt tctgcttcga gaggagaatt
     2221 tataagtatt ctaggaatta gtggttctgg aaagtcaact ttattaaaat gtatttctag
     2281 tttgcttgaa ccaacaagtg gggaagtaat tttaaatgga atcaacccct ataaaatcag
     2341 aaatgcaaaa ttgtcaagta taagacgtaa cgaagtatct tttatatttc aagcatacaa
     2401 tttaatacct tccctgccgg taatagaaaa tatagcactt cctttgcgat tatcacaaaa
     2461 aaaattaact attaaaaatg tagaaaactt actcaaaaga atgaagttta atgctggctt
     2521 aaacgatttt gttggaactc tgtctggtgg agaacaacag aaggttgcta tagctagagc
     2581 ggttattgct gatagtgata taatatttgc tgatgagcca actggggctt tagacagcgt
     2641 ttctcgtgaa gtaatttttg aattattgag agagttagta ggggcgggta agtgtgtaat
     2701 tatggtaacg cacgatatag aattggcctc gaaaactgat cgtgcattaa tattgaaaga
     2761 tggaaaaatt ttcaaagaac ttcatagacc tagcggggaa gagttgtata aaatcttaga
     2821 ggtacaatca actacggagg aatagagatg ctcagattag tttactatca atttttacat
     2881 aataagaaac aatggttagg cgtttcacca gtaatttttg tttcgagttt agttatggga
     2941 ttggctgtta atggggtaat taatgttgag aataattcgc aagtatttgt cggacttcca
     3001 gatcctaaac caatttttat gtttccgata gtattcggag gagtaacatt attctttgtg
     3061 ctctctaaca taataaatat gttggttgaa atttttagag atgattacga acttttggag
     3121 gtgttgggag caagtcgcct tcaactatca tttcttgtgg ggggacagat ttttatcatt
     3181 tcctcgatta ttagttttat tgcatatcta tgctctatat ttgttacgtc aaattattat
     3241 tattttttac aatacttttt cggggaaaat atattacctg atatccaatt tcaaacgagt
     3301 gctgttggat gtatcattac agtagtgttg atttcatttt tagcctttct aagtggttgc
     3361 ttttatacgt tcaagaagat tagaaatagg aagagttcta aaataaggca tgttctttca
     3421 atagtaaaaa gaatactgct attggctggt tttagtgtta tctggttgct ttctttgcaa
     3481 caaattttcc aagatagcac aattttagcg aaggcccaga taatattcaa tattgtaatc
     3541 ttagatattg tgattattta tcaattatct ccttttatac agtcatgttt tatcaaacta
     3601 ctttctataa ttatatttag aaataat
//
LOCUS       DBERDS010000078         3414 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.078, whole genome shotgun sequence.
ACCESSION   DBERDS010000078 DBERDS010000000
VERSION     DBERDS010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.078"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(155..409)
                     /locus_tag="ACL73E_001947"
     CDS             complement(155..409)
                     /locus_tag="ACL73E_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGS0801840.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(429..2270)
                     /gene="typA"
                     /locus_tag="ACL73E_001948"
     CDS             complement(429..2270)
                     /gene="typA"
                     /locus_tag="ACL73E_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGS0801841.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDSTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            2432..3157
                     /locus_tag="ACL73E_001949"
     CDS             2432..3157
                     /locus_tag="ACL73E_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGS0801842.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(3197..>3414)
                     /locus_tag="ACL73E_001950"
     CDS             complement(3197..>3414)
                     /locus_tag="ACL73E_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801843.1"
                     /translation="KKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDY
                     KIEKILNILGIVISVVNWIVAIALIFR"
BASE COUNT         1026 a          752 c          637 g          999 t
ORIGIN      
        1 accagtacta accaaatata aaatagatgc cattaaagaa ttttattcaa gtttttccca
       61 ttcatattat ccaaacaaaa gagatggtga taactcaaaa ataaattgca atcttgtaaa
      121 attcctagca aaaaagagag ccaaaactct ctttttatct tcttttactt tttttgactg
      181 gcatgagtgt gatgtctcta acactaaagt aagctaggat caacatggct attgctagga
      241 atatttctgt tggtaattga aaaattttca gaaaagatag aaccaataaa atcaagagtg
      301 ccactaaaat acataccata gcgacgatat tgacagtccc tttaatgctt tctggtgtcg
      361 caaatacata gagtaggagc agtaaaattc ctaggactaa atagaccatc tttctctctt
      421 tctagctctt attcagctga ttttttcttc ttgttagctt tctcacgctc tgctttgtta
      481 aggatttgtt tacgcaaacg gatagactca ggcgttactt ccatgtactc atcgtcgttc
      541 aagaactcaa gagactcttc aagtgtcaag atacgaggcg tcttgataac agctgtttgg
      601 tccttagtag ctgaacgaac gttggtcatt tgttttgcct tcgtgatgtt aactgtcaag
      661 tcattttcac gagagttttc accgatgatc attccttcat aaacctcagt acctgggttg
      721 acaaagatcg taccacgttc ttcgatagac atgattgagt aagttgtagc cttaccagca
      781 tcgatagaaa caagggcacc acggtgacgt ccaccaattt cccctggaat caatggcaag
      841 tattggtcga aggtatggtt catgataccg taaccacgag tcattgacaa gaactcagtt
      901 gagtatccaa tcaaaccacg cgctggaaca aggaagacca aacgagtttg accattacca
      961 gttgaaatca tatccaacat ttcaccttta cgttcagaaa ggctttggat aacagaccct
     1021 tggtattctt ctggagtgtc gatttgtaca cgttcaaatg gttcacattt aacaccgtcg
     1081 atttctttta cgataacttc tggacgagat acttgaagtt catagccctc acgacgcatt
     1141 gtttcgataa ggattgacaa gtgcaattct ccacgtcctg aaacagtcca tttatctggt
     1201 gaatcagttg agtcaacacg aagggaaacg tctgtttgca attctgcctg caagcgttct
     1261 tccaccttac gagaagttac ccatttacct tctttaccag caaatggtga gttgttgacc
     1321 aagaaagtca tttgaagagt tggctcatcg atgtgtagga ttggaagagc ttctactgca
     1381 tctgtcggag tgatggtttc accgacaaag atgtcttcca tacctgaaac ggcaatcaag
     1441 tcacccgctt tggcttcttg gatttcacga cgttccaaac caaagaaacc gaagagtttt
     1501 gtaacacgga agtttttagt tgtaccgtca agtttagaaa gggtaacttg gtccccaacc
     1561 ttaactgtac cacggaagac acgaccgata ccgatacgtc caacgaagtc attgtagtcc
     1621 aaaagtgaca cttggaactg caaaggctca tctgagttat ctactggagc tgggatatgg
     1681 tcgataatcg tgtcaaagat tggtgccata gtcgcttctt ggtcagctgg atcatctgac
     1741 aatgaagaag ttccgttgat cgctgaagca taaaccactg ggaaatcaag ctggtcgtca
     1801 tctgcaccaa gctcgatgaa aagttccaag acttcatcca ctacttctgc tggacgagct
     1861 gatggcttat cgattttgtt aacaaccacg attgggacaa ggtcttgttc caaggctttt
     1921 ttcaatacga aacgagtttg tggcatggtt ccttcatagg catctacgac caagacaaca
     1981 ccgtcaacca ttttcatgat acgctcaact tctccaccaa agtccgcgtg tcctggtgtg
     2041 tccataatat tgatacgagt tccgttgtaa gcaacggcag tatttttagc aaggatggta
     2101 attccacgct ctttttcgat atcgtttgag tccatagcac gctctgccaa ttcagtccgt
     2161 gcatcaagcg tttctgattg tttcaataat tcgtcaacca gggttgtttt accgtggtca
     2221 acgtgggcga taatcgcaat gttacggata tcttctctta attttgtcat gatttcctct
     2281 ataatattca aaatttattt tctaactgaa cgattatacc ataatttcaa gtaaataaca
     2341 taactcaagc aagtgtaaat gttttcactc cgcttttctt ttcacgtcaa gccttttcaa
     2401 agcaagcgac ttatgataag ataggcacag tatgcgttta gataatttat tagcccaaga
     2461 aaaagttagc cgaaaggcca tgaagcaagc actcctcaga ggggaaattc tagtcgatgg
     2521 ttgcccagcc cgctccctag ctcaaaatat cgatacagga ctacaagaac tcctttttca
     2581 ggatcgaatc attcaaggct atgaacacac ctatcttatg cttcataaac ctgctggtgt
     2641 cgttacagcc aacaaagaca aggaacttcc gaccgtcatg gacctgcttc catctgacat
     2701 ccagtctgac aagctctatg ccgttggccg actggaccga gatacaacgg gactcctcct
     2761 cttgaccgat aacggtccct tgggctttca gctcctccat ccccaatatc atgtcgataa
     2821 gacttaccaa gtccaggtta atggacttct aacacctgac catatccaag cctttcaaaa
     2881 gggaattgtc tttttagatg gtactgtctg taaacccgca aaactagaga ttctatctgc
     2941 aagtccctcc ctcagtcaag cctctatcac catttcagaa ggaaaatttc atcaaatcaa
     3001 gaaaatgttc ctctcggttg gtgttaaggt gactagcctc aaaagaatcc aatttgggga
     3061 cttcacattg aacccagatt tagcagaagg taactaccgc cctttgaacc aaaaagagtt
     3121 acaaatcatt aaaaactatt tagagatgag tcgataaaac aaaaaaagct ttaaaactaa
     3181 agcttttttc ttttatttac cgaaaaatta aggcgattgc tacaatccag ttaactacag
     3241 aaatcacaat tcctaagata ttaagaatct tttctatttt atagtctaat tgtgactctt
     3301 tttggtatga aatagccaag accaatccta tgatacccaa aatcaggcct acaattggaa
     3361 ataacaaacc aagaataatc gacaagatac ccacaaaaag tggatttttc ttct
//
LOCUS       DBERDS010000079         3209 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.079, whole genome shotgun sequence.
ACCESSION   DBERDS010000079 DBERDS010000000
VERSION     DBERDS010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.079"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..170
                     /locus_tag="ACL73E_001951"
     CDS             <1..170
                     /locus_tag="ACL73E_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGS0801844.1"
                     /translation="EYENRTVSFAISSKGENISYRVDHRILFDNISFDTSSSGVTLIT
                     GKNGTGKSTLL"
     gene            complement(292..458)
                     /locus_tag="ACL73E_001952"
                     /pseudo
     CDS             complement(292..458)
                     /locus_tag="ACL73E_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(536..1846)
                     /locus_tag="ACL73E_001953"
     CDS             complement(536..1846)
                     /locus_tag="ACL73E_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGS0801845.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2083..2955
                     /gene="nadC"
                     /locus_tag="ACL73E_001954"
     CDS             2083..2955
                     /gene="nadC"
                     /locus_tag="ACL73E_001954"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGS0801846.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3086..>3209
                     /locus_tag="ACL73E_001955"
     CDS             3086..>3209
                     /locus_tag="ACL73E_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGS0801847.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKL"
BASE COUNT          988 a          541 c          723 g          957 t
ORIGIN      
        1 aagagtatga aaacagaact gtttcttttg ctattagttc aaaaggagaa aatatttcgt
       61 atagggtgga tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg
      121 tgacattaat tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa
      181 ctagaatagt acacatctac ttctaaaata ttgttagaaa tcgatttgac tatcctgatc
      241 tatttgtcct gttcttattt catttcacta catctcaaat tgagtatgac gaagtgcgct
      301 cccatgtcct gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag
      361 actattggga tgaattttta aagttgaact aatcattttt acaggatgag gtttacagca
      421 gagagtttga aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac
      481 ttaattttgt gtctacttta ttataccaag tccaccctta agttagataa taaatctaac
      541 ttaaggaagc tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatgg
      601 ggacacccag aataatttgc tttttgaagg caaggccacg ttcctctata ttgggaagtg
      661 agagttgaat gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa
      721 taacggtggc tgttgtgagt aagtgaatat caatctgagg attttgagca ctgatgatag
      781 caatgatggg aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca
      841 ctccggctat cacacaaaag aacagaggta accagaaatg aggaatggat gttgtcatga
      901 ggtgccctat cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc
      961 cgcagagcat gataattgta gcccagggaa ctttagccaa aatggcttct tgcttcccta
     1021 atttgagcct taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt
     1081 tttgataagt agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc
     1141 aaaccaaaac catgctgctg atcatgagca aggtggtttg tctttgaacc ttgctgagga
     1201 gtggtggttg gtcaatagtc aaggatgagt ttgttcttcc cttactatag tgactgtaac
     1261 aggataataa aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc
     1321 caagtgaaaa agcttgctct tcccatccca tttgcttaaa caggccttga aagacaatgc
     1381 ctgagctact ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc
     1441 caatcaaagg gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg
     1501 ccatagtagt gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa
     1561 tcatgtagag ggcgttaggg taggtgcgtg tgcggtagag aatgtgttga gccaaaacat
     1621 caagagtacc gttagttatt gcaaagttat aaaagagaga gacgctaaaa atggtaaaaa
     1681 agagtgaggt tggccaaaaa tgaagaagtt ctttggggct taatcccatg agagtggttg
     1741 cgatgaggta agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa
     1801 ttccaatggc tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc
     1861 agttagaata tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt
     1921 ggtacttgac tattatacac aaaaaaaata caattgtctt gacaattgta ttgacaattg
     1981 ttagaattaa aaatgaggta ttcaggcttg tgatttccta tggaagttaa tagtgattgc
     2041 ctctaatgct tacaagtgat attaaaaata gaggacctag tgatgtcaat catttcaact
     2101 gatttaaccc cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcat
     2161 tccgaagatt acagtaccaa tgccattttt gatcatcatg gccaagccaa ggtgtcgctt
     2221 tttgccaagg aagctggtgt tttagcgggg ctaaccgttt ttcaaagggt ttttacccta
     2281 tttgatgccg aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact
     2341 agtggcgatt tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc
     2401 gttgccttga attttttaca acatttatca gggattgctt cgatgacagc tgcttatgta
     2461 gaagccttag gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta
     2521 cgtctttttg agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta
     2581 tcagatgcta tcctgctaaa agacaatcac attgcggcag taggtagtgt tcaaaaggca
     2641 attgctcaag cgcgtgccta tgcccctttt gtgaaaatgg tcgaggtgga agtggaaagc
     2701 cttgctgctg ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg
     2761 tcattggaac agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt
     2821 tctggaaata ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc
     2881 tccagtggta gtttaaccca tagtgctaag agtcttgatt tttccatgaa ggggttaacc
     2941 taccttgatg tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa
     3001 cgagttttat gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata
     3061 gtacacaatg tggtataatc tttttatggc atattcaata gattttcgta aaaaagttct
     3121 ctcttattgt gagcgaacag gtagtataac agaagcatca cacgttttcc aaatctcacg
     3181 taataccatt tatggctggt taaagctaa
//
LOCUS       DBERDS010000080         3081 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.080, whole genome shotgun sequence.
ACCESSION   DBERDS010000080 DBERDS010000000
VERSION     DBERDS010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.080"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(163..633)
                     /locus_tag="ACL73E_001956"
     CDS             complement(163..633)
                     /locus_tag="ACL73E_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGS0801848.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(650..2923)
                     /locus_tag="ACL73E_001957"
     CDS             complement(650..2923)
                     /locus_tag="ACL73E_001957"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGS0801849.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT          903 a          552 c          690 g          936 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg cggattgaag agattttcga agagtataaa
       61 tcttcctagg atagagcaaa acgcatagta tcaagggttt tctgatgtta aagactttct
      121 accaggtttt tttaaagcat aattgttagt tgtagtcatt tattattctt caaagaaaaa
      181 tggtggggcg aattttttca gttcttcaaa gcacttttga gcagtatctg catcttcaca
      241 gatgataaga cagacatcat taccacaaag ggtagcgata gcgtcaggga agctcaaagt
      301 atcaatgata gaaccaaagg attgagccag tccaggaagg gtttttagta ggacttggtg
      361 ttgaactggg cgcatccaga caagggcgtc ttccatgtag agttcgagac gtttttccca
      421 ttttgagatg gaaccattgt taagaacata ataagcgcta tcttcttcgc ggacttttga
      481 taggttcata tttttgatgt cgcgtgagag ggttgcctgg gttacttgaa tgtcgttctc
      541 agcaagaagg gcttgcaact cagcctgtgt atgaatcttg ttttttgtga taagagcgcg
      601 tataagttgg tggcggtgtt ctgatttatt cataataatg taactccttt tagcaaggta
      661 aggtaagcat ggactgagcg aggtcgacag tcaagtggta gtctgtattg tcacggatgg
      721 tgatttcaaa gtcagtagta tagaggacta aacggagagt gtctccttct tttagcttgt
      781 aaatagttgg ctgcagttca aattgaacgt ccatccattc atctgcagta atatcctcta
      841 ctaacagtaa atcatttcta ttttgtaaat taaggtaacc ttttgtcacg actcgttgtg
      901 cctctggtct aaatggcaat tcacagagat tttccaacat gtgatagcga ccgttatcaa
      961 tggttctagc acttaaaata gctggataag gttgtaggta tttcttttgc ccaaattcta
     1021 gcagttgggc agataagagc cccttgtttg tactggattt gatacgaaga ttgagctgag
     1081 cgcgaccgtt taggtggaga tctttagtca caggaaggtt aatagtaatc tgattggctt
     1141 tcccttgata gagctctgta ttgaaggttt ggtatgtctt accatagcgc tcaaaatcct
     1201 tatctgggta ctggttttga atagcttgct cttcttgacc aagtgagaag gtttcacagt
     1261 tttcttgccc accgaagtta tcaagtgata accaagtctg tggagctgta ttgtcctgcc
     1321 agataacagt aggaagttga aagtctgttt cctgtcctag taatttcttg gtcaataagg
     1381 catttatgga ctcacggaag tcaattgatt gccaattgtt catgtaaaca tgagcaccat
     1441 tatggaaaaa gagatgcttg tgtatatgag taggaagagc atggaacatc tggtaaacat
     1501 gaagtggttt gacattccaa tcctgagaac catgagtaaa gacaacctct gcctttactt
     1561 tatgggcatt gagcagataa ttgcggtcat gccaaaactg attgtagtcc ccagtttttc
     1621 ggtctagctg agctttcact ttttctaagt cagcttggtg agcttcattg ccacggatat
     1681 agtcgccagc taagagatta cgagaatagg ttaactcagc aagggagtca aagtcctcac
     1741 ctggataacc acctgggcta gtcaccagac cgttttcacg gtagtagttg taccatgatg
     1801 aaattcctgc ctcggcaatg ataacttcta aaccatcgac tcctgtagtc gcaagaccat
     1861 tggacatggt acctagatag gaaagtcctg ttgtagcaac ttttccgttt gaccaatcag
     1921 ccttgacttg acgctggcgc gtgtgatcag taaaggcacg gcaacggccg ttaagccaat
     1981 cgatgacatt tttataagcc tcgatttgct ggtagtctcc attagtcatg aaacctgtcg
     2041 agtctttggt accaacacct gagacataga gattggcaaa gcctctcgga aggaagtagt
     2101 cgtttagtgt atagctagag ttgatgtgag ttagcttttc ctcagcctct gctataagct
     2161 cagctttacc ttggggttgg acgagattta gttgaggttt ctctagctca atcttgtgag
     2221 gaagcttaac ctcaagctcg ccctccatct tgtagagagc cttgtcacta gccttgtcat
     2281 tggttccctg atgataaggg ctggctgtca tgatggcagg gatttttcca tcaaaacgag
     2341 ggcgaataat gctaaccttt actaggtctg atagcccttt ttggtcagta tcgacacgag
     2401 actcaacgta aacgacttca cgaatgacat cctggttaga aaaagtagcc aaactcttgc
     2461 cgttaaagta gtggtagtca ttatcctccg gaataagacc atcactaaca agttggtcga
     2521 taagagtatt tccttttttg gtgcgagtat tgagtaactg atagagattt tcaatcaagt
     2581 caccatatat aatgggaaat ccagtttctt tacgaaaaac gtcactatct tcgaagtcaa
     2641 ccaaataaga aaagcctaaa agttgaaaag caacagtata aaaaatatct gctgtcagtt
     2701 catcttctga ttgaaaaaat gtcagcaggt ctgttttttt atcagctgct aggatagaaa
     2761 gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg taaaaaggtt tcaagtgagt
     2821 ctttgtgatt ggctgtattt tgtaaatcaa agccacattt ttttagttca gataagacat
     2881 tttcttttgg aaaattgata taactatatt gattaaaacg catagaacct ccatatagaa
     2941 tgacagttaa ggttattata tcaaaaaaaa agcagaaagg gaattgttaa cttcaaaagg
     3001 aaataatcca ataaaaatga ataaagtact aaattcaata tagagaacag agtaacaata
     3061 agaataaata gatagggtat a
//
LOCUS       DBERDS010000081         3057 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.081, whole genome shotgun sequence.
ACCESSION   DBERDS010000081 DBERDS010000000
VERSION     DBERDS010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.081"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..511)
                     /locus_tag="ACL73E_001958"
     CDS             complement(<1..511)
                     /locus_tag="ACL73E_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HGS0801850.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTKTESFANLIQYIRKQYSLQNINNIQSLLSDS
                     SNYTLDSFEKTMVKSILHTMDSRIIPSDDELLQLADYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLT"
     gene            593..664
                     /locus_tag="ACL73E_001959"
     CDS             593..664
                     /locus_tag="ACL73E_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGS0801851.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            768..1637
                     /locus_tag="ACL73E_001960"
     CDS             768..1637
                     /locus_tag="ACL73E_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HGS0801852.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            1624..2346
                     /locus_tag="ACL73E_001961"
     CDS             1624..2346
                     /locus_tag="ACL73E_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGS0801853.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            2419..2874
                     /locus_tag="ACL73E_001962"
     CDS             2419..2874
                     /locus_tag="ACL73E_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801854.1"
                     /translation="MIVLYDSFDSIVNCFDKLKGQYILLPVAFESSVKNYSWKDFNFE
                     YHKRIEIVDSFHSFTKGMVLIENCNYKINRAIIQPATEILMLNYLKKKSMDLRIDFTH
                     SKVMANKKFLEEGYRFSIVSQETIINNDDIIICETFSPEMIWCLYRVKG"
     gene            2878..>3057
                     /locus_tag="ACL73E_001963"
     CDS             2878..>3057
                     /locus_tag="ACL73E_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801855.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYI"
BASE COUNT         1131 a          333 c          537 g         1056 t
ORIGIN      
        1 tagttaataa gaagtaggag ttgtagttaa ttgttcgtac acagttacct aataaaataa
       61 tctcataata accccatttt tcaactttaa agagataatc tgctagttga agtaattcat
      121 catctgatgg aatgattctt gaatccattg tgtgtaaaat ggattttacc attgtttttt
      181 caaaagaatc taaagtgtaa tttgaggaat ccgaaagtag agattgtata ttattgatgt
      241 tttgtaatga atattgttta cggatatact gtattaagtt ggcaaatgac tcagtttttg
      301 tatagtcttc atcgtgtaaa ataagaaact catccaaagt aatgtgtaat ttgtctaaaa
      361 tattgatcag tcggatacat gatatctctg actctccacg ttcaaatcgg gatatttgcg
      421 attttgaaag atgctcatca gcaacagagc atagactgat ttgtttgcct ttacgaactt
      481 ttctaagtgt gatgccaagt tttgatttca tagtttttcc cattctccca acaaaaagtt
      541 aacttagttt tatttattgt acaataaata aaaattgaaa ggaagtctaa atatgaagaa
      601 aatttcaaaa tttttcccaa ttttgatgct agtgatggac attatcatta ttgttggtgg
      661 ttaaatcact taggtgtaca cctaagtctt tagagtatct aaagactata cttactagct
      721 aaaacatatt taagttaaat cgtaaaattt tagagagtgg tgagactttg aaacataaaa
      781 aagtattaat tatagggtat ggtataatga ctcggggtat attaaaaatc ctgaaacagt
      841 cgaaaaaata taatatatac ctatatagta ggcatctaaa ttcaacaata aatggaataa
      901 tatttattag agaagatgaa ttacctgatg ctataaatca ggttgatttt ataatcactt
      961 gttttagtaa tcatattgaa acggataatt tcattaatga gtttttatta aatatacaat
     1021 cacttcgtaa aaccatagta attgatttta caacctccag gattgattgc gttgaaaaat
     1081 ttaaaaaaac tgttgaaatt aaagggggat actatataga ggctcctttc acaggaggta
     1141 agttaggaag taatagtggt caactatcaa tttttttaca tattgatgaa ggtgtaaact
     1201 ataataaaaa ggagttaatg gaattattaa aattaatttc aaaaaaaata tacttttttg
     1261 aaaagagtac ggaaccaaca aaattcaagt taatttataa ctcgtgggga gcgtatttgc
     1321 tttactctat taagctattc aaccctttac agtatgattt ttcaccaaag tctctagagg
     1381 tagcgaatac aatcgtatgt aatgatggtt ggatgagttt agtatgcaac tccaaattag
     1441 aacagatcaa tgatcaagat tttgatgaca tacactttag agtagaatat atggtaaaag
     1501 atttagaata tgctaatttt tcagtctttc atgatgaagt gaaagaaata aattatttat
     1561 tacagcaata tagggattgc ttagtaactg atagtggaaa agattatacg gtaataggaa
     1621 agtatgataa cttataggaa tgacttgctg tctaaagaat tagatatact aatttcattt
     1681 tttaaaaaat gcgaggtagg aaaaatttca ctcgttatta ctggttcctt ggcaagaggt
     1741 aatccaagaa tcaaggatgg gaaattagaa tcggatattg atattctagt tatagtagac
     1801 agtattcagc aattaattag tataaaaaag actttagagg gaaggtttca ctttgtacat
     1861 aaaatttctt tgattttttg tttgaaggaa agaataaatc gaagtcgtta tcgtggaatt
     1921 attaatagta ttagaagtgt agataatctt ttagtagata atctgcatat aaaaaatcaa
     1981 ataatagaag ctttagactc acctaccaat attgtggagc agactcgctc tatgattcag
     2041 gaattttgtt attattcatc aaaatattta atttcaaaga ataattattt ggaattaaaa
     2101 ctagaaaagt attggaagga gattgcaaca ttaaatcata tcgataaaaa gataaaacac
     2161 ctagattttg aaagaatatt tgctgtttta aaagaacaca aaatacaaat tttggattca
     2221 agtgaatatt ttttccaaaa tgtaaaaact tctgagaata tttatttaga gatgagggat
     2281 ttagtatctt tggaaaatca aggattagac tttgaacatt gtattttgag cttgggggaa
     2341 agatgataat aaatacatta ggaccaactg caacagattg ttttttatgc aataaatcgt
     2401 ataaaattaa aagtagatgt gattgtactg tatgatagtt ttgatagtat agttaattgc
     2461 tttgataaat taaaagggca atatatatta ttacctgtag ctttcgagag tagtgttaaa
     2521 aattatagtt ggaaagattt caactttgaa tatcataagc ggattgaaat tgtggattct
     2581 tttcactctt ttactaaggg aatggttcta atcgagaatt gtaattataa aattaatagg
     2641 gcgattatcc aacctgcaac tgagattttg atgttaaact atttaaagaa aaaaagtatg
     2701 gatctgagga tagattttac ccatagtaaa gttatggcaa ataaaaaatt tctggaagaa
     2761 ggttatcgtt tttcaatagt aagtcaagaa acgataatta ataatgatga tattattatt
     2821 tgtgaaactt tctctccaga aatgatttgg tgcttatata gagtgaaagg atagaaaatg
     2881 ttttctgaaa ttattaagaa atatgatatt gttacactga aagatagtgg ttttttgaga
     2941 ggtgattggt tcataggttc agcgttaatg gctcatgact atgaaagcct taaggaaggg
     3001 atatatttct atccccagga aacaatttgg acaagaatct tggatttaga atatata
//
LOCUS       DBERDS010000082         2919 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.082, whole genome shotgun sequence.
ACCESSION   DBERDS010000082 DBERDS010000000
VERSION     DBERDS010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.082"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(108..641)
                     /locus_tag="ACL73E_001964"
     CDS             complement(108..641)
                     /locus_tag="ACL73E_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGS0801856.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(730..1506)
                     /gene="recX"
                     /locus_tag="ACL73E_001965"
     CDS             complement(730..1506)
                     /gene="recX"
                     /locus_tag="ACL73E_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGS0801857.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1544..2899
                     /gene="rlmD"
                     /locus_tag="ACL73E_001966"
     CDS             1544..2899
                     /gene="rlmD"
                     /locus_tag="ACL73E_001966"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGS0801858.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          925 a          527 c          535 g          932 t
ORIGIN      
        1 gtgttgtaac tctgctataa tggatttatt cctttttgtg tttacacaat ttattttata
       61 ctaccaaaaa aacaaggtca ggattttgtt cctgaccttt gacaacttta ccgattcttt
      121 agttctacat agcgcttgta ccaaatgttt acataggctt ctgagaaagg accacgtcca
      181 ttgttaatcc aatcaacaag aattttgaca tgttctttta aaatatagtc caagtcatca
      241 gaataattca ttttgcgttt gtgacgctcg tactcttcaa cgtccaagag acgtttttcc
      301 ccatctgtaa aaattttaac atccaaatcg taatcaatat acttcagtgc ttcttcatcc
      361 agatagtagg ggctagccat attgcaatag taagaagttc cattatcacg aatcatggca
      421 atgatattaa accaatattt cttgtgaaag taaacaatag ccggttctcg agtgacccaa
      481 cgacgaccat cactttcggt aacaagtgta tgatcgttga caccaataat ggcgttttct
      541 gttgttttta gtaccatggt gtcccgccaa gttcggtgga gactcccatc atgcttataa
      601 ctttgaattg taataaagtc gccttctttt ggaagcttca taactaacca actttctaca
      661 atttataagt ttatcattta ctattgtacc ataaaattac ctaaaatctg tgaatttcac
      721 ttggaaatat taaagatatt ctctaagagc gcttgctata tccgaaaaat cgtagccctt
      781 tcgtgctaaa acttgagtta aacgctgctt cagttcgtat ccttcatact ttcgagcata
      841 cttagtatat tgcttatcaa gttccttgaa gatgagttct tgagtcgttt cttggtcaac
      901 ttggctatct aagtcgtcaa aggcaatttt agcatcagaa taagagaagc ccttgttagt
      961 caagttctgg ataatcttat cttgcagggc acgagatgga agttttccct catatttttt
     1021 caatagttta ttagctacac gttgagcaac ttcagaaaaa tcaaattctt tcaagttctc
     1081 ttctatagta gattttgaaa tccctttttg agctagtttt tgagtcagca cataaggacc
     1141 cttgtctcct gaaagttgat tggtattgat gatagcataa gcgtactgac catcattaat
     1201 ccacttatct tctttaagat tagcaataac ttgagaaaca atgtttttat caatatcgta
     1261 ttttttcaga tattctctga cttctttttc agtgcgtgct ttaaaggata agtggtagag
     1321 ggccagattc ttaccataag aaaattgagc aaagtcttga atctctttca attcctcttc
     1381 gcttatcacc ttatctctcg ataacataaa acgaacaatt gtatcttcgg tgatatagca
     1441 tttgtcgcca ttatcaagct ccatcagata gagtcttttt ttcttttcaa gttttgtgat
     1501 tttcatagct ctattataac tcaaaatgtg ataagatagg ggtatgaatc tgaaagtgaa
     1561 acaaaaaata ccattaaaaa tcaagcgcat gggaattaac ggtgagggaa tcggctttta
     1621 ccaaaaaaca ttagtctttg taccaggagc tctcaaaggc gaagatatct attgtcagat
     1681 tacttctatt agacgcaact ttgttgaagc aaaattactg aaggtcaaca agaagtctaa
     1741 atttcgaatt gtgccatctt gtactattta taatgaatgc ggaggctgcc aaatcatgca
     1801 cctgcattat gataagcagc tggagttcaa gacggactta cttcatcaag cgctgaaaaa
     1861 atttgctcct gcaggatatg aaaattatga aattcgtcca actattggaa tgcaggaacc
     1921 aaaatattac agagctaagt tacaatttca gactcgaaaa tttaaaaatc aggtcaaggc
     1981 gggcttatat gcacaaaact ctcactattt agtagagttg aaagactgcc tggtacaaga
     2041 taaggaaacc caagtgattg ctaatcgctt agcagaatta cttacttatc accagattcc
     2101 aatcacggat gagagaaaag ttctaggtgt ccgtactatt atggtccgac gcgcgagaaa
     2161 gaccggacag gttcagatta ttattgttac aaaccgccag cttaatttaa ctcaattggt
     2221 aaaagagttg gttaaagatt tcccagaagt tgtgacagta gctgttaata caaatacagc
     2281 taaaaccagt gagatatatg gtgaaaagac agagattatc tgggggcaag agagtattca
     2341 agaaggtgta ctcaattatg aattttcact atcccctcga gctttttatc aactaaatcc
     2401 tgagcaaaca gaagtcctct atagcgaagc agtaaaagcg ctggatgttg ataaagaaga
     2461 ccatttgatt gacgcttatt gtggagttgg aacgattgga tttgcctttg caaagaaagt
     2521 aaaaacactc agaggtatgg atattattcc agaagctatt gaagatgcca agcgaaatgc
     2581 taaaagaatg ggatttgaca atactcatta tgaagctgga acggcagaag agattattcc
     2641 tcgttggtac aaggaaggct accgagcaga tgctttgatt gttgacccac cacgtacagg
     2701 tctggatgat aagttattag atactattct tacttatgta ccagaaaaaa tggtttatat
     2761 ttcttgtaat gtttcgacct tggctcgtga tttggtacgc ttagtagaag tctatgatct
     2821 tcattatatc cagtcggtcg atatgttccc acatacagct cgaactgaag ctgttgtaaa
     2881 attaataaaa aaagtttaaa aaaggtgttg acaaaacat
//
LOCUS       DBERDS010000083         2902 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.083, whole genome shotgun sequence.
ACCESSION   DBERDS010000083 DBERDS010000000
VERSION     DBERDS010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.083"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            426..1772
                     /gene="gdhA"
                     /locus_tag="ACL73E_001967"
     CDS             426..1772
                     /gene="gdhA"
                     /locus_tag="ACL73E_001967"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGS0801859.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2268..2438)
                     /locus_tag="ACL73E_001968"
     CDS             complement(2268..2438)
                     /locus_tag="ACL73E_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801860.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2451..>2902)
                     /locus_tag="ACL73E_001969"
     CDS             complement(2451..>2902)
                     /locus_tag="ACL73E_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0801861.1"
                     /translation="LLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTI
                     ISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQI
                     IIAHRLSTIKDADIIFVMKGGKIVESGNHKYLMTLGGEYYSLYTKRK"
BASE COUNT          905 a          538 c          499 g          960 t
ORIGIN      
        1 tttgaaggcg tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggctt
       61 ggatttcttc tttagttgat ttcatatcac tattatataa tgatttttga ttttagtctg
      121 gtataaatat tgctttcctc caaaatggtc ataattttac tagcaaatct aacatatcac
      181 ggataaatta acaagtgatt tctgaattac taaacatttt cttttcttat agcataccat
      241 actttaagat tttgtctttg agaaagatat ttccaagaaa aacgttcgtt tttttatcta
      301 ttttcaaaaa aaccaaaaac tgaattgaaa gaatttttag aaaatttctg ttttttcttt
      361 acagtgaaaa aaaattctgc tataatgtct tatgtaataa aatatgacaa taaaaggaga
      421 acgatatgac atctgctaaa gaatatatcc aaagcgtgtt tgaaactgtg aaagctcgta
      481 acgggcacga ggctgaattc ctccaagctg ttgaagaatt tttcaacact ttggaacctg
      541 tatttgaaaa acaccctgag tatatcgaag aaaatatctt ggcacgtatt actgagcctg
      601 agcgcgtggt ttctttccgt gttccttggg ttgaccgtga tggaaaaatt caagtaaacc
      661 gtggttaccg tgttcaattc aactcagctg ttggaccata caaaggtgga cttcgtttcc
      721 acccaactgt aaaccaaggg atcttgaaat tcctcggatt tgaacaaatc tttaaaaatg
      781 tcttgactgg acttcctatc ggtggaggta aaggtggatc agacttcgat cctaaaggta
      841 aaacagatgc tgaagtgatg cgcttctgcc aaagcttcat gactgaattg caaaaacaca
      901 tcggaccatc acttgacgta cctgctggtg atatcggtgt tggtggacgt gaaattggtt
      961 acctttacgg tcaatacaaa cgtcttaacc aatttgatgc tggtgtcttg actggtaaac
     1021 ctcttggatt tggtggtagc ttgattcgtc cagaagcaac tggttacggt ttggtttact
     1081 atactgaaga aatgctcaaa gctaacggta acagctttgc tggtaagaaa gtcgttattt
     1141 caggttctgg taacgttgct caatatgctc ttcaaaaagc aactgaactc ggtgcaactg
     1201 ttatttctgt ttctgactca aatggttatg tcatcgatga aaatggtatc gacttcgatc
     1261 ttttggttga tgttaaagaa aaacgtcgtg ctcgtttgac tgagtatgca gctgaaaaag
     1321 caactgcaac ctaccacgaa ggtactgtat ggacttacgc tggaaactat gacattgctc
     1381 ttccatgtgc cactcaaaac gaaatcaacg gtgaagcagc taaacgtttg gttgctcaag
     1441 gcgttatctg tgtatctgaa ggtgccaaca tgccgagcga ccttgatgcc atcaaagttt
     1501 acaaagaaaa tggtatcttc tacggacctg caaaagctgc caacgctggt ggtgtagccg
     1561 tttcagctct tgaaatgagc caaaacagtc ttcgcctctc atggactcgt gaagaagttg
     1621 atggccgtct caaagacatc atgacaaaca tcttcaacac agctaaaacg acttcagaaa
     1681 catacggtct tgataaagac taccttgcag gagctaacat tgctgccttt gaaaatgtag
     1741 caaacgctat gattgcccaa ggtattgttt aagatttatt tgcttaatcc tcaatcacta
     1801 cgattgggga tttttagttg agttagacag ttgggaaatt ctaattaaat gaaataaaaa
     1861 ctgaacaaat tgattgcgga attcaaacca atttctaaca tacttctaga aattaatttg
     1921 acttttctaa tcgatttgtt catatcttat ttcaatttac tatacttact taaccctttt
     1981 tatactcaat gaaaatcaaa gagcaaacta ggaagcgagc cgcaggctgt acttgagtac
     2041 ggcaaggcaa agctgacgtg gtttgaagag attttcaaag agtattaaac aaaaagaaaa
     2101 accgctactc ctaagaatag cgatttaatc atgtttttaa gctactactg tagttgctct
     2161 attatttaag tgttatgaat aacttcaata tctttaaagc tttttgttag atttataatt
     2221 tcaactatag ccatctctac tccttagttt acagcaaaaa attatgctta attcttattg
     2281 tttttgtaaa caatcagcga acccaatact attccattca acaagcctaa agaaatacca
     2341 tattcaactg gaaaatctaa aaaaattgca aacactattc caatcatcac ccctagtgag
     2401 gctattgtta aaattacata ttcattttct ttcttcattt tctttacacc tcatttcctt
     2461 tttgtatata agctgtagta ctctccacca agagtcatta agtacttatg atttcctgac
     2521 tcaacaatct taccaccttt cattacaaaa ataatatccg catccttaat cgttgacaat
     2581 ctatgagcta taattatttg agtacaaccc tgactttgta tatactttgt tattctttcc
     2641 tcattaatag tgtctaatgc actagttgct tcatctaaaa ttacaatact aggattattt
     2701 attaatgcac gtgccagtgc tatccgttgc ctttgcccac ctgaaatatt tgaccccatc
     2761 tctgagatga tagtattaaa tttcatcggc atagccatga tttcatcata gatttgaact
     2821 gctttacaaa cttcctctat cttttgtgaa gtaacttcgt gctttaaagt tatattatca
     2881 agaatacttc tgttcaataa aa
//
LOCUS       DBERDS010000084         2899 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.084, whole genome shotgun sequence.
ACCESSION   DBERDS010000084 DBERDS010000000
VERSION     DBERDS010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.084"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..489)
                     /locus_tag="ACL73E_001970"
     CDS             complement(<1..489)
                     /locus_tag="ACL73E_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801862.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFLNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSK"
     gene            complement(547..1260)
                     /locus_tag="ACL73E_001971"
     CDS             complement(547..1260)
                     /locus_tag="ACL73E_001971"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGS0801863.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIGRDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1719..2099)
                     /gene="dhaM"
                     /locus_tag="ACL73E_001972"
     CDS             complement(1719..2099)
                     /gene="dhaM"
                     /locus_tag="ACL73E_001972"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGS0801864.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2099..2173)
                     /locus_tag="ACL73E_001973"
                     /pseudo
     CDS             complement(2099..2173)
                     /locus_tag="ACL73E_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
     gene            complement(2521..>2899)
                     /locus_tag="ACL73E_001974"
     CDS             complement(2521..>2899)
                     /locus_tag="ACL73E_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGS0801865.1"
                     /translation="RNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPK
                     PTEEPEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLF
                     GTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          894 a          557 c          453 g          995 t
ORIGIN      
        1 tttagaaact tgccatatag tctttaaata atttttttct aaaaagtcgt caaaattaga
       61 aaaaaatcga aaatacaatg cattctcttg gtgtaaaatc gctcttttta aaggataata
      121 ctctttaata ttattaactt tttgttcgta ggcatatttt gctacatgat ctaggtatat
      181 atcaaaaaag tcatgaggaa aatctcccat acagccatta cgattcatat tgaggctata
      241 ttttcgatta gtaagataat tcagaaatat atttcctatt actctaagat tatctacttg
      301 tgaatccctt ctcccaatat aatccccttc tttgactaat gatggagatt tccaagtaaa
      361 aattaaatcg ccagagaaat ttttcttatc aaaaaactta aaaagagatt gataaatact
      421 atttgctaat tgacaagtgt cagatgtaaa ttcataatta acagcttcat taaaatcaac
      481 ttcagacatt tcaatgtact cttcaatagt aatattagct tttttgtagt cattagctcg
      541 tctcctttaa aatgtgatct tttcaagaat atttttatct aaacaatcca gcaagtcttg
      601 gtaagaatag acttcgtaag tcggctgggc ttgtgtgtga ttttcgaggt gatgaggatt
      661 ataccagata gtgtcaatcc ccgcattatt gccaccttga atgtcggcgg ttagagaatc
      721 tccaatcatc agcgtctttt ctttactaaa tccagcaatt tgctggccaa tcttttcata
      781 aaaaagagca tccggctttt gagtttgcaa ctgttctgag ataaagactt gattgaaata
      841 aggtgctaga ccagattgag ccaaacgtcc tgtctgaatg gcagtaatgc catttgtcgc
      901 agcatacaag ttataatcac gcccaatgag gctgtccaag agatcatgag cgcccgatag
      961 tgtttgtccc tgctgggcga ggtaaaattg gtaacgctgg gcaagaaaac taccgtcttt
     1021 ttcttgtcca aaatgagcaa ataaacgaga aaagcgcgtg ttaaccagct cttgtttact
     1081 gattttcttc agctccaagt ctttccagag agccttgttc ataggaacgt aataatcttt
     1141 ataagcctga atatccgcaa ctccttcttc ttttagaagt tgggtcaaag ccacatcctc
     1201 agcagcatca aaatcaagaa gagtgtggtc gaggtcgaag agtagaaatt tgtagaacaa
     1261 tttgaggttt tcctttctga aaattcatta agaacattat atcataaagc acctcataca
     1321 attaactaat ttaatcactt aaaaaaaatt cgaacacttt ctatacaact gacagctcaa
     1381 atctttcaga atagaacaat actaactatc gaacaccctg tcttcataaa tacatatgta
     1441 attctaggcc tagaattcct ataaactaaa tgctttcata ctcttccaag taattgattg
     1501 ccttaaattt taatttttga aggtttctaa agctagaata gccccatcac aatcagtttt
     1561 gattgattca caatttagaa acactatagt ttcactcctg ttaaaataaa aaggaactgc
     1621 ataaagcaat ccctttctga ttttgaaatc atttacttaa cattttatag ttgagataat
     1681 caatagctta tctataaaaa gagttatagt aaaattcctt atttattgat ttcaagctcc
     1741 gctaactgta tttgaataac tgacagttct gcaccagcct gaagaagagc agctgcatta
     1801 taggcacctt ctacaattgg aaccctgttg atgatgatac ttttatcact gaaatcagtc
     1861 accattttta agttcatttt agcagaacct aggtcaaaaa aggcaagtaa agtatctgct
     1921 ggattttcgg aaacaaccct atctacttga tcaaaactcg ttccaattcc tccgccctcg
     1981 gttcctccta cataagtaat cggaacatct ttagctactt tactaatcag ttcaacaaca
     2041 ccttctgcaa tgtgtttgga atgtgaaacg ataacaagac caataccaat actttccatc
     2101 aaaccactcc agtttctaaa atagcagtaa agagtaatcc tgatgagaat gatccaggat
     2161 caatatgtcc aagaaaccac atgctcctaa gacaagagct aacagactgg ccatcaataa
     2221 tagtattgtt ctttttttca tcattactcc ttaactagtg tttaactgat taattagcca
     2281 gtaaatagtt tatctttatt tacactatct gttaagatat agtaaaatga aataagaaca
     2341 ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtatactat tctagtttca
     2401 atctactata ttttgcacat tttcatgaaa aaaatgagaa ctagaactca cattctgctc
     2461 tcatttttcg ttttcccgtt ctcctatcct gtttttagga gttagaaaat gctgctacct
     2521 ttacttactc tcctttaata aagccaatag tttttcagct tctgccataa tagtattgtt
     2581 gtcctgggtg ccaaatagta aattattttt taatcctgtg agagtctctt tggcattgga
     2641 cttgataatt ggatcctgga tttttccaag taaatcttca gcctctctca gtttttcttc
     2701 aaccttttca gtctcgacct gaggttcttc tgattcctct ggtgattctt ctggttcctc
     2761 tgttggtttt ggagactctg gtttctcgct ttgcggtttc tcttctcgag gggtttcttc
     2821 ctcaggtttt tctgtctgag gtttctcctc gcttggtttt tccgtttgat tggtatcagc
     2881 ttgaccattt ttgtttctt
//
LOCUS       DBERDS010000085         2636 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.085, whole genome shotgun sequence.
ACCESSION   DBERDS010000085 DBERDS010000000
VERSION     DBERDS010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.085"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            12..479
                     /locus_tag="ACL73E_001975"
     CDS             12..479
                     /locus_tag="ACL73E_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801866.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTIIVKKKKICYNEFKLRN
                     RKQKGVIMWVLGFILFMIFFYSNNSKKIKKLEKKIKRLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            489..695
                     /locus_tag="ACL73E_001976"
     CDS             489..695
                     /locus_tag="ACL73E_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGS0801867.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            695..892
                     /locus_tag="ACL73E_001977"
     CDS             695..892
                     /locus_tag="ACL73E_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801868.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            895..1629
                     /locus_tag="ACL73E_001978"
     CDS             895..1629
                     /locus_tag="ACL73E_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGS0801869.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1641..2282
                     /locus_tag="ACL73E_001979"
     CDS             1641..2282
                     /locus_tag="ACL73E_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGS0801870.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2300..2530
                     /locus_tag="ACL73E_001980"
     CDS             2300..2530
                     /locus_tag="ACL73E_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801871.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          777 a          436 c          538 g          885 t
ORIGIN      
        1 gaagagtatt aatgatagat aaagtggtca ggaacctact cctgaccttt ttcttttgca
       61 aaatgacaaa aatcataaac tttttgacaa ctataattgt caaaaagaaa aagatatgtt
      121 acaatgaatt caagttaaga aataggaagc agaaaggagt tataatgtgg gtactaggat
      181 ttatactatt tatgattttc ttttattcta ataattctaa aaaaatcaag aaactagaga
      241 agaaaatcaa aagacttgag cgaaaagaga aaggaaacgc agaaatgtcg agattattac
      301 aagaaatgat tggaaaggaa ccaattataa cgggagtgta tattgggcca gataactggg
      361 aagttgtgga tgttgatgag gaatgggtaa agctacgacg tgtagataat acgggaaaag
      421 aaaaattcaa gttgcaacgt attgaggata tccaaaccgt tgaatttgac ggagagtagg
      481 tgtgtaacat gcaactaaaa aatcgtctaa aagagcttcg agctcgcgat ggtctcaatc
      541 aaaccgacct agccaaactg gcaggggttt ccagacagac cattagccta ctagaacggg
      601 atgagtacac cccatccatt atcattgccc tgaaaatatc tcaaattttc aacgaaacag
      661 tcgaatcggt atttcgtttg gaggaggacg agtgatgaac aagtataaag tgatttatta
      721 tgtagtggtc atagctttat tagtcagcgt atttctactg attgggatgg acctaagctg
      781 gtttaatccc tatcaaagcg accaatttgt ttgggtctac tttgctctca tcccagtaat
      841 tgaatggatt gaaaagaaat ccaaaaatct agcaagtgaa aaaggagaat gaatatgaaa
      901 aagaaacgta gattgttatt tttgatgtct attgtcttgg gggggttctt gggcatgttt
      961 gtagggatgt ttaaggcacg tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg
     1021 atgccatgga tatcagctat ttgtttactg ataggtttca ttagtatgtt tttgactttc
     1081 aatttcttaa agaaaagcag aaaatttcat tccttgtatc aagaggaaat ggatgacgat
     1141 ctgaatgaaa cctattatgt gcaaatgtat cggaatcttg agtttggaac cattgctttt
     1201 aatattacag gtgtagcgat tccattggct atttttattt cattaagtga ggtgattata
     1261 ttgcatacaa accctcaaac atttttcctt tctttcttac tctttgtggt attcttagtc
     1321 gctcaaaaat ctctttttaa aaccattgcg attgttcgtc agtttgattt ggaatttttc
     1381 gctacaccaa aggatgtctt gaactatata aattcttatg atgaagggga gcgtcaggct
     1441 aatttggaac agagttttcg aattttattc caattacacc aatatgtctt accagcctta
     1501 tatatttttc ttattatcat ttctttcttg acaggagaga ttcagttact agctttcttg
     1561 cttgtaggag ccatccatgt ttatatcaat gtgatgcagt tacctatggt aaaacgttat
     1621 ttcaaataaa ggagttatct atgaaactac ttaaaaacct tggctggttt cttctagccc
     1681 ttctatcctt tttctttatc tatggcttta ttcaggggct cgcgactgcg tcgcttgctt
     1741 taggcgcttc accctatgct gttactctac tctatgtggt cttggctgga gtatatgtgt
     1801 acggcattta caaatggtat cagaaagctc ctgtttatat tgagaagagc ggctttaacc
     1861 gatttatttg gcttcctgcc ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc
     1921 cagatgatcc ttcagtaaat caacaaatag cgacagactt gaccttgtct caaccacttt
     1981 tctcattctt tgctgtggtt atttttgctc ctttgacgga agagattgtt tttagaggga
     2041 tgttagcacg ctatctcttt cctaagcagg acaatagtaa acgaaccctg atttttcttc
     2101 tggtatctag tcttctattt gccttgattc attttccagg tgatgtgcaa caattttttg
     2161 tctattttag ccttggtttt agtttgggtt tggcttacat tagcagaaaa ggtctggtct
     2221 acagtatttc tcttcacgct ttgaataatt tagtcggctt tttgatgatt ctcatgctat
     2281 aatagagtca ggaggtcaca tgaaacgagt aattttatta gcagtgattc aggcagtcgt
     2341 tctatttttc atcattggag cgctagctta tgccttcaaa ggcgatttct tctataacta
     2401 tctagcagtt gtctttgctc ctattgcagg tgtactgcgt tttgggacgg cttacataac
     2461 ggaaattgtc ttgcctcgaa aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa
     2521 ttcaaaataa aagagtccgg tgaagttcat cggatttttg tattatactc aatgaaaatc
     2581 aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgt
//
LOCUS       DBERDS010000086         2440 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.086, whole genome shotgun sequence.
ACCESSION   DBERDS010000086 DBERDS010000000
VERSION     DBERDS010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.086"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..236)
                     /locus_tag="ACL73E_001981"
     CDS             complement(<1..236)
                     /locus_tag="ACL73E_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HGS0801872.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKY"
     gene            complement(288..1724)
                     /locus_tag="ACL73E_001982"
     CDS             complement(288..1724)
                     /locus_tag="ACL73E_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGS0801873.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            complement(1914..2252)
                     /locus_tag="ACL73E_001983"
     CDS             complement(1914..2252)
                     /locus_tag="ACL73E_001983"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGS0801874.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
BASE COUNT          828 a          516 c          296 g          800 t
ORIGIN      
        1 ttatacttca atttataaaa taaaattatt cctgagagta gaaacgaaac actatttgct
       61 aaaatcaaag gcaagtctcc tatacgaata ccatgagcaa gccacaatgc aataccaata
      121 acttgcataa catacatacc tagagcaata gatcctgtgt cctttgtctt aactacacga
      181 aaaacttgtg gtaaaaatgc aaatgttgtt aaaattgctg caatacttcc aatcatatgt
      241 ctcctcaata tgctaaacaa actgagaata atctcagttt gtttatacta ttctactgat
      301 tcaccgttag ataaaataac tttcttatac cagccaaaag attttttcgg ggaacgatta
      361 taacttccct tcccattgtc atctttatct acataaataa agccataacg tttccgcatt
      421 tcaccggtac cagctgaaac caaatcaata catccccatg gagtataacc cattaaatca
      481 acaccatctt caactacagc ctttttcatt tcacgaatat gggcacctag atattcaatt
      541 ctataatcat catgtaccat accatctgct gcaacttgat ctatagctcc aaaaccattt
      601 tcaacaataa agagtggtaa gtgatagtgg tctgtaaacc aatttaacgc ataacgtaaa
      661 ccttctggat caatttgcca ctcccattca gaagccttaa cataattatt tttcactaaa
      721 tcttctgttt caagataatc aaaataagga ttattttcac gatgagagtc tatagcaaag
      781 gacatatagt aactgaaacc aatgtaatct acagtcccac caagtaaatc ttctttatcc
      841 tggtcagtaa aatcaactga aatacctttt cgttcccaat acttgaaaat atgctcagga
      901 tatttaccta aaacatgcac atcagcaaaa taataacgct tctgcatagc tttcattgcc
      961 attaagatat ccttaggatt gcaagtaact ggataaattg gacacatcgc aatcatacaa
     1021 cctatttgaa aatctggatt aatctcatga ccaattttta cagctcgtgc agaagcaact
     1081 aattcgtaat gtgctgcttg atacataatt gcttctctat tatcaccttc ctcatataca
     1141 atacctgagt tagtaaatgg tgcaaaatct tcctgataat tcgcttgatt attgatttca
     1201 ttgaaagtca tccaatattt aaccttatct ttgtaacgtt taaatacgac ttctgcaaaa
     1261 cgagcaaaga aatcaatcaa tttcctattt ttccaaccac catattcggt cactaagtga
     1321 taaggcattt caaaatgaga tagagtgatg acaggttcaa taccattctt taagcattca
     1381 tcaaaaagat tatcataaaa ctgtaatcct tcttcattcg gctctaactc atcacctttt
     1441 ggaaagatac gtgtccatgc aatagaggta cggaagcact tgaatcccat ttcagcaaaa
     1501 agtgctatgt cttctttata acgatgataa aaatctatcg cctcatgatt tggataatat
     1561 ttaccctcta aaactcccaa agtaatttca cgagctactc catggcgacc agcagtcata
     1621 acatcagcaa cactaattcc tttgccacct tcttgccatc cgccttcaag ttgatgagca
     1681 gcaacagcac caccccataa aaatccatct ttaaaagtag tcatcttttt tcctcctgac
     1741 tttgatattc ttattataaa cctcaaacca aaagatgaaa acgtattctt tttccttatt
     1801 attaaggaaa gaagtaattt ttaatggaaa tagaacaata tcttcttgta ttctcgtaat
     1861 gatatcttta cgattttcaa tactttcaaa ctacaaaaac tctcacaata attctaattc
     1921 cctgtgtcta taaacgactt atcgctttct ggcatcccag aatcatcttc tatataacgt
     1981 tcaacttgca tctgcaagtg atattttttt cttaaatcta agattttctg cattgtattt
     2041 gattgatgat gttcatctaa agcttcttga tttatccact gatcaataag gagaataatt
     2101 ccctcttttt caattggtaa aaaatattcg tatttcaaat tacctttttg acatctaatt
     2161 tctgcgacaa gcccagattc aagcatttct cttgcaaact ttattgcaca atctccatcg
     2221 cctttataat atacatgaat agtcaatgtc atctcatatc ctccaaaatc atccttcaat
     2281 tttaaaaaaa caagtttaga tgaggatcta aacttgtttt ttatgaacta attatctaac
     2341 gtttcgccat tactttcaat cacttcttta taccaataaa atgatttttt cttatagcga
     2401 tttatagtca attgaaacaa gaacaagaca aaagagcctc
//
LOCUS       DBERDS010000087         2391 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.087, whole genome shotgun sequence.
ACCESSION   DBERDS010000087 DBERDS010000000
VERSION     DBERDS010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2391
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.087"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(104..1579)
                     /locus_tag="ACL73E_001984"
     CDS             complement(104..1579)
                     /locus_tag="ACL73E_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGS0801875.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINTIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2314..2391
                     /locus_tag="ACL73E_001985"
                     /pseudo
     CDS             2314..2391
                     /locus_tag="ACL73E_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          713 a          527 c          439 g          712 t
ORIGIN      
        1 acaggattac ctttgaaaaa atggactttt tcaagggctt tttgccgtgc tctaaaatca
       61 tcgccaaatc atcaaattga aataagaaat agtttagata aaactattga cttttcttat
      121 agtttgtctt tctcttaatg acgttgatgt gattgacctc tggatcttcc gtcccttgga
      181 gggagcaacc acgttccttg gcaaattgga tatagtcgac aatttctcgt gtgatgcgtt
      241 cgccaggagc caagataggg attcctggag ggtaacacat gacaaattcc ccacagacct
      301 gtccaacaga ttcgtccaag gtcaaacttt ttctctctga atagaaggct tcttgcggag
      361 acagcactaa ctcgggctga atatattctc ctgctatcaa atcttttcca tctcttgaat
      421 agagtctctt aatatcagcc agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc
      481 cgatggaaat ataggccaag atattgccga tatcaccaaa ctcgatctga atgtcgtatt
      541 cgtctcgcaa gaggtcataa acctcgatac ctgttaagcc tattccctga gtgtaaactg
      601 acaacttggt tacatcaaaa tcacagaccg acacaccatc tattaactct tttgagtaag
      661 catagtaacc gccaatggta ttgatttcat gacgagcgta ctcggatagc tcaatgactt
      721 cctcaaacga ctctttacca cgaagggcca agttgcgacg tgaaatatcc aaactagcca
      781 tcaataagta agaggcagat gtagactggg tcaggtttat aatctgacga acgtactcgg
      841 gattcatctg ctccccgatt aaaagaagcg aactttgtgt caaactccca ccagacttat
      901 gcatggaaac tgctgccata tcagctcctg catccatagc agaaattgga agtttaccag
      961 tgaaatgcaa atgcgctcca tgggcttcat ctactaaaac catcatgcca gcttcatgag
     1021 ccatttctgt caaccccttt aggtctgaac agatgccgta gtaagtagga ttgttgatta
     1081 ggatagcctt agcatctgga tggtccttta tggcctgtgc tactcggtca ttttcaagac
     1141 ctaaagcgat accaatctta ggatctacac tcatctcgat atagatggga atggcaccac
     1201 atagaaccaa cgcattgata gcagatttat ggacatttcg tggcagaata atcttatctc
     1261 ctgccttgca ggttgccaga atcatagtct gcaccgatga agttgttcca ccaatcatta
     1321 gaaaggcatg gctagctcca aaagcatctg cagccagctc ctctgcatca cgaataatcg
     1381 aaataggatg gcctaaatta tccaagggtt tcatcgaatt gacatcaatg cctacacatt
     1441 tttctcctaa gagttcgaca agttctggat ttccccgtcc acgcttgtga cctggaacat
     1501 caaagggaac aatccttttc ttgcgtaact tcaccaaggc ctcataaatt ggggcttggt
     1561 tttgatctaa ctctttcaaa acatactcct ttcaatattt ttaggacctt atgaaaacta
     1621 aggaactaaa ggttgactca tgaaaaaaga gcaggttttc acctgctctg caatcttctg
     1681 acgtgtttat tttggtttct gttgagtatg tctgttcccg atgtttccta actctctagt
     1741 agcaaatatt acgtacttta ttgatcgttt cacaagatga cgtgtgcttt caccacacta
     1801 aaaatttatg aattagaaca agtgtcctaa catcaactta taaaagtagg cttttaaccc
     1861 tatcaataat gtggcttttc aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat
     1921 tttttactcg ggtttatatt tgctagaaaa catcatctca ttttctaagc tttattacta
     1981 tatcatgttt ttaagaactt gtaaagtatt ttttgataaa aaataaaaat atagtagatt
     2041 gaaactagaa tagtacacct ctgcttctaa aacattgtta gaaatagatt ttactgtcct
     2101 gatcgatttg ttctgttctt gtttcatttt actatatgtt cgtaaatgaa agttctataa
     2161 tgaagttagc cacccagccc tcctaaaaat tagatggttc aactagccga tagctcttgt
     2221 aggcataaga aaacacctct gtgttatact tgttgttcaa ccacaaacac aagaaaggcg
     2281 cagagatgca agaccattat actacaaaag gcgaacaaag ggaaatcaaa tagagaaatt
     2341 gcctctctgc ttggaaaagt tcctcaaact atccacactg aaatcaagcg t
//
LOCUS       DBERDS010000088         2115 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.088, whole genome shotgun sequence.
ACCESSION   DBERDS010000088 DBERDS010000000
VERSION     DBERDS010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.088"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            44..1069
                     /locus_tag="ACL73E_001986"
     CDS             44..1069
                     /locus_tag="ACL73E_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGS0801876.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1059..2066
                     /locus_tag="ACL73E_001987"
     CDS             1059..2066
                     /locus_tag="ACL73E_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGS0801877.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
BASE COUNT          753 a          296 c          374 g          692 t
ORIGIN      
        1 tattatcgat acaatagact tgaaatatgt ttaaggagtt tttatgaaaa acaaattttt
       61 tctaatagct attttagcta tgtgtatagt ttttagcgct tgttcttcta attctgttaa
      121 aaatgaagaa aatacttcta aagagcatgc gcctgataaa atagttttag atcatgcttt
      181 cggtcaaact atattagata aaaaacctga aagagttgca actattgctt ggggaaatca
      241 tgatgtagca ttagctttag gaatagttcc tgttggattt tcaaaagcaa attacggtgt
      301 aagtgctgat aaaggagttt taccatggac agaagaaaaa atcaaagaac taaatggtaa
      361 agctaaccta tttgacgatt tggatggact taactttgaa gcaatatcaa attctaaacc
      421 agatgttatc ttagcaggtt attctggtat aactaaagaa gattatgaca ctctatcaaa
      481 aattgctcct gtagcagcat acaaatctaa accttggcaa actttatgga gagatatgat
      541 taaaattgat tcaaaagcct taggtatgga aaaagaaggt gatgagttaa tcaaaaatac
      601 tgaagctcgt atatccaaag aattagaaaa acatccagaa atcaaaggaa aaatcaaagg
      661 aaaaaaagta ttatttacta tgattaatgc tgcagataca tcaaaattct ggatttatac
      721 tagcaaagat ccaagagcaa attatttaac agatttaggt ctagttttcc ctgaatcatt
      781 aaaagaattt gagagtgaag atagttttgc aaaggaaatt tctgcagaag aagcaaataa
      841 gataaatgat gctgatgtaa tcataactta tggtgatgat aaaactcttg aagctttaca
      901 aaaagatcct cttttaggta aaataaatgc aattaaaaat ggtgccgttg ctgtaattcc
      961 agataataca ccgttagcag cctcatgcac tccaacacca ctttcaataa actatactat
     1021 tgaagaatac ctaaatcttt taggaaatgc atgcaaaaat gcgaaataaa aaacaaataa
     1081 acctaggcat aatttttgta atctgcctag gtcttcttat tacaatattt ttgtcattaa
     1141 agcttggaac aaaagaaatt aatatcagag attttttagc agcttttgga atgggtaata
     1201 caaatgatga ttttattaaa tcaattatat ataaaagaat acctagaact atttttgcaa
     1261 ttttagcagg ttctagtctt gccataagcg gtgtattgat gcaatcagtt actagaaacc
     1321 caatagctga tccaggtata ctcggtataa acacaggagc aagtcttagt gtagtaattg
     1381 gtctttcttt tttaggaatt tcatcaagca taagccatat aagttttgca atcattggtg
     1441 gcttagtaag tgcaattttt gtatacgcga ttgctgtaag cggaaaagca ggccttaccc
     1501 ctataaaact tgccttatca ggaacttgtg ttagtatggc tttaagcagt tttgtaagtt
     1561 ttttaatttt accgaataat aacgtcttag acaaatttag attttggcaa ataggtagcc
     1621 ttggagcagc tacattatct tctatatcta cactactacc ttttataatt ttaggtcact
     1681 tgatagctat atttatttca tcagatttaa acgctttagc tatgggtgat gaaatggctg
     1741 ttggtcttgg agttaatgtt aataggataa gatcacttgc aataattgca agtgtgcttt
     1801 tatgttcaag tattactgca attggtggac ctattggctt cgtaggtctt atagttcctc
     1861 acttttgtgg cttatttata agcaaagata tacgcacaat gaccatttct tcatctttta
     1921 taggtgcaga gctcttgctt atatgtgata taatcggccg tatgttaggt aaaccaggtg
     1981 aaattgaagt agggataatt actgcaataa tcgggggtcc agtacttatt tatgtaacta
     2041 tgaaaaatag aggggttaat aactaatgca aaatttaatt ataggtattc aaaaaagaaa
     2101 aaatagaata acact
//
LOCUS       DBERDS010000089         2106 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.089, whole genome shotgun sequence.
ACCESSION   DBERDS010000089 DBERDS010000000
VERSION     DBERDS010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.089"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            60..224
                     /locus_tag="ACL73E_001988"
     CDS             60..224
                     /locus_tag="ACL73E_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGS0801878.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            303..1031
                     /gene="yaaA"
                     /locus_tag="ACL73E_001989"
     CDS             303..1031
                     /gene="yaaA"
                     /locus_tag="ACL73E_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGS0801879.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(1309..1857)
                     /locus_tag="ACL73E_001990"
     CDS             complement(1309..1857)
                     /locus_tag="ACL73E_001990"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGS0801880.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
BASE COUNT          638 a          382 c          461 g          625 t
ORIGIN      
        1 gtttatttaa taaatatatg ttataataag gtaaattaag cctaatggag gacaaagaaa
       61 tgggttttta tttgatggtt gcttcaatgc tactcggact gctcgctttg aagataggtt
      121 tttctcagtt caaggagaaa aaagataaat tcttatctat cttaacaagt ttagctggca
      181 cagcccttgt tctcgtggct gtctggttag gatggcccaa ataaatagaa aaacctcggt
      241 caaaccgagg tttttcaaat gaatttcttg gttgtggcta aaaaatatgc tacactatca
      301 atatgaaaat tttaatccca acagcaaaag aaatgaacac agacttgcca agtatcgagg
      361 caattccttt aaaaccagaa agtcagaccg tgcttgatgc cttggctctc tattctgcca
      421 gtcaattgga gagtttctac aaggtatcgg ctgagaaagc ggcggaagaa tttcaaaata
      481 tccaagcttt gaaaaggcaa actgctcaac actatccagc cttgaaactt tttgatgggc
      541 ttatgtaccg caacattaag agagataagc tgaccgaggc ggaacaagat tatcttgaaa
      601 atcatgtctt cattacctcg gctttgtacg gtgttgttcc agccttgtca cccatggctc
      661 ctcaccgttt ggattttttg atgaaattaa aagtcgctgg taagactttg aagagccatt
      721 ggaaggcagt ctatgatgaa gctctgaaga aggaagaagt gattttctct ctcttgtcat
      781 cagagtttga gactgtattt tctaaggaaa tcagagcaaa gatggtgacc ttcaaattca
      841 tggaggatag aggcggtcag ctgaagattc actcaactat ctccaagaaa gcgcgcgggg
      901 cctttctaac agctttaata gaaaatcaag tacaaactgt gggggaagca cgtcgcttga
      961 actttgctgg atttgtttac cgagaagatt tgtcacaacc acagggattg gtttttgtaa
     1021 aggaagtata gaaatcagat attttgtatt tggcaatatg tatcatcagc tgttttagtt
     1081 tataaatgag aaaaaaagcg aacaagctag tcttctgagt gtcagaaaag tagtcttgtt
     1141 cgcttttatt atgttatact cttcgaaaat ctcttcaagc cacgtcagcg tcgccttacc
     1201 gtatatatgt cactgacttc gtcagttcta tctacaacct caaagcagtg ctttgagcag
     1261 cttgcggcta gcttcctagt ttgctttttg atttttattg agtgttagtt acttgatagc
     1321 ttcgaccaag tcttgagctt gtttttcaag tgagtttagg actgtttctt caagaaccaa
     1381 ttttccgtct gcccaggcag agtcattaac acgtgcagca gtgaaatcac caacgccttg
     1441 tgtacggata aatggcaaga ggtctttgta gatagcgaaa agttgatcgt gccctgcatt
     1501 ggctacagat gatactgtga caaacttgtc ttgaagggca gaaacgccac gtgtatcaga
     1561 caagtcaagg gcacgagata gccagtcaag caagtttttc actgtaccag ggatagagaa
     1621 gttgtagact ggagagaaaa tccagatagc atccgcaacg agaactgctt cacgagcagc
     1681 agctacagct ggatgtgttg gaacttccaa atcttggctg aagagaggaa gggctgaata
     1741 atcaaggtag ctaacttccg ctttaccagc aagagctttc tcagcttcga gcgccatttg
     1801 gtggttgaaa gaaccttgac gtagtgatcc gacgataaat aatacttttt tagacatgat
     1861 gtgtctcctt tttcttaaaa tttcgagaac tctctcgttg ttataaaata tattacaaca
     1921 aaacaaaaga acttgcaaga aatttgctca gagtttattt gaaaattgta aaatttcgga
     1981 aactctagtc atttgtgact gaaaaagtaa gaactgtttc actttcaaaa tcggttttgt
     2041 ttgaagggag aaatagaatt ggttgctcaa agcacagctt tgaggttgca gataaagctg
     2101 acgtgg
//
LOCUS       DBERDS010000090         2090 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.090, whole genome shotgun sequence.
ACCESSION   DBERDS010000090 DBERDS010000000
VERSION     DBERDS010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.090"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..286)
                     /locus_tag="ACL73E_001991"
     CDS             complement(<1..286)
                     /locus_tag="ACL73E_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGS0801881.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDTRFKRLVGVQRTTFKEML
                     AVLKTAYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIAAVFCIHES"
     gene            complement(231..413)
                     /locus_tag="ACL73E_001992"
     CDS             complement(231..413)
                     /locus_tag="ACL73E_001992"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGS0801882.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            682..>2090
                     /gene="pcpA"
                     /locus_tag="ACL73E_001993"
     CDS             682..>2090
                     /gene="pcpA"
                     /locus_tag="ACL73E_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGS0801883.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKGTKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKG"
BASE COUNT          752 a          297 c          343 g          698 t
ORIGIN      
        1 tgctttcgtg gatacaaaaa acagccgcaa tttcttcata agtgcggtat tctcgcacat
       61 attgaagagt ggccataaga aggtcttcta gacttaattt aggttttcgt ccaccttttg
      121 cgtgtttaag ttgataagct gtttttaata cagctaacat ctctttaaaa gtggtacgct
      181 gaacaccaac aagacgctta aatcgtgtat cagttaattg tttacttgct tcataatttc
      241 gcagggagtc tattgactct ttggtaggtg tcaatgtttt tttcatctat cccgagaatt
      301 attttcccgc catttgtatt tgcaaatgct gagtaggttt cccagaaaga ctctggaaga
      361 ttgtttttag cttttttgta ttctaaatca accccttcaa attttaagtc catatttttc
      421 ctttacatct gttttttgtg gttctggtat ttgttcaagt tgagtgataa tatagcgaat
      481 tgaatttcga gagtttttac tcagttaatt tttcttgact taaaatttaa aaatgatata
      541 ctgtgtttat ggagagatga caatttataa aatgtactac tctattctac tagataatga
      601 ttgaataaaa ctttttataa caacggctag caaagttata attttatatc tattagaaaa
      661 taaatatgta aggaaattta aatgaaaaaa actacaatat tatcattaac tacagctgca
      721 gttattttag cagcatatgt ccctaatgaa ccaatcctag cagatactcc tagttcggaa
      781 gtaatcaaag agactaaagt tggaagtatt attcaacaaa ataatatcaa atataaggtt
      841 ctaactgtag aaggtaacat aggaactgtt caagtgggta atggagttac tcctgtagag
      901 tttgaagctg gtcaagatgg aaaaccattc acgattccta caaaaatcac agtaggtgat
      961 aaagtattta ccgttactga agtagctagt caagctttta gttattatcc agatgaaaca
     1021 ggtagaattg tctactatcc tagctctatt actatcccat caagcataaa aaaaatacaa
     1081 aaaaaaggct tccatggaag taaagctaaa actattattt ttgacaaagg tagtcagctg
     1141 gagaaaattg aagatagagc ttttgatttt tctgaattag aagagattga attgcctgca
     1201 tctctagaat atattggaac aagtgcattt tcttttagtc aaaaattgaa aaagctaacc
     1261 ttttcctcaa gttcaaaatt agaattaata tcacatgagg cttttgctaa tttatcaaat
     1321 ttagagaaac taacattacc aaaatcggtt aaaacattag gaagtaatct atttagactc
     1381 actactagct taaaacatgt tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat
     1441 ggtgttttgt tttcaaaaga taaaacccaa ttaatttatt atccaagtca aaaaaatgac
     1501 gaaagttata aaacgcctaa ggggacaaaa gaacttgcat catattcgtt taataaaaat
     1561 tcttacttga aaaaactcga attgaatgaa ggtttagaaa aaattggtac ttttgcattt
     1621 gcagatgcga ttaaacttga agaaattagc ttaccaaata gtttagaaac tattgaacgt
     1681 ttagcctttt acggtaattt agaattaaaa gaacttatat taccagataa tgttaaaaat
     1741 tttggtaaac acgttatgaa cggtttacca aaattaaaaa gtttaacaat tggtaataat
     1801 atcaactcat tgccgtcctt cttcctaagt ggcgtcttag attcattaaa ggaaattcat
     1861 attaagaata aaagtacaga gttttctgtg aaaaaagata catttgcaat tcctgaaact
     1921 gttaagttct atgtaacatc agaacatata aaagatgttc ttaaatcaaa tttatctact
     1981 agtaatgata tcattgttga aaaagtagat aatataaaac aagaaactga tgtagctaaa
     2041 cctaaaaaga attctaatca gggagtagtt ggttgggtta aagacaaagg
//
LOCUS       DBERDS010000091         1676 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.091, whole genome shotgun sequence.
ACCESSION   DBERDS010000091 DBERDS010000000
VERSION     DBERDS010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.091"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            74..530
                     /locus_tag="ACL73E_001994"
                     /pseudo
     CDS             74..530
                     /locus_tag="ACL73E_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            695..994
                     /locus_tag="ACL73E_001995"
     CDS             695..994
                     /locus_tag="ACL73E_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGS0801884.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1255..1578
                     /gene="tnpB"
                     /locus_tag="ACL73E_001996"
     CDS             1255..1578
                     /gene="tnpB"
                     /locus_tag="ACL73E_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGS0801885.1"
                     /translation="MMILLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKYRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          564 a          331 c          293 g          488 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttca ctataataat aacgatacta
       61 gataatgagg aaaatgcaat ggcaaaccca actttcggag aaaaaaagcg aatacagact
      121 atattgctcg ctatggcgta tatgcagtta tccctaatcc tgaacaaaaa caaattgttc
      181 ttgttcaaga accaaatggt gcttggttcc taccatgtgg agaaattgaa gcaggtgaaa
      241 atcatcagga agccctaaag cgtgagttga ttgaagagct tggtttcaca gcagaaattg
      301 gtacctatta cggacaagct gacgaatatt tctattctcg tcatcgtgat acctactact
      361 acaatcctgc ctacctctat gaagcaactt ctttcaaaga agtacaaaag ccactagaaa
      421 actttaatca tattgcctgg ttccctattg acgaggctat ccaaaacctt aaacgtggta
      481 gccataaatg ggccattgaa tcttggaaaa aacagcataa gattggctaa tactcttcga
      541 aaataaaatt caaaccacgt cagcgtcgcc ttaccgtact caagtatagc ctgcggctat
      601 cttcctagtt tgctctttga ttttcattga gtataaatca agcgacttta ttcaaaaagt
      661 gctataatag aattagaaaa tcggaggaaa tattatgaag cttatcaata cgacaaactc
      721 acactcgcaa ctggtaaaaa gtcagctaga aagtaccgat gcaacccttg ttgaggttta
      781 ttctgcaggg aatacagatg ttatttttac ccaagctccg cttcactatg aaatcctcat
      841 ctcaaacaaa caccgtgcta ttcgtgagcc tgaaatcgaa accattcaag aatttttctt
      901 gaaacgtaaa attgataaga cctctgttga tgaagccaat atcaagacac tctactcaga
      961 gaaattaatt ggaatttcaa tcccaatcaa gtaagaaaat tgagtaaaaa ctcgatttga
     1021 gagaaagtcc aataagtctt tccataacaa aacgcatagt aacaagagtt tctacaccca
     1081 ctattatacg tttttatcat tttgaaatct gctgctaatc aatgaagaag caaagatcaa
     1141 actaggcagc tagttacaag ttacgtaagc gcgtcataac aaggtatcta tcctaattcc
     1201 ccaacttcca gtatactaga taaaaaataa ttatcagagg aaaggtattg tactatgatg
     1261 attctactaa gtgatttagg tcaagttcac cttgtttgtg gcaagacaga tatgaggcag
     1321 ggaatagact cattagccta tgtagttaaa acccactttg aattggatcc tttctccggt
     1381 caagtctttc tcttttgtgg tggacgtaaa taccgcttta aagccctcta ctgggatggt
     1441 caaggatttt ggctactata taaacgcttt gagaacggca gactgacttg gcccagtaca
     1501 gaaaaggatg tcaaagctct cacatctgaa caagtagact ggcttatgaa gggcttttct
     1561 atcactcccc aaatatagtg gatttaaact agaatagtac acctctactt ctaaaacatt
     1621 gttagaaatc aatttgactg tcctgatcga tttgtactgt tcttatttca ttttac
//
LOCUS       DBERDS010000092         1591 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.092, whole genome shotgun sequence.
ACCESSION   DBERDS010000092 DBERDS010000000
VERSION     DBERDS010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.092"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(83..763)
                     /locus_tag="ACL73E_001997"
                     /pseudo
     CDS             complement(83..763)
                     /locus_tag="ACL73E_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(851..1372)
                     /locus_tag="ACL73E_001998"
                     /pseudo
     CDS             complement(851..1372)
                     /locus_tag="ACL73E_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1392..1487)
                     /locus_tag="ACL73E_001999"
                     /pseudo
     CDS             complement(1392..1487)
                     /locus_tag="ACL73E_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004608003.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          427 a          353 c          303 g          508 t
ORIGIN      
        1 aattgtaacc gtccaataac gaagtatatt gaaaaatctc cagactagag aactcacgga
       61 tagttcctaa tctggagatt tcttatttgc acttttcttg tacaacttta gtccacggta
      121 aataggcctc taaaacctct ttgtttacga gagtttcctc gtttggaaga cattctagaa
      181 gataggatag atatttctca ctatttagtt gatgacgttt agctgtttcc aataagctca
      241 taataatagc tcttgcttta gctccttcaa aaactttgag aaaacaacca ccctcgcttt
      301 tttaaactga gcttaggcta aaagagtcca gtggactctt ttactccgtc ccataaccaa
      361 tgatttaatg gcgcgttcag ctagattatt ggaaaggacc agatgtccgt cttttaaaat
      421 ggtcttaaag gtttcttcat acttgaggct gtattcaatt gcccttccta gttttgaacc
      481 cgataaaact gactgacgac ggcaccaagc aaagaagtct tctattaggg gttggagctc
      541 ttcttgacgt ttctgtagtc gttcatcagc tggcaaagcc tcccagtctc tttccaagga
      601 aaataactga tcacaatagg ctaatccttt agctcctaaa gatgatttat ccgcttgctt
      661 ggggggcgct tcaaaaaact tccttctcac atgtgcccaa catccaacaa gttcagcttc
      721 tgccagttga ctgacgataa gcttctagcg gttcgcagtt taccaagctt agcgtcgcct
      781 tgctcctaaa ccttggactg ctatcgcata ggcagaacta gaggactaaa gtcctaagtt
      841 actgccgcaa catgtcacaa tgcacatagc cagaataatc tcctaggaat tcttgtacta
      901 ctaaaccact ccgacgctga tcatggtggt acagcgtgat tgcttgattt tcagctttcc
      961 cagacaaaaa ggtccaatag taggtcagct gactatcact ctctagcacc ctataagaag
     1021 tttcatctgc atgaagtaag ggcttgagtc aatagtctcg ttataaaggg gctttaggaa
     1081 taggagcttt cacgatttta tcactcggat ttttatcact gcatgcttgg catttgtaag
     1141 cgtgttggat atgatctatg cgttttaatt gcgcaggaat aaagaccaat tcttgtcctt
     1201 gaagactccc tccaatctct tttagatctc cctgacaatc agggcaaatc ctctcttcta
     1261 cttgatgatg aacttcttct gaatcaaatt gggcaagaag agcttggcgt ttccctttag
     1321 atttcttacg tttgtaggta atttcttctg tttcaactgg gaacatctcc atcttcctca
     1381 gatggagact cttcctcaaa aaggttgagt tgtccagagg ggcaaacact tttctcagag
     1441 gattttccat agagcttttg agtcagataa gccacttgtt cacgcagaag ggcaagttca
     1501 ttggtgagac tatcaattgt agcactctgt tgttgaatga ttttcaatct tcttccatga
     1561 gcttccctct ctgttttcta actttattat a
//
LOCUS       DBERDS010000093         1352 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.093, whole genome shotgun sequence.
ACCESSION   DBERDS010000093 DBERDS010000000
VERSION     DBERDS010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.093"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(196..483)
                     /locus_tag="ACL73E_002000"
                     /pseudo
     CDS             complement(196..483)
                     /locus_tag="ACL73E_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            482..745
                     /locus_tag="ACL73E_002001"
                     /pseudo
     CDS             482..745
                     /locus_tag="ACL73E_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            792..>1352
                     /locus_tag="ACL73E_002002"
     CDS             792..>1352
                     /locus_tag="ACL73E_002002"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative N-acetylmannosamine-6-phosphate
                     2-epimerase"
                     /protein_id="HGS0801886.1"
                     /translation="MSQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVD"
BASE COUNT          454 a          242 c          278 g          378 t
ORIGIN      
        1 cattgaggaa ataataaaaa tctatgggta atgttctgaa agtactttta ggttaggaga
       61 gaaatataat gatttttgaa aattgattca aaaaatagcg aattgtagaa aacgcttaac
      121 aaatggtgta taatagactt ccagcgaaac aaaatatgct acaataaacc tatgaattat
      181 aaagcaacct tatactcatc tgtcttcaca aagcattcta gtccatctcc gattaacgat
      241 ggactttatc atctccttct ccagtccttg tatgacatct tccaaagttc gaaaggcttt
      301 attcttaaat ccacgtttac gaatctcttt ccacacttat tcaatggggt tcatttctgg
      361 tgtgtatgga ggaataaatg caaagccaat attagtcgga atctttaagg cacttgattt
      421 atgccatata gcattgtcca taacgaataa aagataatca tctggataag cttgtgaaag
      481 cttggctgac agtggttatc aagggctcat gaagatatat cttcaagcac aaactccacg
      541 taaatccagc aaactcaagc cgctaacagc tgaagataaa gcctataacc atgcgctatc
      601 taaggagaga agcaaggttg agaatatttt tgccaaagta aaaacgttta aaatgttttc
      661 aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctgatat
      721 tatcaatcat gaactaggat tctagttttg caggaagtct aataaatgta taagaaaaag
      781 gaggaaaaag gatgtcacag attagcaaag aagccttgat tgagcaaatc aaagatggaa
      841 tcatcgtttc ttgtcaggct cttcctcatg aaccgcttta tacagaagcg ggaggggtga
      901 ttcccttgct ggtcaaagcg gctgagcaag gtggagcagt cggtatccga gcaaacagtg
      961 ttcgcgatat caaggaaatt aaggaagtca ctaaacttcc aatcattggg attatcaaac
     1021 gtgattatcc acctcaggaa cccttcatca cggctactat gaaagaagtt gatgaattgg
     1081 cagaactgga catcgaggtg attgctctgg attgtaccaa gcgtgaacgc tacgatggtt
     1141 tggaaattca agagttcatt cgtcaggtta aggagaaata tcctaatcag cttttgatgg
     1201 ctgatactag tatcttcgaa gaagggctag cagctgtaga agcaggaatt gactttgtcg
     1261 gaacaacctt atcaggctac acatcctaca gtccaaaagt agacggtcca gattttgaat
     1321 tgattaagaa actctgtgat gccggtgtag at
//
LOCUS       DBERDS010000094         1215 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.094, whole genome shotgun sequence.
ACCESSION   DBERDS010000094 DBERDS010000000
VERSION     DBERDS010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.094"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..403
                     /locus_tag="ACL73E_002003"
     CDS             <1..403
                     /locus_tag="ACL73E_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801887.1"
                     /translation="SKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDY
                     IYFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVR
                     YFTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            406..1077
                     /locus_tag="ACL73E_002004"
     CDS             406..1077
                     /locus_tag="ACL73E_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801888.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDAELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            1079..>1215
                     /locus_tag="ACL73E_002005"
     CDS             1079..>1215
                     /locus_tag="ACL73E_002005"
                     /inference="COORDINATES: protein motif:HMM:NF013530.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGS0801889.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     I"
BASE COUNT          483 a          135 c          186 g          411 t
ORIGIN      
        1 ctctaaaaat attgaaattt caggaaatta taaagggcac acagtgaaaa aaatactaaa
       61 aaaattcgct ttatactcag taattaccaa acttgatata acgaaagtaa atcatttatt
      121 gagaaatgat tatatctact ttttaatgaa ggaaattgac aatattacta aaaaatatcc
      181 aaagttaatt caaaagtacc ctagagatat cttgagtgat aggtatggaa taacaaatga
      241 agtatataga tacttaatcg gagagaattt acatataaaa attaatcata aattagatga
      301 ggttagatat tttacagata ttccatttat tgatacttca ctttctattg aagagtttga
      361 caaaatagtt tctaaaatat taaaaattaa agtgggaggg taactatgat aagattacca
      421 aataaattta aaggtaataa tataactcta gaagttaaac taaataaagc agttgatgct
      481 agtgtattat acccagatgt taagtctcta gatcaagaat tgtatcgaca actacaatca
      541 gtagaatcat tctatcttac cttttctgat atgtattcag aaattaatga aaataatgaa
      601 atcttatata cagaaataat ctttaagata cctctttgta ttggagaaga ttattttaat
      661 tttccggttg tatcatatgt ttcaaatccc tattcgttaa taagaggatt ttatctaggt
      721 tttcataagg aattggactg taactatgta tttgatgatg cagagcttca tttttttagg
      781 gaagggattt gtgaatttaa cttcgaattt aaaaatcaaa attcaatcat tacagcagaa
      841 ttaccaaggg agtataacta tcccttgatc ttgtttaata attccaatct ggttaatcaa
      901 tatggaaaat atactttgtt agacatagac aaatataaat tagagtctag aaagattttt
      961 gaatttccag aaatttctat cggtaacttt cttggaagtg aagcaaaatc aaatagggta
     1021 atttttagcc aagataaatt tcaaattaat ggtataaaga atatggaggt aaattagcat
     1081 gaaatcatta ttaataacag gtggagcagg atacatagga tcacatacag ttttggactt
     1141 gttagataat aattatgaag taacaatcat tgatgatttg agtaactcta agaaaaaagt
     1201 tattgagtct attaa
//
LOCUS       DBERDS010000095         1052 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.095, whole genome shotgun sequence.
ACCESSION   DBERDS010000095 DBERDS010000000
VERSION     DBERDS010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.095"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            815..1033
                     /locus_tag="ACL73E_002006"
                     /pseudo
     CDS             815..1033
                     /locus_tag="ACL73E_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          334 a          145 c          214 g          359 t
ORIGIN      
        1 tttagttggg aaaattgtta attcatttaa attgtaaact ttagagattc tctggagtta
       61 tggatgtcgt tccaatatgt gcacgttgga atgttagtgc ttatatgggg ggaacagaat
      121 cctctcttga ttgaagacaa gctagtcatt aggctggttt gtctttttgt caactgtagt
      181 gggttgatat aatagtatta gtgagtggga taaaagtttc atttagttta ttcagtacaa
      241 atttaacggg tcaagattta tatactagtg gtgtttttgg ggctgagaga agtatcttga
      301 ttttatgtgt ggtttttata cttacagttg ttctgctcca aagagcttgt agagaagaat
      361 tagctcataa aggagattga ttattttgat atcaaaaaaa tgcacaggat aacctgatgc
      421 atttttttag cgacaatgct tgctacttcc ttctgtcgaa tttagacaat tttaaataaa
      481 agaatgaaat attccctact gtatttttag acgaagaacg ttagttaata atactcaaat
      541 ttatttcaaa ctctttgatt agtatgaatt tagctctaca gaaaaataaa aaatgtgata
      601 aaaatttcaa ctactcttat ctataataaa gctacctgtt ctttgaaaat tgaatccact
      661 ccgtcttgat tagcgtgcct gtgtaagtag ggactgagag tatttccctg tgaagggcaa
      721 ctggcacaag acgtgtgtga gaattttcta acagacacgg agtttatcgt ttccagactc
      781 aaacgatgcg acaaactaga taaaggagtt aatcatgaag gtagtaaact tgtatgattt
      841 gaaacaaatg ggaaataaag gtggttgtac catccaattg attcatcact ttccttttgg
      901 tatgggctta ggacatctca aaaaagacta cattgaattt aaacgtgttg gtatctttga
      961 tgggaaagca gtagaagtta ctcttcgaga accttattcg agagatctac ttcaggttgt
     1021 caagtcaata aagtaactga caccatgagt at
//
LOCUS       DBERDS010000096          871 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.096, whole genome shotgun sequence.
ACCESSION   DBERDS010000096 DBERDS010000000
VERSION     DBERDS010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.096"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..109)
                     /locus_tag="ACL73E_002007"
     CDS             complement(<1..109)
                     /locus_tag="ACL73E_002007"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGS0801890.1"
                     /translation="MTIEPGQRIALVGQSGSGKSTLSKIPSGLYKIDTGK"
     gene            complement(234..420)
                     /locus_tag="ACL73E_002008"
                     /pseudo
     CDS             complement(234..420)
                     /locus_tag="ACL73E_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845777.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            381..>871
                     /locus_tag="ACL73E_002009"
     CDS             381..>871
                     /locus_tag="ACL73E_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0801891.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTDEKEVNHLI
                     KYAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHTKYQKTQTDFQQEI
                     KVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKIDVEPVFGQIKA
                     SLG"
BASE COUNT          288 a          178 c          151 g          254 t
ORIGIN      
        1 cttttcctgt atcaatctta tataatcctg atggtatttt tgataacgta ctttttcctg
       61 accccgattg accgactagt gcaattctct gtcctggctc aatagtcaaa tttaaatttt
      121 ctattacagg agctgagtct ttggaataag agaaagatag gtccttaata tctattctac
      181 ttcaaacgtt tctaaactat actccggaaa ataatttaac caataactat ctttcatcgt
      241 atcctccaac cagtactaag agtctgggac aatagtctct tatctccaaa aaaaagcgga
      301 tttgccgttg cttttttgca tggttgcgat agtcttggta aaatagaatt gcccaataaa
      361 ccatttagaa aggctatccc atgcatattc actataacac aaatcaaaca actttaccac
      421 tagaaatcag ttctttcttg ccgcaagacc atctcgtctt tactattgaa aaagtggtga
      481 ataccgatga aaaggaggta aaccatctga ttaaatatgc catgtttgat aaggaacaaa
      541 agagaggcta taaacagtca gctagaaact tagcgaattg gcactataat gacaaggagg
      601 atagctatac acatcctgat ggctggtatt atcgttttca ccataccaaa tatcagaaaa
      661 cacagacaga ctttcaacaa gaaatcaagg tttactacgc cgacgaacct gaatcagccc
      721 ctcaaaaggg actgtatatg aacgaacgct atcaaaactt gaaagctaaa gaatgtcagg
      781 cgcttttatc tccccaaggt agacagattt tcgctcaacg caagattgat gtggaacctg
      841 tctttgggca gataaaggct tctttgggtt a
//
LOCUS       DBERDS010000097          688 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.097, whole genome shotgun sequence.
ACCESSION   DBERDS010000097 DBERDS010000000
VERSION     DBERDS010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.097"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>688
                     /locus_tag="ACL73E_002010"
     CDS             <1..>688
                     /locus_tag="ACL73E_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801892.1"
                     /translation="YKRLYVKIISFPEIEENLRKIVREKYLKRFNKESFDSNDRKFFE
                     YHIKQQNTDIDIFEKLLSINVNELSTPKGDNKQLDILHFINSEMGSYFQCLISLFINH
                     SSYRDVIIQIINSVTDTDYREFAQGILLNEYNPNRINVTYNTFLGFAYYHSTITIEAA
                     DVFTDVVRNILNKKIEDNQILNKVYLVALERVDPTIESFSLSKNNYSQMINIIFTGDY
                     EFRYSKEWLGA"
BASE COUNT          282 a           76 c           99 g          231 t
ORIGIN      
        1 tataagagat tatatgtaaa aattatcagt tttcctgaaa tagaagaaaa tttgagaaag
       61 attgttagag aaaaatattt aaaaagattt aacaaagaaa gttttgattc taacgatcgg
      121 aaattctttg aatatcatat aaaacaacaa aatacggata tagatatttt tgaaaaatta
      181 cttagtatca atgtgaatga actctcaaca ccaaaaggtg ataataaaca attagatata
      241 cttcatttta taaatagtga aatgggatca tattttcaat gtttaatatc attatttata
      301 aatcattcaa gttatagaga tgtaattatt caaataataa attcagtaac agataccgat
      361 tatagggagt ttgctcaagg tattttatta aatgaataca atccaaacag aatcaatgta
      421 acttacaaca cctttttagg atttgcgtat tatcattcta caattactat cgaagctgcg
      481 gatgttttca cagatgtagt aaggaatatt ctaaacaaaa aaattgagga caatcaaatt
      541 cttaataaag tttatctagt tgctttagag agggtagatc caactattga atcattttct
      601 ttatcaaaga ataactatag tcaaatgata aacatcattt ttacaggaga ctatgaattt
      661 agatattcta aagaatggtt gggagcat
//
LOCUS       DBERDS010000098          670 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.098, whole genome shotgun sequence.
ACCESSION   DBERDS010000098 DBERDS010000000
VERSION     DBERDS010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.098"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..475
                     /locus_tag="ACL73E_002011"
                     /pseudo
     CDS             1..475
                     /locus_tag="ACL73E_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(594..667)
                     /locus_tag="ACL73E_002012"
     tRNA            complement(594..667)
                     /locus_tag="ACL73E_002012"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(631..633),aa:Asn,seq:gtt)
BASE COUNT          232 a          149 c           95 g          194 t
ORIGIN      
        1 atggagatga gctttattgc tcaagacttt gataagctca atatcataac tgttcttgag
       61 agcagaacac aagccatcat ccgaaatccc atgaatacaa ggctatcaag cgatactgaa
      121 agctcattca acaagatagt cagaaactga gtgataaacg attttatcgc cctacttttc
      181 gtatgcactt gactaataaa gaaattctag ataaactttt gagctattcc gaagacttga
      241 aacaccacta taatctctat cagctcttgc ttttccacct ctttttcaga ctctgtttaa
      301 aaccttcctc aaagataaag aaaaaatcgt caacggcctt caattacctt attccaacgc
      361 caaactggaa gccaccaata atctcatcaa acttatcaag tacaatgcct ttggttttag
      421 gaactttgaa aacttcaaaa aagaaaggac gaaatttgtc ctttctcaag cttagctttt
      481 cttcaaccca ctacagttga caaagagcca ctatttttgg ttcattttac tataacacga
      541 aatagattat tattacataa taaaaaagag gtctaaacct cttaactaaa ttactccgcc
      601 agtaggactc gaacctacga catcatgatt aacagtcatg cgctactacc aactgagcta
      661 tggcggatta
//
LOCUS       DBERDS010000099          642 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.099, whole genome shotgun sequence.
ACCESSION   DBERDS010000099 DBERDS010000000
VERSION     DBERDS010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.099"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>642
                     /locus_tag="ACL73E_002013"
     CDS             <1..>642
                     /locus_tag="ACL73E_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGS0801893.1"
                     /translation="KKDAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTAS
                     KIQDILSVAPRSIGTTSPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGN
                     RLEAVILAEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLR"
BASE COUNT          195 a          138 c          127 g          182 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactggc tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgaa aagcattcag aatataccta ccaactcttg acatgctacc
      241 ctaatcctca gaaaaggctt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa aattcaggat atcctctcag ttgcacctcg ttctatcgga acaacatctc
      361 ctgctcgtga attcgaaatc atcaaacatt acaagaggct cattgacaag gcggaaacat
      421 gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggtcact gggattggga
      481 atcgtttaga ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt gataatcctg
      541 ctcaattaca agctttcgct ggactggatt cttctattta tcagtcaggt cagattgatt
      601 tagctggaag aatgatcaaa cggggttccc ctcatctgcg gt
//
LOCUS       DBERDS010000100          638 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.100, whole genome shotgun sequence.
ACCESSION   DBERDS010000100 DBERDS010000000
VERSION     DBERDS010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.100"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            53..415
                     /locus_tag="ACL73E_002014"
     CDS             53..415
                     /locus_tag="ACL73E_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGS0801894.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          211 a           80 c          119 g          228 t
ORIGIN      
        1 acctgaggct agtttcctag tctgctcttt ggttttcatt gagtataaca cattgttaga
       61 agttggttta aattccctaa tcagtttgtt cacatttacc ttcgatatat tatatcccat
      121 agttaaggtt ggtcatacag atgattatag tcatggagcc gtaaaactta gtgtttcttt
      181 agttgacaaa gatgccatga aaaaaatatc tgtaactgta ataggatatt ttgaaataaa
      241 tatagatgaa aatatcaccg atattctata cgtaaatggt actgctattc tttatcctta
      301 tttacgttct attgtttcaa tagtttcggc aattgatagc agtgaagcaa tgttgctacc
      361 taccattaat gttttagagt tactagataa atctcaacct tttgaagaag aataatttat
      421 tagctcacta aattgagggt aaggaaaagt aaaagcagta agaaaaatgt cttgcattat
      481 acagcaacct tttgggaatg agtagatgga ttgaataaaa tttgattaag agtggatgat
      541 ttatctgtag attattattg gacagttagt cttgaagtag tctaagaatt aggttataat
      601 cagtagaagc cttgctaata atgaggaggt tagtttat
//
LOCUS       DBERDS010000101          619 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.101, whole genome shotgun sequence.
ACCESSION   DBERDS010000101 DBERDS010000000
VERSION     DBERDS010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.101"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            82..561
                     /locus_tag="ACL73E_002015"
     CDS             82..561
                     /locus_tag="ACL73E_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGS0801895.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          240 a           77 c          145 g          157 t
ORIGIN      
        1 ggagctaaag ggaacagaat ggagaaaatg gaacaaatgt gttttctaat ctgttagact
       61 gtatctagaa aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgtg
      121 tataagtgta gaaatgaata ttaccttcat ttatgggaat tgtcggattg ggaccaagaa
      181 ggcatgctct gcttacatga attgattagt agagaagaag gactggtaga cgatattcca
      241 cgtttaagga aatatttcaa aaccaagttt cgaaatcgaa ttttagacta tatccgtaag
      301 caggaaagtc agaagcgtag atacgataaa gaaccctatg aagaagtggg tgagatcagt
      361 catcgtataa gtgagggggg tctctggcta gatgattatt atctctttca tgaaacacta
      421 agagattata gaaacaaaca aagtaaagag aaacaagaag aactagaacg cgtcttaagc
      481 aatgaacgat ttcgagggcg tcaaagagta ttaagagact tacgcattgt gtttaaggag
      541 tttactatcc gtacccacta gtaagtcatg caaaaaaaat gaaaaaaatt agaaaaagta
      601 gttgacaaag tttgaaaag
//
LOCUS       DBERDS010000102          611 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.102, whole genome shotgun sequence.
ACCESSION   DBERDS010000102 DBERDS010000000
VERSION     DBERDS010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.102"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            1..611
                     /locus_tag="ACL73E_002016"
                     /pseudo
     CDS             1..611
                     /locus_tag="ACL73E_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiator protein A"
BASE COUNT          250 a           74 c          116 g          171 t
ORIGIN      
        1 tgaatatttt tataacagag aagcgaaaag atttaacttc ttaaaagtac cggagatatt
       61 agttgataga gaagaatttc ggggcttatc agcagaagca attatccttt attccatact
      121 tcttaaatag acaggaatgt catttaagaa taactggata gacaaggaag gcagagtatt
      181 tatctatttt actgtcgaag aaattatgaa aagaagaaat atctcaaagc caactgccat
      241 aaaaacatta gatgagcttg atgtaaaaaa aggaatagga ctgatcgaaa gagtaaggct
      301 tggacttggt aagccgaaca tcatttatgt taaagacttt atgagtatat ttcaggtaaa
      361 agaaaatgac ttacagaagt caaaaaactt aacttcagaa gtaaaagatt ttaacctcag
      421 aagtaaagaa aatgaacttc aagaggttaa gaaccttgac tctaactata tagagaataa
      481 taagagtaag tatagtaaga gagaatatag ttttggtgaa aacggacttg gaacatttca
      541 aaatgtgttt ttagctgctg aagatatatc ggatttacaa atcataatga actcacagct
      601 tgagaattac a
//
LOCUS       DBERDS010000103          452 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.103, whole genome shotgun sequence.
ACCESSION   DBERDS010000103 DBERDS010000000
VERSION     DBERDS010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.103"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..81
                     /locus_tag="ACL73E_002017"
     CDS             <1..81
                     /locus_tag="ACL73E_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGS0801896.1"
                     /translation="PILFCIPAMSVPVFDNIILPAKQNMV"
     gene            89..452
                     /locus_tag="ACL73E_002018"
                     /pseudo
     CDS             89..452
                     /locus_tag="ACL73E_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT          145 a           86 c           92 g          129 t
ORIGIN      
        1 ccaatcttat tctgtatccc agcaatgagc gttccagtat ttgacaatat tatacttcct
       61 gcgaaacaaa atatggtata gtagttctat gaatgatgaa gcaagtaaac aactaactga
      121 tgcacgattt aagcgtcttg ttggtgttca gcgtaccact tttgaagaga tgttagctgt
      181 attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta aattaagcct
      241 agaagacctt cttatggcca ctcttcaata gtgcgagaat atcgaactta tgaacaaatt
      301 gcggctgatt ttggtattca cgaaagcaac tttatccgtc ggagccaatg ggttgaagta
      361 actcttgttc aaagtggtgt tacggtttca agaactcctc tcagctctga ggacacggta
      421 atgattgatg cgacggaagt acaaatcaat cg
//
LOCUS       DBERDS010000104          411 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.105, whole genome shotgun sequence.
ACCESSION   DBERDS010000104 DBERDS010000000
VERSION     DBERDS010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.105"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            complement(<1..>411)
                     /locus_tag="ACL73E_002019"
     CDS             complement(<1..>411)
                     /locus_tag="ACL73E_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGS0801897.1"
                     /translation="CKSYIKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVA
                     FIVYVGAPILIVLANIISIAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFV
                     TSLIAFLLNIKIMALIYYSLEDILIDDMNLLGLIL"
BASE COUNT          163 a           64 c           50 g          134 t
ORIGIN      
        1 aagtattaac cccaaaagat tcatatcatc tattaaaata tcctctaaag agtagtatat
       61 taaagccata attttaatgt taagtaaaaa tgcaattaat gaagtaacaa atgtcaaaaa
      121 tatagcctca ccaactttaa tcttaaccat ctggtaatta gaagttccta aaatttcaaa
      181 ttgctgaatc tcaatccttt cttgatgcga tgacaaaaat gcaattgaaa taatatttgc
      241 aagtactatc aaaattggtg ctcctacata gacaataaat gctactttta gctctaaatc
      301 actgtcatct tgaaattgag atagtatatt ctgagaaatc atttgaaaac tagaaattag
      361 taatatagct cctgtaattg cagcactgat agattttata taagacttac a
//
LOCUS       DBERDS010000105          375 bp    DNA     linear   BCT 24-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC3 isolate 465393
            SAMN38107277-rid24774623.denovo.107, whole genome shotgun sequence.
ACCESSION   DBERDS010000105 DBERDS010000000
VERSION     DBERDS010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38107277
            Sequence Read Archive: SRR26673582
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002570805.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002570805.1
            Genome Coverage       :: 187x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 15:42:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,020
            CDSs (total)                      :: 1,981
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 73 of 147
            Pseudo Genes (incomplete)         :: 65 of 147
            Pseudo Genes (internal stop)      :: 43 of 147
            Pseudo Genes (multiple problems)  :: 31 of 147
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38107277-rid24774623.denovo.107"
                     /strain="GPSC3"
                     /isolate="465393"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2017"
                     /collected_by="UKHSA"
     gene            <1..>375
                     /locus_tag="ACL73E_002020"
     CDS             <1..>375
                     /locus_tag="ACL73E_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGS0801898.1"
                     /translation="KKDAHGIALKLLSDPNREQFQHDNRQVELKILTRHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTAS
                     KIQDILSVAPRSIGTTSPAREF"
BASE COUNT          124 a           85 c           64 g          102 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactgac tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgga aagcattcag aatataccta ccaactcttg acacgctacc
      241 ctaatcctca gaaaaggatt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa aattcaggat atcctctcag tcgcacctcg ttctatcgga acaacatctc
      361 ctgctcgtga attcg
//
